James Hildreth

Title(s)Adjunct Professor, Medical Microbiology and Immunology
SchoolUniversity of California, Davis
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of Natural Pseudotyping with Other Viruses in HIV Transmission
    NIH DP1AI106275Sep 30, 2011 - Jul 31, 2018
    Role: Principal Investigator
    Role of Natural Pseudotyping with Other Viruses in HIV Transmission
    NIH DP1OD008243Sep 30, 2011 - Jul 31, 2012
    Role: Principal Investigator
    Capacity Building Assistance (CBA) to Improve the Delivery and Effectiveness
    NIH U65PS001720Sep 30, 2009 - Mar 31, 2014
    Role: Co-Principal Investigator
    Meharry Clinical and Translational Research Center (MeTRC)
    NIH U54RR026140Sep 25, 2009 - Jun 30, 2014
    Role: Co-Principal Investigator
    HIV as Viral Exosome: Role of Rab GTPases and NPC1
    NIH R21AI062408Sep 15, 2004 - Aug 31, 2006
    Role: Principal Investigator
    Meharry Center for Health Disparities Research in HIV
    NIH U54RR019192Sep 30, 2003 - Sep 30, 2009
    Role: Principal Investigator
    Endowment for Health Disparities Research
    NIH S21MD000104Sep 30, 2001 - Jul 31, 2017
    Role: Principal Investigator
    Cyclodextrin as a Novel HIV Microbicide
    NIH R01HD040772Apr 27, 2001 - Jun 30, 2011
    Role: Principal Investigator
    NOVEL ANTI-HIV MICROBICIDES
    NIH R03HD039613Aug 1, 2000 - Jul 31, 2002
    Role: Principal Investigator
    12 DETECTORS 96 WELL MICROPLATE SCINT--LUMINES COUNTER
    NIH S10RR013029Sep 15, 1998 - Sep 14, 1999
    Role: Principal Investigator
    The RCMI Program in Health Disparities Research at Meharry Medical College
    NIH U54MD007586Sep 30, 1997 - Sep 20, 2022
    Role: Co-Principal Investigator
    Meharry RCMI Program in Women's Health Research
    NIH G12MD007586Sep 30, 1997 - Sep 20, 2017
    Role: Principal Investigator
    ROLE OF ADHESION MOLECULES IN THE PATHOBIOLOGY OF HIV
    NIH R01AI031806Sep 1, 1991 - Jan 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The COVID-19 Vaccine and Pregnant Minority Women in the US: Implications for Improving Vaccine Confidence and Uptake. Vaccines (Basel). 2022 Dec 12; 10(12). Alcendor DJ, Matthews-Juarez P, Smoot D, Hildreth JEK, Tabatabai M, Wilus D, Brown KY, Juarez PD. PMID: 36560532.
      View in: PubMed   Mentions:
    2. Hydroxypropyl-beta-cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines. Antiviral Res. 2022 09; 205:105373. Bezerra BB, Silva GPDD, Coelho SVA, Correa IA, Souza MRM, Macedo KVG, Matos BM, Tanuri A, Matassoli FL, Costa LJD, Hildreth JEK, Arruda LB. PMID: 35798224; PMCID: PMC9250893.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Breakthrough COVID-19 Infections in the US: Implications for Prolonging the Pandemic. Vaccines (Basel). 2022 May 11; 10(5). Alcendor DJ, Matthews-Juarez P, Smoot D, Hildreth JEK, Lamar K, Tabatabai M, Wilus D, Juarez PD. PMID: 35632512; PMCID: PMC9146933.
      View in: PubMed   Mentions: 4  
    4. Medroxyprogesterone Acetate (MPA) Enhances HIV-1 Accumulation and Release in Primary Cervical Epithelial Cells by Inhibiting Lysosomal Activity. Pathogens. 2021 Sep 14; 10(9). Jia X, Shao Q, Chaudhry AR, Kinlock BL, Izban MG, Zhang HY, Villalta F, Hildreth JEK, Liu B. PMID: 34578224; PMCID: PMC8465616.
      View in: PubMed   Mentions: 1  
    5. Vivo-Morpholino-Based Antiviral for SARS-CoV-2: Implications for Novel Therapies in the Treatment of Acute COVID-19 Disease. Biomedicines. 2021 Aug 15; 9(8). Hildreth JEK, Moulton JD, Alcendor DJ. PMID: 34440222; PMCID: PMC8394971.
