Leonard Hjelmeland

Title(s)Professor Emeritus, MED: Eye Center
SchoolSchool of Medicine
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    1. Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide. J Ophthalmol. 2016; 2016:9856736. Smit-McBride Z, Moisseiev E, Modjtahedi SP, Telander DG, Hjelmeland LM, Morse LS. PMID: 27429799; PMCID: PMC4939337.
      View in: PubMed   Mentions: 3  
    2. GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration. Curr Eye Res. 2016; 41(3):410-6. Hunter AA, Smit-McBride Z, Anderson R, Bordbari MH, Ying GS, Kim ES, Park SS, Telander DG, Dunaief JL, Hjelmeland LM, Morse LS. PMID: 25897651; PMCID: PMC4972491.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    3. Localization of complement factor H gene expression and protein distribution in the mouse outer retina. Mol Vis. 2015; 21:110-23. Smit-McBride Z, Oltjen SL, Radu RA, Estep J, Nguyen AT, Gong Q, Hjelmeland LM. PMID: 25684976; PMCID: PMC4323684.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    4. Age-dependent increase in miRNA-34a expression in the posterior pole of the mouse eye. Mol Vis. 2014; 20:1569-78. Smit-McBride Z, Forward KI, Nguyen AT, Bordbari MH, Oltjen SL, Hjelmeland LM. PMID: 25489229; PMCID: PMC4225137.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    5. In vivo gene expression profiling of retina postintravitreal injections of dexamethasone and triamcinolone at clinically relevant time points for patient care. Invest Ophthalmol Vis Sci. 2011 Nov 21; 52(12):8965-78. Smit-McBride Z, Modjtahedi SP, Cessna CT, Telander DG, Hjelmeland LM, Morse LS. PMID: 21873667.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    6. Dark matters in AMD genetics: epigenetics and stochasticity. Invest Ophthalmol Vis Sci. 2011 Mar; 52(3):1622-31. Hjelmeland LM. PMID: 21429863; PMCID: PMC3101660.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    7. Quantification of retinal pigment epithelial phenotypic variation using laser scanning cytometry. Mol Vis. 2010 Jun 16; 16:1108-21. Hjelmeland LM, Fujikawa A, Oltjen SL, Smit-McBride Z, Braunschweig D. PMID: 20606706; PMCID: PMC2893051.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    8. A strong genetic determinant of hyperoxia-related retinal degeneration on mouse chromosome 6. Invest Ophthalmol Vis Sci. 2007 Jan; 48(1):405-11. Smit-McBride Z, Oltjen SL, Lavail MM, Hjelmeland LM. PMID: 17197561.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    9. Regulation of cysteine cathepsin expression by oxidative stress in the retinal pigment epithelium/choroid of the mouse. Exp Eye Res. 2006 Sep; 83(3):679-87. Alizadeh P, Smit-McBride Z, Oltjen SL, Hjelmeland LM. PMID: 16684524; PMCID: PMC1661778.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    10. The expression of native and cultured human retinal pigment epithelial cells grown in different culture conditions. Br J Ophthalmol. 2005 Nov; 89(11):1510-7. Tian J, Ishibashi K, Honda S, Boylan SA, Hjelmeland LM, Handa JT. PMID: 16234463; PMCID: PMC1772910.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    11. Mosaicism of the retinal pigment epithelium: seeing the small picture. Mol Interv. 2005 Aug; 5(4):241-9. Burke JM, Hjelmeland LM. PMID: 16123538.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    12. Changes in the spatial expression of genes with aging in the mouse RPE/choroid. Mol Vis. 2005 Jun 01; 11:380-6. Ogawa T, Boylan SA, Oltjen SL, Hjelmeland LM. PMID: 15947738.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    13. EST analysis of mouse retina and RPE/choroid cDNA libraries. Mol Vis. 2004 Jul 06; 10:439-44. Ida H, Boylan SA, Weigel AL, Smit-McBride Z, Chao A, Gao J, Buchoff P, Wistow G, Hjelmeland LM. PMID: 15257269.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    14. Ultrastructural aging of the RPE-Bruch's membrane-choriocapillaris complex in the D-galactose-treated mouse. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2348-54. Ida H, Ishibashi K, Reiser K, Hjelmeland LM, Handa JT. PMID: 15223816.