Wenbin Deng

Title(s)Professor, Biochemistry and Molecular Medicine
SchoolUniversity of California, Davis
AddressShriners 653B
CA 95817
Phone916-453-2287
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    Collapse Research 
    Collapse Research Activities and Funding
    Differentiation and Integration of Trisomy 21 iPSCs in an Animal Model
    NIH R01HD091325Aug 1, 2017 - Apr 30, 2022
    Role: Co-Principal Investigator
    Regenerating CNS white matter using induced pluripotent stem cells
    NIH R01HD087566Mar 1, 2016 - Feb 28, 2021
    Role: Principal Investigator
    Glutamate Receptors in Hypoxic-ischemic Injury to Developing Oligodendrocytes
    NIH R01NS059043Apr 1, 2008 - Mar 31, 2014
    Role: Principal Investigator
    Oligodendrocytes, Glutamate Receptors, and Lead Neurotoxicity
    NIH R01ES015988Aug 22, 2007 - May 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Black phosphorus nanosheets-based stable drug delivery system via drug-self-stabilization for combined photothermal and chemo cancer therapy. Chemical Engineering Journal. 2019 Nov 1; 375:121917. Liu LG, Tsai TH, Zeng ZX, Qi QJ, Luo LM, Wang WX, Mei ML, Deng DW. .
      View in: Publisher Site   Mentions:
    2. Polydopamine-Based "Four-in-One" Versatile Nanoplatforms for Targeted Dual Chemo and Photothermal Synergistic Cancer Therapy. Pharmaceutics. 2019 Oct 01; 11(10). Liu G, Gao N, Zhou Y, Nie J, Cheng W, Luo M, Mei L, Zeng X, Deng W. PMID: 31581532; PMCID: PMC6835447.
      View in: PubMed   Mentions: 15  
    3. Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro. Stem Cell Res Ther. 2019 08 27; 10(1):272. Namchaiw P, Wen H, Mayrhofer F, Chechneva O, Biswas S, Deng W. PMID: 31455382; PMCID: PMC6712625.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    4. Expression analysis of Argonaute genes in maize (Zea mays L.) in response to abiotic stress. Hereditas. 2019; 156:27. Zhai L, Teng F, Zheng K, Xiao J, Deng W, Sun W. PMID: 31367213; PMCID: PMC6651970.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    5. Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo. Sci Rep. 2019 06 21; 9(1):9013. Biswas S, Chung SH, Jiang P, Dehghan S, Deng W. PMID: 31227736; PMCID: PMC6588721.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    6. Folic Acid-Functionalized Black Phosphorus Quantum Dots for Targeted Chemo-Photothermal Combination Cancer Therapy. Pharmaceutics. 2019 May 21; 11(5). Luo M, Cheng W, Zeng X, Mei L, Liu G, Deng W. PMID: 31117238; PMCID: PMC6571808.
      View in: PubMed   Mentions: 13  
    7. Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro. ACS Appl Mater Interfaces. 2019 Feb 13; 11(6):5821-5833. Wen H, Xiao W, Biswas S, Cong ZQ, Liu XM, Lam KS, Liao YH, Deng W. PMID: 30645095.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    8. Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure. Sci Rep. 2018 11 01; 8(1):16213. Thai PN, Daugherty DJ, Frederich BJ, Lu X, Deng W, Bers DM, Dedkova EN, Schaefer S. PMID: 30385779; PMCID: PMC6212397.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    9. In vivo conversion of astrocytes into oligodendrocyte lineage cells with transcription factor Sox10; Promise for myelin repair in multiple sclerosis. PLoS One. 2018; 13(9):e0203785. Mokhtarzadeh Khanghahi A, Satarian L, Deng W, Baharvand H, Javan M. PMID: 30212518; PMCID: PMC6136770.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    10. Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Cell Rep. 2018 07 10; 24(2):355-365. Mizuno GO, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, Broussard GJ, Unger EK, Deng W, Weick J, Bhattacharyya A, Chen CY, Yu G, Looger LL, Tian L. PMID: 29996097; PMCID: PMC6631348.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    11. The p38α MAPK Deletion in Oligodendroglia does not Attenuate Myelination Defects in a Mouse Model of Periventricular Leukomalacia. Neuroscience. 2018 08 21; 386:175-181. Chung SH, Biswas S, Sohn J, Jiang P, Dehghan S, Marzban H, Deng W. PMID: 29966722; PMCID: PMC6076863.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. Textile-supported silver nanoparticles as a highly efficient and recyclable heterogeneous catalyst for nitroaromatic reduction at room temperature. RSC Advances. 2018 Jan 1; 8(12):6288-6292. Feng FW, Huang HT, Gao GL, Yang YX, Deng DW, Zhou ZR, Liu LH. .
