James E Littlejohn

InstitutionUniversity of California Davis
CA 95817
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    1. Raiten JM, Wong ZZ, Spelde A, Littlejohn J, Augoustides JGT, Gutsche JT. Anticoagulation and Transfusion Therapy in Patients Requiring Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. 2017 06; 31(3):1051-1059. PMID: 27815114.
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    2. Rascoe PA, Jupiter D, Cao X, Littlejohn J, Smythe WR. Molecular pathogenesis of malignant mesothelioma. Expert Rev Mol Med. 2012 May 24; 14:e12. PMID: 22622048.
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    3. Zhang L, Littlejohn J, Cui Y, Cao X, Peddaboina C, Smythe WR. Characterization of bortezomib-adapted I-45 mesothelioma cells. Mol Cancer. 2010 May 18; 9:110. PMID: 20482802; PMCID: PMC2882347.
    4. Cao X, Littlejohn J, Rodarte C, Zhang L, Martino B, Rascoe P, Hamid K, Jupiter D, Smythe WR. Up-regulation of Bcl-xl by hepatocyte growth factor in human mesothelioma cells involves ETS transcription factors. Am J Pathol. 2009 Nov; 175(5):2207-16. PMID: 19834061; PMCID: PMC2774082.
    5. Littlejohn J, Cao X, Miller SD, Ozvaran MK, Jupiter D, Zhang L, Rodarte C, Smythe WR. Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. Int J Cancer. 2008 Jul 01; 123(1):202-8. PMID: 18360826.
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    6. Cao X, Rodarte C, Zhang L, Morgan CD, Littlejohn J, Smythe WR. Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma. Cancer Biol Ther. 2007 Feb; 6(2):246-52. PMID: 17224645.
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    7. Bumbaca D, Littlejohn J, Nayakanti H, Lucas AH, Rigden DJ, Galperin MY, Jedrzejas MJ. Genome-based identification and characterization of a putative mucin-binding protein from the surface of Streptococcus pneumoniae. Proteins. 2007 Feb 15; 66(3):547-58. PMID: 17115425.
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    8. Nukui M, Mello LV, Littlejohn J, Setlow B, Setlow P, Kim K, Leighton T, Jedrzejas MJ. Structure and molecular mechanism of Bacillus anthracis cofactor-independent phosphoglycerate mutase: a crucial enzyme for spores and growing cells of Bacillus species. Biophys J. 2007 Feb 01; 92(3):977-88. PMID: 17085493; PMCID: PMC1779985.
    9. Rigden DJ, Littlejohn J, Joshi HV, de Groot BL, Jedrzejas MJ. Alternate structural conformations of Streptococcus pneumoniae hyaluronan lyase: insights into enzyme flexibility and underlying molecular mechanism of action. J Mol Biol. 2006 May 12; 358(4):1165-78. PMID: 16569416.
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    10. Bumbaca D, Littlejohn J, Nayakanti H, Rigden DJ, Galperin MY, Jedrzejas MJ. Sequence analysis and characterization of a novel fibronectin-binding repeat domain from the surface of Streptococcus pneumoniae. OMICS. 2004; 8(4):341-56. PMID: 15703481.
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    11. Kolberg J, Aase A, Rødal G, Littlejohn J, Jedrzejas MJ. Epitope mapping of pneumococcal surface protein A of strain Rx1 using monoclonal antibodies and molecular structure modelling. FEMS Immunol Med Microbiol. 2003 Dec 05; 39(3):265-73. PMID: 14642312.
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    12. Rigden DJ, Lamani E, Mello LV, Littlejohn J, Jedrzejas MJ. Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling. J Mol Biol. 2003 May 09; 328(4):909-20. PMID: 12729763.
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    13. Rigden DJ, Littlejohn J, Henderson K, Jedrzejas MJ. Structures of phosphate and trivanadate complexes of Bacillus stearothermophilus phosphatase PhoE: structural and functional analysis in the cofactor-dependent phosphoglycerate mutase superfamily. J Mol Biol. 2003 Jan 17; 325(3):411-20. PMID: 12498792.
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