      View in: PubMed   Mentions:
    6. Targeting COVID-19 Vaccine Hesitancy in Minority Populations in the US: Implications for Herd Immunity. Vaccines (Basel). 2021 May 11; 9(5). Hildreth JEK, Alcendor DJ. PMID: 34064726; PMCID: PMC8151325.
      View in: PubMed   Mentions: 45  
    7. Endogenous Retroviral Envelope Syncytin Induces HIV-1 Spreading and Establishes HIV Reservoirs in Placenta. Cell Rep. 2020 03 31; 30(13):4528-4539.e4. Tang Y, Woodward BO, Pastor L, George AM, Petrechko O, Nouvet FJ, Haas DW, Jiang G, Hildreth JEK. PMID: 32234485; PMCID: PMC7770760.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    8. BK Virus Replication in the Glomerular Vascular Unit: Implications for BK Virus Associated Nephropathy. Viruses. 2019 06 27; 11(7). Popik W, Khatua AK, Fabre NF, Hildreth JEK, Alcendor DJ. PMID: 31252545; PMCID: PMC6669441.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    9. Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation. mSphere. 2018 11 07; 3(6). Matassoli FL, Leão IC, Bezerra BB, Pollard RB, Lütjohann D, Hildreth JEK, Arruda LB. PMID: 30404938; PMCID: PMC6222057.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1. Cell Death Dis. 2018 10 03; 9(10):1019. Singhal A, Szente L, Hildreth JEK, Song B. PMID: 30282967; PMCID: PMC6170477.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    11. Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV. Sci Rep. 2018 06 11; 8(1):8812. Dong XH, Ho MH, Liu B, Hildreth J, Dash C, Goodwin JS, Balasubramaniam M, Chen CH, Xie H. PMID: 29891956; PMCID: PMC5995904.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsPHPublic Health
    12. Phosphorodiamidate morpholino targeting the 5' untranslated region of the ZIKV RNA inhibits virus replication. Virology. 2018 06; 519:77-85. Popik W, Khatua A, Hildreth JEK, Lee B, Alcendor DJ. PMID: 29679791; PMCID: PMC6503319.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1-HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1. mSphere. 2018 04 25; 3(2). Tang Y, George AM, Petrechko O, Nouvet FJ, Sweet SD, Tanaka Y, Imbiakha BS, Jiang G, Gao W, Anastos K, Hildreth JEK. PMID: 29624497; PMCID: PMC5885023.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    14. HIV As Trojan Exosome: Immunological Paradox Explained? Front Immunol. 2017; 8:1715. Hildreth JEK. PMID: 29250079; PMCID: PMC5716971.
      View in: PubMed   Mentions: 10     Fields:    
    15. Hyaluronic Acid-Based Biocompatible Supramolecular Assembly for Sustained Release of Antiretroviral Drug. J Pharm Sci. 2016 09; 105(9):2760-2769. Song B, Puskás I, Szente L, Hildreth JEK. PMID: 26975245.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation. PLoS Pathog. 2015 Jul; 11(7):e1005066. Jiang G, Mendes EA, Kaiser P, Wong DP, Tang Y, Cai I, Fenton A, Melcher GP, Hildreth JE, Thompson GR, Wong JK, Dandekar S. PMID: 26225771; PMCID: PMC4520526.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    17. Heat-stable molecule derived from Streptococcus cristatus induces APOBEC3 expression and inhibits HIV-1 replication. PLoS One. 2014; 9(8):e106078. Wang Z, Luo Y, Shao Q, Kinlock BL, Wang C, Hildreth JE, Xie H, Liu B. PMID: 25165817; PMCID: PMC4148350.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Infection of female primary lower genital tract epithelial cells after natural pseudotyping of HIV-1: possible implications for sexual transmission of HIV-1. PLoS One. 2014; 9(7):e101367. Tang Y, George A, Nouvet F, Sweet S, Emeagwali N, Taylor HE, Simmons G, Hildreth JE. PMID: 25010677; PMCID: PMC4092063.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    19. Greater ethnic diversity correlates with lower HIV prevalence in Africa: justification for an alloimmunity vaccine. HIV AIDS (Auckl). 2013; 5:75-80. Zamani C, Elzey JD, Hildreth JE. PMID: 23610530; PMCID: PMC3628525.
