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James Hildreth, MD; PhD

Title(s)Adjunct Professor, Medical Microbiology and Immunology
SchoolUniversity of California, Davis
Address451 Health Sciences Drive
CA 95616
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    1. Endogenous Retroviral Envelope Syncytin Induces HIV-1 Spreading and Establishes HIV Reservoirs in Placenta. Cell Rep. 2020 Mar 31; 30(13):4528-4539.e4. Tang Y, Woodward BO, Pastor L, George AM, Petrechko O, Nouvet FJ, Haas DW, Jiang G, Hildreth JEK. PMID: 32234485.
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    2. BK Virus Replication in the Glomerular Vascular Unit: Implications for BK Virus Associated Nephropathy. Viruses. 2019 06 27; 11(7). Popik W, Khatua AK, Fabre NF, Hildreth JEK, Alcendor DJ. PMID: 31252545.
      View in: PubMed   Mentions: 2     Fields:    
    3. Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation. mSphere. 2018 11 07; 3(6). Matassoli FL, Leão IC, Bezerra BB, Pollard RB, Lütjohann D, Hildreth JEK, Arruda LB. PMID: 30404938.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1. Cell Death Dis. 2018 10 03; 9(10):1019. Singhal A, Szente L, Hildreth JEK, Song B. PMID: 30282967.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV. Sci Rep. 2018 06 11; 8(1):8812. Dong XH, Ho MH, Liu B, Hildreth J, Dash C, Goodwin JS, Balasubramaniam M, Chen CH, Xie H. PMID: 29891956.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Phosphorodiamidate morpholino targeting the 5' untranslated region of the ZIKV RNA inhibits virus replication. Virology. 2018 06; 519:77-85. Popik W, Khatua A, Hildreth JEK, Lee B, Alcendor DJ. PMID: 29679791.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1-HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1. mSphere. 2018 04 25; 3(2). Tang Y, George AM, Petrechko O, Nouvet FJ, Sweet SD, Tanaka Y, Imbiakha BS, Jiang G, Gao W, Anastos K, Hildreth JEK. PMID: 29624497.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. HIV As Trojan Exosome: Immunological Paradox Explained? Front Immunol. 2017; 8:1715. Hildreth JEK. PMID: 29250079.
      View in: PubMed   Mentions: 2     Fields:    
    9. Hyaluronic Acid-Based Biocompatible Supramolecular Assembly for Sustained Release of Antiretroviral Drug. J Pharm Sci. 2016 09; 105(9):2760-2769. Song B, Puskás I, Szente L, Hildreth JEK. PMID: 26975245.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation. PLoS Pathog. 2015 Jul; 11(7):e1005066. Jiang G, Mendes EA, Kaiser P, Wong DP, Tang Y, Cai I, Fenton A, Melcher GP, Hildreth JE, Thompson GR, Wong JK, Dandekar S. PMID: 26225771.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    11. Heat-stable molecule derived from Streptococcus cristatus induces APOBEC3 expression and inhibits HIV-1 replication. PLoS One. 2014; 9(8):e106078. Wang Z, Luo Y, Shao Q, Kinlock BL, Wang C, Hildreth JE, Xie H, Liu B. PMID: 25165817.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. Infection of female primary lower genital tract epithelial cells after natural pseudotyping of HIV-1: possible implications for sexual transmission of HIV-1. PLoS One. 2014; 9(7):e101367. Tang Y, George A, Nouvet F, Sweet S, Emeagwali N, Taylor HE, Simmons G, Hildreth JE. PMID: 25010677.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Greater ethnic diversity correlates with lower HIV prevalence in Africa: justification for an alloimmunity vaccine. HIV AIDS (Auckl). 2013; 5:75-80. Zamani C, Elzey JD, Hildreth JE. PMID: 23610530.
