Calvin Hirsch

Title(s)Professor, General Medicine, Geriatrics, and Bioethics
SchoolSchool of Medicine
AddressPSSB/UCDMC
CA 95817
Phone916-734-7005
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    Collapse Biography 
    Collapse Education and Training
    Yale University, New Haven, CTBS05/1976Biology
    Univ. of Connecticut School of Medicine, Farmington, CTMD05/1980Medicine
    Mount Zion Hospital and Medical Center, San Francisco, CA06/1983Internal Medicine
    Stanford University, Stanford, CA06/1987Robert Wood Johnson Clinical Scholar

    Collapse Overview 
    Collapse Overview
    Dr. Hirsch's research focuses on the epidemiology of age-associated chronic diseases and conditions and their independent association with incident functional impairment, frailty, and mortality. His work also addresses how health systems can improve the quality of care of older adults.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Caregiving and all-cause mortality in postmenopausal women: Findings from the Women's Health Initiative. J Am Geriatr Soc. 2024 01; 72(1):24-36. Chavan PP, Weitlauf JC, LaMonte MJ, Sisto SA, Tomita M, Gallagher-Thompson D, Shadyab AH, Bidwell JT, Manson JE, Kroenke CH, Hayden KM, Hirsch CH, Mouton CP, Cannell MB, Hovey KM, Wactawski-Wende J. PMID: 37936486; PMCID: PMC10841917.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Elevated Plasma Levels of Ketone Bodies Are Associated With All-Cause Mortality and Incidence of Heart Failure in Older Adults: The CHS. J Am Heart Assoc. 2023 09 05; 12(17):e029960. Niezen S, Connelly MA, Hirsch C, Kizer JR, Benitez ME, Minchenberg S, Perez-Matos MC, Jiang ZG, Mukamal KJ. PMID: 37609928; PMCID: PMC10547348.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Fasting and Post-Load Glucose and Non-Esterified Fatty Acids and Risk of Heart Failure and Its Subtypes in Older Adults. J Gerontol A Biol Sci Med Sci. 2023 Jul 08; 78(7):1164-1171. Oesterle A, Buzkova P, Pellegrini CN, Hirsch C, Tracy RP, Siscovick DS, Djousse L, Mukamal KJ, Kizer JR. PMID: 36373954; PMCID: PMC10329227.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Social networks, social support, and life expectancy in older adults: the Cardiovascular Health Study. Arch Gerontol Geriatr. 2023 08; 111:104981. Bhatia R, Hirsch C, Arnold AM, Newman AB, Mukamal KJ. PMID: 36965200.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Circulating Androgen Concentrations and Risk of Incident Heart Failure in Older Men: The Cardiovascular Health Study. J Am Heart Assoc. 2022 Nov; 11(21):e026953. Njoroge JN, Tressel W, Biggs ML, Matsumoto AM, Smith NL, Rosenberg E, Hirsch CH, Gottdiener JS, Mukamal KJ, Kizer JR. PMID: 36285783; PMCID: PMC9673636.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Statins and Cognitive Decline in the Cardiovascular Health Study: A Comparison of Different Analytical Approaches. J Gerontol A Biol Sci Med Sci. 2022 05 05; 77(5):994-1001. Zeki Al Hazzouri A, Jawadekar N, Grasset L, Kaiser P, Kezios K, Calonico S, Glymour M, Hirsch C, Arnold AM, Varadhan R, Odden MC. PMID: 34331536; PMCID: PMC9071443.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Body Composition and Incident Heart Failure in Older Adults: Results From 2 Prospective Cohorts. J Am Heart Assoc. 2022 01 04; 11(1):e023707. Zhang L, Bartz TM, Santanasto A, Djoussé L, Mukamal KJ, Forman DE, Hirsch CH, Newman AB, Gottdiener JS, Kizer JR. PMID: 34927442; PMCID: PMC9075203.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. In patients with dementia and depression, several nondrug interventions vs. usual care reduce depression symptoms. Ann Intern Med. 2021 08; 174(8):JC89. Hirsch C. PMID: 34339230.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Cardiovascular damage phenotypes and all-cause and CVD mortality in older adults. Ann Epidemiol. 2021 11; 63:35-40. Miller LM, Wu C, Hirsch CH, Lopez OL, Cushman M, Odden MC. PMID: 34339835; PMCID: PMC8562895.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Associations of Serum Nonesterified Fatty Acids With Coronary Heart Disease Mortality and Nonfatal Myocardial Infarction: The CHS (Cardiovascular Health Study) Cohort. J Am Heart Assoc. 