Karen J Doyle

InstitutionUniversity of California Davis
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    1. Bailey D, Kirby BP, Atkinson J, Fixon-Owoo S, Henman MC, Shaw GG, Doyle K. Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation. Pharmacol Biochem Behav. 2015 Jun; 133:57-64. PMID: 25824983.
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    2. Wang W, Flores MC, Sihn CR, Kim HJ, Zhang Y, Doyle K, Chiamvimonvat N, Zhang XD, Yamoah EN. Identification of a key residue in Kv7.1 potassium channel essential for sensing external potassium ions. J Gen Physiol. 2015 Mar; 145(3):201-12. PMID: 25712016; PMCID: PMC4338162.
    3. Zhang XD, Lee JH, Lv P, Chen WC, Kim HJ, Wei D, Wang W, Sihn CR, Doyle K, Rock JR, Chiamvimonvat N, Yamoah EN. Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16A. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2575-80. PMID: 25675481; PMCID: PMC4345570.
    4. Lv P, Kim HJ, Lee JH, Sihn CR, Fathabad Gharaie S, Mousavi-Nik A, Wang W, Wang HG, Gratton MA, Doyle K, Zhang XD, Chiamvimonvat N, Yamoah EN. Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons. J Neurosci. 2014 May 21; 34(21):7383-93. PMID: 24849370; PMCID: PMC4028507.
    5. Wang W, Kim HJ, Lee JH, Wong V, Sihn CR, Lv P, Perez Flores MC, Mousavi-Nik A, Doyle K, Xu Y, Yamoah EN. Functional significance of K+ channel ß-subunit KCNE3 in auditory neurons. J Biol Chem. 2014 Jun 13; 289(24):16802-13. PMID: 24727472; PMCID: PMC4059123.
    6. Kim HJ, Gratton MA, Lee JH, Perez Flores MC, Wang W, Doyle K, Beermann F, Crognale MA, Yamoah EN. Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct. J Neurosci. 2013 Sep 04; 33(36):14601-6. PMID: 24005310; PMCID: PMC3761058.
    7. Butler RK, Ford GK, Hogan M, Roche M, Doyle K, Kelly JP, Kendall DA, Chapman V, Finn DP. Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. J Psychopharmacol. 2012 Jan; 26(1):83-91. PMID: 21926424.
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    8. Wang X, Levic S, Gratton MA, Doyle K, Yamoah EN, Pegg AE. Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine. J Biol Chem. 2009 Jan 09; 284(2):930-7. PMID: 19001365; PMCID: PMC2613633.
    9. Diaz RC, Vazquez AE, Dou H, Wei D, Cardell EL, Lingrel J, Shull GE, Doyle K, Yamoah EN. Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1. J Assoc Res Otolaryngol. 2007 Dec; 8(4):422-34. PMID: 17674100; PMCID: PMC2538340.
    10. Li J, Henman MC, Atkinson J, Fixon-Owoo S, Tatlisumak T, Shaw GG, Doyle K. The pre-ischaemic neuroprotective effects of the polyamine analogues BU43b and BU36b in permanent and transient focal cerebral ischaemia models in mice. Brain Res. 2006 Mar 03; 1076(1):209-15. PMID: 16473330.
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    11. Nie L, Feng W, Diaz R, Gratton MA, Doyle K, Yamoah EN. Functional consequences of polyamine synthesis inhibition by L-alpha-difluoromethylornithine (DFMO): cellular mechanisms for DFMO-mediated ototoxicity. J Biol Chem. 2005 Apr 15; 280(15):15097-102. PMID: 15718247.
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    12. Doyle K, Kirby BP, Murphy D, Shaw GG. Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo. Neurosci Lett. 2005 Jun 03; 380(3):247-51. PMID: 15862895.
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    13. Li J, Henman MC, Doyle K, Strbian D, Kirby BP, Tatlisumak T, Shaw GG. The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice. Brain Res. 2004 Dec 10; 1029(1):84-92. PMID: 15533319.
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    14. Doyle K, Bauch C, Battista R, Beatty C, Hughes GB, Mason J, Maw J, Musiek FL. Intratympanic steroid treatment: a review. Otol Neurotol. 2004 Nov; 25(6):1034-9. PMID: 15547441.
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    15. Smith MC, Tinling S, Doyle K. Difluoromethylornithine-induced reversible hearing loss across a wide frequency range. Laryngoscope. 2004 Jun; 114(6):1113-7. PMID: 15179223.
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    16. Doyle K, Kong YY, Strobel K, Dallaire P, Ray RM. Neonatal middle ear effusion predicts chronic otitis media with effusion. Otol Neurotol. 2004 May; 25(3):318-22. PMID: 15129112.
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    17. Rosenfeld RM, Culpepper L, Doyle K, Grundfast KM, Hoberman A, Kenna MA, Lieberthal AS, Mahoney M, Wahl RA, Woods CR, Yawn B. Clinical practice guideline: Otitis media with effusion. Otolaryngol Head Neck Surg. 2004 May; 130(5 Suppl):S95-118. PMID: 15138413.
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    18. Doyle K, Ray RM. The otolaryngologist's role in management of hearing loss in infancy and childhood. Ment Retard Dev Disabil Res Rev. 2003; 9(2):94-102. PMID: 12784227.
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    19. Doyle K, Burggraaff B, Fujikawa S, Kim J, Macarthur CJ. Neonatal Hearing Screening with Otoscopy, Auditory Brain Stem Response, and Otoacoustic Emissions. Otolaryngol Head Neck Surg. 1997 Jun; 116(6):597-603. PMID: 29389264.
      View in: PubMed
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