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Frank R Sharp

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InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shroff N, Ander BP, Zhan X, Stamova B, Liu D, Hull H, Hamade FR, Dykstra-Aiello C, Ng K, Sharp F, Jickling GC. HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke. Transl Stroke Res. 2018 Apr 13. PMID: 29651704.
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    2. Ye Z, Ander BP, Sharp F, Zhan X. Cleaved ß-Actin May Contribute to DNA Fragmentation Following Very Brief Focal Cerebral Ischemia. J Neuropathol Exp Neurol. 2018 Mar 01; 77(3):260-265. PMID: 29408985.
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    3. Zhan X, Stamova B, Sharp F. Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer's Disease Brain: A Review. Front Aging Neurosci. 2018; 10:42. PMID: 29520228.
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    4. Stamova B, Ander BP, Jickling G, Hamade F, Durocher M, Zhan X, Liu DZ, Cheng X, Hull H, Yee A, Ng K, Shroff N, Sharp F. The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes. J Cereb Blood Flow Metab. 2018 Jan 01; 271678X18769513. PMID: 29651892.
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    5. Sun P, Liu DZ, Jickling GC, Sharp F, Yin KJ. MicroRNA-based therapeutics in central nervous system injuries. J Cereb Blood Flow Metab. 2018 Jan 01; 271678X18773871. PMID: 29708005.
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    6. Swor DE, Sharp F, Jickling GC. Clinical Reasoning: A case of altered mental status, not otherwise specified. Neurology. 2017 Sep 26; 89(13):e154-e158. PMID: 28947587.
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    7. Jauch EC, Barreto AD, Broderick JP, Char DM, Cucchiara BL, Devlin TG, Haddock AJ, Hicks WJ, Hiestand BC, Jickling GC, June J, Liebeskind DS, Lowenkopf TJ, Miller JB, O'Neill J, Schoonover TL, Sharp F, Peacock WF. Biomarkers of Acute Stroke Etiology (BASE) Study Methodology. Transl Stroke Res. 2017 May 05. PMID: 28477280.
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    8. Schumann CM, Sharp F, Ander BP, Stamova B. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. Mol Autism. 2017; 8:4. PMID: 28184278.
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    9. Tylee DS, Hess JL, Quinn TP, Barve R, Huang H, Zhang-James Y, Chang J, Stamova BS, Sharp F, Hertz-Picciotto I, Faraone SV, Kong SW, Glatt SJ. Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 174(3):181-201. PMID: 27862943.
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    10. Dykstra-Aiello C, Jickling GC, Ander BP, Shroff N, Zhan X, Liu D, Hull H, Orantia M, Stamova BS, Sharp F. Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci. Stroke. 2016 12; 47(12):2896-2903. PMID: 27834745.
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    11. Jickling GC, Ander BP, Shroff N, Orantia M, Stamova B, Dykstra-Aiello C, Hull H, Zhan X, Liu D, Sharp F. Leukocyte response is regulated by microRNA let7i in patients with acute ischemic stroke. Neurology. 2016 Nov 22; 87(21):2198-2205. PMID: 27784773.
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    12. Zhan X, Stamova B, Jin LW, DeCarli C, Phinney B, Sharp F. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016 Nov 29; 87(22):2324-2332. PMID: 27784770.
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    13. Turner RJ, Sharp F. Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke. Front Cell Neurosci. 2016; 10:56. PMID: 26973468; PMCID: PMC4777722.
    14. Liu DZ, Waldau B, Ander BP, Zhan X, Stamova B, Jickling GC, Lyeth BG, Sharp F. Inhibition of Src family kinases improves cognitive function after intraventricular hemorrhage or intraventricular thrombin. J Cereb Blood Flow Metab. 2017 Jul; 37(7):2359-2367. PMID: 27624844.
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    15. Liu da Z, Jickling GC, Ander BP, Hull H, Zhan X, Cox C, Shroff N, Dykstra-Aiello C, Stamova B, Sharp F. Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab. 2016 Aug; 36(8):1374-83. PMID: 26661204; PMCID: PMC4976655.
    16. Liu DZ, Stamova B, Hu S, Ander BP, Jickling GC, Zhan X, Sharp F, Wong B. MicroRNA and mRNA Expression Changes in Steroid Naïve and Steroid Treated DMD Patients. J Neuromuscul Dis. 2015 Sep 22; 2(4):387-396. PMID: 27858746.
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    17. Stamova B, Ander BP, Barger N, Sharp F, Schumann CM. Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains. J Child Neurol. 2015 Dec; 30(14):1930-46. PMID: 26350727; PMCID: PMC4647182.
    18. Ander BP, Barger N, Stamova B, Sharp F, Schumann CM. Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. Mol Autism. 2015; 6:37. PMID: 26146533; PMCID: PMC4491207.