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    14. The conserved set of host proteins incorporated into HIV-1 virions suggests a common egress pathway in multiple cell types. J Proteome Res. 2013 May 03; 12(5):2045-54. Linde ME, Colquhoun DR, Ubaida Mohien C, Kole T, Aquino V, Cotter R, Edwards N, Hildreth JE, Graham DR. PMID: 23432411.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    15. Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies. J Mol Biol. 2013 Jun 12; 425(11):2027-2038. Armstrong A, Hildreth JEK, Amzel LM. PMID: 23473830.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA. Virol J. 2012 Nov 19; 9:277. Emeagwali N, Hildreth JE. PMID: 23164059.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Cholesterol depletion inactivates XMRV and leads to viral envelope protein release from virions: evidence for role of cholesterol in XMRV infection. PLoS One. 2012; 7(10):e48013. Tang Y, George A, Taylor T, Hildreth JE. PMID: 23110160.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. Antibody against integrin lymphocyte function-associated antigen 1 inhibits HIV type 1 infection in primary cells through caspase-8-mediated apoptosis. AIDS Res Hum Retroviruses. 2013 Feb; 29(2):371-83. Walker TN, Cimakasky LM, Coleman EM, Madison MN, Hildreth JE. PMID: 22697794.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Caveolin-1 suppresses human immunodeficiency virus-1 replication by inhibiting acetylation of NF-?B. Virology. 2012 Oct 10; 432(1):110-9. Simmons GE, Taylor HE, Hildreth JE. PMID: 22748181.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    20. Cultural differences in acceptability of a vaginal microbicide: a comparison between potential users from Nashville, Tennessee, USA, and Kafue and Mumbwa, Zambia. HIV AIDS (Auckl). 2012; 4:73-80. Rice VM, Maimbolwa MC, Nkandu EM, Hampton JF, Lee JE, Hildreth JE. PMID: 22629115.
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    21. Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomes. Virol J. 2012 Jan 24; 9:31. Coleman EM, Walker TN, Hildreth JE. PMID: 22273177.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    22. Filamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly. J Biol Chem. 2011 Aug 12; 286(32):28498-510. Cooper J, Liu L, Woodruff EA, Taylor HE, Goodwin JS, D'Aquila RT, Spearman P, Hildreth JE, Dong X. PMID: 21705339.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    23. Sterol regulatory element-binding protein 2 couples HIV-1 transcription to cholesterol homeostasis and T cell activation. J Virol. 2011 Aug; 85(15):7699-709. Taylor HE, Linde ME, Khatua AK, Popik W, Hildreth JE. PMID: 21613400.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    24. N-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination. J Virol. 2011 May; 85(9):4510-9. Wang Y, Shao Q, Yu X, Kong W, Hildreth JE, Liu B. PMID: 21345952.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    25. Non-productive HIV-1 infection of human glomerular and urinary podocytes. Virology. 2010 Dec 05; 408(1):119-27. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 20937511.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    26. Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F. Virology. 2010 Apr 25; 400(1):68-75. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 20153011.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    27. Polyubiquitination of APOBEC3G is essential for its degradation by HIV-1 Vif. J Virol. 2010 May; 84(9):4840-4. Shao Q, Wang Y, Hildreth JE, Liu B. PMID: 20147392.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    28. Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments. J Virol. 2009 Aug; 83(16):7982-95. Tang Y, Leao IC, Coleman EM, Broughton RS, Hildreth JE. PMID: 19474101.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    29. Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells. J Virol. 2009 Jan; 83(2):512-21. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 18987139.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    30. Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges. J Virol. 2008 Jul; 82(13):6591-9. Ambrose Z, Compton L, Piatak M, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN. PMID: 18434406.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    31. Delipidated retroviruses as potential autologous therapeutic vaccines--a pilot experiment. Exp Biol Med (Maywood). 2008 Jun; 233(6):732-40. Kitabwalla M, Ansari AA, Villinger F, Akeefe H, Conner AP, Mayne AE, Hildreth JE. PMID: 18408147.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    32. Cervicovaginal evaluation in macaques used as a model for topical microbicide safety studies. J Med Primatol. 2008 Feb; 37 Suppl 1:65-73. Scorpio DG, Ruben DS, Liao Z, Hildreth JE, Fletcher CA. PMID: 18269532.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    33. Production and characterization of a monoclonal antibody against Niemann Pick type C protein. Hybridoma (Larchmt). 2006 Aug; 25(4):216-24. Leao IC, Maciel M, Hildreth JE. PMID: 16934018.
