Loading...

Dori L Borjesson

TitleDEPARTMENT CHAIR
InstitutionUniversity of California Davis
DepartmentVM: PATHOLOGY, MICRO, & IMMUN
Address4325 Vet Med 3A
CA 95616
Phone530-754-5202
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Mesenchymal Stem Cell Therapy for Gut Mucosal Recovery in the SIV Model of AIDS
    NIH/NIAID R21AI116415May 1, 2015 - Apr 30, 2017
    Role: Co-Principal Investigator
    An Animal Model of Chronic Oral Inflammation for Stem Cell-Based Therapy
    NIH/NIDCR R21DE024711Aug 1, 2014 - Jul 31, 2016
    Role: Principal Investigator
    Granulocytic Ehrlichiosis: Cell-Pathogen Interactions
    NIH/NIAID K08AI051529Apr 1, 2003 - Mar 31, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Woods SJ, Spriet M, Safra N, Cissell DD, Borjesson D. Hounsfield units are a useful predictor of pleural effusion cytological type in dogs but not in cats. Vet Radiol Ultrasound. 2018 Apr 23. PMID: 29687517.
      View in: PubMed
    2. Barberini DJ, Aleman M, Aristizabal F, Spriet M, Clark KC, Walker NJ, Galuppo LD, Amorim RM, Woolard KD, Borjesson D. Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses. Stem Cell Res Ther. 2018 Apr 10; 9(1):96. PMID: 29631634.
      View in: PubMed
    3. White JL, Walker NJ, Hu JC, Borjesson D, Athanasiou KA. A Comparison of Bone Marrow and Cord Blood Mesenchymal Stem Cells for Cartilage Self-Assembly. Tissue Eng Part A. 2018 Apr 02. PMID: 29478385.
      View in: PubMed
    4. Textor JA, Clark KC, Walker NJ, Aristizobal FA, Kol A, LeJeune SS, Bledsoe A, Davidyan A, Gray SN, Bohannon-Worsley LK, Woolard KD, Borjesson D. Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. Stem Cells Transl Med. 2018 Jan; 7(1):98-108. PMID: 29063737.
      View in: PubMed
    5. Clark KC, Fierro FA, Ko EM, Walker NJ, Arzi B, Tepper CG, Dahlenburg H, Cicchetto A, Kol A, Marsh L, Murphy WJ, Fazel N, Borjesson D. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017 03 20; 8(1):69. PMID: 28320483.
      View in: PubMed
    6. Oki AT, Huang B, Beyer AR, May LJ, Truchan HK, Walker NJ, Galloway NL, Borjesson D, Carlyon JA. Anaplasma phagocytophilum APH0032 Is Exposed on the Cytosolic Face of the Pathogen-Occupied Vacuole and Co-opts Host Cell SUMOylation. Front Cell Infect Microbiol. 2016; 6:108. PMID: 27713867.
      View in: PubMed
    7. Owens SD, Kol A, Walker NJ, Borjesson D. Allogeneic Mesenchymal Stem Cell Treatment Induces Specific Alloantibodies in Horses. Stem Cells Int. 2016; 2016:5830103. PMID: 27648075.
      View in: PubMed
    8. Clark KC, Kol A, Shahbenderian S, Granick JL, Walker NJ, Borjesson D. Canine and Equine Mesenchymal Stem Cells Grown in Serum Free Media Have Altered Immunophenotype. Stem Cell Rev. 2016 04; 12(2):245-56. PMID: 26638159.
      View in: PubMed
    9. Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson D. Companion animals: Translational scientist's new best friends. Sci Transl Med. 2015 Oct 07; 7(308):308ps21. PMID: 26446953; PMCID: PMC4806851 [Available on 10/07/16].
    10. McMahill BG, Spriet M, Sisó S, Manzer MD, Mitchell G, McGee J, Garcia TC, Borjesson D, Sieber-Blum M, Nolta JA, Sturges BK. Feasibility Study of Canine Epidermal Neural Crest Stem Cell Transplantation in the Spinal Cords of Dogs. Stem Cells Transl Med. 2015 Oct; 4(10):1173-86. PMID: 26273065; PMCID: PMC4572898 [Available on 10/01/16].
    11. Kol A, Wood JA, Carrade Holt DD, Gillette JA, Bohannon-Worsley LK, Puchalski SM, Walker NJ, Clark KC, Watson JL, Borjesson D. Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses. Stem Cell Res Ther. 2015 Apr 15; 6:73. PMID: 25888916; PMCID: PMC4446064.
