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Mark A Zern

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InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chen J, Tschudy-Seney B, Ma X, Zern M, Liu P, Duan Y. Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway. Stem Cells Dev. 2018 Feb 15; 27(4):252-261. PMID: 29256825.
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    2. Chen J, Chen L, Zern M, Theise ND, Diehl AM, Liu P, Duan Y. The diversity and plasticity of adult hepatic progenitor cells and their niche. Liver Int. 2017 Sep; 37(9):1260-1271. PMID: 28135758.
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    3. Chen J, Gao W, Zhou P, Ma X, Tschudy-Seney B, Liu C, Zern M, Liu P, Duan Y. Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu. Sci Rep. 2016 Jan 06; 6:18841. PMID: 26733102; PMCID: PMC4702137.
    4. Zhang X, Du G, Xu Y, Li X, Fan W, Chen J, Liu C, Chen G, Liu C, Zern M, Mu Y, Liu P. Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes. Lab Invest. 2016 Mar; 96(3):350-60. PMID: 26692291.
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    5. Zeng C, Zhang Y, Park SC, Eun JR, Nguyen NT, Tschudy-Seney B, Jung YJ, Theise ND, Zern M, Duan Y. CD34(+) Liver Cancer Stem Cells Were Formed by Fusion of Hepatobiliary Stem/Progenitor Cells with Hematopoietic Precursor-Derived Myeloid Intermediates. Stem Cells Dev. 2015 Nov 01; 24(21):2467-78. PMID: 26192559; PMCID: PMC4620524 [Available on 11/01/16].
    6. Chen J, Zhang X, Xu Y, Li X, Ren S, Zhou Y, Duan Y, Zern M, Zhang H, Chen G, Liu C, Mu Y, Liu P. Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway. PLoS One. 2015; 10(6):e0130310. PMID: 26087010; PMCID: PMC4473299.
    7. Park SC, Zeng C, Tschudy-Seney B, Nguyen NT, Eun JR, Zhang Y, Ramsamooj R, Zhang Y, Zhao M, Theise ND, Zhou H, Zern M, Duan Y. Clonogenically Culturing and Expanding CD34+ Liver Cancer Stem Cells in Vitro. Stem Cells Dev. 2015 Jul 01; 24(13):1506-14. PMID: 25867583; PMCID: PMC4499771.
    8. Fan YH, Ding J, Nguyen S, Liu XJ, Xu G, Zhou HY, Duan NN, Yang SM, Zern M, Wu J. Aberrant hedgehog signaling is responsible for the highly invasive behavior of a subpopulation of hepatoma cells. Oncogene. 2016 Jan 07; 35(1):116-24. PMID: 25772244.
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    9. Park SC, Nguyen NT, Eun JR, Zhang Y, Jung YJ, Tschudy-Seney B, Trotsyuk A, Lam A, Ramsamooj R, Zhang Y, Theise ND, Zern M, Duan Y. Identification of cancer stem cell subpopulations of CD34(+) PLC/PRF/5 that result in three types of human liver carcinomas. Stem Cells Dev. 2015 Apr 15; 24(8):1008-21. PMID: 25519836; PMCID: PMC4390116.
    10. Gao W, Zhou P, Ma X, Tschudy-Seney B, Chen J, Magner NL, Revzin A, Nolta JA, Zern M, Duan Y. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro. PLoS One. 2014; 9(11):e112698. PMID: 25393427; PMCID: PMC4231066.
    11. Eun JR, Jung YJ, Zhang Y, Zhang Y, Tschudy-Seney B, Ramsamooj R, Wan YJ, Theise ND, Zern M, Duan Y. Hepatoma SK Hep-1 cells exhibit characteristics of oncogenic mesenchymal stem cells with highly metastatic capacity. PLoS One. 2014; 9(10):e110744. PMID: 25338121; PMCID: PMC4206444.
    12. Magner NL, Jung Y, Wu J, Nolta JA, Zern M, Zhou P. Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway. Stem Cells. 2013 Oct; 31(10):2095-103. PMID: 23836547.
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    13. Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern M. Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Transl Med. 2013 Jun; 2(6):409-19. PMID: 23681950; PMCID: PMC3673753.
