Clifford G Tepper

Title(s)Researcher, Biochemistry and Molecular Medicine
SchoolSchool of Medicine
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    1. Pharmacogenetic Gene-Drug Associations in Pediatric Burn and Surgery Patients. J Burn Care Res. 2022 Sep 01; 43(5):987-996. Grimsrud KN, Davis RR, Tepper CG, Palmieri TL. PMID: 35639664; PMCID: PMC9435482.
      View in: PubMed   Mentions:    Fields:    
    2. KSHV Topologically Associating Domains in Latent and Reactivated Viral Chromatin. J Virol. 2022 07 27; 96(14):e0056522. Campbell M, Chantarasrivong C, Yanagihashi Y, Inagaki T, Davis RR, Nakano K, Kumar A, Tepper CG, Izumiya Y. PMID: 35867573; PMCID: PMC9327698.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4. Cell Rep. 2022 05 10; 39(6):110788. Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, Wang KH, Inagaki T, Chuang F, Davis RR, Tepper CG, Nakano K, Izumiya C, Shimoda M, Nakajima KI, Merleev A, Zheng ZM, Campbell M, Izumiya Y. PMID: 35545047; PMCID: PMC9153692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Use of RNA-Seq and a Transgenic Mouse Model to Identify Genes Which May Contribute to Mutant p53-Driven Prostate Cancer Initiation. Biology (Basel). 2022 Jan 29; 11(2). Vinall R, Chen Q, Talbott G, Ramsamooj R, Dang A, Tepper CG, Borowsky A. PMID: 35205085; PMCID: PMC8869245.
      View in: PubMed   Mentions:
    5. KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth. Commun Biol. 2021 12 02; 4(1):1330. Shimoda M, Lyu Y, Wang KH, Kumar A, Miura H, Meckler JF, Davis RR, Chantarasrivong C, Izumiya C, Tepper CG, Nakajima KI, Tuscano J, Barisone G, Izumiya Y. PMID: 34857874; PMCID: PMC8639922.
      View in: PubMed   Mentions: 1  Translation:HumansCells
    6. ARVib suppresses growth of advanced prostate cancer via inhibition of androgen receptor signaling. Oncogene. 2021 09; 40(35):5379-5392. Liu C, Armstrong CM, Ning S, Yang JC, Lou W, Lombard AP, Zhao J, Wu CY, Yu A, Evans CP, Tepper CG, Li PK, Gao AC. PMID: 34272475; PMCID: PMC8413131.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    7. Novel Patient Metastatic Pleural Effusion-Derived Xenograft Model of Renal Medullary Carcinoma Demonstrates Therapeutic Efficacy of Sunitinib. Front Oncol. 2021; 11:648097. Lee AQ, Ijiri M, Rodriguez R, Gandour-Edwards R, Lee J, Tepper CG, Li Y, Beckett L, Lam K, Goodwin N, Satake N. PMID: 33842362; PMCID: PMC8032976.
