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Kyriacos A Athanasiou

TitleProfessor
InstitutionUniversity of California Davis
DepartmentOrthopaedic Surgery
Address1202 GBSF
CA 95616
Phone530-752-7193
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Engineering biomimetic knee menisci with zonal and anisotropic variations
    NIH/NIAMS R01AR071457Mar 1, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Self-assembling process in tissue engineering of articular cartilage
    NIH/NIAMS R01AR067821Jun 1, 2015 - May 31, 2020
    Role: Principal Investigator
    Engineering Lubrication in Tissue Engineered Cartilage
    NIH/NIAMS R01AR061496Aug 1, 2011 - Jun 30, 2015
    Role: Co-Principal Investigator
    Regenerating the fibrocartilage spectrum of the TMJ: from disc to condyle
    NIH/NIDCR R01DE019666May 5, 2010 - Feb 28, 2014
    Role: Principal Investigator
    Evaluation of TEC-Ari? Using MSCs to Engineer Articular Cartilage
    NIH/NIAMS R41AR053790Aug 1, 2008 - Jul 31, 2010
    Role: Principal Investigator
    Self-Assembling Process in Tissue Engineering of Articular Cartilage
    NIH/NIAMS R01AR053286Apr 1, 2007 - Feb 28, 2013
    Role: Principal Investigator
    TMJ Disc Regeneration
    NIH/NIDCR R01DE015038Jul 1, 2003 - May 31, 2023
    Role: Principal Investigator
    Toward tissue engineering of the knee meniscus
    NIH/NIAMS R01AR047839Dec 10, 2002 - Aug 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mitra D, Yasui OW, Harvestine JN, Link JM, Hu JC, Athanasiou KA, Leach JK. Exogenous lysyl oxidase-like 2 and perfusion culture induce collagen crosslink formation in osteogenic grafts. Biotechnol J. 2018 Jul 27; e1700763. PMID: 30052320.
      View in: PubMed
    2. Vapniarsky N, Huwe LW, Arzi B, Houghton MK, Wong ME, Wilson JW, Hatcher DC, Hu JC, Athanasiou KA. Tissue engineering toward temporomandibular joint disc regeneration. Sci Transl Med. 2018 Jun 20; 10(446). PMID: 29925634.
      View in: PubMed
    3. Huang BJ, Brown WE, Keown T, Hu JC, Athanasiou KA. Overcoming challenges in engineering large, scaffold-free neocartilage with functional properties. Tissue Eng Part A. 2018 May 16. PMID: 29766751.
      View in: PubMed
    4. Salinas EY, Hu JC, Athanasiou K. A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties. Tissue Eng Part B Rev. 2018 Apr 26. PMID: 29562835.
      View in: PubMed
    5. Brown WE, Huey DJ, Hu JC, Athanasiou KA. Functional self-assembled neocartilage as part of a biphasic osteochondral construct. PLoS One. 2018; 13(4):e0195261. PMID: 29634740.
      View in: PubMed
    6. White JL, Walker NJ, Hu JC, Borjesson DL, Athanasiou KA. A Comparison of Bone Marrow and Cord Blood Mesenchymal Stem Cells for Cartilage Self-Assembly. Tissue Eng Part A. 2018 Apr 02. PMID: 29478385.
      View in: PubMed
    7. Sherlock BE, Harvestine JN, Mitra D, Haudenschild A, Hu J, Athanasiou KA, Leach JK, Marcu L. Nondestructive assessment of collagen hydrogel cross-linking using time-resolved autofluorescence imaging. J Biomed Opt. 2018 Mar; 23(3):1-9. PMID: 29512359.
      View in: PubMed
    8. O'Leary SA, Paschos NK, Link JM, Klineberg EO, Hu JC, Athanasiou KA. Facet Joints of the Spine: Structure-Function Relationships, Problems and Treatments, and the Potential for Regeneration. Annu Rev Biomed Eng. 2018 Mar 01. PMID: 29494214.
      View in: PubMed
    9. Huwe LW, Brown WE, Hu JC, Athanasiou KA. Characterization of costal cartilage and its suitability as a cell source for articular cartilage tissue engineering. J Tissue Eng Regen Med. 2018 May; 12(5):1163-1176. PMID: 29286211.