      View in: PubMed   Mentions: 2  
    20. The conserved set of host proteins incorporated into HIV-1 virions suggests a common egress pathway in multiple cell types. J Proteome Res. 2013 May 03; 12(5):2045-54. Linde ME, Colquhoun DR, Ubaida Mohien C, Kole T, Aquino V, Cotter R, Edwards N, Hildreth JE, Graham DR. PMID: 23432411; PMCID: PMC4065613.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    21. Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies. J Mol Biol. 2013 Jun 12; 425(11):2027-2038. Armstrong A, Hildreth JEK, Amzel LM. PMID: 23473830; PMCID: PMC3985606.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    22. Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA. Virol J. 2012 Nov 19; 9:277. Emeagwali N, Hildreth JE. PMID: 23164059; PMCID: PMC3547713.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Cholesterol depletion inactivates XMRV and leads to viral envelope protein release from virions: evidence for role of cholesterol in XMRV infection. PLoS One. 2012; 7(10):e48013. Tang Y, George A, Taylor T, Hildreth JE. PMID: 23110160; PMCID: PMC3482229.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. Antibody against integrin lymphocyte function-associated antigen 1 inhibits HIV type 1 infection in primary cells through caspase-8-mediated apoptosis. AIDS Res Hum Retroviruses. 2013 Feb; 29(2):371-83. Walker TN, Cimakasky LM, Coleman EM, Madison MN, Hildreth JE. PMID: 22697794; PMCID: PMC3552179.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Caveolin-1 suppresses human immunodeficiency virus-1 replication by inhibiting acetylation of NF-κB. Virology. 2012 Oct 10; 432(1):110-9. Simmons GE, Taylor HE, Hildreth JE. PMID: 22748181; PMCID: PMC3767293.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    26. Cultural differences in acceptability of a vaginal microbicide: a comparison between potential users from Nashville, Tennessee, USA, and Kafue and Mumbwa, Zambia. HIV AIDS (Auckl). 2012; 4:73-80. Rice VM, Maimbolwa MC, Nkandu EM, Hampton JF, Lee JE, Hildreth JE. PMID: 22629115; PMCID: PMC3358808.
      View in: PubMed   Mentions: 2  
    27. Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomes. Virol J. 2012 Jan 24; 9:31. Coleman EM, Walker TN, Hildreth JE. PMID: 22273177; PMCID: PMC3299633.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    28. Filamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly. J Biol Chem. 2011 Aug 12; 286(32):28498-510. Cooper J, Liu L, Woodruff EA, Taylor HE, Goodwin JS, D'Aquila RT, Spearman P, Hildreth JE, Dong X. PMID: 21705339; PMCID: PMC3151092.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    29. Sterol regulatory element-binding protein 2 couples HIV-1 transcription to cholesterol homeostasis and T cell activation. J Virol. 2011 Aug; 85(15):7699-709. Taylor HE, Linde ME, Khatua AK, Popik W, Hildreth JE. PMID: 21613400; PMCID: PMC3147916.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    30. N-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination. J Virol. 2011 May; 85(9):4510-9. Wang Y, Shao Q, Yu X, Kong W, Hildreth JE, Liu B. PMID: 21345952; PMCID: PMC3126286.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    31. Non-productive HIV-1 infection of human glomerular and urinary podocytes. Virology. 2010 Dec 05; 408(1):119-27. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 20937511; PMCID: PMC2970920.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    32. Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F. Virology. 2010 Apr 25; 400(1):68-75. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 20153011; PMCID: PMC2851184.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    33. Polyubiquitination of APOBEC3G is essential for its degradation by HIV-1 Vif. J Virol. 2010 May; 84(9):4840-4. Shao Q, Wang Y, Hildreth JE, Liu B. PMID: 20147392; PMCID: PMC2863731.