-
Rapid-onset dystonia-parkinsonism is associated with reduced cerebral blood flow without gray matter changes. Front Neurol. 2023; 14:1116723.
Whitlow CT, Atcheson KM, Snively BM, Cook JF, Kim J, Haq IU, Sweadner KJ, Ozelius LJ, Brashear A. PMID: 36779071; PMCID: PMC9909223.
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PubMed Mentions:
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Temperature instability of a mutation at a multidomain junction in Na,K-ATPase isoform ATP1A3 (p.Arg756His) produces a fever-induced neurological syndrome. J Biol Chem. 2023 01; 299(1):102758.
Arystarkhova E, Toustrup-Jensen MS, Holm R, Ko JK, Lee KE, Feschenko P, Ozelius LJ, Brashear A, Vilsen B, Sweadner KJ. PMID: 36462665; PMCID: PMC9860391.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Aligning academic medicine within the healthcare system: the APS-SPR virtual chat series. Pediatr Res. 2022 Feb 11.
Shanley T, Brashear A, Johnston SC. PMID: 35149847; PMCID: PMC8831878.
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PubMed Mentions:
1 Fields:
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AbobotulinumtoxinA provides flexibility for the treatment of cervical dystonia with 500�U/1�mL and 500�U/2�mL dilutions. Clin Park Relat Disord. 2021; 5:100115.
Lew MF, Hauser RA, Isaacson SH, Truong D, Patel AT, Brashear A, Ondo W, Maisonobe P, Dashtipour K, Bahroo L, Wietek S. PMID: 34888518; PMCID: PMC8636802.
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PubMed Mentions:
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Predictive modeling of spread in adult-onset isolated dystonia: Key properties and effect of tremor inclusion. Eur J Neurol. 2021 12; 28(12):3999-4009.
Wang M, Sajobi T, Morgante F, Adler C, Agarwal P, B?umer T, Berardelli A, Berman BD, Blumin J, Borsche M, Brashear A, Deik A, Duque K, Espay AJ, Ferrazzano G, Feuerstein J, Fox S, Frank S, Hallett M, Jankovic J, LeDoux MS, Leegwater-Kim J, Mahajan A, Malaty IA, Ondo W, Pantelyat A, Pirio-Richardson S, Roze E, Saunders-Pullman R, Suchowersky O, Truong D, Vidailhet M, Shukla AW, Perlmutter JS, Jinnah HA, Martino D. PMID: 34296504; PMCID: PMC9100858.
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PubMed Mentions: Fields:
Translation:
Humans
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A Multi-center Genome-wide Association Study of Cervical Dystonia. Mov Disord. 2021 12; 36(12):2795-2801.
Sun YV, Li C, Hui Q, Huang Y, Barbano R, Rodriguez R, Malaty IA, Reich S, Bambarger K, Holmes K, Jankovic J, Patel NJ, Roze E, Vidailhet M, Berman BD, LeDoux MS, Espay AJ, Agarwal P, Pirio-Richardson S, Frank SA, Ondo WG, Saunders-Pullman R, Chouinard S, Natividad S, Berardelli A, Pantelyat AY, Brashear A, Fox SH, Kasten M, Kr?mer UM, Neis M, B?umer T, Loens S, Borsche M, Zittel S, Maurer A, Gelderblom M, Volkmann J, Odorfer T, K?hn AA, Borngr?ber F, K?nig IR, Cruchaga C, Cotton AC, Kilic-Berkmen G, Freeman A, Factor SA, Scorr L, Bremner JD, Vaccarino V, Quyyumi AA, Klein C, Perlmutter JS, Lohmann K, Jinnah HA. PMID: 34320236; PMCID: PMC8688173.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Correction: Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study. PLoS One. 2021; 16(4):e0250475.
Patel AT, Lew MF, Dashtipour K, Isaacson S, Hauser RA, Ondo W, Maisonobe P, Wietek S, Rubin B, Brashear A. PMID: 33852647; PMCID: PMC8046252.
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PubMed Mentions: Fields:
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Longitudinal goal attainment with integrated upper limb spasticity management including repeat injections of botulinum toxin A: Findings from the prospective, observational Upper Limb International Spasticity (ULIS-III) cohort study. J Rehabil Med. 2021 02 24; 53(2):jrm00157.
Turner-Stokes L, Jacinto J, Fheodoroff K, Brashear A, Maisonobe P, Lysandropoulos A, Ashford S, Upper Limb International Spasticity (ULIS-III) study group. PMID: 33616192; PMCID: PMC8814868.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study. PLoS One. 2021; 16(2):e0245827.
Patel AT, Lew MF, Dashtipour K, Isaacson S, Hauser RA, Ondo W, Maisonobe P, Wietek S, Rubin B, Brashear A. PMID: 33524060; PMCID: PMC7850472.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Assessing the effectiveness of upper-limb spasticity management using a structured approach to goal-setting and outcome measurement: First cycle results from the ULIS-III Study. J Rehabil Med. 2021 Jan 01; 53(1):jrm00133.
Turner-Stokes L, Jacinto J, Fheodoroff K, Brashear A, Maisonobe P, Lysandropoulos A, Ashford S, Upper Limb International Spasticity-III (ULIS-III) study group. PMID: 33206198; PMCID: PMC8772374.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Misfolding, altered membrane distributions, and the unfolded protein response contribute to pathogenicity differences in Na,K-ATPase ATP1A3 mutations. J Biol Chem. 2021 Jan-Jun; 296:100019.