    12. Morgan JT, Kwon HS, Wood JA, Borjesson D, Tomarev SI, Murphy CJ, Russell P. Thermally labile components of aqueous humor potently induce osteogenic potential in adipose-derived mesenchymal stem cells. Exp Eye Res. 2015 Jun; 135:127-33. PMID: 25720657; PMCID: PMC4446238.
    13. McMahill BG, Borjesson D, Sieber-Blum M, Nolta JA, Sturges BK. Stem cells in canine spinal cord injury--promise for regenerative therapy in a large animal model of human disease. Stem Cell Rev. 2015 Feb; 11(1):180-93. PMID: 25173879.
      View in: PubMed
    14. Adedeji AO, Borjesson D, Kozikowski-Nicholas TA, Cartoceti AN, Prutton J, Aleman M. What is your diagnosis? Cerebrospinal fluid from a horse. Vet Clin Pathol. 2015 Mar; 44(1):171-2. PMID: 25639591.
      View in: PubMed
    15. Burton AG, Clark KC, Borjesson D, Carrade DD, Burges J, Owens SD. Equine bone marrow volume reduction, red blood cell depletion, and mononuclear cell recovery using the PrepaCyte-CB processing system. Vet Clin Pathol. 2015 Jun; 44(2):188-93. PMID: 25627833.
      View in: PubMed
    16. Spriet M, Hunt GB, Walker NJ, Borjesson D. Scintigraphic tracking of mesenchymal stem cells after portal, systemic intravenous and splenic administration in healthy beagle dogs. Vet Radiol Ultrasound. 2015 May-Jun; 56(3):327-34. PMID: 25582730.
      View in: PubMed
    17. Arzi B, Kol A, Murphy B, Walker NJ, Wood JA, Clark K, Verstraete FJ, Borjesson D. Feline foamy virus adversely affects feline mesenchymal stem cell culture and expansion: implications for animal model development. Stem Cells Dev. 2015 Apr 01; 24(7):814-23. PMID: 25404388; PMCID: PMC4367494.
    18. Beyer AR, Truchan HK, May LJ, Walker NJ, Borjesson D, Carlyon JA. The Anaplasma phagocytophilum effector AmpA hijacks host cell SUMOylation. Cell Microbiol. 2015 Apr; 17(4):504-19. PMID: 25308709; PMCID: PMC4664186.
    19. Burton AG, Borjesson D, Vernau W. Thymoma-associated lymphocytosis in a dog. Vet Clin Pathol. 2014 Dec; 43(4):584-8. PMID: 25295998.
      View in: PubMed
    20. Kol A, Foutouhi S, Walker NJ, Kong NT, Weimer BC, Borjesson D. Gastrointestinal microbes interact with canine adipose-derived mesenchymal stem cells in vitro and enhance immunomodulatory functions. Stem Cells Dev. 2014 Aug 15; 23(16):1831-43. PMID: 24803072; PMCID: PMC4120524.
    21. Seidman D, Ojogun N, Walker NJ, Mastronunzio J, Kahlon A, Hebert KS, Karandashova S, Miller DP, Tegels BK, Marconi RT, Fikrig E, Borjesson D, Carlyon JA. Anaplasma phagocytophilum surface protein AipA mediates invasion of mammalian host cells. Cell Microbiol. 2014 Aug; 16(8):1133-45. PMID: 24612118; PMCID: PMC4115035.
    22. Carrade Holt DD, Wood JA, Granick JL, Walker NJ, Clark KC, Borjesson D. Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells Dev. 2014 Jun 01; 23(11):1258-65. PMID: 24438346.
      View in: PubMed
    23. Morgan JT, Wood JA, Walker NJ, Raghunathan VK, Borjesson D, Murphy CJ, Russell P. Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells. J Ocul Pharmacol Ther. 2014 Mar-Apr; 30(2-3):254-66. PMID: 24456002; PMCID: PMC3991981.
    24. Gericota B, Anderson JS, Mitchell G, Borjesson D, Sturges BK, Nolta JA, Sieber-Blum M. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury. Stem Cells Transl Med. 2014 Mar; 3(3):334-45. PMID: 24443004; PMCID: PMC3952930.
    25. Park SA, Reilly CM, Wood JA, Chung DJ, Carrade DD, Deremer SL, Seraphin RL, Clark KC, Zwingenberger AL, Borjesson D, Hayashi K, Russell P, Murphy CJ. Safety and immunomodulatory effects of allogeneic canine adipose-derived mesenchymal stromal cells transplanted into the region of the lacrimal gland, the gland of the third eyelid and the knee joint. Cytotherapy. 2013 Dec; 15(12):1498-510. PMID: 23992828.
      View in: PubMed
    26. Granick JL, Falahee PC, Dahmubed D, Borjesson D, Miller LS, Simon SI. Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE2 stimulates granulopoiesis in wounds. Blood. 2013 Sep 05; 122(10):1770-8. PMID: 23869087; PMCID: PMC3765058.
    27. Toupadakis CA, Granick JL, Sagy M, Wong A, Ghassemi E, Chung DJ, Borjesson D, Yellowley CE. Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model. Cytotherapy. 2013 Sep; 15(9):1136-47. PMID: 23831362; PMCID: PMC3735657.
    28. Carrade DD, Borjesson D. Immunomodulation by mesenchymal stem cells in veterinary species. Comp Med. 2013 Jun; 63(3):207-17. PMID: 23759523; PMCID: PMC3690426.
    29. Kahlon A, Ojogun N, Ragland SA, Seidman D, Troese MJ, Ottens AK, Mastronunzio JE, Truchan HK, Walker NJ, Borjesson D, Fikrig E, Carlyon JA. Anaplasma phagocytophilum Asp14 is an invasin that interacts with mammalian host cells via its C terminus to facilitate infection. Infect Immun. 2013 Jan; 81(1):65-79. PMID: 23071137; PMCID: PMC3536139.
    30. Ojogun N, Kahlon A, Ragland SA, Troese MJ, Mastronunzio JE, Walker NJ, Viebrock L, Thomas RJ, Borjesson D, Fikrig E, Carlyon JA. Anaplasma phagocytophilum outer membrane protein A interacts with sialylated glycoproteins to promote infection of mammalian host cells. Infect Immun. 2012 Nov; 80(11):3748-60. PMID: 22907813; PMCID: PMC3486060.
    31. Wood JA, Ly I, Borjesson D, Nealey PF, Russell P, Murphy CJ. The modulation of canine mesenchymal stem cells by nano-topographic cues. Exp Cell Res. 2012 Nov 15; 318(19):2438-45. PMID: 22771362; PMCID: PMC3650715.
    32. Inoue H, Clifford DL, Vickers TW, Coonan TJ, Garcelon DK, Borjesson D. Biochemical and hematologic reference intervals for the endangered island fox (Urocyon littoralis). J Wildl Dis. 2012 Jul; 48(3):583-92. PMID: 22740524.
      View in: PubMed
    33. Granick JL, Simon SI, Borjesson D. Hematopoietic stem and progenitor cells as effectors in innate immunity. Bone Marrow Res. 2012; 2012:165107. PMID: 22762001; PMCID: PMC3385697.
    34. Mudge MC, Walker NJ, Borjesson D, Librach F, Johns JL, Owens SD. Post-transfusion survival of biotin-labeled allogeneic RBCs in adult horses. Vet Clin Pathol. 2012 Mar; 41(1):56-62. PMID: 22251607.
      View in: PubMed
    35. Carrade DD, Lame MW, Kent MS, Clark KC, Walker NJ, Borjesson D. Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells(). Cell Med. 2012; 4(1):1-11. PMID: 23152950.
      View in: PubMed
    36. Wood JA, Chung DJ, Park SA, Zwingenberger AL, Reilly CM, Ly I, Walker NJ, Vernau W, Hayashi K, Wisner ER, Cannon MS, Kass PH, Cherry SR, Borjesson D, Russell P, Murphy CJ. Periocular and intra-articular injection of canine adipose-derived mesenchymal stem cells: an in vivo imaging and migration study. J Ocul Pharmacol Ther. 2012 Jun; 28(3):307-17. PMID: 22175793; PMCID: PMC3361184.
    37. Owens SD, Burges J, Johns JL, Carrade DD, Galuppo LD, Librach F, Borjesson D. Processing of equine bone marrow using the automated MarrowXpress System: RBC depletion, volume reduction, and mononuclear cell recovery. Vet Clin Pathol. 2011 Dec; 40(4):444-449. PMID: 22092275.
      View in: PubMed
    38. Carrade DD, Affolter VK, Outerbridge CA, Watson JL, Galuppo LD, Buerchler S, Kumar V, Walker NJ, Borjesson D. Intradermal injections of equine allogeneic umbilical cord-derived mesenchymal stem cells are well tolerated and do not elicit immediate or delayed hypersensitivity reactions. Cytotherapy. 2011 Nov; 13(10):1180-92. PMID: 21899391.
      View in: PubMed
    39. Troese MJ, Kahlon A, Ragland SA, Ottens AK, Ojogun N, Nelson KT, Walker NJ, Borjesson D, Carlyon JA. Proteomic analysis of Anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored cell. Infect Immun. 2011 Nov; 79(11):4696-707. PMID: 21844238; PMCID: PMC3257945.
    40. Peroni JF, Borjesson D. Anti-inflammatory and immunomodulatory activities of stem cells. Vet Clin North Am Equine Pract. 2011 Aug; 27(2):351-62. PMID: 21872763.
      View in: PubMed
    41. Vidal MA, Walker NJ, Napoli E, Borjesson D. Evaluation of senescence in mesenchymal stem cells isolated from equine bone marrow, adipose tissue, and umbilical cord tissue. Stem Cells Dev. 2012 Jan 20; 21(2):273-83. PMID: 21410356.
      View in: PubMed
    42. Borjesson D, Peroni JF. The regenerative medicine laboratory: facilitating stem cell therapy for equine disease. Clin Lab Med. 2011 Mar; 31(1):109-23. PMID: 21295725.
      View in: PubMed
    43. Mylonakis ME, Borjesson D, Leontides L, Siarkou VI, Theodorou K, Koutinas AF. Cytologic patterns of lymphadenopathy in canine monocytic ehrlichiosis. Vet Clin Pathol. 2011 Mar; 40(1):78-83. PMID: 21291487.
      View in: PubMed
    44. Kim MH, Granick JL, Kwok C, Walker NJ, Borjesson D, Curry FR, Miller LS, Simon SI. Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. 2011 Mar 24; 117(12):3343-52. PMID: 21278352; PMCID: PMC3069674.
    45. MacNamara KC, Oduro K, Martin O, Jones DD, McLaughlin M, Choi K, Borjesson D, Winslow GM. Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFN-? signaling. J Immunol. 2011 Jan 15; 186(2):1032-43. PMID: 21149601; PMCID: PMC3178067.
    46. Carrade DD, Owens SD, Galuppo LD, Vidal MA, Ferraro GL, Librach F, Buerchler S, Friedman MS, Walker NJ, Borjesson D. Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses. Cytotherapy. 2011 Apr; 13(4):419-30. PMID: 21105841.
      View in: PubMed
    47. Kol A, Borjesson D. Application of thrombelastography/thromboelastometry to veterinary medicine. Vet Clin Pathol. 2010 Dec; 39(4):405-16. PMID: 20969608.
      View in: PubMed
    48. Toupadakis CA, Wong A, Genetos DC, Cheung WK, Borjesson D, Ferraro GL, Galuppo LD, Leach JK, Owens SD, Yellowley CE. Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood, and umbilical cord tissue. Am J Vet Res. 2010 Oct; 71(10):1237-45. PMID: 20919913.
      View in: PubMed
    49. Owens SD, Johns JL, Walker NJ, Librach FA, Carrade DD, Tablin F, Borjesson D. Use of an in vitro biotinylation technique for determination of posttransfusion survival of fresh and stored autologous red blood cells in Thoroughbreds. Am J Vet Res. 2010 Aug; 71(8):960-6. PMID: 20673097.
      View in: PubMed
    50. Huang B, Troese MJ, Howe D, Ye S, Sims JT, Heinzen RA, Borjesson D, Carlyon JA. Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane. Microb Pathog. 2010 Nov; 49(5):273-84. PMID: 20600793; PMCID: PMC2919654.
    51. Huang B, Troese MJ, Ye S, Sims JT, Galloway NL, Borjesson D, Carlyon JA. Anaplasma phagocytophilum APH_1387 is expressed throughout bacterial intracellular development and localizes to the pathogen-occupied vacuolar membrane. Infect Immun. 2010 May; 78(5):1864-73. PMID: 20212090; PMCID: PMC2863503.
    52. Schuh EM, Friedman MS, Carrade DD, Li J, Heeke D, Oyserman SM, Galuppo LD, Lara DJ, Walker NJ, Ferraro GL, Owens SD, Borjesson D. Identification of variables that optimize isolation and culture of multipotent mesenchymal stem cells from equine umbilical-cord blood. Am J Vet Res. 2009 Dec; 70(12):1526-35. PMID: 19951125.
      View in: PubMed
    53. Borjesson D, Macnamara K, Johns J, Winslow G. Anaplasma phagocytophilum and Ehrlichia muris induce cytopenias and global defects in hematopoiesis. Clin Microbiol Infect. 2009 Dec; 15 Suppl 2:66-7. PMID: 19793126; PMCID: PMC3178063.
    54. MacNamara KC, Racine R, Chatterjee M, Borjesson D, Winslow GM. Diminished hematopoietic activity associated with alterations in innate and adaptive immunity in a mouse model of human monocytic ehrlichiosis. Infect Immun. 2009 Sep; 77(9):4061-9. PMID: 19451243; PMCID: PMC2738008.
    55. Johns JL, Luff JA, Shooshtari MP, Zehnder AM, Borjesson D. What is your diagnosis? Blood smear from an injured red-tailed hawk. Vet Clin Pathol. 2009 Jun; 38(2):247-52. PMID: 19228359.
      View in: PubMed
    56. Granick JL, Reneer DV, Carlyon JA, Borjesson D. Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production. J Med Microbiol. 2008 Apr; 57(Pt 4):416-23. PMID: 18349358.
      View in: PubMed
    57. Kim MH, Liu W, Borjesson D, Curry FR, Miller LS, Cheung AL, Liu FT, Isseroff RR, Simon SI. Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol. 2008 Jul; 128(7):1812-20. PMID: 18185533; PMCID: PMC2617712.
    58. Borjesson D. Culture, isolation, and labeling of Anaplasma phagocytophilum for subsequent infection of human neutrophils. Methods Mol Biol. 2008; 431:159-71. PMID: 18287755.
      View in: PubMed
    59. Overmann JA, Sharkey LC, Weiss DJ, Borjesson D. Performance of 2 microtiter canine Coombs' tests. Vet Clin Pathol. 2007 Jun; 36(2):179-83. PMID: 17523092.
      View in: PubMed
    60. Brazzell JL, Borjesson D. Evaluation of plasma antithrombin activity and D-dimer concentration in populations of healthy cats, clinically ill cats, and cats with cardiomyopathy. Vet Clin Pathol. 2007 Mar; 36(1):79-84. PMID: 17311199.
      View in: PubMed
    61. Brazzell JL, Borjesson D. Intra-abdominal mass aspirate from an alopecic dog. Vet Clin Pathol. 2006 Jun; 35(2):259-62. PMID: 16783726.
      View in: PubMed
    62. Brazzell JL, Kaese HJ, Borjesson D. Bold fusion: transtracheal wash from a Jersey calf. Vet Clin Pathol. 2006 Jun; 35(2):247-9. PMID: 16783723.
      View in: PubMed
    63. Borjesson D, Brazzell JL, Feferman R. Platelet dysfunction after association with Anaplasma phagocytophilum in vitro. Ann N Y Acad Sci. 2005 Dec; 1063:413-5. PMID: 16481550.
      View in: PubMed
    64. Borjesson D, Kobayashi SD, Whitney AR, Voyich JM, Argue CM, Deleo FR. Insights into pathogen immune evasion mechanisms: Anaplasma phagocytophilum fails to induce an apoptosis differentiation program in human neutrophils. J Immunol. 2005 May 15; 174(10):6364-72. PMID: 15879137.
      View in: PubMed
    65. Borjesson D, Simon SI, Hodzic E, DeCock HE, Ballantyne CM, Barthold SW. Roles of neutrophil beta 2 integrins in kinetics of bacteremia, extravasation, and tick acquisition of Anaplasma phagocytophila in mice. Blood. 2003 Apr 15; 101(8):3257-64. PMID: 12480703.
      View in: PubMed
    66. Borjesson D, Barthold SW. The mouse as a model for investigation of human granulocytic ehrlichiosis: current knowledge and future directions. Comp Med. 2002 Oct; 52(5):403-13. PMID: 12405632.
      View in: PubMed
    67. Hodzic E, Feng S, Freet KJ, Borjesson D, Barthold SW. Borrelia burgdorferi population kinetics and selected gene expression at the host-vector interface. Infect Immun. 2002 Jul; 70(7):3382-8. PMID: 12065476; PMCID: PMC128091.
    68. Borjesson D, Simon SI, Hodzic E, Ballantyne CM, Barthold SW. Kinetics of CD11b/CD18 up-regulation during infection with the agent of human granulocytic ehrlichiosis in mice. Lab Invest. 2002 Mar; 82(3):303-11. PMID: 11896209.
      View in: PubMed
    69. Borjesson D, Christopher MM, Ling GV. Detection of canine transitional cell carcinoma using a bladder tumor antigen urine dipstick test. Vet Clin Pathol. 1999; 28(1):33-38. PMID: 12075535.
      View in: PubMed