-
Spatial localization of endothelial cells in heterotypic spheroids influences Notch signaling. J Mol Med (Berl). 2020 03; 98(3):425-435.
Vorwald CE, Joshee S, Leach JK. PMID: 32020237; PMCID: PMC7083693.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Tunneling nanotubes mediate the expression of senescence markers in mesenchymal stem/stromal cell spheroids. Stem Cells. 2020 01; 38(1):80-89.
Whitehead J, Zhang J, Harvestine JN, Kothambawala A, Liu GY, Leach JK. PMID: 31298767; PMCID: PMC6954984.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Bio-instructive materials for musculoskeletal regeneration. Acta Biomater. 2019 09 15; 96:20-34.
Gonzalez-Fernandez T, Sikorski P, Leach JK. PMID: 31302298; PMCID: PMC6717669.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Is Tissue Engineering Helping Orthopaedic Care in Trauma? J Orthop Trauma. 2019 Jun; 33 Suppl 6:S12-S19.
Crist BD, Leach JK, Lee MA. PMID: 31083143.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Conditioning of myoblast secretome using mesenchymal stem/stromal cell spheroids improves bone repair. Bone. 2019 08; 125:151-159.
Saiz AM, Gionet-Gonzales MA, Lee MA, Leach JK. PMID: 31102712; PMCID: PMC6589400.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Cell-secreted extracellular matrix influences cellular composition sequestered from unprocessed bone marrow aspirate for osteogenic grafts. Biomater Sci. 2019 Apr 23; 7(5):2091-2101.
Harvestine JN, Saiz Jr AM, Leach JK. PMID: 30869662; PMCID: PMC6478553.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Non-destructive detection of matrix stabilization correlates with enhanced mechanical properties of self-assembled articular cartilage. J Tissue Eng Regen Med. 2019 04; 13(4):637-648.
Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA. PMID: 30770656; PMCID: PMC6461514.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Injectable mineralized microsphere-loaded composite hydrogels for bone repair in a sheep bone defect model. Biomaterials. 2019 03; 197:119-128.
Ingavle GC, Gionet-Gonzales M, Vorwald CE, Bohannon LK, Clark K, Galuppo LD, Leach JK. PMID: 30641263; PMCID: PMC6363840.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Detection of glycosaminoglycan loss in articular cartilage by fluorescence lifetime imaging. J Biomed Opt. 2018 12; 23(12):1-8.
Zhou X, Haudenschild AK, Sherlock BE, Hu JC, Leach JK, Athanasiou KA, Marcu L. PMID: 30578627; PMCID: PMC8357192.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Direct Observation of Tunneling Nanotubes within Human Mesenchymal Stem Cell Spheroids. J Phys Chem B. 2018 11 01; 122(43):9920-9926.
Zhang J, Whitehead J, Liu Y, Yang Q, Leach JK, Liu GY. PMID: 30350968.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Defining hydrogel properties to instruct lineage- and cell-specific mesenchymal differentiation. Biomaterials. 2019 01; 189:1-10.
Hung BP, Harvestine JN, Saiz AM, Gonzalez-Fernandez T, Sahar DE, Weiss ML, Leach JK. PMID: 30384124; PMCID: PMC6237198.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
In Vitro Models for Studying Transport Across Epithelial Tissue Barriers. Ann Biomed Eng. 2019 Jan; 47(1):1-21.
Arumugasaamy N, Navarro J, Kent Leach J, Kim PCW, Fisher JP. PMID: 30218224.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Exogenous Lysyl Oxidase-Like 2 and Perfusion Culture Induce Collagen Crosslink Formation in Osteogenic Grafts. Biotechnol J. 2019 Mar; 14(3):e1700763.
Mitra D, Yasui OW, Harvestine JN, Link JM, Hu JC, Athanasiou KA, Leach JK. PMID: 30052320; PMCID: PMC6432926.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties. Eur Cell Mater. 2018 07 27; 36:30-43.
Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA. PMID: 30051455.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Hypoxic Preconditioning of Mesenchymal Stem Cells with Subsequent Spheroid Formation Accelerates Repair of Segmental Bone Defects. Stem Cells. 2018 09; 36(9):1393-1403.
Ho SS, Hung BP, Heyrani N, Lee MA, Leach JK. PMID: 29968952; PMCID: PMC6125201.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Engineering principles for guiding spheroid function in the regeneration of bone, cartilage, and skin. Biomed Mater. 2018 03 21; 13(3):034109.
Gionet-Gonzales MA, Leach JK. PMID: 29460842; PMCID: PMC5898817.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Nondestructive assessment of collagen hydrogel cross-linking using time-resolved autofluorescence imaging. J Biomed Opt. 2018 03; 23(3):1-9.
Sherlock BE, Harvestine JN, Mitra D, Haudenschild A, Hu J, Athanasiou KA, Leach JK, Marcu L. PMID: 29512359; PMCID: PMC5839417.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
High-Throughput Formation of Mesenchymal Stem Cell Spheroids and Entrapment in Alginate Hydrogels. Methods Mol Biol. 2018; 1758:139-149.
Vorwald CE, Ho SS, Whitehead J, Leach JK. PMID: 29679328; PMCID: PMC6764926.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
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Cell Migration and Bone Formation from Mesenchymal Stem Cell Spheroids in Alginate Hydrogels Are Regulated by Adhesive Ligand Density. Biomacromolecules. 2017 Dec 11; 18(12):4331-4340.
Ho SS, Keown AT, Addison B, Leach JK. PMID: 29131587; PMCID: PMC5971090.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Engineering fibrin hydrogels to promote the wound healing potential of mesenchymal stem cell spheroids. Acta Biomater. 2017 12; 64:176-186.
Murphy KC, Whitehead J, Zhou D, Ho SS, Leach JK. PMID: 28987783; PMCID: PMC5682213.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
The Effects of Adipose-Derived Stem Cells Differentiated Into Endothelial Cells and Osteoblasts on Healing of Critical Size Calvarial Defects. J Craniofac Surg. 2017 Oct; 28(7):1874-1879.
Orbay H, Busse B, Leach JK, Sahar DE. PMID: 28872512.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Bioreactor culture duration of engineered constructs influences bone formation by mesenchymal stem cells. Biomaterials. 2017 Nov; 146:29-39.
Mitra D, Whitehead J, Yasui OW, Leach JK. PMID: 28898756; PMCID: PMC5618709.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Supersonic transient magnetic resonance elastography for quantitative assessment of tissue elasticity. Phys Med Biol. 2017 05 21; 62(10):4083-4106.
Liu Y, Liu J, Fite BZ, Foiret J, Ilovitsh A, Leach JK, Dumont E, Caskey CF, Ferrara KW. PMID: 28426437; PMCID: PMC5545104.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Multifactorial Experimental Design to Optimize the Anti-Inflammatory and Proangiogenic Potential of Mesenchymal Stem Cell Spheroids. Stem Cells. 2017 06; 35(6):1493-1504.
Murphy KC, Whitehead J, Falahee PC, Zhou D, Simon SI, Leach JK. PMID: 28276602; PMCID: PMC5446296.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Measurement of oxygen tension within mesenchymal stem cell spheroids. J R Soc Interface. 2017 02; 14(127).
Murphy KC, Hung BP, Browne-Bourne S, Zhou D, Yeung J, Genetos DC, Leach JK. PMID: 28179546; PMCID: PMC5332570.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Extracellular Matrix-Coated Composite Scaffolds Promote Mesenchymal Stem Cell Persistence and Osteogenesis. Biomacromolecules. 2016 11 14; 17(11):3524-3531.
Harvestine JN, Vollmer NL, Ho SS, Zikry CA, Lee MA, Leach JK. PMID: 27744699.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Effect of encapsulation on plasminogen activator delivery to the microcirculation and its implications for bleeding. Clin Hemorheol Microcirc. 2016 Oct 05; 63(4):373-379.