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    15. Topographic and age-dependent expression of heme oxygenase-1 and catalase in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2004 May; 45(5):1562-5. Miyamura N, Ogawa T, Boylan S, Morse LS, Handa JT, Hjelmeland LM. PMID: 15111615.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. Age-related changes in the transcriptional profile of mouse RPE/choroid. Physiol Genomics. 2003 Nov 11; 15(3):258-62. Ida H, Boylan SA, Weigel AL, Hjelmeland LM. PMID: 14519767.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    17. Acute hyperoxia-induced transcriptional response in the mouse RPE/choroid. Free Radic Biol Med. 2003 Sep 01; 35(5):465-74. Weigel AL, Ida H, Boylan SA, Hjelmeland LM. PMID: 12927596.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    18. Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells. Invest Ophthalmol Vis Sci. 2003 Apr; 44(4):1716-21. Philp NJ, Wang D, Yoon H, Hjelmeland LM. PMID: 12657613.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    19. Human RPE cells express the FGFR2IIIc and FGFR3IIIc splice variants and FGF9 as a potential high affinity ligand. Exp Eye Res. 2003 Feb; 76(2):249-56. Alizadeh M, Miyamura N, Handa JT, Hjelmeland LM. PMID: 12565813.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Microarray analysis of H2O2-, HNE-, or tBH-treated ARPE-19 cells. Free Radic Biol Med. 2002 Nov 15; 33(10):1419-32. Weigel AL, Handa JT, Hjelmeland LM. PMID: 12419474.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    21. Senescence associated beta galactosidase activity in human retinal pigment epithelial cells exposed to mild hyperoxia in vitro. Br J Ophthalmol. 2002 Feb; 86(2):159-62. Honda S, Hjelmeland LM, Handa JT. PMID: 11815340; PMCID: PMC1771010.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    22. Downregulation of differentiation specific gene expression by oxidative stress in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2001 Oct; 42(11):2706-13. Alizadeh M, Wada M, Gelfman CM, Handa JT, Hjelmeland LM. PMID: 11581219.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    23. Density-dependent expression of FGF-2 in response to oxidative stress in RPE cells in vitro. Curr Eye Res. 2001 Sep; 23(3):226-31. Wada M, Gelfman CM, Matsunaga H, Alizadeh M, Morse L, Handa JT, Hjelmeland LM. PMID: 11803485.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Induction of an aging mRNA retinal pigment epithelial cell phenotype by matrix-containing advanced glycation end products in vitro. Invest Ophthalmol Vis Sci. 2001 Sep; 42(10):2419-25. Honda S, Farboud B, Hjelmeland LM, Handa JT. PMID: 11527959.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    25. An optimized protocol for first strand cDNA synthesis from laser capture microdissected tissue. Lab Invest. 2001 Aug; 81(8):1167-9. Boylan S, Honda S, Hjelmeland LM, Handa JT. PMID: 11502868.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Oxidative stress--induced single-strand breaks in chromosomal telomeres of human retinal pigment epithelial cells in vitro. Invest Ophthalmol Vis Sci. 2001 Aug; 42(9):2139-44. Honda S, Hjelmeland LM, Handa JT. PMID: 11481283.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    27. Age and topographic variation of insulin-like growth factor-binding protein 2 in the human rpe. Invest Ophthalmol Vis Sci. 2001 Jun; 42(7):1626-30. Miyamura N, Mishima K, Honda S, Aotaki-Keen AE, Morse LS, Handa JT, Hjelmeland LM. PMID: 11381070.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Induction of telomere shortening and replicative senescence by cryopreservation. Biochem Biophys Res Commun. 2001 Mar 30; 282(2):493-8. Honda S, Weigel A, Hjelmeland LM, Handa JT. PMID: 11401486.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    29. The use of hyperoxia to induce chronic mild oxidative stress in RPE cells in vitro. Mol Vis. 2001 Mar 14; 7:63-70. Honda S, Hjelmeland LM, Handa JT. PMID: 11249881.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    30. Expression of a recombinant human RGR opsin in Lentivirus-transduced cultured cells. Mol Vis. 2000 Nov 18; 6:237-42. Yang M, Wang XG, Stout JT, Chen P, Hjelmeland LM, Appukuttan B, Fong HK. PMID: 11086144.