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    34. Lactobacilli-expressed single-chain variable fragment (scFv) specific for intercellular adhesion molecule 1 (ICAM-1) blocks cell-associated HIV-1 transmission across a cervical epithelial monolayer. J Immunol. 2006 May 01; 176(9):5627-36. Chancey CJ, Khanna KV, Seegers JF, Zhang GW, Hildreth J, Langan A, Markham RB. PMID: 16622032.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    35. Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J Cell Biol. 2006 Mar 13; 172(6):923-35. Booth AM, Fang Y, Fallon JK, Yang JM, Hildreth JE, Gould SJ. PMID: 16533950.
      View in: PubMed   Mentions: 203     Fields:    Translation:HumansCells
    36. Characterization of an anti-lymphocyte function-associated antigen-1 antibody in a simian immunodeficiency virus-pig-tailed macaque (Macaca nemestrina) model. Comp Med. 2006 Feb; 56(1):23-30. Fletcher CA, Liao Z, Adams RJ, Carter DL, Jones OD, Davis HG, Bryant JL, Hildreth JE. PMID: 16521856.
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    37. Enhancement of cell mediated immune responses using lipid depleted lentivirus as immunogen: a novel approach for inducing recognition of new viral epitopes. Vaccine. 2005 Sep 07; 23(38):4666-77. Kitabwalla M, Villinger F, Akeefe H, Liao Z, Mayne AE, Gargano L, Conner AP, Maltais JA, Kunas G, Hildreth JE, Ansari AA, Bellotti M. PMID: 15955600.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    38. The evolution of alloimmunity and the genesis of adaptive immunity. Q Rev Biol. 2004 Dec; 79(4):359-82. Gould SJ, Hildreth JE, Booth AM. PMID: 15669770.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    39. Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions. J Virol. 2003 Dec; 77(24):13084-92. Mansharamani M, Graham DR, Monie D, Lee KK, Hildreth JE, Siliciano RF, Wilson KL. PMID: 14645565.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    40. Evidence that HIV budding in primary macrophages occurs through the exosome release pathway. J Biol Chem. 2003 Dec 26; 278(52):52347-54. Nguyen DG, Booth A, Gould SJ, Hildreth JE. PMID: 14561735.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    41. The Trojan exosome hypothesis. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10592-7. Gould SJ, Booth AM, Hildreth JE. PMID: 12947040.
      View in: PubMed   Mentions: 167     Fields:    Translation:Cells
    42. Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells. AIDS Res Hum Retroviruses. 2003 Aug; 19(8):675-87. Liao Z, Graham DR, Hildreth JE. PMID: 13678470.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    43. Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts. J Virol. 2003 Aug; 77(15):8237-48. Graham DR, Chertova E, Hilburn JM, Arthur LO, Hildreth JE. PMID: 12857892.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    44. Differential expression of human immunodeficiency virus coreceptors, by CEM, CEMVBL, and CEM E1000 cells. J Infect Dis. 2003 Mar 01; 187(5):874-5; author reply 875-6. Owen A, Chandler B, Ford J, Khoo S, Back D. PMID: 12599066.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages. Eur J Immunol. 2003 Feb; 33(2):483-93. Nguyen DG, Hildreth JE. PMID: 12645947.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    46. Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS. AIDS Res Hum Retroviruses. 2002 Nov 01; 18(16):1197-205. Banks ND, Kinsey N, Clements J, Hildreth JE. PMID: 12487826.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    47. Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection. J Infect Dis. 2002 Aug 01; 186(3):332-40. Speck RR, Yu XF, Hildreth J, Flexner C. PMID: 12134229.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    48. Oligomers of glycamino acid. Bioorg Med Chem. 2002 Jun; 10(6):1999-2013. Suhara Y, Yamaguchi Y, Collins B, Schnaar RL, Yanagishita M, Hildreth JE, Shimada I, Ichikawa Y. PMID: 11937360.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    49. Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent. J Clin Invest. 2002 Jan; 109(2):205-11. Khanna KV, Whaley KJ, Zeitlin L, Moench TR, Mehrazar K, Cone RA, Liao Z, Hildreth JE, Hoen TE, Shultz L, Markham RB. PMID: 11805132.