Craig H Warden

Title(s)Professor Emeritus, Pediatrics
SchoolSchool of Medicine
Address1122A The Grove
CA 95616
Phone530-752-4187
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    Collapse Research 
    Collapse Research Activities and Funding
    Positional cloning of obesity genes from congenic mice
    NIH/NIDDK R01DK069978Apr 15, 2006 - Mar 31, 2011
    Role: Principal Investigator
    GENES CAUSING SPONTANEOUS OBESITY
    NIH/NIDDK R01DK053993Jun 1, 1998 - May 31, 2003
    Role: Principal Investigator
    Rapid isolation of diet-responsive obesity genes
    NIH/NIDDK R01DK052581Sep 1, 1996 - Feb 28, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. In vivo emergence of beige-like fat in chickens as physiological adaptation to cold environments. Amino Acids. 2021 Mar; 53(3):381-393. Sotome R, Hirasawa A, Kikusato M, Amo T, Furukawa K, Kuriyagawa A, Watanabe K, Collin A, Shirakawa H, Hirakawa R, Tanitaka Y, Takahashi H, Wu G, Nochi T, Shimmura T, Warden CH, Toyomizu M. PMID: 33598768; PMCID: PMC7979618.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    2. Corrigendum: How Can We Define "Optimal Microbiota?": A Comparative Review of Structure and Functions of Microbiota of Animals, Fish, and Plants in Agriculture. Front Nutr. 2018; 5:113. Ikeda-Ohtsubo W, Brugman S, Warden CH, Rebel JMJ, Folkerts G, Pieterse CMJ. PMID: 30542651; PMCID: PMC6279912.
      View in: PubMed   Mentions: 1  
    3. How Can We Define "Optimal Microbiota?": A Comparative Review of Structure and Functions of Microbiota of Animals, Fish, and Plants in Agriculture. Front Nutr. 2018; 5:90. Ikeda-Ohtsubo W, Brugman S, Warden CH, Rebel JMJ, Folkerts G, Pieterse CMJ. PMID: 30333981; PMCID: PMC6176000.
      View in: PubMed   Mentions: 23  
    4. Chow fed UC Davis strain female Lepr fatty Zucker rats exhibit mild glucose intolerance, hypertriglyceridemia, and increased urine volume, all reduced by a Brown Norway strain chromosome 1 congenic donor region. PLoS One. 2017; 12(12):e0188175. Warden CH, Bettaieb A, Min E, Fisler JS, Haj FG, Stern JS. PMID: 29211750; PMCID: PMC5718614.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Design and implementation of the Resuscitation Outcomes Consortium Pragmatic Airway Resuscitation Trial (PART). Resuscitation. 2016 Apr; 101:57-64. Wang HE, Prince DK, Stephens SW, Herren H, Daya M, Richmond N, Carlson J, Warden C, Colella MR, Brienza A, Aufderheide TP, Idris AH, Schmicker R, May S, Nichol G. PMID: 26851059; PMCID: PMC4792760.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    6. Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2. BMC Genomics. 2015 Jan 23; 16:16. Gularte-M?rida R, Farber CR, Verdugo RA, Islas-Trejo A, Famula TR, Warden CH, Medrano JF. PMID: 25613955; PMCID: PMC4308015.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    7. Brown Norway chromosome 1 congenic reduces symptoms of renal disease in fatty Zucker rats. PLoS One. 2014; 9(1):e87770. Warden CH, Slupsky C, Griffey SM, Bettaieb A, Min E, Le A, Fisler JS, Hansen S, Haj F, Stern JS. PMID: 24498189; PMCID: PMC3909223.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Chapter 23 Genetics of Human Obesity. . 2013 Jan 1; 427-444. Fisler FJ, Warden WC. .