2021 03 16; 10(6):e019135. Huang NK, Bužková P, Matthan NR, Djoussé L, Hirsch CH, Kizer JR, Longstreth WT, Mukamal KJ, Lichtenstein AH. PMID: 33682438; PMCID: PMC8174223.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    11. Daily aspirin for primary prevention increased risk for major GI bleeding in healthy older adults. Ann Intern Med. 2021 01; 174(1):JC4. Hirsch C. PMID: 33395330.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    12. In older adults with a history of falls, interventions to reduce use of fall risk-increasing drugs do not reduce falls. Ann Intern Med. 2020 06 16; 172(12):JC68. Hirsch C. PMID: 32539505.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. In older adults with acute ischemic stroke, the Clinical Frailty Scale predicted mortality at 28 days. Ann Intern Med. 2020 05 19; 172(10):JC57. Hirsch C. PMID: 32422086.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. In dementia with aggression and agitation, several interventions help vs usual care. Ann Intern Med. 2020 03 17; 172(6):JC31. Hirsch C. PMID: 32176897.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The association of prediagnosis social support with survival after heart failure in the Cardiovascular Health Study. Ann Epidemiol. 2020 02; 42:73-77. Kaiser P, Allen N, Delaney JAC, Hirsch CH, Carnethon M, Arnold AM, Odden MC. PMID: 31992494; PMCID: PMC7060020.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Pre-diabetes, diabetes and predictors of incident angina among older women and men in the Cardiovascular Health Study. Diab Vasc Dis Res. 2020 Jan-Feb; 17(1):1479164119888476. Mathenge N, Fan W, Wong ND, Hirsch C, Delaney CJ, Amsterdam EA, Koch B, Calara R, Gardin JM. PMID: 31778070; PMCID: PMC7510359.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Trends in Blood Pressure and High-Sensitivity Cardiac Troponin-T With Cardiovascular Disease: The Cardiovascular Health Study. Am J Hypertens. 2019 09 24; 32(10):1013-1020. Tehrani DM, Fan W, Nambi V, Gardin J, Hirsch CH, Amsterdam E, deFilippi CR, Polonsky T, Wong ND. PMID: 31232455; PMCID: PMC6758940.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Review: In adults without CVD, aspirin reduces CV events and increases major bleeding compared with no aspirin. Ann Intern Med. 2019 05 21; 170(10):JC53. Atencio A, Hirsch C. PMID: 31108515.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    19. Advanced glycation end product carboxymethyl-lysine and risk of incident peripheral artery disease in older adults: The Cardiovascular Health Study. Diab Vasc Dis Res. 2019 09; 16(5):483-485. Garg PK, Biggs ML, Barzilay J, Djousse L, Hirsch C, Ix JH, Kizer JR, Tracy RP, Newman AB, Siscovick DS, Mukamal KJ. PMID: 31064218; PMCID: PMC6697602.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. In healthy older adults, aspirin did not affect disability-free survival or CVD but increased death and bleeding. Ann Intern Med. 2019 01 15; 170(2):JC3. Hirsch C. PMID: 30641554.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    21. Association of Biomarker and Physiologic Indices With Mortality in Older Adults: Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):114-120. Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M, Jacob ME, Kritchevsky SB, Newman AB. PMID: 29659743; PMCID: PMC6298182.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Review: Postdischarge home interventions can increase or decrease falls in older adults. Ann Intern Med. 2018 07 17; 169(2):JC10. Hirsch C. PMID: 30014099.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Cerebrovascular Steal Phenomenon and Electroconvulsive Therapy: A Case Report and Review of the Literature. J ECT. 2018 06; 34(2):e20-e24. Hategan A, Hirsch CH. PMID: 29116947.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Review: In adults with normal cognition or MCI, drugs do not prevent or delay cognitive decline. Ann Intern Med. 2018 04 17; 168(8):JC39. Hirsch C. PMID: 29677246.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Comparing methods to address bias in observational data: statin use and cardiovascular events in a US cohort. Int J Epidemiol. 2018 02 01; 47(1):246-254. Kaiser P, Arnold AM, Benkeser D, Zeki Al Hazzouri A, Hirsch CH, Psaty BM, Odden MC. PMID: 29024975; PMCID: PMC5837201.