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Fawaz Haj, PhD

Title(s)Professor, Nutrition
SchoolUniversity of California, Davis
Phone530-752-3214
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of T cell protein-tyrosine phosphatase in pancreatic islet function
    NIH/NIDDK R01DK095359Jul 1, 2014 - Jun 30, 2018
    Role: Principal Investigator
    Role of adipose protein-tyrosine phosphatase 1B in glucose homeostasis and body m
    NIH/NIDDK R01DK090492Sep 20, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Role of Protein-Tyrosine Phosphatase 1B in Pancreatic Islet Function
    NIH/NIDDK R56DK084317Jul 1, 2010 - Jun 30, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bailey KA, Moreno E, Haj FG, Simon SI, Passerini AG. Mechanoregulation of p38 activity enhances endoplasmic reticulum stress-mediated inflammation by arterial endothelium. FASEB J. 2019 Nov; 33(11):12888-12899. PMID: 31499005.
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    2. Yang HS, Haj FG, Lee M, Kang I, Zhang G, Lee Y. Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells. Nutrients. 2019 May 01; 11(5). PMID: 31052468.
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    3. Li Q, Kailemia MJ, Merleev AA, Xu G, Serie D, Danan LM, Haj FG, Maverakis E, Lebrilla CB. Site-Specific Glycosylation Quantitation of 50 Serum Glycoproteins Enhanced by Predictive Glycopeptidomics for Improved Disease Biomarker Discovery. Anal Chem. 2019 04 16; 91(8):5433-5445. PMID: 30882205.
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    4. Napimoga MH, Rocha EP, Trindade-da-Silva CA, Demasi APD, Martinez EF, Macedo CG, Abdalla HB, Bettaieb A, Haj FG, Clemente-Napimoga JT, Inceoglu B, Hammock BD. Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res. 2018 Oct; 53(5):743-749. PMID: 29851077.
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    5. Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metab. 2018 May 01; 27(5):1156. PMID: 29719228.
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    6. Pérez S, Finamor I, Martí-Andrés P, Pereda J, Campos A, Domingues R, Haj F, Sabater L, de-Madaria E, Sastre J. Role of obesity in the release of extracellular nucleosomes in acute pancreatitis: a clinical and experimental study. Int J Obes (Lond). 2019 01; 43(1):158-168. PMID: 29717278.
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    7. Warden CH, Bettaieb A, Min E, Fisler JS, Haj FG, Stern JS. Chow fed UC Davis strain female Lepr fatty Zucker rats exhibit mild glucose intolerance, hypertriglyceridemia, and increased urine volume, all reduced by a Brown Norway strain chromosome 1 congenic donor region. PLoS One. 2017; 12(12):e0188175. PMID: 29211750.
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    8. Cremonini E, Wang Z, Bettaieb A, Adamo AM, Daveri E, Mills DA, Kalanetra KM, Haj FG, Karakas S, Oteiza PI. (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. Redox Biol. 2018 04; 14:588-599. PMID: 29154190.
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    9. Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metab. 2017 Sep 05; 26(3):539-546.e5. PMID: 28877457.
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    10. Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:68-78. PMID: 28847566.
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    11. Bailey KA, Haj FG, Simon SI, Passerini AG. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. Sci Rep. 2017 08 15; 7(1):8196. PMID: 28811527.
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    12. Ito Y, Hsu MF, Bettaieb A, Koike S, Mello A, Calvo-Rubio M, Villalba JM, Haj FG. Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury. Metabolism. 2017 11; 76:56-69. PMID: 28987240.
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    13. Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2758-2765. PMID: 28757338.
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    14. Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG. Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury. FEBS J. 2017 07; 284(13):1970-1986. PMID: 28485854.
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    15. Trindade-da-Silva CA, Bettaieb A, Napimoga MH, Lee KSS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD. Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis. J Pharmacol Exp Ther. 2017 06; 361(3):408-416. PMID: 28356494.