Thummala AS, Leach JK, Patterson E, O'Rear EA. PMID: 26890102.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
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Bone Morphogenetic Protein-2 Promotes Human Mesenchymal Stem Cell Survival and Resultant Bone Formation When Entrapped in Photocrosslinked Alginate Hydrogels. Adv Healthc Mater. 2016 10; 5(19):2501-2509.
Ho SS, Vollmer NL, Refaat MI, Jeon O, Alsberg E, Lee MA, Leach JK. PMID: 27581621; PMCID: PMC5176258.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Binding to COMP Reduces the BMP2 Dose for Spinal Fusion in a Rat Model. Spine (Phila Pa 1976). 2016 Jul 15; 41(14):E829-E836.
Refaat M, Klineberg EO, Fong MC, Garcia TC, Leach JK, Haudenschild DR. PMID: 26679888; PMCID: PMC7054986.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α2β1 Signaling. Stem Cells Transl Med. 2016 09; 5(9):1229-37.
Murphy KC, Hoch AI, Harvestine JN, Zhou D, Leach JK. PMID: 27365484; PMCID: PMC4996446.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Increased Survival and Function of Mesenchymal Stem Cell Spheroids Entrapped in Instructive Alginate Hydrogels. Stem Cells Transl Med. 2016 Jun; 5(6):773-81.
Ho SS, Murphy KC, Binder BY, Vissers CB, Leach JK. PMID: 27057004; PMCID: PMC4878334.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
-
Cell-secreted matrices perpetuate the bone-forming phenotype of differentiated mesenchymal stem cells. Biomaterials. 2016 Jan; 74:178-87.
Hoch AI, Mittal V, Mitra D, Vollmer N, Zikry CA, Leach JK. PMID: 26457835; PMCID: PMC4661076.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Hydrogel biophysical properties instruct coculture-mediated osteogenic potential. FASEB J. 2016 Jan; 30(1):477-86.
Murphy KC, Stilhano RS, Mitra D, Zhou D, Batarni S, Silva EA, Leach JK. PMID: 26443826; PMCID: PMC4684517.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Lysophosphatidic Acid and Sphingosine-1-Phosphate: A Concise Review of Biological Function and Applications for Tissue Engineering. Tissue Eng Part B Rev. 2015 Dec; 21(6):531-42.
Binder BY, Williams PA, Silva EA, Leach JK. PMID: 26035484; PMCID: PMC4663652.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Reduced serum and hypoxic culture conditions enhance the osteogenic potential of human mesenchymal stem cells. Stem Cell Rev Rep. 2015 Jun; 11(3):387-93.
Binder BY, Sagun JE, Leach JK. PMID: 25173881; PMCID: PMC4345153.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Engineered Fibrin Gels for Parallel Stimulation of Mesenchymal Stem Cell Proangiogenic and Osteogenic Potential. Ann Biomed Eng. 2015 Aug; 43(8):2010-21.
Murphy KC, Hughbanks ML, Binder BY, Vissers CB, Leach JK. PMID: 25527322; PMCID: PMC4475511.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Implantable biomaterial based on click chemistry for targeting small molecules. Acta Biomater. 2014 Dec; 10(12):5099-5105.
Mejía Oneto JM, Gupta M, Leach JK, Lee M, Sutcliffe JL. PMID: 25162537.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Human mesenchymal stem cell spheroids in fibrin hydrogels exhibit improved cell survival and potential for bone healing. Cell Tissue Res. 2014 Jul; 357(1):91-9.
Murphy KC, Fang SY, Leach JK. PMID: 24781147; PMCID: PMC4077909.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
Ultrastructure and growth factor content of equine platelet-rich fibrin gels. Am J Vet Res. 2014 Apr; 75(4):392-401.