    19. Jickling GC, Liu D, Ander BP, Stamova B, Zhan X, Sharp F. Targeting neutrophils in ischemic stroke: translational insights from experimental studies. J Cereb Blood Flow Metab. 2015 Jun; 35(6):888-901. PMID: 25806703; PMCID: PMC4640255.
    20. Jickling GC, Sharp F. Biomarker panels in ischemic stroke. Stroke. 2015 Mar; 46(3):915-20. PMID: 25657186; PMCID: PMC4342265.
    21. Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp F. Myelin basic protein associates with AßPP, Aß1-42, and amyloid plaques in cortex of Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(4):1213-29. PMID: 25697841; PMCID: PMC4422390.
    22. Zhan X, Cox C, Ander BP, Liu D, Stamova B, Jin LW, Jickling GC, Sharp F. Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-ß and AßPP in Adult Rat Brain. J Alzheimers Dis. 2015; 46(2):507-23. PMID: 25790832; PMCID: PMC4878315.
    23. Sellier C, Hwang VJ, Dandekar R, Durbin-Johnson B, Charlet-Berguerand N, Ander BP, Sharp F, Angkustsiri K, Simon TJ, Tassone F. Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. PLoS One. 2014; 9(8):e103884. PMID: 25084529; PMCID: PMC4118991.
    24. Sharp F, Jickling GC. Modeling immunity and inflammation in stroke: differences between rodents and humans? Stroke. 2014 Sep; 45(9):e179-80. PMID: 25061082.
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    25. Stamova B, Jickling GC, Ander BP, Zhan X, Liu D, Turner R, Ho C, Khoury JC, Bushnell C, Pancioli A, Jauch EC, Broderick JP, Sharp F. Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic. PLoS One. 2014; 9(7):e102550. PMID: 25036109; PMCID: PMC4103830.
    26. Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp F. Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):226-33. PMID: 24731980; PMCID: PMC4139468.
    27. Liu DZ, Sharp F, Van KC, Ander BP, Ghiasvand R, Zhan X, Stamova B, Jickling GC, Lyeth BG. Inhibition of SRC family kinases protects hippocampal neurons and improves cognitive function after traumatic brain injury. J Neurotrauma. 2014 Jul 15; 31(14):1268-76. PMID: 24428562; PMCID: PMC4108941.
    28. Zhan X, Jickling GC, Ander BP, Liu D, Stamova B, Cox C, Jin LW, DeCarli C, Sharp F. Myelin injury and degraded myelin vesicles in Alzheimer's disease. Curr Alzheimer Res. 2014 Mar; 11(3):232-8. PMID: 24484278; PMCID: PMC4066812.
    29. Jickling GC, Sharp F. Improving the translation of animal ischemic stroke studies to humans. Metab Brain Dis. 2015 Apr; 30(2):461-7. PMID: 24526567; PMCID: PMC4186910.
    30. Jickling GC, Liu D, Stamova B, Ander BP, Zhan X, Lu A, Sharp F. Hemorrhagic transformation after ischemic stroke in animals and humans. J Cereb Blood Flow Metab. 2014 Feb; 34(2):185-99. PMID: 24281743; PMCID: PMC3915212.
    31. Jickling GC, Ander BP, Stamova B, Zhan X, Liu D, Rothstein L, Verro P, Khoury J, Jauch EC, Pancioli AM, Broderick JP, Sharp F. RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke. Ann Neurol. 2013 Aug; 74(2):232-40. PMID: 23468366; PMCID: PMC3752310.
    32. Stamova BS, Tian Y, Nordahl CW, Shen MD, Rogers S, Amaral DG, Sharp F. Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders. Mol Autism. 2013 Sep 04; 4(1):30. PMID: 24007566; PMCID: PMC3846739.
    33. Sharp F, Zhan X, Liu DZ. Heat shock proteins in the brain: role of Hsp70, Hsp 27, and HO-1 (Hsp32) and their therapeutic potential. Transl Stroke Res. 2013 Dec; 4(6):685-92. PMID: 24323422; PMCID: PMC3858824.
    34. Peng B, Zhu D, Ander BP, Zhang X, Xue F, Sharp F, Yang X. An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways. PLoS One. 2013; 8(7):e67672. PMID: 23844055.
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    35. Sharp F, Jickling GC. Whole genome expression of cellular response to stroke. Stroke. 2013 Jun; 44(6 Suppl 1):S23-5. PMID: 23709718.
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    36. Cox C, Sharp F. RNA-based blood genomics as an investigative tool and prospective biomarker for ischemic stroke. Neurol Res. 2013 Jun; 35(5):457-64. PMID: 23635721.
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    37. Apperson ML, Tian Y, Stamova B, Ander BP, Jickling GC, Agius MA, Sharp F. Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study. J Neuroimmunol. 2013 Apr 15; 257(1-2):90-6. PMID: 23477965.
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    38. Paschou P, Fernandez TV, Sharp F, Heiman GA, Hoekstra PJ. Genetic susceptibility and neurotransmitters in Tourette syndrome. Int Rev Neurobiol. 2013; 112:155-77. PMID: 24295621; PMCID: PMC4471172.