    14. Ghaedi M, Duan Y, Zern M, Revzin A. Hepatic differentiation of human embryonic stem cells on growth factor-containing surfaces. J Tissue Eng Regen Med. 2014 Nov; 8(11):886-95. PMID: 23086797.
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    15. Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, de vere White RW, Farnham PJ, Zern M. Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFß tumor suppressor signaling pathways. Mol Cancer Res. 2012 Jul; 10(7):979-91. PMID: 22622027; PMCID: PMC4166560.
    16. Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M. Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One. 2011; 6(11):e27740. PMID: 22140464; PMCID: PMC3225380.
    17. Behbahan IS, Duan Y, Lam A, Khoobyari S, Ma X, Ahuja TP, Zern M. New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem Cell Rev. 2011 Sep; 7(3):748-59. PMID: 21336836; PMCID: PMC3137783.
    18. Zhou P, Lessa N, Estrada DC, Severson EB, Lingala S, Zern M, Nolta JA, Wu J. Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice. Liver Transpl. 2011 Apr; 17(4):418-27. PMID: 21445925; PMCID: PMC3079538.
    19. Ghaedi M, Tuleuova N, Zern M, Wu J, Revzin A. Bottom-up signaling from HGF-containing surfaces promotes hepatic differentiation of mesenchymal stem cells. Biochem Biophys Res Commun. 2011 Apr 08; 407(2):295-300. PMID: 21382341; PMCID: PMC3075384.
    20. Chen X, Lingala S, Khoobyari S, Nolta J, Zern M, Wu J. Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. J Hepatol. 2011 Oct; 55(4):838-45. PMID: 21334406; PMCID: PMC3177032.
    21. Schie IW, Wu J, Weeks T, Zern M, Rutledge JC, Huser T. Label-free imaging and analysis of the effects of lipolysis products on primary hepatocytes. J Biophotonics. 2011 Jun; 4(6):425-34. PMID: 20878906; PMCID: PMC3696389.
    22. Tuleuova N, Lee JY, Lee J, Ramanculov E, Zern M, Revzin A. Using growth factor arrays and micropatterned co-cultures to induce hepatic differentiation of embryonic stem cells. Biomaterials. 2010 Dec; 31(35):9221-31. PMID: 20832855; PMCID: PMC2956853.
    23. Salama H, Zekri AR, Zern M, Bahnassy A, Loutfy S, Shalaby S, Vigen C, Burke W, Mostafa M, Medhat E, Alfi O, Huttinger E. Autologous hematopoietic stem cell transplantation in 48 patients with end-stage chronic liver diseases. Cell Transplant. 2010; 19(11):1475-86. PMID: 20587151.
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    24. Jones CN, Tuleuova N, Lee JY, Ramanculov E, Reddi AH, Zern M, Revzin A. Cultivating hepatocytes on printed arrays of HGF and BMP7 to characterize protective effects of these growth factors during in vitro alcohol injury. Biomaterials. 2010 Aug; 31(23):5936-44. PMID: 20488537; PMCID: PMC2893270.
    25. Lingala S, Cui YY, Chen X, Ruebner BH, Qian XF, Zern M, Wu J. Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma. Exp Mol Pathol. 2010 Aug; 89(1):27-35. PMID: 20511115; PMCID: PMC2900434.
    26. Duan Y, Ma X, Ma X, Zou W, Wang C, Bahbahan IS, Ahuja TP, Tolstikov V, Zern M. Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. Stem Cells. 2010 Apr; 28(4):674-86. PMID: 20135682.
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    27. Yoon S, Kim TH, Natarajan A, Wang SS, Choi J, Wu J, Zern M, Venugopal SK. Acute liver injury upregulates microRNA-491-5p in mice, and its overexpression sensitizes Hep G2 cells for tumour necrosis factor-alpha-induced apoptosis. Liver Int. 2010 Mar; 30(3):376-87. PMID: 20015148.
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    28. Venugopal SK, Jiang J, Kim TH, Li Y, Wang SS, Torok NJ, Wu J, Zern M. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G101-6. PMID: 19892940; PMCID: PMC2806096.
    29. Lee JY, Tuleuova N, Jones CN, Ramanculov E, Zern M, Revzin A. Directing hepatic differentiation of embryonic stem cells with protein microarray-based co-cultures. Integr Biol (Camb). 2009 Jul; 1(7):460-8. PMID: 20023756.
