Lee-Way Jin

Title(s)Professor, MED: Pathology & Lab Medicine
SchoolSchool of Medicine
AddressM.I.N.D Bldg/UCDMC
CA 95817
Phone916-703-0392
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    Collapse Research 
    Collapse Research Activities and Funding
    Soluble epoxide hydrolase-regulated lipid signaling in Alzheimer?s disease
    NIH RF1AG071665Apr 1, 2021 - Mar 31, 2024
    Role: Co-Principal Investigator
    The potassium channel Kv1.3 in perinatal brain injury
    NIH R01NS110768Mar 15, 2019 - Jan 31, 2024
    Role: Principal Investigator
    Comprehensive Characterization of Glycosylation Alterations in Alzheimer's Disease
    NIH R01AG062240Sep 30, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    Mitochondrial ROS and Microglia in Rett Syndrome
    NIH R01HD088832Aug 10, 2017 - May 31, 2022
    Role: Principal Investigator
    The Microglial Kv1.3 Channel in Alzheimer's Disease
    NIH R21AG038910Aug 1, 2011 - Jun 30, 2013
    Role: Principal Investigator
    The role of astrocytes in Rett syndrome
    NIH R01HD064817Jan 1, 2011 - Dec 31, 2016
    Role: Principal Investigator
    Identify Abeta Oligomer Inhibitors By Combinatorial Chemistry
    NIH R21AG031362Sep 1, 2008 - Aug 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A machine learning approach to automate microinfarct and microhemorrhage screening in hematoxylin and eosin-stained human brain tissues. J Neuropathol Exp Neurol. 2024 Dec 26. Cerny Oliveira L, Chauhan J, Chaudhari A, Cheung SS, Patel V, Villablanca AC, Jin LW, DeCarli C, Chuah CN, Dugger BN. PMID: 39724914.
      View in: PubMed   Mentions:    Fields:    
    2. Unique N-glycosylation signatures in Aβ oligomer- and lipopolysaccharide-activated human iPSC-derived microglia. Res Sq. 2024 Nov 19. Tang X, Schindler R, Lucente J, Oloumi A, Tena J, Harvey D, Lebrilla C, Zivkovic A, Jin LW, Maezawa I. PMID: 39606433; PMCID: PMC11601871.
      View in: PubMed   Mentions:
    3. WMH Contributions to Cognitive Impairment: Rationale and Design of the Diverse VCID Study. Stroke. 2024 Nov 15. DeCarli C, Rajan KB, Jin LW, Hinman J, Johnson DK, Harvey D, Fornage M, Diverse VCID Study Investigators. PMID: 39545328.
      View in: PubMed   Mentions:    Fields:    
    4. The impact of mild episodic ketosis on microglia and hippocampal long-term depression in 5xFAD mice. FASEB Bioadv. 2024 Dec; 6(12):581-596. Di Lucente J, Ramsey JJ, Jin LW, Maezawa I. PMID: 39650227; PMCID: PMC11618890.
      View in: PubMed   Mentions:
    5. Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations. bioRxiv. 2024 Sep 24. Ghandian S, Albarghouthi L, Nava K, Sharma SRR, Minaud L, Beckett L, Saito N, DeCarli C, Rissman RA, Teich AF, Jin LW, Dugger BN, Keiser MJ. PMID: 39386601; PMCID: PMC11463656.
      View in: PubMed   Mentions:
    6. Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups. Acta Neuropathol. 2024 Aug 23; 148(1):27. Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN. PMID: 39177846; PMCID: PMC11343944.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases. Acta Neuropathol Commun. 2024 Aug 17; 12(1):134. Scalco R, Oliveira LC, Lai Z, Harvey DJ, Abujamil L, DeCarli C, Jin LW, Chuah CN, Dugger BN. PMID: 39154006; PMCID: PMC11330038.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2401420121. Panwar A, Rentsendorj A, Jhun M, Cohen RM, Cordner R, Gull N, Pechnick RN, Duvall G, Mardiros A, Golchian D, Schubloom H, Jin LW, Van Dam D, Vermeiren Y, De Reu H, De Deyn PP, Raskatov JA, Black KL, Irvin DK, Williams BA, Wheeler CJ. PMID: 38995966; PMCID: PMC11260139.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    9. Elevated lipopolysaccharide binding protein in Alzheimer's disease patients with APOE3/E3 but not APOE3/E4 genotype. Front Neurol. 2024; 15:1408220. Romo EZ, Hong BV, Patel RY, Agus JK, Harvey DJ, Maezawa I, Jin LW, Lebrilla CB, Zivkovic AM. PMID: 38882697; PMCID: PMC11177782.