    39. Tian Y, Stamova B, Ander BP, Jickling GC, Gunther JR, Corbett BA, Bos-Veneman NG, Hoekstra PJ, Schweitzer JB, Sharp F. Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study. BMC Med Genomics. 2012 Oct 30; 5:49. PMID: 23110997.
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    40. Gunther J, Tian Y, Stamova B, Lit L, Corbett B, Ander B, Zhan X, Jickling G, Bos-Veneman N, Liu D, Hoekstra P, Sharp F. Catecholamine-related gene expression in blood correlates with tic severity in tourette syndrome. Psychiatry Res. 2012 Dec 30; 200(2-3):593-601. PMID: 22648010.
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    41. Jickling GC, Stamova B, Ander BP, Zhan X, Liu D, Sison SM, Verro P, Sharp F. Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location. Stroke. 2012 Aug; 43(8):2036-41. PMID: 22627989.
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    42. Liu DZ, Sharp F. Excitatory and Mitogenic Signaling in Cell Death, Blood-brain Barrier Breakdown, and BBB Repair after Intracerebral Hemorrhage. Transl Stroke Res. 2012 Jul; 3(Suppl 1):62-9. PMID: 24323862.
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    43. Tian Y, Stamova B, Jickling GC, Xu H, Liu D, Ander BP, Bushnell C, Zhan X, Turner RJ, Davis RR, Verro P, Pevec WC, Hedayati N, Dawson DL, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp F. Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls. Gend Med. 2012 Apr; 9(2):68-75.e3. PMID: 22365286; PMCID: PMC3454519.
    44. Jickling GC, Zhan X, Stamova B, Ander BP, Tian Y, Liu D, Sison SM, Verro P, Johnston SC, Sharp F. Ischemic transient neurological events identified by immune response to cerebral ischemia. Stroke. 2012 Apr; 43(4):1006-12. PMID: 22308247; PMCID: PMC3327404.
    45. Liu DZ, Ander BP, Tian Y, Stamova B, Jickling GC, Davis RR, Sharp F. Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells. Gene. 2012 Mar 10; 495(2):120-7. PMID: 22244746.
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    46. Tian Y, Stamova B, Jickling GC, Liu D, Ander BP, Bushnell C, Zhan X, Davis RR, Verro P, Pevec WC, Hedayati N, Dawson DL, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp F. Effects of gender on gene expression in the blood of ischemic stroke patients. J Cereb Blood Flow Metab. 2012 May; 32(5):780-91. PMID: 22167233; PMCID: PMC3345909.
    47. Weinsheimer SM, Xu H, Achrol AS, Stamova B, McCulloch CE, Pawlikowska L, Tian Y, Ko NU, Lawton MT, Steinberg GK, Chang SD, Jickling G, Ander BP, Kim H, Sharp F, Young WL. Gene expression profiling of blood in brain arteriovenous malformation patients. Transl Stroke Res. 2011 Dec 01; 2(4):575-87. PMID: 22184505; PMCID: PMC3241209.
    48. Stamova B, Tian Y, Jickling G, Bushnell C, Zhan X, Liu D, Ander BP, Verro P, Patel V, Pevec WC, Hedayati N, Dawson DL, Jauch EC, Pancioli A, Broderick JP, Sharp F. The X-chromosome has a different pattern of gene expression in women compared with men with ischemic stroke. Stroke. 2012 Feb; 43(2):326-34. PMID: 22052522; PMCID: PMC3938328.
    49. Xu H, Lu A, Sharp F. Regional genome transcriptional response of adult mouse brain to hypoxia. BMC Genomics. 2011 Oct 11; 12:499. PMID: 21988864; PMCID: PMC3218040.
    50. Jickling GC, Stamova B, Ander BP, Zhan X, Tian Y, Liu D, Xu H, Johnston SC, Verro P, Sharp F. Profiles of lacunar and nonlacunar stroke. Ann Neurol. 2011 Sep; 70(3):477-85. PMID: 21796664.
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    51. del Zoppo GJ, Sharp F, Heiss WD, Albers GW. Heterogeneity in the penumbra. J Cereb Blood Flow Metab. 2011 Sep; 31(9):1836-51. PMID: 21731034; PMCID: PMC3185890.
    52. Jickling GC, Sharp F. Blood biomarkers of ischemic stroke. Neurotherapeutics. 2011 Jul; 8(3):349-60. PMID: 21671123; PMCID: PMC3250275.
    53. Sharp F, Jickling GC, Stamova B, Tian Y, Zhan X, Ander BP, Cox C, Kuczynski B, Liu D. RNA expression profiles from blood for the diagnosis of stroke and its causes. J Child Neurol. 2011 Sep; 26(9):1131-6. PMID: 21636778; PMCID: PMC3674558.
