Ian Howard Mchardy

Title(s)Assistant Professor, Medical Microbiology and Immunology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Heidari A, Quinlan M, Benjamin DJ, Laurence B, Mu A, Ngai T, Hoffman WJ, Cohen SH, McHardy I, Johnson R, Thompson GR. Isavuconazole in the Treatment of Coccidioidal Meningitis. Antimicrob Agents Chemother. 2019 Mar; 63(3). PMID: 30559134.
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    2. Thompson GR, Krois CR, Affolter VK, Everett AD, Varjonen EK, Sharon VR, Singapuri A, Dennis M, McHardy I, Yoo HS, Fedor DM, Wiederhold NP, Aaron PA, Gelli A, Napoli JL, White SD. Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. Antimicrob Agents Chemother. 2019 Feb; 63(2). PMID: 30455235.
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    3. McHardy IH, Dinh BN, Waldman S, Stewart E, Bays D, Pappagianis D, Thompson GR. Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. J Clin Microbiol. 2018 Dec; 56(12). PMID: 30257902.
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    4. Hoffmann WJ, McHardy I, Thompson GR. Itraconazole induced hypertension and hypokalemia: Mechanistic evaluation. Mycoses. 2018 May; 61(5):337-339. PMID: 29385285.
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    5. McHardy I, Romanelli A, Harris LJ, Opp G, Gaudino R, Torres A, Polage CR, Tuscano JM, Thompson GR. Infectious risks associated with medicinal Cannabis: Potential implications for immunocompromised patients? J Infect. 2018 May; 76(5):500-501. PMID: 29408325.
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    6. Stewart ER, Eldridge ML, McHardy I, Cohen SH, Thompson GR. Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis. Mycopathologia. 2018 Jun; 183(3):619-622. PMID: 29340909.
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    7. Thompson GR, Chang D, Wittenberg RR, McHardy I, Semrad A. In Vivo 11ß-Hydroxysteroid Dehydrogenase Inhibition in Posaconazole-Induced Hypertension and Hypokalemia. Antimicrob Agents Chemother. 2017 08; 61(8). PMID: 28533238.
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    8. McHardy IH, Veltman J, Hindler J, Bruxvoort K, Carvalho MM, Humphries RM. Clinical and Microbiological Aspects of ß-Lactam Resistance in Staphylococcus lugdunensis. J Clin Microbiol. 2017 02; 55(2):585-595. PMID: 27927926.
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    9. Jacobs JP, Goudarzi M, Singh N, Tong M, McHardy IH, Ruegger P, Asadourian M, Moon BH, Ayson A, Borneman J, McGovern DP, Fornace AJ, Braun J, Dubinsky M. A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients. Cell Mol Gastroenterol Hepatol. 2016 Nov; 2(6):750-766. PMID: 28174747.
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    10. Li X, LeBlanc J, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Barron G, McGovern D, McDonald K, Newberry R, Graeber T, Horvath S, Goodglick L, Braun J. Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2016 Sep; 2(5):567-583. PMID: 28174738.
      View in: PubMed
    11. Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Curr Protoc Immunol. 2014 Nov 03; 107:7.41.1-11. PMID: 25367129; PMCID: PMC4457454.
    12. Deak E, Charlton CL, Bobenchik AM, Miller SA, Pollett S, McHardy IH, Wu MT, Garner OB. Comparison of the Vitek MS and Bruker Microflex LT MALDI-TOF MS platforms for routine identification of commonly isolated bacteria and yeast in the clinical microbiology laboratory. Diagn Microbiol Infect Dis. 2015 Jan; 81(1):27-33. PMID: 25446889.
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    13. Tong M, McHardy I, Ruegger P, Goudarzi M, Kashyap PC, Haritunians T, Li X, Graeber TG, Schwager E, Huttenhower C, Fornace AJ, Sonnenburg JL, McGovern DP, Borneman J, Braun J. Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. ISME J. 2014 Nov; 8(11):2193-206. PMID: 24781901; PMCID: PMC4992076.
