Ignacio Saez

Title(s)Assistant Professor, Neurological Surgery
SchoolUniversity of California, Davis
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    Invasive decoding and stimulation of altered reward computations in depression
    NIH R01MH124763Sep 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Electrocorticography of human prefrontal cortex during value-based decision-making
    NIH K01MH108815Aug 1, 2016 - Jul 31, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A rapid theta network mechanism for flexible information encoding. Nat Commun. 2023 May 19; 14(1):2872. Johnson EL, Lin JJ, King-Stephens D, Weber PB, Laxer KD, Saez I, Girgis F, D'Esposito M, Knight RT, Badre D. PMID: 37208373; PMCID: PMC10198978.
      View in: PubMed   Mentions:
    2. Invasive Computational Psychiatry. Biol Psychiatry. 2023 04 15; 93(8):661-670. Saez I, Gu X. PMID: 36641365; PMCID: PMC10038930.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Subthalamic nucleus deep brain stimulation programming settings do not correlate with Parkinson's disease severity. Acta Neurochir (Wien). 2022 09; 164(9):2271-2278. Far R, Saez I, Sardo A, Ovruchesky E, Sperry L, Zhang L, Shahlaie K, Girgis F. PMID: 35751700.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Gender bias in academia: A lifetime problem that needs solutions. Neuron. 2021 07 07; 109(13):2047-2074. Llorens A, Tzovara A, Bellier L, Bhaya-Grossman I, Bidet-Caulet A, Chang WK, Cross ZR, Dominguez-Faus R, Flinker A, Fonken Y, Gorenstein MA, Holdgraf C, Hoy CW, Ivanova MV, Jimenez RT, Jun S, Kam JWY, Kidd C, Marcelle E, Marciano D, Martin S, Myers NE, Ojala K, Perry A, Pinheiro-Chagas P, Riès SK, Saez I, Skelin I, Slama K, Staveland B, Bassett DS, Buffalo EA, Fairhall AL, Kopell NJ, Kray LJ, Lin JJ, Nobre AC, Riley D, Solbakk AK, Wallis JD, Wang XJ, Yuval-Greenberg S, Kastner S, Knight RT, Dronkers NF. PMID: 34237278; PMCID: PMC8553227.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    5. The impact of sub specialization within functional neurosurgery on patient outcomes in a comprehensive epilepsy center. Clin Neurol Neurosurg. 2021 Apr 20; 205:106636. Clark AJ, Samuel R, Saez I, Kennedy J, Seyal M, Shahlaie K, Girgis F. PMID: 33984798.
      View in: PubMed   Mentions:    Fields:    
    6. Superior accuracy and precision of SEEG electrode insertion with frame-based vs. frameless stereotaxy methods. Acta Neurochir (Wien). 2020 10; 162(10):2527-2532. Girgis F, Ovruchesky E, Kennedy J, Seyal M, Shahlaie K, Saez I. PMID: 32458403.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Comparison of Intraoperative Computed Tomography Scan with Postoperative Magnetic Resonance Imaging for Determining Deep Brain Stimulation Electrode Coordinates. World Neurosurg. 2020 06; 138:e330-e335. Girgis F, Zarabi H, Said M, Zhang L, Shahlaie K, Saez I. PMID: 32112943.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Making the jump: Expert guidance on transitioning to academic independence. Eur J Neurosci. 2020 04; 51(7):1515-1525. Saez I, Berry AS, Elie JE, Santacruz SR. PMID: 31199533; PMCID: PMC8009293.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Mind Over Matter: Cognitive Neuroengineering. Cerebrum. 2019 May-Jun; 2019. Moxon K, Saez I, Ditterich J. PMID: 32206166; PMCID: PMC7075497.