      View in: Publisher Site   Mentions:
    9. Leptin receptor interacts with rat chromosome 1 to regulate renal disease traits. Physiol Genomics. 2012 Nov 01; 44(21):1052-62. Warden CH, Gularte-M?rida R, Fisler JS, Hansen S, Shibata N, Le A, Medrano JF, Stern JS. PMID: 22968639; PMCID: PMC3615576.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Four out of eight genes in a mouse chromosome 7 congenic donor region are candidate obesity genes. Physiol Genomics. 2011 Sep 22; 43(18):1049-55. Sarahan KA, Fisler JS, Warden CH. PMID: 21730028; PMCID: PMC3180740.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Serious limitations of the QTL/microarray approach for QTL gene discovery. BMC Biol. 2010 Jul 12; 8:96. Verdugo RA, Farber CR, Warden CH, Medrano JF. PMID: 20624276; PMCID: PMC2919467.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    12. Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines. J Cereb Blood Flow Metab. 2010 Nov; 30(11):1825-33. Haines BA, Mehta SL, Pratt SM, Warden CH, Li PA. PMID: 20407461; PMCID: PMC2948647.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    13. Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats. Physiol Genomics. 2010 May; 41(3):297-305. Kim K, Warden CH, Griffey SM, Vilches-Moure JG, Hansen S, Cuppen E, Nijman IJ, Chiu S, Stern JS. PMID: 20159938; PMCID: PMC2869106.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    14. Histological, immunocytochemical, and morphometrical analyses of pancreatic islets in the BSB mouse model of obesity. Anat Rec (Hoboken). 2010 Jan; 293(1):108-16. Slavin BG, Zarow C, Warden CH, Fisler JS. PMID: 19798700.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    15. Obesity: from animal models to human genetics to practical applications. Prog Mol Biol Transl Sci. 2010; 94:373-89. Warden CH, Fisler JS. PMID: 21036332.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    16. Mouse hepatic lipase alleles with variable effects on lipoprotein composition and size. J Lipid Res. 2010 May; 51(5):1035-48. Pratt SM, Chiu S, Espinal GM, Shibata NM, Wong H, Warden CH. PMID: 19965617; PMCID: PMC2853430.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    17. Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents. J Clin Invest. 2009 Aug; 119(8):2291-303. Wallingford N, Perroud B, Gao Q, Coppola A, Gyengesi E, Liu ZW, Gao XB, Diament A, Haus KA, Shariat-Madar Z, Mahdi F, Wardlaw SL, Schmaier AH, Warden CH, Diano S. PMID: 19620781; PMCID: PMC2719925.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    18. Maternal influence of prolyl endopeptidase on fat mass of adult progeny. Int J Obes (Lond). 2009 Sep; 33(9):1013-22. Warden CH, Fisler JS, Espinal G, Graham J, Havel PJ, Perroud B. PMID: 19564876; PMCID: PMC2743752.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    19. In vivo multiplex quantitative analysis of 3 forms of alpha melanocyte stimulating hormone in pituitary of prolyl endopeptidase deficient mice. Mol Brain. 2009 Jun 02; 2:14. Perroud B, Alvarado RJ, Espinal GM, Morado AR, Phinney BS, Warden CH. PMID: 19490636; PMCID: PMC2698928.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    20. Evidence of maternal QTL affecting growth and obesity in adult mice. Mamm Genome. 2009 May; 20(5):269-80. Casellas J, Farber CR, Gularte RJ, Haus KA, Warden CH, Medrano JF. PMID: 19399551; PMCID: PMC2690847.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    21. Gene-nutrient and gene-physical activity summary--genetics viewpoint. Obesity (Silver Spring). 2008 Dec; 16 Suppl 3:S55-9. Warden CH, Fisler JS. PMID: 19037215.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    22. Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice. Exp Gerontol. 2008 Dec; 43(12):1069-76. Asami DK, McDonald RB, Hagopian K, Horwitz BA, Warman D, Hsiao A, Warden C, Ramsey JJ. PMID: 18852040; PMCID: PMC2614627.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    23. Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice. Exp Gerontol. 2008 Dec; 43(12):1061-8. McDonald RB, Walker KM, Warman DB, Griffey SM, Warden CH, Ramsey JJ, Horwitz BA. PMID: 18854208.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    24. Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass. Int J Obes (Lond). 2008 Sep; 32(9):1395-406. Kim K, Perroud B, Espinal G, Kachinskas D, Austrheim-Smith I, Wolfe BM, Warden CH. PMID: 18645576.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    25. Overexpression of UCP2 Protects Thalamic Neurons following Global Ischemia in the Mouse. Journal of Cerebral Blood Flow & Metabolism. 2008 Jun 1; 28(6):1273-1273. Deierborg DT, Wieloch WT, Diano DS, Warden WC, Horvath HT, Mattiasson MG. .