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    26. In postmenopausal women with osteoporosis, romosozumab followed by alendronate reduced fractures vs alendronate alone. Ann Intern Med. 2018 01 16; 168(2):JC3. Hirsch C. PMID: 29335715.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Soluble Inflammatory Markers and Risk of Incident Fractures in Older Adults: The Cardiovascular Health Study. J Bone Miner Res. 2018 02; 33(2):221-228. Stojanovic D, Bužková P, Mukamal KJ, Heckbert SR, Psaty BM, Fink HA, Cauley JA, Wallace E, Curtis LH, Hirsch C, Budoff M, Li D, Young R, Jalal D, Delaney JA. PMID: 28976598; PMCID: PMC5809254.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    28. In older men with low testosterone levels and age-associated memory impairment, testosterone did not improve memory. Ann Intern Med. 2017 05 16; 166(10):JC56. Hirsch C. PMID: 28505640.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Emergency Department Pain Management Following Implementation of a Geriatric Hip Fracture Program. West J Emerg Med. 2017 Jun; 18(4):585-591. Casey SD, Stevenson DE, Mumma BE, Slee C, Wolinsky PR, Hirsch CH, Tyler K. PMID: 28611877; PMCID: PMC5468062.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    30. Review: 1-time ultrasonography screening reduces abdominal aortic aneurysm-related mortality and rupture. Ann Intern Med. 2017 03 21; 166(6):JC27. Hirsch C. PMID: 28320001.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    31. Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study. Cerebrovasc Dis Extra. 2016; 6(3):129-139. Garg PK, Koh WJH, Delaney JA, Halm EA, Hirsch CH, Longstreth WT, Mukamal KJ, Kucharska-Newton A, Polak JF, Curtis L. PMID: 27846618; PMCID: PMC5836156.
      View in: PubMed   Mentions: 2     Fields:    
    32. Can a Healthy Lifestyle Compress the Disabled Period in Older Adults? J Am Geriatr Soc. 2016 10; 64(10):1952-1961. Jacob ME, Yee LM, Diehr PH, Arnold AM, Thielke SM, Chaves PH, Gobbo LD, Hirsch C, Siscovick D, Newman AB. PMID: 27603679; PMCID: PMC5073015.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    33. Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults. J Am Geriatr Soc. 2016 06; 64(6):1242-9. Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH, Kaplan RC, Kritchevsky SB, Newman AB. PMID: 27321602; PMCID: PMC4922749.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Cardiovascular Disease, Mortality Risk, and Healthcare Costs by Lipoprotein(a) Levels According to Low-density Lipoprotein Cholesterol Levels in Older High-risk Adults. Clin Cardiol. 2016 Jul; 39(7):413-20. Zhao Y, Delaney JA, Quek RG, Gardin JM, Hirsch CH, Gandra SR, Wong ND. PMID: 27177347; PMCID: PMC5845436.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Incident Atrial Fibrillation and Disability-Free Survival in the Cardiovascular Health Study. J Am Geriatr Soc. 2016 Apr; 64(4):838-43. Wallace ER, Siscovick DS, Sitlani CM, Dublin S, Mitchell PH, Odden MC, Hirsch CH, Thielke S, Heckbert SR. PMID: 26926559; PMCID: PMC4840029.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    36. ACP Journal Club. Review: Calcium supplementation and risk for fracture in persons > 50 years of age. Ann Intern Med. 2016 Jan 19; 164(2):JC4. Hirsch C. PMID: 26784494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. ACP Journal Club. Review: Dietary or supplemental calcium increase BMD by ≤ 1.8% in persons > 50 years of age. Ann Intern Med. 2016 Jan 19; 164(2):JC5. Hirsch C. PMID: 26784495.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. The Physical and Behavioral Indicators of Elder Mistreatment and Neglect. . 2016 Jan 1; 185-195. Hirsch HC, Francis FD, Bourgeois BJ. .
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    39. The Chief Adverse Effects of Medications. . 2016 Jan 1; 161-183. Hirsch HC, Maharaj MS, Bourgeois BJ. .
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    40. Subacute or Intermediate Medical Settings. . 2016 Jan 1; 273-278. Bakerjian BD, Anglin AR, Hirsch HC. .
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    41. Emergency Medicine Settings. . 2016 Jan 1; 219-230. Tyler TK, Hirsch HC, Scher SL, Stevenson SD. .
