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Ye Chen-Izu

TitleASSOC PROF-AY-B/E/E
InstitutionUniversity of California Davis
DepartmentMED: PHARMACOLOGY
AddressDavis Campsu
CA 95616
Phone530-752-3232
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhang XD, Coulibaly ZA, Chen WC, Ledford HA, Lee JH, Sirish P, Dai G, Jian Z, Chuang F, Brust-Mascher I, Yamoah EN, Chen-Izu Y, Izu LT, Chiamvimonvat N. Coupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes. Sci Rep. 2018 Mar 16; 8(1):4670. PMID: 29549309.
      View in: PubMed
    2. Hegyi B, Bossuyt J, Griffiths LG, Shimkunas R, Coulibaly Z, Jian Z, Grimsrud KN, Sondergaard CS, Ginsburg KS, Chiamvimonvat N, Belardinelli L, Varró A, Papp JG, Pollesello P, Levijoki J, Izu LT, Boyd WD, Bányász T, Bers DM, Chen-Izu Y. Complex electrophysiological remodeling in postinfarction ischemic heart failure. Proc Natl Acad Sci U S A. 2018 Mar 27; 115(13):E3036-E3044. PMID: 29531045.
      View in: PubMed
    3. Coulibaly Z, Chen-Izu Y, Izu LT. Avoiding phantasms. Cardiovasc Res. 2017 Dec 01; 113(14):1703-1704. PMID: 29036639.
      View in: PubMed
    4. Hegyi B, Horváth B, Váczi K, Gönczi M, Kistamás K, Ruzsnavszky F, Veress R, Izu LT, Chen-Izu Y, Bányász T, Magyar J, Csernoch L, Nánási PP, Szentandrássy N. Ca2+-activated Cl- current is antiarrhythmic by reducing both spatial and temporal heterogeneity of cardiac repolarization. J Mol Cell Cardiol. 2017 Aug; 109:27-37. PMID: 28668303.
      View in: PubMed
    5. Bers DM, Chen-Izu Y. K+ channels and cardiac electrophysiology. J Physiol. 2017 Apr 01; 595(7):2205-2207. PMID: 28370016.
      View in: PubMed
    6. Chen-Izu Y, Izu LT. Mechano-chemo-transduction in cardiac myocytes. J Physiol. 2017 Jun 15; 595(12):3949-3958. PMID: 28098356.
      View in: PubMed
    7. Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger CM, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, Bers DM, Nerbonne JM. Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics. J Physiol. 2017 Apr 01; 595(7):2229-2252. PMID: 27808412.
      View in: PubMed
    8. Grandi E, Sanguinetti MC, Bartos DC, Bers DM, Chen-Izu Y, Chiamvimonvat N, Colecraft HM, Delisle BP, Heijman J, Navedo MF, Noskov S, Proenza C, Vandenberg JI, Yarov-Yarovoy V. Potassium channels in the heart: structure, function and regulation. J Physiol. 2017 Apr 01; 595(7):2209-2228. PMID: 27861921.
      View in: PubMed
    9. Hegyi B, Bányász T, Shannon TR, Chen-Izu Y, Izu LT. Electrophysiological Determination of Submembrane Na(+) Concentration in Cardiac Myocytes. Biophys J. 2016 Sep 20; 111(6):1304-1315. PMID: 27653489.
      View in: PubMed
    10. Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. J Mol Cell Cardiol. 2016 09; 98:62-72. PMID: 27318036.
      View in: PubMed
    11. Hegyi B, Chen-Izu Y, Jian Z, Shimkunas R, Izu LT, Banyasz T. KN-93 inhibits IKr in mammalian cardiomyocytes. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):173-6. PMID: 26463508.
      View in: PubMed
    12. Oda T, Yang Y, Uchinoumi H, Thomas DD, Chen-Izu Y, Kato T, Yamamoto T, Yano M, Cornea RL, Bers DM. Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity. J Mol Cell Cardiol. 2015 Aug; 85:240-8. PMID: 26092277; PMCID: PMC4530019.
    13. Chen-Izu Y, Izu LT. Measuring the metrics: Correlating t-tubule structure and muscle contraction in the intact heart. J Mol Cell Cardiol. 2015 Aug; 85:153-4. PMID: 26031703.
