Dake Hao

Title(s)Assistant Professor, Med: Surgery
SchoolSchool of Medicine
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    Title(s)Assistant Professor in Residence, Med: Surgery


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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. FTO-mediated m6A demethylation of SERPINE1 mRNA promotes tumor progression in hypopharyngeal squamous cell carcinoma. Transl Cancer Res. 2025 Jan 31; 14(1):595-612. Sa N, Liu X, Hao D, Lv Z, Zhou S, Yang L, Jiang S, Tian J, Xu W. PMID: 39974406; PMCID: PMC11833370.
      View in: PubMed   Mentions: 2  
    2. Post-death Vesicles of Senescent Bone Marrow Mesenchymal Stromal Polyploids Promote Macrophage Aging and Breast Cancer. bioRxiv. 2024 Mar 08. Xie B, Fan M, Wang CX, Zhang Y, Xu S, Mizenko R, Lin TY, Duan Y, Zhang Y, Huang J, Berg JI, Wu D, Li A, Hao D, Gao K, Sun Y, Tepper CG, Carney R, Li Y, Wang A, Gong Q, Daly M, Jao LE, Monjazeb AM, Fierro FA, Li JJ. PMID: 38496556; PMCID: PMC10942423.
      View in: PubMed   Mentions:
    3. Development of pro-angiogenic skin substitutes for wound healing. Wound Repair Regen. 2024 May-Jun; 32(3):208-216. Song H, Hao D, Zhou J, Farmer D, Wang A. PMID: 38308588.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    4. A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. Bioact Mater. 2023 Oct; 28:467-479. Hao D, Lin J, Liu R, Pivetti C, Yamashiro K, Schutzman LM, Sageshima J, Kwong M, Bahatyrevich N, Farmer DL, Humphries MD, Lam KS, Panitch A, Wang A. PMID: 37408799; PMCID: PMC10318457.
      View in: PubMed   Mentions: 2  
    5. Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. Front Pharmacol. 2023; 14:1125209. Song H, Gao K, Hao D, Li A, Liu R, Anggito B, Yin B, Jin Q, Dartora V, Lam KS, Smith LR, Panitch A, Zhou J, Farmer DL, Wang A. PMID: 36937891; PMCID: PMC10014525.
      View in: PubMed   Mentions: 3  
    6. Evaluation of a biodegradable polyurethane patch for repair of diaphragmatic hernia in a rat model: A pilot study. J Pediatr Surg. 2023 May; 58(5):964-970. Theodorou CM, Taylor A, Lee SY, Cortez LM, Fu H, Pivetti CD, Zhang C, Stasyuk A, Hao D, Kumar P, Farmer DL, Liao J, Brown EG, Hong Y, Wang A. PMID: 36797111; PMCID: PMC10184880.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. Theranostics. 2022; 12(13):6021-6037. Hao D, Lu L, Song H, Duan Y, Chen J, Carney R, Li JJ, Zhou P, Nolta J, Lam KS, Leach JK, Farmer DL, Panitch A, Wang A. PMID: 35966577; PMCID: PMC9373818.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    8. Bioengineering Extracellular Vesicles for the Treatment of Cardiovascular Diseases. Adv Biol (Weinh). 2022 10; 6(10):e2200087. Ramasubramanian L, Du S, Gidda S, Bahatyrevich N, Hao D, Kumar P, Wang A. PMID: 35778828; PMCID: PMC9588622.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    9. A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. Bioact Mater. 2023 Feb; 20:179-193. Hao D, Liu R, Fernandez TG, Pivetti C, Jackson JE, Kulubya ES, Jiang HJ, Ju HY, Liu WL, Panitch A, Lam KS, Leach JK, Farmer DL, Wang A. PMID: 35663336; PMCID: PMC9160290.
      View in: PubMed   Mentions: 11  
    10. Engineering Extracellular Microenvironment for Tissue Regeneration. Bioengineering (Basel). 2022 May 08; 9(5). Hao D, Lopez JM, Chen J, Iavorovschi AM, Lelivelt NM, Wang A. PMID: 35621480; PMCID: PMC9137730.
      View in: PubMed   Mentions: 10  
    11. A bioactive compliant vascular graft modulates macrophage polarization and maintains patency with robust vascular remodeling. Bioact Mater. 2023 Jan; 19:167-178. Stahl A, Hao D, Barrera J, Henn D, Lin S, Moeinzadeh S, Kim S, Maloney W, Gurtner G, Wang A, Yang YP. PMID: 35510174; PMCID: PMC9034314.
      View in: PubMed   Mentions: 15  
    12. The Unique Properties of Placental Mesenchymal Stromal Cells: A Novel Source of Therapy for Congenital and Acquired Spinal Cord Injury. Cells. 2021 10 22; 10(11). Kulubya ES, Clark K, Hao D, Lazar S, Ghaffari-Rafi A, Karnati T, Ebinu JO, Zwienenberg M, Farmer DL, Wang A. PMID: 34831060; PMCID: PMC8616037.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    13. Engineering extracellular vesicles for Alzheimer's disease: An emerging cell-free approach for earlier diagnosis and treatment. WIREs Mech Dis. 2022 03; 14(2):e1541. Lazar SV, Mor S, Wang D, Goldbloom-Helzner L, Clark K, Hao D, Farmer DL, Wang A. PMID: 35266650; PMCID: PMC9397584.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing. Bioact Mater. 2022 Apr; 10:460-473. He S, Walimbe T, Chen H, Gao K, Kumar P, Wei Y, Hao D, Liu R, Farmer DL, Lam KS, Zhou J, Panitch A, Wang A. PMID: 34901560; PMCID: PMC8636679.