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    31. Expression and splicing of FGF receptor mRNAs during APRE-19 cell differentiation in vitro. Invest Ophthalmol Vis Sci. 2000 Jul; 41(8):2357-62. Alizadeh M, Gelfman CM, Bench SR, Hjelmeland LM. PMID: 10892884.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    32. The mRNA phenotype of a human RPE cell line at replicative senescence. Mol Vis. 1999 Dec 29; 5:39. Matsunaga H, Handa JT, Gelfman CM, Hjelmeland LM. PMID: 10617776.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    33. Senescence of the retinal pigment epithelium. Mol Vis. 1999 Nov 03; 5:33. Hjelmeland LM, Cristofolo VJ, Funk W, Rakoczy E, Katz ML. PMID: 10562657.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    34. Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye. Mol Vis. 1999 Jul 14; 5:11. Farboud B, Aotaki-Keen A, Miyata T, Hjelmeland LM, Handa JT. PMID: 10407062.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    35. Angiogenic factors in human proliferative sickle cell retinopathy. Br J Ophthalmol. 1999 Jul; 83(7):838-46. Cao J, Mathews MK, McLeod DS, Merges C, Hjelmeland LM, Lutty GA. PMID: 10381672; PMCID: PMC1723129.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    36. Senescence-associated beta-galactosidase histochemistry for the primate eye. Invest Ophthalmol Vis Sci. 1999 Jun; 40(7):1590-3. Mishima K, Handa JT, Aotaki-Keen A, Lutty GA, Morse LS, Hjelmeland LM. PMID: 10359342.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    37. Increase in the advanced glycation end product pentosidine in Bruch's membrane with age. Invest Ophthalmol Vis Sci. 1999 Mar; 40(3):775-9. Handa JT, Verzijl N, Matsunaga H, Aotaki-Keen A, Lutty GA, te Koppele JM, Miyata T, Hjelmeland LM. PMID: 10067983.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    38. Senescence of the retinal pigmented epithelium. Invest Ophthalmol Vis Sci. 1999 Jan; 40(1):1-2. Hjelmeland LM. PMID: 9888419.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    39. Beta-galactosidase histochemistry and telomere loss in senescent retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1999 Jan; 40(1):197-202. Matsunaga H, Handa JT, Aotaki-Keen A, Sherwood SW, West MD, Hjelmeland LM. PMID: 9888444.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    40. Use of the ARPE-19 cell line as a model of RPE polarity: basolateral secretion of FGF5. Invest Ophthalmol Vis Sci. 1998 Dec; 39(13):2744-9. Dunn KC, Marmorstein AD, Bonilha VL, Rodriguez-Boulan E, Giordano F, Hjelmeland LM. PMID: 9856785.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    41. Differentiation of retinal pigment epithelial cells in vitro uncovers silencer activity in the FGF-5 gene promoter. Exp Eye Res. 1998 Aug; 67(2):151-62. Gelfman CM, Kelleher CM, Hjelmeland LM. PMID: 9733582.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    42. Histologic localization of indocyanine green dye in aging primate and human ocular tissues with clinical angiographic correlation. Ophthalmology. 1998 Jun; 105(6):1060-8. Chang AA, Morse LS, Handa JT, Morales RB, Tucker R, Hjelmeland L, Yannuzzi LA. PMID: 9627657.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    43. The advanced glycation endproduct pentosidine induces the expression of PDGF-B in human retinal pigment epithelial cells. Exp Eye Res. 1998 Apr; 66(4):411-9. Handa JT, Reiser KM, Matsunaga H, Hjelmeland LM. PMID: 9593635.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    44. Vascular endothelial growth factor and fibroblast growth factor 5 are colocalized in vascular and avascular epiretinal membranes. Am J Ophthalmol. 1997 Oct; 124(4):447-54. Schneeberger SA, Hjelmeland LM, Tucker RP, Morse LS. PMID: 9323936.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Expression of fibroblast growth factor-5 by bovine choroidal endothelial cells in vitro. Invest Ophthalmol Vis Sci. 1997 Sep; 38(10):2073-80. Keithahn MA, Aotaki-Keen AE, Schneeberger SA, Hjelmeland LM, Morse LS. PMID: 9331271.