Arystarkhova E, Ozelius LJ, Brashear A, Sweadner KJ. PMID: 33144327; PMCID: PMC7949067.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Safety and Stability of Pulmonary Function in Patients with Decreased Respiratory Function Treated for Spasticity with OnabotulinumtoxinA. Toxins (Basel). 2020 10 19; 12(10).
Ayyoub Z, Brashear A, Banach M, Schoene R, Stringer W, Boodhoo T, Yushmanova I, Dimitrova R, Brin MF. PMID: 33086749; PMCID: PMC7589715.
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PubMed Mentions: Fields:
Translation:
Humans
-
Dystonia and Tremor: A Cross-Sectional Study of the Dystonia Coalition Cohort. Neurology. 2021 01 26; 96(4):e563-e574.
Shaikh AG, Beylergil SB, Scorr L, Kilic-Berkmen G, Freeman A, Klein C, Junker J, Loens S, Br?ggemann N, M?nchau A, B?umer T, Vidailhet M, Roze E, Bonnet C, Jankovic J, Jimenez-Shahed J, Patel N, Marsh L, Comella C, Barbano RL, Berman BD, Malaty I, Wagle Shukla A, Reich SG, Ledoux MS, Berardelli A, Ferrazzano G, Stover N, Ondo W, Pirio Richardson S, Saunders-Pullman R, Mari Z, Agarwal P, Adler C, Chouinard S, Fox SH, Brashear A, Truong D, Suchowersky O, Frank S, Factor S, Perlmutter J, Jinnah HA. PMID: 33046615; PMCID: PMC7905789.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Auditory-perceptual voice and speech evaluation in ATP1A3 positive patients. J Clin Neurosci. 2020 Nov; 81:133-138.
Moya-Mendez ME, Madden LL, Ruckart KW, Downes KM, Cook JF, Snively BM, Brashear A, Haq IU. PMID: 33222902; PMCID: PMC7683823.
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PubMed Mentions: Fields:
Translation:
Humans
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The Effect of Repeated abobotulinumtoxinA (Dysport�) Injections on Walking Velocity in Persons with Spastic Hemiparesis Caused by Stroke or Traumatic Brain Injury. PM R. 2021 05; 13(5):488-495.
Esquenazi A, Brashear A, Deltombe T, Rudzinska-Bar M, Krawczyk M, Skoromets A, O'Dell MW, Grandoulier AS, Vilain C, Picaut P, Gracies JM. PMID: 32741133; PMCID: PMC8246752.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Cardiac phenotype in ATP1A3-related syndromes: A multicenter cohort study. Neurology. 2020 11 24; 95(21):e2866-e2879.
Balestrini S, Mikati MA, ?lvarez-Garc?a-Rov?s R, Carboni M, Hunanyan AS, Kherallah B, McLean M, Prange L, De Grandis E, Gagliardi A, Pisciotta L, Stagnaro M, Veneselli E, Campistol J, Fons C, Pias-Peleteiro L, Brashear A, Miller C, Sam?es R, Brankovic V, Padiath QS, Potic A, Pilch J, Vezyroglou A, Bye AME, Davis AM, Ryan MM, Semsarian C, Hollingsworth G, Scheffer IE, Granata T, Nardocci N, Ragona F, Arzimanoglou A, Panagiotakaki E, Carrilho I, Zucca C, Novy J, Dziezyc K, Parowicz M, Mazurkiewicz-Beldzinska M, Weckhuysen S, Pons R, Groppa S, Sinden DS, Pitt GS, Tinker A, Ashworth M, Michalak Z, Thom M, Cross JH, Vavassori R, Kaski JP, Sisodiya SM. PMID: 32913013; PMCID: PMC7734736.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Efficacy and Safety of AbobotulinumtoxinA for the Treatment of Hemiparesis in Adults with Lower Limb Spasticity Previously Treated With Other Botulinum Toxins: A Secondary Analysis of a Randomized Controlled Trial. PM R. 2020 09; 12(9):853-860.
Esquenazi A, Stoquart G, Hedera P, Jacinto LJ, Dimanico U, Constant-Boyer F, Brashear A, Grandoulier AS, Vilain C, Picaut P, Gracies JM. PMID: 32108436; PMCID: PMC7540573.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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IncobotulinumtoxinA Treatment in Upper-Limb Poststroke Spasticity in the Open-Label Extension Period of PURE: Efficacy in Passive Function, Caregiver Burden, and Quality of Life. PM R. 2020 05; 12(5):491-499.
Marciniak C, Munin MC, Brashear A, Rubin BS, Patel AT, Slawek J, Hanschmann A, Hiersemenzel R, Elovic EP. PMID: 31647185.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Saving neurology: Once more with feeling. Neurology. 2019 12 03; 93(23):989-990.
Schor NF, Brashear A. PMID: 31690683.
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PubMed Mentions: Fields:
Translation:
Humans
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Factors in the disease severity of ATP1A3 mutations: Impairment, misfolding, and allele competition. Neurobiol Dis. 2019 12; 132:104577.
Arystarkhova E, Haq IU, Luebbert T, Mochel F, Saunders-Pullman R, Bressman SB, Feschenko P, Salazar C, Cook JF, Demarest S, Brashear A, Ozelius LJ, Sweadner KJ. PMID: 31425744; PMCID: PMC7397496.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Revising rapid-onset dystonia-parkinsonism: Broadening indications for ATP1A3 testing. Mov Disord. 2019 10; 34(10):1528-1536.
