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Yu-Jui Yvonne Wan, PhD

Title(s)Professor, Pathology And Laboratory Medicine
SchoolUniversity of California, Davis
Phone916-734-4293
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    Collapse Research 
    Collapse Research Activities and Funding
    Liver Cancer Therapy by MiR-22 and Its Inducers
    NIH/NCI R01CA222490Feb 1, 2018 - Jan 31, 2023
    Role: Principal Investigator
    The Role of Probiotic Bifidobacteria and Bile Acid Metabolism in Carcinogenesis
    NIH/NCI U01CA179582Sep 12, 2014 - Aug 31, 2019
    Role: Principal Investigator
    Retinoic Acid, Its Receptors, and the Liver
    NIH/NIDDK R01DK092100Jul 6, 2011 - Apr 30, 2015
    Role: Principal Investigator
    SAMe, RXRalpha-mediated Pathways and ALD
    NIH/NIAAA R01AA014147Sep 30, 2002 - Jul 31, 2008
    Role: Principal Investigator
    Alcohol Pharmacogenetics in Mexican Americans
    NIH/NIAAA R01AA012081Sep 21, 2000 - May 31, 2010
    Role: Principal Investigator
    Retinoids, Nuclear Receptors, and Hepatocyte Proliferation
    NIH/NCI R01CA053596Aug 15, 1991 - Jan 31, 2016
    Role: Principal Investigator
    RETINOIC ACID RECEPTOR ALPHA-FETOPROTEIN AND HEPATOMA
    NIH/NCI R29CA053596Aug 15, 1991 - Jun 1, 1996
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yu S, Wu X, Shi Z, Huynh M, Jena PK, Sheng L, Zhou Y, Han D, Wan YY, Hwang ST. Diet-induced obesity exacerbates imiquimod-mediated psoriasiform dermatitis in anti-PD-1 antibody-treated mice: Implications for patients being treated with checkpoint inhibitors for cancer. J Dermatol Sci. 2020 Jan 24. PMID: 32044178.
      View in: PubMed
    2. Jena PK, Sheng L, Mcneil K, Chau TQ, Yu S, Kiuru M, Fung MA, Hwang ST, Wan YY. Long-term Western diet intake leads to dysregulated bile acid signaling and dermatitis with Th2 and Th17 pathway features in mice. J Dermatol Sci. 2019 Jul; 95(1):13-20. PMID: 31213388.
      View in: PubMed
    3. Chang CM, Wong HS, Huang CY, Hsu WL, Maio ZF, Chiu SJ, Tsai YT, Chen BK, Wan YY, Wang JY, Chang WC. Functional Effects of let-7g Expression in Colon Cancer Metastasis. Cancers (Basel). 2019 Apr 06; 11(4). PMID: 30959863.
      View in: PubMed
    4. Wan YY, Jena PK. Precision dietary supplementation based on personal gut microbiota. Nat Rev Gastroenterol Hepatol. 2019 Apr; 16(4):204-206. PMID: 30644454.
      View in: PubMed
    5. Lijun Wang, Yu-Jui Yvonne Wan. The role of gut microbiota in liver disease development and treatment. Liver Research. 2019 Mar 1; 3(World J Gastroenterol 21 2015):3-18.
      View in: Publisher Site
    6. Mordaunt CE, Kieffer DA, Shibata NM, Czlonkowska A, Litwin T, Weiss KH, Zhu Y, Bowlus CL, Sarkar S, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers. Epigenetics Chromatin. 2019 02 01; 12(1):10. PMID: 30709419.
      View in: PubMed
    7. Yu S, Wu X, Zhou Y, Sheng L, Jena PK, Han D, Wan YJY, Hwang ST. A Western Diet, but Not a High-Fat and Low-Sugar Diet, Predisposes Mice to Enhanced Susceptibility to Imiquimod-Induced Psoriasiform Dermatitis. J Invest Dermatol. 2019 06; 139(6):1404-1407. PMID: 30571973.
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    8. Lili Sheng, Yu-Jui Yvonne Wan. Regulation of bile acid receptor activity. Liver Research. 2018 Dec 1; 2(Curr Opin Gastroenterol 31 2015):180-185.
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    9. Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease. Hum Mol Genet. 2018 11 15; 27(22):3854-3869. PMID: 30010856.
      View in: PubMed
    10. Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG. Ga12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602. PMID: 30300140.
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    11. Hu Y, French SW, Chau T, Liu HX, Sheng L, Wei F, Stondell J, Garcia JC, Du Y, Bowlus CL, Wan YY. RARß acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells. FASEB J. 2019 02; 33(2):2314-2326. PMID: 30252536.
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    12. Sheng L, Jena PK, Liu HX, Hu Y, Nagar N, Bronner DN, Settles ML, Bäumler AJ, Wan YY. Obesity treatment by epigallocatechin-3-gallate-regulated bile acid signaling and its enriched Akkermansia muciniphila. FASEB J. 2018 Jun 08; fj201800370R. PMID: 29882708.
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    13. Jena PK, Sheng L, Di Lucente J, Jin LW, Maezawa I, Wan YY. Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity. FASEB J. 2018 05; 32(5):2866-2877. PMID: 29401580.
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    14. Sheng L, Jena PK, Hu Y, Liu HX, Nagar N, Kalanetra KM, French SW, French SW, Mills DA, Wan YY. Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation. J Pathol. 2017 12; 243(4):431-441. PMID: 28892150.
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    15. Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY. Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment. Am J Pathol. 2017 Aug; 187(8):1800-1813. PMID: 28711154.
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    16. Liu H, Chen Z, Jin W, Barve A, Wan YY, Cheng K. Silencing of a-complex protein-2 reverses alcohol- and cytokine-induced fibrogenesis in hepatic stellate cells. Liver Res. 2017 Jun; 1(1):70-79. PMID: 28966795.
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    17. Sheng L, Jena PK, Liu HX, Kalanetra KM, Gonzalez FJ, French SW, Krishnan VV, Mills DA, Wan YY. Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation. Sci Rep. 2017 05 11; 7(1):1748. PMID: 28496104.
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    18. van Draanen J, Davidson P, Bour-Jordan H, Bowman-Carpio L, Boyle D, Dubinett S, Gardner B, Gardner J, McFall C, Mercola D, Nakazono T, Soares S, Stoppler H, Tempero M, Vandenberg S, Wan YJ, Dry S. Assessing Researcher Needs for a Virtual Biobank. Biopreserv Biobank. 2017 Jun; 15(3):203-210. PMID: 27929677.