      View in: PubMed   Mentions: 1  
    10. From adagio to allegretto: The changing tempo of theta frequencies in epilepsy and its relation to interneuron function. Neurobiol Dis. 2019 09; 129:169-181. Moxon KA, Shahlaie K, Girgis F, Saez I, Kennedy J, Gurkoff GG. PMID: 30798003.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    11. Encoding of Multiple Reward-Related Computations in Transient and Sustained High-Frequency Activity in Human OFC. Curr Biol. 2018 09 24; 28(18):2889-2899.e3. Saez I, Lin J, Stolk A, Chang E, Parvizi J, Schalk G, Knight RT, Hsu M. PMID: 30220499; PMCID: PMC6590063.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    12. Distinguishing neural correlates of context-dependent advantageous- and disadvantageous-inequity aversion. Proc Natl Acad Sci U S A. 2018 08 14; 115(33):E7680-E7689. Gao X, Yu H, Sáez I, Blue PR, Zhu L, Hsu M, Zhou X. PMID: 30061413; PMCID: PMC6099874.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    13. Integrated analysis of anatomical and electrophysiological human intracranial data. Nat Protoc. 2018 07; 13(7):1699-1723. Stolk A, Griffin S, van der Meij R, Dewar C, Saez I, Lin JJ, Piantoni G, Schoffelen JM, Knight RT, Oostenveld R. PMID: 29988107; PMCID: PMC6548463.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    14. The Protective Action Encoding of Serotonin Transients in the Human Brain. Neuropsychopharmacology. 2018 05; 43(6):1425-1435. Moran RJ, Kishida KT, Lohrenz T, Saez I, Laxton AW, Witcher MR, Tatter SB, Ellis TL, Phillips PE, Dayan P, Montague PR. PMID: 29297512; PMCID: PMC5916372.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    15. Asymmetry in functional connectivity of the human habenula revealed by high-resolution cardiac-gated resting state imaging. Hum Brain Mapp. 2016 07; 37(7):2602-15. Hétu S, Luo Y, Saez I, D'Ardenne K, Lohrenz T, Montague PR. PMID: 27038008; PMCID: PMC4905773.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    16. Role of GABAA-Mediated Inhibition and Functional Assortment of Synapses onto Individual Layer 4 Neurons in Regulating Plasticity Expression in Visual Cortex. PLoS One. 2016; 11(2):e0147642. Saez I, Friedlander MJ. PMID: 26841221; PMCID: PMC4739708.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    17. Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward. Proc Natl Acad Sci U S A. 2016 Jan 05; 113(1):200-5. Kishida KT, Saez I, Lohrenz T, Witcher MR, Laxton AW, Tatter SB, White JP, Ellis TL, Phillips PE, Montague PR. PMID: 26598677; PMCID: PMC4711839.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    18. Dopamine modulates egalitarian behavior in humans. Curr Biol. 2015 Mar 30; 25(7):912-9. Sáez I, Zhu L, Set E, Kayser A, Hsu M. PMID: 25802148; PMCID: PMC4627633.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    19. From genes to behavior: placing cognitive models in the context of biological pathways. Front Neurosci. 2014; 8:336. Saez I, Set E, Hsu M. PMID: 25414628; PMCID: PMC4220121.
      View in: PubMed   Mentions: 4  
    20. Dissociable contribution of prefrontal and striatal dopaminergic genes to learning in economic games. Proc Natl Acad Sci U S A. 2014 Jul 01; 111(26):9615-20. Set E, Saez I, Zhu L, Houser DE, Myung N, Zhong S, Ebstein RP, Chew SH, Hsu M. PMID: 24979760; PMCID: PMC4084431.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    21. Sub-second dopamine detection in human striatum. PLoS One. 2011; 6(8):e23291. Kishida KT, Sandberg SG, Lohrenz T, Comair YG, Sáez I, Phillips PE, Montague PR. PMID: 21829726; PMCID: PMC3150430.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    22. Plasticity between neuronal pairs in layer 4 of visual cortex varies with synapse state. J Neurosci. 2009 Dec 02; 29(48):15286-98. Sáez I, Friedlander MJ. PMID: 19955381; PMCID: PMC2824571.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    23. Synaptic output of individual layer 4 neurons in guinea pig visual cortex. J Neurosci. 2009 Apr 15; 29(15):4930-44. Sáez I, Friedlander MJ. PMID: 19369562; PMCID: PMC2680913.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    24. Modulation of inhibitory and excitatory synaptic transmission in rat inferior colliculus after unilateral cochleectomy: an in situ and immunofluorescence study. Neuroscience. 2006 Sep 01; 141(3):1193-207. Argence M, Saez I, Sassu R, Vassias I, Vidal PP, de Waele C. PMID: 16757119.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
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