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    16. Hsu MF, Bettaieb A, Ito Y, Graham J, Havel PJ, Haj FG. Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria. Sci Rep. 2017 03 28; 7(1):461. PMID: 28352079.
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    17. Bettaieb A, Cremonini E, Kang H, Kang J, Haj FG, Oteiza PI. Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. Int J Biochem Cell Biol. 2016 12; 81(Pt B):383-392. PMID: 27592457.
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    18. Hsu MF, Pan KT, Chang FY, Khoo KH, Urlaub H, Cheng CF, Chang GD, Haj FG, Meng TC. S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling. Free Radic Biol Med. 2016 10; 99:199-213. PMID: 27521458.
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    19. Bettaieb A, Koike S, Chahed S, Bachaalany S, Griffey S, Sastre J, Haj FG. Pancreatic Protein Tyrosine Phosphatase 1B Deficiency Exacerbates Acute Pancreatitis in Mice. Am J Pathol. 2016 08; 186(8):2043-2054. PMID: 27461362.
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    20. Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). PMID: 27162031.
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    21. Ahmed Bettaieb, Ellen Hosein, Samah Chahed, Ahlam Abdulaziz, Heidi R. Kucera, Nilesh W. Gaikwad, Fawaz G. Haj. Erratum: Decreased adiposity and enhanced glucose tolerance in shikonin treated mice. Obesity. 2016 May 1; 24(5):1192-1193.
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    22. Tomilov A, Tomilova N, Shan Y, Hagopian K, Bettaieb A, Kim K, Pelicci PG, Haj F, Ramsey J, Cortopassi G. p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria. J Biol Chem. 2016 Jun 10; 291(24):12575-85. PMID: 27059956.
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    23. Cremonini E, Bettaieb A, Haj FG, Fraga CG, Oteiza PI. (-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice. Arch Biochem Biophys. 2016 06 01; 599:13-21. PMID: 26968772.
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    24. McGavigan AK, Garibay D, Henseler ZM, Chen J, Bettaieb A, Haj FG, Ley RE, Chouinard ML, Cummings BP. TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice. Gut. 2017 02; 66(2):226-234. PMID: 26511794.
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    25. Bettaieb A, Hosein E, Chahed S, Abdulaziz A, Kucera HR, Gaikwad NW, Haj FG. Decreased adiposity and enhanced glucose tolerance in shikonin treated mice. Obesity (Silver Spring). 2015 Nov; 23(11):2269-77. PMID: 26374090.
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    26. Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9082-7. PMID: 26150506.
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    27. Bettaieb A, Chahed S, Bachaalany S, Griffey S, Hammock BD, Haj FG. Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. Mol Pharmacol. 2015 Aug; 88(2):281-90. PMID: 25993999.
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    28. Jialal I, Devaraj S, Bettaieb A, Haj F, Adams-Huet B. Increased adipose tissue secretion of Fetuin-A, lipopolysaccharide-binding protein and high-mobility group box protein 1 in metabolic syndrome. Atherosclerosis. 2015 Jul; 241(1):130-7. PMID: 25978344.
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    29. Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schröder K, Shah A, Brandes RP, Haj FG, Török NJ. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. Gastroenterology. 2015 Aug; 149(2):468-80.e10. PMID: 25888330.
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    30. Harris TR, Bettaieb A, Kodani S, Dong H, Myers R, Chiamvimonvat N, Haj FG, Hammock BD. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):102-11. PMID: 25827057.
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    31. Vazquez Prieto MA, Bettaieb A, Rodriguez Lanzi C, Soto VC, Perdicaro DJ, Galmarini CR, Haj FG, Miatello RM, Oteiza PI. Catechin and quercetin attenuate adipose inflammation in fructose-fed rats and 3T3-L1 adipocytes. Mol Nutr Food Res. 2015 Apr; 59(4):622-33. PMID: 25620282.