      View in: PubMed   Mentions: 1  
    8. Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer. Sci Rep. 2021 01 13; 11(1):927. Fite BZ, Wang J, Kare AJ, Ilovitsh A, Chavez M, Ilovitsh T, Zhang N, Chen W, Robinson E, Zhang H, Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Davis RR, Tepper CG, Borowsky AD, Ferrara KW. PMID: 33441763; PMCID: PMC7806949.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    9. Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma. Gynecol Oncol. 2020 06; 157(3):783-792. Chen H, Gotimer K, De Souza C, Tepper CG, Karnezis AN, Leiserowitz GS, Chien J, Smith LH. PMID: 32253045; PMCID: PMC7819712.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    10. Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis. Acta Neuropathol Commun. 2019 04 10; 7(1):55. Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen F. PMID: 30971321; PMCID: PMC6456988.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    11. Obatoclax, a BH3 Mimetic, Enhances Cisplatin-Induced Apoptosis and Decreases the Clonogenicity of Muscle Invasive Bladder Cancer Cells via Mechanisms That Involve the Inhibition of Pro-Survival Molecules as Well as Cell Cycle Regulators. Int J Mol Sci. 2019 Mar 14; 20(6). Steele TM, Talbott GC, Sam A, Tepper CG, Ghosh PM, Vinall RL. PMID: 30875757; PMCID: PMC6470498.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    12. A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials. J Mammary Gland Biol Neoplasia. 2019 06; 24(2):149-162. Pénzváltó Z, Chen JQ, Tepper CG, Davis RR, Silvestrini MT, Umeh-Garcia M, Sweeney C, Borowsky AD. PMID: 30810966; PMCID: PMC6612594.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    13. Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer. Nat Commun. 2018 11 16; 9(1):4700. Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel ODV, Tepper CG, Chen HW, Dall'Era M, Evans CP, Gao AC. PMID: 30446660; PMCID: PMC6240084.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    14. KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene. 2019 01; 38(1):17-32. Wang HJ, Pochampalli M, Wang LY, Zou JX, Li PS, Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, Ann DK, Gao AC, Evans CP, Izumiya Y, Chuu CP, Wang WC, Chen HW, Kung HJ. PMID: 30072740; PMCID: PMC6755995.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    15. Identification of integrin drug targets for 17 solid tumor types. Oncotarget. 2018 Jul 10; 9(53):30146-30162. Arun AS, Tepper CG, Lam KS. PMID: 30046394; PMCID: PMC6059022.
      View in: PubMed   Mentions: 7     Fields:    
    16. Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. Theranostics. 2018; 8(13):3611-3628. Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW. PMID: 30026870; PMCID: PMC6037035.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    17. High frequency of the PNPLA3 rs738409 [G] single-nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease. Cancer. 2018 04 01; 124 Suppl 7:1583-1589. Tepper CG, Dang JHT, Stewart SL, Fang DM, Wong KA, Liu SY, Davis RR, Dao DY, Gregg JP, Török NJ, Chen MS. PMID: 29578593; PMCID: PMC5875707.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation. Nat Commun. 2018 01 04; 9(1):49. Campbell M, Watanabe T, Nakano K, Davis RR, Lyu Y, Tepper CG, Durbin-Johnson B, Fujimuro M, Izumiya Y. PMID: 29302027; PMCID: PMC5754359.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    19. ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation. J Virol. 2017 Nov 01; 91(21). Lyu Y, Nakano K, Davis RR, Tepper CG, Campbell M, Izumiya Y. PMID: 28835494; PMCID: PMC5640855.
      View in: PubMed   Mentions: 9     Fields:    
    20. Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma. Mol Cancer Ther. 2017 11; 16(11):2627-2638. Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y. PMID: 28847988; PMCID: PMC5914504.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    21. The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer. Clin Cancer Res. 2017 Nov 01; 23(21):6580-6591. Zeng SX, Zhu Y, Ma AH, Yu W, Zhang H, Lin TY, Shi W, Tepper CG, Henderson PT, Airhart S, Guo JM, Xu CL, deVere White RW, Pan CX. PMID: 28808038; PMCID: PMC5668181.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    22. The androgen receptor is a negative regulator of eIF4E phosphorylation at S209: implications for the use of mTOR inhibitors in advanced prostate cancer. Oncogene. 2017 11 16; 36(46):6359-6373. D'Abronzo LS, Bose S, Crapuchettes ME, Beggs RE, Vinall RL, Tepper CG, Siddiqui S, Mudryj M, Melgoza FU, Durbin-Johnson BP, deVere White RW, Ghosh PM. PMID: 28745319; PMCID: PMC5690844.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    23. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017 03 20; 8(1):69. Clark KC, Fierro FA, Ko EM, Walker NJ, Arzi B, Tepper CG, Dahlenburg H, Cicchetto A, Kol A, Marsh L, Murphy WJ, Fazel N, Borjesson DL. PMID: 28320483; PMCID: PMC5360077.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    24. Microdose-Induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice. Mol Cancer Ther. 2017 02; 16(2):376-387. Zimmermann M, Wang SS, Zhang H, Lin TY, Malfatti M, Haack K, Ognibene T, Yang H, Airhart S, Turteltaub KW, Cimino GD, Tepper CG, Drakaki A, Chamie K, de Vere White R, Pan CX, Henderson PT. PMID: 27903751; PMCID: PMC5335870.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    25. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes. Cancer Lett. 2016 08 10; 378(2):69-79. Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. PMID: 27164560; PMCID: PMC7505026.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    26. Decreased expression of let-7c is associated with non-response of muscle-invasive bladder cancer patients to neoadjuvant chemotherapy. Genes Cancer. 2016 Mar; 7(3-4):86-97. Vinall RL, Tepper CG, Ripoll AA, Gandour-Edwards RF, Durbin-Johnson BP, Yap SA, Ghosh PM, deVere White RW. PMID: 27382433; PMCID: PMC4918947.
      View in: PubMed   Mentions: 9  
    27. miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src. Cancer Res. 2015 Dec 15; 75(24):5309-17. Shi XB, Ma AH, Xue L, Li M, Nguyen HG, Yang JC, Tepper CG, Gandour-Edwards R, Evans CP, Kung HJ, deVere White RW. PMID: 26573802; PMCID: PMC4681619.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    28. Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy. PLoS One. 2015; 10(8):e0134346. Pan CX, Zhang H, Tepper CG, Lin TY, Davis RR, Keck J, Ghosh PM, Gill P, Airhart S, Bult C, Gandara DR, Liu E, de Vere White RW. PMID: 26270481; PMCID: PMC4535951.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    29. Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent. PLoS One. 2015; 10(6):e0129895. Chen JQ, Mori H, Cardiff RD, Trott JF, Hovey RC, Hubbard NE, Engelberg JA, Tepper CG, Willis BJ, Khan IH, Ravindran RK, Chan SR, Schreiber RD, Borowsky AD. PMID: 26075897; PMCID: PMC4468083.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. Evaluation of commercially available RNA amplification kits for RNA sequencing using very low input amounts of total RNA. J Biomol Tech. 2015 Apr; 26(1):4-18. Shanker S, Paulson A, Edenberg HJ, Peak A, Perera A, Alekseyev YO, Beckloff N, Bivens NJ, Donnelly R, Gillaspy AF, Grove D, Gu W, Jafari N, Kerley-Hamilton JS, Lyons RH, Tepper C, Nicolet CM. PMID: 25649271; PMCID: PMC4310221.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    31. Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. PLoS Pathog. 2013; 9(12):e1003813. Toth Z, Brulois K, Lee HR, Izumiya Y, Tepper C, Kung HJ, Jung JU. PMID: 24367262; PMCID: PMC3868514.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    32. The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi's sarcoma associated herpesvirus reactivation. BMC Genomics. 2013 Nov 23; 14:824. Chang PC, Cheng CY, Campbell M, Yang YC, Hsu HW, Chang TY, Chu CH, Lee YW, Hung CL, Lai SM, Tepper CG, Hsieh WP, Wang HW, Tang CY, Wang WC, Kung HJ. PMID: 24267727; PMCID: PMC4046822.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    33. On the origins of the androgen receptor low molecular weight species. Horm Cancer. 2013 Oct; 4(5):259-69. Mudryj M, Tepper CG. PMID: 23860689; PMCID: PMC4353596.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Modeling truncated AR expression in a natural androgen responsive environment and identification of RHOB as a direct transcriptional target. PLoS One. 2012; 7(11):e49887. Tsai HC, Boucher DL, Martinez A, Tepper CG, Kung HJ. PMID: 23209612; PMCID: PMC3510170.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    35. Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization. Endocr Relat Cancer. 2012 Dec; 19(6):759-77. Mooso BA, Vinall RL, Tepper CG, Savoy RM, Cheung JP, Singh S, Siddiqui S, Wang Y, Bedolla RG, Martinez A, Mudryj M, Kung HJ, Devere White RW, Ghosh PM. PMID: 22993077; PMCID: PMC3540117.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    36. Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells. Oncogene. 2013 Aug 29; 32(35):4130-8. Shi XB, Xue L, Ma AH, Tepper CG, Gandour-Edwards R, Kung HJ, deVere White RW. PMID: 23069658; PMCID: PMC4111479.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    37. Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Mol Cell Biol. 2012 Aug; 32(15):3121-31. Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X, Kung HJ, Gao AC, Zou JX, Chen HW. PMID: 22645312; PMCID: PMC3434505.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    38. Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen. J Biol Chem. 2012 Feb 17; 287(8):5806-18. Campbell M, Chang PC, Huerta S, Izumiya C, Davis R, Tepper CG, Kim KY, Shevchenko B, Wang DH, Jung JU, Luciw PA, Kung HJ, Izumiya Y. PMID: 22179613; PMCID: PMC3285351.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    39. Dual blockade of PKA and NF-κB inhibits H2 relaxin-mediated castrate-resistant growth of prostate cancer sublines and induces apoptosis. Horm Cancer. 