Andrew Bremer

InstitutionUniversity of California Davis
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    1. Allister Price C, Argueta DA, Medici V, Bremer A, Lee V, Nunez MV, Chen GX, Keim NL, Havel PJ, Stanhope KL, DiPatrizio NV. Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII and ApoE in humans consuming high fructose corn syrup-sweetened beverage. Am J Physiol Endocrinol Metab. 2018 Apr 10. PMID: 29634315.
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    2. Havel PJ, Kievit P, Comuzzie AG, Bremer A. Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field. ILAR J. 2017 Dec 01; 58(2):251-268. PMID: 29216341.
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    3. Ronacher K, van Crevel R, Critchley JA, Bremer A, Schlesinger LS, Kapur A, Basaraba R, Kornfeld H, Restrepo BI. Defining a Research Agenda to Address the Converging Epidemics of Tuberculosis and Diabetes: Part 2: Underlying Biologic Mechanisms. Chest. 2017 07; 152(1):174-180. PMID: 28434937.
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    4. Cronise RJ, Sinclair DA, Bremer A. Response to: "If the Metabolic Winter Is Coming, When Will It Be Summer?" (Metab Syndr Relat Disord 2017;15:3). Metab Syndr Relat Disord. 2017 02; 15(1):4-5. PMID: 28165301.
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    5. Cronise RJ, Sinclair DA, Bremer A. Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease. Metab Syndr Relat Disord. 2017 02; 15(1):6-17. PMID: 27869525.
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    6. Triolo TM, Maahs DM, Pyle L, Slover R, Buckingham B, Cheng P, DiMeglio LA, Bremer A, Weinzimer SA, Chase HP. Effects of Frequency of Sensor-Augmented Pump Use on HbA1c and C-Peptide Levels in the First Year of Type 1 Diabetes. Diabetes Care. 2016 04; 39(4):e61-2. PMID: 26895885; PMCID: PMC4806776 [Available on 04/01/17].
    7. Stanhope KL, Medici V, Bremer A, Lee V, Lam HD, Nunez MV, Chen GX, Keim NL, Havel PJ. A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults. Am J Clin Nutr. 2015 Jun; 101(6):1144-54. PMID: 25904601; PMCID: PMC4441807.
    8. Buckingham B, Cheng P, Beck RW, Kollman C, Ruedy KJ, Weinzimer SA, Slover R, Bremer A, Fuqua J, Tamborlane W. CGM-measured glucose values have a strong correlation with C-peptide, HbA1c and IDAAC, but do poorly in predicting C-peptide levels in the two years following onset of diabetes. Diabetologia. 2015 Jun; 58(6):1167-74. PMID: 25773405; PMCID: PMC4416994.
    9. DiMeglio LA, Cheng P, Beck RW, Kollman C, Ruedy KJ, Slover R, Aye T, Weinzimer SA, Bremer A, Buckingham B. Changes in beta cell function during the proximate post-diagnosis period in persons with type 1 diabetes. Pediatr Diabetes. 2016 06; 17(4):237-43. PMID: 25720763; PMCID: PMC4551616 [Available on 06/01/17].
    10. Bremer A. Resveratrol use in metabolic syndrome. Metab Syndr Relat Disord. 2014 Dec; 12(10):493-5. PMID: 25229675; PMCID: PMC4251086.
    11. Cronise RJ, Sinclair DA, Bremer A. The "metabolic winter" hypothesis: a cause of the current epidemics of obesity and cardiometabolic disease. Metab Syndr Relat Disord. 2014 Sep; 12(7):355-61. PMID: 24918620; PMCID: PMC4209489.
    12. Buckingham B, Beck RW, Ruedy KJ, Cheng P, Kollman C, Weinzimer SA, DiMeglio LA, Bremer A, Slover R, Tamborlane WV. Effectiveness of early intensive therapy on ß-cell preservation in type 1 diabetes. Diabetes Care. 2013 Dec; 36(12):4030-5. PMID: 24130350; PMCID: PMC3836135.
    13. Bremer A, Stanhope KL, Graham JL, Cummings BP, Ampah SB, Saville BR, Havel PJ. Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques. J Nutr. 2014 Jan; 144(1):5-11. PMID: 24108131; PMCID: PMC3861794.
