David Asmuth

Title(s)Clinical Professor, Infectious Diseases
SchoolUniversity of California, Davis
AddressPSSB/UCDMC
CA 95817
Phone916-734-8695
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    Collapse Research 
    Collapse Research Activities and Funding
    Multicolor Flow Users Network Study
    NIH R01AI051999Jul 1, 2002 - Jun 30, 2006
    Role: Principal Investigator
    VIRAL LOAD IN CELLULAR SUBCOMPARTMENTS FOLLOWING HAART
    NIH K23AI001688Jun 3, 1999 - Feb 28, 2005
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Women are from venus: implications for diversified sex-based preexposure prophylaxis approaches. AIDS. 2021 08 01; 35(10):1691-1693. Marchetti G, Asmuth D. PMID: 34270492.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    2. Long-term safety and efficacy of emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV-1 pre-exposure prophylaxis: week 96 results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet HIV. 2021 07; 8(7):e397-e407. Ogbuagu O, Ruane PJ, Podzamczer D, Salazar LC, Henry K, Asmuth DM, Wohl D, Gilson R, Shao Y, Ebrahimi R, Cox S, Kintu A, Carter C, Das M, Baeten JM, Brainard DM, Whitlock G, Brunetta JM, Kronborg G, Spinner CD, DISCOVER study team. PMID: 34197772.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    3. Potential use of serum-derived bovine immunoglobulin/protein isolate for the management of COVID-19. Drug Dev Res. 2021 11; 82(7):873-879. Utay NS, Asmuth DM, Gharakhanian S, Contreras M, Warner CD, Detzel CJ. PMID: 34110032.
      View in: PubMed   Mentions:    Fields:    
    4. HIV/HCV therapy with ledipasvir/sofosbuvir after randomized switch to emtricitabine-tenofovir alafenamide-based single-tablet regimens. PLoS One. 2020; 15(1):e0224875. Huhn GD, Ramgopal M, Jain MK, Hinestrosa F, Asmuth DM, Slim J, Goldstein D, Applin S, Ryu JH, Jiang S, Cox S, Das M, Nguyen-Cleary T, Piontkowsky D, Guyer B, Rossaro L, Haubrich RH. PMID: 31995556; PMCID: PMC6988963.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Delayed gastrointestinal-associated lymphoid tissue reconstitution in duodenum compared with rectum in HIV-infected patients initiating antiretroviral therapy. AIDS. 2019 12 01; 33(15):2289-2298. Sainz T, Serrano-Villar S, Mann S, Ma ZM, Utay NS, Thompson CG, Chun TW, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Moreno S, Pollard RB, Landay A, Miller CJ, Asmuth DM. PMID: 31764094; PMCID: PMC6905119.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    6. Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART. Pathog Immun. 2019; 4(1):124-146. Utay NS, Somasunderam A, Hinkle JE, Petschow BW, Detzel CJ, Somsouk M, Fichtenbaum CJ, Weaver EM, Shaw AL, Asmuth DM. PMID: 31139758; PMCID: PMC6508431.
      View in: PubMed   Mentions: 4  
    7. Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption. PLoS One. 2019; 14(1):e0210965. Rockstroh JK, Asmuth D, Pantaleo G, Clotet B, Podzamczer D, van Lunzen J, Arastéh K, Mitsuyasu R, Peters B, Silvia N, Jolliffe D, Ökvist M, Krogsgaard K, Sommerfelt MA. PMID: 30699178; PMCID: PMC6353572.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    8. Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial. Clin Nutr. 2019 06; 38(3):1303-1309. Shivakoti R, Ewald ER, Gupte N, Yang WT, Kanyama C, Cardoso SW, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo U, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Pollard R, Detrick B, Balagopal A, Asmuth DM, Semba RD, Campbell TB, Golub J, Gupta A, NWCS 319 and ACTG PEARLS Study Team. PMID: 29885777; PMCID: PMC6265110.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. Associations of Plasma Cytokine and Microbial Translocation Biomarkers With Immune Reconstitution Inflammatory Syndrome. J Infect Dis. 2017 11 27; 216(9):1159-1163. George V, Harrison L, Roach M, Li XD, Tierney C, Fischl MA, Aberg J, Tebas P, Asmuth DM, Pollard RB, Godfrey C, Pahwa S, AIDS Clinical Trials Group A5202 Study Team. PMID: 29040604; PMCID: PMC5853564.