HIV Envelope Protein gp120
"HIV Envelope Protein gp120" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
| Descriptor ID |
D015699
|
| MeSH Number(s) |
D12.776.964.775.325.164.249 D12.776.964.775.562.500.500 D12.776.964.970.880.325.164.249 D23.050.327.520.350
|
| Concept/Terms |
HIV Envelope Protein gp120- HIV Envelope Protein gp120
- Envelope Glycoprotein gp120, HIV
- gp120 Envelope Glycoprotein, HIV
- HIV Envelope Glycoprotein gp120
- HTLV-III gp120
- HTLV III gp120
- gp120, HTLV-III
- env Protein gp120, HIV
- gp120(HIV)
|
Below are MeSH descriptors whose meaning is more general than "HIV Envelope Protein gp120".
Below are MeSH descriptors whose meaning is more specific than "HIV Envelope Protein gp120".
This graph shows the total number of publications written about "HIV Envelope Protein gp120" by people in this website by year, and whether "HIV Envelope Protein gp120" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 9 | 4 | 13 |
| 1997 | 5 | 6 | 11 |
| 1998 | 4 | 6 | 10 |
| 1999 | 9 | 1 | 10 |
| 2000 | 5 | 3 | 8 |
| 2001 | 9 | 2 | 11 |
| 2002 | 10 | 6 | 16 |
| 2003 | 6 | 4 | 10 |
| 2004 | 8 | 6 | 14 |
| 2005 | 4 | 8 | 12 |
| 2006 | 5 | 4 | 9 |
| 2007 | 12 | 4 | 16 |
| 2008 | 2 | 3 | 5 |
| 2009 | 4 | 2 | 6 |
| 2010 | 3 | 7 | 10 |
| 2011 | 8 | 2 | 10 |
| 2012 | 4 | 5 | 9 |
| 2013 | 5 | 7 | 12 |
| 2014 | 8 | 7 | 15 |
| 2015 | 7 | 4 | 11 |
| 2016 | 8 | 4 | 12 |
| 2017 | 9 | 4 | 13 |
| 2018 | 5 | 2 | 7 |
| 2019 | 7 | 0 | 7 |
| 2020 | 4 | 2 | 6 |
| 2022 | 2 | 1 | 3 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 1 | 3 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "HIV Envelope Protein gp120" by people in Profiles.
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Involvement of endolysosome iron in HIV-1 gp120-, morphine-, and iron supplementation-induced disruption of the reactive species interactome and induction of neurotoxicity. Redox Rep. 2025 Dec; 30(1):2546496.
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A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies. Cell Rep. 2024 12 24; 43(12):115010.
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Protein Dose-Sparing Effect of AS01B Adjuvant in a Randomized Preventive HIV Vaccine Trial of ALVAC-HIV (vCP2438) and Adjuvanted Bivalent Subtype C gp120. J Infect Dis. 2024 Aug 16; 230(2):e405-e415.
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RAIN: machine learning-based identification for HIV-1 bNAbs. Nat Commun. 2024 Jun 24; 15(1):5339.
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GP120 and tenofovir alafenamide alter cannabinoid receptor 1 expression in hippocampus of mice. J Neurovirol. 2023 10; 29(5):564-576.
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CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120. Viruses. 2023 04 28; 15(5).
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HIV-1 Proteins gp120 and Tat Promote Epithelial-Mesenchymal Transition and Invasiveness of HPV-Positive and HPV-Negative Neoplastic Genital and Oral Epithelial Cells. Microbiol Spectr. 2022 12 21; 10(6):e0362222.
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HIV-1 gp120-CXCR4 recognition probed with synthetic nanomolar affinity D-peptides containing fragments of gp120 V3 loop. Eur J Med Chem. 2022 Dec 15; 244:114797.
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A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence. PLoS Pathog. 2022 05; 18(5):e1010488.
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Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 2021 01 08; 371(6525).