      View in: PubMed   Mentions:
    10. The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathol Commun. 2024 05 24; 12(1):81. Wang HP, Scalco R, Saito N, Beckett L, Nguyen ML, Huie EZ, Honig LS, DeCarli C, Rissman RA, Teich AF, Mungas DM, Jin LW, Dugger BN. PMID: 38790074; PMCID: PMC11127432.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Profiling Intact Glycosphingolipids with Automated Structural Annotation and Quantitation from Human Samples with Nanoflow Liquid Chromatography Mass Spectrometry. Anal Chem. 2024 04 16; 96(15):5951-5959. Schindler RL, Oloumi A, Tena J, Alvarez MRS, Liu Y, Grijaldo S, Barboza M, Jin LW, Zivkovic AM, Lebrilla CB. PMID: 38563595; PMCID: PMC11024888.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Effects of Sex and Western Diet on Spatial Lipidomic Profiles for the Hippocampus, Cortex, and Corpus Callosum in Mice Using MALDI MSI. J Am Soc Mass Spectrom. 2024 Nov 06; 35(11):2554-2563. Shafer CC, Di Lucente J, Mendiola UR, Maezawa I, Jin LW, Neumann EK. PMID: 38456419; PMCID: PMC11544704.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    13. Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes. Commun Biol. 2024 02 16; 7(1):195. Di Lucente J, Persico G, Zhou Z, Jin LW, Ramsey JJ, Rutkowsky JM, Montgomery CM, Tomilov A, Kim K, Giorgio M, Maezawa I, Cortopassi GA. PMID: 38366025; PMCID: PMC10873348.
      View in: PubMed   Mentions: 4  Translation:HumansAnimals
    14. Multi-omics Characterization of Epigenetic and Genetic Risk of Alzheimer Disease in Autopsied Brains from two Ethnic Groups. medRxiv. 2024 Feb 14. Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN. PMID: 38405911; PMCID: PMC10889011.
      View in: PubMed   Mentions:
    15. Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration. bioRxiv. 2024 Jan 22. Panwar A, Rentsendorj A, Jhun M, Cohen RM, Cordner R, Gull N, Pechnick RN, Duvall G, Mardiros A, Golchian D, Schubloom H, Jin LW, Van Dam D, Vermeiren Y, De Reu H, De Deyn PP, Raskatov JA, Black KL, Irvin DK, Williams BA, Wheeler CJ. PMID: 38328072; PMCID: PMC10849535.
      View in: PubMed   Mentions:
    16. Galectin-3 aggravates microglial activation and tau transmission in tauopathy. J Clin Invest. 2024 Jan 16; 134(2). Siew JJ, Chen HM, Chiu FL, Lee CW, Chang YM, Chen HL, Nguyen TNA, Liao HT, Liu M, Hagar HT, Sun YC, Lai HL, Kuo MH, Blum D, Buée L, Jin LW, Chen SY, Ko TM, Huang JR, Kuo HC, Liu FT, Chern Y. PMID: 37988169; PMCID: PMC10786694.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. The ketone body β-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-β oligomer-induced inflammation in human microglia. FASEB J. 2023 11; 37(11):e23261. Jin LW, Di Lucente J, Ruiz Mendiola U, Suthprasertporn N, Tomilov A, Cortopassi G, Kim K, Ramsey JJ, Maezawa I. PMID: 37878335.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    18. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, et al. PMID: 37461624; PMCID: PMC10350126.