Textor JA, Murphy KC, Leach JK, Tablin F. PMID: 24669926.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Concise review: optimizing expansion of bone marrow mesenchymal stem/stromal cells for clinical applications. Stem Cells Transl Med. 2014 May; 3(5):643-52.
Hoch AI, Leach JK. PMID: 24682286; PMCID: PMC4006491.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Redirection of neurite outgrowth by coupling chondroitin sulfate proteoglycans to polymer membranes. Ann Biomed Eng. 2014 Jun; 42(6):1271-81.
Man AJ, Leach JK, Bannerman P. PMID: 24570390.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis. Tissue Eng Part A. 2014 Apr; 20(7-8):1156-64.
Binder BY, Genetos DC, Leach JK. PMID: 24131310; PMCID: PMC3993074.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Enhanced trophic factor secretion by mesenchymal stem/stromal cells with Glycine-Histidine-Lysine (GHK)-modified alginate hydrogels. Acta Biomater. 2014 May; 10(5):1955-64.
Jose S, Hughbanks ML, Binder BY, Ingavle GC, Leach JK. PMID: 24468583; PMCID: PMC3976757.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Lysophosphatidic acid enhances stromal cell-directed angiogenesis. PLoS One. 2013; 8(12):e82134.
Binder BY, Sondergaard CS, Nolta JA, Leach JK. PMID: 24312635; PMCID: PMC3846884.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Advancements in electrospinning of polymeric nanofibrous scaffolds for tissue engineering. Tissue Eng Part B Rev. 2014 Aug; 20(4):277-93.
Ingavle GC, Leach JK. PMID: 24004443.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Alginate hydrogels containing cell-interactive beads for bone formation. FASEB J. 2013 Dec; 27(12):4844-52.
Bhat A, Hoch AI, Decaris ML, Leach JK. PMID: 24005905.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Remineralization of demineralized bone matrix (DBM) via alternating solution immersion (ASI). J Mech Behav Biomed Mater. 2013 Oct; 26:109-18.
Soicher MA, Christiansen BA, Stover SM, Leach JK, Fyhrie DP. PMID: 23759125; PMCID: PMC3713112.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Enhancing osteoconductivity of fibrin gels with apatite-coated polymer microspheres. Tissue Eng Part A. 2013 Aug; 19(15-16):1773-82.
Davis HE, Binder BY, Schaecher P, Yakoobinsky DD, Bhat A, Leach JK. PMID: 23560390; PMCID: PMC3700018.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
A reproducible, high throughput method for fabricating fibrin gels. BMC Res Notes. 2012 Aug 08; 5:423.
Murphy KC, Leach JK. PMID: 22873708; PMCID: PMC3492004.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Cell-derived matrix coatings for polymeric scaffolds. Tissue Eng Part A. 2012 Oct; 18(19-20):2148-57.
Decaris ML, Binder BY, Soicher MA, Bhat A, Leach JK. PMID: 22651377.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Bioceramic-mediated trophic factor secretion by mesenchymal stem cells enhances in vitro endothelial cell persistence and in vivo angiogenesis. Tissue Eng Part A. 2012 Jul; 18(13-14):1520-8.
He J, Decaris ML, Leach JK. PMID: 22546052; PMCID: PMC3397122.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells. PLoS One. 2012; 7(4):e35579.
Hoch AI, Binder BY, Genetos DC, Leach JK. PMID: 22536411; PMCID: PMC3334972.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Transferable cell-secreted extracellular matrices enhance osteogenic differentiation. Acta Biomater. 2012 Feb; 8(2):744-52.
Decaris ML, Mojadedi A, Bhat A, Leach JK. PMID: 22079209.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Differential growth factor adsorption to calvarial osteoblast-secreted extracellular matrices instructs osteoblastic behavior. PLoS One. 2011; 6(10):e25990.
