Yang Kevin Xiang

Title(s)Professor, Pharmacology
SchoolSchool of Medicine
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    1. Loss of Myeloid Cell-Specific β2-Adrenergic Receptor Expression Ameliorates Cardiac Function and Remodeling after Acute Ischemia. bioRxiv. 2023 Nov 27. Nayak TK, Bajpai A, Patwa V, Carter RL, Enjamuri N, Gao E, Xiang YK, Tilley DG. PMID: 38076917; PMCID: PMC10705241.
      View in: PubMed   Mentions:
    2. Phosphodiesterase in heart and vessels: from physiology to diseases. Physiol Rev. 2024 Apr 01; 104(2):765-834. Fu Q, Wang Y, Yan C, Xiang YK. PMID: 37971403.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis. Cells. 2023 06 19; 12(12). Lu P, Zhang D, Ding F, Ma J, Xiang YK, Zhao M. PMID: 37371137; PMCID: PMC10297193.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Transfer of nuclear and ribosomal material from Sox10-lineage cells to neurons in the mouse brain. J Exp Med. 2023 07 03; 220(7). Mayrhofer F, Hanson AM, Navedo MF, Xiang YK, Soulika AM, Deng W, Chechneva OV. PMID: 37067791; PMCID: PMC10114922.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced nuclear cAMP signaling required for learning and memory. Sci Signal. 2023 03 28; 16(778):eade3380. Martinez JM, Shen A, Xu B, Jovanovic A, de Chabot J, Zhang J, Xiang YK. PMID: 36976866; PMCID: PMC10404024.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein. Proc Natl Acad Sci U S A. 2023 03 07; 120(10):e2215916120. Han Y, Dawson JRD, DeMarco KR, Rouen KC, Bekker S, Yarov-Yarovoy V, Clancy CE, Xiang YK, Vorobyov I. PMID: 36853938; PMCID: PMC10013855.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    7. Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart. JACC Basic Transl Sci. 2023 Jun; 8(6):638-655. Jovanovic A, Xu B, Zhu C, Ren D, Wang H, Krause-Hauch M, Abel ED, Li J, Xiang YK. PMID: 37426525; PMCID: PMC10322917.
      View in: PubMed   Mentions: 1  
    8. Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics. Sci Adv. 2023 01 20; 9(3):eadd5799. Caldwell JL, Lee IJ, Ngo L, Wang L, Bahriz S, Xu B, Bers DM, Navedo MF, Bossuyt J, Xiang YK, Ripplinger CM. PMID: 36662864; PMCID: PMC9858506.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. Divergent Actions of Myofibroblast and Myocyte β2-Adrenoceptor in Heart Failure and Fibrotic Remodeling. Circ Res. 2023 01 06; 132(1):106-108. Deng B, Zhang Y, Zhu C, Wang Y, Weatherford E, Xu B, Liu X, Conway SJ, Abel ED, Xiang YK. PMID: 36458552; PMCID: PMC9985902.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    10. Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains. JCI Insight. 2022 11 22; 7(22). Ren L, Thai PN, Gopireddy RR, Timofeyev V, Ledford HA, Woltz RL, Park S, Puglisi JL, Moreno CM, Santana LF, Conti AC, Kotlikoff MI, Xiang YK, Yarov-Yarovoy V, Zaccolo M, Zhang XD, Yamoah EN, Navedo MF, Chiamvimonvat N. PMID: 36509290; PMCID: PMC9746826.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    11. Probing spatiotemporal PKA activity at the ryanodine receptor and SERCA2a nanodomains in cardomyocytes. Cell Commun Signal. 2022 09 14; 20(1):143. Xu B, Wang Y, Bahriz SMFM, Zhao M, Zhu C, Xiang YK. PMID: 36104752; PMCID: PMC9472443.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    12. Disruption of mitochondria-sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2206708119. Ren L, Gopireddy RR, Perkins G, Zhang H, Timofeyev V, Lyu Y, Diloretto DA, Trinh P, Sirish P, Overton JL, Xu W, Grainger N, Xiang YK, Dedkova EN, Zhang XD, Yamoah EN, Navedo MF, Thai PN, Chiamvimonvat N. PMID: 36044551; PMCID: PMC9456763.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. Monoamine oxidase A and organic cation transporter 3 coordinate intracellular β1AR signaling to calibrate cardiac contractile function. Basic Res Cardiol. 2022 07 17; 117(1):37. Wang Y, Zhao M, Xu B, Bahriz SMF, Zhu C, Jovanovic A, Ni H, Jacobi A, Kaludercic N, Di Lisa F, Hell JW, Shih JC, Paolocci N, Xiang YK. PMID: 35842861; PMCID: PMC9288959.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Subcellular Propagation of Cardiomyocyte β-Adrenergic Activation of Calcium Uptake Involves Internal β-Receptors and AKAP7. Function (Oxf). 2022; 3(3):zqac020. Shannon TR, Bare DJ, Van Dijk S, Raofi S, Huynh TN, Xiang YK, Bossuyt J, Dodge-Kafka KL, Ginsburg KS, Bers DM. PMID: 35620477; PMCID: PMC9125612.