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    30. Jones CN, Tuleuova N, Lee JY, Ramanculov E, Reddi AH, Zern M, Revzin A. Cultivating liver cells on printed arrays of hepatocyte growth factor. Biomaterials. 2009 Aug; 30(22):3733-41. PMID: 19375794.
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    31. Zern M. Cell transplantation to replace whole liver transplantation. Gastroenterology. 2009 Mar; 136(3):767-9. PMID: 19167399.
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    32. Tatsukawa H, Fukaya Y, Frampton G, Martinez-Fuentes A, Suzuki K, Kuo TF, Nagatsuma K, Shimokado K, Okuno M, Wu J, Iismaa S, Matsuura T, Tsukamoto H, Zern M, Graham RM, Kojima S. Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1. Gastroenterology. 2009 May; 136(5):1783-95.e10. PMID: 19208340; PMCID: PMC4960455.
    33. Kim TH, Venugopal SK, Zhu M, Wang SS, Lau D, Lam KS, Clemens DL, Zern M. A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells. Biochem Biophys Res Commun. 2009 Feb 20; 379(4):876-81. PMID: 19133235.
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    34. Ma X, Duan Y, Jung CJ, Wu J, VandeVoort CA, Zern M. The differentiation of hepatocyte-like cells from monkey embryonic stem cells. Cloning Stem Cells. 2008 Dec; 10(4):485-93. PMID: 18795869; PMCID: PMC2981381.
    35. Jones CN, Lee JY, Zhu J, Stybayeva G, Ramanculov E, Zern M, Revzin A. Multifunctional protein microarrays for cultivation of cells and immunodetection of secreted cellular products. Anal Chem. 2008 Aug 15; 80(16):6351-7. PMID: 18642875.
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    36. Choi MS, Catana AM, Wu J, Kim YS, Yoon SJ, Borowsky AD, Gambhir SS, Gupta S, Zern M. Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice. Cell Transplant. 2008; 17(8):899-909. PMID: 19069633.
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    37. Venugopal SK, Wu J, Catana AM, Eisenbud L, He SQ, Duan YY, Follenzi A, Zern M. Lentivirus-mediated superoxide dismutase1 gene delivery protects against oxidative stress-induced liver injury in mice. Liver Int. 2007 Dec; 27(10):1311-22. PMID: 18036097.
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    38. Duan Y, Catana A, Meng Y, Yamamoto N, He S, Gupta S, Gambhir SS, Zern M. Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo. Stem Cells. 2007 Dec; 25(12):3058-68. PMID: 17885076.
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    39. Venugopal SK, Chen J, Zhang Y, Clemens D, Follenzi A, Zern M. Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells. J Biol Chem. 2007 Nov 02; 282(44):31900-8. PMID: 17848570.
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    40. Zhang Y, Venugopal SK, He S, Liu P, Wu J, Zern M. Ethanol induces apoptosis in hepatocytes by a pathway involving novel protein kinase C isoforms. Cell Signal. 2007 Nov; 19(11):2339-50. PMID: 17728104.
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    41. Seo S, Maganti K, Khehra M, Ramsamooj R, Tsodikov A, Bowlus C, McVicar J, Zern M, Torok N. De novo nonalcoholic fatty liver disease after liver transplantation. Liver Transpl. 2007 Jun; 13(6):844-7. PMID: 17029282.
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    42. Kim JW, Zhang YH, Zern M, Rossi JJ, Wu J. Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. Biochem Biophys Res Commun. 2007 Jul 27; 359(2):292-7. PMID: 17533113; PMCID: PMC2474738.
    43. Lee JY, Jones C, Zern M, Revzin A. Analysis of local tissue-specific gene expression in cellular micropatterns. Anal Chem. 2006 Dec 15; 78(24):8305-12. PMID: 17165820.
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    44. He SQ, Zhang YH, Venugopal SK, Dicus CW, Perez RV, Ramsamooj R, Nantz MH, Zern M, Wu J. Delivery of antioxidative enzyme genes protects against ischemia/reperfusion-induced liver injury in mice. Liver Transpl. 2006 Dec; 12(12):1869-79. PMID: 17133584.