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments. J Virol. 2009 Aug; 83(16):7982-95. Tang Y, Leao IC, Coleman EM, Broughton RS, Hildreth JE. PMID: 19474101; PMCID: PMC2715784.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    35. Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells. J Virol. 2009 Jan; 83(2):512-21. Khatua AK, Taylor HE, Hildreth JE, Popik W. PMID: 18987139; PMCID: PMC2612372.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    36. Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges. J Virol. 2008 Jul; 82(13):6591-9. Ambrose Z, Compton L, Piatak M, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN. PMID: 18434406; PMCID: PMC2447098.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    37. Delipidated retroviruses as potential autologous therapeutic vaccines--a pilot experiment. Exp Biol Med (Maywood). 2008 Jun; 233(6):732-40. Kitabwalla M, Ansari AA, Villinger F, Akeefe H, Conner AP, Mayne AE, Hildreth JE. PMID: 18408147.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    38. Cervicovaginal evaluation in macaques used as a model for topical microbicide safety studies. J Med Primatol. 2008 Feb; 37 Suppl 1:65-73. Scorpio DG, Ruben DS, Liao Z, Hildreth JE, Fletcher CA. PMID: 18269532.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    39. Production and characterization of a monoclonal antibody against Niemann Pick type C protein. Hybridoma (Larchmt). 2006 Aug; 25(4):216-24. Leao IC, Maciel M, Hildreth JE. PMID: 16934018.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    40. Lactobacilli-expressed single-chain variable fragment (scFv) specific for intercellular adhesion molecule 1 (ICAM-1) blocks cell-associated HIV-1 transmission across a cervical epithelial monolayer. J Immunol. 2006 May 01; 176(9):5627-36. Chancey CJ, Khanna KV, Seegers JF, Zhang GW, Hildreth J, Langan A, Markham RB. PMID: 16622032.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    41. Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J Cell Biol. 2006 Mar 13; 172(6):923-35. Booth AM, Fang Y, Fallon JK, Yang JM, Hildreth JE, Gould SJ. PMID: 16533950; PMCID: PMC2063735.
      View in: PubMed   Mentions: 290     Fields:    Translation:HumansCells
    42. Characterization of an anti-lymphocyte function-associated antigen-1 antibody in a simian immunodeficiency virus-pig-tailed macaque (Macaca nemestrina) model. Comp Med. 2006 Feb; 56(1):23-30. Fletcher CA, Liao Z, Adams RJ, Carter DL, Jones OD, Davis HG, Bryant JL, Hildreth JE. PMID: 16521856.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    43. Enhancement of cell mediated immune responses using lipid depleted lentivirus as immunogen: a novel approach for inducing recognition of new viral epitopes. Vaccine. 2005 Sep 07; 23(38):4666-77. Kitabwalla M, Villinger F, Akeefe H, Liao Z, Mayne AE, Gargano L, Conner AP, Maltais JA, Kunas G, Hildreth JE, Ansari AA, Bellotti M. PMID: 15955600.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    44. The evolution of alloimmunity and the genesis of adaptive immunity. Q Rev Biol. 2004 Dec; 79(4):359-82. Gould SJ, Hildreth JE, Booth AM. PMID: 15669770.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    45. Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions. J Virol. 2003 Dec; 77(24):13084-92. Mansharamani M, Graham DR, Monie D, Lee KK, Hildreth JE, Siliciano RF, Wilson KL. PMID: 14645565; PMCID: PMC296067.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    46. Evidence that HIV budding in primary macrophages occurs through the exosome release pathway. J Biol Chem. 2003 Dec 26; 278(52):52347-54. Nguyen DG, Booth A, Gould SJ, Hildreth JE. PMID: 14561735.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansCells
    47. The Trojan exosome hypothesis. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10592-7. Gould SJ, Booth AM, Hildreth JE. PMID: 12947040; PMCID: PMC196848.