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    46. Expression of FGF5 in choroidal neovascular membranes associated with ARMD. Curr Eye Res. 1997 Apr; 16(4):396-9. Kitaoka T, Morse LS, Schneeberger S, Ishigooka H, Hjelmeland LM. PMID: 9134330.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    47. Apolipoprotein E in the subretinal fluid of rhegmatogenous and exudative retinal detachments. Retina. 1997; 17(1):38-43. Schneeberger SA, Iwahashi CK, Hjelmeland LM, Davis PA, Morse LS. PMID: 9051841.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Fibrinolysis of experimental subretinal haemorrhage without removal using tissue plasminogen activator. Br J Ophthalmol. 1996 Jul; 80(7):658-62. Morse LS, Benner JD, Hjelmeland LM, Landers MB. PMID: 8795382; PMCID: PMC505564.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    49. Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor. J Neurosci. 1996 Mar 01; 16(5):1679-88. Campochiaro PA, Chang M, Ohsato M, Vinores SA, Nie Z, Hjelmeland L, Mansukhani A, Basilico C, Zack DJ. PMID: 8774436; PMCID: PMC6578679.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    50. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996 Feb; 62(2):155-69. Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. PMID: 8698076.
      View in: PubMed   Mentions: 552     Fields:    Translation:HumansCells
    51. Trace element status and free radical defense in elderly rhesus macaques (Macaca mulatta) with macular drusen. Proc Soc Exp Biol Med. 1995 Apr; 208(4):370-7. Olin KL, Morse LS, Murphy C, Paul-Murphy J, Line S, Bellhorn RW, Hjelmeland LM, Keen CL. PMID: 7700885.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    52. Astrogliosis in culture. IV. Effects of basic fibroblast growth factor. J Neurosci Res. 1995 Feb 15; 40(3):359-70. Hou YJ, Yu AC, Garcia JM, Aotaki-Keen A, Lee YL, Eng LF, Hjelmeland LJ, Menon VK. PMID: 7745630.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    53. Comparison of techniques for transscleral diode photocoagulation in the rabbit. Retina. 1995; 15(3):253-60. Benner JD, Galustian JC, Lim M, Hjelmeland L, Landers MB, Morse LS. PMID: 7569354.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    54. Low glutathione reductase and peroxidase activity in age-related macular degeneration. Br J Ophthalmol. 1994 Oct; 78(10):791-4. Cohen SM, Olin KL, Feuer WJ, Hjelmeland L, Keen CL, Morse LS. PMID: 7803358; PMCID: PMC504938.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    55. Distribution of FGF-5 in the rhesus macaque retina. Invest Ophthalmol Vis Sci. 1994 Jul; 35(8):3189-98. Kitaoka T, Aotaki-Keen AE, Hjelmeland LM. PMID: 8045713.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    56. Expression of the MAS proto-oncogene in the retinal pigment epithelium of the rhesus macaque. Curr Eye Res. 1994 May; 13(5):345-51. Kitaoka T, Sharif M, Hanley MR, Hjelmeland LM. PMID: 8055698.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    57. Cellular adhesion regulates bFGF gene expression in human retinal pigment epithelial cells. Exp Eye Res. 1994 May; 58(5):545-52. Bost LM, Aotaki-Keen AE, Hjelmeland LM. PMID: 7925691.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    58. Fibrinolytic-assisted removal of experimental subretinal hemorrhage within seven days reduces outer retinal degeneration. Ophthalmology. 1994 Apr; 101(4):672-81. Benner JD, Hay A, Landers MB, Hjelmeland LM, Morse LS. PMID: 8152762.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    59. Increasing cell density down-regulates the expression of acidic FGF by human RPE cells in vitro. Curr Eye Res. 1993 Nov; 12(11):993-9. Kitaoka T, Bost LM, Ishigooka H, Aotaki-Keen AE, Hjelmeland LM. PMID: 7508360.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    60. A glass micropipette holder for ophthalmic surgical procedures. Am J Ophthalmol. 1993 Oct 15; 116(4):511-3. Benner JD, Magliocco M, Toth CA, Hjelmeland LM, Landers MB, Morse LS. PMID: 8213990.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Developmental expression of bFGF in the bovine retina. Invest Ophthalmol Vis Sci. 1993 Aug; 34(9):2813-23. Ishigooka H, Kitaoka T, Boutilier SB, Bost LM, Aotaki-Keen AE, Tablin F, Hjelmeland LM. PMID: 8344803.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    62. Cell density regulates differential production of bFGF transcripts. Growth Factors. 1993; 9(3):195-203. Bost LM, Hjelmeland LM. PMID: 8274297.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    63. Coexpression of FGF-5 and bFGF by the retinal pigment epithelium in vitro. Exp Eye Res. 1992 Nov; 55(5):727-34. Bost LM, Aotaki-Keen AE, Hjelmeland LM. PMID: 1478282.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    64. Comparison of photocoagulation with the argon, krypton, and diode laser indirect ophthalmoscopes in rabbit eyes. Ophthalmology. 1992 Oct; 99(10):1554-63. Benner JD, Huang M, Morse LS, Hjelmeland LM, Landers MB. PMID: 1454322.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    65. Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats. Curr Eye Res. 1992 Oct; 11(10):1005-17. Connolly SE, Hjelmeland LM, LaVail MM. PMID: 1451525.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    66. Subcellular localization of bFGF in human retinal pigment epithelium in vitro. Exp Eye Res. 1992 Aug; 55(2):203-14. Ishigooka H, Aotaki-Keen AE, Hjelmeland LM. PMID: 1426056.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    67. Stainless steel micropipette for subretinal surgery. Am J Ophthalmol. 1992 Jun 15; 113(6):716-8. Benner JD, Magliocco MT, Toth CA, Hay A, Hjelmeland LM, Landers MB, Morse LS. PMID: 1598968.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    68. An experimental model of ectropion uveae and iris neovascularization in the cat. Invest Ophthalmol Vis Sci. 1992 Apr; 33(5):1796-803. Hjelmeland LM, Stewart MW, Li J, Toth CA, Burns MS, Landers MB. PMID: 1373124.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    69. The 9E3 protein: immunolocalization in vivo and evidence for multiple forms in culture. J Cell Sci. 1992 Mar; 101 ( Pt 3):701-7. Martins-Green M, Aotaki-Keen A, Hjelmeland LM, Bissell MJ. PMID: 1325984; PMCID: PMC2937011.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    70. Ultramicrosurgical removal of subretinal hemorrhage in cats. Am J Ophthalmol. 1992 Feb 15; 113(2):175-82. Toth CA, Benner JD, Hjelmeland LM, Landers MB, Morse LS. PMID: 1550185.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    71. Detection of c-sis proto-oncogene transcripts by direct enzyme-labeled cDNA probes and in situ hybridization. In Vitro Cell Dev Biol. 1992 Feb; 28A(2):102-8. McClintock JT, Chan IJ, Thaker SR, Katial A, Taub FE, Aotaki-Keen AE, Hjelmeland LM. PMID: 1537750.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    72. Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye. Graefes Arch Clin Exp Ophthalmol. 1992; 230(1):84-90. Hjelmeland LM, Li JW, Toth CA, Landers MB. PMID: 1547974.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    73. Evaluation of a commercial recombinant tissue-type plasminogen activator preparation in the subretinal space of the cat. Arch Ophthalmol. 1991 Dec; 109(12):1731-6. Benner JD, Morse LS, Toth CA, Landers MB, Hjelmeland LM. PMID: 1841586.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    74. Altered distribution of basic fibroblast growth factor in diabetic retinopathy. Arch Ophthalmol. 1991 Jul; 109(7):1005-11. Hanneken A, de Juan E, Lutty GA, Fox GM, Schiffer S, Hjelmeland LM. PMID: 2064554.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    75. Fibrin directs early retinal damage after experimental subretinal hemorrhage. Arch Ophthalmol. 1991 May; 109(5):723-9. Toth CA, Morse LS, Hjelmeland LM, Landers MB. PMID: 2025175.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    76. Primary culture of human retinal glia. Invest Ophthalmol Vis Sci. 1991 May; 32(6):1733-8. Aotaki-Keen AE, Harvey AK, de Juan E, Hjelmeland LM. PMID: 1903364.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    77. Ultrastructural and immunocytochemical changes in retinal pigment epithelium, retinal glia, and fibroblasts in vitreous culture. Invest Ophthalmol Vis Sci. 1990 Dec; 31(12):2529-45. Vinores SA, Campochiaro PA, McGehee R, Orman W, Hackett SF, Hjelmeland LM. PMID: 1702409.