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    42. Physical Examination. . 2016 Jan 1; 17-30. Woo WT, Hirsch HC. .
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    43. The Chief Physical Complaints. . 2016 Jan 1; 141-159. Hirsch HC, Woo WT. .
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    44. ACP Journal Club: a balance retraining exercise program reduced injurious falls in at-risk older community-dwelling women. Ann Intern Med. 2015 Nov 17; 163(10):JC2. Hirsch C. PMID: 26571256.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Predicting Future Years of Life, Health, and Functional Ability: A Healthy Life Calculator for Older Adults. Gerontol Geriatr Med. 2015 Jan-Dec; 1:2333721415605989. Diehr P, Diehr M, Arnold A, Yee LM, Odden MC, Hirsch CH, Thielke S, Psaty BM, Johnson WC, Kizer Md JR, Newman A. PMID: 28138467; PMCID: PMC5119805.
      View in: PubMed   Mentions: 5  
    46. ACP Journal Club. Review: Multicomponent nonpharmacologic interventions reduce incident delirium in inpatients. Ann Intern Med. 2015 Jul 21; 163(2):JC4. Hirsch C. PMID: 26192584.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. ACP Journal Club. In open-angle glaucoma, latanoprost improved visual field preservation. Ann Intern Med. 2015 Jun 16; 162(12):JC10. Hirsch C. PMID: 26075775.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Development and validation of a model to predict 5-year risk of death without ESRD among older adults with CKD. Clin J Am Soc Nephrol. 2015 Mar 06; 10(3):363-71. Bansal N, Katz R, De Boer IH, Peralta CA, Fried LF, Siscovick DS, Rifkin DE, Hirsch C, Cummings SR, Harris TB, Kritchevsky SB, Sarnak MJ, Shlipak MG, Ix JH. PMID: 25710804; PMCID: PMC4348680.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    49. ACP Journal Club: an elastic band exercise program improved fitness in older adults who use wheelchairs in nursing homes. Ann Intern Med. 2015 Feb 17; 162(4):JC3. Hirsch C. PMID: 25686190.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. In older adults, high- vs standard-dose influenza vaccine reduced laboratory-confirmed influenza. Ann Intern Med. 2015 Jan 20; 162(2):JC2. Hirsch C. PMID: 25599362.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Multisystem physiologic impairments and changes in gait speed of older adults. J Gerontol A Biol Sci Med Sci. 2015 Mar; 70(3):319-24. Rosso AL, Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Carlson MC, Rosano C, Kritchevsky SB, Newman AB. PMID: 25380599; PMCID: PMC4351395.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    52. Subclinical vascular disease burden and longer survival. J Am Geriatr Soc. 2014 Sep; 62(9):1692-8. Odden MC, Yee LM, Arnold AM, Sanders JL, Hirsch C, deFilippi C, Kizer JR, Inzitari M, Newman AB. PMID: 25243681; PMCID: PMC4176817.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    53. Testosterone and dihydrotestosterone and incident ischaemic stroke in men in the Cardiovascular Health Study. Clin Endocrinol (Oxf). 2014 Nov; 81(5):746-53. Shores MM, Arnold AM, Biggs ML, Longstreth WT, Smith NL, Kizer JR, Cappola AR, Hirsch CH, Marck BT, Matsumoto AM. PMID: 24645738; PMCID: PMC4169352.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    54. ACP Journal Club. Review: Cholinesterase inhibitors do not prevent dementia in patients with mild cognitive impairment. Ann Intern Med. 2014 Apr 15; 160(8):JC11. Hirsch C. PMID: 24733216.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. Testosterone, dihydrotestosterone, and incident cardiovascular disease and mortality in the cardiovascular health study. J Clin Endocrinol Metab. 2014 Jun; 99(6):2061-8. Shores MM, Biggs ML, Arnold AM, Smith NL, Longstreth WT, Kizer JR, Hirsch CH, Cappola AR, Matsumoto AM. PMID: 24628549; PMCID: PMC4037728.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    56. Around a quarter of all older people have disability during the last 2 years of life, with prevalence higher among women and those aged over 80 years. Evid Based Nurs. 2014 Oct; 17(4):124. Hirsch CH. PMID: 24482240.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    57. Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2014 Jun; 69(6):710-6. Whitson HE, Arnold AM, Yee LM, Mukamal KJ, Kizer JR, Djousse L, Ix JH, Siscovick D, Tracy RP, Thielke SM, Hirsch C, Newman AB, Zieman S. PMID: 24127427; PMCID: PMC4022092.