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    19. Li YY, Ge QX, Cao J, Zhou YJ, Du YL, Shen B, Wan YJ, Nie YQ. Association of Fusobacterium nucleatum infection with colorectal cancer in Chinese patients. World J Gastroenterol. 2016 Mar 21; 22(11):3227-33. PMID: 27004000.
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    20. Liu HX, Rocha CS, Dandekar S, Wan YJ. Functional analysis of the relationship between intestinal microbiota and the expression of hepatic genes and pathways during the course of liver regeneration. J Hepatol. 2016 Mar; 64(3):641-50. PMID: 26453969.
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    21. Liu HX, Hu Y, Wan YJ. Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. Oncotarget. 2016 Jan 12; 7(2):1096-106. PMID: 26701854.
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    22. Zhang X, Feng M, Liu X, Bai L, Kong M, Chen Y, Zheng S, Liu S, Wan YJ, Duan Z, Han YP. Persistence of cirrhosis is maintained by intrahepatic regulatory T cells that inhibit fibrosis resolution by regulating the balance of tissue inhibitors of metalloproteinases and matrix metalloproteinases. Transl Res. 2016 Mar; 169:67-79.e1-2. PMID: 26613891.
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    23. Liu HX, Keane R, Sheng L, Wan YJ. Implications of microbiota and bile acid in liver injury and regeneration. J Hepatol. 2015 Dec; 63(6):1502-10. PMID: 26256437.
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    24. Yang F, Hu Y, Liu HX, Wan YJ. MiR-22-silenced cyclin A expression in colon and liver cancer cells is regulated by bile acid receptor. J Biol Chem. 2015 Mar 06; 290(10):6507-15. PMID: 25596928.
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    25. Liu HX, Hu Y, French SW, Gonzalez FJ, Wan YJ. Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARa(PAC) mice due to dysregulated bile acid synthesis. Oncotarget. 2015; 6(12):9686-700. PMID: 25991671.
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    26. Eun JR, Jung YJ, Zhang Y, Zhang Y, Tschudy-Seney B, Ramsamooj R, Wan YJ, Theise ND, Zern MA, Duan Y. Hepatoma SK Hep-1 cells exhibit characteristics of oncogenic mesenchymal stem cells with highly metastatic capacity. PLoS One. 2014; 9(10):e110744. PMID: 25338121.
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    27. Hu Y, Zhan Q, Liu HX, Chau T, Li Y, Wan YJ, Yvonne Wan YJ. Accelerated partial hepatectomy-induced liver cell proliferation is associated with liver injury in Nur77 knockout mice. Am J Pathol. 2014 Dec; 184(12):3272-83. PMID: 25307349.
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    28. Hu Y, Chau T, Liu HX, Liao D, Keane R, Nie Y, Yang H, Wan YJ. Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis. Mol Cancer Res. 2015 Feb; 13(2):281-92. PMID: 25232032.
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    29. Zhan L, Liu HX, Fang Y, Kong B, He Y, Zhong XB, Fang J, Wan YJ, Guo GL. Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes. PLoS One. 2014; 9(9):e105930. PMID: 25198545.
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    30. Yang F, He Y, Liu HX, Tsuei J, Jiang X, Yang L, Wang ZT, Wan YJ. All-trans retinoic acid regulates hepatic bile acid homeostasis. Biochem Pharmacol. 2014 Oct 15; 91(4):483-9. PMID: 25175738.
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    31. Aizhen Xiong, Fan Yang, Lianxiang Fang, Li Yang, Yuqi He, Yu-Jui Yvonne Wan, Ying Xu, Meng Qi, Xiuli Wang, Kate Yu, Karl Wah-Keung Tsim, Zhengtao Wang. Correction to Metabolomic and Genomic Evidence for Compromised Bile Acid Homeostasis by Senecionine, a Hepatotoxic Pyrrolizidine Alkaloid. Chemical Research in Toxicology. 2014 Aug 18; 27(8):1458-1458.
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    32. Liu HX, Ly I, Hu Y, Wan YJ. Retinoic acid regulates cell cycle genes and accelerates normal mouse liver regeneration. Biochem Pharmacol. 2014 Sep 15; 91(2):256-65. PMID: 25087568.
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    33. Tsuei J, Chau T, Mills D, Wan YJ. Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer. Exp Biol Med (Maywood). 2014 Nov; 239(11):1489-504. PMID: 24951470.
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    34. He Y, Tsuei J, Wan YJ. Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15; 307(2):G205-18. PMID: 24833708.
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    35. Nie YQ, Cao J, Zhou YJ, Liang X, Du YL, Wan YJ, Li YY. The effect of miRNA-122 in regulating fat deposition in a cell line model. J Cell Biochem. 2014 May; 115(5):839-46. PMID: 24288170.
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    36. Xiong A, Yang F, Fang L, Yang L, He Y, Wan YJ, Wan YY, Xu Y, Qi M, Wang X, Yu K, Tsim KW, Wang Z. Metabolomic and genomic evidence for compromised bile acid homeostasis by senecionine, a hepatotoxic pyrrolizidine alkaloid. Chem Res Toxicol. 2014 May 19; 27(5):775-86. PMID: 24641316.
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    37. Dunn W, O'Neil M, Zhao J, Wu CH, Roberts B, Chakraborty S, Sherman C, Weaver B, Taylor R, Olson J, Olyaee M, Gilroy R, Schmitt T, Wan YJ, Weinman SA. Donor PNPLA3 rs738409 genotype affects fibrosis progression in liver transplantation for hepatitis C. Hepatology. 2014 Feb; 59(2):453-60. PMID: 24123231.
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    38. He Y, Gong L, Fang Y, Zhan Q, Liu HX, Lu Y, Guo GL, Lehman-McKeeman L, Fang J, Wan YJ. The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling. BMC Genomics. 2013 Aug 28; 14:575. PMID: 23981290.
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    39. Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res. 2013 Aug; 57(8):1319-35. PMID: 23818328.
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    40. Liu HX, Fang Y, Hu Y, Gonzalez FJ, Fang J, Wan YJ. PPARß Regulates Liver Regeneration by Modulating Akt and E2f Signaling. PLoS One. 2013; 8(6):e65644. PMID: 23823620.