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    45. Yamamoto N, Wu J, Zhang Y, Catana AM, Cai H, Strom S, Novikoff PM, Zern M. An optimal culture condition maintains human hepatocyte phenotype after long-term culture. Hepatol Res. 2006 Jul; 35(3):169-77. PMID: 16807086.
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    46. Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern M, Torok NJ. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology. 2006 Mar; 43(3):435-43. PMID: 16496318.
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    47. Bowlus CL, Willner I, Zern M, Reuben A, Chen P, Holladay B, Xie L, Woolson RF, Strange C. Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency. Clin Gastroenterol Hepatol. 2005 Apr; 3(4):390-6. PMID: 15822045.
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    48. Duan YY, Wu J, Zhu JL, Liu SL, Ozaki I, Strayer DS, Zern M. Gene therapy for human alpha1-antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology. 2004 Oct; 127(4):1222-32. PMID: 15480999.
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    49. Wu J, Liu L, Yen RD, Catana A, Nantz MH, Zern M. Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology. 2004 Jul; 40(1):195-204. PMID: 15239103.
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    50. Wu J, Zern M. Tissue transglutaminase, a key enzyme involved in liver diseases. Hepatol Res. 2004 May; 29(1):1-8. PMID: 15135339.
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    51. Shirahashi H, Wu J, Yamamoto N, Catana A, Wege H, Wager B, Okita K, Zern M. Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage. Cell Transplant. 2004; 13(3):197-211. PMID: 15191158.
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    52. Zalzman M, Gupta S, Giri RK, Berkovich I, Sappal BS, Karnieli O, Zern M, Fleischer N, Efrat S. Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):7253-8. PMID: 12756298; PMCID: PMC165862.
    53. Cordelier P, Zern M, Strayer DS. HIV-1 proprotein processing as a target for gene therapy. Gene Ther. 2003 Mar; 10(6):467-77. PMID: 12621451.
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    54. Wege H, Le HT, Chui MS, Liu L, Wu J, Giri R, Malhi H, Sappal BS, Kumaran V, Gupta S, Zern M. Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology. 2003 Feb; 124(2):432-44. PMID: 12557149.
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    55. Wege H, Chui MS, Le HT, Tran JM, Zern M. SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. Nucleic Acids Res. 2003 Jan 15; 31(2):E3-3. PMID: 12527792; PMCID: PMC140528.
    56. Wege H, Chui MS, Le HT, Strom SC, Zern M. In vitro expansion of human hepatocytes is restricted by telomere-dependent replicative aging. Cell Transplant. 2003; 12(8):897-906. PMID: 14763510.
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    57. Liu L, Zern M, Lizarzaburu ME, Nantz MH, Wu J. Poly(cationic lipid)-mediated in vivo gene delivery to mouse liver. Gene Ther. 2003 Jan; 10(2):180-7. PMID: 12571647.
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    58. Strayer DS, Zern M, Chowdhury JR. What can SV40-derived vectors do for gene therapy? Curr Opin Mol Ther. 2002 Aug; 4(4):313-23. PMID: 12222869.
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    59. Strayer D, Branco F, Zern M, Yam P, Calarota SA, Nichols CN, Zaia JA, Rossi J, Li H, Parashar B, Ghosh S, Chowdhury JR. Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Mol Ther. 2002 Aug; 6(2):227-37. PMID: 12161189.
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    60. Wu J, Nantz MH, Zern M. Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applications. Front Biosci. 2002 Mar 01; 7:d717-25. PMID: 11861224.
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    61. Wu J, Lizarzaburu ME, Kurth MJ, Liu L, Wege H, Zern M, Nantz MH. Cationic lipid polymerization as a novel approach for constructing new DNA delivery agents. Bioconjug Chem. 2001 Mar-Apr; 12(2):251-7. PMID: 11312686.
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    62. Di Campli C, Nocente R, Costamagna G, Gentiloni N, Burioni R, Wu J, Armuzzi A, Zern M, Gasbarrini G, Gasbarrini A. No evidence of Helicobacter pylori sequences in pancreatic juices of patients affected by chronic pancreatitis. Int J Pancreatol. 2000 Dec; 28(3):181-5. PMID: 11373055.