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    32. Bettaieb A, Morisseau C, Hammock B, Haj F. Soluble epoxide hydrolase deficiency ameliorates acute pancreatitis in mice. Free Radic Biol Med. 2014 Oct; 75 Suppl 1:S32. PMID: 26461340.
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    33. Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. PLoS One. 2014; 9(11):e113019. PMID: 25402489.
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    34. Xi Y, Liu S, Bettaieb A, Matsuo K, Matsuo I, Hosein E, Chahed S, Wiede F, Zhang S, Zhang ZY, Kulkarni RN, Tiganis T, Haj FG. Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice. Diabetologia. 2015 Jan; 58(1):122-31. PMID: 25338551.
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    35. Bakke J, Haj FG. Protein-tyrosine phosphatase 1B substrates and metabolic regulation. Semin Cell Dev Biol. 2015 Jan; 37:58-65. PMID: 25263014.
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    36. Tomilov A, Bettaieb A, Kim K, Sahdeo S, Tomilova N, Lam A, Hagopian K, Connell M, Fong J, Rowland D, Griffey S, Ramsey J, Haj F, Cortopassi G. Shc depletion stimulates brown fat activity in vivo and in vitro. Aging Cell. 2014 Dec; 13(6):1049-58. PMID: 25257068.
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    37. Borkowski K, Wrzesinski K, Rogowska-Wrzesinska A, Audouze K, Bakke J, Petersen RK, Haj FG, Madsen L, Kristiansen K. Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes. Biochim Biophys Acta. 2014 Dec; 1844(12):2096-107. PMID: 25152230.
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    38. Liu S, Xi Y, Bettaieb A, Matsuo K, Matsuo I, Kulkarni RN, Haj FG. Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects ß-cell function. Endocrinology. 2014 Sep; 155(9):3329-38. PMID: 24956127.
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    39. Fjære E, Aune UL, Røen K, Keenan AH, Ma T, Borkowski K, Kristensen DM, Novotny GW, Mandrup-Poulsen T, Hudson BD, Milligan G, Xi Y, Newman JW, Haj FG, Liaset B, Kristiansen K, Madsen L. Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice. J Biol Chem. 2014 Jun 06; 289(23):16032-45. PMID: 24742673.
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    40. Bettaieb A, Vazquez Prieto MA, Rodriguez Lanzi C, Miatello RM, Haj FG, Fraga CG, Oteiza PI. (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. Free Radic Biol Med. 2014 Jul; 72:247-56. PMID: 24746618.
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    41. Cummings BP, Bettaieb A, Graham JL, Stanhope K, Haj FG, Havel PJ. Administration of pioglitazone alone or with alogliptin delays diabetes onset in UCD-T2DM rats. J Endocrinol. 2014 Apr; 221(1):133-44. PMID: 24627447.
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    42. Bettaieb A, Xi Y, Hosein E, Coggins N, Bachaalany S, Wiede F, Perez S, Griffey SM, Sastre J, Tiganis T, Haj FG. Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis. Cell Commun Signal. 2014 Mar 10; 12:13. PMID: 24606867.
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    43. Warden CH, Slupsky C, Griffey SM, Bettaieb A, Min E, Le A, Fisler JS, Hansen S, Haj F, Stern JS. Brown Norway chromosome 1 congenic reduces symptoms of renal disease in fatty Zucker rats. PLoS One. 2014; 9(1):e87770. PMID: 24498189.
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    44. Wang YI, Bettaieb A, Sun C, DeVerse JS, Radecke CE, Mathew S, Edwards CM, Haj FG, Passerini AG, Simon SI. Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS One. 2013; 8(10):e78322. PMID: 24205197.
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    45. Bakke J, Bettaieb A, Nagata N, Matsuo K, Haj FG. Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B. Cell Commun Signal. 2013 Aug 12; 11:57. PMID: 23937695.
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    46. Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG. Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation. J Biol Chem. 2013 Jun 14; 288(24):17360-71. PMID: 23640882.