Bhat A, Boyadjiev SA, Senders CW, Leach JK. PMID: 21998741; PMCID: PMC3187840.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Neurite outgrowth in fibrin gels is regulated by substrate stiffness. Tissue Eng Part A. 2011 Dec; 17(23-24):2931-42.
Man AJ, Davis HE, Itoh A, Leach JK, Bannerman P. PMID: 21882895.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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The role of protein solubilization in antigen removal from xenogeneic tissue for heart valve tissue engineering. Biomaterials. 2011 Nov; 32(32):8129-38.
Wong ML, Leach JK, Athanasiou KA, Griffiths LG. PMID: 21810537.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
Osteogenic response to BMP-2 of hMSCs grown on apatite-coated scaffolds. Biotechnol Bioeng. 2011 Nov; 108(11):2727-35.
Davis HE, Case EM, Miller SL, Genetos DC, Leach JK. PMID: 21656707; PMCID: PMC3178749.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Noninvasive multimodal evaluation of bioengineered cartilage constructs combining time-resolved fluorescence and ultrasound imaging. Tissue Eng Part C Methods. 2011 Apr; 17(4):495-504.
Fite BZ, Decaris M, Sun Y, Sun Y, Lam A, Ho CK, Leach JK, Marcu L. PMID: 21303258; PMCID: PMC3065732.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation. Ann Biomed Eng. 2011 Apr; 39(4):1174-85.
Decaris ML, Leach JK. PMID: 21120695; PMCID: PMC3069311.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood, and umbilical cord tissue. Am J Vet Res. 2010 Oct; 71(10):1237-45.
Toupadakis CA, Wong A, Genetos DC, Cheung WK, Borjesson DL, Ferraro GL, Galuppo LD, Leach JK, Owens SD, Yellowley CE. PMID: 20919913.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Supplementation of fibrin gels with sodium chloride enhances physical properties and ensuing osteogenic response. Acta Biomater. 2011 Feb; 7(2):691-9.
Davis HE, Miller SL, Case EM, Leach JK. PMID: 20837168.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Biomineralized composite substrates increase gene expression with nonviral delivery. J Biomed Mater Res A. 2010 Aug; 94(2):344-54.
Rao RR, He J, Leach JK. PMID: 20186740.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Designing bioactive delivery systems for tissue regeneration. Ann Biomed Eng. 2011 Jan; 39(1):1-13.
Davis HE, Leach JK. PMID: 20676773; PMCID: PMC3010216.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Osteogenic comparison of expanded and uncultured adipose stromal cells. Cytotherapy. 2010 Jul; 12(4):554-62.
Cheung WK, Working DM, Galuppo LD, Leach JK. PMID: 20370353.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Oxygen tension differentially influences osteogenic differentiation of human adipose stem cells in 2D and 3D cultures. J Cell Biochem. 2010 May; 110(1):87-96.
He J, Genetos DC, Yellowley CE, Leach JK. PMID: 20213746.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Oxygen tension modulates neurite outgrowth in PC12 cells through a mechanism involving HIF and VEGF. J Mol Neurosci. 2010 Mar; 40(3):360-6.
Genetos DC, Cheung WK, Decaris ML, Leach JK. PMID: 20107925; PMCID: PMC2825316.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Osteogenesis and trophic factor secretion are influenced by the composition of hydroxyapatite/poly(lactide-co-glycolide) composite scaffolds. Tissue Eng Part A. 2010 Jan; 16(1):127-37.
He J, Genetos DC, Leach JK. PMID: 19642853; PMCID: PMC2811060.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Biomimetic scaffolds fabricated from apatite-coated polymer microspheres. J Biomed Mater Res A. 2009 Sep 15; 90(4):1021-31.
Davis HE, Rao RR, He J, Leach JK. PMID: 18655148.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Angiogenic response to bioactive glass promotes bone healing in an irradiated calvarial defect. Tissue Eng Part A. 2009 Apr; 15(4):877-85.