Haq IU, Snively BM, Sweadner KJ, Suerken CK, Cook JF, Ozelius LJ, Miller C, McCall WV, Whitlow CT, Brashear A. PMID: 31361359; PMCID: PMC6879786.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
Alternating Hemiplegia of Childhood in a Person of Malay Ethnicity with Diffusion Tensor Imaging Abnormalities. J Mov Disord. 2019 May; 12(2):132-134.
Tan AH, Ong TL, Ramli N, Tan LK, Lim JL, Azhan MA, Ahmad-Annuar A, Ibrahim KA, Abdul-Aziz Z, Ozelius LJ, Brashear A, Lim SY. PMID: 31158946; PMCID: PMC6547042.
View in:
PubMed Mentions:
1
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Genotype-structure-phenotype relationships diverge in paralogs ATP1A1, ATP1A2, and ATP1A3. Neurol Genet. 2019 Feb; 5(1):e303.
Sweadner KJ, Arystarkhova E, Penniston JT, Swoboda KJ, Brashear A, Ozelius LJ. PMID: 30842972; PMCID: PMC6384024.
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PubMed Mentions:
16
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IncobotulinumtoxinA Efficacy and Safety in Adults with Upper-Limb Spasticity Following Stroke: Results from the Open-Label Extension Period of a Phase 3 Study. Adv Ther. 2019 01; 36(1):187-199.
Marciniak C, Munin MC, Brashear A, Rubin BS, Patel AT, Slawek J, Hanschmann A, Hiersemenzel R, Elovic EP. PMID: 30484117; PMCID: PMC6318229.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Burnout in neurology: Extinguishing the embers and rekindling the joy in practice. Neurology. 2018 11 13; 91(20):907-908.
Brashear A, Vickrey BG. PMID: 30305444.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Gender bias in American Academy of Neurology recognition awards? Neurology. 2018 08 14; 91(7):291-292.
Graves JS, Brashear A. PMID: 30030327.
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PubMed Mentions: Fields:
Translation:
Humans
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Injectable DaxibotulinumtoxinA in Cervical Dystonia: A Phase 2 Dose-Escalation Multicenter Study. Mov Disord Clin Pract. 2018 May-Jun; 5(3):273-282.
Jankovic J, Truong D, Patel AT, Brashear A, Evatt M, Rubio RG, Oh CK, Snyder D, Shears G, Comella C. PMID: 30009213; PMCID: PMC6032882.
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PubMed Mentions:
16
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A 500 U/2 mL dilution of abobotulinumtoxinA vs. placebo: randomized study in cervical dystonia. Int J Neurosci. 2018 Jul; 128(7):619-626.
Lew MF, Brashear A, Dashtipour K, Isaacson S, Hauser RA, Maisonobe P, Snyder D, Ondo W. PMID: 29343142.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Efficacy and safety of abobotulinumtoxinA in spastic lower limb: Randomized trial and extension. Neurology. 2017 Nov 28; 89(22):2245-2253.
Gracies JM, Esquenazi A, Brashear A, Banach M, Kocer S, Jech R, Khatkova S, Benetin J, Vecchio M, McAllister P, Ilkowski J, Ochudlo S, Catus F, Grandoulier AS, Vilain C, Picaut P, International AbobotulinumtoxinA Adult Lower Limb Spasticity Study Group. PMID: 29093068; PMCID: PMC5705248.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCTClinical Trials
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Rehabilitation plus OnabotulinumtoxinA Improves Motor Function over OnabotulinumtoxinA Alone in Post-Stroke Upper Limb Spasticity: A Single-Blind, Randomized Trial. Toxins (Basel). 2017 07 11; 9(7).
Devier D, Harnar J, Lopez L, Brashear A, Graham G. PMID: 28696373; PMCID: PMC5535163.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Dose-Dependent Effects of AbobotulinumtoxinA (Dysport) on Spasticity and Active Movements in Adults With Upper Limb Spasticity: Secondary Analysis of a Phase 3 Study. PM R. 2018 01; 10(1):1-10.
O'Dell MW, Brashear A, Jech R, Lejeune T, Marque P, Bensmail D, Ayyoub Z, Simpson DM, Volteau M, Vilain C, Picaut P, Gracies JM. PMID: 28634000.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Efficacy and Safety of AbobotulinumtoxinA (Dysport) for the Treatment of Hemiparesis in Adults With Upper Limb Spasticity Previously Treated With Botulinum Toxin: Subanalysis From a Phase 3 Randomized Controlled Trial. PM R. 2017 12; 9(12):1181-1190.
Marciniak C, McAllister P, Walker H, Brashear A, Edgley S, Deltombe T, Khatkova S, Banach M, Gul F, Vilain C, Picaut P, Grandoulier AS, Gracies JM, International AbobotulinumtoxinA Adult Upper Limb Spasticity Study Group. PMID: 28625615.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
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Head drop after botox: Electrodiagnostic evaluation of iatrogenic botulinum toxicity. Clin Neurol Neurosurg. 2017 May; 156:1-3.
Szuch E, Caress JB, Paudyal B, Brashear A, Cartwright MS, Strowd RE. PMID: 28273554.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Research conference summary from the 2014 International Task Force on ATP1A3-Related Disorders. Neurol Genet. 2017 Apr; 3(2):e139.