      View in: PubMed   Mentions: 24  
    15. Nrf2 Regulates CHI3L1 to Suppress Inflammation and Improve Post-Traumatic Osteoarthritis. J Inflamm Res. 2021; 14:4079-4088. Song Y, Hao D, Jiang H, Huang M, Du Q, Lin Y, Liu F, Chen B. PMID: 34466014; PMCID: PMC8403022.
      View in: PubMed   Mentions: 16  
    16. Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection. World J Stem Cells. 2021 Jul 26; 13(7):776-794. Nasirishargh A, Kumar P, Ramasubramanian L, Clark K, Hao D, Lazar SV, Wang A. PMID: 34367477; PMCID: PMC8316862.
      View in: PubMed   Mentions: 26  
    17. Bioengineered extracellular vesicle-loaded bioscaffolds for therapeutic applications in regenerative medicine. Extracell Vesicles Circ Nucl Acids. 2021; 2:175-178. Lazar S, Mor S, Chen J, Hao D, Wang A. PMID: 34622248; PMCID: PMC8494210.
      View in: PubMed   Mentions: 14  
    18. Long non-coding RNA signatures as predictors of prognosis in thyroid cancer: a narrative review. Ann Transl Med. 2021 Feb; 9(4):359. Zhao H, De Souza C, Kumar VE, Nambiar R, Hao D, Zhu X, Luo Y, Liu S, Zhang L, Zhu J. PMID: 33708986; PMCID: PMC7944284.
      View in: PubMed   Mentions: 5  
    19. Developing an Injectable Nanofibrous Extracellular Matrix Hydrogel With an Integrin αvβ3 Ligand to Improve Endothelial Cell Survival, Engraftment and Vascularization. Front Bioeng Biotechnol. 2020; 8:890. Hao D, Liu R, Gao K, He C, He S, Zhao C, Sun G, Farmer DL, Panitch A, Lam KS, Wang A. PMID: 32850742; PMCID: PMC7403189.
      View in: PubMed   Mentions: 8  
    20. Extracellular Matrix Mimicking Nanofibrous Scaffolds Modified With Mesenchymal Stem Cell-Derived Extracellular Vesicles for Improved Vascularization. Front Bioeng Biotechnol. 2020; 8:633. Hao D, Swindell HS, Ramasubramanian L, Liu R, Lam KS, Farmer DL, Wang A. PMID: 32671037; PMCID: PMC7329993.
      View in: PubMed   Mentions: 38  
    21. Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomater. 2020 05; 108:178-193. Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. PMID: 32151698; PMCID: PMC8012081.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    22. Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved the adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new insight for fetal tissue engineering. J Mater Chem B. 2020 02 26; 8(8):1649-1659. Hao D, Ma B, He C, Liu R, Farmer DL, Lam KS, Wang A. PMID: 32011618; PMCID: PMC7353926.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    23. Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. Stem Cells Int. 2019; 2019:9695239. Hao D, He C, Ma B, Lankford L, Reynaga L, Farmer DL, Guo F, Wang A. PMID: 31781252; PMCID: PMC6874947.
      View in: PubMed   Mentions: 22  
    24. Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. Int J Mol Sci. 2019 Aug 21; 20(17). Goldbloom-Helzner L, Hao D, Wang A. PMID: 31438477; PMCID: PMC6747276.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    25. The functions and applications of A7R in anti-angiogenic therapy, imaging and drug delivery systems. Asian J Pharm Sci. 2019 Nov; 14(6):595-608. Lu L, Chen H, Hao D, Zhang X, Wang F. PMID: 32104486; PMCID: PMC7032227.
      View in: PubMed   Mentions: 14  
    26. A Novel lncRNA IHS Promotes Tumor Proliferation and Metastasis in HCC by Regulating the ERK- and AKT/GSK-3β-Signaling Pathways. Mol Ther Nucleic Acids. 2019 Jun 07; 16:707-720. Chen Z, Yu W, Zhou Q, Zhang J, Jiang H, Hao D, Wang J, Zhou Z, He C, Xiao Z. PMID: 31128422; PMCID: PMC6535504.
      View in: PubMed   Mentions: 36  
    27. Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells. Stem Cell Res Ther. 2019 01 22; 10(1):34. Gao K, Kumar P, Cortez-Toledo E, Hao D, Reynaga L, Rose M, Wang C, Farmer D, Nolta J, Zhou J, Zhou P, Wang A. PMID: 30670078; PMCID: PMC6341603.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    28. ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma. J Exp Clin Cancer Res. 2019 Jan 15; 38(1):18. Zhou Z, Jiang H, Tu K, Yu W, Zhang J, Hu Z, Zhang H, Hao D, Huang P, Wang J, Wang A, Xiao Z, He C. PMID: 30646949; PMCID: PMC6332640.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    29. Engineering mesenchymal stem cells to improve their exosome efficacy and yield for cell-free therapy. J Extracell Vesicles. 2018; 7(1):1522236. Phan J, Kumar P, Hao D, Gao K, Farmer D, Wang A. PMID: 30275938; PMCID: PMC6161586.
      View in: PubMed   Mentions: 177     Fields:    
    30. Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 04 21; 12(4):1075-1086. Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. PMID: 28195700; PMCID: PMC5875449.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    31. Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways. Stem Cells. 2017 04; 35(4):909-919. Harding A, Cortez-Toledo E, Magner NL, Beegle JR, Coleal-Bergum DP, Hao D, Wang A, Nolta JA, Zhou P. PMID: 28248004.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
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