      View in: Publisher Site   Mentions:
    13. Serum Response Factor Promotes Dopaminergic Neuron Survival via Activation of Beclin 1-Dependent Autophagy. Neuroscience. 2018 02 10; 371:288-295. Cheng XY, Li SY, Mao CJ, Wang MX, Chen J, Wang F, Wang GH, Deng WB, Li XK, Liu CF. PMID: 29196028.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. Methods of reactivation and reprogramming of neural stem cells for neural repair. Methods. 2018 01 15; 133:3-20. Tian Z, Zhao Q, Biswas S, Deng W. PMID: 28864354.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. Neural Stem Cell-Based Regenerative Approaches for the Treatment of Multiple Sclerosis. Mol Neurobiol. 2018 Apr; 55(4):3152-3171. Xiao J, Yang R, Biswas S, Zhu Y, Qin X, Zhang M, Zhai L, Luo Y, He X, Mao C, Deng W. PMID: 28466274; PMCID: PMC5668198.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    16. The Crystal Structure of Monovalent Streptavidin. Sci Rep. 2016 12 21; 6:35915. Zhang M, Biswas S, Deng W, Yu H. PMID: 28000673; PMCID: PMC5175265.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    17. Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. Stem Cells. 2016 11; 34(11):2670-2680. Yechikov S, Copaciu R, Gluck JM, Deng W, Chiamvimonvat N, Chan JW, Lieu DK. PMID: 27434649; PMCID: PMC5798452.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. Mitochondrial translocator protein (TSPO), astrocytes and neuroinflammation. Neural Regen Res. 2016 Jul; 11(7):1056-7. Chechneva OV, Deng W. PMID: 27630677; PMCID: PMC4994436.
      View in: PubMed   Mentions: 8  
    19. Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? Cancer Med. 2016 08; 5(8):2048-60. Zhang M, Biswas S, Qin X, Gong W, Deng W, Yu H. PMID: 27228302; PMCID: PMC4884632.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    20. Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion. Cell Rep. 2016 05 10; 15(6):1303-15. Jiang P, Chen C, Liu XB, Pleasure DE, Liu Y, Deng W. PMID: 27134175; PMCID: PMC4864503.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    21. Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells. Int J Mol Sci. 2016 Apr 20; 17(4). Tian Z, Guo F, Biswas S, Deng W. PMID: 27104529; PMCID: PMC4849048.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    22. The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. Sci Rep. 2016 Mar 01; 6:22556. Daugherty DJ, Chechneva O, Mayrhofer F, Deng W. PMID: 26925573; PMCID: PMC4772008.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    23. Argonaute and Argonaute-Bound Small RNAs in Stem Cells. Int J Mol Sci. 2016 Feb 04; 17(2):208. Zhai L, Wang L, Teng F, Zhou L, Zhang W, Xiao J, Liu Y, Deng W. PMID: 26861290; PMCID: PMC4783940.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. The vulnerability of thalamocortical circuitry to hypoxic-ischemic injury in a mouse model of periventricular leukomalacia. BMC Neurosci. 2016 Jan 05; 17:2. Liu XB, Shen Y, Pleasure DE, Deng W. PMID: 26733225; PMCID: PMC4702373.