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    58. Impact of inflammatory biomarkers on relation of high density lipoprotein-cholesterol with incident coronary heart disease: cardiovascular Health Study. Atherosclerosis. 2013 Dec; 231(2):246-51. Tehrani DM, Gardin JM, Yanez D, Hirsch CH, Lloyd-Jones DM, Stein PK, Wong ND. PMID: 24267235; PMCID: PMC3858257.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    59. ACP Journal Club. A 12-month, in-home exercise program delayed functional deterioration in Alzheimer disease. Ann Intern Med. 2013 Aug 20; 159(4):JC10. Hirsch C. PMID: 24026274.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    60. ACP Journal Club. Review: case management does not reduce unplanned hospital admissions compared with usual care in older persons. Ann Intern Med. 2013 Jun 18; 158(12):JC13. Hirsch C. PMID: 23778925.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Decline in health for older adults: five-year change in 13 key measures of standardized health. J Gerontol A Biol Sci Med Sci. 2013 Sep; 68(9):1059-67. Diehr PH, Thielke SM, Newman AB, Hirsch C, Tracy R. PMID: 23666944; PMCID: PMC3738029.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    62. ACP Journal Club. Ginkgo biloba extract did not reduce risk for Alzheimer disease in elderly patients with memory complaints. Ann Intern Med. 2013 Jan 15; 158(2):JC7. Hirsch C. PMID: 23318341.
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    63. ACP Journal Club. The Mini-Cog had sensitivity similar to the longer 3MS for detecting cognitive impairment or dementia. Ann Intern Med. 2012 Oct 16; 157(8):JC4-8. Hirsch C. PMID: 23070510.
      View in: PubMed   Mentions: 3     Fields:    
    64. Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study. J Clin Endocrinol Metab. 2012 Nov; 97(11):3944-50. Waring AC, Arnold AM, Newman AB, Bùzková P, Hirsch C, Cappola AR. PMID: 22879629; PMCID: PMC3485600.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    65. Predicting late-life disability and death by the rate of decline in physical performance measures. Age Ageing. 2012 Mar; 41(2):155-61. Hirsch CH, Buzková P, Robbins JA, Patel KV, Newman AB. PMID: 22156556; PMCID: PMC3280678.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    66. ACP Journal Club. Systematic pain management reduced agitation in nursing home residents with dementia. Ann Intern Med. 2011 Nov 15; 155(10):JC5-09. Hirsch C. PMID: 22084356.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    67. Serum 25-hydroxyvitamin D and physical function in older adults: the Cardiovascular Health Study All Stars. J Am Geriatr Soc. 2011 Oct; 59(10):1793-801. Houston DK, Tooze JA, Davis CC, Chaves PH, Hirsch CH, Robbins JA, Arnold AM, Newman AB, Kritchevsky SB. PMID: 22091492; PMCID: PMC3228270.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    68. Longitudinal changes in adiponectin and inflammatory markers and relation to survival in the oldest old: the Cardiovascular Health Study All Stars study. J Gerontol A Biol Sci Med Sci. 2011 Oct; 66(10):1100-7. Kizer JR, Arnold AM, Jenny NS, Cushman M, Strotmeyer ES, Ives DG, Ding J, Kritchevsky SB, Chaves PH, Hirsch CH, Newman AB. PMID: 21659339; PMCID: PMC3172562.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    69. Change in circulating adiponectin in advanced old age: determinants and impact on physical function and mortality. The Cardiovascular Health Study All Stars Study. J Gerontol A Biol Sci Med Sci. 2010 Nov; 65(11):1208-14. Kizer JR, Arnold AM, Strotmeyer ES, Ives DG, Cushman M, Ding J, Kritchevsky SB, Chaves PH, Hirsch CH, Newman AB. PMID: 20616148; PMCID: PMC2954239.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    70. Physical activity and years of healthy life in older adults: results from the cardiovascular health study. J Aging Phys Act. 2010 Jul; 18(3):313-34. Hirsch CH, Diehr P, Newman AB, Gerrior SA, Pratt C, Lebowitz MD, Jackson SA. PMID: 20651417; PMCID: PMC3978479.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    71. Higher physical activity during middle age is associated with increased odds of survival without cognitive or physical impairments in older women. Evid Based Nurs. 2010 Jul; 13(3):85-6. Hirsch C. PMID: 20584834.
