Thomas Semrad

Title(s)Associate Clinical Professor, Hematology and Oncology
SchoolUniversity of California, Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. EGFR High Copy Number Together With High EGFR Protein Expression Predicts Improved Outcome for Cetuximab-based Therapy in Squamous Cell Lung Cancer: Analysis From SWOG S0819, a Phase III Trial of Chemotherapy With or Without Cetuximab in Advanced NSCLC. Clin Lung Cancer. 2022 01; 23(1):60-71. Hirsch FR, Redman MW, Moon J, Agustoni F, Herbst RS, Semrad TJ, Varella-Garcia M, Rivard CJ, Kelly K, Gandara DR, Mack PC. PMID: 34753703; PMCID: PMC8766941.
      View in: PubMed   Mentions:
    2. Phase 1 study of alisertib (MLN8237) and weekly irinotecan in adults with advanced solid tumors. Cancer Chemother Pharmacol. 2021 08; 88(2):335-341. Semrad TJ, Kim EJ, Gong IY, Li T, Christensen S, Arora M, Riess JW, Gandara DR, Kelly K. PMID: 33993383; PMCID: PMC8259450.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. Influence of Socioeconomic Status on Incident Medical Conditions in Two-Year Survivors of Adolescent or Young Adult Differentiated Thyroid Cancer. J Adolesc Young Adult Oncol. 2021 10; 10(5):521-533. Semrad TJ, Li Q, Goldfarb M, Semrad A, Campbell M, Farwell DG, Keegan THM. PMID: 33512275; PMCID: PMC8666796.
      View in: PubMed   Mentions:    Fields:    
    4. Oxaliplatin-DNA Adducts as Predictive Biomarkers of FOLFOX Response in Colorectal Cancer: A Potential Treatment Optimization Strategy. Mol Cancer Ther. 2020 04; 19(4):1070-1079. Zimmermann M, Li T, Semrad TJ, Wu CY, Yu A, Cimino G, Malfatti M, Haack K, Turteltaub KW, Pan CX, Cho M, Kim EJ, Henderson PT. PMID: 32029633; PMCID: PMC7192311.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion. J Clin Oncol. 2019 06 20; 37(18):1578-1589. Adelstein DJ, Ismaila N, Ku JA, Burtness B, Swiecicki PL, Mell L, Beitler JJ, Gross N, Jones CU, Kaufman M, Le QT, Semrad TJ, Siu LL, Ridge JA. PMID: 31021656.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    6. Randomized Phase 2 Study of Trebananib (AMG 386) with or without Continued Anti-Vascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma Who Have Progressed on Bevacizumab, Pazopanib, Sorafenib, or Sunitinib - Results of NCI/CTEP Protocol 9048. Kidney Cancer. 2019 Feb 05; 3(1):51-61. Semrad TJ, Groshen S, Luo C, Pal S, Vaishampayan U, Joshi M, Quinn DI, Mack PC, Gandara DR, Lara PN. PMID: 30854497; PMCID: PMC6400131.
      View in: PubMed   Mentions: 2  
    7. Significant Clinical Response to a MEK Inhibitor Therapy in a Patient With Metastatic Melanoma Harboring an RAF1 Fusion. JCO Precis Oncol. 2018 Nov; 2:1-6. Kim KB, Semrad T, Schrock AB, Ali SM, Ross JS, Singer M, Kashani-Sabet M. PMID: 35135096.