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    25. Human Induced Pluripotent Stem Cell NEUROG2 Dual Knockin Reporter Lines Generated by the CRISPR/Cas9 System. Stem Cells Dev. 2015 Dec 15; 24(24):2925-42. Li S, Xue H, Wu J, Rao MS, Kim DH, Deng W, Liu Y. PMID: 26414932; PMCID: PMC4683556.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    26. Stem and Progenitor Cell-Derived Astroglia Therapies for Neurological Diseases. Trends Mol Med. 2015 Nov; 21(11):715-729. Chen C, Chan A, Wen H, Chung SH, Deng W, Jiang P. PMID: 26443123; PMCID: PMC4637244.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    27. Reverse engineering human neurodegenerative disease using pluripotent stem cell technology. Brain Res. 2016 May 01; 1638(Pt A):30-41. Liu Y, Deng W. PMID: 26423934; PMCID: PMC4809784.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    28. Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. J Neuroinflammation. 2015 Jun 12; 12:117. Xiao J, Liu W, Chen Y, Deng W. PMID: 26068104; PMCID: PMC4474568.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    29. A novel approach to make homogeneous protease-stable monovalent streptavidin. Biochem Biophys Res Commun. 2015 Aug 07; 463(4):1059-63. Zhang M, Shao J, Xiao J, Deng W, Yu H. PMID: 26074145; PMCID: PMC4498676.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    30. The p38a mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS. Cell Death Dis. 2015 May 07; 6:e1748. Chung SH, Biswas S, Selvaraj V, Liu XB, Sohn J, Jiang P, Chen C, Chmilewsky F, Marzban H, Horiuchi M, Pleasure DE, Deng W. PMID: 25950478; PMCID: PMC4669698.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    31. Mesenchymal stem cells and induced pluripotent stem cells as therapies for multiple sclerosis. Int J Mol Sci. 2015 Apr 24; 16(5):9283-302. Xiao J, Yang R, Biswas S, Qin X, Zhang M, Deng W. PMID: 25918935; PMCID: PMC4463588.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    32. The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/�-catenin signaling. J Neurosci. 2015 Mar 25; 35(12):5007-22. Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. PMID: 25810530; PMCID: PMC6705374.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    33. Kirenol attenuates experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and th17 cells and inducing apoptosis of effector T cells. Sci Rep. 2015 Mar 12; 5:9022. Xiao J, Yang R, Yang L, Fan X, Liu W, Deng W. PMID: 25762107; PMCID: PMC4356981.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    34. The subventricular zone continues to generate corpus callosum and rostral migratory stream astroglia in normal adult mice. J Neurosci. 2015 Mar 04; 35(9):3756-63. Sohn J, Orosco L, Guo F, Chung SH, Bannerman P, Mills Ko E, Zarbalis K, Deng W, Pleasure D. PMID: 25740506; PMCID: PMC6605576.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    35. Empowering sonic hedgehog to rescue brain cells after ischemic stroke. Neural Regen Res. 2015 Mar; 10(3):360-2. Chechneva OV, Deng W. PMID: 25878576; PMCID: PMC4396090.
      View in: PubMed   Mentions: 7  
    36. The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. Front Oncol. 2014; 4:357. Qin X, Xu H, Gong W, Deng W. PMID: 25601903; PMCID: PMC4283433.