      View in: PubMed   Mentions: 2  
    19. The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathol Commun. 2023 06 29; 11(1):105. Scalco R, Saito N, Beckett L, Nguyen ML, Huie E, Wang HP, Flaherty DA, Honig LS, DeCarli C, Rissman RA, Teich AF, Jin LW, Dugger BN. PMID: 37386610; PMCID: PMC10311731.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Cholesterol, Amyloid Beta, Fructose, and LPS Influence ROS and ATP Concentrations and the Phagocytic Capacity of HMC3 Human Microglia Cell Line. Int J Mol Sci. 2023 Jun 20; 24(12). Muñoz Herrera OM, Hong BV, Ruiz Mendiola U, Maezawa I, Jin LW, Lebrilla CB, Harvey DJ, Zivkovic AM. PMID: 37373543; PMCID: PMC10299308.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    21. Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer's disease. Sci Rep. 2023 05 15; 13(1):7816. Tang X, Tena J, Di Lucente J, Maezawa I, Harvey DJ, Jin LW, Lebrilla CB, Zivkovic AM. PMID: 37188790; PMCID: PMC10185676.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. Transthyretin attenuates TDP-43 proteinopathy by autophagy activation via ATF4 in FTLD-TDP. Brain. 2023 05 02; 146(5):2089-2106. Chu YP, Jin LW, Wang LC, Ho PC, Wei WY, Tsai KJ. PMID: 36355566; PMCID: PMC10411944.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. In vivo characterization of the human glioblastoma infiltrative edge with label-free intraoperative fluorescence lifetime imaging. Biomed Opt Express. 2023 May 01; 14(5):2196-2208. Alfonso-Garcia A, Anbunesan SN, Bec J, Lee HS, Jin LW, Bloch O, Marcu L. PMID: 37206147; PMCID: PMC10191664.
      View in: PubMed   Mentions: 2  
    24. Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers. Stroke. 2023 05; 54(5):1227-1235. Sapkota S, Erickson K, Fletcher E, Tomaszewski Farias SE, Jin LW, DeCarli C, Alzheimer’s Disease Neuroimaging Initiative*. PMID: 37021572; PMCID: PMC10121244.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer's Disease. Aging Dis. 2023 Apr 01; 14(2):515-528. Jiang CS, Rana T, Jin LW, Farr SA, Morley JE, Qin H, Liu G, Liu RM. PMID: 37008063; PMCID: PMC10017160.
      View in: PubMed   Mentions: 8     Fields:    
    26. H3G34-mutant diffuse hemispheric glioma with osseous metastases: a case report and literature review. CNS Oncol. 2023 06 01; 12(2):CNS95. Yu N, Lee HS, Raslan OA, Jin LW, Aboud O. PMID: 36919796; PMCID: PMC10171036.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides. J Neuropathol Exp Neurol. 2023 02 21; 82(3):212-220. Oliveira LC, Lai Z, Harvey D, Nzenkue K, Jin LW, Decarli C, Chuah CN, Dugger BN. PMID: 36692190; PMCID: PMC9941825.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer's disease (AD) neuropathology: A hypothesis and review. Front Aging Neurosci. 2023; 15:1096206. Sharp FR, DeCarli CS, Jin LW, Zhan X. PMID: 36845656; PMCID: PMC9950279.
      View in: PubMed   Mentions: 9  
    29. The role of FUT8-catalyzed core fucosylation in Alzheimer's amyloid-β oligomer-induced activation of human microglia. Glia. 2023 05; 71(5):1346-1359. Jin LW, di Lucente J, Ruiz Mendiola U, Tang X, Zivkovic AM, Lebrilla CB, Maezawa I. PMID: 36692036; PMCID: PMC11021125.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    30. Mechanical Cues for Triggering and Regulating Cellular Movement Selectively at the Single-Cell Level. J Phys Chem B. 2023 02 02; 127(4):866-873. Ogorodnik E, Karsai A, Liu YX, Di Lucente J, Huang Y, Keel T, Haudenschild DR, Jin LW, Liu GY. PMID: 36652348.
      View in: PubMed   Mentions:    Fields:    
    31. Intraoperative detection of IDH-mutant glioma using fluorescence lifetime imaging. J Biophotonics. 2023 04; 16(4):e202200291. Noble Anbunesan S, Alfonso-Garcia A, Zhou X, Bec J, Lee HS, Jin LW, Bloch O, Marcu L. PMID: 36510639; PMCID: PMC10522274.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Regio-Specific N-Glycome and N-Glycoproteome Map of the Elderly Human Brain With and Without Alzheimer's Disease. Mol Cell Proteomics. 2022 11; 21(11):100427. Tena J, Maezawa I, Barboza M, Wong M, Zhu C, Alvarez MR, Jin LW, Zivkovic AM, Lebrilla CB. PMID: 36252735; PMCID: PMC9674923.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    33. Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimers Dement (Amst). 2022; 14(1):e12349. Sapkota S, Erickson K, Harvey D, Tomaszewski-Farias SE, Olichney JM, Johnson DK, Dugger BN, Mungas DM, Fletcher E, Maillard P, Seshadri S, Satizabal CL, Kautz T, Parent D, Tracy RP, Maezawa I, Jin LW, DeCarli C. PMID: 36092690; PMCID: PMC9434579.
