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Yuanpei Li

Title(s)Associate Professor, Biochemistry and Molecular Medicine
SchoolUniversity of California, Davis
Address2700 Stockton Blvd
CA 95817
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    1. Porphyrin-Based Nanomedicines for Cancer Treatment. Bioconjug Chem. 2019 06 19; 30(6):1585-1603. Xue X, Lindstrom A, Li Y. PMID: 31023011.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    2. Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia. Nanomedicine. 2019 08; 20:102004. Lin TY, Zhu Y, Li Y, Zhang H, Ma AH, Long Q, Keck J, Lam KS, Pan CX, Jonas BA. PMID: 31055076.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy in vivo. Biomed Opt Express. 2019 Jan 01; 10(1):151-166. Goswami M, Wang X, Zhang P, Xiao W, Karlen SJ, Li Y, Zawadzki RJ, Burns ME, Lam KS, Pugh EN. PMID: 30775090.
      View in: PubMed   Mentions:
    4. A facile approach to fabricate self-assembled magnetic nanotheranostics for drug delivery and imaging. Nanoscale. 2018 Nov 29; 10(46):21634-21639. Yuan Y, He Y, Bo R, Ma Z, Wang Z, Dong L, Lin TY, Xue X, Li Y. PMID: 30457141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing. Anal Chem. 2018 12 04; 90(23):13969-13977. Li J, Tan W, Xiao W, Carney RP, Men Y, Li Y, Quon G, Ajena Y, Lam KS, Pan T. PMID: 30358386.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. A polymer-free, biomimicry drug self-delivery system fabricated via a synergistic combination of bottom-up and top-down approaches. J Mater Chem B. 2018 12 21; 6(47):7842-7853. Xu X, Yang G, Xue X, Lu H, Wu H, Huang Y, Jing D, Xiao W, Tian J, Yao W, Pan CX, Lin TY, Li Y. PMID: 31380107.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer. Nano Lett. 2018 11 14; 18(11):7092-7103. Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS. PMID: 30339018.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment. Nat Commun. 2018 09 07; 9(1):3653. Xue X, Huang Y, Bo R, Jia B, Wu H, Yuan Y, Wang Z, Ma Z, Jing D, Xu X, Yu W, Lin TY, Li Y. PMID: 30194413.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. A highly integrated precision nanomedicine strategy to target esophageal squamous cell cancer molecularly and physically. Nanomedicine. 2018 10; 14(7):2103-2114. Wang XS, Ding XZ, Li XC, He Y, Kong DJ, Zhang L, Hu XC, Yang JQ, Zhao MQ, Gao SG, Lin TY, Li Y. PMID: 30047470.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy. Adv Funct Mater. 2018 Aug 15; 28(33). Wang Z, Xue X, He Y, Lu Z, Jia B, Wu H, Yuan Y, Huang Y, Wang H, Lu H, Lam KS, Lin TY, Li Y. PMID: 31303869.
