Xiaodong Zhang

Title(s)Associate Adjunct Professor, MED: Int Med Cardiology (Sac)
SchoolSchool of Medicine
AddressGBSF
CA 95616
Phone530-752-9717
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2. Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39):e2318900121. Woltz RL, Zheng Y, Choi W, Ngo K, Trinh P, Ren L, Thai PN, Harris BJ, Han Y, Rouen KC, Mateos DL, Jian Z, Chen-Izu Y, Dickson EJ, Yamoah EN, Yarov-Yarovoy V, Vorobyov I, Zhang XD, Chiamvimonvat N. PMID: 39288178; PMCID: PMC11441529.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Association of Neighborhood and Environmental Factors With Clinical Phenotypes and Outcomes in Heart Failure With Preserved Ejection Fraction. Circ Res. 2024 Jun 21; 135(1):155-158. Liem DA, Silva H, Romero E, Rocha P, Acevedo PE, Izu MR, Ballal A, Soroya M, López JE, Nuno MA, Quazi A, Mukherjee C, Linklater W, Ebong I, Zhang XD, Izu LT, Sirish P, Chiamvimonvat N, Cadeiras M. PMID: 38759107; PMCID: PMC11189721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell. Nat Commun. 2024 Jan 16; 15(1):526. Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz RL, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. PMID: 38228630; PMCID: PMC10791687.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Targeting Small-Conductance Calcium-Activated Potassium Channels in Atrial Fibrillation: Therapeutic Opportunities. Circ Res. 2023 04 28; 132(9):1104-1106. Zhang XD, Chiamvimonvat N. PMID: 37104564; PMCID: PMC10155264.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains. JCI Insight. 2022 11 22; 7(22). Ren L, Thai PN, Gopireddy RR, Timofeyev V, Ledford HA, Woltz RL, Park S, Puglisi JL, Moreno CM, Santana LF, Conti AC, Kotlikoff MI, Xiang YK, Yarov-Yarovoy V, Zaccolo M, Zhang XD, Yamoah EN, Navedo MF, Chiamvimonvat N. PMID: 36509290; PMCID: PMC9746826.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    6. Disruption of mitochondria-sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2206708119. Ren L, Gopireddy RR, Perkins G, Zhang H, Timofeyev V, Lyu Y, Diloretto DA, Trinh P, Sirish P, Overton JL, Xu W, Grainger N, Xiang YK, Dedkova EN, Zhang XD, Yamoah EN, Navedo MF, Thai PN, Chiamvimonvat N. PMID: 36044551; PMCID: PMC9456763.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    7. Protocol to record and quantify the intracellular pH in contracting cardiomyocytes. STAR Protoc. 2022 06 17; 3(2):101301. Lyu Y, Timofeyev V, Overton J, Thai PN, Yamoah EN, Chiamvimonvat N, Zhang XD. PMID: 35463464; PMCID: PMC9026584.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Beat-to-beat dynamic regulation of intracellular pH in cardiomyocytes. iScience. 2022 Jan 21; 25(1):103624. Lyu Y, Thai PN, Ren L, Timofeyev V, Jian Z, Park S, Ginsburg KS, Overton J, Bossuyt J, Bers DM, Yamoah EN, Chen-Izu Y, Chiamvimonvat N, Zhang XD. PMID: 35005560; PMCID: PMC8718820.
