Martin L Privalsky

Title(s)Professor, Microbiology and Molecular Genetics
SchoolUniversity of California, Davis
Address247B Briggs Hall
CA 95616
Phone530-752-3013
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    1. Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone α. Mol Cell Biol. 2022 02 17; 42(2):e0036321. Romartinez-Alonso B, Agostini M, Jones H, McLellan J, Sood DE, Tomkinson N, Marelli F, Gentile I, Visser WE, Schoenmakers E, Fairall L, Privalsky M, Moran C, Persani L, Chatterjee K, Schwabe JWR. PMID: 34871063; PMCID: PMC8852717.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    2. Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism. PLoS One. 2020; 15(10):e0241238. Goodson ML, Knotts TA, Campbell EL, Snyder CA, Young BM, Privalsky ML. PMID: 33104749; PMCID: PMC7588069.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals. BMC Res Notes. 2019 Jun 17; 12(1):343. Privalsky ML, Goodson ML. PMID: 31208445; PMCID: PMC6580476.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential. Thyroid. 2018 12; 28(12):1708-1722. Harrus D, Déméné H, Vasquez E, Boulahtouf A, Germain P, Figueira AC, Privalsky ML, Bourguet W, le Maire A. PMID: 30235988.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. A resistance to thyroid hormone syndrome mutant operates through the target gene repertoire of the wild-type thyroid hormone receptor. Mol Cell Endocrinol. 2017 05 15; 447:87-97. Jimenez R, Privalsky ML. PMID: 28257829.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Corepressor diversification by alternative mRNA splicing is species specific. BMC Evol Biol. 2016 10 19; 16(1):221. Privalsky ML, Snyder CA, Goodson ML. PMID: 27756201; PMCID: PMC5069798.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    7. Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling. Mol Cell Endocrinol. 2015 Sep 15; 413:228-35. Snyder CA, Goodson ML, Schroeder AC, Privalsky ML. PMID: 26166430; PMCID: PMC4556269.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    8. Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance. Mol Cell Biol. 2014 Nov 15; 34(22):4104-14. Goodson ML, Young BM, Snyder CA, Schroeder AC, Privalsky ML. PMID: 25182530; PMCID: PMC4248719.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    9. Thyroid hormones, t3 and t4, in the brain. Front Endocrinol (Lausanne). 2014; 5:40. Schroeder AC, Privalsky ML. PMID: 24744751; PMCID: PMC3978256.
      View in: PubMed   Mentions: 43     Fields:    
    10. The ability of thyroid hormone receptors to sense t4 as an agonist depends on receptor isoform and on cellular cofactors. Mol Endocrinol. 2014 May; 28(5):745-57. Schroeder A, Jimenez R, Young B, Privalsky ML. PMID: 24673558; PMCID: PMC4004778.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    11. The two major isoforms of thyroid hormone receptor, TRα1 and TRβ1, preferentially partner with distinct panels of auxiliary proteins. Mol Cell Endocrinol. 2014 Mar 05; 383(1-2):80-95. Hahm JB, Schroeder AC, Privalsky ML. PMID: 24325866.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Temporal comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the serum of second trimester pregnant women recruited from San Francisco General Hospital, California. Environ Sci Technol. 2013 Oct 15; 47(20):11776-84. Zota AR, Linderholm L, Park JS, Petreas M, Guo T, Privalsky ML, Zoeller RT, Woodruff TJ. PMID: 24066858; PMCID: PMC4086273.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    13. Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2. Mol Endocrinol. 2013 May; 27(5):840-59. Hahm JB, Privalsky ML. PMID: 23558175; PMCID: PMC3634115.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    14. Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. J Clin Invest. 2012 Jul; 122(7):2428-38. Sinha RA, You SH, Zhou J, Siddique MM, Bay BH, Zhu X, Privalsky ML, Cheng SY, Stevens RD, Summers SA, Newgard CB, Lazar MA, Yen PM. PMID: 22684107; PMCID: PMC3386813.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    15. SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and β. Mol Cell Endocrinol. 2012 Apr 04; 351(2):306-16. Mengeling BJ, Goodson ML, Bourguet W, Privalsky ML. PMID: 22266197; PMCID: PMC3288673.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    16. Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation. J Biol Chem. 2011 Dec 30; 286(52):44988-99. Goodson ML, Mengeling BJ, Jonas BA, Privalsky ML. PMID: 22065574; PMCID: PMC3247966.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    17. NCoR1 regulates thyroid hormone receptor isoform-dependent adipogenesis. J Mol Endocrinol. 2011 Jun; 46(3):233-44. Zhu XG, Kim DW, Goodson ML, Privalsky ML, Cheng SY. PMID: 21389087; PMCID: PMC3457783.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Thyroid hormone receptor mutations in cancer and resistance to thyroid hormone: perspective and prognosis. J Thyroid Res. 2011; 2011:361304. Rosen MD, Privalsky ML. PMID: 21760978; PMCID: PMC3134260.