      View in: Publisher Site   Mentions:
    26. Comparisons of diets used in animal models of high-fat feeding. Cell Metab. 2008 Apr; 7(4):277. Warden CH, Fisler JS. PMID: 18396128; PMCID: PMC2394560.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    27. Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse. J Cereb Blood Flow Metab. 2008 Jun; 28(6):1186-95. Deierborg T, Deierborg Olsson T, Wieloch T, Diano S, Warden CH, Horvath TL, Mattiasson G. PMID: 18301432; PMCID: PMC2642535.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    28. Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study. Am J Clin Nutr. 2007 Aug; 86(2):514-21. Halsted CH, Wong DH, Peerson JM, Warden CH, Refsum H, Smith AD, Nygård OK, Ueland PM, Vollset SE, Tell GS. PMID: 17684227.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    29. Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons. Mol Cell Endocrinol. 2007 Sep 30; 276(1-2):24-35. Oort PJ, Warden CH, Baumann TK, Knotts TA, Adams SH. PMID: 17689857.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    30. Sequential changes in superoxide production, anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens. FEBS Lett. 2007 Jul 24; 581(18):3461-7. Mujahid A, Akiba Y, Warden CH, Toyomizu M. PMID: 17612532.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    31. Identification of positional candidate genes for body weight and adiposity in subcongenic mice. Physiol Genomics. 2007 Sep 19; 31(1):75-85. Chiu S, Kim K, Haus KA, Espinal GM, Millon LV, Warden CH. PMID: 17536020.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    32. The current and future search for obesity genes. Am J Clin Nutr. 2007 Jan; 85(1):1-2. Fisler JS, Warden CH. PMID: 17209169.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Chapter 19 Genetic Analysis of Rodent Obesity and Diabetes. . 2007 Jan 1; III(Nat Rev Genet42003):617-636. Chiu CS, Fisler FJ, Warden WC. .
      View in: Publisher Site   Mentions:
    34. Uncoupling proteins, dietary fat and the metabolic syndrome. Nutr Metab (Lond). 2006 Sep 12; 3:38. Fisler JS, Warden CH. PMID: 16968550; PMCID: PMC1592539.
      View in: PubMed   Mentions: 42  
    35. Genetics of obesity in Hispanic children. Am J Clin Nutr. 2006 Sep; 84(3):473-4. Fisler JS, Warden CH. PMID: 16960158.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Gene–Gene Epistasis and Gene–Environment Interactions Influence Diabetes and Obesity. . 2006 Mar 24; 135-151. Chiu CS, Diament DA, Fisler FJ, Warden WC. .