      View in: PubMed   Mentions: 4     Fields:    
    15. Gα12 and Gα13: Versatility in Physiology and Pathology. Front Cell Dev Biol. 2022; 10:809425. Guo P, Tai Y, Wang M, Sun H, Zhang L, Wei W, Xiang YK, Wang Q. PMID: 35237598; PMCID: PMC8883321.
      View in: PubMed   Mentions: 2  
    16. Deciphering cellular signals in adult mouse sinoatrial node cells. iScience. 2022 Jan 21; 25(1):103693. Reddy GR, Ren L, Thai PN, Caldwell JL, Zaccolo M, Bossuyt J, Ripplinger CM, Xiang YK, Nieves-Cintrón M, Chiamvimonvat N, Navedo MF. PMID: 35036877; PMCID: PMC8749457.
      View in: PubMed   Mentions: 4  
    17. Monoamine Oxidases Desensitize Intracellular β1AR Signaling in Heart Failure. Circ Res. 2021 10 29; 129(10):965-967. Wang Y, Zhao M, Shi Q, Xu B, Zhu C, Li M, Mir V, Bers DM, Xiang YK. PMID: 34530626; PMCID: PMC8556367.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    18. Carvedilol induces biased β1 adrenergic receptor-nitric oxide synthase 3-cyclic guanylyl monophosphate signalling to promote cardiac contractility. Cardiovasc Res. 2021 08 29; 117(10):2237-2251. Wang Q, Wang Y, West TM, Liu Y, Reddy GR, Barbagallo F, Xu B, Shi Q, Deng B, Wei W, Xiang YK. PMID: 32956449; PMCID: PMC8502477.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility. Circ Res. 2021 01 22; 128(2):246-261. Wang Y, Shi Q, Li M, Zhao M, Reddy Gopireddy R, Teoh JP, Xu B, Zhu C, Ireton KE, Srinivasan S, Chen S, Gasser PJ, Bossuyt J, Hell JW, Bers DM, Xiang YK. PMID: 33183171; PMCID: PMC7856104.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    20. AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2. Nat Commun. 2020 10 20; 11(1):5303. Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, Navedo MF, Nieves-Cintrón M. PMID: 33082339; PMCID: PMC7575592.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    21. GRK5 Controls SAP97-Dependent Cardiotoxic β1 Adrenergic Receptor-CaMKII Signaling in Heart Failure. Circ Res. 2020 08 28; 127(6):796-810. Xu B, Li M, Wang Y, Zhao M, Morotti S, Shi Q, Wang Q, Barbagallo F, Teoh JP, Reddy GR, Bayne EF, Liu Y, Shen A, Puglisi JL, Ge Y, Li J, Grandi E, Nieves-Cintron M, Xiang YK. PMID: 32507058; PMCID: PMC7484403.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    22. Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice. Diabetes. 2020 06; 69(6):1292-1305. Sun X, Han F, Lu Q, Li X, Ren D, Zhang J, Han Y, Xiang YK, Li J. PMID: 32234722.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    23. Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling. JCI Insight. 2020 03 26; 5(6). Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. PMID: 32213702; PMCID: PMC7213803.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    24. Hyperinsulinemia promotes heterologous desensitization of β2 adrenergic receptor in airway smooth muscle in obesity. FASEB J. 2020 03; 34(3):3996-4008. Xu R, Gopireddy RR, Wu Y, Wu L, Tao X, Shao J, Wang W, Li L, Jovanovic A, Xu B, Kenyon NJ, Lu Q, Xiang YK, Fu Q. PMID: 31960515.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    25. β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons. Elife. 