2011 Aug; 2(4):224-38. Vinall RL, Mahaffey CM, Davis RR, Luo Z, Gandour-Edwards R, Ghosh PM, Tepper CG, de Vere White RW. PMID: 21789713; PMCID: PMC3249648.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    40. Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy. Cancer Chemother Pharmacol. 2012 Jan; 69(1):185-94. Holland WS, Tepper CG, Pietri JE, Chinn DC, Gandara DR, Mack PC, Lara PN. PMID: 21644050; PMCID: PMC4562405.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    41. Recombinant origin of the retrovirus XMRV. Science. 2011 Jul 01; 333(6038):97-101. Paprotka T, Delviks-Frankenberry KA, Cingöz O, Martinez A, Kung HJ, Tepper CG, Hu WS, Fivash MJ, Coffin JM, Pathak VK. PMID: 21628392; PMCID: PMC3278917.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansAnimalsCells
    42. Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor. J Virol. 2011 Apr; 85(7):3283-93. Chang PC, Fitzgerald LD, Hsia DA, Izumiya Y, Wu CY, Hsieh WP, Lin SF, Campbell M, Lam KS, Luciw PA, Tepper CG, Kung HJ. PMID: 21228229; PMCID: PMC3067885.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    43. Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines. Endocr Relat Cancer. 2010 Dec; 17(4):857-73. Chen H, Libertini SJ, George M, Dandekar S, Tepper CG, Al-Bataina B, Kung HJ, Ghosh PM, Mudryj M. PMID: 20634343; PMCID: PMC3539310.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    44. miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes. Prostate. 2011 Apr; 71(5):538-49. Shi XB, Xue L, Ma AH, Tepper CG, Kung HJ, White RW. PMID: 20886540; PMCID: PMC3017658.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    45. ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2. Cancer Res. 2010 Nov 15; 70(22):9402-12. Kalashnikova EV, Revenko AS, Gemo AT, Andrews NP, Tepper CG, Zou JX, Cardiff RD, Borowsky AD, Chen HW. PMID: 20864510; PMCID: PMC2982862.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    46. Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells. Cancer Res. 2010 Jul 15; 70(14):5994-6003. Chen L, Siddiqui S, Bose S, Mooso B, Asuncion A, Bedolla RG, Vinall R, Tepper CG, Gandour-Edwards R, Shi X, Lu XH, Siddiqui J, Chinnaiyan AM, Mehra R, Devere White RW, Carraway KL, Ghosh PM. PMID: 20587519; PMCID: PMC2905475.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    47. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9671-6. Hsia DA, Tepper CG, Pochampalli MR, Hsia EY, Izumiya C, Huerta SB, Wright ME, Chen HW, Kung HJ, Izumiya Y. PMID: 20457893; PMCID: PMC2906833.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    48. Microarray analysis reveals potential target genes of NF-kappaB2/p52 in LNCaP prostate cancer cells. Prostate. 2010 Feb 15; 70(3):276-87. Nadiminty N, Dutt S, Tepper C, Gao AC. PMID: 19827050.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    49. MicroRNAs and their potential for translation in prostate cancer. Urol Oncol. 2009 May-Jun; 27(3):307-11. DeVere White RW, Vinall RL, Tepper CG, Shi XB. PMID: 19414119; PMCID: PMC2761743.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    50. The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells. J Thorac Oncol. 2009 Apr; 4(4):448-54. Purnell PR, Mack PC, Tepper CG, Evans CP, Green TP, Gumerlock PH, Lara PN, Gandara DR, Kung HJ, Gautschi O. PMID: 19240653; PMCID: PMC2716757.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    51. Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Res. 2009 Apr 15; 69(8):3339-46. Zou JX, Guo L, Revenko AS, Tepper CG, Gemo AT, Kung HJ, Chen HW. PMID: 19318566.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    52. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009 Mar 15; 69(6):2305-13. Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. PMID: 19244107; PMCID: PMC2672822.
      View in: PubMed   Mentions: 437     Fields:    Translation:HumansAnimalsCells
    53. MicroRNAs and prostate cancer. J Cell Mol Med. 2008 Sep-Oct; 12(5A):1456-65. Shi XB, Tepper CG, White RW. PMID: 18624768; PMCID: PMC3918061.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    54. Genistein combined polysaccharide enhances activity of docetaxel, bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines. BJU Int. 2008 Nov; 102(10):1458-66. Burich RA, Holland WS, Vinall RL, Tepper C, White RW, Mack PC. PMID: 18565171.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    55. Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. Cancer Res. 2008 Apr 01; 68(7):2250-8. Gautschi O, Tepper CG, Purnell PR, Izumiya Y, Evans CP, Green TP, Desprez PY, Lara PN, Gandara DR, Mack PC, Kung HJ. PMID: 18381431.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    56. Cancerous miRNAs and their regulation. Cell Cycle. 2008 Jun 01; 7(11):1529-38. Shi XB, Tepper CG, deVere White RW. PMID: 18469525.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    57. An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19983-8. Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, Tepper CG, Evans CP, Kung HJ, deVere White RW. PMID: 18056640; PMCID: PMC2148409.
      View in: PubMed   Mentions: 224     Fields:    Translation:HumansCells
    58. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res. 2007 Oct 01; 67(19):9001-5. Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. PMID: 17909000.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    59. Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway. Oncogene. 2008 Jan 17; 27(4):499-505. Liu S, Vinall RL, Tepper C, Shi XB, Xue LR, Ma AH, Wang LY, Fitzgerald LD, Wu Z, Gandour-Edwards R, deVere White RW, Kung HJ. PMID: 17653089.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    60. The oncogenic potential of a prostate cancer-derived androgen receptor mutant. Prostate. 2007 May 01; 67(6):591-602. Shi XB, Xue L, Tepper CG, Gandour-Edwards R, Ghosh P, Kung HJ, DeVere White RW. PMID: 17262801.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    61. GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms. Prostate. 2007 Apr 01; 67(5):521-35. Tepper CG, Vinall RL, Wee CB, Xue L, Shi XB, Burich R, Mack PC, de Vere White RW. PMID: 17252539.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    62. Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Res. 2006 Nov 01; 66(21):10449-59. Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ. PMID: 17079466.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    63. ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes. Prostate. 2006 Oct 01; 66(14):1474-86. Zou JX, Zhong Z, Shi XB, Tepper CG, deVere White RW, Kung HJ, Chen H. PMID: 16921507.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    64. Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Cancer Res. 2006 Sep 01; 66(17):8439-47. Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ. PMID: 16951154.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    65. Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ. Clin Cancer Res. 2006 Apr 15; 12(8):2613-21. Namba R, Young LJ, Abbey CK, Kim L, Damonte P, Borowsky AD, Qi J, Tepper CG, MacLeod CL, Cardiff RD, Gregg JP. PMID: 16638874.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    66. The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7. Oncogene. 2006 Mar 30; 25(14):2082-93. Vinall RL, Tepper CG, Shi XB, Xue LA, Gandour-Edwards R, de Vere White RW. PMID: 16434975.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    67. Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes. Hum Mol Genet. 2006 Mar 15; 15(6):853-69. Baron CA, Tepper CG, Liu SY, Davis RR, Wang NJ, Schanen NC, Gregg JP. PMID: 16446308.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    68. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis. Prostate. 2006 Jan 01; 66(1):70-81. Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M. PMID: 16114066.