Leu A, Stieger SM, Dayton P, Ferrara KW, Leach JK. PMID: 18795867; PMCID: PMC2992393.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
-
Influence of the oxygen microenvironment on the proangiogenic potential of human endothelial colony forming cells. Angiogenesis. 2009; 12(4):303-11.
Decaris ML, Lee CI, Yoder MC, Tarantal AF, Leach JK. PMID: 19544080; PMCID: PMC2778716.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials. 2008 Jul; 29(19):2884-90.
Rocha FG, Sundback CA, Krebs NJ, Leach JK, Mooney DJ, Ashley SW, Vacanti JP, Whang EE. PMID: 18396329; PMCID: PMC2685178.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
-
Synthetic extracellular matrices for tissue engineering. Pharm Res. 2008 May; 25(5):1209-11.
Leach JK, Mooney DJ. PMID: 18266090.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
Proangiogenic potential of a collagen/bioactive glass substrate. Pharm Res. 2008 May; 25(5):1222-9.
Leu A, Leach JK. PMID: 18049878.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Modifying the proliferative state of target cells to control DNA expression and identifying cell types transfected in vivo. Mol Ther. 2007 Feb; 15(2):361-8.
Riddle KW, Kong HJ, Leach JK, Fischbach C, Cheung C, Anseth KS, Mooney DJ. PMID: 17235315.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Tissue engineering of a small hand phalanx with a porously casted polylactic acid-polyglycolic acid copolymer. Tissue Eng. 2006 Sep; 12(9):2675-83.
Sedrakyan S, Zhou ZY, Perin L, Leach K, Mooney D, Kim TH. PMID: 16995801.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Multifunctional cell-instructive materials for tissue regeneration. Regen Med. 2006 Jul; 1(4):447-55.
Leach JK. PMID: 17465837.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. Biomaterials. 2006 Jun; 27(17):3249-55.
Leach JK, Kaigler D, Wang Z, Krebsbach PH, Mooney DJ. PMID: 16490250.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater. 2005 Jun; 4(6):460-4.
Kong HJ, Liu J, Riddle K, Matsumoto T, Leach K, Mooney DJ. PMID: 15895097.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
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Distributed intraclot thrombolysis: mechanism of accelerated thrombolysis with encapsulated plasminogen activators. J Thromb Haemost. 2004 Sep; 2(9):1548-55.
Leach JK, Patterson E, O'Rear EA. PMID: 15333029.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Bone engineering by controlled delivery of osteoinductive molecules and cells. Expert Opin Biol Ther. 2004 Jul; 4(7):1015-27.
Leach JK, Mooney DJ. PMID: 15268670.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Encapsulation of a plasminogen activator speeds reperfusion, lessens infarct and reduces blood loss in a canine model of coronary artery thrombosis. Thromb Haemost. 2004 Jun; 91(6):1213-8.
Leach JK, Patterson E, O'Rear EA. PMID: 15175809.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Improving thrombolysis with encapsulated plasminogen activators and clinical relevance to myocardial infarction and stroke. Clin Hemorheol Microcirc. 2004; 30(3-4):225-8.
Leach JK, Patterson E, O'Rear EA. PMID: 15258347.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Accelerated thrombolysis in a rabbit model of carotid artery thrombosis with liposome-encapsulated and microencapsulated streptokinase. Thromb Haemost. 2003 Jul; 90(1):64-70.
Leach JK, O'Rear EA, Patterson E, Miao Y, Johnson AE. PMID: 12876627.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Factors affecting the particle size and in vitro release of bovine serum albumin from polyethylene glycol microparticles. Biomed Sci Instrum. 2003; 39:318-23.
Thummala AS, Leach JK, O'Rear EA. PMID: 12724913.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Investigation of deformability, viscosity, and aggregation of mPEG-modified erythrocytes. Biomed Sci Instrum. 2002; 38:333-8.
Leach JK, Hinman A, O'Rear EA. PMID: 12085627.
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PubMed Mentions:
1 Fields:
Translation:
Humans