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    41. Khan R, Zahid S, Wan YJ, Forster J, Karim AB, Nawabi AM, Azhar A, Rahman MA, Ahmed N. Protein expression profiling of nuclear membrane protein reveals potential biomarker of human hepatocellular carcinoma. Clin Proteomics. 2013 Jun 01; 10(1):6. PMID: 23724895.
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    42. Yang H, Zhong Y, Xie H, Lai X, Xu M, Nie Y, Liu S, Wan YJ. Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. Biochem Pharmacol. 2013 Jun 15; 85(12):1761-9. PMID: 23643933.
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    43. Poland RE, Lesser IM, Wan YJ, Gertsik L, Yao J, Raffel LJ, Lin KM, Myers HF. Response to citalopram is not associated with SLC6A4 genotype in African-Americans and Caucasians with major depression. Life Sci. 2013 May 30; 92(20-21):967-70. PMID: 23562852.
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    44. Raglow Z, Thoma-Perry C, Gilroy R, Wan YJ. IL28B genotype and the expression of ISGs in normal liver. Liver Int. 2013 Aug; 33(7):991-8. PMID: 23522062.
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    45. Hu Y, Liu HX, He Y, Fang Y, Fang J, Wan YJ. Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells. Biochem Pharmacol. 2013 Apr 01; 85(7):1007-17. PMID: 23396089.
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    46. Fang Y, Liu HX, Zhang N, Guo GL, Wan YJ, Fang J. NURBS: a database of experimental and predicted nuclear receptor binding sites of mouse. Bioinformatics. 2013 Jan 15; 29(2):295-7. PMID: 23196988.
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    47. Zhan Q, Fang Y, He Y, Liu HX, Fang J, Wan YJ. Function annotation of hepatic retinoid x receptor a based on genome-wide DNA binding and transcriptome profiling. PLoS One. 2012; 7(11):e50013. PMID: 23166811.
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    48. Yang F, Xu Y, Xiong A, He Y, Yang L, Wan YJ, Wang Z. Evaluation of the protective effect of Rhei Radix et Rhizoma against a-naphthylisothiocyanate induced liver injury based on metabolic profile of bile acids. J Ethnopharmacol. 2012 Dec 18; 144(3):599-604. PMID: 23058990.
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    49. Wei YM, Du YL, Nie YQ, Li YY, Wan YJ. Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans. World J Gastroenterol. 2012 Oct 07; 18(37):5276-82. PMID: 23066323.
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    50. Dunn W, Zeng Z, O'Neil M, Zhao J, Whitener M, Yu-Jui Wan Y, Mitchell EK, Handler M, Weinman SA. The interaction of rs738409, obesity, and alcohol: a population-based autopsy study. Am J Gastroenterol. 2012 Nov; 107(11):1668-74. PMID: 23032985.
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    51. Cao CY, Li YY, Zhou YJ, Nie YQ, Wan YJ. The C-681G polymorphism of the PPAR-? gene is associated with susceptibility to non-alcoholic fatty liver disease. Tohoku J Exp Med. 2012 08; 227(4):253-62. PMID: 22820754.
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    52. Wu C, Gilroy R, Taylor R, Olyaee M, Abdulkarim B, Forster J, O'Neil M, Damjanov I, Wan YJ. Alteration of hepatic nuclear receptor-mediated signaling pathways in hepatitis C virus patients with and without a history of alcohol drinking. Hepatology. 2011 Dec; 54(6):1966-74. PMID: 21898497.
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    53. Kosters A, Tian F, Wan YJ, Wan YY, Karpen SJ. Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-a signalling during inflammation. Liver Int. 2012 Feb; 32(2):321-30. PMID: 22098603.
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    54. Kay HY, Kim WD, Hwang SJ, Choi HS, Gilroy RK, Wan YJ, Kim SG. Nrf2 inhibits LXRa-dependent hepatic lipogenesis by competing with FXR for acetylase binding. Antioxid Redox Signal. 2011 Oct 15; 15(8):2135-46. PMID: 21504366.
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    55. Shukla RS, Qin B, Wan YJ, Cheng K. PCBP2 siRNA reverses the alcohol-induced pro-fibrogenic effects in hepatic stellate cells. Pharm Res. 2011 Dec; 28(12):3058-68. PMID: 21643860.
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    56. Raglow Z, Thoma-Perry C, Gilroy R, Wan YJ. The interaction between HCV and nuclear receptor-mediated pathways. Pharmacol Ther. 2011 Oct; 132(1):30-8. PMID: 21620888.
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    57. Du Y, Nie Y, Li Y, Wan YJ. The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis. Alcohol Clin Exp Res. 2011 Sep; 35(9):1625-34. PMID: 21554332.
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    58. Yang H, Zhan Q, Wan YJ. Enrichment of Nur77 mediated by retinoic acid receptor ß leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors. Hepatology. 2011 Mar; 53(3):865-74. PMID: 21319187.
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    59. Yang H, Nie Y, Li Y, Wan YJ. ERK1/2 deactivation enhances cytoplasmic Nur77 expression level and improves the apoptotic effect of fenretinide in human liver cancer cells. Biochem Pharmacol. 2011 Apr 01; 81(7):910-6. PMID: 21241664.
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    60. Razny U, Wator L, Polus A, Kiec-Wilk B, Wan YJ, Dyduch G, Tomaszewska R, Dembinska-Kiec A. Modulatory effect of high saturated fat diet-induced metabolic disturbances on angiogenic response in hepatocyte RXRa knockout mice. Pharmacol Rep. 2010 Nov-Dec; 62(6):1078-89. PMID: 21273665.
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    61. Bushue N, Wan YJ. Retinoid pathway and cancer therapeutics. Adv Drug Deliv Rev. 2010 Oct 30; 62(13):1285-98. PMID: 20654663.
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    62. Gyamfi MA, Wan YJ. Pathogenesis of alcoholic liver disease: the role of nuclear receptors. Exp Biol Med (Maywood). 2010 May; 235(5):547-60. PMID: 20463294.
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    63. Du Y, Yang M, Yeh HW, Wan YJ. The association of exon 3 VNTR polymorphism of the dopamine receptor D4 (DRD4) gene with alcoholism in Mexican Americans. Psychiatry Res. 2010 May 30; 177(3):358-60. PMID: 20359751.