      View in: Publisher Site   Mentions:
    37. The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr. 2005 Nov; 94(5):623-32. Kaput J, Ordovas JM, Ferguson L, van Ommen B, Rodriguez RL, Allen L, Ames BN, Dawson K, German B, Krauss R, Malyj W, Archer MC, Barnes S, Bartholomew A, Birk R, van Bladeren P, Bradford KJ, Brown KH, Caetano R, Castle D, Chadwick R, Clarke S, Clément K, Cooney CA, Corella D, Manica da Cruz IB, Daniel H, Duster T, Ebbesson SO, Elliott R, Fairweather-Tait S, Felton J, Fenech M, Finley JW, Fogg-Johnson N, Gill-Garrison R, Gibney MJ, Gillies PJ, Gustafsson JA, Hartman JL, He L, Hwang JK, Jais JP, Jang Y, Joost H, Junien C, Kanter M, Kibbe WA, Koletzko B, Korf BR, Kornman K, Krempin DW, Langin D, Lauren DR, Ho Lee J, Leveille GA, Lin SJ, Mathers J, Mayne M, McNabb W, Milner JA, Morgan P, Muller M, Nikolsky Y, van der Ouderaa F, Park T, Pensel N, Perez-Jimenez F, Poutanen K, Roberts M, Saris WH, Schuster G, Shelling AN, Simopoulos AP, Southon S, Tai ES, Towne B, Trayhurn P, Uauy R, Visek WJ, Warden C, Weiss R, Wiencke J, Winkler J, Wolff GL, Zhao-Wilson X, Zucker JD. PMID: 16277761.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    38. Dietary fat and genotype: toward individualized prescriptions for lifestyle changes. Am J Clin Nutr. 2005 Jun; 81(6):1255-6. Fisler JS, Warden CH. PMID: 15941873.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet. 2004 Nov; 36(11):1133-7. Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium. PMID: 15514660.
      View in: PubMed   Mentions: 562     Fields:    Translation:HumansAnimals
    40. Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice. J Lipid Res. 2004 Nov; 45(11):2063-70. Yi N, Chiu S, Allison DB, Fisler JS, Warden CH. PMID: 15314098.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    41. The yellow agouti mutation alters some but not all responses to diet and exercise. Obes Res. 2004 Aug; 12(8):1243-55. Chiu S, Fisler JS, Espinal GM, Havel PJ, Stern JS, Warden CH. PMID: 15340107.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    42. A novel mouse Chromosome 2 congenic strain with obesity phenotypes. Mamm Genome. 2004 Jun; 15(6):452-9. Diament AL, Farahani P, Chiu S, Fisler J, Warden CH. PMID: 15181537.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    43. Identification of a congenic mouse line with obesity and body length phenotypes. Mamm Genome. 2004 Jun; 15(6):460-71. Warden CH, Stone S, Chiu S, Diament AL, Corva P, Shattuck D, Riley R, Hunt SC, Easlick J, Fisler JS, Medrano JF. PMID: 15181538.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    44. Characterization of epistasis influencing complex spontaneous obesity in the BSB model. Genetics. 2004 May; 167(1):399-409. Yi N, Diament A, Chiu S, Kim K, Allison DB, Fisler JS, Warden CH. PMID: 15166164; PMCID: PMC1470871.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    45. Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin. Obes Res. 2004 Feb; 12(2):191-204. Farahani P, Chiu S, Bowlus CL, Boffelli D, Lee E, Fisler JS, Krauss RM, Warden CH. PMID: 14981211.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    46. Reciprocal hemizygosity analysis of mouse hepatic lipase reveals influence on obesity. Obes Res. 2004 Feb; 12(2):292-305. Farahani P, Fisler JS, Wong H, Diament AL, Yi N, Warden CH. PMID: 14981222.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    47. Multiple linked mouse chromosome 7 loci influence body fat mass. Int J Obes Relat Metab Disord. 2004 Feb; 28(2):199-210. Diament AL, Warden CH. PMID: 14569280.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    48. Epistasis among genes is a universal phenomenon in obesity: evidence from rodent models. Nutrition. 2004 Jan; 20(1):74-7. Warden CH, Yi N, Fisler J. PMID: 14698018.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    49. Studies of natural allele effects in mice can be used to identify genes causing common human obesity. Obes Rev. 2003 Nov; 4(4):249-55. Diament AL, Fisler JS, Warden CH. PMID: 14649375.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    50. Effects of inhibiting transcription and protein synthesis on basal and insulin-stimulated leptin gene expression and leptin secretion in cultured rat adipocytes. Biochem Biophys Res Commun. 2003 Aug 08; 307(4):907-14. Moreno-Aliaga MJ, Stanhope KL, Gregoire FM, Warden CH, Havel PJ. PMID: 12878197.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    51. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med. 2003 Aug; 9(8):1062-8. Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K, Wieloch T. PMID: 12858170.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCells
    52. Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice. Int J Obes Relat Metab Disord. 2003 Apr; 27(4):433-42. Horvath TL, Diano S, Miyamoto S, Barry S, Gatti S, Alberati D, Livak F, Lombardi A, Moreno M, Goglia F, Mor G, Hamilton J, Kachinskas D, Horwitz B, Warden CH. PMID: 12664076.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    53. Racial differences in susceptibility to obesity. Am J Clin Nutr. 2003 03; 77(3):751; author reply 751-2; discussion 752-3. Cooper R, Luke A. PMID: 12600873.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Uncoupling protein 2 in primary pain and temperature afferents of the spinal cord. Brain Res. 2002 Nov 15; 955(1-2):260-3. Horvath B, Spies C, Warden CH, Diano S, Horvath TL. PMID: 12419545.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    55. Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol. 2002 Aug 01; 64(3):363-7. Bechmann I, Diano S, Warden CH, Bartfai T, Nitsch R, Horvath TL. PMID: 12147286.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    56. Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. Biochem Pharmacol. 2002 Aug 01; 64(3):369-74. Horvath B, Spies C, Horvath G, Kox WJ, Miyamoto S, Barry S, Warden CH, Bechmann I, Diano S, Heemskerk J, Horvath TL. PMID: 12147287.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    57. Uncoupling proteins: a molecular basis for racial differences in energy expenditure (and obesity?). Am J Clin Nutr. 2002 Apr; 75(4):607-8. Schonfeld-Warden NA, Warden CH. PMID: 11916746.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    58. Physiological effects of variants in human uncoupling proteins: UCP2 influences body-mass index. Biochem Soc Trans. 2001 Nov; 29(Pt 6):777-84. Schonfeld-Warden NA, Warden CH. PMID: 11709074.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    59. Biological influences on obesity. Pediatr Clin North Am. 2001 Aug; 48(4):879-91. Warden NA, Warden CH. PMID: 11494641.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    60. Structure-function relationships in UCP1, UCP2 and chimeras: EPR analysis and retinoic acid activation of UCP2. Eur J Biochem. 2001 Feb; 268(4):903-13. Chomiki N, Voss JC, Warden CH. PMID: 11179956.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    61. Mitochondrial uncoupling protein 2 (UCP2) in the nonhuman primate brain and pituitary. Endocrinology. 2000 Nov; 141(11):4226-38. Diano S, Urbanski HF, Horvath B, Bechmann I, Kagiya A, Nemeth G, Naftolin F, Warden CH, Horvath TL. PMID: 11089557.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    62. Effects of 2-G exposure on temperature regulation, circadian rhythms, and adiposity in UCP2/3 transgenic mice. J Appl Physiol (1985). 2000 Oct; 89(4):1491-8. Fuller PM, Warden CH, Barry SJ, Fuller CA. PMID: 11007587.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    63. Associations between uncoupling protein 2, body composition, and resting energy expenditure in lean and obese African American, white, and Asian children. Am J Clin Nutr. 2000 Jun; 71(6):1405-20. Yanovski JA, Diament AL, Sovik KN, Nguyen TT, Li H, Sebring NG, Warden CH. PMID: 10837279; PMCID: PMC4495659.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    64. Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers. J Neurosci. 1999 Dec 01; 19(23):10417-27. Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S. PMID: 10575039; PMCID: PMC6782406.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    65. T(3) stimulates resting metabolism and UCP-2 and UCP-3 mRNA but not nonphosphorylating mitochondrial respiration in mice. Am J Physiol. 1999 08; 277(2):E380-9. Jekabsons MB, Gregoire FM, Schonfeld-Warden NA, Warden CH, Horwitz BA. PMID: 10444435.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    66. Obesity and increased contractile activity influence the protein content of UCP2 in human skeletal muscle. Int J Obes Relat Metab Disord. 1999 Jun; 23 Suppl 6:S68-71. Simoneau JA, Kelley DE, Warden C. PMID: 10454129.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes. Diabetologia. 1999 Jun; 42(6):688-92. Cassell PG, Neverova M, Janmohamed S, Uwakwe N, Qureshi A, McCarthy MI, Saker PJ, Albon L, Kopelman P, Noonan K, Easlick J, Ramachandran A, Snehalatha C, Pecqueur C, Ricquier D, Warden C, Hitman GA. PMID: 10382588.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    68. Genetics of uncoupling proteins in humans. Int J Obes Relat Metab Disord. 1999 Jun; 23 Suppl 6:S46-8. Warden C. PMID: 10454122.