      View in: PubMed   Mentions: 10  
    34. High-Density Lipoprotein Changes in Alzheimer's Disease Are APOE Genotype-Specific. Biomedicines. 2022 Jun 24; 10(7). Hong BV, Zheng J, Agus JK, Tang X, Lebrilla CB, Jin LW, Maezawa I, Erickson K, Harvey DJ, DeCarli CS, Mungas DM, Olichney JM, Farias ST, Zivkovic AM. PMID: 35884800; PMCID: PMC9312991.
      View in: PubMed   Mentions: 11  
    35. Glycosylation alterations in serum of Alzheimer's disease patients show widespread changes in N-glycosylation of proteins related to immune function, inflammation, and lipoprotein metabolism. Alzheimers Dement (Amst). 2022; 14(1):e12309. Tena J, Tang X, Zhou Q, Harvey D, Barajas-Mendoza M, Jin LW, Maezawa I, Zivkovic AM, Lebrilla CB. PMID: 35496372; PMCID: PMC9043904.
      View in: PubMed   Mentions: 11  
    36. First in patient assessment of brain tumor infiltrative margins using simultaneous time-resolved measurements of 5-ALA-induced PpIX fluorescence and tissue autofluorescence. J Biomed Opt. 2022 02; 27(2). Alfonso-García A, Zhou X, Bec J, Anbunesan SN, Fereidouni F, Jin LW, Lee HS, Bloch O, Marcu L. PMID: 35112514; PMCID: PMC8809358.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    37. Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline. Cells. 2022 02 01; 11(3). Jena PK, Setayesh T, Sheng L, Di Lucente J, Jin LW, Wan YY. PMID: 35159313; PMCID: PMC8834507.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    38. Lipopolysaccharide, Identified Using an Antibody and by PAS Staining, Is Associated With Corpora amylacea and White Matter Injury in Alzheimer's Disease and Aging Brain. Front Aging Neurosci. 2021; 13:705594. Zhan X, Hakoupian M, Jin LW, Sharp FR. PMID: 34899263; PMCID: PMC8652352.
      View in: PubMed   Mentions: 7  
    39. 1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain. Light Sci Appl. 2021 Jul 14; 10(1):145. Zhu J, Freitas HR, Maezawa I, Jin LW, Srinivasan VJ. PMID: 34262015; PMCID: PMC8280201.
      View in: PubMed   Mentions: 13  
    40. Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy. Acta Neuropathol Commun. 2021 06 22; 9(1):112. Chang CP, Chang YG, Chuang PY, Nguyen TNA, Wu KC, Chou FY, Cheng SJ, Chen HM, Jin LW, Carvalho K, Huin V, Buée L, Liao YF, Lin CJ, Blum D, Chern Y. PMID: 34158119; PMCID: PMC8220833.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    41. Lipidomic Analysis of Postmortem Prefrontal Cortex Phospholipids Reveals Changes in Choline Plasmalogen Containing Docosahexaenoic Acid and Stearic Acid Between Cases With and Without Alzheimer's Disease. Neuromolecular Med. 2021 03; 23(1):161-175. Otoki Y, Kato S, Nakagawa K, Harvey DJ, Jin LW, Dugger BN, Taha AY. PMID: 33475971.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    42. TDP-43 proteinopathy impairs mRNP granule mediated postsynaptic translation and mRNA metabolism. Theranostics. 2021; 11(1):330-345. Wong CE, Jin LW, Chu YP, Wei WY, Ho PC, Tsai KJ. PMID: 33391478; PMCID: PMC7681104.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    43. TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer's disease. Nat Commun. 2020 11 23; 11(1):5950. Shih YH, Tu LH, Chang TY, Ganesan K, Chang WW, Chang PS, Fang YS, Lin YT, Jin LW, Chen YR. PMID: 33230138; PMCID: PMC7683652.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    44. Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function. Biomark Res. 2020 Nov 06; 8(1):59. Jena PK, Sheng L, Nguyen M, Di Lucente J, Hu Y, Li Y, Maezawa I, Jin LW, Wan YY. PMID: 33292701; PMCID: PMC7648397.