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    64. Yang H, Nie Y, Li Y, Wan YJ. Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells. Exp Biol Med (Maywood). 2010 Jan; 235(1):32-9. PMID: 20404016.
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    65. Yang X, Guo M, Wan YJ. Deregulation of growth factor, circadian clock, and cell cycle signaling in regenerating hepatocyte RXRalpha-deficient mouse livers. Am J Pathol. 2010 Feb; 176(2):733-43. PMID: 20035057.
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    66. Wang K, Damjanov I, Wan YJ. The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury. Lab Invest. 2010 Feb; 90(2):257-65. PMID: 19997066.
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    67. Bushue N, Wan YY. Retinoic Acid-mediated Nuclear Receptor Activation and Hepatocyte Proliferation. J Exp Clin Med. 2009 Dec; 1(1):23-30. PMID: 27635169.
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    68. Yang H, Bushue N, Bu P, Wan YJ. Induction and intracellular localization of Nur77 dictate fenretinide-induced apoptosis of human liver cancer cells. Biochem Pharmacol. 2010 Apr 01; 79(7):948-54. PMID: 19912993.
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    69. Du Y, Wan YJ. The interaction of reward genes with environmental factors in contribution to alcoholism in mexican americans. Alcohol Clin Exp Res. 2009 Dec; 33(12):2103-12. PMID: 19764934.
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    70. Chen S, Wang K, Wan YJ. Retinoids activate RXR/CAR-mediated pathway and induce CYP3A. Biochem Pharmacol. 2010 Jan 15; 79(2):270-6. PMID: 19686701.
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    71. Wei Y, Nie Y, Lai J, Wan YJ, Li Y. Comparison of the population capacity of hematopoietic and mesenchymal stem cells in experimental colitis rat model. Transplantation. 2009 Jul 15; 88(1):42-8. PMID: 19584679.
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    72. Razny U, Wator L, Polus A, Wan YJ, Dyduch G, Tomaszewska R, Dembinska-Kiec A. Hepatocyte RXR alpha deletion in mice leads to inhibition of angiogenesis. Genes Nutr. 2009 Mar; 4(1):69-72. PMID: 19224264.
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    73. Gyamfi MA, Wan YJ. Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis. J Biol Chem. 2009 Apr 03; 284(14):9321-30. PMID: 19176532.
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    74. Yang X, Zhang YK, Esterly N, Klaassen CD, Wan YJ. Gender disparity of hepatic lipid homoeostasis regulated by the circadian clock. J Biochem. 2009 May; 145(5):609-23. PMID: 19174548.
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    75. Yang D, Pearce RE, Wang X, Gaedigk R, Wan YJ, Yan B. Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. Biochem Pharmacol. 2009 Jan 15; 77(2):238-47. PMID: 18983829.
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    76. Gyamfi MA, Tanaka Y, He L, Klaassen CD, Wan YJ. Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice. Toxicol Appl Pharmacol. 2009 Jan 15; 234(2):166-78. PMID: 18952117.
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    77. Guo M, Gong L, He L, Lehman-McKeeman L, Wan YJ. Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific manner. BMC Genomics. 2008 Aug 28; 9:403. PMID: 18755030.
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    78. Dai G, He L, Bu P, Wan YJ. Pregnane X receptor is essential for normal progression of liver regeneration. Hepatology. 2008 Apr; 47(4):1277-87. PMID: 18167061.
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    79. Wang K, Wan YJ. Nuclear receptors and inflammatory diseases. Exp Biol Med (Maywood). 2008 May; 233(5):496-506. PMID: 18375823.
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    80. Wang K, Chen S, Xie W, Wan YJ. Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway. Biochem Pharmacol. 2008 Jun 01; 75(11):2204-13. PMID: 18400206.
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    81. Wortham M, He L, Gyamfi M, Copple BL, Wan YJ. The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Dig Dis Sci. 2008 Oct; 53(10):2761-74. PMID: 18299981.
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    82. Lin KM, Perlis RH, Wan YJ. Pharmacogenomic strategy for individualizing antidepressant therapy. Dialogues Clin Neurosci. 2008; 10(4):401-8. PMID: 19170397.
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    83. Bu P, Wan YJ. Fenretinide-induced apoptosis of Huh-7 hepatocellular carcinoma is retinoic acid receptor beta dependent. BMC Cancer. 2007 Dec 31; 7:236. PMID: 18166136.
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    84. Yang M, Tsuang J, Wan YJ. A haplotype analysis of CYP2E1 polymorphisms in relation to alcoholic phenotypes in Mexican Americans. Alcohol Clin Exp Res. 2007 Dec; 31(12):1991-2000. PMID: 18034693.
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    85. Gyamfi MA, He L, French SW, Damjanov I, Wan YJ. Hepatocyte retinoid X receptor alpha-dependent regulation of lipid homeostasis and inflammatory cytokine expression contributes to alcohol-induced liver injury. J Pharmacol Exp Ther. 2008 Feb; 324(2):443-53. PMID: 17975011.
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    86. Gyamfi MA, Damjanov I, French S, Wan YJ. The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury. Biochem Pharmacol. 2008 Feb 15; 75(4):981-95. PMID: 18036573.
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    87. Wortham M, Czerwinski M, He L, Parkinson A, Wan YJ. Expression of constitutive androstane receptor, hepatic nuclear factor 4 alpha, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver. Drug Metab Dispos. 2007 Sep; 35(9):1700-10. PMID: 17576804.
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    88. Nakamoto K, Kidd JR, Jenison RD, Klaassen CD, Wan YJ, Kidd KK, Zhong XB. Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips. Pharmacogenet Genomics. 2007 Feb; 17(2):103-14. PMID: 17301690.
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    89. Huai-Rong Luo, Yu-Jui Yvonne Wan. Polymorphisms of Genes Encoding Phase I Enzymes in Mexican Americans – An Ethnic Comparison Study. Current Pharmacogenomics and Personalized Medicine. 2006 Dec 1; 4(4):345-353.
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    90. Huai-Rong Luo, Tamiko Konishi, John Tsuang, Yu-Jui Yvonne Wan. Comparison of Alcohol Drinking Behaviors and Associated Problems Between Benders and Nonbenders in Mexican Americans Who Drink Excessively. Addictive Disorders & Their Treatment. 2006 Sep 1; 5(3):121-127.