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    72. Health benefits of increased walking for sedentary, generally healthy older adults: using longitudinal data to approximate an intervention trial. J Gerontol A Biol Sci Med Sci. 2010 Sep; 65(9):982-9. Diehr P, Hirsch C. PMID: 20484337; PMCID: PMC2920578.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    73. Cholinesterase inhibitors were associated with increased risk for syncope and its consequences in older persons with dementia. Ann Intern Med. 2009 Sep 15; 151(6):JC3-13. Hirsch C. PMID: 19755359.
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    74. Continued use of antipsychotic drugs increased long-term mortality in patients with Alzheimer disease. Evid Based Med. 2009 Aug; 14(4):115. Hirsch C. PMID: 19648431.
      View in: PubMed   Mentions: 2     Fields:    
    75. ACP Journal Club. Continued use of antipsychotic drugs increased long-term mortality in patients with Alzheimer disease. Ann Intern Med. 2009 Jun 16; 150(12):JC6-8. Hirsch C. PMID: 19528553.
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    76. Postmenopausal hormone therapy and regional brain volumes: the WHIMS-MRI Study. Neurology. 2009 Jan 13; 72(2):135-42. Resnick SM, Espeland MA, Jaramillo SA, Hirsch C, Stefanick ML, Murray AM, Ockene J, Davatzikos C. PMID: 19139364; PMCID: PMC2677493.
      View in: PubMed   Mentions: 115     Fields:    Translation:Humans
    77. Association between lower digit symbol substitution test score and slower gait and greater risk of mortality and of developing incident disability in well-functioning older adults. J Am Geriatr Soc. 2008 Sep; 56(9):1618-25. Rosano C, Newman AB, Katz R, Hirsch CH, Kuller LH. PMID: 18691275; PMCID: PMC2631090.
      View in: PubMed   Mentions: 131     Fields:    Translation:Humans
    78. A short version of Mini-Mental State Examination (MMSE) was as accurate as the original MMSE for predicting dementia. Evid Based Med. 2007 Oct; 12(5):150. Hirsch C. PMID: 17909241.
      View in: PubMed   Mentions: 1     Fields:    
    79. An exercise program led to a slower decline in activities of daily living in nursing-home patients with Alzheimer disease. ACP J Club. 2007 Jul-Aug; 147(1):5. Hirsch C. PMID: 17608370.
      View in: PubMed   Mentions:    Fields:    
    80. Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation. 2007 Jul 03; 116(1):32-8. Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M. PMID: 17576871.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansPHPublic Health
    81. Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study. Arch Intern Med. 2007 Apr 09; 167(7):635-41. Barzilay JI, Blaum C, Moore T, Xue QL, Hirsch CH, Walston JD, Fried LP. PMID: 17420420.
      View in: PubMed   Mentions: 182     Fields:    Translation:Humans
    82. Community based occupational therapy improved daily functioning in older patients with dementia. Evid Based Med. 2007 Apr; 12(2):51. Hirsch C. PMID: 17400643.
      View in: PubMed   Mentions: 2     Fields:    
    83. Community-based occupational therapy improved daily functioning in older patients with dementia. ACP J Club. 2007 Mar-Apr; 146(2):34. Hirsch C. PMID: 17335157.
      View in: PubMed   Mentions: 1     Fields:    
    84. Inflammation biomarkers and near-term death in older men. Am J Epidemiol. 2007 Mar 15; 165(6):684-95. Jenny NS, Yanez ND, Psaty BM, Kuller LH, Hirsch CH, Tracy RP. PMID: 17215383.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansPHPublic Health
    85. Galantamine was effective in mild-to-moderate Alzheimer disease. ACP J Club. 2006 Sep-Oct; 145(2):50. Hirsch C. PMID: 16944870.
      View in: PubMed   Mentions:    Fields:    
    86. The association of alcohol consumption and incident heart failure: the Cardiovascular Health Study. J Am Coll Cardiol. 2006 Jul 18; 48(2):305-11. Bryson CL, Mukamal KJ, Mittleman MA, Fried LP, Hirsch CH, Kitzman DW, Siscovick DS. PMID: 16843180.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    87. Review: atypical antipsychotic drugs increase risk for death in dementia. ACP J Club. 2006 Mar-Apr; 144(2):36. Hirsch C. PMID: 16539351.