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Evaluation of oral serum-derived bovine immunoglobulins in HIV-infected patients with chronic idiopathic diarrhea. HIV Clin Trials. 2017 Nov-Dec; 18(5-6):205-213. Asmuth DM, Hinkle JE, LaMarca A, Fichtenbaum CJ, Somsouk M, Utay NS, Shaw AL, Petschow BW, Detzel CJ, Weaver EM. PMID: 29210625.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    11. Tissue Pharmacologic and Virologic Determinants of Duodenal and Rectal Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution in HIV-Infected Patients Initiating Antiretroviral Therapy. J Infect Dis. 2017 10 17; 216(7):813-818. Asmuth DM, Thompson CG, Chun TW, Ma ZM, Mann S, Sainz T, Serrano-Villar S, Utay NS, Garcia JC, Troia-Cancio P, Pollard RB, Miller CJ, Landay A, Kashuba AD. PMID: 28968888; PMCID: PMC6279130.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Raltegravir 1200 mg once daily versus raltegravir 400 mg twice daily, with tenofovir disoproxil fumarate and emtricitabine, for previously untreated HIV-1 infection: a randomised, double-blind, parallel-group, phase 3, non-inferiority trial. Lancet HIV. 2017 11; 4(11):e486-e494. Cahn P, Kaplan R, Sax PE, Squires K, Molina JM, Avihingsanon A, Ratanasuwan W, Rojas E, Rassool M, Bloch M, Vandekerckhove L, Ruane P, Yazdanpanah Y, Katlama C, Xu X, Rodgers A, East L, Wenning L, Rawlins S, Homony B, Sklar P, Nguyen BY, Leavitt R, Teppler H, ONCEMRK Study Group. PMID: 28918877.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    13. Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2017 May; 13(5):e1006368. Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 28467485; PMCID: PMC5415081.
      View in: PubMed   Mentions:    Fields:    
    14. Hepatic safety of maraviroc in patients with HIV-1 and hepatitis C and/or B virus: 144-week results from a randomized, placebo-controlled trial. Antivir Ther. 2017; 22(3):263-269. Rockstroh JK, Plonski F, Bansal M, Fätkenheuer G, Small CB, Asmuth DM, Pialoux G, Zhang-Roper R, Wang R, Pineda JA, Heera J. PMID: 27924779.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    15. Sex-Related Differences in Inflammatory and Immune Activation Markers Before and After Combined Antiretroviral Therapy Initiation. J Acquir Immune Defic Syndr. 2016 10 01; 73(2):123-9. Mathad JS, Gupte N, Balagopal A, Asmuth D, Hakim J, Santos B, Riviere C, Hosseinipour M, Sugandhavesa P, Infante R, Pillay S, Cardoso SW, Mwelase N, Pawar J, Berendes S, Kumarasamy N, Andrade BB, Campbell TB, Currier JS, Cohn SE, Gupta A, New Work Concept Sheet 319 and AIDS Clinical Trials Group A5175 (PEARLS) Study Teams. PMID: 27258230; PMCID: PMC5023467.
      View in: PubMed   Mentions: 18  Translation:Humans
    16. Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort. Open Forum Infect Dis. 2016 Sep; 3(3):ofw118. Balagopal A, Gupte N, Shivakoti R, Cox AL, Yang WT, Berendes S, Mwelase N, Kanyama C, Pillay S, Samaneka W, Santos B, Poongulali S, Tripathy S, Riviere C, Lama JR, Cardoso SW, Sugandhavesa P, Semba RD, Hakim J, Hosseinipour MC, Kumarasamy N, Sanne I, Asmuth D, Campbell T, Bollinger RC, Gupta A. PMID: 27800521; PMCID: PMC5084713.
      View in: PubMed   Mentions: 7  
    17. Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Acquir Immune Defic Syndr. 2016 May 01; 72(1):31-8. Jacobson JM, Routy JP, Welles S, DeBenedette M, Tcherepanova I, Angel JB, Asmuth DM, Stein DK, Baril JG, McKellar M, Margolis DM, Trottier B, Wood K, Nicolette C. PMID: 26751016; PMCID: PMC4836975.
      View in: PubMed   Mentions: 24  Translation:HumansCellsCTClinical Trials
    18. Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Mar; 12(3):e1005540. Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 27015639; PMCID: PMC4807777.