    54. Turner RJ, Bushnell CD, Register TC, Sharp F. Gender-dependent correlations of carotid intima-media thickness with gene expression in blood. Transl Stroke Res. 2011 Jun; 2(2):171-8. PMID: 22287995; PMCID: PMC3266847.
    55. Sharp F, Jickling GC, Stamova B, Tian Y, Zhan X, Liu D, Kuczynski B, Cox CD, Ander BP. Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humans. J Cereb Blood Flow Metab. 2011 Jul; 31(7):1513-31. PMID: 21505474; PMCID: PMC3137473.
    56. Neuwelt EA, Bauer B, Fahlke C, Fricker G, Iadecola C, Janigro D, Leybaert L, Molnár Z, O'Donnell ME, Povlishock JT, Saunders NR, Sharp F, Stanimirovic D, Watts RJ, Drewes LR. Engaging neuroscience to advance translational research in brain barrier biology. Nat Rev Neurosci. 2011 Mar; 12(3):169-82. PMID: 21331083; PMCID: PMC3335275.
    57. Zhan X, Kuczynski B, Sharp F. Post stroke intervention: is the window widening? Neuropharmacology. 2011 May; 60(6):1000-2. PMID: 21315742.
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    58. Turner RJ, Jickling GC, Sharp F. Are Underlying Assumptions of Current Animal Models of Human Stroke Correct: from STAIRs to High Hurdles? Transl Stroke Res. 2011 Jun; 2(2):138-43. PMID: 21654913.
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    59. Tian Y, Gunther JR, Liao IH, Liu D, Ander BP, Stamova BS, Lit L, Jickling GC, Xu H, Zhan X, Sharp F. GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study. Brain Res. 2011 Mar 24; 1381:228-36. PMID: 21241679.
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    60. Tian Y, Apperson ML, Ander BP, Liu D, Stomova BS, Jickling GC, Enriquez R, Agius MA, Sharp F. Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjects. J Neuroimmunol. 2011 Jan; 230(1-2):124-9. PMID: 20920832.
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    61. Liu DZ, Sharp F. The dual role of SRC kinases in intracerebral hemorrhage. Acta Neurochir Suppl. 2011; 111:77-81. PMID: 21725735.
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    62. Liao IH, Corbett BA, Gilbert DL, Bunge SA, Sharp F. Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome. Pharmacogenomics. 2010 Dec; 11(12):1733-41. PMID: 21142917.
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    63. Tian Y, Liao IH, Zhan X, Gunther JR, Ander BP, Liu D, Lit L, Jickling GC, Corbett BA, Bos-Veneman NG, Hoekstra PJ, Sharp F. Exon expression and alternatively spliced genes in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan; 156B(1):72-8. PMID: 21184586; PMCID: PMC3070201.
    64. Jickling GC, Xu H, Stamova B, Ander BP, Zhan X, Tian Y, Liu D, Turner RJ, Mesias M, Verro P, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp F. Signatures of cardioembolic and large-vessel ischemic stroke. Ann Neurol. 2010 Nov; 68(5):681-92. PMID: 21031583.
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    65. Xu H, Stamova B, Jickling G, Tian Y, Zhan X, Ander BP, Liu D, Turner R, Rosand J, Goldstein LB, Furie KL, Verro P, Johnston SC, Sharp F, Decarli CS. Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. Stroke. 2010 Dec; 41(12):2744-9. PMID: 20966416.
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    66. Sharp F. Where do omics and markers go next? Transl Stroke Res. 2010 Dec; 1(4):231-2. PMID: 21170137.
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    67. Stamova B, Xu H, Jickling G, Bushnell C, Tian Y, Ander BP, Zhan X, Liu D, Turner R, Adamczyk P, Khoury JC, Pancioli A, Jauch E, Broderick JP, Sharp F. Gene expression profiling of blood for the prediction of ischemic stroke. Stroke. 2010 Oct; 41(10):2171-7. PMID: 20798371; PMCID: PMC2987675.
    68. Liao IH, Sharp F. Tourette syndrome: gene expression as a tool to discover drug targets. Neurotherapeutics. 2010 Jul; 7(3):302-6. PMID: 20643383.
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    69. Jickling GC, Zhan X, Ander BP, Turner RJ, Stamova B, Xu H, Tian Y, Liu D, Davis RR, Lapchak PA, Sharp F. Genome response to tissue plasminogen activator in experimental ischemic stroke. BMC Genomics. 2010 Apr 21; 11:254. PMID: 20406488; PMCID: PMC2875237.
    70. Liu DZ, Ander BP, Xu H, Shen Y, Kaur P, Deng W, Sharp F. Blood-brain barrier breakdown and repair by Src after thrombin-induced injury. Ann Neurol. 2010 Apr; 67(4):526-33. PMID: 20437588; PMCID: PMC2919346.