      View in: PubMed   Mentions: 13  
    19. A mechanism for pituitary-resistance to thyroid hormone (PRTH) syndrome: a loss in cooperative coactivator contacts by thyroid hormone receptor (TR)beta2. Mol Endocrinol. 2011 Jul; 25(7):1111-25. Lee S, Young BM, Wan W, Chan IH, Privalsky ML. PMID: 21622532; PMCID: PMC3125096.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    20. Mutant thyroid hormone receptors (TRs) isolated from distinct cancer types display distinct target gene specificities: a unique regulatory repertoire associated with two renal clear cell carcinomas. Mol Endocrinol. 2011 Aug; 25(8):1311-25. Rosen MD, Chan IH, Privalsky ML. PMID: 21622534; PMCID: PMC3146248.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants. J Biol Chem. 2011 Feb 11; 286(6):4236-47. Mengeling BJ, Phan TQ, Goodson ML, Privalsky ML. PMID: 21131350; PMCID: PMC3039402.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    22. Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation. Mol Cell Endocrinol. 2011 Jan 30; 332(1-2):180-8. Varlakhanova N, Hahm JB, Privalsky ML. PMID: 20965228; PMCID: PMC3011023.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    23. Nuclear receptor coregulators as a new paradigm for therapeutic targeting. Adv Drug Deliv Rev. 2010 Oct 30; 62(13):1227-37. Hsia EY, Goodson ML, Zou JX, Privalsky ML, Chen HW. PMID: 20933027; PMCID: PMC5004779.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    24. Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain. Mol Cell Biol. 2010 Mar; 30(6):1434-45. Varlakhanova N, Snyder C, Jose S, Hahm JB, Privalsky ML. PMID: 20065040; PMCID: PMC2832498.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    25. A conserved lysine in the thyroid hormone receptor-alpha1 DNA-binding domain, mutated in hepatocellular carcinoma, serves as a sensor for transcriptional regulation. Mol Cancer Res. 2010 Jan; 8(1):15-23. Chan IH, Privalsky ML. PMID: 20053725; PMCID: PMC2808454.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    26. DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified. Mol Cell Endocrinol. 2010 May 05; 319(1-2):88-98. Phan TQ, Jow MM, Privalsky ML. PMID: 19945505; PMCID: PMC3270409.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    27. Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire. Oncogene. 2009 Nov 26; 28(47):4162-74. Chan IH, Privalsky ML. PMID: 19749797; PMCID: PMC2787677.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    28. Isoform-specific transcriptional activity of overlapping target genes that respond to thyroid hormone receptors alpha1 and beta1. Mol Endocrinol. 2009 Nov; 23(11):1758-75. Chan IH, Privalsky ML. PMID: 19628582; PMCID: PMC2775939.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    29. The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. J Biol Chem. 2009 Jul 17; 284(29):19554-63. Privalsky ML, Lee S, Hahm JB, Young BM, Fong RN, Chan IH. PMID: 19487700; PMCID: PMC2740581.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    30. Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity. Mol Endocrinol. 2009 Aug; 23(8):1183-92. Rosen MD, Privalsky ML. PMID: 19407221; PMCID: PMC2718749.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    31. High throughput analysis of nuclear receptor-cofactor interactions. Methods Mol Biol. 2009; 505:157-69. Goodson ML, Farboud B, Privalsky ML. PMID: 19117144.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    32. A cautionary note as to the use of pBi-L and related luciferase/transgenic vectors in the study of thyroid endocrinology. Thyroid. 2008 Jun; 18(6):665-6. Chan IH, Borowsky AD, Privalsky ML. PMID: 18578620; PMCID: PMC2962860.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    33. Coactivator recruitment is enhanced by thyroid hormone receptor trimers. Mol Cell Endocrinol. 2008 Jan 02; 280(1-2):47-62. Mengeling BJ, Lee S, Privalsky ML. PMID: 18006144; PMCID: PMC2197157.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    34. Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing. Mol Endocrinol. 2007 Aug; 21(8):1924-39. Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML. PMID: 17519355; PMCID: PMC2675559.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    35. An improved high throughput protein-protein interaction assay for nuclear hormone receptors. Nucl Recept Signal. 2007 Mar 09; 5:e002. Goodson ML, Farboud B, Privalsky ML. PMID: 17464356; PMCID: PMC1853068.