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    69. Gene-environment interaction: a significant diet-dependent obesity locus demonstrated in a congenic segment on mouse chromosome 7. Mamm Genome. 1999 May; 10(5):457-62. York B, Truett AA, Monteiro MP, Barry SJ, Warden CH, Naggert JK, Maddatu TP, West DB. PMID: 10337618.
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    70. BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast. J Biol Chem. 1998 Dec 18; 273(51):34611-5. Sanchis D, Fleury C, Chomiki N, Goubern M, Huang Q, Neverova M, Grégoire F, Easlick J, Raimbault S, Lévi-Meyrueis C, Miroux B, Collins S, Seldin M, Richard D, Warden C, Bouillaud F, Ricquier D. PMID: 9852133.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    71. Overexpression of muscle uncoupling protein 2 content in human obesity associates with reduced skeletal muscle lipid utilization. FASEB J. 1998 Dec; 12(15):1739-45. Simoneau JA, Kelley DE, Neverova M, Warden CH. PMID: 9837864.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    72. Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. Hum Mol Genet. 1998 Sep; 7(9):1431-5. Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP, Easlick J, Warden CH, Pecqueur C, Raimbault S, Ricquier D, Silver MH, Shuldiner AR, Solanes G, Lowell BB, Chung WK, Leibel RL, Pratley R, Ravussin E. PMID: 9700198.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    73. Cloning and developmental regulation of a novel member of the insulin-like gene family in Caenorhabditis elegans. Biochem Biophys Res Commun. 1998 Aug 19; 249(2):385-90. Gregoire FM, Chomiki N, Kachinskas D, Warden CH. PMID: 9712706.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    74. Mutation screening of the human UCP 2 gene in normoglycemic and NIDDM morbidly obese patients: lack of association between new UCP 2 polymorphisms and obesity in French Caucasians. Diabetes. 1998 May; 47(5):840-2. Otabe S, Clement K, Rich N, Warden C, Pecqueur C, Neverova M, Raimbault S, Guy-Grand B, Basdevant A, Ricquier D, Froguel P, Vasseur F. PMID: 9588459.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    75. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology. 1998 Feb; 139(2):551-8. Mueller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizuno TM, Warden CH, Stern JS, Havel PJ. PMID: 9449624.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    76. Integrated methods to solve the biological basis of common diseases. Methods. 1997 Dec; 13(4):347-57. Warden CH, Fisler JS. PMID: 9480781.
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    77. Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum Mol Genet. 1997 Oct; 6(11):1887-9. Bouchard C, Pérusse L, Chagnon YC, Warden C, Ricquier D. PMID: 9302267.
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    78. Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. J Clin Invest. 1997 Sep 01; 100(5):1240-7. Lembertas AV, Pérusse L, Chagnon YC, Fisler JS, Warden CH, Purcell-Huynh DA, Dionne FT, Gagnon J, Nadeau A, Lusis AJ, Bouchard C. PMID: 9276742; PMCID: PMC508301.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    79. Mapping of mouse obesity genes: A generic approach to a complex trait. J Nutr. 1997 Sep; 127(9):1909S-1916S. Fisler JS, Warden CH. PMID: 9278581.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    80. Pediatric obesity. An overview of etiology and treatment. Pediatr Clin North Am. 1997 Apr; 44(2):339-61. Schonfeld-Warden N, Warden CH. PMID: 9130924.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    81. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet. 1997 Mar; 15(3):269-72. Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier D, Warden CH. PMID: 9054939.