      View in: PubMed   Mentions: 22  
    45. Metabolic flux analysis of the neural cell glycocalyx reveals differential utilization of monosaccharides. Glycobiology. 2020 10 21; 30(11):859-871. Wong M, Xu G, Barboza M, Maezawa I, Jin LW, Zivkovic A, Lebrilla CB. PMID: 32337579; PMCID: PMC7581652.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    46. Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor. Acta Neuropathol Commun. 2020 08 28; 8(1):151. Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, Cooney T, Cham E, Jin LW, Khatib Z, Maher O, Chamyan G, Brathwaite C, Bannykh S, Mueller S, Kline CN, Banerjee A, Reddy A, Taylor JW, Clarke JL, Oberheim Bush NA, Butowski N, Gupta N, Auguste KI, Sun PP, Roland JL, Raffel C, Aghi MK, Theodosopoulos P, Chang E, Hervey-Jumper S, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Chang S, Berger MS, Perry A, Solomon DA. PMID: 32859279; PMCID: PMC7456392.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    47. Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease. J Clin Invest. 2020 08 03; 130(8):4195-4212. Sarkar S, Nguyen HM, Malovic E, Luo J, Langley M, Palanisamy BN, Singh N, Manne S, Neal M, Gabrielle M, Abdalla A, Anantharam P, Rokad D, Panicker N, Singh V, Ay M, Charli A, Harischandra D, Jin LW, Jin H, Rangaraju S, Anantharam V, Wulff H, Kanthasamy AG. PMID: 32597830; PMCID: PMC7410064.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    48. Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia. Glia. 2020 11; 68(11):2377-2394. Nguyen HM, di Lucente J, Chen YJ, Cui Y, Ibrahim RH, Pennington MW, Jin LW, Maezawa I, Wulff H. PMID: 32525239; PMCID: PMC7540709.
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    49. HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP-43 proteinopathies. EMBO Mol Med. 2020 06 08; 12(6):e10622. Wu CC, Jin LW, Wang IF, Wei WY, Ho PC, Liu YC, Tsai KJ. PMID: 32449313; PMCID: PMC7278561.
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    50. Intellectual and Developmental Disabilities Research Centers: A Multidisciplinary Approach to Understand the Pathogenesis of Methyl-CpG Binding Protein 2-related Disorders. Neuroscience. 2020 10 01; 445:190-206. Fagiolini M, Patrizi A, LeBlanc J, Jin LW, Maezawa I, Sinnett S, Gray SJ, Molholm S, Foxe JJ, Johnston MV, Naidu S, Blue M, Hossain A, Kadam S, Zhao X, Chang Q, Zhou Z, Zoghbi H. PMID: 32360592; PMCID: PMC8025698.
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    51. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathol. 2020 06; 139(6):1071-1088. Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, Metrock LK, Jin LW, Antony R, Alashari M, Cheshier S, Whipple NS, Bruggers C, Raffel C, Gupta N, Kline CN, Reddy A, Banerjee A, Hall MD, Mehta MP, Khatib Z, Maher OM, Brathwaite C, Pekmezci M, Phillips JJ, Bollen AW, Tihan T, Lucas JT, Broniscer A, Berger MS, Perry A, Orr BA, Solomon DA. PMID: 32303840; PMCID: PMC7792550.
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    52. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, et al. PMID: 31417202; PMCID: PMC7265117.
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    53. Interpretable classification of Alzheimer's disease pathologies with a convolutional neural network pipeline. Nat Commun. 2019 05 15; 10(1):2173. Tang Z, Chuang KV, DeCarli C, Jin LW, Beckett L, Keiser MJ, Dugger BN. PMID: 31092819; PMCID: PMC6520374.