      View in: PubMed   Mentions: 5     Fields:    
    19. Inflammation and Change in Body Weight With Antiretroviral Therapy Initiation in a Multinational Cohort of HIV-Infected Adults. J Infect Dis. 2016 Jul 01; 214(1):65-72. Mave V, Erlandson KM, Gupte N, Balagopal A, Asmuth DM, Campbell TB, Smeaton L, Kumarasamy N, Hakim J, Santos B, Riviere C, Hosseinipour MC, Sugandhavesa P, Infante R, Pillay S, Cardoso SW, Tripathy S, Mwelase N, Berendes S, Andrade BB, Thomas DL, Bollinger RC, Gupta A, ACTG PEARLS and NWCS 319 Study Team. PMID: 26962236; PMCID: PMC4907416.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    20. Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Jan; 12(1):e1005381. Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 26795282; PMCID: PMC4721954.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    21. Peginterferon α-2a for the treatment of HIV infection. Expert Opin Investig Drugs. 2016; 25(2):249-57. Asmuth DM, Utay NS, Pollard RB. PMID: 26667398.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    22. Corrigendum. Hepatic Safety in Subjects With HIV-1 and Hepatitis C and/or B Virus: A Randomised, Double-Blind Study of Maraviroc vs Placebo in Combination With Antiretroviral Agents. HIV Clin Trials. 2015 Nov; 16(6):236-7. Rockstroch JK, Soriano V, Plonski F, Bansal M, Fätkenheuer G, Small CB, Asmuth DM, Pialoux G, Mukwaya G, Jagannatha S, Heera J, Pineda JA. PMID: 26777796.
      View in: PubMed   Mentions:    Fields:    
    23. Pre-cART Elevation of CRP and CD4+ T-Cell Immune Activation Associated With HIV Clinical Progression in a Multinational Case-Cohort Study. J Acquir Immune Defic Syndr. 2015 Oct 01; 70(2):163-71. Balagopal A, Asmuth DM, Yang WT, Campbell TB, Gupte N, Smeaton L, Kanyama C, Grinsztejn B, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo UG, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Li XD, Pollard RB, Semba RD, Thomas DL, Bollinger RC, Gupta A, ACTG PEARLS and NWCS 319 Study team. PMID: 26017661; PMCID: PMC4573329.
      View in: PubMed   Mentions: 12  Translation:HumansCells
    24. Role of intestinal myofibroblasts in HIV-associated intestinal collagen deposition and immune reconstitution following combination antiretroviral therapy. AIDS. 2015 May 15; 29(8):877-88. Asmuth DM, Pinchuk IV, Wu J, Vargas G, Chen X, Mann S, Albanese A, Ma ZM, Saroufeem R, Melcher GP, Troia-Cancio P, Torok NJ, Miller CJ, Powell DW. PMID: 25784439; PMCID: PMC4520701.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    25. Hepatic safety in subjects with HIV-1 and hepatitis C and/or B virus: a randomized, double-blind study of maraviroc versus placebo in combination with antiretroviral agents. HIV Clin Trials. 2015 Mar-Apr; 16(2):72-80. Rockstroh JK, Soriano V, Plonski F, Bansal M, Fätkenheuer G, Small CB, Asmuth DM, Pialoux G, Mukwaya G, Jagannatha S, Heera J, Pineda JA. PMID: 25923596.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. C-reactive protein (CRP), interferon gamma-inducible protein 10 (IP-10), and lipopolysaccharide (LPS) are associated with risk of tuberculosis after initiation of antiretroviral therapy in resource-limited settings. PLoS One. 2015; 10(2):e0117424. Tenforde MW, Gupte N, Dowdy DW, Asmuth DM, Balagopal A, Pollard RB, Sugandhavesa P, Lama JR, Pillay S, Cardoso SW, Pawar J, Santos B, Riviere C, Mwelase N, Kanyama C, Kumwenda J, Hakim JG, Kumarasamy N, Bollinger R, Semba RD, Campbell TB, Gupta A, ACTG PEARLS and NWCS 319 Study Group. PMID: 25719208; PMCID: PMC4342263.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    27. Differential Specificity of Interferon-alpha Inducible Gene Expression in Association with Human Immunodeficiency Virus and Hepatitis C Virus Levels and Declines in vivo. J AIDS Clin Res. 2015; 6(1). Katsounas A, Frank AC, Lempicki RA, Polis MA, Asmuth DM, Kottilil S. PMID: 26052470; PMCID: PMC4456029.