      View in: PubMed
    10. Lee JK, Link JM, Hu JCY, Athanasiou KA. The Self-Assembling Process and Applications in Tissue Engineering. Cold Spring Harb Perspect Med. 2017 Nov 01; 7(11). PMID: 28348174.
      View in: PubMed
    11. Hadidi P, Cissell DD, Hu JC, Athanasiou KA. Temporal development of near-native functional properties and correlations with qMRI in self-assembling fibrocartilage treated with exogenous lysyl oxidase homolog 2. Acta Biomater. 2017 Dec; 64:29-40. PMID: 28963018.
      View in: PubMed
    12. Huwe LW, Sullan GK, Hu JC, Athanasiou KA. Using Costal Chondrocytes to Engineer Articular Cartilage with Applications of Passive Axial Compression and Bioactive Stimuli. Tissue Eng Part A. 2018 Mar; 24(5-6):516-526. PMID: 28683690.
      View in: PubMed
    13. Kwon H, Haudenschild AK, Brown WE, Vapniarsky N, Paschos NK, Arzi B, Hu JC, Athanasiou KA. Tissue engineering potential of human dermis-isolated adult stem cells from multiple anatomical locations. PLoS One. 2017; 12(8):e0182531. PMID: 28767737.
      View in: PubMed
    14. Vapniarsky N, Aryaei A, Arzi B, Hatcher DC, Hu JC, Athanasiou KA. The Yucatan Minipig Temporomandibular Joint Disc Structure-Function Relationships Support Its Suitability for Human Comparative Studies. Tissue Eng Part C Methods. 2017 Nov; 23(11):700-709. PMID: 28548559.
      View in: PubMed
    15. Lee JK, Huwe LW, Paschos N, Aryaei A, Gegg CA, Hu JC, Athanasiou KA. Tension stimulation drives tissue formation in scaffold-free systems. Nat Mater. 2017 Aug; 16(8):864-873. PMID: 28604717.
      View in: PubMed
    16. Paschos NK, Lim N, Hu JC, Athanasiou KA. Functional properties of native and tissue-engineered cartilage toward understanding the pathogenesis of chondral lesions at the knee: A bovine cadaveric study. J Orthop Res. 2017 11; 35(11):2452-2464. PMID: 28294398.
      View in: PubMed
    17. Cissell DD, Link JM, Hu JC, Athanasiou KA. A Modified Hydroxyproline Assay Based on Hydrochloric Acid in Ehrlich's Solution Accurately Measures Tissue Collagen Content. Tissue Eng Part C Methods. 2017 04; 23(4):243-250. PMID: 28406755.
      View in: PubMed
    18. O'Leary SA, Link JM, Klineberg EO, Hu JC, Athanasiou KA. Characterization of facet joint cartilage properties in the human and interspecies comparisons. Acta Biomater. 2017 05; 54:367-376. PMID: 28300721.
      View in: PubMed
    19. Aryaei A, Vapniarsky N, Hu JC, Athanasiou KA. Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders. Curr Osteoporos Rep. 2016 Dec; 14(6):269-279. PMID: 27704395.
      View in: PubMed
    20. Brown WE, Hu JC, Athanasiou KA. Ammonium-Chloride-Potassium Lysing Buffer Treatment of Fully Differentiated Cells Increases Cell Purity and Resulting Neotissue Functional Properties. Tissue Eng Part C Methods. 2016 09; 22(9):895-903. PMID: 27553086.
      View in: PubMed
    21. Huang BJ, Hu JC, Athanasiou KA. Effects of passage number and post-expansion aggregate culture on tissue engineered, self-assembled neocartilage. Acta Biomater. 2016 10 01; 43:150-159. PMID: 27475530; PMCID: PMC5012947 [Available on 10/01/17].
    22. Huang BJ, Huey DJ, Hu JC, Athanasiou KA. Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell-seeding density and dexamethasone concentration. J Tissue Eng Regen Med. 2017 Aug; 11(8):2323-2332. PMID: 27138113.
      View in: PubMed
    23. Huang BJ, Hu JC, Athanasiou KA. Cell-based tissue engineering strategies used in the clinical repair of articular cartilage. Biomaterials. 2016 08; 98:1-22. PMID: 27177218; PMCID: PMC4899115 [Available on 08/01/17].