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    91. Gyamfi MA, Kocsis MG, He L, Dai G, Mendy AJ, Wan YJ. The role of retinoid X receptor alpha in regulating alcohol metabolism. J Pharmacol Exp Ther. 2006 Oct; 319(1):360-8. PMID: 16829625.
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    92. Luo HR, Poland RE, Lin KM, Wan YJ. Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: a cross-ethnic comparative study. Clin Pharmacol Ther. 2006 Jul; 80(1):33-40. PMID: 16815315.
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    93. Nakamoto K, Wang S, Jenison RD, Guo GL, Klaassen CD, Wan YJ, Zhong XB. Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene. BMC Genet. 2006 May 18; 7:29. PMID: 16709249.
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    94. Wang K, Mendy AJ, Dai G, Luo HR, He L, Wan YJ. Retinoids activate the RXR/SXR-mediated pathway and induce the endogenous CYP3A4 activity in Huh7 human hepatoma cells. Toxicol Sci. 2006 Jul; 92(1):51-60. PMID: 16632523.
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    95. Dai G, He L, Chou N, Wan YJ. Acetaminophen metabolism does not contribute to gender difference in its hepatotoxicity in mouse. Toxicol Sci. 2006 Jul; 92(1):33-41. PMID: 16611625.
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    96. Gyamfi MA, Wan YJ. The effect of ethanol, ethanol metabolizing enzyme inhibitors, and Vitamin E on regulating glutathione, glutathione S-transferase, and S-adenosylmethionine in mouse primary hepatocyte. Hepatol Res. 2006 May; 35(1):53-61. PMID: 16540368.
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    97. Wan YJ, Badr MZ. Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X ReceptorAlpha. PPAR Res. 2006; 2006:96341. PMID: 17259670.
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    98. Luo HR, Gaedigk A, Aloumanis V, Wan YJ. Identification of CYP2D6 impaired functional alleles in Mexican Americans. Eur J Clin Pharmacol. 2005 Dec; 61(11):797-802. PMID: 16283274.
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    99. Dai G, Chou N, He L, Gyamfi MA, Mendy AJ, Slitt AL, Klaassen CD, Wan YJ. Retinoid X receptor alpha Regulates the expression of glutathione s-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver. Mol Pharmacol. 2005 Dec; 68(6):1590-6. PMID: 16157696.
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    100. Dai G, Wan YJ. Animal models of xenobiotic receptors. Curr Drug Metab. 2005 Aug; 6(4):341-55. PMID: 16101573.
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    101. Luo HR, Hou ZF, Wu J, Zhang YP, Wan YJ. Evolution of the DRD2 gene haplotype and its association with alcoholism in Mexican Americans. Alcohol. 2005 Jun; 36(2):117-25. PMID: 16396745.
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    102. Chuang KH, Lee YF, Lin WJ, Chu CY, Altuwaijri S, Wan YJ, Chang C. 9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor. Mol Endocrinol. 2005 May; 19(5):1200-12. PMID: 15650026.
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    103. Konishi T, Luo HR, Calvillo M, Mayo MS, Lin KM, Wan YJ. ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles. Alcohol Clin Exp Res. 2004 Aug; 28(8):1145-52. PMID: 15318112.
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    104. Wu Y, Zhang X, Bardag-Gorce F, Robel RC, Aguilo J, Chen L, Zeng Y, Hwang K, French SW, Lu SC, Wan YJ. Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver. Mol Pharmacol. 2004 Mar; 65(3):550-7. PMID: 14978233.
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    105. Ai-She Leng, Maria Calvillo, Tamiko Konishi, Gloria D. Guzman, Elberth Pineda, Keh-Ming Lin, John Tsuang, Yu-Jui Yvonne Wan. Characteristics and Drinking Patterns in Alcohol Abusing Mexican American Men. Addictive Disorders & Their Treatment. 2004 Mar 1; 3(1):14-17.
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    106. Wu Y, Cai Y, Aguilo J, Dai T, Ao Y, Wan YJ. RXRalpha mRNA expression is associated with cell proliferation and cell cycle regulation in Hep3B cell. Exp Mol Pathol. 2004 Feb; 76(1):24-8. PMID: 14738865.
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    107. Luo HR, Aloumanis V, Lin KM, Gurwitz D, Wan YJ. Polymorphisms of CYP2C19 and CYP2D6 in Israeli ethnic groups. Am J Pharmacogenomics. 2004; 4(6):395-401. PMID: 15651900.
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    108. Konishi T, Calvillo M, Leng AS, Lin KM, Wan YJ. Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-Americans. Alcohol. 2004 Jan; 32(1):45-52. PMID: 15066703.
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    109. Dai T, Wu Y, Leng AS, Ao Y, Robel RC, Lu SC, French SW, Wan YJ. RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity. Exp Mol Pathol. 2003 Dec; 75(3):194-200. PMID: 14611810.
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    110. Cherrington NJ, Slitt AL, Maher JM, Zhang XX, Zhang J, Huang W, Wan YJ, Moore DD, Klaassen CD. Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor. Drug Metab Dispos. 2003 Nov; 31(11):1315-9. PMID: 14570762.
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    111. Perlis RH, Mischoulon D, Smoller JW, Wan YJ, Lamon-Fava S, Lin KM, Rosenbaum JF, Fava M. Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment. Biol Psychiatry. 2003 Nov 01; 54(9):879-83. PMID: 14573314.
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    112. Cai Y, Dai T, Ao Y, Konishi T, Chuang KH, Lue Y, Chang C, Wan YJ. Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice. Endocrinology. 2003 Jun; 144(6):2311-8. PMID: 12746291.
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    113. Konishi T, Calvillo M, Leng AS, Feng J, Lee T, Lee H, Smith JL, Sial SH, Berman N, French S, Eysselein V, Lin KM, Wan YJ. The ADH3*2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men. Exp Mol Pathol. 2003 Apr; 74(2):183-9. PMID: 12710951.
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    114. Bentinger M, Turunen M, Zhang XX, Wan YJ, Dallner G. Involvement of retinoid X receptor alpha in coenzyme Q metabolism. J Mol Biol. 2003 Feb 21; 326(3):795-803. PMID: 12581641.