2019 10 14; 8. Shen A, Chen D, Kaur M, Bartels P, Xu B, Shi Q, Martinez JM, Man KM, Nieves-Cintron M, Hell JW, Navedo MF, Yu XY, Xiang YK. PMID: 31609201; PMCID: PMC6813027.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    26. A Myt1 family transcription factor defines neuronal fate by repressing non-neuronal genes. Elife. 2019 08 06; 8. Lee J, Taylor CA, Barnes KM, Shen A, Stewart EV, Chen A, Xiang YK, Bao Z, Shen K. PMID: 31386623; PMCID: PMC6684318.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    27. Correction to: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 Jul 26; 12(1):83. Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31349855; PMCID: PMC6660960.
      View in: PubMed   Mentions: 1     Fields:    
    28. Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts. J Am Heart Assoc. 2019 08 06; 8(15):e012273. West TM, Wang Q, Deng B, Zhang Y, Barbagallo F, Reddy GR, Chen D, Phan KS, Xu B, Isidori A, Xiang YK. PMID: 31311394; PMCID: PMC6761630.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    29. Whole-Cell cAMP and PKA Activity are Epiphenomena, Nanodomain Signaling Matters. Physiology (Bethesda). 2019 07 01; 34(4):240-249. Bers DM, Xiang YK, Zaccolo M. PMID: 31165682; PMCID: PMC6863374.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    30. High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 06 10; 12(1):56. Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31182116; PMCID: PMC6558829.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    31. Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia. J Clin Invest. 2019 06 04; 129(8):3140-3152. Syed AU, Reddy GR, Ghosh D, Prada MP, Nystoriak MA, Morotti S, Grandi E, Sirish P, Chiamvimonvat N, Hell JW, Santana LF, Xiang YK, Nieves-Cintrón M, Navedo MF. PMID: 31162142; PMCID: PMC6668679.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    32. β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes. J Physiol. 2019 04; 597(8):2139-2162. Ito DW, Hannigan KI, Ghosh D, Xu B, Del Villar SG, Xiang YK, Dickson EJ, Navedo MF, Dixon RE. PMID: 30714156; PMCID: PMC6462464.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    33. A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia. Elife. 2019 03 01; 8. Prada MP, Syed AU, Buonarati OR, Reddy GR, Nystoriak MA, Ghosh D, Simó S, Sato D, Sasse KC, Ward SM, Santana LF, Xiang YK, Hell JW, Nieves-Cintrón M, Navedo MF. PMID: 30821687; PMCID: PMC6397001.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    34. Illuminating cell signaling with genetically encoded FRET biosensors in adult mouse cardiomyocytes. J Gen Physiol. 2018 11 05; 150(11):1567-1582. Reddy GR, West TM, Jian Z, Jaradeh M, Shi Q, Wang Y, Chen-Izu Y, Xiang YK. PMID: 30242036; PMCID: PMC6219686.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    35. Profiling of Differential Expression of Genes in Mice Carrying Both Mutant Presenilin 1 and Amyloid Precursor Protein Transgenes with or without Knockout of B2 Adrenergic Receptor Gene. J Appl Bioinforma Comput Biol. 2018; 7(3). Zhou Y, Chen L, Zhou X, Pei Y, Wei S, Mehmood A, Xiang YK, Wang D. PMID: 31058201; PMCID: PMC6497178.