      View in: PubMed   Mentions: 26  
    37. p38a (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes. Sci Rep. 2014 Dec 12; 4:7405. Lo U, Selvaraj V, Plane JM, Chechneva OV, Otsu K, Deng W. PMID: 25502009; PMCID: PMC4264013.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    38. A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury. Cell Death Dis. 2014 Oct 23; 5:e1481. Chechneva OV, Mayrhofer F, Daugherty DJ, Krishnamurty RG, Bannerman P, Pleasure DE, Deng W. PMID: 25341035; PMCID: PMC4649529.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    39. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nat Commun. 2014 Jul 18; 5:4430. Chen C, Jiang P, Xue H, Peterson SE, Tran HT, McCann AE, Parast MM, Li S, Pleasure DE, Laurent LC, Loring JF, Liu Y, Deng W. PMID: 25034944; PMCID: PMC4109022.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    40. Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology. 2014 Jan; 155(1):89-97. Morohaku K, Pelton SH, Daugherty DJ, Butler WR, Deng W, Selvaraj V. PMID: 24174323; PMCID: PMC3868810.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    41. Generation and characterization of spiking and nonspiking oligodendroglial progenitor cells from embryonic stem cells. Stem Cells. 2013 Dec; 31(12):2620-31. Jiang P, Chen C, Liu XB, Selvaraj V, Liu W, Feldman DH, Liu Y, Pleasure DE, Li RA, Deng W. PMID: 23940003; PMCID: PMC3923867.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    42. Stimuli-responsive cross-linked micelles for on-demand drug delivery against cancers. Adv Drug Deliv Rev. 2014 Feb; 66:58-73. Li Y, Xiao K, Zhu W, Deng W, Lam KS. PMID: 24060922; PMCID: PMC3947689.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    43. A TSPO ligand is protective in a mouse model of multiple sclerosis. EMBO Mol Med. 2013 Jun; 5(6):891-903. Daugherty DJ, Selvaraj V, Chechneva OV, Liu XB, Pleasure DE, Deng W. PMID: 23681668; PMCID: PMC3779450.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    44. Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. Cell Death Dis. 2013 Mar 14; 4:e546. Chung SH, Guo F, Jiang P, Pleasure DE, Deng W. PMID: 23492777; PMCID: PMC3615735.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    45. Vulnerability of premyelinating oligodendrocytes to white-matter damage in neonatal brain injury. Neurosci Bull. 2013 Apr; 29(2):229-38. Liu XB, Shen Y, Plane JM, Deng W. PMID: 23456565; PMCID: PMC5561874.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    46. Stem cell models for drug discovery and toxicology studies. J Biochem Mol Toxicol. 2013 Jan; 27(1):17-27. Liu W, Deng Y, Liu Y, Gong W, Deng W. PMID: 23293059.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    47. hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nat Commun. 2013; 4:2196. Jiang P, Chen C, Wang R, Chechneva OV, Chung SH, Rao MS, Pleasure DE, Liu Y, Zhang Q, Deng W. PMID: 23880652; PMCID: PMC3903179.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    48. PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum. J Neurosci. 2012 Aug 29; 32(35):12152-64. Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. PMID: 22933798; PMCID: PMC3457640.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    49. Oligodendrocyte progenitor cells derived from mouse embryonic stem cells give rise to type-1 and type-2 astrocytes in vitro. Neurosci Lett. 2012 Aug 15; 523(2):180-5. Chen C, Daugherty D, Jiang P, Deng W. PMID: 22781495; PMCID: PMC3417135.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    50. PARP-1 deletion promotes subventricular zone neural stem cells toward a glial fate. J Neurosci Res. 2012 Aug; 90(8):1489-506. Plane JM, Grossenbacher SK, Deng W. PMID: 22431411; PMCID: PMC3370105.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    51. Differentiating human stem cells into neurons and glial cells for neural repair. Front Biosci (Landmark Ed). 2012 01 01; 17(1):65-89. Selvaraj V, Jiang P, Chechneva O, Lo UG, Deng W. PMID: 22201733.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    52. Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. Neuron Glia Biol. 2010 Nov; 6(4):277-88. Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE. PMID: 22169210; PMCID: PMC6732218.