    24. Lee JK, Hu JC, Yamada S, Athanasiou KA. Initiation of Chondrocyte Self-Assembly Requires an Intact Cytoskeletal Network. Tissue Eng Part A. 2016 Feb; 22(3-4):318-25. PMID: 26729374; PMCID: PMC4779322 [Available on 02/01/17].
    25. Kwon H, Paschos NK, Hu JC, Athanasiou K. Articular cartilage tissue engineering: the role of signaling molecules. Cell Mol Life Sci. 2016 Mar; 73(6):1173-94. PMID: 26811234.
      View in: PubMed
    26. Peng G, McNary SM, Athanasiou KA, Reddi AH. Superficial Zone Extracellular Matrix Extracts Enhance Boundary Lubrication of Self-Assembled Articular Cartilage. Cartilage. 2016 Jul; 7(3):256-64. PMID: 27375841; PMCID: PMC4918063 [Available on 01/01/17].
    27. Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson DL. Companion animals: Translational scientist's new best friends. Sci Transl Med. 2015 Oct 07; 7(308):308ps21. PMID: 26446953; PMCID: PMC4806851 [Available on 10/07/16].
    28. Vapniarsky N, Arzi B, Hu JC, Nolta JA, Athanasiou KA. Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine. Stem Cells Transl Med. 2015 Oct; 4(10):1187-98. PMID: 26253713; PMCID: PMC4572907 [Available on 10/01/16].
    29. Murphy MK, Huey DJ, Hu JC, Athanasiou KA. TGF-ß1, GDF-5, and BMP-2 stimulation induces chondrogenesis in expanded human articular chondrocytes and marrow-derived stromal cells. Stem Cells. 2015 Mar; 33(3):762-73. PMID: 25377511.
      View in: PubMed
    30. Moran CJ, Busilacchi A, Lee CA, Athanasiou KA, Verdonk PC. Biological augmentation and tissue engineering approaches in meniscus surgery. Arthroscopy. 2015 May; 31(5):944-55. PMID: 25687715.
      View in: PubMed
    31. Lee JK, Gegg CA, Hu JC, Reddi AH, Athanasiou KA. Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage. Arthritis Res Ther. 2015 Feb 11; 17:28. PMID: 25884593; PMCID: PMC4355350.
    32. Murphy MK, Arzi B, Prouty SM, Hu JC, Athanasiou KA. Neocartilage integration in temporomandibular joint discs: physical and enzymatic methods. J R Soc Interface. 2015 Feb 06; 12(103). PMID: 25519993; PMCID: PMC4305410.
    33. Athanasiou KA, Responte DJ, Brown WE, Hu JC. Harnessing biomechanics to develop cartilage regeneration strategies. J Biomech Eng. 2015 Feb 01; 137(2):020901. PMID: 25322349; PMCID: PMC4321108.
    34. Makris EA, Huang BJ, Hu JC, Chen-Izu Y, Athanasiou KA. Digoxin and adenosine triphosphate enhance the functional properties of tissue-engineered cartilage. Tissue Eng Part A. 2015 Mar; 21(5-6):884-94. PMID: 25473799; PMCID: PMC4356188.
    35. MacBarb RF, Paschos NK, Abeug R, Makris EA, Hu JC, Athanasiou KA. Passive strain-induced matrix synthesis and organization in shape-specific, cartilaginous neotissues. Tissue Eng Part A. 2014 Dec; 20(23-24):3290-302. PMID: 24918268; PMCID: PMC4259198.
    36. Makris EA, Responte DJ, Paschos NK, Hu JC, Athanasiou KA. Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase-induced collagen cross-linking. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):E4832-41. PMID: 25349395; PMCID: PMC4234579.
    37. DuRaine GD, Brown WE, Hu JC, Athanasiou KA. Emergence of scaffold-free approaches for tissue engineering musculoskeletal cartilages. Ann Biomed Eng. 2015 Mar; 43(3):543-54. PMID: 25331099; PMCID: PMC4380596.