    71. Zhan X, Ander BP, Liao IH, Hansen JE, Kim C, Clements D, Weisbart RH, Nishimura RN, Sharp F. Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats. Stroke. 2010 Mar; 41(3):538-43. PMID: 20075343; PMCID: PMC2957177.
    72. Liu DZ, Ander BP, Sharp F. Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of central nervous system diseases. Neurobiol Dis. 2010 Mar; 37(3):549-57. PMID: 19944161; PMCID: PMC2823995.
    73. Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp F. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotox Res. 2011 Jan; 19(1):31-48. PMID: 19937285.
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    74. Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp F. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotox Res. 2011 Jan; 19(1):1-13. PMID: 19921347; PMCID: PMC3006638.
    75. Liu DZ, Ander BP, Sharp F. WITHDRAWN: Cell cycle Inhibition as a Strategy for Treatment of Central Nervous System Diseases. Recent Pat Nanotechnol. 2009 Nov 01. PMID: 19534699.
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    76. Zhan X, Ander BP, Jickling G, Turner R, Stamova B, Xu H, Liu D, Davis RR, Sharp F. Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood. J Cereb Blood Flow Metab. 2010 Jan; 30(1):110-8. PMID: 19738631; PMCID: PMC2949112.
    77. Liu DZ, Tian Y, Ander BP, Xu H, Stamova BS, Zhan X, Turner RJ, Jickling G, Sharp F. Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J Cereb Blood Flow Metab. 2010 Jan; 30(1):92-101. PMID: 19724284; PMCID: PMC2949089.
    78. Stamova BS, Apperson M, Walker WL, Tian Y, Xu H, Adamczy P, Zhan X, Liu DZ, Ander BP, Liao IH, Gregg JP, Turner RJ, Jickling G, Lit L, Sharp F. Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood. BMC Med Genomics. 2009 Aug 05; 2:49. PMID: 19656400; PMCID: PMC2736983.
    79. Hendren RL, Bertoglio K, Ashwood P, Sharp F. Mechanistic biomarkers for autism treatment. Med Hypotheses. 2009 Dec; 73(6):950-4. PMID: 19619951.
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    80. Lu A, Clark JF, Broderick JP, Pyne-Geithman GJ, Wagner KR, Khatri P, Tomsick T, Sharp F. Mechanical reperfusion is associated with post-ischemic hemorrhage in rat brain. Exp Neurol. 2009 Apr; 216(2):407-12. PMID: 19162014; PMCID: PMC2659349.
    81. Wong B, Gilbert DL, Walker WL, Liao IH, Lit L, Stamova B, Jickling G, Apperson M, Sharp F. Gene expression in blood of subjects with Duchenne muscular dystrophy. Neurogenetics. 2009 Apr; 10(2):117-25. PMID: 19067001.
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    82. Lu A, Clark JF, Ran R, Pyne-Geithman G, Wagner KR, Millhorn DE, Sharp F. Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent. Neurol Res. 2009 Jun; 31(5):545-9. PMID: 19055876.
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    83. Walker WL, Liao IH, Gilbert DL, Wong B, Pollard KS, McCulloch CE, Lit L, Sharp F. Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients. BMC Genomics. 2008 Oct 20; 9:494. PMID: 18937867; PMCID: PMC2576259.
    84. Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp F, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain Behav Immun. 2009 Jan; 23(1):124-33. PMID: 18762240; PMCID: PMC2636576.
    85. Zhan X, Kim C, Sharp F. Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein. Brain Res. 2008 Oct 09; 1234:183-97. PMID: 18708034; PMCID: PMC2670998.
    86. Lit L, Enstrom A, Sharp F, Gilbert DL. Age-related gene expression in Tourette syndrome. J Psychiatr Res. 2009 Jan; 43(3):319-30. PMID: 18485367; PMCID: PMC2662336.
    87. Xu H, Tang Y, Liu DZ, Ran R, Ander BP, Apperson M, Liu XS, Khoury JC, Gregg JP, Pancioli A, Jauch EC, Wagner KR, Verro P, Broderick JP, Sharp F. Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke. J Cereb Blood Flow Metab. 2008 Jul; 28(7):1320-8. PMID: 18382470.
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    88. Liu DZ, Cheng XY, Ander BP, Xu H, Davis RR, Gregg JP, Sharp F. Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons. Neurobiol Dis. 2008 May; 30(2):201-11. PMID: 18343677; PMCID: PMC2413433.
    89. Lu A, Clark JF, Broderick JP, Pyne-Geithman GJ, Wagner KR, Ran R, Khatri P, Tomsick T, Sharp F. Reperfusion activates metalloproteinases that contribute to neurovascular injury. Exp Neurol. 2008 Apr; 210(2):549-59. PMID: 18187134; PMCID: PMC2588410.
    90. Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp F. Gene expression changes in children with autism. Genomics. 2008 Jan; 91(1):22-9. PMID: 18006270.
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    91. Lit L, Gilbert DL, Walker W, Sharp F. A subgroup of Tourette's patients overexpress specific natural killer cell genes in blood: a preliminary report. Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 05; 144B(7):958-63. PMID: 17503477.