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    53. DNA polymerase-� mediates the neurogenic effect of �-amyloid protein in cultured subventricular zone neurospheres. J Neurosci Res. 2012 Mar; 90(3):559-67. Calafiore M, Copani A, Deng W. PMID: 22057776; PMCID: PMC3259249.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    54. Electrically guiding migration of human induced pluripotent stem cells. Stem Cell Rev Rep. 2011 Nov; 7(4):987-96. Zhang J, Calafiore M, Zeng Q, Zhang X, Huang Y, Li RA, Deng W, Zhao M. PMID: 21373881; PMCID: PMC3226697.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    55. Axon-glia synapses are highly vulnerable to white matter injury in the developing brain. J Neurosci Res. 2012 Jan; 90(1):105-21. Shen Y, Liu XB, Pleasure DE, Deng W. PMID: 21812016; PMCID: PMC3209489.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    56. Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cord. Neurobiol Dis. 2011 Oct; 44(1):63-72. Chechneva OV, Mayrhofer F, Daugherty DJ, Pleasure DE, Hong JS, Deng W. PMID: 21704706; PMCID: PMC3153572.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    57. Zfp488 promotes oligodendrocyte differentiation of neural progenitor cells in adult mice after demyelination. Sci Rep. 2011; 1:2. Soundarapandian MM, Selvaraj V, Lo UG, Golub MS, Feldman DH, Pleasure DE, Deng W. PMID: 22355521; PMCID: PMC3210692.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    58. Label-free detection of surface markers on stem cells by oblique-incidence reflectivity difference microscopy. Biotechniques. 2011 Jun; 50(6):381-8. Lo KY, Sun YS, Landry JP, Zhu X, Deng W. PMID: 21781038; PMCID: PMC3271734.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    59. Concise review: Quiescent and active states of endogenous adult neural stem cells: identification and characterization. Stem Cells. 2011 Jun; 29(6):907-12. Wang YZ, Plane JM, Jiang P, Zhou CJ, Deng W. PMID: 21557389; PMCID: PMC3306660.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    60. Neuroprotective potential of erythropoietin and its derivative carbamylated erythropoietin in periventricular leukomalacia. Exp Neurol. 2011 Aug; 230(2):227-39. Liu W, Shen Y, Plane JM, Pleasure DE, Deng W. PMID: 21596035; PMCID: PMC3114206.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    61. OLIG gene targeting in human pluripotent stem cells for motor neuron and oligodendrocyte differentiation. Nat Protoc. 2011 May; 6(5):640-55. Liu Y, Jiang P, Deng W. PMID: 21527921.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    62. Apoptosis inducing factor deficiency causes reduced mitofusion 1 expression and patterned Purkinje cell degeneration. Neurobiol Dis. 2011 Feb; 41(2):445-57. Chung SH, Calafiore M, Plane JM, Pleasure DE, Deng W. PMID: 20974255; PMCID: PMC3014456.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    63. Prospects for minocycline neuroprotection. Arch Neurol. 2010 Dec; 67(12):1442-8. Plane JM, Shen Y, Pleasure DE, Deng W. PMID: 20697034; PMCID: PMC3127230.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    64. Exploiting pluripotency for therapeutic gain. Panminerva Med. 2010 Jun; 52(2):167-73. Deng W. PMID: 20517198.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    65. Differentiation of embryonic stem cells into oligodendrocyte precursors. J Vis Exp. 2010 May 19; (39). Jiang P, Selvaraj V, Deng W. PMID: 20489683; PMCID: PMC3149995.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    66. Mouse models of periventricular leukomalacia. J Vis Exp. 2010 May 18; (39). Shen Y, Plane JM, Deng W. PMID: 20485263; PMCID: PMC3149994.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    67. Neurobiology of injury to the developing brain. Nat Rev Neurol. 2010 Jun; 6(6):328-36. Deng W. PMID: 20479779.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    68. AID in reprogramming: quick and efficient: identification of a key enzyme called AID, and its activity in DNA demethylation, may help to overcome a pivotal epigenetic barrier in reprogramming somatic cells toward pluripotency. Bioessays. 2010 May; 32(5):385-7. Deng W. PMID: 20394066.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    69. Blood-brain barrier breakdown and repair by Src after thrombin-induced injury. Ann Neurol. 2010 Apr; 67(4):526-33. Liu DZ, Ander BP, Xu H, Shen Y, Kaur P, Deng W, Sharp FR. PMID: 20437588; PMCID: PMC2919346.