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    63. Wu J, Liu SL, Zhu JL, Norton PA, Nojiri S, Hoek JB, Zern M. Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction. J Biol Chem. 2000 Jul 21; 275(29):22213-9. PMID: 10801782.
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    64. Wu J, Zern M. Hepatic stellate cells: a target for the treatment of liver fibrosis. J Gastroenterol. 2000; 35(9):665-72. PMID: 11023037.
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    65. Zhu J, Wu J, Frizell E, Liu SL, Bashey R, Rubin R, Norton P, Zern M. Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology. 1999 Nov; 117(5):1198-204. PMID: 10535884.
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    66. Ozaki I, Zern M. [Recent progress of pathogenesis and treatment in alpha 1-antitrypsin deficiency]. Nihon Rinsho. 1999 Sep; 57(9):2145-51. PMID: 10497421.
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    67. Ozaki I, Zern M, Liu S, Wei DL, Pomerantz RJ, Duan L. Ribozyme-mediated specific gene replacement of the alpha1-antitrypsin gene in human hepatoma cells. J Hepatol. 1999 Jul; 31(1):53-60. PMID: 10424283.
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    68. Wu J, Zern M. NF-kappa B, liposomes and pathogenesis of hepatic injury and fibrosis. Front Biosci. 1999 Jun 15; 4:D520-7. PMID: 10369809.
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    69. Wu J, Danielsson A, Zern M. Toxicity of hepatotoxins: new insights into mechanisms and therapy. Expert Opin Investig Drugs. 1999 May; 8(5):585-607. PMID: 15992118.
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    70. Di Campli C, Wu J, Zern M. Targeting of therapeutics to the liver: liposomes and viral vectors. Alcohol Clin Exp Res. 1999 May; 23(5):950-4. PMID: 10371421.
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    71. Di Campli C, Wu J, Gasbarrini A, Gasbarrini G, Zern M. Gene therapy for human liver diseases. Eur J Gastroenterol Hepatol. 1999 Apr; 11(4):421-9. PMID: 10321760.
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    72. Strayer DS, Zern M. Gene delivery to the liver using simian virus 40-derived vectors. Semin Liver Dis. 1999; 19(1):71-81. PMID: 10349685.
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    73. Zern M, Ozaki I, Duan L, Pomerantz R, Liu SL, Strayer DS. A novel SV40-based vector successfully transduces and expresses an alpha 1-antitrypsin ribozyme in a human hepatoma-derived cell line. Gene Ther. 1999 Jan; 6(1):114-20. PMID: 10341883.
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    74. Wu J, Wu GY, Zern M. The prospects of hepatic drug delivery and gene therapy. Expert Opin Investig Drugs. 1998 Nov; 7(11):1795-817. PMID: 15991930.
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    75. Wang JY, Guo JS, Li H, Liu SL, Zern M. Inhibitory effect of glycyrrhizin on NF-kappaB binding activity in CCl4- plus ethanol-induced liver cirrhosis in rats. Liver. 1998 Jun; 18(3):180-5. PMID: 9716228.
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    76. Wu J, Liu P, Zhu JL, Maddukuri S, Zern M. Increased liver uptake of liposomes and improved targeting efficacy by labeling with asialofetuin in rodents. Hepatology. 1998 Mar; 27(3):772-8. PMID: 9500706.
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    77. Kuncio GS, Tsyganskaya M, Zhu J, Liu SL, Nagy L, Thomazy V, Davies PJ, Zern M. TNF-alpha modulates expression of the tissue transglutaminase gene in liver cells. Am J Physiol. 1998 Feb; 274(2 Pt 1):G240-5. PMID: 9486175.
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    78. Zern M, Kresina TF. Hepatic drug delivery and gene therapy. Hepatology. 1997 Feb; 25(2):484-91. PMID: 9021968.
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    79. Mirza A, Liu SL, Frizell E, Zhu J, Maddukuri S, Martinez J, Davies P, Schwarting R, Norton P, Zern M. A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-kappaB. Am J Physiol. 1997 Feb; 272(2 Pt 1):G281-8. PMID: 9124352.