      View in: PubMed   Mentions:
    8. A phase I trial of topotecan plus tivantinib in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2018 10; 82(4):723-732. Liu SV, Groshen SG, Kelly K, Reckamp KL, Belani C, Synold TW, Goldkorn A, Gitlitz BJ, Cristea MC, Gong IY, Semrad TJ, Xu Y, Xu T, Koczywas M, Gandara DR, Newman EM. PMID: 30128950; PMCID: PMC6342617.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    9. Predictors of Neck Reoperation and Mortality After Initial Total Thyroidectomy for Differentiated Thyroid Cancer. Thyroid. 2018 09; 28(9):1143-1152. Semrad TJ, Keegan THM, Semrad A, Brunson A, Farwell DG. PMID: 29929451; PMCID: PMC6154449.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma. Cancer Chemother Pharmacol. 2018 05; 81(5):957-963. El-Khoueiry AB, O'Donnell R, Semrad TJ, Mack P, Blanchard S, Bahary N, Jiang Y, Yen Y, Wright J, Chen H, Lenz HJ, Gandara DR. PMID: 29520435; PMCID: PMC6330274.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    11. Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview. Methods Mol Biol. 2018; 1765:281-297. Lin PS, Semrad TJ. PMID: 29589315.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG S0819): a randomised, phase 3 study. Lancet Oncol. 2018 01; 19(1):101-114. Herbst RS, Redman MW, Kim ES, Semrad TJ, Bazhenova L, Masters G, Oettel K, Guaglianone P, Reynolds C, Karnad A, Arnold SM, Varella-Garcia M, Moon J, Mack PC, Blanke CD, Hirsch FR, Kelly K, Gandara DR. PMID: 29169877; PMCID: PMC5847342.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    13. Mediating Effect of Postsurgical Chemotherapy on Presence of Dementia and Survival among Patients 65 and Older with Stage III Colon Cancer. Cancer Epidemiol Biomarkers Prev. 2017 10; 26(10):1558-1563. Chen Y, Cress RD, Stewart SL, Semrad TJ, Harvey D, Tencredi DJ, Beckett L. PMID: 28939585; PMCID: PMC7489435.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Phase II Study of Dovitinib in Patients Progressing on Anti-Vascular Endothelial Growth Factor Therapy. Cancer Treat Res Commun. 2017; 10:21-26. Semrad TJ, Kim EJ, Tanaka MS, Sands J, Roberts C, Burich RA, Li Y, Gandara DR, Lara P, Mack PC. PMID: 28736761; PMCID: PMC5519297.
      View in: PubMed   Mentions: 9     Fields:    
    15. Are there disparities in the presentation, treatment and outcomes of patients diagnosed with medullary thyroid cancer?-An analysis of 634 patients from the California Cancer Registry. Gland Surg. 2016 Aug; 5(4):398-404. Cox C, Chen Y, Cress R, Semrad AM, Semrad T, Gosnell JE, Campbell MJ. PMID: 27563561; PMCID: PMC4971346.
      View in: PubMed   Mentions: 2  
    16. The Role of Image-guided Radiotherapy in the Treatment of Anorectal Cancer Using Prone Belly-board Positioning. Anticancer Res. 2016 Jun; 36(6):3013-7. Miyamoto J, Michaud AL, Harandi NK, Kim EJ, Semrad T, Khatri V, Mayadev J, Perks J, Monjazeb AM. PMID: 27272819.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Molecular testing to optimize therapeutic decision making in advanced colorectal cancer. J Gastrointest Oncol. 2016 Apr; 7(Suppl 1):S11-20. Semrad TJ, Kim EJ. PMID: 27034809; PMCID: PMC4783624.
      View in: PubMed   Mentions: 4  
    18. ASCO 2015 update on gastrointestinal cancer: Checkpoint inhibition, multimodality strategies and secondary prevention. Surg Oncol. 2015 Dec; 24(4):371-4. Semrad TJ. PMID: 26646090; PMCID: PMC4688068.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    19. Disease Control Rate at 8 Weeks Predicts Subsequent Survival in Platinum-Treated Extensive Stage Small-Cell Lung Cancer: Results From the Southwest Oncology Group (SWOG) Database. Clin Lung Cancer. 2016 Mar; 17(2):113-8.e1-2. Lara PN, Moon J, Redman MW, Semrad TJ, Kelly K, Allen J, Gitlitz B, Mack PC, Gandara DR. PMID: 26498504; PMCID: PMC4789142.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    20. Integrating Chemotherapy into the Management of Oligometastatic Colorectal Cancer: Evidence-Based Approach Using Clinical Trial Findings. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S855-62. Semrad TJ, Fahrni AR, Gong IY, Khatri VP. PMID: 26100816; PMCID: PMC4688202.