      View in: PubMed   Mentions: 5  
    9. Protocol to assess two distinct components of the nonlinear capacitance in mouse cardiomyocytes. STAR Protoc. 2021 12 17; 2(4):100891. Zhang XD, Flores MCP, Timofeyev V, Yamoah EN, Chiamvimonvat N. PMID: 34704077; PMCID: PMC8521203.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    10. Disruption of protein quality control of the human ether-à-go-go related gene K+ channel results in profound long QT syndrome. Heart Rhythm. 2022 02; 19(2):281-292. Ledford HA, Ren L, Thai PN, Park S, Timofeyev V, Sirish P, Xu W, Emigh AM, Priest JR, Perez MV, Ashley EA, Yarov-Yarovoy V, Yamoah EN, Zhang XD, Chiamvimonvat N. PMID: 34634443; PMCID: PMC8810706.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    11. Model Systems for Addressing Mechanism of Arrhythmogenesis in Cardiac Repair. Curr Cardiol Rep. 2021 05 29; 23(6):72. Zhang XD, Thai PN, Lieu DK, Chiamvimonvat N. PMID: 34050853; PMCID: PMC8164614.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Prestin amplifies cardiac motor functions. Cell Rep. 2021 05 04; 35(5):109097. Zhang XD, Thai PN, Ren L, Perez Flores MC, Ledford HA, Park S, Lee JH, Sihn CR, Chang CW, Chen WC, Timofeyev V, Zuo J, Chan JW, Yamoah EN, Chiamvimonvat N. PMID: 33951436; PMCID: PMC8720583.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    13. Transgene Delivery to Human Induced Pluripotent Stem Cells Using Nanoparticles. Pharmaceuticals (Basel). 2021 Apr 06; 14(4). Yamoah MA, Thai PN, Zhang XD. PMID: 33917388; PMCID: PMC8067386.
      View in: PubMed   Mentions: 2  
    14. Cardiac small-conductance calcium-activated potassium channels in health and disease. Pflugers Arch. 2021 03; 473(3):477-489. Zhang XD, Thai PN, Lieu DK, Chiamvimonvat N. PMID: 33624131; PMCID: PMC7940285.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    15. Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation. J Gen Physiol. 2020 12 07; 152(12). Ledford HA, Park S, Muir D, Woltz RL, Ren L, Nguyen PT, Sirish P, Wang W, Sihn CR, George AL, Knollmann BC, Yamoah EN, Yarov-Yarovoy V, Zhang XD, Chiamvimonvat N. PMID: 33211795; PMCID: PMC7681919.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells. Stem Cell Res. 2020 12; 49:102043. Yechikov S, Kao HKJ, Chang CW, Pretto D, Zhang XD, Sun YH, Smithers R, Sirish P, Nolta JA, Chan JW, Chiamvimonvat N, Lieu DK. PMID: 33128951; PMCID: PMC7814970.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    17. Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy. Stem Cells Transl Med. 2020 12; 9(12):1570-1584. Sirish P, Thai PN, Lee JH, Yang J, Zhang XD, Ren L, Li N, Timofeyev V, Lee KSS, Nader CE, Rowland DJ, Yechikov S, Ganaga S, Young N, Lieu DK, Yamoah EN, Hammock BD, Chiamvimonvat N. PMID: 32790136; PMCID: PMC7695637.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Cooperativity of Kv7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells. Sci Adv. 2020 04; 6(15):eaba1104. Perez-Flores MC, Lee JH, Park S, Zhang XD, Sihn CR, Ledford HA, Wang W, Kim HJ, Timofeyev V, Yarov-Yarovoy V, Chiamvimonvat N, Rabbitt RD, Yamoah EN. PMID: 32285007; PMCID: PMC7141818.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    19. The local translation of KNa in dendritic projections of auditory neurons and the roles of KNa in the transition from hidden to overt hearing loss. Aging (Albany NY). 2019 12 08; 11(23):11541-11564. Lee JH, Kang M, Park S, Perez-Flores MC, Zhang XD, Wang W, Gratton MA, Chiamvimonvat N, Yamoah EN. PMID: 31812952; PMCID: PMC6932877.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    20. Highly efficient transfection of human induced pluripotent stem cells using magnetic nanoparticles. Int J Nanomedicine. 2018; 13:6073-6078. Yamoah MA, Moshref M, Sharma J, Chen WC, Ledford HA, Lee JH, Chavez KS, Wang W, López JE, Lieu DK, Sirish P, Zhang XD. PMID: 30323594; PMCID: PMC6179720.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    21. Coupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes. Sci Rep. 2018 03 16; 8(1):4670. Zhang XD, Coulibaly ZA, Chen WC, Ledford HA, Lee JH, Sirish P, Dai G, Jian Z, Chuang F, Brust-Mascher I, Yamoah EN, Chen-Izu Y, Izu LT, Chiamvimonvat N. PMID: 29549309; PMCID: PMC5856806.