      View in: PubMed   Mentions:
    11. Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo. Nanomedicine (Lond). 2018 05; 13(10):1107-1120. Wang XS, Zhang L, Li X, Kong DJ, Hu XC, Ding XZ, Yang JQ, Zhao MQ, He Y, Lam KS, Gao SG, Lin TY, Li Y. PMID: 29874151.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Reversibly disulfide cross-linked micelles improve the pharmacokinetics and facilitate the targeted, on-demand delivery of doxorubicin in the treatment of B-cell lymphoma. Nanoscale. 2018 May 03; 10(17):8207-8216. Xiao K, Liu Q, Al Awwad N, Zhang H, Lai L, Luo Y, Lee JS, Li Y, Lam KS. PMID: 29682647.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy. Biomaterials. 2018 04; 161:203-215. Xue X, Huang Y, Wang X, Wang Z, Carney RP, Li X, Yuan Y, He Y, Lin TY, Li Y. PMID: 29421556.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    14. Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model. Nanomedicine. 2018 04; 14(3):789-799. Long Q, Lin TY, Huang Y, Li X, Ma AH, Zhang H, Carney R, Airhart S, Lam KS, deVere White RW, Pan CX, Li Y. PMID: 29317342.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    15. "One-Pot" Fabrication of Highly Versatile and Biocompatible Poly(vinyl alcohol)-porphyrin-based Nanotheranostics. Theranostics. 2017; 7(16):3901-3914. Luo Y, Wu H, Feng C, Xiao K, Yang X, Liu Q, Lin TY, Zhang H, Walton JH, Ajena Y, Hu Y, Lam KS, Li Y. PMID: 29109786.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    16. Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma. Mol Cancer Ther. 2017 11; 16(11):2627-2638. Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y. PMID: 28847988.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer. J Control Release. 2017 Oct 28; 264:169-179. Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y. PMID: 28847739.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    18. Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development. J Biol Chem. 2017 09 08; 292(36):15121-15132. He W, Felderman M, Evans AC, Geng J, Homan D, Bourguet F, Fischer NO, Li Y, Lam KS, Noy A, Xing L, Cheng RH, Rasley A, Blanchette CD, Kamrud K, Wang N, Gouvis H, Peterson TC, Hubby B, Coleman MA. PMID: 28739800.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. J Control Release. 2017 09 10; 261:297-306. Yang X, Xue X, Luo Y, Lin TY, Zhang H, Lac D, Xiao K, He Y, Jia B, Lam KS, Li Y. PMID: 28700898.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. A facile strategy for fine-tuning the stability and drug release of stimuli-responsive cross-linked micellar nanoparticles towards precision drug delivery. Nanoscale. 2017 Jun 14; 9(23):7765-7770. Xiao K, Lin TY, Lam KS, Li Y. PMID: 28585953.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer. Acta Pharmacol Sin. 2017 Jun; 38(6):931-942. Wang XS, Kong DJ, Lin TY, Li XC, Izumiya Y, Ding XZ, Zhang L, Hu XC, Yang JQ, Gao SG, Lam KS, Li YP. PMID: 28552907.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Cholic acid-based novel micellar nanoplatform for delivering FDA-approved taxanes. Nanomedicine (Lond). 2017 May; 12(10):1153-1164. Bharadwaj G, Nhan V, Yang S, Li X, Narayanan A, Macarenco AC, Shi Y, Yang D, Vieira LS, Xiao W, Li Y, Lam KS. PMID: 28447909.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    23. Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 04 21; 12(4):1075-1086. Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. PMID: 28195700.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    24. Active targeting theranostic iron oxide nanoparticles for MRI and magnetic resonance-guided focused ultrasound ablation of lung cancer. Biomaterials. 2017 05; 127:25-35. Wang Z, Qiao R, Tang N, Lu Z, Wang H, Zhang Z, Xue X, Huang Z, Zhang S, Zhang G, Li Y. PMID: 28279919.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles. J Vis Exp. 2016 12 23; (118). Li Y, Bharadwaj G, Lee JS. PMID: 28060268.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    26. Disulfide-crosslinked nanomicelles confer cancer-specific drug delivery and improve efficacy of paclitaxel in bladder cancer. Nanotechnology. 2016 Oct 21; 27(42):425103. Pan A, Zhang H, Li Y, Lin TY, Wang F, Lee J, Cheng M, Dall'Era M, Li T, deVere White R, Pan CX, Lam KS. PMID: 27640312.