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Phase II clinical trials on investigational drugs for the treatment of pancreatic cancers. Expert Opin Investig Drugs. 2015 Jun; 24(6):781-94. Kim EJ, Semrad TJ, Bold RJ. PMID: 25809274; PMCID: PMC4684166.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Initial treatment patterns in younger adult patients with differentiated thyroid cancer in California. Thyroid. 2015 May; 25(5):509-13. Semrad TJ, Semrad AM, Farwell DG, Chen Y, Cress R. PMID: 25744759; PMCID: PMC4426319.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Implications of lymph node retrieval in locoregional rectal cancer treated with chemoradiotherapy: a California Cancer Registry Study. Eur J Surg Oncol. 2015 May; 41(5):647-52. Gill A, Brunson A, Lara P, Khatri V, Semrad TJ. PMID: 25800934; PMCID: PMC4406634.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors. Clin Cancer Res. 2015 Jun 01; 21(11):2480-6. Tomlinson BK, Thomson JA, Bomalaski JS, Diaz M, Akande T, Mahaffey N, Li T, Dutia MP, Kelly K, Gong IY, Semrad T, Gandara DR, Pan CX, Lara PN. PMID: 25739672; PMCID: PMC4452427.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    25. Relevance of platinum-sensitivity status in relapsed/refractory extensive-stage small-cell lung cancer in the modern era: a patient-level analysis of southwest oncology group trials. J Thorac Oncol. 2015 Jan; 10(1):110-5. Lara PN, Moon J, Redman MW, Semrad TJ, Kelly K, Allen JW, Gitlitz BJ, Mack PC, Gandara DR. PMID: 25490004; PMCID: PMC4320001.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    26. Pharmacodynamic separation of gemcitabine and erlotinib in locally advanced or metastatic pancreatic cancer: therapeutic and biomarker results. Int J Clin Oncol. 2015 Jun; 20(3):518-24. Semrad T, Barzi A, Lenz HJ, Hutchins IM, Kim EJ, Gong IY, Tanaka M, Beckett L, Holland W, Burich RA, Snyder-Solis L, Mack P, Lara PN. PMID: 25091263; PMCID: PMC4318776.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    27. Phase I study of the combination of temsirolimus and pazopanib in advanced solid tumors. Anticancer Drugs. 2013 Jul; 24(6):636-40. Semrad TJ, Eddings C, Dutia MP, Christensen S, Lara PN. PMID: 23698253; PMCID: PMC4153755.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    28. Feasibility study of intra-patient sorafenib dose-escalation or re-escalation in patients with previously treated advanced solid tumors. Invest New Drugs. 2012 Oct; 30(5):2001-7. Semrad TJ, Eddings C, Pan CX, Lau DH, Gandara D, Beckett L, Lara PN. PMID: 22015991; PMCID: PMC4131984.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    29. Fibroblast growth factor signaling in non-small-cell lung cancer. Clin Lung Cancer. 2012 Mar; 13(2):90-5. Semrad TJ, Mack PC. PMID: 21959109.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    30. Enhancing the clinical activity of sorafenib through dose escalation: rationale and current experience. Ther Adv Med Oncol. 2011 Mar; 3(2):95-100. Semrad TJ, Gandara DR, Lara PN. PMID: 21789159; PMCID: PMC3126039.
      View in: PubMed   Mentions: 7  
    31. Geographic variation of racial/ethnic disparities in colorectal cancer testing among medicare enrollees. Cancer. 2011 Apr 15; 117(8):1755-63. Semrad TJ, Tancredi DJ, Baldwin LM, Green P, Fenton JJ. PMID: 21472723; PMCID: PMC4570926.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    32. Epidemiology of venous thromboembolism in 9489 patients with malignant glioma. J Neurosurg. 2007 Apr; 106(4):601-8. Semrad TJ, O'Donnell R, Wun T, Chew H, Harvey D, Zhou H, White RH. PMID: 17432710.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    33. Mutational analysis of immunoglobulin germline derived Vlambda4A light chains in rheumatoid arthritis. Clin Immunol. 2001 May; 99(2):276-82. Semrad TJ, Kenny TP, Malyj W, Robbins DL. PMID: 11318599.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    34. Mutational analysis of immunoglobulin germline derived Vlambda4B light chains in rheumatoid arthritis. Clin Immunol. 2001 May; 99(2):283-90. Kenny TP, Semrad TJ, Malyj W, Robbins DL. PMID: 11318600.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells