Crystal M Ripplinger

TitleAsst Prof
InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ripplinger C. The best thing since sliced bread? Optical mapping of transverse cardiac slices in the mouse heart. J Physiol. 2018 Jul 04. PMID: 29974471.
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    2. Francis Stuart SD, Wang L, Woodard WR, Ng GA, Habecker BA, Ripplinger C. Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation. J Physiol. 2018 Jun 25. PMID: 29938794.
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    3. Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, Recchia FA, Schwartz Longacre L, Ripplinger C, Van Eyk JE, Heusch G. Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol. 2018 Apr 01; 314(4):H812-H838. PMID: 29351451.
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    4. Parrish DC, Francis Stuart SD, Olivas A, Wang L, Nykjaer A, Ripplinger C, Habecker BA. Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility. Am J Physiol Heart Circ Physiol. 2018 Mar 01; 314(3):H415-H423. PMID: 29101167.
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    5. Lang D, Sato D, Jiang Y, Ginsburg KS, Ripplinger C, Bers DM. Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart. Circ Res. 2017 Dec 08; 121(12):1379-1391. PMID: 28970285.
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    6. Ripplinger C. From drugs to devices and back again: chemical vagal nerve stimulation for the treatment of heart failure. Cardiovasc Res. 2017 Sep 01; 113(11):1270-1272. PMID: 28859301.
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    7. Murphy SR, Wang L, Wang Z, Domondon P, Lang D, Habecker BA, Myles RC, Ripplinger C. ß-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia. Front Physiol. 2017; 8:630. PMID: 28894423.
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    8. Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger C, Wolin MS. Why publish in the American Journal of Physiology-Heart and Circulatory Physiology? Am J Physiol Heart Circ Physiol. 2017 Aug 01; 313(2):H221-H223. PMID: 28626081.
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    9. De Jesus NM, Wang L, Lai J, Rigor RR, Francis Stuart SD, Bers DM, Lindsey ML, Ripplinger C. Antiarrhythmic effects of interleukin 1 inhibition after myocardial infarction. Heart Rhythm. 2017 05; 14(5):727-736. PMID: 28111350.
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    10. Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger C, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, Bers DM, Nerbonne JM. Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics. J Physiol. 2017 Apr 01; 595(7):2229-2252. PMID: 27808412.
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    11. Habecker BA, Anderson ME, Birren SJ, Fukuda K, Herring N, Hoover DB, Kanazawa H, Paterson DJ, Ripplinger C. Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease. J Physiol. 2016 07 15; 594(14):3853-75. PMID: 27060296; PMCID: PMC4945713 [Available on 07/15/17].
    12. Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger C, Hammock BD, Chiamvimonvat N. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). PMID: 27162031; PMCID: PMC4869994 [Available on 05/01/17].
    13. Gardner RT, Ripplinger C, Myles RC, Habecker BA. Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias. Circ Arrhythm Electrophysiol. 2016 Feb; 9(2):e001359. PMID: 26810594; PMCID: PMC4730917 [Available on 02/01/17].
    14. Olivas A, Gardner RT, Wang L, Ripplinger C, Woodward WR, Habecker BA. Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130. J Neurosci. 2016 Jan 13; 36(2):479-88. PMID: 26758839; PMCID: PMC4710771.
    15. Ripplinger C, Noujaim SF, Linz D. The nervous heart. Prog Biophys Mol Biol. 2016 Jan; 120(1-3):199-209. PMID: 26780507; PMCID: PMC4808395 [Available on 01/11/17].
    16. Quinn TA, Ripplinger C. Recent developments in biophysics & molecular biology of heart rhythm. Prog Biophys Mol Biol. 2016 Jan; 120(1-3):1-2. PMID: 26777585.
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    17. Francis Stuart SD, De Jesus NM, Lindsey ML, Ripplinger C. The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction. J Mol Cell Cardiol. 2016 Feb; 91:114-22. PMID: 26739214; PMCID: PMC4764395 [Available on 02/01/17].
    18. Wang L, De Jesus NM, Ripplinger C. Optical Mapping of Intra-Sarcoplasmic Reticulum Ca2+ and Transmembrane Potential in the Langendorff-perfused Rabbit Heart. J Vis Exp. 2015 Sep 10; (103). PMID: 26382577; PMCID: PMC4676338.
    19. Bartos DC, Grandi E, Ripplinger C. Ion Channels in the Heart. Compr Physiol. 2015 Jul 01; 5(3):1423-64. PMID: 26140724; PMCID: PMC4516287.
    20. Ripplinger C, Efimov IR. Dual Vm/Ca imaging of premature ventricular contractions: bridging the gap of anatomical scales. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):529-30. PMID: 26082526; PMCID: PMC4617379.
    21. Hammer KP, Ljubojevic S, Ripplinger C, Pieske BM, Bers DM. Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and ß-adrenergic stimulation. J Mol Cell Cardiol. 2015 Jul; 84:1-9. PMID: 25828762; PMCID: PMC4500534.
    22. Ripplinger C. A leap(frog) forward in understanding focal arrhythmia. J Physiol. 2015 Mar 15; 593(6):1383-4. PMID: 25772292; PMCID: PMC4376417.
    23. Ripplinger C. Mouse models of cardiac conduction system markers: revealing the past, present, and future of pacemaking and conduction. Trends Cardiovasc Med. 2015 Jan; 25(1):10-1. PMID: 25446050.
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    24. De Jesus NM, Wang L, Herren AW, Wang J, Shenasa F, Bers DM, Lindsey ML, Ripplinger C. Atherosclerosis exacerbates arrhythmia following myocardial infarction: Role of myocardial inflammation. Heart Rhythm. 2015 Jan; 12(1):169-78. PMID: 25304682; PMCID: PMC4277908.
    25. Myles RC, Wang L, Bers DM, Ripplinger C. Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart. J Physiol. 2015 Mar 15; 593(6):1479-93. PMID: 25772297; PMCID: PMC4376425.
    26. DeLeon-Pennell KY, de Castro Brás LE, Iyer RP, Bratton DR, Jin YF, Ripplinger C, Lindsey ML. P. gingivalis lipopolysaccharide intensifies inflammation post-myocardial infarction through matrix metalloproteinase-9. J Mol Cell Cardiol. 2014 Nov; 76:218-26. PMID: 25240641; PMCID: PMC4250428.
    27. Wang L, Myles RC, De Jesus NM, Ohlendorf AK, Bers DM, Ripplinger C. Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation. Circ Res. 2014 Apr 25; 114(9):1410-21. PMID: 24568740; PMCID: PMC4000583.
    28. Feinberg AW, Ripplinger C, van der Meer P, Sheehy SP, Domian I, Chien KR, Parker KK. Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes. Stem Cell Reports. 2013; 1(5):387-96. PMID: 24286027; PMCID: PMC3841251.
    29. Erickson JR, Pereira L, Wang L, Han G, Ferguson A, Dao K, Copeland RJ, Despa F, Hart GW, Ripplinger C, Bers DM. Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature. 2013 Oct 17; 502(7471):372-6. PMID: 24077098; PMCID: PMC3801227.
    30. Ripplinger C, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA. Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2616-24. PMID: 22995524; PMCID: PMC3516622.
    31. Nawroth JC, Lee H, Feinberg AW, Ripplinger C, McCain ML, Grosberg A, Dabiri JO, Parker KK. A tissue-engineered jellyfish with biomimetic propulsion. Nat Biotechnol. 2012 Aug; 30(8):792-7. PMID: 22820316; PMCID: PMC4026938.
    32. Sondergaard CS, Mathews G, Wang L, Jeffreys A, Sahota A, Wood M, Ripplinger C, Si MS. Contractile and electrophysiologic characterization of optimized self-organizing engineered heart tissue. Ann Thorac Surg. 2012 Oct; 94(4):1241-8; discussion 1249. PMID: 22795054; PMCID: PMC4075435.
    33. Feinberg AW, Alford PW, Jin H, Ripplinger C, Werdich AA, Sheehy SP, Grosberg A, Parker KK. Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture. Biomaterials. 2012 Aug; 33(23):5732-41. PMID: 22594976; PMCID: PMC4026933.
    34. Myles RC, Wang L, Kang C, Bers DM, Ripplinger C. Local ß-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia. Circ Res. 2012 May 25; 110(11):1454-64. PMID: 22539768; PMCID: PMC3396564.