Rosewich H, Sweney MT, DeBrosse S, Ess K, Ozelius L, Andermann E, Andermann F, Andrasco G, Belgrade A, Brashear A, Ciccodicola S, Egan L, George AL, Lewelt A, Magelby J, Merida M, Newcomb T, Platt V, Poncelin D, Reyna S, Sasaki M, Sotero de Menezes M, Sweadner K, Viollet L, Zupanc M, Silver K, Swoboda K. PMID: 28293679; PMCID: PMC5335249.
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PubMed Mentions:
24
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Poster 289 Patient Registry of Spasticity Care World Data Analysis Based on Physician Experience. PM R. 2016 Sep; 8(9S):S254.
Esquenazi A, Lee S, Mayer NH, Brashear A, Francisco GE, Yablon EE, Garreta R, Wissel J, Molteni F. PMID: 27673047.
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PubMed Mentions: Fields:
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Poster 288 Efficacy and Safety of Repeated AbobotulinumtoxinA Injections in Adults with Lower Limb Spasticity. PM R. 2016 Sep; 8(9S):S254.
Gracies JM, Esquenazi A, Brashear A, Edgley SR, O'Dell M, Hedera P, Rubin BS, Picaut P. PMID: 27673046.
View in:
PubMed Mentions:
1 Fields:
-
ATP1A3 Mutation in Adult Rapid-Onset Ataxia. PLoS One. 2016; 11(3):e0151429.
Sweadner KJ, Toro C, Whitlow CT, Snively BM, Cook JF, Ozelius LJ, Markello TC, Brashear A. PMID: 26990090; PMCID: PMC4798776.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin �1 subunit, Lamb1. Elife. 2015 Dec 24; 4.
Liu YB, Tewari A, Salameh J, Arystarkhova E, Hampton TG, Brashear A, Ozelius LJ, Khodakhah K, Sweadner KJ. PMID: 26705335; PMCID: PMC4749547.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial. Lancet Neurol. 2015 Oct; 14(10):992-1001.
Gracies JM, Brashear A, Jech R, McAllister P, Banach M, Valkovic P, Walker H, Marciniak C, Deltombe T, Skoromets A, Khatkova S, Edgley S, Gul F, Catus F, De Fer BB, Vilain C, Picaut P, International AbobotulinumtoxinA Adult Upper Limb Spasticity Study Group. PMID: 26318836.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
-
Novel mutations in ATP1A3 associated with catastrophic early life epilepsy, episodic prolonged apnea, and postnatal microcephaly. Epilepsia. 2015 Mar; 56(3):422-30.
Paciorkowski AR, McDaniel SS, Jansen LA, Tully H, Tuttle E, Ghoneim DH, Tupal S, Gunter SA, Vasta V, Zhang Q, Tran T, Liu YB, Ozelius LJ, Brashear A, Sweadner KJ, Dobyns WB, Hahn S. PMID: 25656163; PMCID: PMC4363281.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Rapid-Onset Dystonia-Parkinsonism in a Chinese Girl with a De Novo ATP1A3 c.2267G>A (p.R756H) Genetic Mutation. Mov Disord Clin Pract. 2015 Mar; 2(1):74-75.
Tan AH, Ozelius LJ, Brashear A, Lang AE, Ahmad-Annuar A, Tan CT, Lim SY. PMID: 30713883; PMCID: PMC6353356.
View in:
PubMed Mentions:
3
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Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Acta Neuropathol. 2014 Jul; 128(1):81-98.
Oblak AL, Hagen MC, Sweadner KJ, Haq I, Whitlow CT, Maldjian JA, Epperson F, Cook JF, Stacy M, Murrell JR, Ozelius LJ, Brashear A, Ghetti B. PMID: 24803225; PMCID: PMC4059967.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
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Distinct neurological disorders with ATP1A3 mutations. Lancet Neurol. 2014 May; 13(5):503-14.
Heinzen EL, Arzimanoglou A, Brashear A, Clapcote SJ, Gurrieri F, Goldstein DB, J?hannesson SH, Mikati MA, Neville B, Nicole S, Ozelius LJ, Poulsen H, Schyns T, Sweadner KJ, van den Maagdenberg A, Vilsen B, ATP1A3 Working Group. PMID: 24739246; PMCID: PMC4238309.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansAnimals
-
Heterogeneity in primary dystonia: lessons from THAP1, GNAL, and TOR1A in Amish-Mennonites. Mov Disord. 2014 May; 29(6):812-8.
Saunders-Pullman R, Fuchs T, San Luciano M, Raymond D, Brashear A, Ortega R, Deik A, Ozelius LJ, Bressman SB. PMID: 24500857; PMCID: PMC4013240.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Cognitive impairment in rapid-onset dystonia-parkinsonism. Mov Disord. 2014 Mar; 29(3):344-50.
Cook JF, Hill DF, Snively BM, Boggs N, Suerken CK, Haq I, Stacy M, McCall WV, Ozelius LJ, Sweadner KJ, Brashear A. PMID: 24436111; PMCID: PMC3960305.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
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ATP1A3 mutations: what is the phenotype? Neurology. 2014 Feb 11; 82(6):468-9.
Brashear A, Ozelius LJ, Sweadner KJ. PMID: 24431297.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Commentary. Mov Disord. 2013 Dec; 28(14):1939.