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    47. Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem. 2013 May 17; 288(20):14189-99. PMID: 23576437.
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    48. Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH. Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity. Am J Physiol Endocrinol Metab. 2013 Jun 01; 304(11):E1175-87. PMID: 23512805.
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    49. Yannan Xi, Fawaz G. Haj. Protein-Tyrosine Phosphatase 1B Substrates and Control of Metabolism. 2013 Jan 1; 49-69.
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    50. Cummings BP, Bettaieb A, Graham JL, Kim J, Ma F, Shibata N, Stanhope KL, Giulivi C, Hansen F, Jelsing J, Vrang N, Kowala M, Chouinard ML, Haj FG, Havel PJ. Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats. Dis Model Mech. 2013 Mar; 6(2):443-56. PMID: 23264565.
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    51. Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11390-5. PMID: 22733772.
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    52. Cummings BP, Bettaieb A, Graham JL, Stanhope KL, Kowala M, Haj FG, Chouinard ML, Havel PJ. Vertical sleeve gastrectomy improves glucose and lipid metabolism and delays diabetes onset in UCD-T2DM rats. Endocrinology. 2012 Aug; 153(8):3620-32. PMID: 22719048.
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    53. Haj FG, Sabet O, Kinkhabwala A, Wimmer-Kleikamp S, Roukos V, Han HM, Grabenbauer M, Bierbaum M, Antony C, Neel BG, Bastiaens PI. Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B. PLoS One. 2012; 7(5):e36633. PMID: 22655028.
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    54. Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG. Hepatic Src homology phosphatase 2 regulates energy balance in mice. Endocrinology. 2012 Jul; 153(7):3158-69. PMID: 22619361.
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    55. Bettaieb A, Matsuo K, Matsuo I, Wang S, Melhem R, Koromilas AE, Haj FG. Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2a signaling in brown adipocytes. PLoS One. 2012; 7(4):e34412. PMID: 22509299.
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    56. Vazquez-Prieto MA, Bettaieb A, Haj FG, Fraga CG, Oteiza PI. (-)-Epicatechin prevents TNFa-induced activation of signaling cascades involved in inflammation and insulin sensitivity in 3T3-L1 adipocytes. Arch Biochem Biophys. 2012 Nov 15; 527(2):113-8. PMID: 22425757.
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    57. Cummings BP, Bettaieb A, Graham JL, Stanhope KL, Dill R, Morton GJ, Haj FG, Havel PJ. Subcutaneous administration of leptin normalizes fasting plasma glucose in obese type 2 diabetic UCD-T2DM rats. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14670-5. PMID: 21873226.
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    58. Luria A, Bettaieb A, Xi Y, Shieh GJ, Liu HC, Inoue H, Tsai HJ, Imig JD, Haj FG, Hammock BD. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9038-43. PMID: 21571638.
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    59. Bettaieb A, Matsuo K, Matsuo I, Nagata N, Chahed S, Liu S, Haj FG. Adipose-specific deletion of Src homology phosphatase 2 does not significantly alter systemic glucose homeostasis. Metabolism. 2011 Aug; 60(8):1193-201. PMID: 21353259.
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    60. Matsuo K, Bettaieb A, Nagata N, Matsuo I, Keilhack H, Haj FG. Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B. PLoS One. 2011 Jan 31; 6(1):e16446. PMID: 21305007.
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    61. Bettaieb A, Liu S, Xi Y, Nagata N, Matsuo K, Matsuo I, Chahed S, Bakke J, Keilhack H, Tiganis T, Haj FG. Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase. J Biol Chem. 2011 Mar 18; 286(11):9225-35. PMID: 21216966.
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    62. Nievergall E, Janes PW, Stegmayer C, Vail ME, Haj FG, Teng SW, Neel BG, Bastiaens PI, Lackmann M. PTP1B regulates Eph receptor function and trafficking. J Cell Biol. 2010 Dec 13; 191(6):1189-203. PMID: 21135139.
