Ken Kaplan

InstitutionUniversity of California Davis
Address204A Briggs Hall
CA 95616
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    1. Davies AE, Kortright K, Kaplan K. Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics. Oncotarget. 2015 Sep 22; 6(28):25202-16. PMID: 26320184; PMCID: PMC4694825.
    2. Kaplan K, Li R. A prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptation. Trends Cell Biol. 2012 Nov; 22(11):576-83. PMID: 22959309; PMCID: PMC3479336.
    3. Rozelle DK, Hansen SD, Kaplan K. Chromosome passenger complexes control anaphase duration and spindle elongation via a kinesin-5 brake. J Cell Biol. 2011 Apr 18; 193(2):285-94. PMID: 21482719; PMCID: PMC3080259.
    4. Davies AE, Kaplan K. Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. J Cell Biol. 2010 Apr 19; 189(2):261-74. PMID: 20404110; PMCID: PMC2856898.
    5. Caldwell CM, Kaplan K. The role of APC in mitosis and in chromosome instability. Adv Exp Med Biol. 2009; 656:51-64. PMID: 19928352.
      View in: PubMed
    6. Caldwell CM, Green RA, Kaplan K. APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J Cell Biol. 2007 Sep 24; 178(7):1109-20. PMID: 17893240; PMCID: PMC2064647.
    7. Thomas S, Kaplan K. A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase. Mol Biol Cell. 2007 Oct; 18(10):3820-34. PMID: 17652458; PMCID: PMC1995702.
    8. Catlett MG, Kaplan K. Sgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p. J Biol Chem. 2006 Nov 03; 281(44):33739-48. PMID: 16945921.
      View in: PubMed
    9. Gillis AN, Thomas S, Hansen SD, Kaplan K. A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis. J Cell Biol. 2005 Dec 05; 171(5):773-84. PMID: 16330709; PMCID: PMC2171293.
    10. Green RA, Wollman R, Kaplan K. APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol Biol Cell. 2005 Oct; 16(10):4609-22. PMID: 16030254; PMCID: PMC1237068.
    11. Lingelbach LB, Kaplan K. The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly. Mol Cell Biol. 2004 Oct; 24(20):8938-50. PMID: 15456868; PMCID: PMC517876.
    12. Rodrigo-Brenni MC, Thomas S, Bouck DC, Kaplan K. Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function. Mol Biol Cell. 2004 Jul; 15(7):3366-78. PMID: 15090617; PMCID: PMC452590.
    13. Green RA, Kaplan K. Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J Cell Biol. 2003 Dec 08; 163(5):949-61. PMID: 14662741; PMCID: PMC2173599.
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