      View in: PubMed   Mentions: 3  
    28. Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfection. JAMA. 2014 Jul 23-30; 312(4):353-61. Sulkowski MS, Naggie S, Lalezari J, Fessel WJ, Mounzer K, Shuhart M, Luetkemeyer AF, Asmuth D, Gaggar A, Ni L, Svarovskaia E, Brainard DM, Symonds WT, Subramanian GM, McHutchison JG, Rodriguez-Torres M, Dieterich D, PHOTON-1 Investigators. PMID: 25038354; PMCID: PMC4997358.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCellsCTClinical Trials
    29. Clinical and immunologic predictors of death after an acute opportunistic infection: results from ACTG A5164. HIV Clin Trials. 2014 Jul-Aug; 15(4):133-9. Grant PM, Komarow L, Sanchez A, Sattler FR, Asmuth DM, Pollard RB, Zolopa AR. PMID: 25143022; PMCID: PMC4167015.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Mucosal immunity in HIV infection: what can be done to restore gastrointestinal-associated lymphoid tissue function? Curr Opin Infect Dis. 2014 Jun; 27(3):275-81. George MD, Asmuth DM. PMID: 24739345.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    31. Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: a phase 2 randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2014 Apr; 14(4):291-300. Pollard RB, Rockstroh JK, Pantaleo G, Asmuth DM, Peters B, Lazzarin A, Garcia F, Ellefsen K, Podzamczer D, van Lunzen J, Arastéh K, Schürmann D, Clotet B, Hardy WD, Mitsuyasu R, Moyle G, Plettenberg A, Fisher M, Fätkenheuer G, Fischl M, Taiwo B, Baksaas I, Jolliffe D, Persson S, Jelmert O, Hovden AO, Sommerfelt MA, Wendel-Hansen V, Sørensen B. PMID: 24525316.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCellsCTClinical Trials
    32. Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIV-infected patients receiving combination antiretroviral therapy: results of the ACTG 5176 trial. J Acquir Immune Defic Syndr. 2013 Dec 01; 64(4):351-9. Rodriguez B, Asmuth DM, Matining RM, Spritzler J, Jacobson JM, Mailliard RB, Li XD, Martinez AI, Tenorio AR, Lori F, Lisziewicz J, Yesmin S, Rinaldo CR, Pollard RB. PMID: 24169120; PMCID: PMC3858388.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    33. Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy. AIDS. 2013 Sep 10; 27(14):2207-17. Asmuth DM, Ma ZM, Albanese A, Sandler NG, Devaraj S, Knight TH, Flynn NM, Yotter T, Garcia JC, Tsuchida E, Wu TT, Douek DC, Miller CJ. PMID: 23660579; PMCID: PMC3754419.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    34. Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa. AIDS. 2013 Mar 27; 27(6):867-877. Hayes TL, Asmuth DM, Critchfield JW, Knight TH, McLaughlin BE, Yotter T, McConnell DH, Garcia JC, Pollard RB, Shacklett BL. PMID: 23262500; PMCID: PMC4026034.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    35. HIV disease activity as a modulator of lipoprotein(a) and allele-specific apolipoprotein(a) levels. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):387-92. Enkhmaa B, Anuurad E, Zhang W, Abbuthalha A, Li XD, Dotterweich W, Pollard RB, Asmuth DM, Berglund L. PMID: 23202367; PMCID: PMC4537858.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    36. Short-term monotherapy with IDX184, a liver-targeted nucleotide polymerase inhibitor, in patients with chronic hepatitis C virus infection. Antimicrob Agents Chemother. 2012 Dec; 56(12):6372-8. Lalezari J, Asmuth D, Casiró A, Vargas H, Lawrence S, Dubuc-Patrick G, Chen J, McCarville J, Pietropaolo K, Zhou XJ, Sullivan-Bólyai J, Mayers D. PMID: 23070151; PMCID: PMC3497200.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during ACTG A5164. J Infect Dis. 2012 Dec 01; 206(11):1715-23. Grant PM, Komarow L, Lederman MM, Pahwa S, Zolopa AR, Andersen J, Asmuth DM, Devaraj S, Pollard RB, Richterman A, Kanthikeel S, Sereti I. PMID: 23002445; PMCID: PMC3488199.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    38. Gastrointestinal-associated lymphoid tissue immune reconstitution in a randomized clinical trial of raltegravir versus non-nucleoside reverse transcriptase inhibitor-based regimens. AIDS. 2012 Aug 24; 26(13):1625-34. Asmuth DM, Ma ZM, Mann S, Knight TH, Yotter T, Albanese A, Melcher GP, Troia-Cancio P, Hayes T, Miller CJ, Pollard RB. PMID: 22820612.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    39. Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings. PLoS Med. 2012; 9(8):e1001290. Campbell TB, Smeaton LM, Kumarasamy N, Flanigan T, Klingman KL, Firnhaber C, Grinsztejn B, Hosseinipour MC, Kumwenda J, Lalloo U, Riviere C, Sanchez J, Melo M, Supparatpinyo K, Tripathy S, Martinez AI, Nair A, Walawander A, Moran L, Chen Y, Snowden W, Rooney JF, Uy J, Schooley RT, De Gruttola V, Hakim JG, PEARLS study team of the ACTG. PMID: 22936892; PMCID: PMC3419182.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    40. Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection. BMC Complement Altern Med. 2012 Jun 29; 12:84. Schunter M, Chu H, Hayes TL, McConnell D, Crawford SS, Luciw PA, Bengmark S, Asmuth DM, Brown J, Bevins CL, Shacklett BL, Critchfield JW. PMID: 22747752; PMCID: PMC3414771.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    41. HIV infection and atherosclerosis: evaluating the drivers of inflammation. Eur J Prev Cardiol. 2013 Oct; 20(5):720-8. Maniar A, Ellis C, Asmuth D, Pollard R, Rutledge J. PMID: 22556374.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    42. Host gene expression changes correlating with anti-HIV-1 effects in human subjects after treatment with peginterferon Alfa-2a. J Infect Dis. 2012 May 01; 205(9):1443-7. Hubbard JJ, Greenwell-Wild T, Barrett L, Yang J, Lempicki RA, Wahl SM, Asmuth DM, Murphy RL, Pollard RB, Kottilil S. PMID: 22454462; PMCID: PMC3324397.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    43. Quantitation of hepatitis C virus RNA in peripheral blood mononuclear cells in HCV-monoinfection and HIV/HCV-coinfection. J Med Virol. 2012 Mar; 84(3):431-7. Chary A, Winters MA, Eisen R, Knight TH, Asmuth DM, Holodniy M. PMID: 22246828.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    44. Interferon-alpha administration enhances CD8+ T cell activation in HIV infection. PLoS One. 2012; 7(1):e30306. Manion M, Rodriguez B, Medvik K, Hardy G, Harding CV, Schooley RT, Pollard R, Asmuth D, Murphy R, Barker E, Brady KE, Landay A, Funderburg N, Sieg SF, Lederman MM. PMID: 22291932; PMCID: PMC3265460.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCellsCTClinical Trials
    45. Molecular characterization of stool microbiota in HIV-infected subjects by panbacterial and order-level 16S ribosomal DNA (rDNA) quantification and correlations with immune activation. J Acquir Immune Defic Syndr. 2011 Aug 15; 57(5):363-70. Ellis CL, Ma ZM, Mann SK, Li CS, Wu J, Knight TH, Yotter T, Hayes TL, Maniar AH, Troia-Cancio PV, Overman HA, Torok NJ, Albanese A, Rutledge JC, Miller CJ, Pollard RB, Asmuth DM. PMID: 21436711; PMCID: PMC3153564.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    46. Lessons from maraviroc clinical trials. Expert Rev Anti Infect Ther. 2011 Jun; 9(6):649-51. Troia-Cancio P, Asmuth DM. PMID: 21692669.
      View in: PubMed   Mentions: 5     Fields:    
    47. HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy. AIDS. 2011 Jan 14; 25(2):159-64. Imamichi H, Degray G, Asmuth DM, Fischl MA, Landay AL, Lederman MM, Sereti I. PMID: 21124203; PMCID: PMC3074174.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    48. CD4+ T-cell restoration after 48 weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2. J Acquir Immune Defic Syndr. 2010 Aug; 54(4):394-7. Asmuth DM, Goodrich J, Cooper DA, Haubrich R, Rajicic N, Hirschel B, Mayer H, Valdez H. PMID: 20009949.
      View in: PubMed   Mentions: 12  Translation:HumansCells
    49. Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial. J Infect Dis. 2010 Jun 01; 201(11):1686-96. Asmuth DM, Murphy RL, Rosenkranz SL, Lertora JJ, Kottilil S, Cramer Y, Chan ES, Schooley RT, Rinaldo CR, Thielman N, Li XD, Wahl SM, Shore J, Janik J, Lempicki RA, Simpson Y, Pollard RB, AIDS Clinical Trials Group A5192 Team. PMID: 20420510; PMCID: PMC2946345.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCellsCTClinical Trials
    50. Impact of highly active antiretroviral therapy on hepatitis C virus protease quasispecies diversity in HIV co-infected patients. J Med Virol. 2010 May; 82(5):791-8. Winters MA, Chary A, Eison R, Asmuth D, Holodniy M. PMID: 20336744.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    51. Comparative cell-mediated immunogenicity of DNA/DNA, DNA/adenovirus type 5 (Ad5), or Ad5/Ad5 HIV-1 clade B gag vaccine prime-boost regimens. J Infect Dis. 2010 Jan 01; 201(1):132-41. Asmuth DM, Brown EL, DiNubile MJ, Sun X, del Rio C, Harro C, Keefer MC, Kublin JG, Dubey SA, Kierstead LS, Casimiro DR, Shiver JW, Robertson MN, Quirk EK, Mehrotra DV. PMID: 19929694.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCellsCTClinical Trials
    52. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood. 2009 Jun 18; 113(25):6304-14. Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, Malaspina A, Morre M, Buffet R, Silvestri G, Lederman MM, ACTG 5214 Study Team. PMID: 19380868; PMCID: PMC2710926.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansCellsCTClinical Trials
    53. UC Davis CTSA: coming of age: integrated programs help put the spotlight on clinical and translational science. Clin Transl Sci. 2009 Apr; 2(2):98-101. Asmuth D, Wun T, Mullen N, Garcia E, Chedin E, Whitney E, Gillis M, Anderson K, Tarantal A, Kenyon N, Curry FR, Berglund L. PMID: 20443878; PMCID: PMC5350674.
      View in: PubMed   Mentions: 2     Fields:    
    54. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science. 2009 Mar 27; 323(5922):1743-7. Hübner W, McNerney GP, Chen P, Dale BM, Gordon RE, Chuang FY, Li XD, Asmuth DM, Huser T, Chen BK. PMID: 19325119; PMCID: PMC2756521.
      View in: PubMed   Mentions: 232     Fields:    Translation:HumansCells
    55. Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjects. J Acquir Immune Defic Syndr. 2009 Mar 01; 50(3):250-8. Skowron G, Spritzler JG, Weidler J, Robbins GK, Johnson VA, Chan ES, Asmuth DM, Gandhi RT, Lie Y, Bates M, Pollard RB, NIH/NIAID ACTG 384 Protocol Team and Monogram Biosciences. PMID: 19194319; PMCID: PMC3482469.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    56. Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384. Clin Infect Dis. 2009 Feb 01; 48(3):350-61. Robbins GK, Spritzler JG, Chan ES, Asmuth DM, Gandhi RT, Rodriguez BA, Skowron G, Skolnik PR, Shafer RW, Pollard RB, AIDS Clinical Trials Group 384 Team. PMID: 19123865; PMCID: PMC2676920.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    57. Low sensitivity of T-cell based detection of tuberculosis among HIV co-infected Tanzanian in-patients. East Afr Med J. 2008 Sep; 85(9):442-9. Seshadri C, Uiso LO, Ostermann J, Diefenthal H, Shao HJ, Chu HY, Asmuth DM, Thielman NM, Bartlett JA, Crump JA. PMID: 19537417; PMCID: PMC3168735.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    58. Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry A. 2008 May; 73(5):411-20. McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM. PMID: 18383309.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    59. Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach. Cytometry A. 2008 May; 73(5):400-10. McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Oxford C, Evans TG, Asmuth DM. PMID: 18383316.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    60. Pegylated interferon-alpha 2a treatment of chronic SIV-infected macaques. J Med Primatol. 2008 Feb; 37(1):26-30. Asmuth DM, Abel K, George MD, Dandekar S, Pollard RB, Miller CJ. PMID: 18199069; PMCID: PMC2674790.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    61. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res. 2007 Oct 01; 67(19):9001-5. Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. PMID: 17909000.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    62. Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy. Neurology. 2007 Jun 12; 68(24):2113-9. Zhou L, Kitch DW, Evans SR, Hauer P, Raman S, Ebenezer GJ, Gerschenson M, Marra CM, Valcour V, Diaz-Arrastia R, Goodkin K, Millar L, Shriver S, Asmuth DM, Clifford DB, Simpson DM, McArthur JC, NARC and ACTG A5117 Study Group. PMID: 17562831.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    63. Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection. J Virol. 2007 Jun; 81(11):5460-71. Critchfield JW, Lemongello D, Walker DH, Garcia JC, Asmuth DM, Pollard RB, Shacklett BL. PMID: 17344302; PMCID: PMC1900284.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    64. Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384. J Acquir Immune Defic Syndr. 2006 Aug 01; 42(4):426-34. Gandhi RT, Spritzler J, Chan E, Asmuth DM, Rodriguez B, Merigan TC, Hirsch MS, Shafer RW, Robbins GK, Pollard RB, ACTG 384 Team. PMID: 16810109.