      View in: PubMed   Mentions: 1     Fields:    
    88. The association of race with frailty: the cardiovascular health study. Ann Epidemiol. 2006 Jul; 16(7):545-53. Hirsch C, Anderson ML, Newman A, Kop W, Jackson S, Gottdiener J, Tracy R, Fried LP, Cardiovascular Health Study Research Group. PMID: 16388967.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    89. Kidney function as a predictor of noncardiovascular mortality. J Am Soc Nephrol. 2005 Dec; 16(12):3728-35. Fried LF, Katz R, Sarnak MJ, Shlipak MG, Chaves PH, Jenny NS, Stehman-Breen C, Gillen D, Bleyer AJ, Hirsch C, Siscovick D, Newman AB. PMID: 16251239.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    90. A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health Study. Arch Intern Med. 2005 Oct 24; 165(19):2214-20. Zakai NA, Katz R, Hirsch C, Shlipak MG, Chaves PH, Newman AB, Cushman M. PMID: 16246985.
      View in: PubMed   Mentions: 151     Fields:    Translation:Humans
    91. Review: limited evidence supports the use of atypical antipsychotic drugs in behavioral and psychological symptoms of dementia. ACP J Club. 2005 Jan-Feb; 142(1):15. Hirsch C. PMID: 15656556.
      View in: PubMed   Mentions:    Fields:    
    92. Review: pharmacotherapy improves cognitive symptoms in dementia. ACP J Club. 2005 Jan-Feb; 142(1):14. Hirsch C. PMID: 15656555.
      View in: PubMed   Mentions:    Fields:    
    93. Associates of bone mineral density in older African Americans. J Natl Med Assoc. 2004 Dec; 96(12):1609-15. Robbins J, Hirsch C, Cauley J. PMID: 15622691; PMCID: PMC2568675.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    94. Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. Stroke. 2005 Jan; 36(1):56-61. Longstreth WT, Arnold AM, Beauchamp NJ, Manolio TA, Lefkowitz D, Jungreis C, Hirsch CH, O'Leary DH, Furberg CD. PMID: 15569873.
      View in: PubMed   Mentions: 180     Fields:    Translation:Humans
    95. Memantine was better than placebo in Alzheimer disease already being treated with donepezil. ACP J Club. 2004 Sep-Oct; 141(2):38. Hirsch CH. PMID: 15341458.
      View in: PubMed   Mentions: 1     Fields:    
    96. Cognitive stimulation therapy improved cognition and quality of life in dementia. Evidence-Based Medicine. 2004 Mar 1; 9(2):49. Hirsch HC. .
      View in: Publisher Site   Mentions:
    97. "Successful aging": effect of subclinical cardiovascular disease. Arch Intern Med. 2003 Oct 27; 163(19):2315-22. Newman AB, Arnold AM, Naydeck BL, Fried LP, Burke GL, Enright P, Gottdiener J, Hirsch C, O'Leary D, Tracy R, Cardiovascular Health Study Research Group. PMID: 14581251.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    98. Transitions in spousal caregiving. Gerontologist. 2003 Apr; 43(2):230-41. Burton LC, Zdaniuk B, Schulz R, Jackson S, Hirsch C. PMID: 12677080.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    99. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med. 2002 Nov 11; 162(20):2333-41. Walston J, McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, Gottdiener J, Fried LP, Cardiovascular Health Study. PMID: 12418947.
      View in: PubMed   Mentions: 346     Fields:    Translation:Humans
    100. A community support program for dementia delayed but did not reduce institutionalization over 2 years. ACP J Club. 2002 Mar-Apr; 136(2):60. Hirsch CH. PMID: 11874285.
      View in: PubMed   Mentions:    Fields:    
    101. Inflammation and coagulation factors in persons > 65 years of age with symptoms of depression but without evidence of myocardial ischemia. Am J Cardiol. 2002 Feb 15; 89(4):419-24. Kop WJ, Gottdiener JS, Tangen CM, Fried LP, McBurnie MA, Walston J, Newman A, Hirsch C, Tracy RP. PMID: 11835923.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    102. Correlates of peak expiratory flow lability in elderly persons. Chest. 2001 Dec; 120(6):1861-8. Enright PL, McClelland RL, Buist AS, Lebowitz MD, Cardiovascular Health Study Research Group. PMID: 11742914.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    103. Review: galantamine improves most outcomes in suspected Alzheimer's disease. Evidence-Based Mental Health. 2001 Aug 1; 4(3):85. Hirsch HC. .