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    54. Corrigendum to "Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease" [EBioMedicine 2 (2015) 294-305]. EBioMedicine. 2019 04; 42:532. Zhang L, Zhang S, Maezawa I, Trushin S, Minhas P, Pinto M, Jin LW, Prasain K, Nguyen TDT, Yamazaki Y, Kanekiyo T, Bu G, Gateno B, Chang KO, Nath KA, Nemutlu E, Dzeja P, Pang YP, Hua DH, Trushina E. PMID: 30956174; PMCID: PMC6491797.
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    55. Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. Ann Clin Transl Neurol. 2019 Apr; 6(4):723-738. Jin LW, Lucente JD, Nguyen HM, Singh V, Singh L, Chavez M, Bushong T, Wulff H, Maezawa I. PMID: 31019997; PMCID: PMC6469250.
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    56. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, et al. PMID: 30820047; PMCID: PMC6463297.
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    57. Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer's Disease Center. J Alzheimers Dis. 2019; 68(1):145-158. Filshtein TJ, Dugger BN, Jin LW, Olichney JM, Farias ST, Carvajal-Carmona L, Lott P, Mungas D, Reed B, Beckett LA, DeCarli C. PMID: 30775996; PMCID: PMC7286069.
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    58. Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology. Alzheimers Dement. 2019 02; 15(2):205-216. La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD. PMID: 30347188; PMCID: PMC6368897.
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    59. A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta. Molecules. 2018 Aug 12; 23(8). Hilt S, Altman R, Kálai T, Maezawa I, Gong Q, Wachsmann-Hogiu S, Jin LW, Voss JC. PMID: 30103547; PMCID: PMC6222334.
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    60. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. JAMA Neurol. 2018 08 01; 75(8):989-998. Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL, Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative. PMID: 29801024; PMCID: PMC6142927.
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    61. The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo. Glia. 2018 09; 66(9):1881-1895. Di Lucente J, Nguyen HM, Wulff H, Jin LW, Maezawa I. PMID: 30043400; PMCID: PMC6185766.
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    62. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872. Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. PMID: 29967939; PMCID: PMC6280657.
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    63. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. Brain. 2018 02 01; 141(2):596-612. Maezawa I, Nguyen HM, Di Lucente J, Jenkins DP, Singh V, Hilt S, Kim K, Rangaraju S, Levey AI, Wulff H, Jin LW. PMID: 29272333; PMCID: PMC5837198.
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    64. Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity. FASEB J. 2018 05; 32(5):2866-2877. Jena PK, Sheng L, Di Lucente J, Jin LW, Maezawa I, Wan YY. PMID: 29401580; PMCID: PMC5901391.
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    65. Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke. Ann Clin Transl Neurol. 2018 02; 5(2):147-161. Chen YJ, Nguyen HM, Maezawa I, Jin LW, Wulff H. PMID: 29468176; PMCID: PMC5817832.
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    66. Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. Neurobiol Dis. 2018 Jan; 109(Pt A):25-32. Chen CY, Di Lucente J, Lin YC, Lien CC, Rogawski MA, Maezawa I, Jin LW. PMID: 28927958; PMCID: PMC5696074.
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    67. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, et al. PMID: 28714976; PMCID: PMC5669039.
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    68. ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3129-E3138. Wang BJ, Her GM, Hu MK, Chen YW, Tung YT, Wu PY, Hsu WM, Lee H, Jin LW, Hwang SL, Chen RP, Huang CJ, Liao YF. PMID: 28351972; PMCID: PMC5393216.
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    69. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738. Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Alzheimer's Disease Genetics Consortium, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. PMID: 28183528; PMCID: PMC5496797.
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    70. A Metal-Free Method for Producing MRI Contrast at Amyloid-β. J Alzheimers Dis. 2017; 55(4):1667-1681. Hilt S, Tang T, Walton JH, Budamagunta M, Maezawa I, Kálai T, Hideg K, Singh V, Wulff H, Gong Q, Jin LW, Louie A, Voss JC. PMID: 27911291; PMCID: PMC5718836.
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    71. The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule. J Alzheimers Dis. 2017; 58(2):559-574. Maezawa I, Zou B, Di Lucente J, Cao WS, Pascual C, Weerasekara S, Zhang M, Xie XS, Hua DH, Jin LW. PMID: 28482635; PMCID: PMC5438482.
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    72. Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1035-1041. Liu CY, Ohki Y, Tomita T, Osawa S, Reed BR, Jagust W, Van Berlo V, Jin LW, Chui HC, Coppola G, Ringman JM. PMID: 28550247.