      View in: PubMed   Mentions: 85  Translation:Humans
    65. HIV neuropathy natural history cohort study: assessment measures and risk factors. Neurology. 2006 Jun 13; 66(11):1679-87. Simpson DM, Kitch D, Evans SR, McArthur JC, Asmuth DM, Cohen B, Goodkin K, Gerschenson M, So Y, Marra CM, Diaz-Arrastia R, Shriver S, Millar L, Clifford DB, ACTG A5117 Study Group. PMID: 16769940.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCTClinical Trials
    66. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis. Prostate. 2006 Jan 01; 66(1):70-81. Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M. PMID: 16114066.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    67. Estimating cell death in G(2)M using bivariate BrdUrd/DNA flow cytometry. Cytometry A. 2005 Jul; 66(1):32-40. White RA, Asmuth DM, Lu Y, Wang N, Li XD, Reece L, Pollard RB, Nokta M, Leary JF, Terry NH. PMID: 15915505.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    68. Cell cycle kinetic dysregulation in HIV-infected normal lymphocytes. Cytometry A. 2005 Jul; 66(1):41-51. Asmuth DM, Wang N, Lu Y, Li XD, Reece L, Terry NH, Pollard RB, Nokta M, Leary JF, White RA. PMID: 15915506.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    69. Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency. AIDS Res Hum Retroviruses. 2005 Apr; 21(4):263-72. Lori F, Pollard RB, Whitman L, Bakare N, Blick G, Shalit P, Foli A, Peterson D, Tennenberg A, Schrader S, Rashbaum B, Farthing C, Herman D, Norris D, Greiger P, Frank I, Groff A, Lova L, Asmuth D, Lisziewicz J. PMID: 15943568.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    70. A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis. Antiviral Res. 2004 Nov; 64(2):103-11. Borucki MJ, Spritzler J, Asmuth DM, Gnann J, Hirsch MS, Nokta M, Aweeka F, Nadler PI, Sattler F, Alston B, Nevin TT, Owens S, Waterman K, Hubbard L, Caliendo A, Pollard RB, AACTG 266 Team. PMID: 15498605.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    71. Treatments for hepatitis B. Clin Infect Dis. 2004 Nov 01; 39(9):1353-62. Asmuth DM, Nguyen HH, Melcher GP, Cohen SH, Pollard RB. PMID: 15494913.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    72. Hepatitis B and C viral load changes following initiation of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection. Antiviral Res. 2004 Aug; 63(2):123-31. Asmuth DM, Busch MP, Laycock ME, Mohr BA, Kalish LA, van der Horst CM, Viral Activation Transfusion Study (VATS) Group. PMID: 15302141.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    73. Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literature. Int J STD AIDS. 2003 May; 14(5):350-5. Rossero R, Asmuth DM, Grady JJ, McKinsey DS, Green S, Andron L, Pollard RB. PMID: 12803944.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    74. Absence of HBV and HCV, HTLV-I and -II, and human herpes virus-8 activation after allogeneic RBC transfusion in patients with advanced HIV-1 infection. Transfusion. 2003 Apr; 43(4):451-8. Asmuth DM, Kalish LA, Laycock ME, Murphy EL, Mohr BA, Lee TH, Gallarda J, Giachetti C, Dollard SC, van der Horst CM, Grant RM, Busch MP, Viral Activation Transfusion Study Group. PMID: 12662277.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    75. Entrapment of recent thymic emigrants in lymphoid tissues from HIV-infected patients: association with HIV cellular viral load. AIDS. 2002 Nov 08; 16(16):2119-27. Nokta MA, Li XD, Al-Harthi L, Nichols J, Pou A, Asmuth D, Landay A, Pollard RB. PMID: 12409732; PMCID: PMC3738871.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    76. Importance of high-throughput cell separation technologies for genomics/proteomics-based clinical diagnostics. Proceedings of SPIE. 2002 Jun 7; 4625:1-8. Leary LJ, Szaniszlo SP, Prow PT, Reece RL, Wang WN, Asmuth AD. .