Brashear A. PMID: 24323532.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Coding for the use of botulinum toxin for movement disorders. Continuum (Minneap Minn). 2013 Oct; 19(5 Movement Disorders):1406-15.
Brashear A, Bushong L. PMID: 24092297.
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PubMed Mentions: Fields:
Translation:
Humans
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Treatment of cervical dystonia. Expert Opinion on Orphan Drugs. 2013 Oct 1; 1(8):599-606.
Brashear BA. .
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Publisher Site Mentions:
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A randomized, double-blind study of repeated incobotulinumtoxinA (Xeomin(�)) in cervical dystonia. J Neural Transm (Vienna). 2013 Dec; 120(12):1699-707.
Evidente VG, Fernandez HH, LeDoux MS, Brashear A, Grafe S, Hanschmann A, Comella CL. PMID: 23779062; PMCID: PMC3834167.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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Cost-effectiveness of onabotulinumtoxinA for the treatment of wrist and hand disability due to upper-limb post-stroke spasticity in Scotland. Eur J Neurol. 2013 May; 20(5):773-80.
Doan QV, Gillard P, Brashear A, Halperin M, Hayward E, Varon S, Lu ZJ. PMID: 23278954.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Patient registry of outcomes in spasticity care. Am J Phys Med Rehabil. 2012 Sep; 91(9):729-46.
Esquenazi A, Mayer N, Lee S, Brashear A, Elovic E, Francisco GE, Yablon S, PROS Study Group. PMID: 22469872.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Efficacy, tolerability, and immunogenicity of onabotulinumtoxina in a randomized, double-blind, placebo-controlled trial for cervical dystonia. Clin Neuropharmacol. 2012 Sep-Oct; 35(5):208-14.
Charles D, Brashear A, Hauser RA, Li HI, Boo LM, Brin MF, CD 140 Study Group. PMID: 22948497.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCTClinical Trials
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Psychiatric disorders in rapid-onset dystonia-parkinsonism. Neurology. 2012 Sep 11; 79(11):1168-73.
Brashear A, Cook JF, Hill DF, Amponsah A, Snively BM, Light L, Boggs N, Suerken CK, Stacy M, Ozelius L, Sweadner KJ, McCall WV. PMID: 22933743; PMCID: PMC3525305.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
ATP1A3 mutations in infants: a new rapid-onset dystonia-Parkinsonism phenotype characterized by motor delay and ataxia. Dev Med Child Neurol. 2012 Nov; 54(11):1065-7.
Brashear A, Mink JW, Hill DF, Boggs N, McCall WV, Stacy MA, Snively B, Light LS, Sweadner KJ, Ozelius LJ, Morrison L. PMID: 22924536; PMCID: PMC3465467.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
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New triggers and non-motor findings in a family with rapid-onset dystonia-parkinsonism. Parkinsonism Relat Disord. 2012 Jul; 18(6):737-41.
Barbano RL, Hill DF, Snively BM, Light LS, Boggs N, McCall WV, Stacy M, Ozelius L, Sweadner KJ, Brashear A. PMID: 22534615; PMCID: PMC3753404.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
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Relationship between disability and health-related quality of life and caregiver burden in patients with upper limb poststroke spasticity. PM R. 2012 Jan; 4(1):4-10.
Doan QV, Brashear A, Gillard PJ, Varon SF, Vandenburgh AM, Turkel CC, Elovic EP. PMID: 22200567.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Comment: The new mentoring and team leadership. Neurology. 2011 Aug 16; 77(7):685.
Brashear A. PMID: 21795648.
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PubMed Mentions: Fields:
Translation:
Humans
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A diagnostic test to distinguish psychogenic dystonia from organic dystonia? Neurology. 2011 Feb 15; 76(7):590-1.
Chen R, Brashear A. PMID: 21321331.
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Translation:
Humans
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Botulinum toxin type A: Exploring new indications. Drugs Today (Barc). 2010 Sep; 46(9):671-82.
Brashear A. PMID: 20967299.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Long-term efficacy and safety of botulinum toxin type A (Dysport) in cervical dystonia. Parkinsonism Relat Disord. 2010 Jun; 16(5):316-23.
Truong D, Brodsky M, Lew M, Brashear A, Jankovic J, Molho E, Orlova O, Timerbaeva S, Global Dysport Cervical Dystonia Study Group. PMID: 20359934.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Botulinum toxin type A in the treatment of patients with cervical dystonia. Biologics. 2009; 3:1-7.
Brashear A. PMID: 19707390; PMCID: PMC2726049.
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PubMed Mentions:
10
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Spasticity. Curr Treat Options Neurol. 2009 May; 11(3):153-61.
Brashear A, Lambeth K. PMID: 19364449.
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PubMed Mentions:
3
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Botulinum neurotoxin versus tizanidine in upper limb spasticity: a placebo-controlled study. J Neurol Neurosurg Psychiatry. 2009 Apr; 80(4):380-5.
Simpson DM, Gracies JM, Yablon SA, Barbano R, Brashear A, BoNT/TZD Study Team. PMID: 18977811.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Clinical comparisons of botulinum neurotoxin formulations. Neurologist. 2008 Sep; 14(5):289-98.
Brashear A. PMID: 18784598.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Long-term treatment with botulinum toxin type A in cervical dystonia has low immunogenicity by mouse protection assay. Mov Disord. 2008 Jul 30; 23(10):1353-60.