      View in: PubMed   Mentions: 10     Fields:    
    36. Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs. Oncogene. 2006 Jun 15; 25(25):3576-88. Chan IH, Privalsky ML. PMID: 16434963; PMCID: PMC2701908.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    37. Multiple mutations contribute to repression by the v-Erb A oncoprotein. Oncogene. 2005 Oct 13; 24(45):6737-52. Lee S, Privalsky ML. PMID: 16007162; PMCID: PMC2706103.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    38. Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness. J Neurochem. 2005 Apr; 93(1):171-85. McKenzie GJ, Stevenson P, Ward G, Papadia S, Bading H, Chawla S, Privalsky M, Hardingham GE. PMID: 15773917.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    39. Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function. Mol Endocrinol. 2005 Jun; 19(6):1529-42. Wan W, Farboud B, Privalsky ML. PMID: 15802373.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    40. Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties. Mol Endocrinol. 2005 Apr; 19(4):863-78. Lee S, Privalsky ML. PMID: 15650024; PMCID: PMC2675561.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    41. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. J Biol Chem. 2005 Mar 04; 280(9):7493-503. Goodson ML, Jonas BA, Privalsky ML. PMID: 15632172; PMCID: PMC2720035.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    42. Identification of a novel MAGE D2 antisense RNA transcript in human tissues. Biochem Biophys Res Commun. 2004 Nov 05; 324(1):199-204. Harper R, Xu C, Di P, Chen Y, Privalsky M, Wu R. PMID: 15465002.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    43. SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways. J Biol Chem. 2004 Dec 24; 279(52):54676-86. Jonas BA, Privalsky ML. PMID: 15491994; PMCID: PMC2653424.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    44. Novel mode of deoxyribonucleic acid recognition by thyroid hormone receptors: thyroid hormone receptor beta-isoforms can bind as trimers to natural response elements comprised of reiterated half-sites. Mol Endocrinol. 2005 Jan; 19(1):35-51. Mengeling BJ, Pan F, Privalsky ML. PMID: 15459250.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    45. Retinoic acid receptor-alpha is stabilized in a repressive state by its C-terminal, isotype-specific F domain. Mol Endocrinol. 2004 Dec; 18(12):2839-53. Farboud B, Privalsky ML. PMID: 15331758.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    46. Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis. Cancer Cell. 2004 Apr; 5(4):389-401. Hayakawa F, Privalsky ML. PMID: 15093545.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    47. Functional regulation of GATA-2 by acetylation. J Leukoc Biol. 2004 Mar; 75(3):529-40. Hayakawa F, Towatari M, Ozawa Y, Tomita A, Privalsky ML, Saito H. PMID: 15001660.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    48. The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu Rev Physiol. 2004; 66:315-60. Privalsky ML. PMID: 14977406.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    49. Activation incarnate. Dev Cell. 2003 Jul; 5(1):1-2. Privalsky ML. PMID: 12852843.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    50. Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression. Mol Cell Biol. 2003 Apr; 23(8):2844-58. Farboud B, Hauksdottir H, Wu Y, Privalsky ML. PMID: 12665583; PMCID: PMC152560.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    51. Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand. Mol Endocrinol. 2003 Mar; 17(3):373-85. Hauksdottir H, Farboud B, Privalsky ML. PMID: 12554770.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    52. Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain. Mol Cell Biol. 2002 Mar; 22(6):1626-38. Ruse MD, Privalsky ML, Sladek FM. PMID: 11865043; PMCID: PMC135595.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    53. Molecular analysis of human resistance to thyroid hormone syndrome. Methods Mol Biol. 2002; 202:129-52. Yoh SM, Privalsky ML. PMID: 12094601.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    54. Isoform-specific transcriptional regulation by thyroid hormone receptors: hormone-independent activation operates through a steroid receptor mode of co-activator interaction. Mol Endocrinol. 2001 Jul; 15(7):1170-85. Yang Z, Privalsky ML. PMID: 11435616.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    55. The SMRT corepressor is a target of phosphorylation by protein kinase CK2 (casein kinase II). Mol Cell Biochem. 2001 Apr; 220(1-2):1-13. Zhou Y, Gross W, Hong SH, Privalsky ML. PMID: 11451368; PMCID: PMC2655343.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    56. Transcriptional repression by thyroid hormone receptors. A role for receptor homodimers in the recruitment of SMRT corepressor. J Biol Chem. 2001 May 18; 276(20):16857-67. Yoh SM, Privalsky ML. PMID: 11278601.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    57. DNA recognition by the aberrant retinoic acid receptors implicated in human acute promyelocytic leukemia. Cell Growth Differ. 2001 Feb; 12(2):85-98. Hauksdóttir H, Privalsky ML. PMID: 11243468; PMCID: PMC2712924.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    58. Regulation of SMRT and N-CoR corepressor function. Curr Top Microbiol Immunol. 2001; 254:117-36. Privalsky ML. PMID: 11190570.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    59. The SMRT corepressor is regulated by a MEK-1 kinase pathway: inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export. Mol Cell Biol. 2000 Sep; 20(17):6612-25. Hong SH, Privalsky ML. PMID: 10938135; PMCID: PMC86146.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    60. Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable. Blood. 2000 Mar 01; 95(5):1541-50. Kogan SC, Hong SH, Shultz DB, Privalsky ML, Bishop JM. PMID: 10688806.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    61. Resistance to thyroid hormone (RTH) syndrome reveals novel determinants regulating interaction of T3 receptor with corepressor. Mol Cell Endocrinol. 2000 Jan 25; 159(1-2):109-24. Yoh SM, Privalsky ML. PMID: 10687857.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    62. Transcriptional anti-repression. Thyroid hormone receptor beta-2 recruits SMRT corepressor but interferes with subsequent assembly of a functional corepressor complex. J Biol Chem. 1999 Dec 24; 274(52):37131-8. Yang Z, Hong SH, Privalsky ML. PMID: 10601274; PMCID: PMC2701910.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    63. Retinoid isomers differ in the ability to induce release of SMRT corepressor from retinoic acid receptor-alpha. J Biol Chem. 1999 Jan 29; 274(5):2885-92. Hong SH, Privalsky ML. PMID: 9915825; PMCID: PMC2701912.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    64. Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6. J Biol Chem. 1998 Oct 16; 273(42):27695-702. Wong CW, Privalsky ML. PMID: 9765306.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    65. Transcriptional silencing is defined by isoform- and heterodimer-specific interactions between nuclear hormone receptors and corepressors. Mol Cell Biol. 1998 Oct; 18(10):5724-33. Wong CW, Privalsky ML. PMID: 9742089; PMCID: PMC109158.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    66. Transcriptional repression by the SMRT-mSin3 corepressor: multiple interactions, multiple mechanisms, and a potential role for TFIIB. Mol Cell Biol. 1998 Sep; 18(9):5500-10. Wong CW, Privalsky ML. PMID: 9710634; PMCID: PMC109135.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    67. Signaling by tyrosine kinases negatively regulates the interaction between transcription factors and SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) corepressor. Mol Endocrinol. 1998 Aug; 12(8):1161-71. Hong SH, Wong CW, Privalsky ML. PMID: 9717842; PMCID: PMC2653426.