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    50. Characterization of new syncytium-inhibiting monoclonal antibodies implicates lipid rafts in human T-cell leukemia virus type 1 syncytium formation. J Virol. 2001 Aug; 75(16):7351-61. Niyogi K, Hildreth JE. PMID: 11462007.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    51. Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1. AIDS Res Hum Retroviruses. 2001 Jul 20; 17(11):1009-19. Liao Z, Cimakasky LM, Hampton R, Nguyen DH, Hildreth JE. PMID: 11485618.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    52. LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication. Virology. 2000 Aug 01; 273(2):307-15. Roos JW, Maughan MF, Liao Z, Hildreth JE, Clements JE. PMID: 10915601.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    53. CD4-independent, CCR5-dependent simian immunodeficiency virus infection and chemotaxis of human cells. J Virol. 2000 Aug; 74(15):6720-4. Iyengar S, Schwartz DH, Clements JE, Hildreth JE. PMID: 10888609.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    54. High-affinity anti-ganglioside IgG antibodies raised in complex ganglioside knockout mice: reexamination of GD1a immunolocalization. J Neurochem. 2000 Jul; 75(1):404-12. Lunn MP, Johnson LA, Fromholt SE, Itonori S, Huang J, Vyas AA, Hildreth JE, Griffin JW, Schnaar RL, Sheikh KA. PMID: 10854286.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    55. Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J Virol. 2000 Apr; 74(7):3264-72. Nguyen DH, Hildreth JE. PMID: 10708443.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansCells
    56. Increased infectivity of HIV type 1 particles bound to cell surface and solid-phase ICAM-1 and VCAM-1 through acquired adhesion molecules LFA-1 and VLA-4. AIDS Res Hum Retroviruses. 2000 Mar 01; 16(4):355-66. Liao Z, Roos JW, Hildreth JE. PMID: 10716373.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    57. Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha. J Immunol. 2000 Feb 01; 164(3):1408-15. Khanna KV, Yu XF, Ford DH, Ratner L, Hildreth JK, Markham RB. PMID: 10640756.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    58. Production and characterization of monoclonal antibodies against pigtailed macaque (Macaca nemestrina) cell adhesion molecules. Hybridoma. 1999 Oct; 18(5):437-47. Hildreth JE, Mankowski JL, Zink C, Clements JE. PMID: 10600031.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    59. CD56 identifies monocytes and not natural killer cells in rhesus macaques. Cytometry. 1999 Sep 01; 37(1):41-50. Carter DL, Shieh TM, Blosser RL, Chadwick KR, Margolick JB, Hildreth JE, Clements JE, Zink MC. PMID: 10451505.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    60. The channel-forming toxin aerolysin neutralizes human immunodeficiency virus type 1. Mol Microbiol. 1999 Aug; 33(3):659-66. Nguyen DH, Liao Z, Buckley JT, Hildreth JE. PMID: 10417655.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    61. T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: implications for HIV pathogenesis. J Immunol. 1999 May 15; 162(10):6263-7. Iyengar S, Schwartz DH, Hildreth JE. PMID: 10229873.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    62. Enhanced HIV type 1 neutralization by human anti-glycoprotein 120 monoclonal antibodies in the presence of monoclonal antibodies to lymphocyte function-associated molecule 1. AIDS Res Hum Retroviruses. 1999 Apr 10; 15(6):523-31. Hioe CE, Hildreth JE, Zolla-Pazner S. PMID: 10221529.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    63. Antibody-dependent cell-mediated cytotoxicity can protect PBMC from infection by cell-associated HIV-1. Clin Immunol. 1999 Feb; 90(2):203-12. Hildreth JE, Hampton R, Halsey NA. PMID: 10080832.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    64. Syncytium-inhibiting monoclonal antibodies produced against human T-cell lymphotropic virus type 1-infected cells recognize class II major histocompatibility complex molecules and block by protein crowding. J Virol. 1998 Dec; 72(12):9544-52. Hildreth JE. PMID: 9811687.
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    65. Role of cellular adhesion molecules in HIV type 1 infection and their impact on virus neutralization. AIDS Res Hum Retroviruses. 1998 Oct; 14 Suppl 3:S247-54. Hioe CE, Bastiani L, Hildreth JE, Zolla-Pazner S. PMID: 9814951.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    66. Immunoaffinity localization of the enzyme xanthine oxidase on the outside surface of the endothelial cell plasma membrane. Surgery. 1998 Sep; 124(3):551-60. Vickers S, Schiller HJ, Hildreth JE, Bulkley GB. PMID: 9736909.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    67. Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells. J Virol. 1998 Jun; 72(6):5251-5. Iyengar S, Hildreth JE, Schwartz DH. PMID: 9573299.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    68. Human T-cell lymphotropic virus type 1 (HTLV-1)-induced syncytium formation mediated by vascular cell adhesion molecule-1: evidence for involvement of cell adhesion molecules in HTLV-1 biology. J Virol. 1997 Feb; 71(2):1173-80. Hildreth JE, Subramanium A, Hampton RA. PMID: 8995639.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    69. Mutations in the matrix protein of human immunodeficiency virus type 1 inhibit surface expression and virion incorporation of viral envelope glycoproteins in CD4+ T lymphocytes. J Virol. 1997 Feb; 71(2):1443-52. Lee YM, Tang XB, Cimakasky LM, Hildreth JE, Yu XF. PMID: 8995670.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    70. Antibody to human MHC class I inhibits SIVsmmPBj1.9-induced proliferation of pigtailed macaque lymphocytes. Exp Clin Immunogenet. 1997; 14(2):141-8. Baskar PV, Nagel JE, Narayan O, McClure HM, Adler WH, Hildreth JE. PMID: 9395890.
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    71. Anti-HLA class I antibody inhibits Staphylococcus enterotoxin A (SEA)-induced proliferation of human PBMC. Cell Immunol. 1996 Aug 25; 172(1):135-8. Baskar P, Hildreth JE, Chrest FJ, Nagel JE, Adler WH. PMID: 8806816.
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    72. Synthesis of sulfated ß-1,6-linked oligosaccharide mimetics: A novel potent inhibitor of HIV replication. Tetrahedron Letters. 1996 Apr 1; 37(15):2549-2552. Yoshitomo Suhara, Mie Ichikawa, James E.K. Hildreth, Yoshitaka Ichikawa. .
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    73. Synthesis of a new carbohydrate mimetics: “carbopeptoid” containing a C-1 carboxylate and C-2 amino group. Tetrahedron Letters. 1996 Mar 1; 37(10):1575-1578. Yoshitomo Suhara, James E.K. Hildreth, Yoshitaka Ichikawa. .
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    74. Assessment of cell binding to hyaluronic acid in a solid-phase assay. Anal Biochem. 1996 Jan 15; 233(2):216-20. Guo MM, Hildreth JE. PMID: 8789721.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    75. Factors modifying protective effect of anti-CD18 antibodies on myocardial reperfusion injury in dogs. Am J Physiol. 1996 Jan; 270(1 Pt 2):H53-64. Perez RG, Arai M, Richardson C, DiPaula A, Siu C, Matsumoto N, Hildreth JE, Mariscalco MM, Smith CW, Becker LC. PMID: 8769734.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    76. HIV acquires functional adhesion receptors from host cells. AIDS Res Hum Retroviruses. 1995 Sep; 11(9):1007-13. Guo MM, Hildreth JE. PMID: 8554897.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    77. Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1. J Virol. 1995 Aug; 69(8):4628-32. Gomez MB, Hildreth JE. PMID: 7541842.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    78. Targeted delivery of immunomicrospheres in vivo. Drug Delivery. 1995 Jan 1; 2(3-4):166-174. Vu L. Truong, Jerry R. Williams, James E. K. Hildreth, Kam W. Leong. .