Brin MF, Comella CL, Jankovic J, Lai F, Naumann M, CD-017 BoNTA Study Group. PMID: 18546321.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2008 May 06; 70(19):1699-706.
Simpson DM, Blitzer A, Brashear A, Comella C, Dubinsky R, Hallett M, Jankovic J, Karp B, Ludlow CL, Miyasaki JM, Naumann M, So Y, Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. PMID: 18458230; PMCID: PMC5565261.
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PubMed Mentions:
131 Fields:
Translation:
Humans
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Repeated treatments with botulinum toxin type a produce sustained decreases in the limitations associated with focal upper-limb poststroke spasticity for caregivers and patients. Arch Phys Med Rehabil. 2008 May; 89(5):799-806.
Elovic EP, Brashear A, Kaelin D, Liu J, Millis SR, Barron R, Turkel C. PMID: 18452724.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Formation of neutralizing antibodies in patients receiving botulinum toxin type A for treatment of poststroke spasticity: a pooled-data analysis of three clinical trials. Clin Ther. 2007 Apr; 29(4):683-90.
Yablon SA, Brashear A, Gordon MF, Elovic EP, Turkel CC, Daggett S, Liu J, Brin MF. PMID: 17617291.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene. Brain. 2007 Mar; 130(Pt 3):828-35.
Brashear A, Dobyns WB, de Carvalho Aguiar P, Borg M, Frijns CJ, Gollamudi S, Green A, Guimaraes J, Haake BC, Klein C, Linazasoro G, Münchau A, Raymond D, Riley D, Saunders-Pullman R, Tijssen MA, Webb D, Zaremba J, Bressman SB, Ozelius LJ. PMID: 17282997.
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PubMed Mentions:
82 Fields:
Translation:
Humans
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Clinico-immunologic aspects of botulinum toxin type B treatment of cervical dystonia. Neurology. 2006 Dec 26; 67(12):2233-5.
Jankovic J, Hunter C, Dolimbek BZ, Dolimbek GS, Adler CH, Brashear A, Comella CL, Gordon M, Riley DE, Sethi K, Singer C, Stacy M, Tarsy D, Atassi MZ. PMID: 17190952.
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PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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The safety and tolerability of botulinum toxins for the treatment of cervical dystonia. Expert Opin Drug Saf. 2005 Mar; 4(2):241-9.
Brashear A. PMID: 15794717.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Chapter L1 Spasticity. . 2005 Jan 1; (Arch Phys Med Rehab7511994):679-686.
Brashear BA. .
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Publisher Site Mentions:
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Longitudinal assessment of the dose consistency of botulinum toxin type A (BOTOX) for cervical dystonia. Adv Ther. 2005 Jan-Feb; 22(1):49-55.
Brashear A, Hogan P, Wooten-Watts M, Marchetti A, Magar R, Martin J. PMID: 15943222.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Rapid-onset dystonia-parkinsonism: a fourth family consistent with linkage to chromosome 19q13. Mov Disord. 2004 Dec; 19(12):1506-10.
Zaremba J, Mierzewska H, Lysiak Z, Kramer P, Ozelius LJ, Brashear A. PMID: 15390049.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Dopamine transporter density in schizophrenic subjects with and without tardive dyskinesia. Schizophr Res. 2004 Dec 01; 71(2-3):371-5.
Yoder KK, Hutchins GD, Morris ED, Brashear A, Wang C, Shekhar A. PMID: 15474908.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Repeated dosing of botulinum toxin type A for upper limb spasticity following stroke. Neurology. 2004 Nov 23; 63(10):1971-3.
Gordon MF, Brashear A, Elovic E, Kassicieh D, Marciniak C, Liu J, Turkel C, BOTOX Poststroke Spasticity Study Group. PMID: 15557529.
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PubMed Mentions:
23 Fields:
Translation:
HumansCTClinical Trials
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Mutations in the Na+/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism. Neuron. 2004 Jul 22; 43(2):169-75.
de Carvalho Aguiar P, Sweadner KJ, Penniston JT, Zaremba J, Liu L, Caton M, Linazasoro G, Borg M, Tijssen MA, Bressman SB, Dobyns WB, Brashear A, Ozelius LJ. PMID: 15260953.
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PubMed Mentions:
183 Fields:
Translation:
HumansCells
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Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke. Arch Phys Med Rehabil. 2004 Jul; 85(7):1063-9.
Childers MK, Brashear A, Jozefczyk P, Reding M, Alexander D, Good D, Walcott JM, Jenkins SW, Turkel C, Molloy PT. PMID: 15241751.
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PubMed Mentions:
45 Fields:
Translation:
HumansCTClinical Trials
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Refined linkage to the RDP/DYT12 locus on 19q13.2 and evaluation of GRIK5 as a candidate gene. Mov Disord. 2004 Jul; 19(7):845-847.
Kamm C, Leung J, Joseph S, Dobyns WB, Brashear A, Breakefield XO, Ozelius LJ. PMID: 15254951.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Treatment of cervical dystonia with botulinum toxin. Operative Techniques in Otolaryngology-Head and Neck Surgery. 2004 Jun 1; 15(2):122-127.
Brashear BA. .
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Publisher Site Mentions:
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Botulinum toxin type B in upper-limb poststroke spasticity: a double-blind, placebo-controlled trial. Arch Phys Med Rehabil. 2004 May; 85(5):705-9.