      View in: Publisher Site   Mentions:
    77. Cytomegalovirus glycoprotein B groups in human immunodeficiency virus-infected patients with incident retinitis. J Infect Dis. 2002 Jul 01; 186(1):114-7. Drew WL, Chou S, Miner RC, Mohr BA, Busch MP, van der Horst CM, Asmuth DM, Kalish LA. PMID: 12089671.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    78. Leukocyte-reduced red blood cell transfusions in patients with anemia and human immunodeficiency virus infection: the Viral Activation Transfusion Study: a randomized controlled trial. JAMA. 2001 Mar 28; 285(12):1592-601. Collier AC, Kalish LA, Busch MP, Gernsheimer T, Assmann SF, Lane TA, Asmuth DM, Lederman MM, Murphy EL, Kumar P, Kelley M, Flanigan TP, McMahon DK, Sacks HS, Kennedy MS, Holland PV, Viral Activation Transfusion Study Group. PMID: 11268267.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    79. Homeostasis of naive and memory T cell subpopulations in peripheral blood and lymphoid tissues in the context of human immunodeficiency virus infection. J Infect Dis. 2001 May 01; 183(9):1336-42. Nokta MA, Li XD, Nichols J, Pou A, Asmuth D, Pollard RB. PMID: 11294664.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    80. Chemokine/CD4 receptor density ratios correlate with HIV replication in lymph node and peripheral blood of HIV-infected individuals. AIDS. 2001 Jan 26; 15(2):161-9. Nokta MA, Li XD, Nichols J, Mallen M, Pou A, Asmuth D, Pollard RB. PMID: 11216923.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    81. Plasma human immunodeficiency virus (HIV) type 1 RNA load in men and women with advanced HIV-1 disease. J Infect Dis. 2000 Aug; 182(2):603-6. Kalish LA, Collier AC, Flanigan TP, Kumar PN. PMID: 10915096.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    82. 'Modeling' relationships among HIV-1 replication, immune activation and CD4+ T-cell losses using adjusted correlative analyses. AIDS. 2000 May 26; 14(8):951-8. Lederman MM, Kalish LA, Asmuth D, Fiebig E, Mileno M, Busch MP. PMID: 10853976.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    83. Changing patterns of infections in patients with AIDS: a study of 279 autopsies of prison inmates and nonincarcerated patients at a university hospital in eastern Texas, 1984-1993. Clin Infect Dis. 1996 Aug; 23(2):241-7. Lyon R, Haque AK, Asmuth DM, Woods GL. PMID: 8842257.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. Effects of Clostridium perfringens recombinant and crude phospholipase C and theta-toxin on rabbit hemodynamic parameters. J Infect Dis. 1995 Nov; 172(5):1317-23. Asmuth DM, Olson RD, Hackett SP, Bryant AE, Tweten RK, Tso JY, Zollman T, Stevens DL. PMID: 7594670.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    85. Diagnosis of intestinal microsporidiosis by examination of stool and duodenal aspirate with Weber's modified trichrome and Uvitex 2B strains. J Clin Microbiol. 1995 Apr; 33(4):805-10. DeGirolami PC, Ezratty CR, Desai G, McCullough A, Asmuth D, Wanke C, Federman M. PMID: 7540626; PMCID: PMC228045.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCTClinical Trials
    86. Microsporidia and diarrhea in AIDS patients. Clinical Microbiology Newsletter. 1994 Dec 1; 16(23):179-183. Asmuth AD. .
      View in: Publisher Site   Mentions:
    87. Clinical features of microsporidiosis in patients with AIDS. Clin Infect Dis. 1994 May; 18(5):819-25. Asmuth DM, DeGirolami PC, Federman M, Ezratty CR, Pleskow DK, Desai G, Wanke CA. PMID: 7915548.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    88. Physiological effects of HIV infection on human intestinal epithelial cells: an in vitro model for HIV enteropathy. AIDS. 1994 Feb; 8(2):205-11. Asmuth DM, Hammer SM, Wanke CA. PMID: 7913816.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
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