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    79. Presence in India of HIV type 1 similar to North American strains. AIDS Res Hum Retroviruses. 1994 Aug; 10(8):1039-41. Baskar PV, Ray SC, Rao R, Quinn TC, Hildreth JE, Bollinger RC. PMID: 7811535.
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    80. Simian immunodeficiency virus SIVsmmPBj 1.9 induces multinucleated giant cell formation in human peripheral blood monocytes. AIDS Res Hum Retroviruses. 1994 Jan; 10(1):73-80. Baskar P, Narayan O, McClure HM, Hildreth JE. PMID: 8179965.
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    81. Human gallstones contain pronucleating nonmucin glycoproteins that are immunoglobulins. Ann Surg. 1994 Jan; 219(1):25-33. Lipsett PA, Hildreth J, Kaufman HS, Lillemoe KD, Pitt HA. PMID: 8297172.
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    82. Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV. AIDS Res Hum Retroviruses. 1993 Nov; 9(11):1157-65. Orentas RJ, Hildreth JE. PMID: 8312057.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    83. HIV-induced loss of CD44 expression in monocytic cell lines. J Immunol. 1993 Aug 15; 151(4):2225-36. Guo MM, Hildreth JE. PMID: 8345206.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    84. Safety and immunogenicity of a recombinant protein influenza A vaccine in adult human volunteers and protective efficacy against wild-type H1N1 virus challenge. J Infect Dis. 1993 Mar; 167(3):593-601. Fries LF, Dillon SB, Hildreth JE, Karron RA, Funkhouser AW, Friedman CJ, Jones CS, Culleton VG, Clements ML. PMID: 8440931.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    85. A monoclonal antibody against a novel 20-kDa protein induces cell adhesion and cytoskeleton-dependent morphologic changes. J Immunol. 1992 Oct 15; 149(8):2549-59. Lin SL, Derr D, Hildreth JE. PMID: 1383318.
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    86. Anti-class II MHC antibody induces multinucleated giant cell formation from peripheral blood monocytes. J Leukoc Biol. 1992 Mar; 51(3):199-209. Orentas RJ, Reinlib L, Hildreth JE. PMID: 1541903.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    87. 3-Deaza-adenosine and inhibition of HIV. Lancet. 1992 Feb 15; 339(8790):438. Flexner CW, Hildreth JE, Kuncl RW, Drachman DB. PMID: 1346708.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    88. CD63/Pltgp40: a platelet activation antigen identical to the stage-specific, melanoma-associated antigen ME491. Blood. 1991 Jul 15; 78(2):280-4. Azorsa DO, Hyman JA, Hildreth JE. PMID: 2070066.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    89. Characterization of a novel self-associating Mr 40,000 platelet glycoprotein. Blood. 1991 Jan 01; 77(1):121-32. Hildreth JE, Derr D, Azorsa DO. PMID: 1984792.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    90. IL-3 augments adhesiveness for endothelium and CD11b expression in human basophils but not neutrophils. J Immunol. 1990 Sep 15; 145(6):1832-7. Bochner BS, McKelvey AA, Sterbinsky SA, Hildreth JE, Derse CP, Klunk DA, Lichtenstein LM, Schleimer RP. PMID: 1697310.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    91. Induction of CD4+ human cytolytic T cells specific for HIV-infected cells by a gp160 subunit vaccine. Science. 1990 Jun 08; 248(4960):1234-7. Orentas RJ, Hildreth JE, Obah E, Polydefkis M, Smith GE, Clements ML, Siliciano RF. PMID: 2190315.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCellsPHPublic Health
    92. Homotypic cell aggregation induced by anti-CD44(Pgp-1) monoclonal antibodies and related to CD44(Pgp-1) expression. J Immunol. 1990 Mar 01; 144(5):1661-70. Belitsos PC, Hildreth JE, August JT. PMID: 1689752.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    93. Involvement of lymphocyte function-associated antigen-1 (LFA-1) but not ICAM-1 in a radioactive leukocyte cell-mediated immunity (LA-CMI) assay. J Clin Lab Immunol. 1990 Mar; 31(3):145-9. Fekete B, Hildreth JE, Holland JF, Bekesi JG. PMID: 1983768.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    94. Flow cytometric methods for the analysis of human basophil surface antigens and viability. J Immunol Methods. 