      View in: PubMed   Mentions: 256     Fields:    Translation:Cells
    48. Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells. AIDS Res Hum Retroviruses. 2003 Aug; 19(8):675-87. Liao Z, Graham DR, Hildreth JE. PMID: 13678470.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCells
    49. Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts. J Virol. 2003 Aug; 77(15):8237-48. Graham DR, Chertova E, Hilburn JM, Arthur LO, Hildreth JE. PMID: 12857892; PMCID: PMC165256.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    50. Differential expression of human immunodeficiency virus coreceptors, by CEM, CEMVBL, and CEM E1000 cells. J Infect Dis. 2003 Mar 01; 187(5):874-5; author reply 875-6. Owen A, Chandler B, Ford J, Khoo S, Back D. PMID: 12599066.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    51. Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages. Eur J Immunol. 2003 Feb; 33(2):483-93. Nguyen DG, Hildreth JE. PMID: 12645947.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    52. Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS. AIDS Res Hum Retroviruses. 2002 Nov 01; 18(16):1197-205. Banks ND, Kinsey N, Clements J, Hildreth JE. PMID: 12487826.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    53. Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection. J Infect Dis. 2002 Aug 01; 186(3):332-40. Speck RR, Yu XF, Hildreth J, Flexner C. PMID: 12134229.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    54. Oligomers of glycamino acid. Bioorg Med Chem. 2002 Jun; 10(6):1999-2013. Suhara Y, Yamaguchi Y, Collins B, Schnaar RL, Yanagishita M, Hildreth JE, Shimada I, Ichikawa Y. PMID: 11937360.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    55. Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent. J Clin Invest. 2002 Jan; 109(2):205-11. Khanna KV, Whaley KJ, Zeitlin L, Moench TR, Mehrazar K, Cone RA, Liao Z, Hildreth JE, Hoen TE, Shultz L, Markham RB. PMID: 11805132; PMCID: PMC150835.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    56. Characterization of new syncytium-inhibiting monoclonal antibodies implicates lipid rafts in human T-cell leukemia virus type 1 syncytium formation. J Virol. 2001 Aug; 75(16):7351-61. Niyogi K, Hildreth JE. PMID: 11462007; PMCID: PMC114970.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    57. Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1. AIDS Res Hum Retroviruses. 2001 Jul 20; 17(11):1009-19. Liao Z, Cimakasky LM, Hampton R, Nguyen DH, Hildreth JE. PMID: 11485618.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansCells
    58. LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication. Virology. 2000 Aug 01; 273(2):307-15. Roos JW, Maughan MF, Liao Z, Hildreth JE, Clements JE. PMID: 10915601.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    59. CD4-independent, CCR5-dependent simian immunodeficiency virus infection and chemotaxis of human cells. J Virol. 2000 Aug; 74(15):6720-4. Iyengar S, Schwartz DH, Clements JE, Hildreth JE. PMID: 10888609; PMCID: PMC112187.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    60. High-affinity anti-ganglioside IgG antibodies raised in complex ganglioside knockout mice: reexamination of GD1a immunolocalization. J Neurochem. 2000 Jul; 75(1):404-12. Lunn MP, Johnson LA, Fromholt SE, Itonori S, Huang J, Vyas AA, Hildreth JE, Griffin JW, Schnaar RL, Sheikh KA. PMID: 10854286.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    61. Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J Virol. 2000 Apr; 74(7):3264-72. Nguyen DH, Hildreth JE. PMID: 10708443; PMCID: PMC111827.
      View in: PubMed   Mentions: 330     Fields:    Translation:HumansCells
    62. Increased infectivity of HIV type 1 particles bound to cell surface and solid-phase ICAM-1 and VCAM-1 through acquired adhesion molecules LFA-1 and VLA-4. AIDS Res Hum Retroviruses. 2000 Mar 01; 16(4):355-66. Liao Z, Roos JW, Hildreth JE. PMID: 10716373.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    63. Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha. J Immunol. 2000 Feb 01; 164(3):1408-15. Khanna KV, Yu XF, Ford DH, Ratner L, Hildreth JK, Markham RB. PMID: 10640756.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    64. Production and characterization of monoclonal antibodies against pigtailed macaque (Macaca nemestrina) cell adhesion molecules. Hybridoma. 1999 Oct; 18(5):437-47. Hildreth JE, Mankowski JL, Zink C, Clements JE. PMID: 10600031.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    65. CD56 identifies monocytes and not natural killer cells in rhesus macaques. Cytometry. 1999 Sep 01; 37(1):41-50. Carter DL, Shieh TM, Blosser RL, Chadwick KR, Margolick JB, Hildreth JE, Clements JE, Zink MC. PMID: 10451505.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    66. The channel-forming toxin aerolysin neutralizes human immunodeficiency virus type 1. Mol Microbiol. 1999 Aug; 33(3):659-66. Nguyen DH, Liao Z, Buckley JT, Hildreth JE. PMID: 10417655.