    38. Lee JK, Gegg CA, Hu JC, Kass PH, Athanasiou KA. Promoting increased mechanical properties of tissue engineered neocartilage via the application of hyperosmolarity and 4a-phorbol 12,13-didecanoate (4aPDD). J Biomech. 2014 Nov 28; 47(15):3712-8. PMID: 25442009.
      View in: PubMed
    39. Makris EA, Gomoll AH, Malizos KN, Hu JC, Athanasiou KA. Repair and tissue engineering techniques for articular cartilage. Nat Rev Rheumatol. 2015 Jan; 11(1):21-34. PMID: 25247412; PMCID: PMC4629810.
    40. Hadidi P, Yeh TC, Hu JC, Athanasiou KA. Critical seeding density improves the properties and translatability of self-assembling anatomically shaped knee menisci. Acta Biomater. 2015 Jan; 11:173-82. PMID: 25234157; PMCID: PMC4278572.
    41. Paschos NK, Makris EA, Hu JC, Athanasiou KA. Topographic variations in biomechanical and biochemical properties in the ankle joint: an in vitro bovine study evaluating native and engineered cartilage. Arthroscopy. 2014 Oct; 30(10):1317-26. PMID: 25064757.
      View in: PubMed
    42. Kalpakci KN, Brown WE, Hu JC, Athanasiou KA. Cartilage tissue engineering using dermis isolated adult stem cells: the use of hypoxia during expansion versus chondrogenic differentiation. PLoS One. 2014; 9(5):e98570. PMID: 24867063; PMCID: PMC4035316.
    43. Makris EA, MacBarb RF, Paschos NK, Hu JC, Athanasiou KA. Combined use of chondroitinase-ABC, TGF-ß1, and collagen crosslinking agent lysyl oxidase to engineer functional neotissues for fibrocartilage repair. Biomaterials. 2014 Aug; 35(25):6787-96. PMID: 24840619; PMCID: PMC4105108.
    44. Paschos NK, Brown WE, Eswaramoorthy R, Hu JC, Athanasiou KA. Advances in tissue engineering through stem cell-based co-culture. J Tissue Eng Regen Med. 2015 May; 9(5):488-503. PMID: 24493315.
      View in: PubMed
    45. Murphy MK, Masters TE, Hu JC, Athanasiou KA. Engineering a fibrocartilage spectrum through modulation of aggregate redifferentiation. Cell Transplant. 2015; 24(2):235-45. PMID: 24380383; PMCID: PMC4331269.
    46. Cissell DD, Hu JC, Griffiths LG, Athanasiou KA. Antigen removal for the production of biomechanically functional, xenogeneic tissue grafts. J Biomech. 2014 Jun 27; 47(9):1987-96. PMID: 24268315; PMCID: PMC4014533.
    47. Higashioka MM, Chen JA, Hu JC, Athanasiou KA. Building an anisotropic meniscus with zonal variations. Tissue Eng Part A. 2014 Jan; 20(1-2):294-302. PMID: 23931258; PMCID: PMC3875205.
    48. Lee JK, Responte DJ, Cissell DD, Hu JC, Nolta JA, Athanasiou KA. Clinical translation of stem cells: insight for cartilage therapies. Crit Rev Biotechnol. 2014 Mar; 34(1):89-100. PMID: 24083452; PMCID: PMC4314285.
    49. MacBarb RF, Chen AL, Hu JC, Athanasiou KA. Engineering functional anisotropy in fibrocartilage neotissues. Biomaterials. 2013 Dec; 34(38):9980-9. PMID: 24075479; PMCID: PMC3885350.
    50. Athanasiou KA, Eswaramoorthy R, Hadidi P, Hu JC. Self-organization and the self-assembling process in tissue engineering. Annu Rev Biomed Eng. 2013; 15:115-36. PMID: 23701238; PMCID: PMC4420200.
    51. Makris EA, MacBarb RF, Responte DJ, Hu JC, Athanasiou KA. A copper sulfate and hydroxylysine treatment regimen for enhancing collagen cross-linking and biomechanical properties in engineered neocartilage. FASEB J. 2013 Jun; 27(6):2421-30. PMID: 23457219; PMCID: PMC3659348.