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    27. Developing a Nanoparticle-Delivered High-Efficacy Treatment for Infantile Hemangiomas Using a Mouse Hemangioendothelioma Model. Plast Reconstr Surg. 2016 Aug; 138(2):410-7. Orbay H, Li Y, Xiao W, Cherry SR, Lam K, Sahar DE. PMID: 27465164.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer. Biomaterials. 2016 10; 104:339-51. Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX. PMID: 27479049.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    29. HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy. Theranostics. 2016; 6(9):1324-35. Lin TY, Guo W, Long Q, Ma A, Liu Q, Zhang H, Huang Y, Chandrasekaran S, Pan C, Lam KS, Li Y. PMID: 27375782.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    30. Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer. Biomaterials. 2015 Oct; 67:183-93. Xiao K, Li YP, Wang C, Ahmad S, Vu M, Kuma K, Cheng YQ, Lam KS. PMID: 26218744.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    31. Nanomedicine in veterinary oncology. Vet J. 2015 Aug; 205(2):189-97. Lin TY, Rodriguez CO, Li Y. PMID: 25862394.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    32. In vivo wide-field multispectral scanning laser ophthalmoscopy-optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia, and Müller glia, and mapping of the mouse retinal and choroidal vasculature. J Biomed Opt. 2015; 20(12):126005. Zhang P, Zam A, Jian Y, Wang X, Li Y, Lam KS, Burns ME, Sarunic MV, Pugh EN, Zawadzki RJ. PMID: 26677070.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    33. A smart and versatile theranostic nanomedicine platform based on nanoporphyrin. Nat Commun. 2014 Aug 26; 5:4712. Li Y, Lin TY, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, Lam KS. PMID: 25158161.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    34. Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Sci Signal. 2014 Mar 18; 7(317):ra27. Jian Z, Han H, Zhang T, Puglisi J, Izu LT, Shaw JA, Onofiok E, Erickson JR, Chen YJ, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff JC, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu Y. PMID: 24643800.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    35. Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014; 9(12):1807-20. Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, Pan CX. PMID: 24628688.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Telodendrimer-based nanocarriers for the treatment of ovarian cancer. Ther Deliv. 2013 Oct; 4(10):1279-92. Xiao K, Suby N, Li Y, Lam KS. PMID: 24116912.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. Stimuli-responsive cross-linked micelles for on-demand drug delivery against cancers. Adv Drug Deliv Rev. 2014 Feb; 66:58-73. Li Y, Xiao K, Zhu W, Deng W, Lam KS. PMID: 24060922.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    38. CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. PLoS One. 2013; 8(8):e70910. Guo W, Liu R, Bhardwaj G, Ma AH, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, Lam KS, Kung HJ. PMID: 23967135.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    39. Immobilized OBOC combinatorial bead array to facilitate multiplicative screening. Comb Chem High Throughput Screen. 2013 Jul; 16(6):441-448. Xiao W, Bononi FC, Townsend J, Li Y, Liu R, Lam KS. PMID: 23488896.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    40. Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer. Nanomedicine (Lond). 2013 Aug; 8(8):1239-51. Lin TY, Li YP, Zhang H, Luo J, Goodwin N, Gao T, White Rde V, Lam KS, Pan CX. PMID: 23199207.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    41. Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins. ACS Nano. 2012 Nov 27; 6(11):9485-95. Li Y, Budamagunta MS, Luo J, Xiao W, Voss JC, Lam KS. PMID: 23106540.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    42. Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. Int J Nanomedicine. 2012; 7:2793-804. Lin TY, Zhang H, Luo J, Li Y, Gao T, Lara PN, de Vere White R, Lam KS, Pan CX. PMID: 22745542.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    43. Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell lymphoma. Mol Pharm. 