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Edward S Schelegle

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InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shaffo FC, Grodzki AC, Schelegle E, Lein PJ. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats. Toxicol Sci. 2018 Jun 25. PMID: 29939342.
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    2. Wong EM, Walby WF, Wilson DW, Tablin F, Schelegle E. Ultrafine Particulate Matter Combined With Ozone Exacerbates Lung Injury in Mature Adult Rats With Cardiovascular Disease. Toxicol Sci. 2018 May 01; 163(1):140-151. PMID: 29394414.
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    3. Miller LA, Royer CM, Pinkerton KE, Schelegle E. Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. ILAR J. 2017 Dec 01; 58(2):269-280. PMID: 29216343.
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    4. Crowley CM, Fontaine JH, Gerriets JE, Schelegle E, Hyde DM, Miller LA. Early life allergen and air pollutant exposures alter longitudinal blood immune profiles in infant rhesus monkeys. Toxicol Appl Pharmacol. 2017 08 01; 328:60-69. PMID: 28529118.
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    5. Black C, Gerriets JE, Fontaine JH, Harper RW, Kenyon NJ, Tablin F, Schelegle E, Miller LA. Early Life Wildfire Smoke Exposure Is Associated with Immune Dysregulation and Lung Function Decrements in Adolescence. Am J Respir Cell Mol Biol. 2017 05; 56(5):657-666. PMID: 28208028.
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    6. Lynn TM, Molloy EL, Masterson JC, Glynn SF, Costello RW, Avdalovic MV, Schelegle E, Miller LA, Hyde DM, O'Dea S. SMAD Signaling in the Airways of Healthy Rhesus Macaques versus Rhesus Macaques with Asthma Highlights a Relationship Between Inflammation and Bone Morphogenetic Proteins. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):562-73. PMID: 26414797.
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    7. Figueroa JA, Mansoor JK, Allen RP, Davis CE, Walby WF, Aksenov AA, Zhao W, Lewis WR, Schelegle E. Exhaled volatile organic compounds in individuals with a history of high altitude pulmonary edema and varying hypoxia-induced responses. J Breath Res. 2015 Apr 20; 9(2):026004. PMID: 25891856.
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    8. Herring MJ, Putney LF, St George JA, Avdalovic MV, Schelegle E, Miller LA, Hyde DM. Early life exposure to allergen and ozone results in altered development in adolescent rhesus macaque lungs. Toxicol Appl Pharmacol. 2015 Feb 15; 283(1):35-41. PMID: 25545987.
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    9. Murphy SR, Oslund KL, Hyde DM, Miller LA, Van Winkle LS, Schelegle E. Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15; 307(6):L471-81. PMID: 25063800; PMCID: PMC4166783.
    10. Moore BD, Hyde DM, Miller LA, Wong EM, Schelegle E. Persistence of serotonergic enhancement of airway response in a model of childhood asthma. Am J Respir Cell Mol Biol. 2014 Jul; 51(1):77-85. PMID: 24484440.
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    11. Allen RP, Schelegle E, Bennett SH. Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H405-17. PMID: 24858853.
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    12. Mansoor JK, Schelegle E, Davis CE, Walby WF, Zhao W, Aksenov AA, Pasamontes A, Figueroa J, Allen R. Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension. PLoS One. 2014; 9(4):e95331. PMID: 24748102; PMCID: PMC3991617.
    13. Chun K, Miller LA, Schelegle E, Hyde DM, Capitanio JP. Behavioral inhibition in rhesus monkeys (Macaca mulatta) is related to the airways response, but not immune measures, commonly associated with asthma. PLoS One. 2013; 8(8):e71575. PMID: 23951195; PMCID: PMC3739724.
    14. Murphy SR, Schelegle E, Miller LA, Hyde DM, Van Winkle LS. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicol Sci. 2013 Jul; 134(1):168-79. PMID: 23570994; PMCID: PMC3693130.
    15. Davis BB, Zeki AA, Bratt JM, Wang L, Filosto S, Walby WF, Kenyon NJ, Goldkorn T, Schelegle E, Pinkerton KE. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. Eur Respir J. 2013 Aug; 42(2):350-61. PMID: 23180589.