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    92. Ran R, Pan R, Lu A, Xu H, Davis RR, Sharp F. A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis. Mol Cell Neurosci. 2007 Nov; 36(3):392-407. PMID: 17888676.
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    93. Sharp F, Hendren RL. Psychosis: atypical limbic epilepsy versus limbic hyperexcitability with onset at puberty? Epilepsy Behav. 2007 Jun; 10(4):515-20. PMID: 17416210; PMCID: PMC2680611.
    94. Ardizzone TD, Zhan X, Ander BP, Sharp F. SRC kinase inhibition improves acute outcomes after experimental intracerebral hemorrhage. Stroke. 2007 May; 38(5):1621-5. PMID: 17395859.
      View in: PubMed
    95. Sharp F, Xu H, Lit L, Walker W, Pinter J, Apperson M, Verro P. Genomic profiles of stroke in blood. Stroke. 2007 Feb; 38(2 Suppl):691-3. PMID: 17261717.
      View in: PubMed
    96. Sharp F, Xu H, Lit L, Walker W, Apperson M, Gilbert DL, Glauser TA, Wong B, Hershey A, Liu DZ, Pinter J, Zhan X, Liu X, Ran R. The future of genomic profiling of neurological diseases using blood. Arch Neurol. 2006 Nov; 63(11):1529-36. PMID: 17101821.
      View in: PubMed
    97. Sharp F, Lit L, Xu H, Apperson M, Walker W, Wong B, Gilbert DL, Hershey A, Glauser TA. Genomics of brain and blood: progress and pitfalls. Epilepsia. 2006 Oct; 47(10):1603-7. PMID: 17054680.
      View in: PubMed
    98. Adhami F, Liao G, Morozov YM, Schloemer A, Schmithorst VJ, Lorenz JN, Dunn RS, Vorhees CV, Wills-Karp M, Degen JL, Davis RJ, Mizushima N, Rakic P, Dardzinski BJ, Holland SK, Sharp F, Kuan CY. Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol. 2006 Aug; 169(2):566-83. PMID: 16877357; PMCID: PMC1780162.
    99. Pritchard LM, Logue AD, Taylor BC, Ahlbrand R, Welge JA, Tang Y, Sharp F, Richtand NM. Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty. Brain Res Bull. 2006 Oct 16; 70(4-6):296-303. PMID: 17027765; PMCID: PMC1815377.
    100. Vexler ZS, Sharp F, Feuerstein GZ, Ashwal S, Thoresen M, Yager JY, Ferriero DM. Translational stroke research in the developing brain. Pediatr Neurol. 2006 Jun; 34(6):459-63. PMID: 16765824.
      View in: PubMed
    101. Du X, Tang Y, Xu H, Lit L, Walker W, Ashwood P, Gregg JP, Sharp F. Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome. Genomics. 2006 Jun; 87(6):693-703. PMID: 16546348.
      View in: PubMed
    102. Clark JF, Sharp F. Bilirubin oxidation products (BOXes) and their role in cerebral vasospasm after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2006 Oct; 26(10):1223-33. PMID: 16467784.
      View in: PubMed
    103. Lu A, Tang Y, Ran R, Ardizzone TL, Wagner KR, Sharp F. Brain genomics of intracerebral hemorrhage. J Cereb Blood Flow Metab. 2006 Feb; 26(2):230-52. PMID: 16034371.
      View in: PubMed
    104. Tang Y, Xu H, Du X, Lit L, Walker W, Lu A, Ran R, Gregg JP, Reilly M, Pancioli A, Khoury JC, Sauerbeck LR, Carrozzella JA, Spilker J, Clark J, Wagner KR, Jauch EC, Chang DJ, Verro P, Broderick JP, Sharp F. Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J Cereb Blood Flow Metab. 2006 Aug; 26(8):1089-102. PMID: 16395289.
      View in: PubMed
    105. Nishimura RN, Sharp F. Heat shock proteins and neuromuscular disease. Muscle Nerve. 2005 Dec; 32(6):693-709. PMID: 15962334.
      View in: PubMed
    106. Dickerson J, Sharp F. Atypical antipsychotics and a Src kinase inhibitor (PP1) prevent cortical injury produced by the psychomimetic, noncompetitive NMDA receptor antagonist MK-801. Neuropsychopharmacology. 2006 Jul; 31(7):1420-30. PMID: 16123741.
      View in: PubMed
    107. Zhang D, Zhang L, Tang Y, Zhang Q, Lou D, Sharp F, Zhang J, Xu M. Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology. 2005 Aug; 30(8):1443-54. PMID: 15770241.
      View in: PubMed
    108. Ran R, Xu H, Lu A, Bernaudin M, Sharp F. Hypoxia preconditioning in the brain. Dev Neurosci. 2005 Mar-Aug; 27(2-4):87-92. PMID: 16046841.
