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Thomas W North

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InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. North T, Villalobos A, Hurwitz SJ, Deere JD, Higgins J, Chatterjee P, Tao S, Kauffman RC, Luciw PA, Kohler JJ, Schinazi RF. Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics. Antimicrob Agents Chemother. 2014 Jul; 58(7):3927-33. PMID: 24777106.
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    2. Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North T. Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART. PLoS One. 2014; 9(2):e87914. PMID: 24505331; PMCID: PMC3914874.
    3. Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North T. Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV. PLoS One. 2014; 9(1):e86997. PMID: 24498008; PMCID: PMC3909041.
    4. Gavegnano C, Detorio MA, Bassit L, Hurwitz SJ, North T, Schinazi RF. Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages. Antimicrob Agents Chemother. 2013 Mar; 57(3):1262-9. PMID: 23263005; PMCID: PMC3591918.
    5. Deere JD, Schinazi RF, North T. Simian immunodeficiency virus macaque models of HIV latency. Curr Opin HIV AIDS. 2011 Jan; 6(1):57-61. PMID: 21242894.
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    6. Deere JD, Higgins J, Cannavo E, Villalobos A, Adamson L, Fromentin E, Schinazi RF, Luciw PA, North T. Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS. PLoS One. 2010 Jul 23; 5(7):e11640. PMID: 20668516; PMCID: PMC2909142.
    7. North T, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. J Virol. 2010 Mar; 84(6):2913-22. PMID: 20032180; PMCID: PMC2826073.
    8. Van Rompay KK, Johnson JA, Blackwood EJ, Singh RP, Lipscomb J, Matthews TB, Marthas ML, Pedersen NC, Bischofberger N, Heneine W, North T. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. Retrovirology. 2007 Apr 06; 4:25. PMID: 17417971; PMCID: PMC1852805.
    9. Duong YT, Meadows DC, Srivastava IK, Gervay-Hague J, North T. Direct inactivation of human immunodeficiency virus type 1 by a novel small-molecule entry inhibitor, DCM205. Antimicrob Agents Chemother. 2007 May; 51(5):1780-6. PMID: 17307982; PMCID: PMC1855571.
    10. Meadows DC, Sanchez T, Neamati N, North T, Gervay-Hague J. Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1. Bioorg Med Chem. 2007 Jan 15; 15(2):1127-37. PMID: 17074494; PMCID: PMC1994090.
    11. Meadows DC, Mathews TB, North T, Hadd MJ, Kuo CL, Neamati N, Gervay-Hague J. Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors. J Med Chem. 2005 Jul 14; 48(14):4526-34. PMID: 15999991.
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    12. North T, Van Rompay KK, Higgins J, Matthews TB, Wadford DA, Pedersen NC, Schinazi RF. Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. J Virol. 2005 Jun; 79(12):7349-54. PMID: 15919889; PMCID: PMC1143671.
    13. Joshi PJ, North T, Prasad VR. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Mol Ther. 2005 May; 11(5):677-86. PMID: 15851006.
      View in: PubMed
    14. Hofman MJ, Higgins J, Matthews TB, Pedersen NC, Tan C, Schinazi RF, North T. Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2004 Sep; 48(9):3483-90. PMID: 15328115; PMCID: PMC514752.
    15. North T, Sequar G, Townsend LB, Drach JC, Barry PA. Rhesus cytomegalovirus is similar to human cytomegalovirus in susceptibility to benzimidazole nucleosides. Antimicrob Agents Chemother. 2004 Jul; 48(7):2760-5. PMID: 15215146; PMCID: PMC434194.
    16. Pedersen NC, North T, Rigg R, Reading C, Higgins J, Leutenegger C, Henderson GL. 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression. Vet Immunol Immunopathol. 2003 Aug 15; 94(3-4):133-48. PMID: 12909410.
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    17. Giuffre AC, Higgins J, Buckheit RW, North T. Susceptibilities of simian immunodeficiency virus to protease inhibitors. Antimicrob Agents Chemother. 2003 May; 47(5):1756-9. PMID: 12709355; PMCID: PMC153320.
    18. Murry JP, Higgins J, Matthews TB, Huang VY, Van Rompay KK, Pedersen NC, North T. Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine. J Virol. 2003 Jan; 77(2):1120-30. PMID: 12502828; PMCID: PMC140811.
    19. Klarmann GJ, Chen X, North T, Preston BD. Incorporation of uracil into minus strand DNA affects the specificity of plus strand synthesis initiation during lentiviral reverse transcription. J Biol Chem. 2003 Mar 07; 278(10):7902-9. PMID: 12458216.
      View in: PubMed
    20. Van Rompay KK, Matthews TB, Higgins J, Canfield DR, Tarara RP, Wainberg MA, Schinazi RF, Pedersen NC, North T. Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. J Virol. 2002 Jun; 76(12):6083-92. PMID: 12021341; PMCID: PMC136201.
    21. Auwerx J, North T, Preston BD, Klarmann GJ, De Clercq E, Balzarini J. Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors. Mol Pharmacol. 2002 Feb; 61(2):400-6. PMID: 11809865.
      View in: PubMed