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    16. Asgharian B, Price O, McClellan G, Corley R, Einstein DR, Jacob RE, Harkema J, Carey SA, Schelegle E, Hyde D, Kimbell JS, Miller FJ. Development of a rhesus monkey lung geometry model and application to particle deposition in comparison to humans. Inhal Toxicol. 2012 Nov; 24(13):869-99. PMID: 23121298.
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    17. Murphy SR, Schelegle E, Edwards PC, Miller LA, Hyde DM, Van Winkle LS. Postnatal exposure history and airways: oxidant stress responses in airway explants. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):815-23. PMID: 22962062; PMCID: PMC3547096.
    18. Avdalovic MV, Tyler NK, Putney L, Nishio SJ, Quesenberry S, Singh PJ, Miller LA, Schelegle E, Plopper CG, Vu T, Hyde DM. Ozone exposure during the early postnatal period alters the timing and pattern of alveolar growth and development in nonhuman primates. Anat Rec (Hoboken). 2012 Oct; 295(10):1707-16. PMID: 22887719.
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    19. McDonnell WF, Stewart PW, Smith MV, Kim CS, Schelegle E. Prediction of lung function response for populations exposed to a wide range of ozone conditions. Inhal Toxicol. 2012 Aug; 24(10):619-33. PMID: 22906168.
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    20. Plopper CG, Joad JP, Miller LA, Schelegle E, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Lasley WL, Buckpitt AR, Pinkerton KE, Tarkington BK, Davis S, Nishio SJ, Gershwin LJ, Wu R, Hyde DM. Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clin Exp Allergy. 2012 Jul; 42(7):1104-18. PMID: 22702509; PMCID: PMC3913647.
    21. Schelegle E, Adams WC, Walby WF, Marion MS. Modelling of individual subject ozone exposure response kinetics. Inhal Toxicol. 2012 Jun; 24(7):401-15. PMID: 22642289.
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    22. Moore BD, Hyde D, Miller L, Wong E, Frelinger J, Schelegle E. Allergen and ozone exacerbate serotonin-induced increases in airway smooth muscle contraction in a model of childhood asthma. Respiration. 2012; 83(6):529-42. PMID: 22507883.
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    23. Schelegle E, Walby WF. Vagal afferents contribute to exacerbated airway responses following ozone and allergen challenge. Respir Physiol Neurobiol. 2012 May 31; 181(3):277-85. PMID: 22525484; PMCID: PMC3366056.
    24. Chou DL, Gerriets JE, Schelegle E, Hyde DM, Miller LA. Increased CCL24/eotaxin-2 with postnatal ozone exposure in allergen-sensitized infant monkeys is not associated with recruitment of eosinophils to airway mucosa. Toxicol Appl Pharmacol. 2011 Dec 15; 257(3):309-18. PMID: 21945493; PMCID: PMC3226879.
    25. Abbas AR, Jackman JK, Bullens SL, Davis SM, Choy DF, Fedorowicz G, Tan M, Truong BT, Gloria Meng Y, Diehl L, Miller LA, Schelegle E, Hyde DM, Clark HF, Modrusan Z, Arron JR, Wu LC. Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model. Am J Pathol. 2011 Oct; 179(4):1667-80. PMID: 21819959; PMCID: PMC3181391.
    26. Capitanio JP, Miller LA, Schelegle E, Mendoza SP, Mason WA, Hyde DM. Behavioral inhibition is associated with airway hyperresponsiveness but not atopy in a monkey model of asthma. Psychosom Med. 2011 May; 73(4):288-94. PMID: 21536834; PMCID: PMC3090450.
    27. Lee D, Wallis C, Wexler AS, Schelegle E, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer B, Kennedy IM, Chan JK. Small particles disrupt postnatal airway development. J Appl Physiol (1985). 2010 Oct; 109(4):1115-24. PMID: 20634362; PMCID: PMC4182294.
    28. Van Winkle LS, Baker GL, Chan JK, Schelegle E, Plopper CG. Airway mast cells in a rhesus model of childhood allergic airways disease. Toxicol Sci. 2010 Jul; 116(1):313-22. PMID: 20403968; PMCID: PMC2886865.
    29. Oslund KL, Hyde DM, Putney LF, Alfaro MF, Walby WF, Tyler NK, Schelegle E. Activation of calcitonin gene-related peptide receptor during ozone inhalation contributes to airway epithelial injury and repair. Toxicol Pathol. 2009 Oct; 37(6):805-13. PMID: 19700657.
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    30. Schelegle E, Morales CA, Walby WF, Marion S, Allen RP. 6.6-hour inhalation of ozone concentrations from 60 to 87 parts per billion in healthy humans. Am J Respir Crit Care Med. 2009 Aug 01; 180(3):265-72. PMID: 19447899.
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    31. Miller LA, Gerriets JE, Tyler NK, Abel K, Schelegle E, Plopper CG, Hyde DM. Ozone and allergen exposure during postnatal development alters the frequency and airway distribution of CD25+ cells in infant rhesus monkeys. Toxicol Appl Pharmacol. 2009 Apr 01; 236(1):39-48. PMID: 19371618; PMCID: PMC2670960.
    32. Oslund KL, Hyde DM, Putney LF, Alfaro MF, Walby WF, Tyler NK, Schelegle E. Activation of neurokinin-1 receptors during ozone inhalation contributes to epithelial injury and repair. Am J Respir Cell Mol Biol. 2008 Sep; 39(3):279-88. PMID: 18390473; PMCID: PMC2542446.
    33. Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle E, Hyde DM, Wu LC, Hymowitz SG, Martin F. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J Clin Invest. 2007 Dec; 117(12):3868-78. PMID: 18060034; PMCID: PMC2096422.
    34. Joad JP, Kott KS, Bric JM, Schelegle E, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE. The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone. Toxicol Appl Pharmacol. 2008 Jan 15; 226(2):153-60. PMID: 17991502.
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    35. Alfaro MF, Walby WF, Adams WC, Schelegle E. Breath condensate levels of 8-isoprostane and leukotriene B4 after ozone inhalation are greater in sensitive versus nonsensitive subjects. Exp Lung Res. 2007 Apr-May; 33(3-4):115-33. PMID: 17558675.
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    36. Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle E, Pieczarka EM, Wu R, Hyde DM. Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology? Toxicol Pathol. 2007 Jan; 35(1):97-110. PMID: 17325978.
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    37. Schelegle E, Walby WF, Adams WC. Time course of ozone-induced changes in breathing pattern in healthy exercising humans. J Appl Physiol (1985). 2007 Feb; 102(2):688-97. PMID: 17082379.
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    38. Mansoor JK, Decile KC, Giri SN, Pinkerton KE, Walby WF, Bratt JM, Grewal H, Margolin SB, Schelegle E. Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma. Pulm Pharmacol Ther. 2007; 20(6):660-8. PMID: 17049446.
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    39. Avdalovic MV, Putney LF, Schelegle E, Miller L, Usachenko JL, Tyler NK, Plopper CG, Gershwin LJ, Hyde DM. Vascular remodeling is airway generation-specific in a primate model of chronic asthma. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1069-76. PMID: 16931639; PMCID: PMC2648107.
    40. Fanucchi MV, Plopper CG, Evans MJ, Hyde DM, Van Winkle LS, Gershwin LJ, Schelegle E. Cyclic exposure to ozone alters distal airway development in infant rhesus monkeys. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L644-50. PMID: 16648242.
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    41. Kajekar R, Pieczarka EM, Smiley-Jewell SM, Schelegle E, Fanucchi MV, Plopper CG. Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium. Respir Physiol Neurobiol. 2007 Jan 15; 155(1):55-63. PMID: 16616710.
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    42. Dybas JM, Andresen CJ, Schelegle E, McCue RW, Callender NN, Jackson AC. Deep-breath frequency in bronchoconstricted monkeys (Macaca fascicularis). J Appl Physiol (1985). 2006 Mar; 100(3):786-91. PMID: 16467390.
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    43. Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle E, Gershwin LJ, Pinkerton KE. Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone. Toxicol Appl Pharmacol. 2006 Aug 01; 214(3):237-43. PMID: 16466656.
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    44. Reinero CR, Byerly JR, Berghaus RD, Berghaus LJ, Schelegle E, Hyde DM, Gershwin LJ. Rush immunotherapy in an experimental model of feline allergic asthma. Vet Immunol Immunopathol. 2006 Mar 15; 110(1-2):141-53. PMID: 16325921.
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    45. Miller LA, Hurst SD, Coffman RL, Tyler NK, Stovall MY, Chou DL, Putney LF, Gershwin LJ, Schelegle E, Plopper CG, Hyde DM. Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys. Clin Exp Allergy. 2005 Jul; 35(7):894-906. PMID: 16008676; PMCID: PMC3918236.
    46. Reinero CR, Decile KC, Byerly JR, Berghaus RD, Walby WE, Berghaus LJ, Hyde DM, Schelegle E, Gershwin LJ. Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma. Am J Vet Res. 2005 Jul; 66(7):1121-7. PMID: 16111148.
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    47. Chou DL, Daugherty BL, McKenna EK, Hsu WM, Tyler NK, Plopper CG, Hyde DM, Schelegle E, Gershwin LJ, Miller LA. Chronic aeroallergen during infancy enhances eotaxin-3 expression in airway epithelium and nerves. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):1-8. PMID: 15834047; PMCID: PMC2715301.
    48. Mansoor JK, Morrissey BM, Walby WF, Yoneda KY, Juarez M, Kajekar R, Severinghaus JW, Eldridge MW, Schelegle E. L-arginine supplementation enhances exhaled NO, breath condensate VEGF, and headache at 4,342 m. High Alt Med Biol. 2005; 6(4):289-300. PMID: 16351563.
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    49. Tran MU, Weir AJ, Fanucchi MV, Rodriguez AE, Pantle LM, Smiley-Jewell SM, Van Winkle LS, Evans MJ, Miller LA, Schelegle E, Gershwin LJ, Hyde DM, Plopper CG. Smooth muscle hypertrophy in distal airways of sensitized infant rhesus monkeys exposed to house dust mite allergen. Clin Exp Allergy. 2004 Oct; 34(10):1627-33. PMID: 15479280.
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    50. Tran MU, Weir AJ, Fanucchi MV, Murphy AE, Van Winkle LS, Evans MJ, Smiley-Jewell SM, Miller L, Schelegle E, Gershwin LJ, Hyde DM, Plopper CG. Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys. J Appl Physiol (1985). 2004 Dec; 97(6):2364-71; discussion 2354. PMID: 15347627.
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    51. Norris Reinero CR, Decile KC, Berghaus RD, Williams KJ, Leutenegger CM, Walby WF, Schelegle E, Hyde DM, Gershwin LJ. An experimental model of allergic asthma in cats sensitized to house dust mite or bermuda grass allergen. Int Arch Allergy Immunol. 2004 Oct; 135(2):117-31. PMID: 15345910.
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    52. Fanucchi MV, Schelegle E, Baker GL, Evans MJ, McDonald RJ, Gershwin LJ, Raz E, Hyde DM, Plopper CG, Miller LA. Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys. Am J Respir Crit Care Med. 2004 Dec 01; 170(11):1153-7. PMID: 15306532; PMCID: PMC3927836.
    53. Van Winkle LS, Fanucchi MV, Miller LA, Baker GL, Gershwin LJ, Schelegle E, Hyde DM, Evans MJ, Plopper CG. Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development. J Appl Physiol (1985). 2004 Dec; 97(6):2355-63; discussion 2354. PMID: 15298983.
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    54. Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle E, Gershwin LJ, Miller LA, Hyde DM, Plopper CG. The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery. Clin Exp Allergy. 2004 Jul; 34(7):1131-6. PMID: 15248862.
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    55. Larson SD, Plopper CG, Baker G, Tarkington BK, Decile KC, Pinkerton K, Mansoor JK, Hyde DM, Schelegle E. Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L286-95. PMID: 15064227.
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    56. Alfaro MF, Putney L, Tarkington BK, Hatch GE, Hyde DM, Schelegle E. Effect of rapid shallow breathing on the distribution of 18O-labeled ozone reaction product in the respiratory tract of the rat. Inhal Toxicol. 2004 Feb; 16(2):77-85. PMID: 15204780.
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    57. Larson SD, Schelegle E, Walby WF, Gershwin LJ, Fanuccihi MV, Evans MJ, Joad JP, Tarkington BK, Hyde DM, Plopper CG. Postnatal remodeling of the neural components of the epithelial-mesenchymal trophic unit in the proximal airways of infant rhesus monkeys exposed to ozone and allergen. Toxicol Appl Pharmacol. 2004 Feb 01; 194(3):211-20. PMID: 14761677.
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    58. Norris CR, Decile KC, Byerly JR, Berghaus RD, Schelegle E, Hyde DM, Gershwin LJ. Production of polyclonal antisera against feline immunoglobulin E and its use in an ELISA in cats with experimentally induced asthma. Vet Immunol Immunopathol. 2003 Dec 15; 96(3-4):149-57. PMID: 14592728.
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    59. Norris CR, Byerly JR, Decile KC, Berghaus RD, Walby WF, Schelegle E, Hyde DM, Gershwin LJ. Allergen-specific IgG and IgA in serum and bronchoalveolar lavage fluid in a model of experimental feline asthma. Vet Immunol Immunopathol. 2003 Dec 15; 96(3-4):119-27. PMID: 14592725.
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    60. Miller LA, Plopper CG, Hyde DM, Gerriets JE, Pieczarka EM, Tyler NK, Evans MJ, Gershwin LJ, Schelegle E, Van Winkle LS. Immune and airway effects of house dust mite aeroallergen exposures during postnatal development of the infant rhesus monkey. Clin Exp Allergy. 2003 Dec; 33(12):1686-94. PMID: 14656356.
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    61. Norris CR, Decile KC, Berghaus LJ, Berghaus RD, Walby WF, Schelegle E, Hyde DM, Gershwin LJ. Concentrations of cysteinyl leukotrienes in urine and bronchoalveolar lavage fluid of cats with experimentally induced asthma. Am J Vet Res. 2003 Nov; 64(11):1449-53. PMID: 14620784.
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    62. Giri SN, Al-Bayati MA, Du X, Schelegle E, Mohr FC, Margolin SB. Amelioration of doxorubicin-induced cardiac and renal toxicity by pirfenidone in rats. Cancer Chemother Pharmacol. 2004 Feb; 53(2):141-50. PMID: 14564477.
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    63. Schelegle E, Miller LA, Gershwin LJ, Fanucchi MV, Van Winkle LS, Gerriets JE, Walby WF, Mitchell V, Tarkington BK, Wong VJ, Baker GL, Pantle LM, Joad JP, Pinkerton KE, Wu R, Evans MJ, Hyde DM, Plopper CG. Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicol Appl Pharmacol. 2003 Aug 15; 191(1):74-85. PMID: 12915105.
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    64. Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle E, Gershwin LJ, Miller LA, Hyde DM, Sannes PL, Plopper CG. Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L931-9. PMID: 12832283.
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    65. Reader JR, Tepper JS, Schelegle E, Aldrich MC, Putney LF, Pfeiffer JW, Hyde DM. Pathogenesis of mucous cell metaplasia in a murine asthma model. Am J Pathol. 2003 Jun; 162(6):2069-78. PMID: 12759261; PMCID: PMC2216702.
    66. Reader JR, Hyde DM, Schelegle E, Aldrich MC, Stoddard AM, McLane MP, Levitt RC, Tepper JS. Interleukin-9 induces mucous cell metaplasia independent of inflammation. Am J Respir Cell Mol Biol. 2003 Jun; 28(6):664-72. PMID: 12760964.