    14. Rezvani R, Cianflone K, McGahan JP, Berglund L, Bremer A, Keim NL, Griffen SC, Havel PJ, Stanhope KL. Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin and adiponectin: relationships with metabolic outcomes. Obesity (Silver Spring). 2013 Dec; 21(12):2471-80. PMID: 23512943; PMCID: PMC3732502.
    15. Brown DB, Loomba-Albrecht LA, Bremer A. Sexual precocity and its treatment. World J Pediatr. 2013 May; 9(2):103-11. PMID: 23677828.
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    16. Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG. Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation. J Biol Chem. 2013 Jun 14; 288(24):17360-71. PMID: 23640882; PMCID: PMC3682537.
    17. Buckingham BA, Beck RW, Ruedy KJ, Cheng P, Kollman C, Weinzimer SA, DiMeglio LA, Bremer A, Slover R, Cantwell M. The effects of inpatient hybrid closed-loop therapy initiated within 1 week of type 1 diabetes diagnosis. Diabetes Technol Ther. 2013 May; 15(5):401-8. PMID: 23570538; PMCID: PMC3643224.
    18. Bremer A, Jialal I. Adipose tissue dysfunction in nascent metabolic syndrome. J Obes. 2013; 2013:393192. PMID: 23653857; PMCID: PMC3638696.
    19. Kosova EC, Auinger P, Bremer A. The relationships between sugar-sweetened beverage intake and cardiometabolic markers in young children. J Acad Nutr Diet. 2013 Feb; 113(2):219-27. PMID: 23351625; PMCID: PMC4116486.
    20. Weiss R, Bremer A, Lustig RH. What is metabolic syndrome, and why are children getting it? Ann N Y Acad Sci. 2013 Apr; 1281:123-40. PMID: 23356701; PMCID: PMC3715098.
    21. Cummings BP, Bremer A, Kieffer TJ, D'Alessio D, Havel PJ. Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques. J Endocrinol. 2013 Feb; 216(2):207-15. PMID: 23151361.
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    22. Jialal I, Devaraj S, Kaur H, Adams-Huet B, Bremer A. Increased chemerin and decreased omentin-1 in both adipose tissue and plasma in nascent metabolic syndrome. J Clin Endocrinol Metab. 2013 Mar; 98(3):E514-7. PMID: 23303213.
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    23. Bremer A. The use of insulin in cystic fibrosis-related diabetes: a philosophical difference from the use of insulin in type 1 and type 2 diabetes. Pediatr Pulmonol. 2012 Nov; 47(11):1039-41. PMID: 22911489.
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    24. Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer A, Berglund L, McGahan JP, Keim NL, Havel PJ. Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans. Nutr Metab (Lond). 2012 Jul 24; 9(1):68. PMID: 22828276; PMCID: PMC3463498.
    25. Krakowiak P, Walker CK, Bremer A, Baker AS, Ozonoff S, Hansen RL, Hertz-Picciotto I. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics. 2012 May; 129(5):e1121-8. PMID: 22492772; PMCID: PMC3340592.
    26. Loomba-Albrecht LA, Bremer A, Wong A, Philipps AF. Neonatal cholestasis caused by hyperthyroidism. J Pediatr Gastroenterol Nutr. 2012 Mar; 54(3):433-4. PMID: 21691222.
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    27. Bremer A, Mietus-Snyder M, Lustig RH. Toward a unifying hypothesis of metabolic syndrome. Pediatrics. 2012 Mar; 129(3):557-70. PMID: 22351884; PMCID: PMC3289531.
    28. Bremer A. Insulin resistance in pediatric disease. Pediatr Ann. 2012 Feb 08; 41(2):e1-7. PMID: 22299621.
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    29. Bremer A. Metabolic disorders in the pediatric population. Pediatr Ann. 2012 Feb; 41(2):59. PMID: 22300182.
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    30. Mathew RP, Hernanz-Schulman M, Wang W, Saville B, Bremer A. Changes in carotid artery sonogram in premature adrenarche. J Pediatr Endocrinol Metab. 2012; 25(1-2):139-45. PMID: 22570963.