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    73. Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort. Neuroimage Clin. 2017; 13:130-137. Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil JP, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 27981028; PMCID: PMC5144753.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    74. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016 Nov 29; 87(22):2324-2332. Zhan X, Stamova B, Jin LW, DeCarli C, Phinney B, Sharp FR. PMID: 27784770; PMCID: PMC5135029.
      View in: PubMed   Mentions: 234     Fields:    Translation:HumansCells
    75. Differential Kv1.3, KCa3.1, and Kir2.1 expression in "classically" and "alternatively" activated microglia. Glia. 2017 01; 65(1):106-121. Nguyen HM, Grössinger EM, Horiuchi M, Davis KW, Jin LW, Maezawa I, Wulff H. PMID: 27696527; PMCID: PMC5113690.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    76. Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation. Acta Neuropathol. 2016 11; 132(5):757-760. Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Jin LW, Bastian BC, Bollen AW, Perry A, Nicolaides T, Solomon DA, Shieh JT. PMID: 27624885; PMCID: PMC5074852.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    77. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging. 2016 May; 41:200.e13-200.e20. Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK, Alzheimer's Disease Genetics Consortium (ADGC). PMID: 27036079; PMCID: PMC4948179.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    78. Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One. 2016; 11(2):e0148717. Karch CM, Ezerskiy LA, Bertelsen S, Alzheimer’s Disease Genetics Consortium (ADGC), Goate AM. PMID: 26919393; PMCID: PMC4769299.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    79. CX3CR1 ablation ameliorates motor and respiratory dysfunctions and improves survival of a Rett syndrome mouse model. Brain Behav Immun. 2017 Feb; 60:106-116. Horiuchi M, Smith L, Maezawa I, Jin LW. PMID: 26883520; PMCID: PMC5531048.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    80. Dendrites in Autism Spectrum Disorders. . 2016 Jan 1; 525-543. Martínez-Cerdeño MV, Maezawa MI, Jin JL. .
      View in: Publisher Site   Mentions:
    81. The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke. J Cereb Blood Flow Metab. 2016 12; 36(12):2146-2161. Chen YJ, Nguyen HM, Maezawa I, Grössinger EM, Garing AL, Köhler R, Jin LW, Wulff H. PMID: 26661208; PMCID: PMC5363659.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    82. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23. Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith PA, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, St George-Hyslop P, Mayeux R, Rogaeva E, Alzheimer’s Disease Genetics Consortium. PMID: 26366463; PMCID: PMC4641052.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    83. Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure. Biochim Biophys Acta. 2015 Dec; 1854(12):1860-1870. Altman R, Ly S, Hilt S, Petrlova J, Maezawa I, Kálai T, Hideg K, Jin LW, Laurence TA, Voss JC. PMID: 26374940; PMCID: PMC4631661.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    84. Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. Ann Neurol. 2015 Aug; 78(2):211-21. Kao PF, Chen YR, Liu XB, DeCarli C, Seeley WW, Jin LW. PMID: 25921485; PMCID: PMC4822421.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    85. Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Med. 2015 Jun; 12(6):e1001841; discussion e1001841. Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Alzheimer’s Disease Genetics Consortium, GERAD1 Consortium, EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. PMID: 26079503; PMCID: PMC4469461.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    86. Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. Alzheimers Dement. 2015 Dec; 11(12):1439-1451. Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM, Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators, Alzheimer's Disease Genetics Consortium. PMID: 26079416; PMCID: PMC4676945.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    87. Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015 Jul; 138(Pt 7):2020-33. Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin LW, Huang EJ, Grinberg LT, DeCarli C, Seeley WW, Jagust W. PMID: 25953778; PMCID: PMC4806716.
      View in: PubMed   Mentions: 226     Fields:    Translation:Humans
    88. Intradural extramedullary capillary hemangioma of the cauda equina: Case report and literature review. Surg Neurol Int. 2015; 6(Suppl 3):S127-31. Liu JJ, Lee DJ, Jin LW, Kim KD. PMID: 25949855; PMCID: PMC4408617.