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    67. Larson SD, Schelegle E, Hyde DM, Plopper CG. The three-dimensional distribution of nerves along the entire intrapulmonary airway tree of the adult rat and the anatomical relationship between nerves and neuroepithelial bodies. Am J Respir Cell Mol Biol. 2003 May; 28(5):592-9. PMID: 12707015.
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    68. Seymour BW, Schelegle E, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol. 2003 Mar; 10(1):35-42. PMID: 14575156; PMCID: PMC2270675.
    69. Miller LA, Hyde DM, Gershwin LJ, Schelegle E, Fanucchi MV, Evans MJ, Gerriets JE, Putney LF, Stovall MY, Tyler NK, Usachenko JL, Plopper CG. The effect of house dust mite aeroallergen and air pollutant exposures during infancy. Chest. 2003 Mar; 123(3 Suppl):434S. PMID: 12629026.
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    70. Schelegle E, Walby WF, Alfaro MF, Wong VJ, Putney L, Stovall MY, Sterner-Kock A, Hyde DM, Plopper CG. Repeated episodes of ozone inhalation attenuates airway injury/repair and release of substance P, but not adaptation. Toxicol Appl Pharmacol. 2003 Feb 01; 186(3):127-42. PMID: 12620366.
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    71. Schelegle E. Functional morphology and physiology of slowly adapting pulmonary stretch receptors. Anat Rec A Discov Mol Cell Evol Biol. 2003 Jan; 270(1):11-6. PMID: 12494485.
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    72. Plopper CG, Nishio SJ, Schelegle E. Tethering tracheobronchial airways within the lungs. Am J Respir Crit Care Med. 2003 Jan 01; 167(1):2-3. PMID: 12502468.
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    73. Evans MJ, Van Winkle LS, Fanucchi MV, Baker GL, Murphy AE, Nishio SJ, Schelegle E, Gershwin LJ, Sannes PL, Plopper CG. Fibroblast growth factor-2 in remodeling of the developing basement membrane zone in the trachea of infant rhesus monkeys sensitized and challenged with allergen. Lab Invest. 2002 Dec; 82(12):1747-54. PMID: 12480924.
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    74. Chen CY, Bonham AC, Schelegle E, Gershwin LJ, Plopper CG, Joad JP. Extended allergen exposure in asthmatic monkeys induces neuroplasticity in nucleus tractus solitarius. J Allergy Clin Immunol. 2001 Oct; 108(4):557-62. PMID: 11590381.
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    75. Schelegle E, Alfaro MF, Putney L, Stovall M, Tyler N, Hyde DM. Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats. J Appl Physiol (1985). 2001 Oct; 91(4):1611-8. PMID: 11568142.
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    76. Mansoor JK, Eldridge MW, Yoneda KY, Schelegle E, Wood SC. Role of airway receptors in altitude-induced dyspnea. Med Sci Sports Exerc. 2001 Sep; 33(9):1449-55. PMID: 11528331.
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    77. Schelegle E, Walby WF, Mansoor JK, Chen AT. Lung vagal afferent activity in rats with bleomycin-induced lung fibrosis. Respir Physiol. 2001 May; 126(1):9-27. PMID: 11311307.
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    78. Schelegle E, Eldridge MW, Cross CE, Walby WF, Adams WC. Differential effects of airway anesthesia on ozone-induced pulmonary responses in human subjects. Am J Respir Crit Care Med. 2001 Apr; 163(5):1121-7. PMID: 11316647.
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    79. Schelegle E, Green JF. An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors. Respir Physiol. 2001 Mar; 125(1-2):17-31. PMID: 11240150.
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    80. Schelegle E, Gershwin LJ, Miller LA, Fanucchi MV, Van Winkle LS, Gerriets JP, Walby WF, Omlor AM, Buckpitt AR, Tarkington BK, Wong VJ, Joad JP, Pinkerton KB, Wu R, Evans MJ, Hyde DM, Plopper CG. Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae). Am J Pathol. 2001 Jan; 158(1):333-41. PMID: 11141508; PMCID: PMC1850255.