      View in: PubMed   Mentions: 1  
    36. The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival. Cell. 2018 09 06; 174(6):1436-1449.e20. Maeder CI, Kim JI, Liang X, Kaganovsky K, Shen A, Li Q, Li Z, Wang S, Xu XZS, Li JB, Xiang YK, Ding JB, Shen K. PMID: 30146163; PMCID: PMC6542560.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    37. A Dendritic Guidance Receptor Complex Brings Together Distinct Actin Regulators to Drive Efficient F-Actin Assembly and Branching. Dev Cell. 2018 05 07; 45(3):362-375.e3. Zou W, Dong X, Broederdorf TR, Shen A, Kramer DA, Shi R, Liang X, Miller DM, Xiang YK, Yasuda R, Chen B, Shen K. PMID: 29738713; PMCID: PMC6292511.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    38. Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem. 2018 04 26; 61(8):3541-3550. Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. PMID: 29614224; PMCID: PMC5933862.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    39. Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell. Nat Commun. 2018 03 13; 9(1):1050. Shen A, Nieves-Cintron M, Deng Y, Shi Q, Chowdhury D, Qi J, Hell JW, Navedo MF, Xiang YK. PMID: 29535304; PMCID: PMC5849717.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    40. Nanodelivery of a functional membrane receptor to manipulate cellular phenotype. Sci Rep. 2018 02 23; 8(1):3556. Patriarchi T, Shen A, He W, Baikoghli M, Cheng RH, Xiang YK, Coleman MA, Tian L. PMID: 29476125; PMCID: PMC5824837.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    41. β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease. Science. 2017 09 01; 357(6354):891-898. Mittal S, Bjørnevik K, Im DS, Flierl A, Dong X, Locascio JJ, Abo KM, Long E, Jin M, Xu B, Xiang YK, Rochet JC, Engeland A, Rizzu P, Heutink P, Bartels T, Selkoe DJ, Caldarone BJ, Glicksman MA, Khurana V, Schüle B, Park DS, Riise T, Scherzer CR. PMID: 28860381; PMCID: PMC5761666.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansAnimalsCells
    42. β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes. Sci Rep. 2017 08 11; 7(1):7890. Park M, Reddy GR, Wallukat G, Xiang YK, Steinberg SF. PMID: 28801655; PMCID: PMC5554155.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    43. Cross-Talk Between Insulin Signaling and G Protein-Coupled Receptors. J Cardiovasc Pharmacol. 2017 Aug; 70(2):74-86. Fu Q, Shi Q, West TM, Xiang YK. PMID: 28328746; PMCID: PMC5734060.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    44. Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes. Cardiovasc Res. 2017 May 01; 113(6):656-670. Shi Q, Li M, Mika D, Fu Q, Kim S, Phan J, Shen A, Vandecasteele G, Xiang YK. PMID: 28339772; PMCID: PMC5852637.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    45. Phosphodiesterase-5 inhibition preserves renal hemodynamics and function in mice with diabetic kidney disease by modulating miR-22 and BMP7. Sci Rep. 2017 03 15; 7:44584. Pofi R, Fiore D, De Gaetano R, Panio G, Gianfrilli D, Pozza C, Barbagallo F, Xiang YK, Giannakakis K, Morano S, Lenzi A, Naro F, Isidori AM, Venneri MA. PMID: 28294194; PMCID: PMC5353686.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    46. Insulin and β Adrenergic Receptor Signaling: Crosstalk in Heart. Trends Endocrinol Metab. 2017 06; 28(6):416-427. Fu Q, Wang Q, Xiang YK. PMID: 28256297; PMCID: PMC5535765.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. J Physiol. 2017 03 15; 595(6):1973-1986. Fu Q, Hu Y, Wang Q, Liu Y, Li N, Xu B, Kim S, Chiamvimonvat N, Xiang YK. PMID: 27983752; PMCID: PMC5350441.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    48. Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction. Circulation. 2017 Jan 03; 135(1):73-88. Wang Q, Liu Y, Fu Q, Xu B, Zhang Y, Kim S, Tan R, Barbagallo F, West T, Anderson E, Wei W, Abel ED, Xiang YK. PMID: 27815373; PMCID: PMC5302024.