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    115. Wan YJ, Han G, Cai Y, Dai T, Konishi T, Leng AS. Hepatocyte retinoid X receptor-alpha-deficient mice have reduced food intake, increased body weight, and improved glucose tolerance. Endocrinology. 2003 Feb; 144(2):605-11. PMID: 12538623.
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    116. Konishi T, Smith JL, Lin KM, Wan YJ. Influence of genetic admixture on polymorphisms of alcohol-metabolizing enzymes: analyses of mutations on the CYP2E1, ADH2, ADH3 and ALDH2 genes in a Mexican-American population living in the Los Angeles area. Alcohol Alcohol. 2003 Jan-Feb; 38(1):93-4. PMID: 12554615.
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    117. Sokol RZ, Wang S, Wan YJ, Stanczyk FZ, Gentzschein E, Chapin RE. Long-term, low-dose lead exposure alters the gonadotropin-releasing hormone system in the male rat. Environ Health Perspect. 2002 Sep; 110(9):871-4. PMID: 12204820.
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    118. Cai Y, Konishi T, Han G, Campwala KH, French SW, Wan YJ. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways. Eur J Pharm Sci. 2002 Feb; 15(1):89-96. PMID: 11803135.
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    119. Mendoza R, Wan YJ, Poland RE, Smith M, Zheng Y, Berman N, Lin KM. CYP2D6 polymorphism in a Mexican American population. Clin Pharmacol Ther. 2001 Dec; 70(6):552-60. PMID: 11753272.
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    120. Kumar R, Advani AR, Sharan J, Basharutallah MS, Al-Lumai AS. Pregnancy induced hemolytic anemia: an unexplained entity. Ann Hematol. 2001 Oct; 80(10):623-6. PMID: 11732878.
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    121. Wan YJ, Poland RE, Han G, Konishi T, Zheng YP, Berman N, Lin KM. Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in southern California. Pharmacogenetics. 2001 Aug; 11(6):489-99. PMID: 11505219.
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    122. Bardag-Gorce F, French BA, Lue YH, Nguyen V, Wan YJ, French SW. Mallory bodies formed in proteasome-depleted hepatocytes: an immunohistochemical study. Exp Mol Pathol. 2001 Feb; 70(1):7-18. PMID: 11170786.
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    123. Wan YY, Cai Y, Li J, Yuan Q, French B, Gonzalez FJ, French S. Regulation of peroxisome proliferator activated receptor alpha-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice. Hepatol Res. 2001 Feb; 19(2):117-130. PMID: 11164737.
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    124. Yuan QX, Nagao Y, French BA, Wan YJ, French SW. Dexamethasone enhances mallory body formation in drug-primed mouse liver. Exp Mol Pathol. 2000 Dec; 69(3):202-10. PMID: 11115361.
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    125. Poland RE, Pechnick RN, Cloak CC, Wan YJ, Nuccio I, Lin KM. Effect of cigarette smoking on coumarin metabolism in humans. Nicotine Tob Res. 2000 Nov; 2(4):351-4. PMID: 11197315.
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    126. Qian A, Cai Y, Magee TR, Wan YJ. Identification of retinoic acid-responsive elements on the HNF1alpha and HNF4alpha genes. Biochem Biophys Res Commun. 2000 Oct 05; 276(3):837-42. PMID: 11027556.
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    127. Wan YJ, Cai Y, Lungo W, Fu P, Locker J, French S, Sucov HM. Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice. J Biol Chem. 2000 Sep 08; 275(36):28285-90. PMID: 10866995.
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    128. Wan YJ, An D, Cai Y, Repa JJ, Hung-Po Chen T, Flores M, Postic C, Magnuson MA, Chen J, Chien KR, French S, Mangelsdorf DJ, Sucov HM. Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver. Mol Cell Biol. 2000 Jun; 20(12):4436-44. PMID: 10825207.
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    129. Wan YJ, Cai Y, Cowan C, Magee TR. Fatty acyl-CoAs inhibit retinoic acid-induced apoptosis in Hep3B cells. Cancer Lett. 2000 Jun 01; 154(1):19-27. PMID: 10799735.
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    130. Yu-Jui Yvonne Wan, Yan Cai, Catherine Cowan. Hepatocyte nuclear factor 1 mediates the cell density associated induction of the a-fetoprotein gene. Hepatology Research. 2000 Feb 1; 16(3):195-210.
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    131. Gouillon ZQ, Miyamoto K, Donohue TM, Wan YJ, French BA, Nagao Y, Fu P, Reitz RC, Hagbjork A, Yap C, Yuan QX, Ingelman-Sundberg M, French SW. Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway. Front Biosci. 1999 Sep 01; 4:A16-25. PMID: 10477671.
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    132. Magee TR, Cai Y, El-Houseini ME, Locker J, Wan YJ. Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors. J Biol Chem. 1998 Nov 06; 273(45):30024-32. PMID: 9792724.
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    133. Nagao Y, French BA, Cai Y, French SW, Wan YJ. Inhibition of PPAR alpha/RXR alpha-mediated direct hyperplasia pathways during griseofulvin-induced hepatocarcinogenesis. J Cell Biochem. 1998 May 01; 69(2):189-200. PMID: 9548566.
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    134. Li C, Wan YJ. Differentiation and antiproliferation effects of retinoic acid receptor beta in hepatoma cells. Cancer Lett. 1998 Feb 27; 124(2):205-11. PMID: 9500212.
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    135. Wan YJ, Cai Y, Magee TR. Retinoic acid differentially regulates retinoic acid receptor-mediated pathways in the Hep3B cell line. Exp Cell Res. 1998 Jan 10; 238(1):241-7. PMID: 9457077.
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    136. Zhang-Gouillon ZQ, Yuan QX, Hu B, Marceau N, French BA, Gaal K, Nagao Y, Wan YJ, French SW. Mallory body formation by ethanol feeding in drug-primed mice. Hepatology. 1998 Jan; 27(1):116-22. PMID: 9425926.
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    137. Wan YJ, Poland RE, Lin KM. Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans. Genet Test. 1998; 2(1):79-83. PMID: 10464602.
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    138. Sawicki M, Arnold E, Ebrahimi S, Duell T, Jin S, Wood T, Chakrabarti R, Peters J, Wan Y, Samara G, Weier HU, Udar N, Passaro E, Srivatsan ES. A transcript map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13. Genomics. 1997 Jun 15; 42(3):405-12. PMID: 9205112.