Brashear A, McAfee AL, Kuhn ER, Fyffe J. PMID: 15129392.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Use of botulinum toxin type A in poststroke spasticity. Expert Rev Neurother. 2003 May; 3(3):271-7.
Brashear A. PMID: 19810893.
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PubMed Mentions: Fields:
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Botulinum toxin for spasticity after stroke. N Engl J Med. 2003 Jan 16; 348(3):258-9; author reply 258-9.
Dobkin BH. PMID: 12530439.
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PubMed Mentions: Fields:
Translation:
Humans
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Treatment with botulinum toxin type B for upper-limb spasticity. Arch Phys Med Rehabil. 2003 Jan; 84(1):103-7.
Brashear A, McAfee AL, Kuhn ER, Ambrosius WT. PMID: 12589629.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Inter- and intrarater reliability of the Ashworth Scale and the Disability Assessment Scale in patients with upper-limb poststroke spasticity. Arch Phys Med Rehabil. 2002 Oct; 83(10):1349-54.
Brashear A, Zafonte R, Corcoran M, Galvez-Jimenez N, Gracies JM, Gordon MF, McAfee A, Ruffing K, Thompson B, Williams M, Lee CH, Turkel C. PMID: 12370866.
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PubMed Mentions:
55 Fields:
Translation:
HumansCTClinical Trials
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Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after a stroke. N Engl J Med. 2002 Aug 08; 347(6):395-400.
Brashear A, Gordon MF, Elovic E, Kassicieh VD, Marciniak C, Do M, Lee CH, Jenkins S, Turkel C, Botox Post-Stroke Spasticity Study Group. PMID: 12167681.
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PubMed Mentions:
112 Fields:
Translation:
HumansCTClinical Trials
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Botulinum toxin type B: a new injectable treatment for cervical dystonia. Expert Opin Investig Drugs. 2001 Dec; 10(12):2191-9.
Brashear A. PMID: 11772315.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Cervical dystonia severity scale reliability study. Mov Disord. 2001 Nov; 16(6):1086-90.
O'Brien C, Brashear A, Cullis P, Truong D, Molho E, Jenkins S, Wojcieszek J, O'Neil T, Factor S, Seeberger L. PMID: 11748739.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Botulinum toxin type a neuromuscular blockade in the treatment of equinus foot deformity in cerebral palsy: a multicenter, open-label clinical trial. Pediatrics. 2001 Nov; 108(5):1062-71.
Koman LA, Brashear A, Rosenfeld S, Chambers H, Russman B, Rang M, Root L, Ferrari E, Garcia de Yebenes Prous J, Smith BP, Turkel C, Walcott JM, Molloy PT. PMID: 11694682.
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PubMed Mentions:
29 Fields:
Translation:
HumansCTClinical Trials
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The botulinum toxins in the treatment of cervical dystonia. Semin Neurol. 2001; 21(1):85-90.
Brashear A. PMID: 11346029.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Duration of effect of botulinum toxin type A in adult patients with cervical dystonia: a retrospective chart review. Clin Ther. 2000 Dec; 22(12):1516-24.
Brashear A, Watts MW, Marchetti A, Magar R, Lau H, Wang L. PMID: 11192142.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Patients' perception of stopping or continuing treatment of cervical dystonia with botulinum toxin type A. Mov Disord. 2000 Jan; 15(1):150-3.
Brashear A, Bergan K, Wojcieszek J, Siemers ER, Ambrosius W. PMID: 10634256.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The safety and efficacy of botulinum toxin type B in the treatment of patients with cervical dystonia: summary of three controlled clinical trials. Neurology. 2000; 55(12 Suppl 5):S29-35.
Lew MF, Brashear A, Factor S. PMID: 11188982.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Metrifonate treatment of AD: influence of APOE genotype. Neurology. 1999 Dec 10; 53(9):2010-6.
Farlow MR, Cyrus PA, Nadel A, Lahiri DK, Brashear A, Gulanski B. PMID: 10599773.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-responsive cervical dystonia. Neurology. 1999 Oct 22; 53(7):1439-46.
Brashear A, Lew MF, Dykstra DD, Comella CL, Factor SA, Rodnitzky RL, Trosch R, Singer C, Brin MF, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M. PMID: 10534248.
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PubMed Mentions:
52 Fields:
Translation:
HumansCTClinical Trials
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Rapid-onset dystonia-parkinsonism: linkage to chromosome 19q13. Ann Neurol. 1999 Aug; 46(2):176-82.
Kramer PL, Mineta M, Klein C, Schilling K, de Leon D, Farlow MR, Breakefield XO, Bressman SB, Dobyns WB, Ozelius LJ, Brashear A. PMID: 10443882.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Rapid onset dystonia-parkinsonism in a 14-year-old girl. Eur J Paediatr Neurol. 1999; 3(4):171-3.
Webb DW, Broderick A, Brashear A, Dobyns WB. PMID: 10476366.
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PubMed Mentions: Fields:
Translation:
Humans
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PET imaging of the pre-synaptic dopamine uptake sites in rapid-onset dystonia-parkinsonism (RDP). Mov Disord. 1999 Jan; 14(1):132-7.
Brashear A, Mulholland GK, Zheng QH, Farlow MR, Siemers ER, Hutchins GD. PMID: 9918356.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Impaired traffic sign recognition in drivers with dementia. American Journal of Alzheimer's Disease & Other Dementias®. 1998 May 1; 13(3):131-137.