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    80. Glascott PA, Tsyganskaya M, Gilfor E, Zern M, Farber JL. The antioxidant function of the physiological content of vitamin C. Mol Pharmacol. 1996 Oct; 50(4):994-9. PMID: 8863846.
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    81. Wu J, Zern M. Modification of liposomes for liver targeting. J Hepatol. 1996 Jun; 24(6):757-63. PMID: 8835753.
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    82. Liu SL, Degli Esposti S, Yao T, Diehl AM, Zern M. Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology. 1995 Nov; 22(5):1474-81. PMID: 7590666.
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    83. Nguyen MT, Zern M. An ounce of prevention: the development of viral hepatitis vaccines. Compr Ther. 1995 Jun; 21(6):283-9. PMID: 7664539.
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    84. Frizell E, Liu SL, Abraham A, Ozaki I, Eghbali M, Sage EH, Zern M. Expression of SPARC in normal and fibrotic livers. Hepatology. 1995 Mar; 21(3):847-54. PMID: 7875683.
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    85. Arnon R, Esposti SD, Zern M. Molecular biological aspects of alcohol-induced liver disease. Alcohol Clin Exp Res. 1995 Feb; 19(1):247-56. PMID: 7771656.
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    86. Kresina TF, He Q, Degli Esposti S, Zern M. Gene expression of transforming growth factor beta 1 and extracellular matrix proteins in murine Schistosoma mansoni infection. Gastroenterology. 1994 Sep; 107(3):773-80. PMID: 8076764.
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    87. Yao T, Degli Esposti S, Huang L, Arnon R, Spangenberger A, Zern M. Inhibition of carbon tetrachloride-induced liver injury by liposomes containing vitamin E. Am J Physiol. 1994 Sep; 267(3 Pt 1):G476-84. PMID: 7943246.
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    88. Frizell E, Abraham A, Doolittle M, Bashey R, Kresina T, Van Thiel D, Zern M. FK506 enhances fibrogenesis in in vitro and in vivo models of liver fibrosis in rats. Gastroenterology. 1994 Aug; 107(2):492-8. PMID: 7518783.
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    89. Miao S, Suri PK, Shu-Ling L, Abraham A, Cook N, Milos P, Zern M. Role of the cyclic AMP response element in rat fibronectin gene expression. Hepatology. 1993 May; 17(5):882-90. PMID: 8387949.
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    90. Annoni G, Weiner FR, Zern M. Increased transforming growth factor-beta 1 gene expression in human liver disease. J Hepatol. 1992 Mar; 14(2-3):259-64. PMID: 1380023.
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    91. Sun MA, Wang BE, Annoni G, Degli Esposti S, Biempica L, Zern M. Two rat models of hepatic fibrosis. A morphologic and molecular comparison. Lab Invest. 1990 Oct; 63(4):467-75. PMID: 2232702.
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    92. Weiner FR, Giambrone MA, Czaja MJ, Shah A, Annoni G, Takahashi S, Eghbali M, Zern M. Ito-cell gene expression and collagen regulation. Hepatology. 1990 Jan; 11(1):111-7. PMID: 2295461.
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    93. Czaja MJ, Weiner FR, Takahashi S, Giambrone MA, van der Meide PH, Schellekens H, Biempica L, Zern M. Gamma-interferon treatment inhibits collagen deposition in murine schistosomiasis. Hepatology. 1989 Nov; 10(5):795-800. PMID: 2509321.
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    94. Czaja MJ, Weiner FR, Flanders KC, Giambrone MA, Wind R, Biempica L, Zern M. In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis. J Cell Biol. 1989 Jun; 108(6):2477-82. PMID: 2500447; PMCID: PMC2115595.
    95. Weiner FR, Shah A, Smith PJ, Rubin CS, Zern M. Regulation of collagen gene expression in 3T3-L1 cells. Effects of adipocyte differentiation and tumor necrosis factor alpha. Biochemistry. 1989 May 02; 28(9):4094-9. PMID: 2752011.
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    96. Weiner FR, Czaja MJ, Giambrone MA, Wu CH, Wu GY, Zern M. Development of molecular hybridization technology to evaluate albumin and procollagen mRNA content in baboons and man. Hepatology. 1987 Jan-Feb; 7(1 Suppl):19S-25S. PMID: 3804213.
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