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    139. Eubanks PJ, Sawicki MP, Samara GJ, Wan YJ, Gatti RA, Hurwitz M, Passaro E. Pancreatic endocrine tumors with loss of heterozygosity at the multiple endocrine neoplasia type I locus. Am J Surg. 1997 Jun; 173(6):518-20. PMID: 9207166.
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    140. Lin HJ, French SW, Reichenbach D, Wan YJ, Passaro E, Sawicki MP. Novel p53 mutation in a malignant tumor secreting vasoactive intestinal peptide. Arch Pathol Lab Med. 1997 Feb; 121(2):125-8. PMID: 9126038.
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    141. Wood TF, Srivatsan ES, Chakrabarti R, Ma GC, Kuan N, Samara GJ, Higgins MJ, Shows TB, Johnson CL, Wan YJ, Passaro EP, Sawicki MP. A 1.5-megabase physical map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13. Genomics. 1996 Dec 01; 38(2):166-73. PMID: 8954798.
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    142. Li C, Locker J, Wan YJ. RXR-mediated regulation of the alpha-fetoprotein gene through an upstream element. DNA Cell Biol. 1996 Nov; 15(11):955-63. PMID: 8945636.
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    143. Wan YJ, Wang L, Wu TC. Murine endodermal F9E cells, derived from the teratocarcinoma line F9, contain high basal levels of retinoic acid receptors (RARs and RXRs) but are not sensitive to the actions of retinoic acid. Differentiation. 1996 Jul; 60(4):211-8. PMID: 8765051.
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    144. Lin KM, Poland RE, Wan YJ, Smith MW, Lesser IM. The evolving science of pharmacogenetics: clinical and ethnic perspectives. Psychopharmacol Bull. 1996; 32(2):205-17. PMID: 8783890.
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    145. Peng SK, Zhang X, Chai NN, Wan Y, Morin RJ. Inhibitory effect of cholesterol oxides on low density lipoprotein receptor gene expression. Artery. 1996; 22(2):61-79. PMID: 8864249.
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    146. Wan YJ, Wang L, Wu TC. Different response to retinoic acid of two teratocarcinoma cell lines. Exp Cell Res. 1995 Aug; 219(2):392-8. PMID: 7543852.
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    147. Morimoto M, Hagbjörk AL, Wan YJ, Fu PC, Clot P, Albano E, Ingelman-Sundberg M, French SW. Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors. Hepatology. 1995 Jun; 21(6):1610-7. PMID: 7768506.
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    148. Wan YJ, Wang L, Wu TC. Retinoic acid induces activin receptor IIB mRNA in F9 embryonal carcinoma cells. J Mol Endocrinol. 1995 Apr; 14(2):247-54. PMID: 7619212.
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    149. Wan YJ, Pan T, Wang L, Locker J, Wu TC. 9-cis-retinoic acid is more effective than all-trans-retinoic acid in upregulating expression of the alpha-fetoprotein gene. J Mol Endocrinol. 1995 Feb; 14(1):101-8. PMID: 7539613.
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    150. Wan YJ, Morimoto M, Thurman RG, Bojes HK, French SW. Expression of the peroxisome proliferator-activated receptor gene is decreased in experimental alcoholic liver disease. Life Sci. 1995; 56(5):307-17. PMID: 7837930.
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    151. Wu TC, Jih MH, Wang L, Wan YJ. Expression of activin receptor II and IIB mRNA isoforms in mouse reproductive organs and oocytes. Mol Reprod Dev. 1994 May; 38(1):9-15. PMID: 8049070.
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    152. Klein D, Wan YJ, Kamyab S, Okuda H, Sokol RZ. Effects of toxic levels of lead on gene regulation in the male axis: increase in messenger ribonucleic acids and intracellular stores of gonadotrophs within the central nervous system. Biol Reprod. 1994 Apr; 50(4):802-11. PMID: 8199261.
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    153. Wan YJ, Wang L, Wu TC. Dexamethasone increases the expression of retinoid X receptor genes in rat hepatoma cell lines. Lab Invest. 1994 Apr; 70(4):547-52. PMID: 8176893.
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    154. Wan YJ, Wang L, Wu TC. The expression of retinoid X receptor genes is regulated by all-trans- and 9-cis-retinoic acid in F9 teratocarcinoma cells. Exp Cell Res. 1994 Jan; 210(1):56-61. PMID: 8269997.
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    155. Eubanks PJ, Sawicki MP, Samara GJ, Gatti R, Nakamura Y, Tsao D, Johnson C, Hurwitz M, Wan YJ, Passaro E. Putative tumor-suppressor gene on chromosome 11 is important in sporadic endocrine tumor formation. Am J Surg. 1994 Jan; 167(1):180-5. PMID: 7906100.
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    156. Jih MH, Lu JK, Wan YJ, Wu TC. Enhanced ovarian inhibin subunit gene expression in aging rats is due to chronic anovulation. Biol Reprod. 1993 Dec; 49(6):1208-14. PMID: 8286603.
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    157. Heiner JS, Wang L, Rutgers JK, Wan YJ, Cai L, Wu TC. Endometrial expression of mRNA encoding epidermal growth factor receptor in normal and leiomyomatous uteri throughout the menstrual cycle. Am J Reprod Immunol. 1993 Sep-Oct; 30(2-3):68-73. PMID: 8311933.
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    158. Wan YJ. Retinoic acid and its receptors. Am J Surg. 1993 Jul; 166(1):50-3. PMID: 8392301.
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    159. Wu TC, Lee SM, Jih MH, Liu JT, Wan YJ. Differential distribution of glycoconjugates in human reproductive tract. Fertil Steril. 1993 Jan; 59(1):60-4. PMID: 8419223.
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    160. Jih MH, Lu JK, Wan YJ, Wu TC. Inhibin subunit gene expression and distribution in the ovaries of immature, young adult, middle-aged, and old female rats. Endocrinology. 1993 Jan; 132(1):319-26. PMID: 8419130.
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    161. Wu TC, Wang L, Wan YJ. Detection of estrogen receptor messenger ribonucleic acid in human oocytes and cumulus-oocyte complexes using reverse transcriptase-polymerase chain reaction. Fertil Steril. 1993 Jan; 59(1):54-9. PMID: 7678235.