      View in: PubMed   Mentions: 91     Fields:    Translation:Animals
    70. Induced pluripotent stem cells: paths to new medicines. A catalyst for disease modelling, drug discovery and regenerative therapy. EMBO Rep. 2010 Mar; 11(3):161-5. Deng W. PMID: 20168328; PMCID: PMC2838691.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    71. Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies. Trends Biotechnol. 2010 Apr; 28(4):214-23. Selvaraj V, Plane JM, Williams AJ, Deng W. PMID: 20149468; PMCID: PMC2843790.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    72. Electrophysiological properties of human induced pluripotent stem cells. Am J Physiol Cell Physiol. 2010 Mar; 298(3):C486-95. Jiang P, Rushing SN, Kong CW, Fu J, Lieu DK, Chan CW, Deng W, Li RA. PMID: 19955484; PMCID: PMC2838581.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    73. Genome integrity: linking pluripotency and tumorgenicity. Trends Genet. 2009 Oct; 25(10):425-7. Deng W, Xu Y. PMID: 19801173; PMCID: PMC2789921.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    74. PARylation: strengthening the connection between cancer and pluripotency. Cell Stem Cell. 2009 Oct 02; 5(4):349-50. Deng W. PMID: 19796612.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    75. PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis. J Biol Chem. 2009 Sep 18; 284(38):26070-84. Selvaraj V, Soundarapandian MM, Chechneva O, Williams AJ, Sidorov MK, Soulika AM, Pleasure DE, Deng W. PMID: 19628872; PMCID: PMC2758007.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    76. Progress in periventricular leukomalacia. Arch Neurol. 2008 Oct; 65(10):1291-5. Deng W, Pleasure J, Pleasure D. PMID: 18852342; PMCID: PMC2898886.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    77. Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit composition and cAMP-response element-binding protein regulate oligodendrocyte excitotoxicity. J Biol Chem. 2006 Nov 24; 281(47):36004-11. Deng W, Neve RL, Rosenberg PA, Volpe JJ, Jensen FE. PMID: 16990276.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    78. Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function. J Neurochem. 2006 Jul; 98(1):213-22. Deng W, Yue Q, Rosenberg PA, Volpe JJ, Jensen FE. PMID: 16606353.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    79. Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7751-6. Deng W, Wang H, Rosenberg PA, Volpe JJ, Jensen FE. PMID: 15136737; PMCID: PMC419678.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    80. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci. 2004 May 05; 24(18):4412-20. Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, Volpe JJ, Jensen FE. PMID: 15128855; PMCID: PMC6729451.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    81. Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6801-6. Deng W, Rosenberg PA, Volpe JJ, Jensen FE. PMID: 12743362; PMCID: PMC164527.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    82. Oligodendroglia in developmental neurotoxicity. Neurotoxicology. 2003 Mar; 24(2):161-78. Deng W, Poretz RD. PMID: 12606289.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    83. Protein kinase C activation is required for the lead-induced inhibition of proliferation and differentiation of cultured oligodendroglial progenitor cells. Brain Res. 2002 Mar 01; 929(1):87-95. Deng W, Poretz RD. PMID: 11852034.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    84. Lead alters the developmental profile of the galactolipid metabolic enzymes in cultured oligodendrocyte lineage cells. Neurotoxicology. 2001 Aug; 22(4):429-37. Deng W, Poretz RD. PMID: 11577801.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    85. Lead exposure delays the differentiation of oligodendroglial progenitors in vitro. Toxicol Appl Pharmacol. 2001 Aug 01; 174(3):235-44. Deng W, McKinnon RD, Poretz RD. PMID: 11485384.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    86. Lead exposure affects levels of galactolipid metabolic enzymes in the developing rat brain. Toxicol Appl Pharmacol. 2001 Apr 15; 172(2):98-107. Deng W, Poretz RD. PMID: 11298496.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    87. The interaction of lead exposure and arylsulfatase A genotype affects sulfatide catabolism in human fibroblasts. Neurotoxicology. 2000 Jun; 21(3):379-87. Poretz RD, Yang A, Deng W, Manowitz P. PMID: 10894127.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
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