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    67. T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: implications for HIV pathogenesis. J Immunol. 1999 May 15; 162(10):6263-7. Iyengar S, Schwartz DH, Hildreth JE. PMID: 10229873.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    68. Enhanced HIV type 1 neutralization by human anti-glycoprotein 120 monoclonal antibodies in the presence of monoclonal antibodies to lymphocyte function-associated molecule 1. AIDS Res Hum Retroviruses. 1999 Apr 10; 15(6):523-31. Hioe CE, Hildreth JE, Zolla-Pazner S. PMID: 10221529.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    69. Antibody-dependent cell-mediated cytotoxicity can protect PBMC from infection by cell-associated HIV-1. Clin Immunol. 1999 Feb; 90(2):203-12. Hildreth JE, Hampton R, Halsey NA. PMID: 10080832.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    70. Syncytium-inhibiting monoclonal antibodies produced against human T-cell lymphotropic virus type 1-infected cells recognize class II major histocompatibility complex molecules and block by protein crowding. J Virol. 1998 Dec; 72(12):9544-52. Hildreth JE. PMID: 9811687; PMCID: PMC110458.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    71. Role of cellular adhesion molecules in HIV type 1 infection and their impact on virus neutralization. AIDS Res Hum Retroviruses. 1998 Oct; 14 Suppl 3:S247-54. Hioe CE, Bastiani L, Hildreth JE, Zolla-Pazner S. PMID: 9814951.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    72. Immunoaffinity localization of the enzyme xanthine oxidase on the outside surface of the endothelial cell plasma membrane. Surgery. 1998 Sep; 124(3):551-60. Vickers S, Schiller HJ, Hildreth JE, Bulkley GB. PMID: 9736909.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    73. Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells. J Virol. 1998 Jun; 72(6):5251-5. Iyengar S, Hildreth JE, Schwartz DH. PMID: 9573299; PMCID: PMC110111.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    74. Human T-cell lymphotropic virus type 1 (HTLV-1)-induced syncytium formation mediated by vascular cell adhesion molecule-1: evidence for involvement of cell adhesion molecules in HTLV-1 biology. J Virol. 1997 Feb; 71(2):1173-80. Hildreth JE, Subramanium A, Hampton RA. PMID: 8995639; PMCID: PMC191170.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    75. Mutations in the matrix protein of human immunodeficiency virus type 1 inhibit surface expression and virion incorporation of viral envelope glycoproteins in CD4+ T lymphocytes. J Virol. 1997 Feb; 71(2):1443-52. Lee YM, Tang XB, Cimakasky LM, Hildreth JE, Yu XF. PMID: 8995670; PMCID: PMC191201.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    76. Antibody to human MHC class I inhibits SIVsmmPBj1.9-induced proliferation of pigtailed macaque lymphocytes. Exp Clin Immunogenet. 1997; 14(2):141-8. Baskar PV, Nagel JE, Narayan O, McClure HM, Adler WH, Hildreth JE. PMID: 9395890.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    77. Anti-HLA class I antibody inhibits Staphylococcus enterotoxin A (SEA)-induced proliferation of human PBMC. Cell Immunol. 1996 Aug 25; 172(1):135-8. Baskar P, Hildreth JE, Chrest FJ, Nagel JE, Adler WH. PMID: 8806816.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    78. Synthesis of sulfated ß-1,6-linked oligosaccharide mimetics: A novel potent inhibitor of HIV replication. Tetrahedron Letters. 1996 Apr 1; 37(15):2549-2552. Suhara SY, Ichikawa IM, Hildreth HJ, Ichikawa IY. .
      View in: Publisher Site   Mentions:
    79. Synthesis of a new carbohydrate mimetics: “carbopeptoid” containing a C-1 carboxylate and C-2 amino group. Tetrahedron Letters. 1996 Mar 1; 37(10):1575-1578. Suhara SY, Hildreth HJ, Ichikawa IY. .
      View in: Publisher Site   Mentions:
    80. Assessment of cell binding to hyaluronic acid in a solid-phase assay. Anal Biochem. 1996 Jan 15; 233(2):216-20. Guo MM, Hildreth JE. PMID: 8789721.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    81. Factors modifying protective effect of anti-CD18 antibodies on myocardial reperfusion injury in dogs. Am J Physiol. 1996 Jan; 270(1 Pt 2):H53-64. Perez RG, Arai M, Richardson C, DiPaula A, Siu C, Matsumoto N, Hildreth JE, Mariscalco MM, Smith CW, Becker LC. PMID: 8769734.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    82. HIV acquires functional adhesion receptors from host cells. AIDS Res Hum Retroviruses. 1995 Sep; 11(9):1007-13. Guo MM, Hildreth JE. PMID: 8554897.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    83. Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1. J Virol. 1995 Aug; 69(8):4628-32. Gomez MB, Hildreth JE. PMID: 7541842; PMCID: PMC189262.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    84. Targeted delivery of immunomicrospheres in vivo. Drug Delivery. 1995 Jan 1; 2(3-4):166-174. Truong TV, Williams WJ, Hildreth HJ, Leong LK. .