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    22. Action Potential Shortening and Impairment of Cardiac Function by Ablation of Slc26a6. Circ Arrhythm Electrophysiol. 2017 Oct; 10(10). Sirish P, Ledford HA, Timofeyev V, Thai PN, Ren L, Kim HJ, Park S, Lee JH, Dai G, Moshref M, Sihn CR, Chen WC, Timofeyeva MV, Jian Z, Shimkunas R, Izu LT, Chiamvimonvat N, Chen-Izu Y, Yamoah EN, Zhang XD. PMID: 29025768; PMCID: PMC5662469.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    23. Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans. Sci Rep. 2017 03 13; 7(1):169. O'Halloran DM, Altshuler-Keylin S, Zhang XD, He C, Morales-Phan C, Yu Y, Kaye JA, Brueggemann C, Chen TY, L'Etoile ND. PMID: 28279024; PMCID: PMC5427828.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    24. Distinct subcellular mechanisms for the enhancement of the surface membrane expression of SK2 channel by its interacting proteins, α-actinin2 and filamin A. J Physiol. 2017 04 01; 595(7):2271-2284. Zhang Z, Ledford HA, Park S, Wang W, Rafizadeh S, Kim HJ, Xu W, Lu L, Lau VC, Knowlton AA, Zhang XD, Yamoah EN, Chiamvimonvat N. PMID: 27779751; PMCID: PMC5374114.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    25. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. PMID: 27162031; PMCID: PMC4869994.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    26. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. J Mol Cell Cardiol. 2016 05; 94:180-188. Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. PMID: 27079253; PMCID: PMC4972711.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. Mechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ Channels. J Biol Chem. 2016 Jan 29; 291(5):2499-509. Sihn CR, Kim HJ, Woltz RL, Yarov-Yarovoy V, Yang PC, Xu J, Clancy CE, Zhang XD, Chiamvimonvat N, Yamoah EN. PMID: 26515070; PMCID: PMC4732230.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    28. Feedback mechanisms for cardiac-specific microRNAs and cAMP signaling in electrical remodeling. Circ Arrhythm Electrophysiol. 2015 Aug; 8(4):942-50. Myers R, Timofeyev V, Li N, Kim C, Ledford HA, Sirish P, Lau V, Zhang Y, Fayyaz K, Singapuri A, Lopez JE, Knowlton AA, Zhang XD, Chiamvimonvat N. PMID: 25995211; PMCID: PMC4545299.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    29. Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias. Heart Rhythm. 2015 Aug; 12(8):1845-51. Zhang XD, Lieu DK, Chiamvimonvat N. PMID: 25956967; PMCID: PMC4662728.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    30. Identification of a key residue in Kv7.1 potassium channel essential for sensing external potassium ions. J Gen Physiol. 2015 Mar; 145(3):201-12. Wang W, Flores MC, Sihn CR, Kim HJ, Zhang Y, Doyle KJ, Chiamvimonvat N, Zhang XD, Yamoah EN. PMID: 25712016; PMCID: PMC4338162.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    31. Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16A. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2575-80. Zhang XD, Lee JH, Lv P, Chen WC, Kim HJ, Wei D, Wang W, Sihn CR, Doyle KJ, Rock JR, Chiamvimonvat N, Yamoah EN. PMID: 25675481; PMCID: PMC4345570.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    32. Regulation of gene transcription by voltage-gated L-type calcium channel, Cav1.3. J Biol Chem. 2015 Feb 20; 290(8):4663-4676. Lu L, Sirish P, Zhang Z, Woltz RL, Li N, Timofeyev V, Knowlton AA, Zhang XD, Yamoah EN, Chiamvimonvat N. PMID: 25538241; PMCID: PMC4335206.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    33. Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons. J Neurosci. 2014 May 21; 34(21):7383-93. Lv P, Kim HJ, Lee JH, Sihn CR, Fathabad Gharaie S, Mousavi-Nik A, Wang W, Wang HG, Gratton MA, Doyle KJ, Zhang XD, Chiamvimonvat N, Yamoah EN. PMID: 24849370; PMCID: PMC4028507.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    34. Critical roles of a small conductance Ca²⁺-activated K⁺ channel (SK3) in the repolarization process of atrial myocytes. Cardiovasc Res. 2014 Feb 01; 101(2):317-25. Zhang XD, Timofeyev V, Li N, Myers RE, Zhang DM, Singapuri A, Lau VC, Bond CT, Adelman J, Lieu DK, Chiamvimonvat N. PMID: 24282291; PMCID: PMC3896251.