Nilesh W Gaikwad

InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nuttall JR, Kucera HR, Supasai S, Gaikwad N, Oteiza PI. Combined Effects of Gestational Phthalate Exposure and Zinc Deficiency on Steroid Metabolism and Growth. Toxicol Sci. 2017 04 01; 156(2):469-479. PMID: 28115639.
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    2. Silva DO, Seifert M, Nora FR, Bobrowski VL, Freitag RA, Kucera HR, Nora L, Gaikwad N. Acute Toxicity and Cytotoxicity of Pereskia aculeata, a Highly Nutritious Cactaceae Plant. J Med Food. 2017 Apr; 20(4):403-409. PMID: 28355092.
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    3. Bettaieb A, Hosein E, Chahed S, Abdulaziz A, Kucera HR, Gaikwad N, Haj FG. Decreased adiposity and enhanced glucose tolerance in shikonin treated mice. Obesity (Silver Spring). 2015 Nov; 23(11):2269-77. PMID: 26374090; PMCID: PMC4710365 [Available on 11/01/16].
    4. Chai X, Guo Y, Jiang M, Hu B, Li Z, Fan J, Deng M, Billiar TR, Kucera HR, Gaikwad N, Xu M, Lu P, Yan J, Fu H, Liu Y, Yu L, Huang M, Zeng S, Xie W. Oestrogen sulfotransferase ablation sensitizes mice to sepsis. Nat Commun. 2015 Aug 10; 6:7979. PMID: 26259151; PMCID: PMC4532951.
    5. Guo Y, Hu B, Huang H, Tsung A, Gaikwad N, Xu M, Jiang M, Ren S, Fan J, Billiar TR, Huang M, Xie W. Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury. J Biol Chem. 2015 Jun 05; 290(23):14754-64. PMID: 25922074; PMCID: PMC4505540.
    6. Liu C, Lou W, Zhu Y, Yang JC, Nadiminty N, Gaikwad N, Evans CP, Gao AC. Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer. Cancer Res. 2015 Apr 01; 75(7):1413-22. PMID: 25649766; PMCID: PMC4383695.
    7. Krishnan S, Gustafson MB, Campbell C, Gaikwad N, Keim NL. Association between circulating endogenous androgens and insulin sensitivity changes with exercise training in midlife women. Menopause. 2014 Sep; 21(9):967-74. PMID: 24496084.
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    8. Jiang M, He J, Kucera H, Gaikwad N, Zhang B, Xu M, O'Doherty RM, Selcer KW, Xie W. Hepatic overexpression of steroid sulfatase ameliorates mouse models of obesity and type 2 diabetes through sex-specific mechanisms. J Biol Chem. 2014 Mar 21; 289(12):8086-97. PMID: 24497646; PMCID: PMC3961640.
    9. Powis TG, Gallaga Murrieta E, Lesure R, Lopez Bravo R, Grivetti L, Kucera H, Gaikwad N. Prehispanic use of chili peppers in Chiapas, Mexico. PLoS One. 2013; 8(11):e79013. PMID: 24236083; PMCID: PMC3827288.
    10. Gaikwad N. Mass spectrometry evidence for formation of estrogen-homocysteine conjugates: estrogens can regulate homocysteine levels. Free Radic Biol Med. 2013 Dec; 65:1447-54. PMID: 23928335.
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    11. Gaikwad N. Metabolomic profiling unravels DNA adducts in human breast that are formed from peroxidase mediated activation of estrogens to quinone methides. PLoS One. 2013; 8(6):e65826. PMID: 23762435; PMCID: PMC3675060.
    12. Gaikwad N. Ultra performance liquid chromatography-tandem mass spectrometry method for profiling of steroid metabolome in human tissue. Anal Chem. 2013 May 21; 85(10):4951-60. PMID: 23597399.
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    13. Zuno-Floriano FG, Holstege D, Hengel MJ, Gaikwad N, Aldana-Madrid ML, Miller MG. Determination of vitamin A and its metabolites in rat testis: possible involvement of vitamin A in testicular toxicity caused by molinate. Bull Environ Contam Toxicol. 2012 Jun; 88(6):1038-42. PMID: 22456730; PMCID: PMC3339053.
    14. Zuno-Floriano FG, Miller MG, Aldana-Madrid ML, Hengel MJ, Gaikwad N, Tolstikov V, Contreras-Cort├ęs AG. Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. PLoS One. 2012; 7(2):e31221. PMID: 22363586; PMCID: PMC3281949.