      View in: Publisher Site   Mentions:
    85. Presence in India of HIV type 1 similar to North American strains. AIDS Res Hum Retroviruses. 1994 Aug; 10(8):1039-41. Baskar PV, Ray SC, Rao R, Quinn TC, Hildreth JE, Bollinger RC. PMID: 7811535.
      View in: PubMed   Mentions: 11     Fields:    Translation:CellsPHPublic Health
    86. Simian immunodeficiency virus SIVsmmPBj 1.9 induces multinucleated giant cell formation in human peripheral blood monocytes. AIDS Res Hum Retroviruses. 1994 Jan; 10(1):73-80. Baskar P, Narayan O, McClure HM, Hildreth JE. PMID: 8179965.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    87. Human gallstones contain pronucleating nonmucin glycoproteins that are immunoglobulins. Ann Surg. 1994 Jan; 219(1):25-33. Lipsett PA, Hildreth J, Kaufman HS, Lillemoe KD, Pitt HA. PMID: 8297172; PMCID: PMC1243086.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    88. Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV. AIDS Res Hum Retroviruses. 1993 Nov; 9(11):1157-65. Orentas RJ, Hildreth JE. PMID: 8312057.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    89. HIV-induced loss of CD44 expression in monocytic cell lines. J Immunol. 1993 Aug 15; 151(4):2225-36. Guo MM, Hildreth JE. PMID: 8345206.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    90. Safety and immunogenicity of a recombinant protein influenza A vaccine in adult human volunteers and protective efficacy against wild-type H1N1 virus challenge. J Infect Dis. 1993 Mar; 167(3):593-601. Fries LF, Dillon SB, Hildreth JE, Karron RA, Funkhouser AW, Friedman CJ, Jones CS, Culleton VG, Clements ML. PMID: 8440931.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    91. A monoclonal antibody against a novel 20-kDa protein induces cell adhesion and cytoskeleton-dependent morphologic changes. J Immunol. 1992 Oct 15; 149(8):2549-59. Lin SL, Derr D, Hildreth JE. PMID: 1383318.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    92. Anti-class II MHC antibody induces multinucleated giant cell formation from peripheral blood monocytes. J Leukoc Biol. 1992 Mar; 51(3):199-209. Orentas RJ, Reinlib L, Hildreth JE. PMID: 1541903.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    93. 3-Deaza-adenosine and inhibition of HIV. Lancet. 1992 Feb 15; 339(8790):438. Flexner CW, Hildreth JE, Kuncl RW, Drachman DB. PMID: 1346708.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    94. CD63/Pltgp40: a platelet activation antigen identical to the stage-specific, melanoma-associated antigen ME491. Blood. 1991 Jul 15; 78(2):280-4. Azorsa DO, Hyman JA, Hildreth JE. PMID: 2070066.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    95. Characterization of a novel self-associating Mr 40,000 platelet glycoprotein. Blood. 1991 Jan 01; 77(1):121-32. Hildreth JE, Derr D, Azorsa DO. PMID: 1984792.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    96. IL-3 augments adhesiveness for endothelium and CD11b expression in human basophils but not neutrophils. J Immunol. 1990 Sep 15; 145(6):1832-7. Bochner BS, McKelvey AA, Sterbinsky SA, Hildreth JE, Derse CP, Klunk DA, Lichtenstein LM, Schleimer RP. PMID: 1697310.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    97. Induction of CD4+ human cytolytic T cells specific for HIV-infected cells by a gp160 subunit vaccine. Science. 1990 Jun 08; 248(4960):1234-7. Orentas RJ, Hildreth JE, Obah E, Polydefkis M, Smith GE, Clements ML, Siliciano RF. PMID: 2190315.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCellsPHPublic Health
    98. Homotypic cell aggregation induced by anti-CD44(Pgp-1) monoclonal antibodies and related to CD44(Pgp-1) expression. J Immunol. 1990 Mar 01; 144(5):1661-70. Belitsos PC, Hildreth JE, August JT. PMID: 1689752.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    99. Involvement of lymphocyte function-associated antigen-1 (LFA-1) but not ICAM-1 in a radioactive leukocyte cell-mediated immunity (LA-CMI) assay. J Clin Lab Immunol. 1990 Mar; 31(3):145-9. Fekete B, Hildreth JE, Holland JF, Bekesi JG. PMID: 1983768.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    100. Flow cytometric methods for the analysis of human basophil surface antigens and viability. J Immunol Methods. 