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    49. A multi-protein receptor-ligand complex underlies combinatorial dendrite guidance choices in C. elegans. Elife. 2016 10 05; 5. Zou W, Shen A, Dong X, Tugizova M, Xiang YK, Shen K. PMID: 27705746; PMCID: PMC5079751.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    50. With or Without Langendorff: A New Method for Adult Myocyte Isolation to Be Tested With Time. Circ Res. 2016 09 30; 119(8):888-90. Chen X, O'Connell TD, Xiang YK. PMID: 27688302; PMCID: PMC5361738.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    51. Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure. Circ Res. 2016 Sep 30; 119(8):931-43. Barbagallo F, Xu B, Reddy GR, West T, Wang Q, Fu Q, Li M, Shi Q, Ginsburg KS, Ferrier W, Isidori AM, Naro F, Patel HH, Bossuyt J, Bers D, Xiang YK. PMID: 27576469; PMCID: PMC5307331.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    52. Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins. Cell Signal. 2016 08; 28(8):1001-14. Skieterska K, Shen A, Clarisse D, Rondou P, Borroto-Escuela DO, Lintermans B, Fuxe K, Xiang YK, Van Craenenbroeck K. PMID: 27155323.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    53. Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor. EMBO J. 2016 06 15; 35(12):1330-45. Patriarchi T, Qian H, Di Biase V, Malik ZA, Chowdhury D, Price JL, Hammes EA, Buonarati OR, Westenbroek RE, Catterall WA, Hofmann F, Xiang YK, Murphy GG, Chen CY, Navedo MF, Hell JW. PMID: 27103070; PMCID: PMC4910527.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    54. Three Recombinant Engineered Antibodies against Recombinant Tags with High Affinity and Specificity. PLoS One. 2016; 11(3):e0150125. Zhao H, Shen A, Xiang YK, Corey DP. PMID: 26943906; PMCID: PMC4778845.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    55. Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Cell Stem Cell. 2015 Jul 02; 17(1):89-100. Wu H, Lee J, Vincent LG, Wang Q, Gu M, Lan F, Churko JM, Sallam KI, Matsa E, Sharma A, Gold JD, Engler AJ, Xiang YK, Bers DM, Wu JC. PMID: 26095046; PMCID: PMC4546705.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    56. Trafficking of β-Adrenergic Receptors: Implications in Intracellular Receptor Signaling. Prog Mol Biol Transl Sci. 2015; 132:151-88. Fu Q, Xiang YK. PMID: 26055058; PMCID: PMC7328190.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    57. Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes. Cardiovasc Res. 2015 Jun 01; 106(3):408-20. Isidori AM, Cornacchione M, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M, Naro F. PMID: 25852085.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    58. Insulin induces IRS2-dependent and GRK2-mediated β2AR internalization to attenuate βAR signaling in cardiomyocytes. Cell Signal. 2015 Mar; 27(3):707-15. Fu Q, Xu B, Parikh D, Cervantes D, Xiang YK. PMID: 25460042; PMCID: PMC4333100.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    59. A module of human peripheral blood mononuclear cell transcriptional network containing primitive and differentiation markers is related to specific cardiovascular health variables. PLoS One. 2014; 9(4):e95124. Moldovan L, Anghelina M, Kantor T, Jones D, Ramadan E, Xiang Y, Huang K, Kolipaka A, Malarkey W, Ghasemzadeh N, Mohler PJ, Quyyumi A, Moldovan NI. PMID: 24759906; PMCID: PMC3997360.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    60. A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes. J Biol Chem. 2014 May 23; 289(21):14771-81. Fu Q, Kim S, Soto D, De Arcangelis V, DiPilato L, Liu S, Xu B, Shi Q, Zhang J, Xiang YK. PMID: 24713698; PMCID: PMC4031532.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
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