      View in: PubMed
    109. Tang Y, Gilbert DL, Glauser TA, Hershey AD, Sharp F. Blood gene expression profiling of neurologic diseases: a pilot microarray study. Arch Neurol. 2005 Feb; 62(2):210-5. PMID: 15710849.
      View in: PubMed
    110. Tang Y, Lu A, Ran R, Aronow BJ, Schorry EK, Hopkin RJ, Gilbert DL, Glauser TA, Hershey AD, Richtand NW, Privitera M, Dalvi A, Sahay A, Szaflarski JP, Ficker DM, Ratner N, Sharp F. Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1. Brain Res Mol Brain Res. 2004 Dec 20; 132(2):155-67. PMID: 15582155.
      View in: PubMed
    111. Carter K, Dickerson J, Schoepp DD, Reilly M, Herring N, Williams J, Sallee FR, Sharp JW, Sharp F. The mGlu2/3 receptor agonist LY379268 injected into cortex or thalamus decreases neuronal injury in retrosplenial cortex produced by NMDA receptor antagonist MK-801: possible implications for psychosis. Neuropharmacology. 2004 Dec; 47(8):1135-45. PMID: 15567423.
      View in: PubMed
    112. Tang Y, Schapiro MB, Franz DN, Patterson BJ, Hickey FJ, Schorry EK, Hopkin RJ, Wylie M, Narayan T, Glauser TA, Gilbert DL, Hershey AD, Sharp F. Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and Down's syndrome. Ann Neurol. 2004 Dec; 56(6):808-14. PMID: 15562430.
      View in: PubMed
    113. Glass TF, Reeves B, Sharp F. The impact of excitotoxic blockade on the evolution of injury following combined mechanical and hypoxic insults in primary rat neuronal culture. Neurobiol Dis. 2004 Dec; 17(3):378-84. PMID: 15571974.
      View in: PubMed
    114. Kuan CY, Schloemer AJ, Lu A, Burns KA, Weng WL, Williams MT, Strauss KI, Vorhees CV, Flavell RA, Davis RJ, Sharp F, Rakic P. Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci. 2004 Nov 24; 24(47):10763-72. PMID: 15564594; PMCID: PMC2590933.
    115. Hershey AD, Tang Y, Powers SW, Kabbouche MA, Gilbert DL, Glauser TA, Sharp F. Genomic abnormalities in patients with migraine and chronic migraine: preliminary blood gene expression suggests platelet abnormalities. Headache. 2004 Nov-Dec; 44(10):994-1004. PMID: 15546262.
      View in: PubMed
    116. Weinstein PR, Hong S, Sharp F. Molecular identification of the ischemic penumbra. Stroke. 2004 Nov; 35(11 Suppl 1):2666-70. PMID: 15486332.
      View in: PubMed
    117. Ardizzone TD, Lu A, Wagner KR, Tang Y, Ran R, Sharp F. Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat. Stroke. 2004 Nov; 35(11):2587-91. PMID: 15375303.
      View in: PubMed
    118. Kim YS, Honkaniemi J, Sharp F, Täuber MG. Expression of proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta in the brain during experimental group B streptococcal meningitis. Brain Res Mol Brain Res. 2004 Sep 10; 128(1):95-102. PMID: 15337322.
      View in: PubMed
    119. Yamauchi T, Lin Y, Sharp F, Noble-Haeusslein LJ. Hemin induces heme oxygenase-1 in spinal cord vasculature and attenuates barrier disruption and neutrophil infiltration in the injured murine spinal cord. J Neurotrauma. 2004 Aug; 21(8):1017-30. PMID: 15319001.
      View in: PubMed
    120. Ran R, Lu A, Zhang L, Tang Y, Zhu H, Xu H, Feng Y, Han C, Zhou G, Rigby AC, Sharp F. Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling. Genes Dev. 2004 Jun 15; 18(12):1466-81. PMID: 15198984; PMCID: PMC423196.
    121. Sharp F, Bernaudin M. HIF1 and oxygen sensing in the brain. Nat Rev Neurosci. 2004 Jun; 5(6):437-48. PMID: 15152194.
      View in: PubMed
    122. Kalkkila JP, Sharp F, Kärkkäinen I, Reilly M, Lu A, Solway K, Murrel M, Honkaniemi J. Cloning and expression of short interspersed elements B1 and B2 in ischemic brain. Eur J Neurosci. 2004 Mar; 19(5):1199-206. PMID: 15016078.
      View in: PubMed
    123. Bernaudin M, Sharp F. Methods to detect hypoxia-induced ischemic tolerance in the brain. Methods Enzymol. 2004; 381:399-416. PMID: 15063689.
      View in: PubMed
    124. Ran R, Zhou G, Lu A, Zhang L, Tang Y, Rigby AC, Sharp F. Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival. Cell Stress Chaperones. 2004; 9(3):229-42. PMID: 15544161; PMCID: PMC1065282.