1989 Dec 20; 125(1-2):265-71. Bochner BS, McKelvey AA, Schleimer RP, Hildreth JE, MacGlashan DW. PMID: 2607157.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    95. Production and characterization of monoclonal anti-CD18 anti-idiotype antibodies. Mol Immunol. 1989 Dec; 26(12):1155-67. Hildreth JE, Hyman JA. PMID: 2698997.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    96. Monoclonal antibodies against porcine LFA-1: species cross-reactivity and functional effects of beta-subunit-specific antibodies. Mol Immunol. 1989 Sep; 26(9):883-95. Hildreth JE, Holt V, August JT, Pescovitz MD. PMID: 2481234.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    97. Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation. Science. 1989 Jun 02; 244(4908):1075-8. Hildreth JE, Orentas RJ. PMID: 2543075.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    98. Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 1989 Jan; 268(1):360-78. Mane SM, Marzella L, Bainton DF, Holt VK, Cha Y, Hildreth JE, August JT. PMID: 2912382.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    99. The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor. EMBO J. 1987 Apr; 6(4):915-9. Law SK, Gagnon J, Hildreth JE, Wells CE, Willis AC, Wong AJ. PMID: 2954816.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    100. Effects of monoclonal antibodies to the alpha and beta chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions. Eur J Immunol. 1985 Sep; 15(9):888-92. Dongworth DW, Gotch FM, Hildreth JE, Morris A, McMichael AJ. PMID: 3930261.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    101. A high-performance liquid chromatographic procedure for the purification of mouse monoclonal antibodies. Anal Biochem. 1985 Jun; 147(2):451-4. Deschamps JR, Hildreth JE, Derr D, August JT. PMID: 4014689.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    102. The human lymphocyte function-associated (HLFA) antigen and a related macrophage differentiation antigen (HMac-1): functional effects of subunit-specific monoclonal antibodies. J Immunol. 1985 May; 134(5):3272-80. Hildreth JE, August JT. PMID: 2580022.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    103. An HLA class I specific monoclonal antibody that fails to bind to all HLA-A antigens. Hum Immunol. 1985 May; 13(1):13-9. Ellis SA, Taylor C, Hildreth JE, McMichael AJ. PMID: 2580818.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    104. Plasma membranes from influenza virus-infected cells induce in vitro human secondary virus-specific cytotoxic T lymphocyte responses. Mol Biol Med. 1983 Sep; 1(2):225-33. Hildreth JE, Gotch FM, McMichael AJ. PMID: 6334215.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    105. A human lymphocyte-associated antigen involved in cell-mediated lympholysis. Eur J Immunol. 1983 Mar; 13(3):202-8. Hildreth JE, Gotch FM, Hildreth PD, McMichael AJ. PMID: 6339253.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    106. Identification of a human Ia antigen that is different from HLA-DR and DC antigens. Immunogenetics. 1983; 17(6):623-35. Makgoba MW, Hildreth JE, McMichael AJ. PMID: 6407986.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    107. Lysis of allogeneic human lymphocytes by nonspecifically activated T-like cells. Eur J Immunol. 1982 Dec; 12(12):1002-5. McMichael AJ, Gotch FM, Hildreth JE. PMID: 6984389.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    108. N-D-Gluco-N-methylalkanamide compounds, a new class of non-ionic detergents for membrane biochemistry. Biochem J. 1982 Nov 01; 207(2):363-6. Hildreth JE. PMID: 7159387.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    109. Monoclonal antibodies to Epstein-Barr virus-induced, transformation-associated cell surface antigens: binding patterns and effect upon virus-specific T-cell cytotoxicity. Int J Cancer. 1982 Apr 15; 29(4):373-81. Rowe M, Hildreth JE, Rickinson AB, Epstein MA. PMID: 6282762.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
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