      View in: PubMed   Mentions: 304     Fields:    Translation:HumansAnimalsCells
    82. Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse chromosome 9. Mamm Genome. 1996 Jul; 7(7):554-5. Xia Y, Welch CL, Warden CH, Lange E, Fukao T, Lusis AJ, Gatti RA. PMID: 8672141.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    83. Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul; 37(7):1406-21. Welch CL, Xia YR, Shechter I, Farese R, Mehrabian M, Mehdizadeh S, Warden CH, Lusis AJ. PMID: 8827514.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    84. The glutathione peroxidase gene, Gpx1, maps to mouse chromosome 9. Mamm Genome. 1996 Jun; 7(6):465-6. Mehdizadeh S, Warden CH, Wen PZ, Xia YR, Mehrabian M, Lusis AJ. PMID: 8662233.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    85. Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. J Clin Invest. 1996 May 01; 97(9):2111-8. Wu DA, Bu X, Warden CH, Shen DD, Jeng CY, Sheu WH, Fuh MM, Katsuya T, Dzau VJ, Reaven GM, Lusis AJ, Rotter JI, Chen YD. PMID: 8621801; PMCID: PMC507286.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    86. Multilocus genetic determinants of LDL particle size in coronary artery disease families. Am J Hum Genet. 1996 Mar; 58(3):585-94. Rotter JI, Bu X, Cantor RM, Warden CH, Brown J, Gray RJ, Blanche PJ, Krauss RM, Lusis AJ. PMID: 8644718; PMCID: PMC1914567.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    87. A locus on the X chromosome is linked to body length in mice. Mamm Genome. 1996 Mar; 7(3):171-3. Lembertas AV, Fisher JS, Warden CH, Wen PZ, Xia YR, Lusis AJ. PMID: 8833234.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    88. Identification of four chromosomal loci determining obesity in a multifactorial mouse model. J Clin Invest. 1995 Apr; 95(4):1545-52. Warden CH, Fisler JS, Shoemaker SM, Wen PZ, Svenson KL, Pace MJ, Lusis AJ. PMID: 7706460; PMCID: PMC295638.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    89. Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice. Biochem Genet. 1994 Dec; 32(11-12):397-407. Hyman RW, Frank S, Warden CH, Daluiski A, Heller R, Lusis AJ. PMID: 7748156.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    90. Mouse cellular nucleic acid binding proteins: a highly conserved family identified by genetic mapping and sequencing. Genomics. 1994 Nov 01; 24(1):14-9. Warden CH, Krisans SK, Purcell-Huynh D, Leete LM, Daluiski A, Diep A, Taylor BA, Lusis AJ. PMID: 7896269.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    91. Localization of murine macrophage inducible nitric oxide synthase to mouse chromosome 11. Genomics. 1994 Aug; 22(3):646-7. Mehrabian M, Xia YR, Wen PZ, Warden CH, Herschman HR, Lusis AJ. PMID: 7528168.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    92. Liver fatty acid composition correlates with body fat and sex in a multigenic mouse model of obesity. Am J Clin Nutr. 1994 Jul; 60(1):61-7. Phinney SD, Fisler JS, Tang AB, Warden CH. PMID: 8017339.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    93. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci. Hum Genet. 1994 Jun; 93(6):639-48. Bu X, Warden CH, Xia YR, De Meester C, Puppione DL, Teruya S, Lokensgard B, Daneshmand S, Brown J, Gray RJ, et al. PMID: 8005588.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    94. Evidence for linkage of the apolipoprotein A-II locus to plasma apolipoprotein A-II and free fatty acid levels in mice and humans. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10886-90. Warden CH, Daluiski A, Bu X, Purcell-Huynh DA, De Meester C, Shieh BH, Puppione DL, Gray RM, Reaven GM, Chen YD, et al. PMID: 8248186; PMCID: PMC47883.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    95. Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov; 18(2):295-307. Warden CH, Mehrabian M, He KY, Yoon MY, Diep A, Xia YR, Wen PZ, Svenson KL, Sparkes RS, Lusis AJ. PMID: 8288233.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    96. Chromosomal organization of mammalian POU domain factors. Genomics. 