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    31. Mathewi RP, Duffy BD, Wang W, Saville BR, Bremer A. How much is enough? Evaluation of adrenal function in children who undergo growth hormone stimulation test. J Pediatr Endocrinol Metab. 2012; 25(7-8):733-9. PMID: 23155702.
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    32. Bremer A, Lustig RH. Effects of sugar-sweetened beverages on children. Pediatr Ann. 2012 Jan; 41(1):26-30. PMID: 22224718.
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    33. Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer A, Berglund L, McGahan JP, Keim NL, Havel PJ. Circulating concentrations of monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, and soluble leukocyte adhesion molecule-1 in overweight/obese men and women consuming fructose- or glucose-sweetened beverages for 10 weeks. J Clin Endocrinol Metab. 2011 Dec; 96(12):E2034-8. PMID: 21956423; PMCID: PMC3232623.
    34. Van Loan MD, Keim NL, Adams SH, Souza E, Woodhouse LR, Thomas A, Witbracht M, Gertz ER, Piccolo B, Bremer A, Spurlock M. Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in Overweight and Obese Adults: A Controlled Feeding Study. J Obes. 2011; 2011:989657. PMID: 21941636; PMCID: PMC3173723.
    35. Bremer A, Devaraj S, Afify A, Jialal I. Adipose tissue dysregulation in patients with metabolic syndrome. J Clin Endocrinol Metab. 2011 Nov; 96(11):E1782-8. PMID: 21865369; PMCID: PMC3205887.
    36. Stanhope KL, Bremer A, Medici V, Nakajima K, Ito Y, Nakano T, Chen G, Fong TH, Lee V, Menorca RI, Keim NL, Havel PJ. Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholesterol, and apolipoprotein-B in young men and women. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1596-605. PMID: 21849529; PMCID: PMC3200248.
    37. Bremer A, Stanhope KL, Graham JL, Cummings BP, Wang W, Saville BR, Havel PJ. Fructose-fed rhesus monkeys: a nonhuman primate model of insulin resistance, metabolic syndrome, and type 2 diabetes. Clin Transl Sci. 2011 Aug; 4(4):243-52. PMID: 21884510; PMCID: PMC3170136.
    38. Seeley HH, Loomba-Albrecht LA, Nagel M, Butani L, Bremer A. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis in three siblings having the same genetic lesion but different clinical presentations. World J Pediatr. 2012 May; 8(2):177-80. PMID: 21633858.
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    39. Stanhope KL, Griffen SC, Bremer A, Vink RG, Schaefer EJ, Nakajima K, Schwarz JM, Beysen C, Berglund L, Keim NL, Havel PJ. Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. Am J Clin Nutr. 2011 Jul; 94(1):112-9. PMID: 21613559; PMCID: PMC3127512.
    40. Bremer A, Byrd RS, Auinger P. Racial trends in sugar-sweetened beverage consumption among US adolescents: 1988-2004. Int J Adolesc Med Health. 2011; 23(3):279-86. PMID: 22191196.
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    41. Loomba-Albrecht LA, Bremer A, Styne DM, Glaser NS. High frequency of cardiac and behavioral complaints as presenting symptoms of hyperthyroidism in children. J Pediatr Endocrinol Metab. 2011; 24(3-4):209-13. PMID: 21648295.
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    42. Bremer A, Byrd RS, Auinger P. Differences in male and female adolescents from various racial groups in the relationship between insulin resistance-associated parameters with sugar-sweetened beverage intake and physical activity levels. Clin Pediatr (Phila). 2010 Dec; 49(12):1134-42. PMID: 21098536; PMCID: PMC4154583.
    43. Anuurad E, Bremer A, Berglund L. HIV protease inhibitors and obesity. Curr Opin Endocrinol Diabetes Obes. 2010 Oct; 17(5):478-85. PMID: 20717021; PMCID: PMC3076638.
    44. Bremer A. Polycystic ovary syndrome in the pediatric population. Metab Syndr Relat Disord. 2010 Oct; 8(5):375-94. PMID: 20939704; PMCID: PMC3125559.