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    63. Matsuo K, Delibegovic M, Matsuo I, Nagata N, Liu S, Bettaieb A, Xi Y, Araki K, Yang W, Kahn BB, Neel BG, Haj FG. Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2. J Biol Chem. 2010 Dec 17; 285(51):39750-8. PMID: 20841350.
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    64. Xue B, Pulinilkunnil T, Murano I, Bence KK, He H, Minokoshi Y, Asakura K, Lee A, Haj F, Furukawa N, Catalano KJ, Delibegovic M, Balschi JA, Cinti S, Neel BG, Kahn BB. Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues. Mol Cell Biol. 2009 Aug; 29(16):4563-73. PMID: 19528236.
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    65. Dadke S, Cotteret S, Yip SC, Jaffer ZM, Haj F, Ivanov A, Rauscher F, Shuai K, Ng T, Neel BG, Chernoff J. Regulation of protein tyrosine phosphatase 1B by sumoylation. Nat Cell Biol. 2007 Jan; 9(1):80-5. PMID: 17159996.
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    66. Arias-Salgado EG, Haj F, Dubois C, Moran B, Kasirer-Friede A, Furie BC, Furie B, Neel BG, Shattil SJ. PTP-1B is an essential positive regulator of platelet integrin signaling. J Cell Biol. 2005 Aug 29; 170(5):837-45. PMID: 16115959.
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    67. Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG. Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice. J Biol Chem. 2005 Apr 15; 280(15):15038-46. PMID: 15699041.
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    68. Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T. Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Mol Cell Biol. 2005 Jan; 25(2):819-29. PMID: 15632081.
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    69. Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem. 2004 Jun 04; 279(23):24844-51. PMID: 15031294.
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    70. Persson C, Sävenhed C, Bourdeau A, Tremblay ML, Markova B, Böhmer FD, Haj FG, Neel BG, Elson A, Heldin CH, Rönnstrand L, Ostman A, Hellberg C. Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase. Mol Cell Biol. 2004 Mar; 24(5):2190-201. PMID: 14966296.
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    71. Kushner JA, Haj FG, Klaman LD, Dow MA, Kahn BB, Neel BG, White MF. Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice. Diabetes. 2004 Jan; 53(1):61-6. PMID: 14693698.
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    72. Sajnani-Perez G, Chilton JK, Aricescu AR, Haj F, Stoker AW. Isoform-specific binding of the tyrosine phosphatase PTPsigma to a ligand in developing muscle. Mol Cell Neurosci. 2003 Jan; 22(1):37-48. PMID: 12595237.
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    73. Haj FG, Markova B, Klaman LD, Bohmer FD, Neel BG. Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B. J Biol Chem. 2003 Jan 10; 278(2):739-44. PMID: 12424235.
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    74. Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG. PTP1B regulates leptin signal transduction in vivo. Dev Cell. 2002 Apr; 2(4):489-95. PMID: 11970898.
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    75. Haj FG, Verveer PJ, Squire A, Neel BG, Bastiaens PI. Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Science. 2002 Mar 01; 295(5560):1708-11. PMID: 11872838.
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    76. Ledig MM, Haj F, Bixby JL, Stoker AW, Mueller BK. The receptor tyrosine phosphatase CRYPalpha promotes intraretinal axon growth. J Cell Biol. 1999 Oct 18; 147(2):375-88. PMID: 10525542.
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    77. Haj F, McKinnell I, Stoker A. Retinotectal ligands for the receptor tyrosine phosphatase CRYPalpha. Mol Cell Neurosci. 1999 Sep; 14(3):225-40. PMID: 10493824.
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    78. Stoker AW, Gehrig B, Haj F, Bay BH. Axonal localisation of the CAM-like tyrosine phosphatase CRYP alpha: a signalling molecule of embryonic growth cones. Development. 1995 Jun; 121(6):1833-44. PMID: 7600997.
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