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    69. Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer. Cancer Res. 2006 Jan 01; 66(1):175-83. You Z, Shi XB, DuRaine G, Haudenschild D, Tepper CG, Lo SH, Gandour-Edwards R, de Vere White RW, Reddi AH. PMID: 16397230.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    70. An efficient strategy to identify early TPA-responsive genes during differentiation of HL-60 cells. Gene Expr. 2006; 13(3):179-89. Hu LY, Tepper CG, Lo SH, Lin WC. PMID: 17193924; PMCID: PMC6032445.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    71. Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells. Prostate. 2005 Dec 01; 65(4):375-89. Tepper CG, Gregg JP, Shi XB, Vinall RL, Baron CA, Ryan PE, Desprez PY, Kung HJ, deVere White RW. PMID: 16037992.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    72. Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior. Clin Exp Metastasis. 2005; 22(1):47-59. Borowsky AD, Namba R, Young LJ, Hunter KW, Hodgson JG, Tepper CG, McGoldrick ET, Muller WJ, Cardiff RD, Gregg JP. PMID: 16132578.
      View in: PubMed   Mentions: 122     Fields:    Translation:AnimalsCells
    73. Molecular alterations associated with LNCaP cell progression to androgen independence. Prostate. 2004 Aug 01; 60(3):257-71. Shi XB, Ma AH, Tepper CG, Xia L, Gregg JP, Gandour-Edwards R, Mack PC, Kung HJ, deVere White RW. PMID: 15176055.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    74. Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin. Breast Cancer Res. 2004; 6(3):R157-69. Jessen KA, Liu SY, Tepper CG, Karrim J, McGoldrick ET, Rosner A, Munn RJ, Young LJ, Borowsky AD, Cardiff RD, Gregg JP. PMID: 15084239; PMCID: PMC400667.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    75. Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res. 2002 Nov 15; 62(22):6606-14. Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, Pretlow TG, Kung HJ. PMID: 12438256.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    76. Fas-mediated apoptosis of proliferating, transiently growth-arrested, and senescent normal human fibroblasts. Exp Cell Res. 2000 Oct 10; 260(1):9-19. Tepper CG, Seldin MF, Mudryj M. PMID: 11010806.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    77. Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma. Blood. 1999 Sep 01; 94(5):1727-37. Tepper CG, Seldin MF. PMID: 10477698.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    78. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem. 1996 Mar 01; 271(9):4961-5. Chinnaiyan AM, Tepper CG, Seldin MF, O'Rourke K, Kischkel FC, Hellbardt S, Krammer PH, Peter ME, Dixit VM. PMID: 8617770.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    79. Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A. 1995 Aug 29; 92(18):8443-7. Tepper CG, Jayadev S, Liu B, Bielawska A, Wolff R, Yonehara S, Hannun YA, Seldin MF. PMID: 7545303; PMCID: PMC41173.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    80. 1,25-Dihydroxyvitamin D3 protects HL60 cells against apoptosis but down-regulates the expression of the bcl-2 gene. Exp Cell Res. 1993 Dec; 209(2):367-74. Xu HM, Tepper CG, Jones JB, Fernandez CE, Studzinski GP. PMID: 8262155.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    81. Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death. J Cell Biochem. 1993 Jul; 52(3):352-61. Tepper CG, Studzinski GP. PMID: 8366146.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    82. Teniposide induces nuclear but not mitochondrial DNA degradation. Cancer Res. 1992 Jun 15; 52(12):3384-90. Tepper CG, Studzinski GP. PMID: 1596897.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    83. Mitochondrial nucleic acids as internal standards for blot hybridization analyses. Anal Biochem. 1992 May 15; 203(1):127-33. Tepper CG, Pater MM, Pater A, Xu HM, Studzinski GP. PMID: 1524208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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