    52. Hadidi P, Athanasiou KA. Enhancing the mechanical properties of engineered tissue through matrix remodeling via the signaling phospholipid lysophosphatidic acid. Biochem Biophys Res Commun. 2013 Mar 29; 433(1):133-8. PMID: 23458458; PMCID: PMC3626273.
    53. Murphy MK, Huey DJ, Reimer AJ, Hu JC, Athanasiou KA. Enhancing post-expansion chondrogenic potential of costochondral cells in self-assembled neocartilage. PLoS One. 2013; 8(2):e56983. PMID: 23437288; PMCID: PMC3578801.
    54. Huey DJ, Athanasiou KA. Alteration of the fibrocartilaginous nature of scaffoldless constructs formed from leporine meniscus cells and chondrocytes through manipulation of culture and processing conditions. Cells Tissues Organs. 2013; 197(5):360-71. PMID: 23406714; PMCID: PMC3718672.
    55. Wong ML, Wong JL, Athanasiou KA, Griffiths LG. Stepwise solubilization-based antigen removal for xenogeneic scaffold generation in tissue engineering. Acta Biomater. 2013 May; 9(5):6492-501. PMID: 23321301.
      View in: PubMed
    56. Arzi B, Cissell DD, Verstraete FJ, Kass PH, DuRaine GD, Athanasiou KA. Computed tomographic findings in dogs and cats with temporomandibular joint disorders: 58 cases (2006-2011). J Am Vet Med Assoc. 2013 Jan 01; 242(1):69-75. PMID: 23234284; PMCID: PMC3747040.
    57. Murphy MK, DuRaine GD, Reddi A, Hu JC, Athanasiou KA. Inducing articular cartilage phenotype in costochondral cells. Arthritis Res Ther. 2013; 15(6):R214. PMID: 24330640; PMCID: PMC3979093.
    58. Huey DJ, Hu JC, Athanasiou KA. Unlike bone, cartilage regeneration remains elusive. Science. 2012 Nov 16; 338(6109):917-21. PMID: 23161992; PMCID: PMC4327988.
    59. Eleswarapu SV, Athanasiou KA. TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs. Acta Biomater. 2013 Mar; 9(3):5554-61. PMID: 23128162; PMCID: PMC3562419.
    60. MacBarb RF, Makris EA, Hu JC, Athanasiou KA. A chondroitinase-ABC and TGF-ß1 treatment regimen for enhancing the mechanical properties of tissue-engineered fibrocartilage. Acta Biomater. 2013 Jan; 9(1):4626-34. PMID: 23041782; PMCID: PMC3518537.
    61. Huey DJ, Hu JC, Athanasiou KA. Chondrogenically tuned expansion enhances the cartilaginous matrix-forming capabilities of primary, adult, leporine chondrocytes. Cell Transplant. 2013; 22(2):331-40. PMID: 23044188; PMCID: PMC3581742.
    62. Responte DJ, Lee JK, Hu JC, Athanasiou KA. Biomechanics-driven chondrogenesis: from embryo to adult. FASEB J. 2012 Sep; 26(9):3614-24. PMID: 22673579; PMCID: PMC3425829.
    63. Responte DJ, Arzi B, Natoli RM, Hu JC, Athanasiou KA. Mechanisms underlying the synergistic enhancement of self-assembled neocartilage treated with chondroitinase-ABC and TGF-ß1. Biomaterials. 2012 Apr; 33(11):3187-94. PMID: 22284584; PMCID: PMC3275670.
    64. Sun Y, Responte D, Xie H, Liu J, Fatakdawala H, Hu J, Athanasiou KA, Marcu L. Nondestructive evaluation of tissue engineered articular cartilage using time-resolved fluorescence spectroscopy and ultrasound backscatter microscopy. Tissue Eng Part C Methods. 2012 Mar; 18(3):215-26. PMID: 22010819; PMCID: PMC3285603.
    65. Arzi B, Wisner ER, Huey DJ, Kass PH, Hu J, Athanasiou KA. A proposed model of naturally occurring osteoarthritis in the domestic rabbit. Lab Anim (NY). 2011 Dec 19; 41(1):20-5. PMID: 22184086; PMCID: PMC4326101.