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    162. Wan YJ, Wang L, Wu TC. Detection of retinoic acid receptor mRNA in rat tissues by reverse transcriptase-polymerase chain reaction. J Mol Endocrinol. 1992 Dec; 9(3):291-4. PMID: 1282320.
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    163. Wu TC, Wang L, Wan YJ. Expression of estrogen receptor gene in mouse oocyte and during embryogenesis. Mol Reprod Dev. 1992 Dec; 33(4):407-12. PMID: 1472372.
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    164. Wu TC, Wang L, Wan YJ. Retinoic acid regulates gene expression of retinoic acid receptors alpha, beta and gamma in F9 mouse teratocarcinoma cells. Differentiation. 1992 Nov; 51(3):219-24. PMID: 1334013.
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    165. Sawicki MP, Wan YJ, Johnson CL, Berenson J, Gatti R, Passaro E. Loss of heterozygosity on chromosome 11 in sporadic gastrinomas. Hum Genet. 1992 Jun; 89(4):445-9. PMID: 1352275.
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    166. Wan YJ, Wu TC. The effects of retinoic acid on the expression of alpha-fetoprotein and albumin genes in rat hepatoma cell lines. Differentiation. 1992 Jun; 50(2):107-11. PMID: 1379951.
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    167. Wan YJ, Wang L, Wu TC. Expression of retinoic acid receptor genes in developing rat livers and hepatoma cells. Lab Invest. 1992 May; 66(5):646-51. PMID: 1315406.
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    168. Wan YJ, Chou JY. Expression of the alpha-fetoprotein gene in adult rat liver. Arch Biochem Biophys. 1989 Apr; 270(1):267-76. PMID: 2467624.
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    169. Chou JY, Sartwell AD, Wan YJ, Watanabe S. Characterization of pregnancy-specific beta 1-glycoprotein synthesized by human placental fibroblasts. Mol Endocrinol. 1989 Jan; 3(1):89-96. PMID: 2492635.
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    170. Chou JY, Wan YJ. Regulation of expression of the rat alpha-fetoprotein gene. Oxf Surv Eukaryot Genes. 1989; 6:1-31. PMID: 2483617.
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    171. Wan YJ, Jimenez-Molina JL, Chou JY. Fetal and variant alpha-fetoproteins are encoded by mRNAs that differ in sequence at the 5' end. Biochemistry. 1988 Sep 20; 27(19):7269-76. PMID: 2462901.
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    172. Wan YJ, Levi BZ, Ozato K. Induction of c-fos gene expression by interferons. J Interferon Res. 1988 Feb; 8(1):105-12. PMID: 2452846.
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    173. Chou JY, Wan YJ, Sakiyama T. Regulation of rat liver maturation in vitro by glucocorticoids. Mol Cell Biol. 1988 Jan; 8(1):203-9. PMID: 2447484.
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    174. Kasik JW, Wan YJ, Ozato K. A burst of c-fos gene expression in the mouse occurs at birth. Mol Cell Biol. 1987 Sep; 7(9):3349-52. PMID: 3313015.
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    175. Wan YJ, Orrison BM, Lieberman R, Lazarovici P, Ozato K. Induction of major histocompatibility class I antigens by interferons in undifferentiated F9 cells. J Cell Physiol. 1987 Feb; 130(2):276-83. PMID: 3102507.
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    176. Ozato K, Wan YJ, Orrison BM. Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon. Proc Natl Acad Sci U S A. 1985 Apr; 82(8):2427-31. PMID: 2581247.
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    177. Wan YJ, Wu TC, Chung AE, Damjanov I. Monoclonal antibodies to laminin reveal the heterogeneity of basement membranes in the developing and adult mouse tissues. J Cell Biol. 1984 Mar; 98(3):971-9. PMID: 6365932.
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    178. Wu TC, Lee MC, Wan YJ, Damjanov I. Lectin binding sites of the mouse ovary, intraovarian and ovulated ova. Histochemistry. 1984; 80(6):527-33. PMID: 6432745.
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    179. Wu TC, Wan YJ, Chung AE, Damjanov I. Immunohistochemical localization of entactin and laminin in mouse embryos and fetuses. Dev Biol. 1983 Dec; 100(2):496-505. PMID: 6653883.
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    180. Wan YJ, Wu TC, Damjanov I. Immediate and delayed effects of vincristine administered during early postimplantation stages of murine embryogenesis. J Exp Zool. 1983 Jul; 227(1):49-55. PMID: 6619766.
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    181. Lee MC, Wu TC, Wan YJ, Damjanov I. Pregnancy-related changes in the mouse oviduct and uterus revealed by differential binding of fluoresceinated lectins. Histochemistry. 1983; 79(3):365-75. PMID: 6418694.
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    182. Wu TC, Wan YJ, Damjanov I. Fluorescein-conjugated Bandeiraea simplicifolia lectin as a marker of endodermal, yolk sac, and trophoblastic differentiation in the mouse embryo. Differentiation. 1983; 24(1):55-9. PMID: 6409701.
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    183. Wu TC, Wan YJ, Damjanov I. Distribution of Bandeiraea simplicifolia lectin binding sites in the genital organs of female and male mice. Histochemistry. 1983; 77(2):233-41. PMID: 6341328.
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    184. Wan YJ, Wu TC, Damjanov I. Twinning and conjoined placentation in mice. J Exp Zool. 1982 May 20; 221(1):81-6. PMID: 7097179.
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    185. Wan YJ, Wu TC, Damjanov I. Development of early somitic mouse embryos in static culture in vitro. J Exp Zool. 1982 Apr 10; 220(2):219-25. PMID: 7077268.
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    186. Wu TC, Wan YJ, Damjanov I. Mouse egg cylinders developed in vitro may form benign and malignant teratoid tumors. Experientia. 1982 Jan 15; 38(1):128-9. PMID: 7056355.
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    187. Wu TC, Wan YJ, Damjanov I. Positioning of inner cell mass determines the development of mouse blastocysts in vitro. J Embryol Exp Morphol. 1981 Oct; 65:105-17. PMID: 7334294.
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    188. Wu TC, Wan YJ, Damjanov I. Rat serum promotes the in vitro development of mouse blastocysts during early somitic stages of embryogenesis. J Exp Zool. 1981 Sep; 217(3):451-53. PMID: 7338718.
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