      View in: PubMed
    14. Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, Qu Z, Rajamani S, Rippinger CM, Sejersted OM, O'Rourke B, Weiss JN, Varró A, Zaza A. Deranged sodium to sudden death. J Physiol. 2015 Mar 15; 593(6):1331-45. PMID: 25772289; PMCID: PMC4376414.
    15. Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM. Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol. 2015 Mar 15; 593(6):1347-60. PMID: 25772290.
      View in: PubMed
    16. Yang PC, Song Y, Giles WR, Horvath B, Chen-Izu Y, Belardinelli L, Rajamani S, Clancy CE. A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current. J Physiol. 2015 Mar 15; 593(6):1429-42. PMID: 25545172; PMCID: PMC4376422.
    17. Bers DM, Chen-Izu Y. Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia. J Physiol. 2015 Mar 15; 593(6):1327-9. PMID: 25772288; PMCID: PMC4376413.
    18. Jian Z, Han H, Zhang T, Puglisi J, Izu LT, Shaw JA, Onofiok E, Erickson JR, Chen YJ, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff JC, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu Y. Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Sci Signal. 2014 Mar 18; 7(317):ra27. PMID: 24643800; PMCID: PMC4103414.
    19. Banyasz T, Jian Z, Horvath B, Khabbaz S, Izu LT, Chen-Izu Y. Beta-adrenergic stimulation reverses the I Kr-I Ks dominant pattern during cardiac action potential. Pflugers Arch. 2014 Nov; 466(11):2067-76. PMID: 24535581; PMCID: PMC4138296.
    20. Horvath B, Banyasz T, Jian Z, Hegyi B, Kistamas K, Nanasi PP, Izu LT, Chen-Izu Y. Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations. J Mol Cell Cardiol. 2013 Nov; 64:59-68. PMID: 24012538; PMCID: PMC3856763.
    21. Puglisi JL, Negroni JA, Chen-Izu Y, Bers DM. The force-frequency relationship: insights from mathematical modeling. Adv Physiol Educ. 2013 Mar; 37(1):28-34. PMID: 23471245; PMCID: PMC3776472.
    22. Izu LT, Xie Y, Sato D, Bányász T, Chen-Izu Y. Ca²? waves in the heart. J Mol Cell Cardiol. 2013 May; 58:118-24. PMID: 23220129.
      View in: PubMed
    23. Banyasz T, Horvath B, Jian Z, Izu LT, Chen-Izu Y. Profile of L-type Ca(2+) current and Na(+)/Ca(2+) exchange current during cardiac action potential in ventricular myocytes. Heart Rhythm. 2012 Jan; 9(1):134-42. PMID: 21884673; PMCID: PMC3252888.
    24. Banyasz T, Horvath B, Jian Z, Izu LT, Chen-Izu Y. Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp. J Mol Cell Cardiol. 2011 Mar; 50(3):578-81. PMID: 21215755; PMCID: PMC3047417.
    25. Chen-Izu Y. Multiple levels of the single L-type Ca2+ channel conductance in adult mammalian ventricular myocytes. Biochem Biophys Res Commun. 2010 Jan 01; 391(1):604-8. PMID: 19932083; PMCID: PMC2818605.
    26. Banyasz T, Lozinskiy I, Payne CE, Edelmann S, Norton B, Chen B, Chen-Izu Y, Izu LT, Balke CW. Transformation of adult rat cardiac myocytes in primary culture. Exp Physiol. 2008 Mar; 93(3):370-82. PMID: 18156167.
      View in: PubMed
    27. Chen-Izu Y, Chen L, Bányász T, McCulle SL, Norton B, Scharf SM, Agarwal A, Patwardhan A, Izu LT, Balke CW. Hypertension-induced remodeling of cardiac excitation-contraction coupling in ventricular myocytes occurs prior to hypertrophy development. Am J Physiol Heart Circ Physiol. 2007 Dec; 293(6):H3301-10. PMID: 17873027.
      View in: PubMed
    28. Chen-Izu Y, McCulle SL, Ward CW, Soeller C, Allen BM, Rabang C, Cannell MB, Balke CW, Izu LT. Three-dimensional distribution of ryanodine receptor clusters in cardiac myocytes. Biophys J. 2006 Jul 01; 91(1):1-13. PMID: 16603500; PMCID: PMC1479079.