1989 Dec 20; 125(1-2):265-71. Bochner BS, McKelvey AA, Schleimer RP, Hildreth JE, MacGlashan DW. PMID: 2607157.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    101. Production and characterization of monoclonal anti-CD18 anti-idiotype antibodies. Mol Immunol. 1989 Dec; 26(12):1155-67. Hildreth JE, Hyman JA. PMID: 2698997.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    102. Monoclonal antibodies against porcine LFA-1: species cross-reactivity and functional effects of beta-subunit-specific antibodies. Mol Immunol. 1989 Sep; 26(9):883-95. Hildreth JE, Holt V, August JT, Pescovitz MD. PMID: 2481234.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    103. Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation. Science. 1989 Jun 02; 244(4908):1075-8. Hildreth JE, Orentas RJ. PMID: 2543075.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    104. Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 1989 Jan; 268(1):360-78. Mane SM, Marzella L, Bainton DF, Holt VK, Cha Y, Hildreth JE, August JT. PMID: 2912382.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    105. The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor. EMBO J. 1987 Apr; 6(4):915-9. Law SK, Gagnon J, Hildreth JE, Wells CE, Willis AC, Wong AJ. PMID: 2954816; PMCID: PMC553482.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    106. Effects of monoclonal antibodies to the alpha and beta chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions. Eur J Immunol. 1985 Sep; 15(9):888-92. Dongworth DW, Gotch FM, Hildreth JE, Morris A, McMichael AJ. PMID: 3930261.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    107. A high-performance liquid chromatographic procedure for the purification of mouse monoclonal antibodies. Anal Biochem. 1985 Jun; 147(2):451-4. Deschamps JR, Hildreth JE, Derr D, August JT. PMID: 4014689.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    108. The human lymphocyte function-associated (HLFA) antigen and a related macrophage differentiation antigen (HMac-1): functional effects of subunit-specific monoclonal antibodies. J Immunol. 1985 May; 134(5):3272-80. Hildreth JE, August JT. PMID: 2580022.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    109. An HLA class I specific monoclonal antibody that fails to bind to all HLA-A antigens. Hum Immunol. 1985 May; 13(1):13-9. Ellis SA, Taylor C, Hildreth JE, McMichael AJ. PMID: 2580818.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    110. Plasma membranes from influenza virus-infected cells induce in vitro human secondary virus-specific cytotoxic T lymphocyte responses. Mol Biol Med. 1983 Sep; 1(2):225-33. Hildreth JE, Gotch FM, McMichael AJ. PMID: 6334215.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    111. A human lymphocyte-associated antigen involved in cell-mediated lympholysis. Eur J Immunol. 1983 Mar; 13(3):202-8. Hildreth JE, Gotch FM, Hildreth PD, McMichael AJ. PMID: 6339253.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    112. Identification of a human Ia antigen that is different from HLA-DR and DC antigens. Immunogenetics. 1983; 17(6):623-35. Makgoba MW, Hildreth JE, McMichael AJ. PMID: 6407986.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    113. Lysis of allogeneic human lymphocytes by nonspecifically activated T-like cells. Eur J Immunol. 1982 Dec; 12(12):1002-5. McMichael AJ, Gotch FM, Hildreth JE. PMID: 6984389.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    114. N-D-Gluco-N-methylalkanamide compounds, a new class of non-ionic detergents for membrane biochemistry. Biochem J. 1982 Nov 01; 207(2):363-6. Hildreth JE. PMID: 7159387; PMCID: PMC1153869.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    115. Monoclonal antibodies to Epstein-Barr virus-induced, transformation-associated cell surface antigens: binding patterns and effect upon virus-specific T-cell cytotoxicity. Int J Cancer. 1982 Apr 15; 29(4):373-81. Rowe M, Hildreth JE, Rickinson AB, Epstein MA. PMID: 6282762.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
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