"Integrin alpha6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit that primarily associates with INTEGRIN BETA1 or INTEGRIN BETA4 to form laminin-binding heterodimers. Integrin alpha6 has two alternatively spliced isoforms: integrin alpha6A and integrin alpha6B, which differ in their cytoplasmic domains and are regulated in a tissue-specific and developmental stage-specific manner.
| Descriptor ID |
D039503
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.550
|
| Concept/Terms |
Integrin alpha6- Integrin alpha6
- alpha6, Integrin
- CD49f Antigens
- alpha6 Integrin
- Integrin, alpha6
- Antigens, CD49f
- CD49f Antigen
- Antigen, CD49f
- alpha(6) Integrin
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha6".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha6".
This graph shows the total number of publications written about "Integrin alpha6" by people in this website by year, and whether "Integrin alpha6" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Integrin alpha6" by people in Profiles.
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In vitro propagation of XXY human Klinefelter spermatogonial stem cells: A step towards new fertility opportunities. Front Endocrinol (Lausanne). 2022; 13:1002279.
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Progenitor identification and SARS-CoV-2 infection in human distal lung organoids. Nature. 2020 12; 588(7839):670-675.
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Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020 07 09; 136(2):210-223.
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CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes. Neuron. 2020 08 05; 107(3):436-453.e12.
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The lymph node stromal laminin α5 shapes alloimmunity. J Clin Invest. 2020 05 01; 130(5):2602-2619.
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Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018 07 03; 8(1):10019.
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Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population. Stem Cell Reports. 2017 05 09; 8(5):1392-1407.
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Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis. Nat Commun. 2016 08 18; 7:12564.
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CD66 and CD49f expressing cells are associated with distinct neoplastic phenotypes and progression in human cervical cancer. Eur J Cancer. 2016 06; 60:166-78.
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Differential gene expression profiling of functionally and developmentally distinct human prostate epithelial populations. Prostate. 2015 May; 75(7):764-76.