    35. Ripplinger C, Bers DM. Human biological pacemakers: intrinsic variability and stability. Circulation. 2012 Feb 21; 125(7):856-8. PMID: 22261197.
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    36. Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger C, Kass RS, Clancy CE. A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Sci Transl Med. 2011 Aug 31; 3(98):98ra83. PMID: 21885405; PMCID: PMC3328405.
    37. Ambrosi CM, Ripplinger C, Efimov IR, Fedorov VV. Termination of sustained atrial flutter and fibrillation using low-voltage multiple-shock therapy. Heart Rhythm. 2011 Jan; 8(1):101-8. PMID: 20969974; PMCID: PMC3384750.
    38. Li W, Ripplinger C, Lou Q, Efimov IR. Multiple monophasic shocks improve electrotherapy of ventricular tachycardia in a rabbit model of chronic infarction. Heart Rhythm. 2009 Jul; 6(7):1020-7. PMID: 19560090; PMCID: PMC2813769.
    39. Lombardi R, Rodriguez G, Chen SN, Ripplinger C, Li W, Chen J, Willerson JT, Betocchi S, Wickline SA, Efimov IR, Marian AJ. Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation. 2009 Mar 17; 119(10):1398-407. PMID: 19255346; PMCID: PMC2773801.
    40. Ripplinger C, Lou Q, Li W, Hadley J, Efimov IR. Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion. Heart Rhythm. 2009 Jan; 6(1):87-97. PMID: 18996057; PMCID: PMC2650268.
    41. Hucker WJ, Ripplinger C, Fleming CP, Fedorov VV, Rollins AM, Efimov IR. Bimodal biophotonic imaging of the structure-function relationship in cardiac tissue. J Biomed Opt. 2008 Sep-Oct; 13(5):054012. PMID: 19021392; PMCID: PMC2719892.
    42. Lou Q, Ripplinger C, Bayly PV, Efimov IR. Quantitative panoramic imaging of epicardial electrical activity. Ann Biomed Eng. 2008 Oct; 36(10):1649-58. PMID: 18654852; PMCID: PMC2714651.
    43. Fleming CP, Ripplinger C, Webb B, Efimov IR, Rollins AM. Quantification of cardiac fiber orientation using optical coherence tomography. J Biomed Opt. 2008 May-Jun; 13(3):030505. PMID: 18601522; PMCID: PMC2714642.
    44. Ripplinger C, Li W, Hadley J, Chen J, Rothenberg F, Lombardi R, Wickline SA, Marian AJ, Efimov IR. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ Res. 2007 Nov 09; 101(10):1049-57. PMID: 17885214; PMCID: PMC2366809.
    45. Qu F, Ripplinger C, Nikolski VP, Grimm C, Efimov IR. Three-dimensional panoramic imaging of cardiac arrhythmias in rabbit heart. J Biomed Opt. 2007 Jul-Aug; 12(4):044019. PMID: 17867823.
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    46. Ahlberg SE, Ripplinger C, Skadsberg ND, Iaizzo PA, Mulligan LJ. Effects of pacing rate on mechanical restitution within the in vivo canine heart: study of the force-frequency relationship. J Cardiovasc Electrophysiol. 2007 Feb; 18(2):212-7. PMID: 17239141.
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    47. Efimov I, Ripplinger C. Virtual electrode hypothesis of defibrillation. Heart Rhythm. 2006 Sep; 3(9):1100-2. PMID: 16945810.
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    48. Ripplinger C, Krinsky VI, Nikolski VP, Efimov IR. Mechanisms of unpinning and termination of ventricular tachycardia. Am J Physiol Heart Circ Physiol. 2006 Jul; 291(1):H184-92. PMID: 16501014.
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    49. Efimov IR, Ripplinger C. Tornado in a dish: revealing the mechanisms of ventricular arrhythmias in engineered cardiac tissues. Cardiovasc Res. 2006 Feb 01; 69(2):307-8. PMID: 16325163.
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    50. Byrd GD, Prasad SM, Ripplinger C, Cassilly TR, Schuessler RB, Boineau JP, Damiano RJ. Importance of geometry and refractory period in sustaining atrial fibrillation: testing the critical mass hypothesis. Circulation. 2005 Aug 30; 112(9 Suppl):I7-13. PMID: 16159868.
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