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    35. Slc26a6 functions as an electrogenic Cl-/HCO3- exchanger in cardiac myocytes. Cardiovasc Res. 2013 Dec 01; 100(3):383-91. Kim HJ, Myers R, Sihn CR, Rafizadeh S, Zhang XD. PMID: 23933580.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    36. Synchronization modulation increases transepithelial potentials in MDCK monolayers through Na/K pumps. PLoS One. 2013; 8(4):e61509. Tran V, Zhang X, Cao L, Li H, Lee B, So M, Sun Y, Chen W, Zhao M. PMID: 23585907; PMCID: PMC3621860.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    37. Myotonia congenita mutation enhances the degradation of human CLC-1 chloride channels. PLoS One. 2013; 8(2):e55930. Lee TT, Zhang XD, Chuang CC, Chen JJ, Chen YA, Chen SC, Chen TY, Tang CY. PMID: 23424641; PMCID: PMC3570542.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    38. Different roles of membrane potentials in electrotaxis and chemotaxis of dictyostelium cells. Eukaryot Cell. 2011 Sep; 10(9):1251-6. Gao RC, Zhang XD, Sun YH, Kamimura Y, Mogilner A, Devreotes PN, Zhao M. PMID: 21743003; PMCID: PMC3187056.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    39. Binding of ATP to the CBS domains in the C-terminal region of CLC-1. J Gen Physiol. 2011 Apr; 137(4):357-68. Tseng PY, Yu WP, Liu HY, Zhang XD, Zou X, Chen TY. PMID: 21444658; PMCID: PMC3068280.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    40. Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas. Brain Res. 2010 Dec 02; 1363:159-69. Harley W, Floyd C, Dunn T, Zhang XD, Chen TY, Hegde M, Palandoken H, Nantz MH, Leon L, Carraway KL, Lyeth B, Gorin FA. PMID: 20869350; PMCID: PMC2996276.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    41. Chloride channels and transporters in human corneal epithelium. Exp Eye Res. 2010 Jun; 90(6):771-9. Cao L, Zhang XD, Liu X, Chen TY, Zhao M. PMID: 20346358; PMCID: PMC2873124.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    42. Accessibility of the CLC-0 pore to charged methanethiosulfonate reagents. Biophys J. 2010 Feb 03; 98(3):377-85. Zhang XD, Yu WP, Chen TY. PMID: 20141750; PMCID: PMC2814198.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    43. Amphiphilic blockers punch through a mutant CLC-0 pore. J Gen Physiol. 2009 Jan; 133(1):59-68. Zhang XD, Chen TY. PMID: 19088382; PMCID: PMC2606939.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    44. Blocking pore-open mutants of CLC-0 by amphiphilic blockers. J Gen Physiol. 2009 Jan; 133(1):43-58. Zhang XD, Tseng PY, Yu WP, Chen TY. PMID: 19088381; PMCID: PMC2606940.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    45. ATP inhibition of CLC-1 is controlled by oxidation and reduction. J Gen Physiol. 2008 Oct; 132(4):421-8. Zhang XD, Tseng PY, Chen TY. PMID: 18824589; PMCID: PMC2553389.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    46. Large movement in the C terminus of CLC-0 chloride channel during slow gating. Nat Struct Mol Biol. 2006 Dec; 13(12):1115-9. Bykova EA, Zhang XD, Chen TY, Zheng J. PMID: 17115052.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    47. Roles of K149, G352, and H401 in the channel functions of ClC-0: testing the predictions from theoretical calculations. J Gen Physiol. 2006 Apr; 127(4):435-47. Zhang XD, Li Y, Yu WP, Chen TY. PMID: 16567465; PMCID: PMC2151512.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    48. Expression of novel isoforms of the CIC-1 chloride channel in astrocytic glial cells in vitro. Glia. 2004 Jul; 47(1):46-57. Zhang XD, Morishima S, Ando-Akatsuka Y, Takahashi N, Nabekura T, Inoue H, Shimizu T, Okada Y. PMID: 15139012.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    Xiaodong's Networks
    Concepts (270)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (38)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UC Davis Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-6-g69de2244 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California