      View in: Publisher Site   Mentions:
    104. Involvement in caregiving and adjustment to death of a spouse: findings from the caregiver health effects study. JAMA. 2001 Jun 27; 285(24):3123-9. Schulz R, Beach SR, Lind B, Martire LM, Zdaniuk B, Hirsch C, Jackson S, Burton L. PMID: 11427141.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    105. The association of bone mineral density and depression in an older population. J Am Geriatr Soc. 2001 Jun; 49(6):732-6. Robbins J, Hirsch C, Whitmer R, Whitmer R, Cauley J, Harris T. PMID: 11454111.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansPHPublic Health
    106. The management of elder mistreatment: the physician's role. Wien Klin Wochenschr. 2001 May 15; 113(10):384-92. Hirsch CH, Loewy R. PMID: 11432128.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    107. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001 Mar; 56(3):M146-56. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Cardiovascular Health Study Collaborative Research Group. PMID: 11253156.
      View in: PubMed   Mentions: 7263     Fields:    Translation:Humans
    108. Associations of subclinical cardiovascular disease with frailty. J Gerontol A Biol Sci Med Sci. 2001 Mar; 56(3):M158-66. Newman AB, Gottdiener JS, Mcburnie MA, Hirsch CH, Kop WJ, Tracy R, Walston JD, Fried LP, Cardiovascular Health Study Research Group. PMID: 11253157.
      View in: PubMed   Mentions: 293     Fields:    Translation:Humans
    109. The primary care of elder mistreatment. West J Med. 1999 Jun; 170(6):353-8. Hirsch CH, Stratton S, Loewy R. PMID: 10443164; PMCID: PMC1305693.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    110. Correlates of performance-based measures of muscle function in the elderly: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 1997 Jul; 52(4):M192-200. Hirsch CH, Fried LP, Harris T, Fitzpatrick A, Enright P, Schulz R. PMID: 9224430.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    111. Preventive health behaviors among spousal caregivers. Prev Med. 1997 Mar-Apr; 26(2):162-9. Burton LC, Newsom JT, Schulz R, Hirsch CH, German PS. PMID: 9085384.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    112. Health effects of caregiving: the caregiver health effects study: an ancillary study of the Cardiovascular Health Study. Ann Behav Med. 1997; 19(2):110-6. Schulz R, Newsom J, Mittelmark M, Burton L, Hirsch C, Jackson S. PMID: 9603685.
      View in: PubMed   Mentions: 120     Fields:    Translation:Humans
    113. When your patient needs surgery: how planning can avoid complications. Geriatrics. 1995 Feb; 50(2):39-44. Hirsch CH. PMID: 7835724.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    114. When your patient needs surgery: weighing risks versus benefits. Geriatrics. 1995 Jan; 50(1):26-31. Hirsch CH. PMID: 7821826.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    115. Predictors of perceived health status in elderly men and women. The Cardiovascular Health Study. J Aging Health. 1994 Nov; 6(4):419-47. Schulz R, Mittelmark M, Kronmal R, Polak JF, Hirsch CH, German P, Bookwala J. PMID: 10138383.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    116. Temporal patterns of antihypertensive medication use among elderly patients. The Cardiovascular Health Study. JAMA. 1993 Oct 20; 270(15):1837-41. Psaty BM, Savage PJ, Tell GS, Polak JF, Hirsch CH, Gardin JM, McDonald RH. PMID: 8105112.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    117. Effects of a nursing-home respite admission on veterans with advanced dementia. Gerontologist. 1993 Aug; 33(4):523-8. Hirsch CH, Davies HD, Boatwright F, Ochango G. PMID: 8375682.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    118. Clinic-based primary care of frail older patients in California. West J Med. 1992 Apr; 156(4):385-91. Hirsch CH, Winograd CH. PMID: 1574881; PMCID: PMC1003277.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    119. The natural history of functional morbidity in hospitalized older patients. J Am Geriatr Soc. 1990 Dec; 38(12):1296-303. Hirsch CH, Sommers L, Olsen A, Mullen L, Winograd CH. PMID: 2123911.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
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