2012 Jun 04; 9(6):1727-35. Kato J, Li Y, Xiao K, Lee JS, Luo J, Tuscano JM, O'Donnell RT, Lam KS. PMID: 22530955.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    44. "OA02" peptide facilitates the precise targeting of paclitaxel-loaded micellar nanoparticles to ovarian cancer in vivo. Cancer Res. 2012 Apr 15; 72(8):2100-10. Xiao K, Li Y, Lee JS, Gonik AM, Dong T, Fung G, Sanchez E, Xing L, Cheng HR, Luo J, Lam KS. PMID: 22396491.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    45. Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols. Angew Chem Int Ed Engl. 2012 Mar 19; 51(12):2864-9. Li Y, Xiao W, Xiao K, Berti L, Luo J, Tseng HP, Fung G, Lam KS. PMID: 22253091.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    46. Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells. Nanomedicine. 2012 Oct; 8(7):1116-24. Zhang H, Luo J, Li Y, Henderson PT, Wang Y, Wachsmann-Hogiu S, Zhao W, Lam KS, Pan CX. PMID: 22197725.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell lymphoma. J Control Release. 2011 Oct 30; 155(2):272-81. Xiao K, Luo J, Li Y, Lee JS, Fung G, Lam KS. PMID: 21787818.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    48. Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery. Biomaterials. 2011 Sep; 32(27):6633-45. Li Y, Xiao K, Luo J, Xiao W, Lee JS, Gonik AM, Kato J, Dong TA, Lam KS. PMID: 21658763.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    49. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials. 2011 May; 32(13):3435-46. Xiao K, Li Y, Luo J, Lee JS, Xiao W, Gonik AM, Agarwal RG, Lam KS. PMID: 21295849.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    50. Maximization of loading and stability of ssDNA:iron oxide nanoparticle complexes formed through electrostatic interaction. Langmuir. 2010 Dec 07; 26(23):18293-9. Berti L, Woldeyesus T, Li Y, Lam KS. PMID: 21047109.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    51. Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for cancer treatment. Bioconjug Chem. 2010 Jul 21; 21(7):1216-24. Luo J, Xiao K, Li Y, Lee JS, Shi L, Tan YH, Xing L, Holland Cheng R, Liu GY, Lam KS. PMID: 20536174.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    52. The Passive Targeting of Polymeric Micelles in Various Types and Sizes of Tumor Models. Nanoscience and Nanotechnology Letters. 2010 Jun 1; 2(2):79-85. Kai Xiao, Juntao Luo, Yuanpei Li, Wenwu Xiao, Joyce S. Lee, Abby M. Gonik, Kit S. Lam. .
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    53. From combinatorial chemistry to cancer targeting nanotherapeutics. Proceedings of SPIE. 2010 Apr 23; 7679:767909-767909-8. Kai Xiao, Juntao Luo, Yuanpei Li, Wenwu Xiao, Joyce S. Lee, Abby M. Gonik, Kit S. Lam. .
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    54. A novel size-tunable nanocarrier system for targeted anticancer drug delivery. J Control Release. 2010 Jun 15; 144(3):314-23. Li Y, Xiao K, Luo J, Lee J, Pan S, Lam KS. PMID: 20211210.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    55. Paclitaxel-loaded micelles composed of folate-poly(ethylene glycol) and poly(?-benzyl l-glutamate) diblock copolymer. Colloids and Surfaces A Physicochemical and Engineering Aspects. 2010 Jan 1; 353(2-3):140-148. Zhuo Du, Shirong Pan, Qiao Yu, Yuanpei Li, Yuting Wen, Wei Zhang, Min Feng, Chuanbin Wu. .
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    56. A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer. Biomaterials. 2009 Oct; 30(30):6006-16. Xiao K, Luo J, Fowler WL, Li Y, Lee JS, Xing L, Cheng RH, Wang L, Lam KS. PMID: 19660809.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    57. Novel thermo-sensitive core-shell nanoparticles for targeted paclitaxel delivery. Nanotechnology. 2009 Feb 11; 20(6):065104. Li Y, Pan S, Zhang W, Du Z. PMID: 19417372.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    58. Novel thermo-sensitive membranes prepared by rapid bulk photo-grafting polymerization of N,N-diethylacrylamide onto the microfiltration membranes Nylon. Journal of Membrane Science. 2006 Oct 1; 283(1-2):13-20. Guangguo Wu, Yuanpei Li, Mei Han, Xiaoxuan Liu. .
      View in: Publisher Site   Mentions:
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