    45. Loomba-Albrecht LA, Nagel M, Bremer A. Pseudohypoaldosteronism type 1 due to a novel mutation in the mineralocorticoid receptor gene. Horm Res Paediatr. 2010; 73(6):482-6. PMID: 20453518.
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    46. Devaraj S, Jialal I, Yun JM, Bremer A. Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications. Metabolism. 2011 Feb; 60(2):256-9. PMID: 20153491; PMCID: PMC2891423.
    47. Nelson RA, Bremer A. Insulin resistance and metabolic syndrome in the pediatric population. Metab Syndr Relat Disord. 2010 Feb; 8(1):1-14. PMID: 19943799.
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    48. Loomba-Albrecht LA, Jame M, Bremer A. A novel glucokinase gene mutation and its effect on glycemic/C-peptide fluctuations in a patient with maturity-onset diabetes of the young type 2. Diabetes Res Clin Pract. 2010 Mar; 87(3):e23-5. PMID: 20015564.
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    49. Tanyolaç S, Bremer A, Hodoglugil U, Movsesyan I, Pullinger CR, Heiner SW, Malloy MJ, Kane JP, Goldfine ID. Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects. Metab Syndr Relat Disord. 2009 Dec; 7(6):543-8. PMID: 19656007; PMCID: PMC3139525.
    50. Bremer A, Auinger P, Byrd RS. Sugar-Sweetened Beverage Intake Trends in US Adolescents and Their Association with Insulin Resistance-Related Parameters. J Nutr Metab. 2010; 2010. PMID: 20700405; PMCID: PMC2911593.
    51. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer A, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest. 2009 May; 119(5):1322-34. PMID: 19381015; PMCID: PMC2673878.
    52. Bremer A, Auinger P, Byrd RS. Relationship between insulin resistance-associated metabolic parameters and anthropometric measurements with sugar-sweetened beverage intake and physical activity levels in US adolescents: findings from the 1999-2004 National Health and Nutrition Examination Survey. Arch Pediatr Adolesc Med. 2009 Apr; 163(4):328-35. PMID: 19349561; PMCID: PMC4264593.
    53. Loomba-Albrecht LA, Glaser NS, Styne DM, Bremer A. An oral sulfonylurea in the treatment of transient neonatal diabetes mellitus. Clin Ther. 2009 Apr; 31(4):816-20. PMID: 19446154.
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    54. Swarbrick MM, Havel PJ, Levin AA, Bremer A, Stanhope KL, Butler M, Booten SL, Graham JL, McKay RA, Murray SF, Watts LM, Monia BP, Bhanot S. Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys. Endocrinology. 2009 Apr; 150(4):1670-9. PMID: 19164474; PMCID: PMC2659262.
    55. Albrecht LA, Gorges SW, Styne DM, Bremer A. Shwachman-Diamond syndrome presenting as hypoglycemia. Clin Pediatr (Phila). 2009 Mar; 48(2):212-4. PMID: 18832544.
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    56. Bremer A, Ranadive S, Conrad SC, Vallette-Kasic S, Rosenthal SM. Isolated adrenocorticotropic hormone deficiency presenting as an acute neurologic emergency in a peripubertal girl. J Pediatr Endocrinol Metab. 2008 Aug; 21(8):799-803. PMID: 18825881.
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    57. Bremer A, Miller WL. The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance. Fertil Steril. 2008 May; 89(5):1039-48. PMID: 18433749.
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    58. Bremer A, Ranadive S, Lustig RH. Outpatient transition of an infant with permanent neonatal diabetes due to a KCNJ11 activating mutation from subcutaneous insulin to oral glyburide. Pediatr Diabetes. 2008 Jun; 9(3 Pt 1):236-9. PMID: 18221420.
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    59. Bremer A, Nobuhara KK, Gitelman SE. Congenital hyperinsulinism in an infant caused by a macroscopic insulin-producing lesion. J Pediatr Endocrinol Metab. 2007 Mar; 20(3):437-40. PMID: 17451083.
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    60. Bremer A, Feldman BJ, Iezza G, Clark OH, Rosenthal SM. Report of a hürthle cell neoplasm in a peripubertal girl. Thyroid. 2007 Feb; 17(2):175-8. PMID: 17316121.
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