1993 Oct; 18(1):126-30. Xia YR, Andersen B, Mehrabian M, Diep AT, Warden CH, Mohandas T, McEvilly RJ, Rosenfeld MG, Lusis AJ. PMID: 8276396.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    97. Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice. J Biol Chem. 1993 Sep 25; 268(27):20676-82. Hedrick CC, Castellani LW, Warden CH, Puppione DL, Lusis AJ. PMID: 8376417.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    98. Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2. Genomics. 1993 Sep; 17(3):780-1. Xia YR, Bachinsky DR, Smith JA, McCluskey RT, Warden CH, Lusis AJ. PMID: 8244399.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    99. Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model. J Clin Invest. 1993 Aug; 92(2):773-9. Warden CH, Fisler JS, Pace MJ, Svenson KL, Lusis AJ. PMID: 8349816; PMCID: PMC294913.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    100. Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase. J Lipid Res. 1993 Aug; 34(8):1451-5. Warden CH, Davis RC, Yoon MY, Hui DY, Svenson K, Xia YR, Diep A, He KY, Lusis AJ. PMID: 8105016.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    101. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II. Science. 1993 Jul 23; 261(5120):469-72. Warden CH, Hedrick CC, Qiao JH, Castellani LW, Lusis AJ. PMID: 8332912.
      View in: PubMed   Mentions: 80     Fields:    Translation:Animals
    102. BSB: a new mouse model of multigenic obesity. Obes Res. 1993 Jul; 1(4):271-80. Fisler JS, Warden CH, Pace MJ, Lusis AJ. PMID: 16353357.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    103. Chromosomal organization of the inducible and constitutive prostaglandin synthase/cyclooxygenase genes in mouse. Genomics. 1993 Feb; 15(2):458-60. Wen PZ, Warden C, Fletcher BS, Kujubu DA, Herschman HR, Lusis AJ. PMID: 8449520.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    104. Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res. 1992 May; 33(5):711-25. Hwa JJ, Zollman S, Warden CH, Taylor BA, Edwards PA, Fogelman AM, Lusis AJ. PMID: 1352323.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    105. Localization of the gene for apolipoprotein D on mouse chromosome 16. Genomics. 1992 Apr; 12(4):851-2. Warden CH, Diep A, Taylor BA, Lusis AJ. PMID: 1572665.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    106. A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition. J Biol Chem. 1990 Sep 25; 265(27):16380-8. Doolittle MH, LeBoeuf RC, Warden CH, Bee LM, Lusis AJ. PMID: 2118905.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    107. Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin: cholesterol acyltransferase gene. Evidence for expression in brain and testes as well as liver. J Biol Chem. 1989 Dec 25; 264(36):21573-81. Warden CH, Langner CA, Gordon JI, Taylor BA, McLean JW, Lusis AJ. PMID: 2600083.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    108. Macrophage lipoprotein receptors. J Cell Sci Suppl. 1988; 9:135-49. Fogelman AM, Van Lenten BJ, Warden C, Haberland ME, Edwards PA. PMID: 2855802.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    109. Regulation of choline kinase activity and phosphatidylcholine biosynthesis by mitogenic growth factors in 3T3 fibroblasts. J Biol Chem. 1985 May 25; 260(10):6006-11. Warden CH, Friedkin M. PMID: 2987212.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    110. Regulation of phosphatidylcholine biosynthesis by mitogenic growth factors. Biochim Biophys Acta. 1984 Mar 07; 792(3):270-80. Warden CH, Friedkin M. PMID: 6365172.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    111. Acid-soluble precursors and derivatives of phospholipids increase after stimulation of quiescent Swiss 3T3 mouse fibroblasts with serum. Biochem Biophys Res Commun. 1980 May 30; 94(2):690-6. Warden CH, Friedkin M, Geiger PJ. PMID: 7396928.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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