    66. Huey DJ, Athanasiou KA. Tension-compression loading with chemical stimulation results in additive increases to functional properties of anatomic meniscal constructs. PLoS One. 2011; 6(11):e27857. PMID: 22114714; PMCID: PMC3218070.
    67. Eleswarapu SV, Chen JA, Athanasiou KA. Temporal assessment of ribose treatment on self-assembled articular cartilage constructs. Biochem Biophys Res Commun. 2011 Oct 22; 414(2):431-6. PMID: 21971556; PMCID: PMC3200502.
    68. Sanchez-Adams J, Willard VP, Athanasiou KA. Regional variation in the mechanical role of knee meniscus glycosaminoglycans. J Appl Physiol (1985). 2011 Dec; 111(6):1590-6. PMID: 21903884; PMCID: PMC3233877.
    69. Bhatavadekar NB, Hu J, Keys K, Ofek G, Athanasiou KA. Novel application of cytodetachment technology to the analysis of dental implant surfaces. Int J Oral Maxillofac Implants. 2011 Sep-Oct; 26(5):985-90. PMID: 22010080.
      View in: PubMed
    70. Wong ML, Leach JK, Athanasiou KA, Griffiths LG. The role of protein solubilization in antigen removal from xenogeneic tissue for heart valve tissue engineering. Biomaterials. 2011 Nov; 32(32):8129-38. PMID: 21810537.
      View in: PubMed
    71. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials. 2011 Oct; 32(30):7411-31. PMID: 21764438; PMCID: PMC3161498.
    72. Athanasiou KA. Special issues. Ann Biomed Eng. 2011 Jun; 39(6):1607. PMID: 21547589.
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    73. Huey DJ, Athanasiou KA. Maturational growth of self-assembled, functional menisci as a result of TGF-ß1 and enzymatic chondroitinase-ABC stimulation. Biomaterials. 2011 Mar; 32(8):2052-8. PMID: 21145584; PMCID: PMC3038547.
    74. Natoli RM, Skaalure S, Bijlani S, Chen KX, Hu J, Athanasiou KA. Intracellular Na(+) and Ca(2+) modulation increases the tensile properties of developing engineered articular cartilage. Arthritis Rheum. 2010 Apr; 62(4):1097-107. PMID: 20131245; PMCID: PMC2909188.
    75. Feng Y, Ofek G, Choi DS, Wen J, Hu J, Zhao H, Zu Y, Athanasiou KA, Chang CC. Unique biomechanical interactions between myeloma cells and bone marrow stroma cells. Prog Biophys Mol Biol. 2010 Sep; 103(1):148-56. PMID: 19840813.
      View in: PubMed
    76. Ofek G, Willard VP, Koay EJ, Hu JC, Lin P, Athanasiou KA. Mechanical characterization of differentiated human embryonic stem cells. J Biomech Eng. 2009 Jun; 131(6):061011. PMID: 19449965; PMCID: PMC2817935.
    77. Zhang L, Hu J, Athanasiou KA. The role of tissue engineering in articular cartilage repair and regeneration. Crit Rev Biomed Eng. 2009; 37(1-2):1-57. PMID: 20201770; PMCID: PMC3146065.
    78. Anderson DE, Athanasiou KA. Passaged goat costal chondrocytes provide a feasible cell source for temporomandibular joint tissue engineering. Ann Biomed Eng. 2008 Dec; 36(12):1992-2001. PMID: 18830818; PMCID: PMC2909190.
    79. Ofek G, Revell CM, Hu JC, Allison DD, Grande-Allen KJ, Athanasiou KA. Matrix development in self-assembly of articular cartilage. PLoS One. 2008 Jul 30; 3(7):e2795. PMID: 18665220; PMCID: PMC2464773.
    80. Revell CM, Reynolds CE, Athanasiou KA. Effects of initial cell seeding in self assembly of articular cartilage. Ann Biomed Eng. 2008 Sep; 36(9):1441-8. PMID: 18574692; PMCID: PMC3164522.
    81. Natoli RM, Scott CC, Athanasiou KA. Temporal effects of impact on articular cartilage cell death, gene expression, matrix biochemistry, and biomechanics. Ann Biomed Eng. 2008 May; 36(5):780-92. PMID: 18299988.
      View in: PubMed
    82. Hoben GM, Hu JC, James RA, Athanasiou KA. Self-assembly of fibrochondrocytes and chondrocytes for tissue engineering of the knee meniscus. Tissue Eng. 2007 May; 13(5):939-46. PMID: 17484700.
      View in: PubMed
    83. Detamore MS, Athanasiou KA, Mao J. A call to action for bioengineers and dental professionals: directives for the future of TMJ bioengineering. Ann Biomed Eng. 2007 Aug; 35(8):1301-11. PMID: 17393335.
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    84. Deng Y, Hu JC, Athanasiou KA. Isolation and chondroinduction of a dermis-isolated, aggrecan-sensitive subpopulation with high chondrogenic potential. Arthritis Rheum. 2007 Jan; 56(1):168-76. PMID: 17195219.
      View in: PubMed
    85. Aufderheide AC, Athanasiou KA. A direct compression stimulator for articular cartilage and meniscal explants. Ann Biomed Eng. 2006 Sep; 34(9):1463-74. PMID: 16897420.
      View in: PubMed
    86. Hu JC, Athanasiou KA. The effects of intermittent hydrostatic pressure on self-assembled articular cartilage constructs. Tissue Eng. 2006 May; 12(5):1337-44. PMID: 16771646.
      View in: PubMed
    87. Hu JC, Athanasiou KA. A self-assembling process in articular cartilage tissue engineering. Tissue Eng. 2006 Apr; 12(4):969-79. PMID: 16674308.
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    88. Hu JC, Athanasiou KA. Chondrocytes from different zones exhibit characteristic differences in high density culture. Connect Tissue Res. 2006; 47(3):133-40. PMID: 16753806.
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    89. Almarza AJ, Athanasiou KA. Effects of initial cell seeding density for the tissue engineering of the temporomandibular joint disc. Ann Biomed Eng. 2005 Jul; 33(7):943-50. PMID: 16060535.
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    90. Allen KD, Athanasiou KA. A surface-regional and freeze-thaw characterization of the porcine temporomandibular joint disc. Ann Biomed Eng. 2005 Jul; 33(7):951-62. PMID: 16060536.
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    91. Hu JC, Athanasiou KA. Low-density cultures of bovine chondrocytes: effects of scaffold material and culture system. Biomaterials. 2005 May; 26(14):2001-12. PMID: 15576174.
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    92. Detamore MS, Athanasiou KA. Evaluation of three growth factors for TMJ disc tissue engineering. Ann Biomed Eng. 2005 Mar; 33(3):383-90. PMID: 15868729; PMCID: PMC4474384.
    93. Darling EM, Hu JC, Athanasiou KA. Zonal and topographical differences in articular cartilage gene expression. J Orthop Res. 2004 Nov; 22(6):1182-7. PMID: 15475195.
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    94. AufderHeide AC, Athanasiou KA. Mechanical stimulation toward tissue engineering of the knee meniscus. Ann Biomed Eng. 2004 Aug; 32(8):1161-74. PMID: 15446512.
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    95. Niederauer GG, Niederauer GM, Cullen LC, Athanasiou KA, Thomas JB, Niederauer MQ. Correlation of cartilage stiffness to thickness and level of degeneration using a handheld indentation probe. Ann Biomed Eng. 2004 Mar; 32(3):352-9. PMID: 15095809.
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    96. Almarza AJ, Athanasiou KA. Design characteristics for the tissue engineering of cartilaginous tissues. Ann Biomed Eng. 2004 Jan; 32(1):2-17. PMID: 14964717.
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    97. Darling EM, Athanasiou KA. Biomechanical strategies for articular cartilage regeneration. Ann Biomed Eng. 2003 Oct; 31(9):1114-24. PMID: 14582614.
      View in: PubMed
    98. Kim KW, Wong ME, Helfrick JF, Thomas JB, Athanasiou KA. Biomechanical tissue characterization of the superior joint space of the porcine temporomandibular joint. Ann Biomed Eng. 2003 Sep; 31(8):924-30. PMID: 12918907.
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    99. Shieh AC, Athanasiou KA. Principles of cell mechanics for cartilage tissue engineering. Ann Biomed Eng. 2003 Jan; 31(1):1-11. PMID: 12572651.
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