    125. Sharp F, Ran R, Lu A, Tang Y, Strauss KI, Glass T, Ardizzone T, Bernaudin M. Hypoxic preconditioning protects against ischemic brain injury. NeuroRx. 2004 Jan; 1(1):26-35. PMID: 15717005.
      View in: PubMed
    126. Kokubo Y, Liu J, Rajdev S, Kayama T, Sharp F, Weinstein PR. Differential cerebral protein synthesis and heat shock protein 70 expression in the core and penumbra of rat brain after transient focal ischemia. Neurosurgery. 2003 Jul; 53(1):186-90; discussion 190-1. PMID: 12823888.
      View in: PubMed
    127. Lu A, Tang Y, Ran R, Clark JF, Aronow BJ, Sharp F. Genomics of the periinfarction cortex after focal cerebral ischemia. J Cereb Blood Flow Metab. 2003 Jul; 23(7):786-810. PMID: 12843783.
      View in: PubMed
    128. Wagner KR, Sharp F, Ardizzone TD, Lu A, Clark JF. Heme and iron metabolism: role in cerebral hemorrhage. J Cereb Blood Flow Metab. 2003 Jun; 23(6):629-52. PMID: 12796711.
      View in: PubMed
    129. Chang EF, Wong RJ, Vreman HJ, Igarashi T, Galo E, Sharp F, Stevenson DK, Noble-Haeusslein LJ. Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury. J Neurosci. 2003 May 01; 23(9):3689-96. PMID: 12736340.
      View in: PubMed
    130. Tang Y, Nee AC, Lu A, Ran R, Sharp F. Blood genomic expression profile for neuronal injury. J Cereb Blood Flow Metab. 2003 Mar; 23(3):310-9. PMID: 12621306.
      View in: PubMed
    131. Mancuso A, Derugin N, Hara K, Marsh TA, Kong D, Sharp F, Weinstein PR. Cyclooxygenase-2 mRNA expression is associated with c-fos mRNA expression and transient water ADC reduction detected with diffusion MRI during acute focal ischemia in rats. Brain Res. 2003 Jan 24; 961(1):121-30. PMID: 12535784.
      View in: PubMed
    132. Glass TF, Reeves B, Sharp F. Modeling both the mechanical and hypoxic features of traumatic brain injury in vitro in rats. Neurosci Lett. 2002 Aug 09; 328(2):133-6. PMID: 12133573.
      View in: PubMed
    133. Bernaudin M, Tang Y, Reilly M, Petit E, Sharp F. Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J Biol Chem. 2002 Oct 18; 277(42):39728-38. PMID: 12145288.
      View in: PubMed
    134. Cao G, Pei W, Ge H, Liang Q, Luo Y, Sharp F, Lu A, Ran R, Graham SH, Chen J. In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis. J Neurosci. 2002 Jul 01; 22(13):5423-31. PMID: 12097494.
      View in: PubMed
    135. Tang Y, Lu A, Aronow BJ, Wagner KR, Sharp F. Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur J Neurosci. 2002 Jun; 15(12):1937-52. PMID: 12099900.
      View in: PubMed
    136. Kokubo Y, Matson GB, Liu J, Mancuso A, Kayama T, Sharp F, Weinstein PR. Correlation between changes in apparent diffusion coefficient and induction of heat shock protein, cell-specific injury marker expression, and protein synthesis reduction on diffusion-weighted magnetic resonance images after temporary focal cerebral ischemia in rats. J Neurosurg. 2002 Jun; 96(6):1084-93. PMID: 12066911.
      View in: PubMed
    137. Lu A, Ran R, Parmentier-Batteur S, Nee A, Sharp F. Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia. J Neurochem. 2002 Apr; 81(2):355-64. PMID: 12064483.
      View in: PubMed
    138. Clark JF, Reilly M, Sharp F. Oxidation of bilirubin produces compounds that cause prolonged vasospasm of rat cerebral vessels: a contributor to subarachnoid hemorrhage-induced vasospasm. J Cereb Blood Flow Metab. 2002 Apr; 22(4):472-8. PMID: 11919518.
      View in: PubMed
    139. Sharp F, Liu J, Bernabeu R. Neurogenesis following brain ischemia. Brain Res Dev Brain Res. 2002 Mar 31; 134(1-2):23-30. PMID: 11947934.
      View in: PubMed
    140. Murphy P, Sharp A, Shin J, Gavrilyuk V, Dello Russo C, Weinberg G, Sharp F, Lu A, Heneka MT, Feinstein DL. Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. J Neurosci Res. 2002 Feb 15; 67(4):461-70. PMID: 11835313.
      View in: PubMed
    141. Lu A, Ran RQ, Clark J, Reilly M, Nee A, Sharp F. 17-beta-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons. J Cereb Blood Flow Metab. 2002 Feb; 22(2):183-95. PMID: 11823716.
      View in: PubMed