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    68. Phosphorylation of thyroid hormone receptors by protein kinase A regulates DNA recognition by specific inhibition of receptor monomer binding. J Biol Chem. 1998 May 01; 273(18):10926-32. Tzagarakis-Foster C, Privalsky ML. PMID: 9556570.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    69. Depudecin makes a debut. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3335-7. Privalsky ML. PMID: 9520362; PMCID: PMC33845.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    70. A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release. Mol Cell Biol. 1997 Oct; 17(10):6131-8. Lin BC, Hong SH, Krig S, Yoh SM, Privalsky ML. PMID: 9315673; PMCID: PMC232463.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    71. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9028-33. Hong SH, David G, Wong CW, Dejean A, Privalsky ML. PMID: 9256429; PMCID: PMC23013.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    72. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 1997 Aug 08; 90(3):569-80. Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. PMID: 9267036.
      View in: PubMed   Mentions: 408     Fields:    Translation:HumansAnimalsCells
    73. Retinoid X and retinoic acid receptors interact with transcription factor II-B by distinct mechanisms. Mol Cell Endocrinol. 1997 Apr 25; 129(1):55-61. Chen HW, Privalsky ML. PMID: 9175629.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    74. Plasticity of tetramer formation by retinoid X receptors. An alternative paradigm for DNA recognition. J Biol Chem. 1997 Apr 11; 272(15):9860-7. Lin BC, Wong CW, Chen HW, Privalsky ML. PMID: 9092522.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    75. Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors. Mol Endocrinol. 1997 Apr; 11(4):470-80. Yoh SM, Chatterjee VK, Privalsky ML. PMID: 9092799; PMCID: PMC2725002.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    76. Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors. Mol Endocrinol. 1996 Jul; 10(7):813-25. Sande S, Privalsky ML. PMID: 8813722.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    77. DNA recognition by normal and oncogenic thyroid hormone receptors. Unexpected diversity in half-site specificity controlled by non-zinc-finger determinants. J Biol Chem. 1996 May 03; 271(18):10800-5. Judelson C, Privalsky ML. PMID: 8631892.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    78. Role of the N terminus in DNA recognition by the v-erb A protein, an oncogenic derivative of a thyroid hormone receptor. Mol Endocrinol. 1995 May; 9(5):551-62. Wong CW, Privalsky ML. PMID: 7565803.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    79. Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition. Proc Natl Acad Sci U S A. 1995 Jan 17; 92(2):422-6. Chen H, Privalsky ML. PMID: 7831303; PMCID: PMC42752.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    80. Reconstitution of thyroid hormone receptor and retinoic acid receptor function in the fission yeast Schizosaccharomyces pombe. Mol Endocrinol. 1994 Nov; 8(11):1455-64. Sande S, Privalsky ML. PMID: 7877615.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    81. DNA sequence specificity of the v-erb A oncoprotein/thyroid hormone receptor: role of the P-box and its interaction with more N-terminal determinants of DNA recognition. Mol Endocrinol. 1994 Jul; 8(7):819-28. Smit-McBride Z, Privalsky ML. PMID: 7984144.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    82. The erbA oncogene represses the actions of both retinoid X and retinoid A receptors but does so by distinct mechanisms. Mol Cell Biol. 1993 Oct; 13(10):5970-80. Chen HW, Privalsky ML. PMID: 8105369; PMCID: PMC364641.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    83. Reconstitution of retinoid X receptor function and combinatorial regulation of other nuclear hormone receptors in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1993 Aug 01; 90(15):6929-33. Hall BL, Smit-McBride Z, Privalsky ML. PMID: 8394003; PMCID: PMC47048.