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    78. Solubilization of native membrane proteins. Methods Enzymol. 1990; 182:253-64. Hjelmeland LM. PMID: 2156128.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    79. Removal of detergents from membrane proteins. Methods Enzymol. 1990; 182:277-82. Hjelmeland LM. PMID: 2314241.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    80. Retinal pigment epithelial cells produce PDGF-like proteins and secrete them into their media. Exp Eye Res. 1989 Aug; 49(2):217-27. Campochiaro PA, Sugg R, Grotendorst G, Hjelmeland LM. PMID: 2767169.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    81. Localization of basic fibroblast growth factor to the developing capillaries of the bovine retina. J Cell Physiol. 1989 Jan; 138(1):115-20. Hanneken A, Lutty GA, McLeod DS, Robey F, Harvey AK, Hjelmeland LM. PMID: 2910880.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    82. Serum is chemotactic for retinal-derived glial cells. Arch Ophthalmol. 1988 Jul; 106(7):986-90. de Juan E, Dickson JS, Hjelmeland L. PMID: 3390062.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    83. Growth factors: soluble mediators of wound repair and ocular fibrosis. Birth Defects Orig Artic Ser. 1988; 24(1):87-102. Hjelmeland LM, Harvey AK. PMID: 3052614.
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    84. Chapter 9 gliosis of the mammalian retina: Migration and proliferation of retinal glia. Progress in Retinal Research. 1988 Jan 1; 7:259-281. Hjelmeland HL, Harvey HA. .
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    85. Chemotaxis of rat retinal glia to growth factors found in repairing wounds. Invest Ophthalmol Vis Sci. 1987 Jul; 28(7):1092-9. Harvey AK, Roberge F, Hjelmeland LM. PMID: 3496317.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    86. The design and synthesis of detergents for membrane biochemistry. Methods Enzymol. 1986; 124:135-64. Hjelmeland LM. PMID: 3713521.
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    87. Chemotaxis of rat brain astrocytes to platelet derived growth factor. Brain Res. 1985 Oct 07; 344(2):249-54. Bressler JP, Grotendorst GR, Levitov C, Hjelmeland LM. PMID: 3899281.
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    88. Purification and immunochemical characterization of a low-pI form of UDP glucuronosyltransferase from mouse liver. Arch Biochem Biophys. 1984 Jun; 231(2):487-97. Mackenzie PI, Hjelmeland LM, Owens IS. PMID: 6428319.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    89. Solubilization of functional membrane proteins. Methods Enzymol. 1984; 104:305-18. Hjelmeland LM, Chrambach A. PMID: 6232441.
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    90. A new class of nonionic detergents with a gluconamide polar group. Anal Biochem. 1983 Apr 15; 130(2):485-90. Hjelmeland LM, Klee WA, Osborne JC. PMID: 6869837.
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    91. Sulfobetaine derivatives of bile acids: nondenaturing surfactants for membrane biochemistry. Anal Biochem. 1983 Apr 01; 130(1):72-82. Hjelmeland LM, Nebert DW, Osborne JC. PMID: 6869811.
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    92. Detection of binding artifacts in gel electrofocusing using a polymeric dye probe. Electrophoresis. 1983 Feb 1; 4(6):404-407. Cuono CC, Chapo CG, Chrambach CA, Hjelmeland HL. .
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    93. Formation of natural pH gradients in sequential moving boundary systems with solvent counterions II. Predicted and experimental properties. Electrophoresis. 1983 Feb 1; 4(1):27-35. Buzás BZ, Hjelmeland HL, Chrambach CA. .
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    94. Resolution and activity of adenylate cyclase components in a zwitterionic cholate derivative [3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate]. Biochemistry. 1982 Jul 20; 21(15):3650-3. Bitonti AJ, Moss J, Hjelmeland L, Vaughan M. PMID: 7115690.