    14. Kaplan A, Kaplan CW, He X, McHardy I, Shi W, Lux R. Characterization of aid1, a novel gene involved in Fusobacterium nucleatum interspecies interactions. Microb Ecol. 2014 Aug; 68(2):379-87. PMID: 24643713; PMCID: PMC4104215.
    15. Sarkar J, McHardy IH, Simanian EJ, Shi W, Lux R. Transcriptional responses of Treponema denticola to other oral bacterial species. PLoS One. 2014; 9(2):e88361. PMID: 24505483; PMCID: PMC3914990.
    16. McHardy IH, Wu M, Shimizu-Cohen R, Couturier MR, Humphries RM. Detection of intestinal protozoa in the clinical laboratory. J Clin Microbiol. 2014 Mar; 52(3):712-20. PMID: 24197877; PMCID: PMC3957779.
    17. McHardy IH, Li X, Tong M, Ruegger P, Jacobs J, Borneman J, Anton P, Braun J. HIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota. Microbiome. 2013 Oct 12; 1(1):26. PMID: 24451087; PMCID: PMC3971626.
    18. McHardy IH, Goudarzi M, Tong M, Ruegger PM, Schwager E, Weger JR, Graeber TG, Sonnenburg JL, Horvath S, Huttenhower C, McGovern DP, Fornace AJ, Borneman J, Braun J. Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome. 2013 Jun 05; 1(1):17. PMID: 24450808; PMCID: PMC3971612.
    19. Hu W, Li L, Sharma S, Wang J, McHardy I, Lux R, Yang Z, He X, Gimzewski JK, Li Y, Shi W. DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides. PLoS One. 2012; 7(12):e51905. PMID: 23300576; PMCID: PMC3530553.
    20. Hu W, Wang J, McHardy I, Lux R, Yang Z, Li Y, Shi W. Effects of exopolysaccharide production on liquid vegetative growth, stress survival, and stationary phase recovery in Myxococcus xanthus. J Microbiol. 2012 Apr; 50(2):241-8. PMID: 22538652; PMCID: PMC3819231.
    21. McHardy I, Keegan C, Sim JH, Shi W, Lux R. Transcriptional profiles of Treponema denticola in response to environmental conditions. PLoS One. 2010 Oct 27; 5(10):e13655. PMID: 21048920; PMCID: PMC2965109.
    22. Jia Q, Freeman ML, Yager EJ, McHardy I, Tong L, Martinez-Guzman D, Rickabaugh T, Hwang S, Blackman MA, Sun R, Wu TT. Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency. J Virol. 2010 Mar; 84(5):2453-65. PMID: 20015983; PMCID: PMC2820913.
    23. Eckert R, Mchardy I, Yarbrough DK, He J, Qi F, Anderson MH, Shi W. Stability and activity in sputum of G10KHc, a potent anti-Pseudomonas antimicrobial peptide. Chem Biol Drug Des. 2007 Nov; 70(5):456-60. PMID: 17927719.
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    24. Eckert R, Brady KM, Greenberg EP, Qi F, Yarbrough DK, He J, McHardy I, Anderson MH, Shi W. Enhancement of antimicrobial activity against pseudomonas aeruginosa by coadministration of G10KHc and tobramycin. Antimicrob Agents Chemother. 2006 Nov; 50(11):3833-8. PMID: 16940063; PMCID: PMC1635211.
    25. Aguilar HC, Matreyek KA, Filone CM, Hashimi ST, Levroney EL, Negrete OA, Bertolotti-Ciarlet A, Choi DY, McHardy I, Fulcher JA, Su SV, Wolf MC, Kohatsu L, Baum LG, Lee B. N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry. J Virol. 2006 May; 80(10):4878-89. PMID: 16641279; PMCID: PMC1472062.
    26. Jia Q, Chernishof V, Bortz E, Mchardy I, Wu TT, Liao HI, Sun R. Murine gammaherpesvirus 68 open reading frame 45 plays an essential role during the immediate-early phase of viral replication. J Virol. 2005 Apr; 79(8):5129-41. PMID: 15795297; PMCID: PMC1069521.