    15. Gaikwad N, Bodell WJ. Peroxidase-mediated dealkylation of tamoxifen, detected by electrospray ionization-mass spectrometry, and activation to form DNA adducts. Free Radic Biol Med. 2012 Jan 15; 52(2):340-7. PMID: 22064363; PMCID: PMC3253372.
    16. Gaikwad N, Murman D, Beseler CL, Zahid M, Rogan EG, Cavalieri EL. Imbalanced estrogen metabolism in the brain: possible relevance to the etiology of Parkinson's disease. Biomarkers. 2011 Aug; 16(5):434-44. PMID: 21692648; PMCID: PMC3142324.
    17. Gaikwad N, Yang L, Weisenburger DD, Vose J, Beseler C, Rogan EG, Cavalieri EL. Urinary biomarkers suggest that estrogen-DNA adducts may play a role in the aetiology of non-Hodgkin lymphoma. Biomarkers. 2009 Nov; 14(7):502-12. PMID: 19863189; PMCID: PMC4423407.
    18. Singh S, Zahid M, Saeed M, Gaikwad N, Meza JL, Cavalieri EL, Rogan EG, Chakravarti D. NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells. J Steroid Biochem Mol Biol. 2009 Oct; 117(1-3):56-66. PMID: 19628038; PMCID: PMC4425209.
    19. Saeed M, Higginbotham S, Gaikwad N, Chakravarti D, Rogan E, Cavalieri E. Depurinating naphthalene-DNA adducts in mouse skin related to cancer initiation. Free Radic Biol Med. 2009 Oct 01; 47(7):1075-81. PMID: 19619639; PMCID: PMC4424927.
    20. Yang L, Gaikwad N, Meza J, Cavalieri EL, Muti P, Trock B, Rogan EG. Novel biomarkers for risk of prostate cancer: results from a case-control study. Prostate. 2009 Jan 01; 69(1):41-8. PMID: 18816637; PMCID: PMC2588647.
    21. Gaikwad N, Yang L, Rogan EG, Cavalieri EL. Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones. Free Radic Biol Med. 2009 Jan 15; 46(2):253-62. PMID: 18996184; PMCID: PMC2746554.
    22. Gaikwad N, Yang L, Muti P, Meza JL, Pruthi S, Ingle JN, Rogan EG, Cavalieri EL. The molecular etiology of breast cancer: evidence from biomarkers of risk. Int J Cancer. 2008 May 01; 122(9):1949-57. PMID: 18098283; PMCID: PMC4422386.
    23. Zahid M, Gaikwad N, Ali MF, Lu F, Saeed M, Yang L, Rogan EG, Cavalieri EL. Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol. Free Radic Biol Med. 2008 Jul 15; 45(2):136-45. PMID: 18423413; PMCID: PMC2494714.
    24. Zahid M, Gaikwad N, Rogan EG, Cavalieri EL. Inhibition of depurinating estrogen-DNA adduct formation by natural compounds. Chem Res Toxicol. 2007 Dec; 20(12):1947-53. PMID: 18039013.
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    25. Zahid M, Saeed M, Lu F, Gaikwad N, Rogan E, Cavalieri E. Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation. Free Radic Biol Med. 2007 Dec 01; 43(11):1534-40. PMID: 17964424; PMCID: PMC2096412.
    26. Gaikwad N, Rogan EG, Cavalieri EL. Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones. Free Radic Biol Med. 2007 Nov 01; 43(9):1289-98. PMID: 17893042; PMCID: PMC2064005.
    27. Zhang Y, Gaikwad N, Olson K, Zahid M, Cavalieri EL, Rogan EG. Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. Metabolism. 2007 Jul; 56(7):887-94. PMID: 17570247.
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    28. Chakravarti D, Zahid M, Backora M, Myers EM, Gaikwad N, Weisenburger DD, Cavalieri EL, Rogan EG, Joshi SS. Ortho-quinones of benzene and estrogens induce hyperproliferation of human peripheral blood mononuclear cells. Leuk Lymphoma. 2006 Dec; 47(12):2635-44. PMID: 17169809.
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    29. Bodell WJ, Gaikwad N, Miller D, Berger MS. Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors. Cancer Epidemiol Biomarkers Prev. 2003 Jun; 12(6):545-51. PMID: 12815001.
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    30. Gaikwad N, Bodell WJ. Formation of DNA adducts in HL-60 cells treated with the toluene metabolite p-cresol: a potential biomarker for toluene exposure. Chem Biol Interact. 2003 May 06; 145(2):149-58. PMID: 12686491.
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