Brashear BA, Unverzagt UF, Kuhn KE, Glazier GB, Farlow FM, Perkins PA, Hui HS. .
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Publisher Site Mentions:
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Cerebrospinal fluid homovanillic acid levels in rapid-onset dystonia-parkinsonism. Ann Neurol. 1998 Apr; 43(4):521-6.
Brashear A, Butler IJ, Hyland K, Farlow MR, Dobyns WB. PMID: 9546335.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Rapid-onset dystonia-parkinsonism: a report of clinical, biochemical, and genetic studies in two families. Adv Neurol. 1998; 78:335-9.
Brashear A, Butler IJ, Ozelius LJ, Kramer PI, Farlow MR, Breakefield XO, Dobyns WB. PMID: 9750930.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Comparison of treatment of tardive dystonia and idiopathic cervical dystonia with botulinum toxin type A. Mov Disord. 1998 Jan; 13(1):158-61.
Brashear A, Ambrosius WT, Eckert GJ, Siemers ER. PMID: 9452343.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Costs of treating dystonias and hemifacial spasm with botulinum toxin A. Pharmacoeconomics. 1997 Dec; 12(6):695-706.
Dodel RC, Kirchner A, Koehne-Volland R, Künig G, Ceballos-Baumann A, Naumann M, Brashear A, Richter HP, Szucs TD, Oertel WH. PMID: 10175981.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Focal dystonia after chemotherapy: a case series. J Neurooncol. 1997 Sep; 34(2):163-7.
Brashear A, Siemers E. PMID: 9210064.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Rapid-onset dystonia-parkinsonism in a second family. Neurology. 1997 Apr; 48(4):1066-9.
Brashear A, DeLeon D, Bressman SB, Thyagarajan D, Farlow MR, Dobyns WB. PMID: 9109901.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Ethylene oxide neurotoxicity: a cluster of 12 nurses with peripheral and central nervous system toxicity. Neurology. 1996 Apr; 46(4):992-8.
Brashear A, Unverzagt FW, Farber MO, Bonnin JM, Garcia JG, Grober E. PMID: 8780078.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Variable phenotype of rapid-onset dystonia-parkinsonism. Mov Disord. 1996 Mar; 11(2):151-6.
Brashear A, Farlow MR, Butler IJ, Kasarskis EJ, Dobyns WB. PMID: 8684384.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The influence of the reference electrode on CMAP configuration: leg nerve observations and an alternative reference site. Muscle Nerve. 1996 Jan; 19(1):63-7.
Brashear A, Kincaid JC. PMID: 8538671.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans. Am J Psychiatry. 1995 Oct; 152(10):1485-92.
Hendrie HC, Osuntokun BO, Hall KS, Ogunniyi AO, Hui SL, Unverzagt FW, Gureje O, Rodenberg CA, Baiyewu O, Musick BS. PMID: 7573588.
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PubMed Mentions:
115 Fields:
Translation:
Humans
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Percutaneous celiac plexus block with botulinum toxin A did not help the pain of chronic pancreatitis. J Clin Gastroenterol. 1995 Jun; 20(4):343-4.
Sherman S, Kopecky KK, Brashear A, Lehman GA. PMID: 7665834.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 1995 Jan; 37(1):118-20.
Hendrie HC, Hall KS, Hui S, Unverzagt FW, Yu CE, Lahiri DK, Sahota A, Farlow M, Musick B, Class CA, et al. PMID: 7818244.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Cross-national interrater agreement on the clinical diagnostic criteria for dementia. WHO-PRA Age-Associated Dementia Working Group, WHO-Program for Research on Aging, Health of Elderly Program. Neurology. 1994 Feb; 44(2):239-42.
Baldereschi M, Amato MP, Nencini P, Pracucci G, Lippi A, Amaducci L, Gauthier S, Beatty L, Quiroga P, Klassen G, et al. PMID: 8309565.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Rapid-onset dystonia-parkinsonism. Neurology. 1993 Dec; 43(12):2596-602.
Dobyns WB, Ozelius LJ, Kramer PL, Brashear A, Farlow MR, Perry TR, Walsh LE, Kasarskis EJ, Butler IJ, Breakefield XO. PMID: 8255463.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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The influence of the reference electrode on CMAP configuration. Muscle Nerve. 1993 Apr; 16(4):392-6.
Kincaid JC, Brashear A, Markand ON. PMID: 8455652.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Takayasu's Arteritis and Multiple Sclerosis. Journal of Neuroimaging. 1992 Jan 1; 2(1):36-38.
Brashear BA, Pascuzzi PR. .
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Publisher Site Mentions:
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The ventilatory response to intravenous and ventriculo-cisternal theophylline. Res Commun Chem Pathol Pharmacol. 1983 Jul; 41(1):79-94.
Wick JE, DeAtley RE, Oei TO, Glick MR, Brashear A, Baenziger J, Brashear RE. PMID: 6622832.
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PubMed Mentions: Fields:
Translation:
Animals
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A spectrophotometric, enzymatic assay for D-3-hydroxybutyrate that is not dependent on hydrazine. Anal Biochem. 1983 Jun; 131(2):478-82.
Brashear A, Cook GA. PMID: 6614481.
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PubMed Mentions:
5 Fields:
Translation:
Animals