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    84. Functional domains of the v-erbA protein necessary for oncogenesis are required for transcriptional activation in Saccharomyces cerevisiae. Oncogene. 1993 Jun; 8(6):1465-75. Smit-McBride Z, Privalsky ML. PMID: 8099219.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    85. Nuclear hormone receptors involved in neoplasia: erb A exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domain. Mol Cell Biol. 1993 Apr; 13(4):2366-76. Chen H, Smit-McBride Z, Lewis S, Sharif M, Privalsky ML. PMID: 8096060; PMCID: PMC359557.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    86. v-erb A, nuclear hormone receptors, and oncogenesis. Biochim Biophys Acta. 1992 Sep 14; 1114(1):51-62. Privalsky ML. PMID: 1356442.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    87. V-erbA and c-erbA proteins enhance transcriptional activation by c-jun. Oncogene. 1992 May; 7(5):953-60. Sharif M, Privalsky ML. PMID: 1349165.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    88. Retinoid and thyroid hormone receptors: ligand-regulated transcription factors as proto-oncogenes. Semin Cell Biol. 1992 Apr; 3(2):99-106. Privalsky ML. PMID: 1319230.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    89. Functional interaction between the two zinc finger domains of the v-erb A oncoprotein. Cell Growth Differ. 1992 Apr; 3(4):207-16. Hall BL, Bonde BG, Judelson C, Privalsky ML. PMID: 1355356.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    90. v-erbA oncogene function in neoplasia correlates with its ability to repress retinoic acid receptor action. Cell. 1991 Sep 06; 66(5):885-93. Sharif M, Privalsky ML. PMID: 1679679.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    91. Ontogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA function. J Virol. 1991 Apr; 65(4):2037-46. Bonde BG, Sharif M, Privalsky ML. PMID: 1672166; PMCID: PMC240051.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    92. A subpopulation of the v-erb A oncogene protein, a derivative of a thyroid hormone receptor, associates with heat shock protein 90. J Biol Chem. 1991 Jan 25; 266(3):1456-62. Privalsky ML. PMID: 1671036.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    93. The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast. Cell. 1990 Dec 21; 63(6):1277-86. Privalsky ML, Sharif M, Yamamoto KR. PMID: 1979758.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    94. Mapping of functional domains within the v-erb A oncogene protein: the remnants of the hormone binding domain play multiple, vital roles in protein action. Oncogene. 1990 Sep; 5(9):1303-11. Boucher P, Privalsky ML. PMID: 2170895.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    95. Sequence-specific DNA binding by the v-erbA oncogene protein of avian erythroblastosis virus. J Virol. 1990 Mar; 64(3):1314-20. Bonde BG, Privalsky ML. PMID: 1968105; PMCID: PMC249249.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    96. A subpopulation of the avian erythroblastosis virus v-erbA protein, a member of the nuclear hormone receptor family, is glycosylated. J Virol. 1990 Jan; 64(1):463-6. Privalsky ML. PMID: 1967151; PMCID: PMC249128.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    97. Genetic dissection of functional domains within the avian erythroblastosis virus v-erbA oncogene. Mol Cell Biol. 1988 Oct; 8(10):4510-7. Privalsky ML, Boucher P, Koning A, Judelson C. PMID: 2847034; PMCID: PMC365526.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    98. The avian erythroblastosis virus erbA oncogene encodes a DNA-binding protein exhibiting distinct nuclear and cytoplasmic subcellular localizations. J Virol. 1988 Feb; 62(2):534-44. Boucher P, Koning A, Privalsky ML. PMID: 2826814; PMCID: PMC250565.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    99. Orientation of the v-erb-B gene product in the plasma membrane. Mol Cell Biol. 1986 Apr; 6(4):1329-33. Schatzman RC, Evan GI, Privalsky ML, Bishop JM. PMID: 3023882; PMCID: PMC367647.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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