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    95. Induction of microsomal dimethylnitrosamine demethylase by pyrazole. Biochem Pharmacol. 1982 Apr 01; 31(7):1245-9. Evarts RP, Haliday E, Negishi M, Hjelmeland LM. PMID: 7092919.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    96. The impact of L. G. Longsworth (1905–1981) on the theory of electrophoresis. Electrophoresis. 1982 Feb 1; 3(1):9-17. Hjelmeland HL, Chrambach CA. .
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    97. The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system. Adv Genet. 1982; 21:1-52. Nebert DW, Negishi M, Lang MA, Hjelmeland LM, Eisen HJ. PMID: 7036691.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    98. Carboxyfluorescein as a probe for liposome-cell interactions effect of impurities, and purification of the dye. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1981 Nov 1; 649(1):133-137. Ralston RE, Hjelmeland HL, Klausner KR, Weinstein WJ, Blumenthal BR. .
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    99. GTP stabilization of adenylate cyclase activated and ADP-ribosylated by choleragen. Biochem Biophys Res Commun. 1981 Sep 16; 102(1):66-74. Nakaya S, Watkins PA, Bitonti AJ, Hjelmeland LM, Moss J, Vaughan M. PMID: 7306174.
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    100. Electrophoresis in gels containing zwitterionic groups. Electrophoresis. 1981 Feb 1; 2(2):82-90. Hjelmeland HL, Allenmark AS, der Lan dB, Jackiw JB, Nguyen NN, Chrambach CA. .
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    101. Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities. Annu Rev Pharmacol Toxicol. 1981; 21:431-62. Nebert DW, Eisen HJ, Negishi M, Lang MA, Hjelmeland LM, Okey AB. PMID: 7016012.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    102. A nondenaturing zwitterionic detergent for membrane biochemistry: design and synthesis. Proc Natl Acad Sci U S A. 1980 Nov; 77(11):6368-70. Hjelmeland LM. PMID: 6935651; PMCID: PMC350285.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    103. Solubilization of active opiate receptors. Proc Natl Acad Sci U S A. 1980 Aug; 77(8):4623-7. Simonds WF, Koski G, Streaty RA, Hjelmeland LM, Klee WA. PMID: 6254034; PMCID: PMC349897.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    104. Electrofocusing of integral membrane proteins in mixtures of zwitterionic and nonionic detergents. Anal Biochem. 1979 May; 95(1):201-8. Hjelmeland LM, Nebert DW, Chrambach A. PMID: 495956.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    105. Intramolecular determination of substituent effects in hydroxylations catalyzed by cytochrome P-450. Mol Pharmacol. 1977 Jul; 13(4):634-9. Hjelmeland LM, Aronow L, Trudell JR. PMID: 887073.
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    106. Active site models of horseradish peroxidase compound I and a cytochrome P-450 analogue: electronic structure and electric field gradients. J Am Chem Soc. 1977 May 11; 99(10):3534-6. Loew GH, Kert CJ, Hjelmeland LM, Kirchner RF. PMID: 853195.
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    107. The electronic structure of chromyl chloride: a functional model for cytochrome P-450. J Am Chem Soc. 1977 May 11; 99(10):3514-5. Hjelmeland LM, Loew GH. PMID: 853192.
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    108. Models for the enzymatically active state of cytochrome p-450. International Journal of Quantum Chemistry. 1977 Jan 9; 12(S4):225-244. Loew LG, Hjelmeland HL, Kirchner KR. .
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    109. Intramolecular determination of primary kinetic isotope effects in hydroxylations catalyzed by cytochrome P-450. Biochem Biophys Res Commun. 1976 May 23; 76(2):541-9. Hjelmeland LM, Aronow L, Trudell JR. PMID: 1027445.
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    110. Molecular orbital studies of the conformation of peroxyacetic acid. Chemical Physics Letters. 1975 Apr 1; 32(2):309-314. Hjelmeland HL, Loew LG. .
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    111. Quantum chemical studies of the metabolism of the inhalation anesthetics methoxyflurane, enflurane, and isoflurane. Mol Pharmacol. 1974 May; 10(3):406-18. Loew G, Motulsky H, Trudell J, Cohen E, Hjelmeland L. PMID: 4153031.
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