    81. Postlethwait EM, Joad JP, Hyde DM, Schelegle E, Bric JM, Weir AJ, Putney LF, Wong VJ, Velsor LW, Plopper CG. Three-dimensional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):191-9. PMID: 10657940.
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    82. Schelegle E, Mansoor JK, Green JF. Interaction of vagal lung afferents with inhalation of histamine aerosol in anesthetized dogs. Lung. 2000; 178(1):41-52. PMID: 10723719.
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    83. Schelegle E, Chen AT, Loh CY. Effects of vagal perineural capsaicin treatment on vagal efferent and airway neurogenic responses in anesthetized rats. J Basic Clin Physiol Pharmacol. 2000; 11(1):1-16. PMID: 10851659.
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    84. Woolums AR, Anderson ML, Gunther RA, Schelegle E, LaRochelle DR, Singer RS, Boyle GA, Friebertshauser KE, Gershwin LJ. Evaluation of severe disease induced by aerosol inoculation of calves with bovine respiratory syncytial virus. Am J Vet Res. 1999 Apr; 60(4):473-80. PMID: 10211692.
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    85. Vesely KR, Schelegle E, Stovall MY, Harkema JR, Green JF, Hyde DM. Breathing pattern response and epithelial labeling in ozone-induced airway injury in neutrophil-depleted rats. Am J Respir Cell Mol Biol. 1999 Apr; 20(4):699-709. PMID: 10101002.
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    86. Vesely KR, Hyde DM, Stovall MY, Harkema JR, Green JF, Schelegle E. Capsaicin-sensitive C-fiber-mediated protective responses in ozone inhalation in rats. J Appl Physiol (1985). 1999 Mar; 86(3):951-62. PMID: 10066710.
      View in: PubMed
    87. Mansoor JK, Chen AT, Schelegle E, Giri S. Effect of diet-ingested pirfenidone on pulmonary function, cardiovasculature and blood gas measurements in rats. Res Commun Mol Pathol Pharmacol. 1999 Mar; 103(3):260-8. PMID: 10509737.
      View in: PubMed
    88. Carl ML, Schelegle E, Hollstien SB, Green JF. Control of ventilation during lung volume changes and permissive hypercapnia in dogs. Am J Respir Crit Care Med. 1998 Sep; 158(3):742-8. PMID: 9730999.
      View in: PubMed
    89. Gershwin LJ, Schelegle E, Gunther RA, Anderson ML, Woolums AR, Larochelle DR, Boyle GA, Friebertshauser KE, Singer RS. A bovine model of vaccine enhanced respiratory syncytial virus pathophysiology. Vaccine. 1998 Jul; 16(11-12):1225-36. PMID: 9682383.
      View in: PubMed
    90. Schelegle E, Mansoor JK, Giri S. Pirfenidone attenuates bleomycin-induced changes in pulmonary functions in hamsters. Proc Soc Exp Biol Med. 1997 Dec; 216(3):392-7. PMID: 9402144.
      View in: PubMed
    91. Mansoor JK, Hyde DM, Schelegle E. Contribution of vagal afferents to breathing pattern in rats with lung fibrosis. Respir Physiol. 1997 Apr; 108(1):45-61. PMID: 9178376.
      View in: PubMed
    92. Sterner-Kock A, Vesely KR, Stovall MY, Schelegle E, Green JF, Hyde DM. Neonatal capsaicin treatment increases the severity of ozone-induced lung injury. Am J Respir Crit Care Med. 1996 Jan; 153(1):436-43. PMID: 8542155.
      View in: PubMed
    93. Schelegle E, Mansoor JK, Green JF. Influence of background vagal C-fiber activity on eupneic breathing pattern in anesthetized dogs. J Appl Physiol (1985). 1995 Aug; 79(2):600-6. PMID: 7592224.
      View in: PubMed
    94. Carl ML, Rhee KJ, Schelegle E, Green JF. Effects of graded upper-airway obstruction on pulmonary mechanics during transtracheal jet ventilation in dogs. Ann Emerg Med. 1994 Dec; 24(6):1137-43. PMID: 7978596.
      View in: PubMed
    95. Carl ML, Rhee KJ, Schelegle E, Green JF. Pulmonary mechanics of dogs during transtracheal jet ventilation. Ann Emerg Med. 1994 Dec; 24(6):1126-36. PMID: 7978595.
      View in: PubMed
    96. Coleridge JC, Coleridge HM, Schelegle E, Green JF. Acute inhalation of ozone stimulates bronchial C-fibers and rapidly adapting receptors in dogs. J Appl Physiol (1985). 1993 May; 74(5):2345-52. PMID: 8335566.
      View in: PubMed
    97. Schelegle E, Carl ML, Coleridge HM, Coleridge JC, Green JF. Contribution of vagal afferents to respiratory reflexes evoked by acute inhalation of ozone in dogs. J Appl Physiol (1985). 1993 May; 74(5):2338-44. PMID: 8335565.
      View in: PubMed
    98. Gunther RA, Yousef MA, Schelegle E, Cross CE. Corticosteroid administration modifies ozone-induced increases in sheep airway blood flow. Am Rev Respir Dis. 1992 Sep; 146(3):660-4. PMID: 1519844.
      View in: PubMed
    99. Hollstien SB, Carl ML, Schelegle E, Green JF. Role of vagal afferents in the control of abdominal expiratory muscle activity in the dog. J Appl Physiol (1985). 1991 Nov; 71(5):1795-800. PMID: 1761476.
      View in: PubMed
    100. Schelegle E, Siefkin AD, McDonald RJ. Time course of ozone-induced neutrophilia in normal humans. Am Rev Respir Dis. 1991 Jun; 143(6):1353-8. PMID: 2048824.
      View in: PubMed
    101. Hornof WJ, Schelegle E, Kammerman M, Gunther RA, Fisher PE, Cross CE. Ozone-induced accelerated lung clearance of 99mTc-DTPA aerosol in conscious sheep. Respir Physiol. 1989 Sep; 77(3):277-90. PMID: 2506622.
      View in: PubMed
    102. Adams WC, Schelegle E, Shaffrath JD. Oral and oronasal breathing during continuous exercise produce similar responses to ozone inhalation. Arch Environ Health. 1989 Sep-Oct; 44(5):311-6. PMID: 2817961.
      View in: PubMed
    103. Schelegle E, Adams WC, Giri SN, Siefkin AD. Acute ozone exposure increases plasma prostaglandin F2 alpha in ozone-sensitive human subjects. Am Rev Respir Dis. 1989 Jul; 140(1):211-6. PMID: 2751167.
      View in: PubMed
    104. Schonfeld BR, Adams WC, Schelegle E. Duration of enhanced responsiveness upon re-exposure to ozone. Arch Environ Health. 1989 Jul-Aug; 44(4):229-36. PMID: 2782945.
      View in: PubMed
    105. Brookes KA, Adams WC, Schelegle E. O.35 ppm O3 exposure induces hyperresponsiveness on 24-h reexposure to 0.20 ppm O3. J Appl Physiol (1985). 1989 Jun; 66(6):2756-62. PMID: 2745339.
      View in: PubMed
    106. Schelegle E, Adams WC, Siefkin AD. Indomethacin pretreatment reduces ozone-induced pulmonary function decrements in human subjects. Am Rev Respir Dis. 1987 Dec; 136(6):1350-4. PMID: 3688637.
      View in: PubMed
    107. Adams WC, Brookes KA, Schelegle E. Effects of NO2 alone and in combination with O3 on young men and women. J Appl Physiol (1985). 1987 Apr; 62(4):1698-704. PMID: 3597241.
      View in: PubMed
    108. Schelegle E, Adams WC. Reduced exercise time in competitive simulations consequent to low level ozone exposure. Med Sci Sports Exerc. 1986 Aug; 18(4):408-14. PMID: 3747800.
      View in: PubMed
    109. Adams WC, Schelegle E. Ozone and high ventilation effects on pulmonary function and endurance performance. J Appl Physiol Respir Environ Exerc Physiol. 1983 Sep; 55(3):805-12. PMID: 6629918.
      View in: PubMed