      View in: PubMed   Mentions: 7  
    89. Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease. EBioMedicine. 2015 Apr 01; 2(4):294-305. Zhang L, Zhang S, Maezawa I, Trushin S, Minhas P, Pinto M, Jin LW, Prasain K, Nguyen TD, Yamazaki Y, Kanekiyo T, Bu G, Gateno B, Chang KO, Nath KA, Nemutlu E, Dzeja P, Pang YP, Hua DH, Trushina E. PMID: 26086035; PMCID: PMC4465115.
      View in: PubMed   Mentions: 59     Fields:    
    90. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17. Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L, IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. PMID: 25778476; PMCID: PMC4573764.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCells
    91. Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity. J Neurosci. 2015 Feb 11; 35(6):2516-29. Jin LW, Horiuchi M, Wulff H, Liu XB, Cortopassi GA, Erickson JD, Maezawa I. PMID: 25673846; PMCID: PMC4323531.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    92. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25531812; PMCID: PMC4324097.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    93. Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(4):1213-29. Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp FR. PMID: 25697841; PMCID: PMC4422390.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    94. Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. J Alzheimers Dis. 2015; 46(2):507-23. Zhan X, Cox C, Ander BP, Liu D, Stamova B, Jin LW, Jickling GC, Sharp FR. PMID: 25790832; PMCID: PMC4878315.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    95. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. J Alzheimers Dis. 2015; 44(3):797-808. Rangaraju S, Gearing M, Jin LW, Levey A. PMID: 25362031; PMCID: PMC4402159.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    96. Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity. J Alzheimers Dis. 2015; 48(3):731-43. Hong HS, Maezawa I, Petrlova J, Zhao XY, C Voss J, Jin LW. PMID: 26402097; PMCID: PMC5533101.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    97. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Alzheimer Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25199842; PMCID: PMC4314944.
      View in: PubMed   Mentions: 104     Fields:    Translation:Humans
    98. Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients. Nat Commun. 2014 Sep 12; 5:4824. Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR. PMID: 25215604.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    99. A case of familial ALS due to multi-system proteinopathy 1 and Huntington disease. Amyotroph Lateral Scler Frontotemporal Degener. 2015 Mar; 16(1-2):124-6. Oskarsson B, Wheelock V, Benatar M, Taylor JP, Joyce N, Chesak D, Jin LW. PMID: 25205077; PMCID: PMC4664522.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    100. Syntheses of 3-[(Alkylamino)methylene]-6-methylpyridine-2,4(1H,3H)-diones, 3-Substituted 7-Methyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione Fluorescence Probes, and Tetrahydro-1H,9H-2,10-dioxa-9-azaanthracen-1-ones. Synthesis (Stuttg). 2014 Aug; 46(16):2179-2190. Prior AM, Gunaratna MJ, Kikuchi D, Desper J, Kim Y, Chang KO, Maezawa I, Jin LW, Hua DH. PMID: 25177061; PMCID: PMC4146570.
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    101. Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):226-33. Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp FR. PMID: 24731980; PMCID: PMC4139468.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    102. Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3β of substituted quinolines. Bioorg Med Chem Lett. 2014 Aug 01; 24(15):3392-7. Lu J, Maezawa I, Weerasekara S, Erenler R, Nguyen TD, Nguyen J, Swisher LZ, Li J, Jin LW, Ranjan A, Srivastava SK, Hua DH. PMID: 24951331; PMCID: PMC4110911.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    103. Pathology of inherited manganese transporter deficiency. Ann Neurol. 2014 Apr; 75(4):608-12. Lechpammer M, Clegg MS, Muzar Z, Huebner PA, Jin LW, Gospe SM. PMID: 24599576.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    104. Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors. Eur J Med Chem. 2014 Apr 22; 77:343-50. Kálai T, Altman R, Maezawa I, Balog M, Morisseau C, Petrlova J, Hammock BD, Jin LW, Trudell JR, Voss JC, Hideg K. PMID: 24657571; PMCID: PMC4065883.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    105. Myelin injury and degraded myelin vesicles in Alzheimer's disease. Curr Alzheimer Res. 2014 Mar; 11(3):232-8. Zhan X, Jickling GC, Ander BP, Liu D, Stamova B, Cox C, Jin LW, DeCarli C, Sharp FR. PMID: 24484278; PMCID: PMC4066812.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    106. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Mar; 127(3):407-18. Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, DeCarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White CL, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin AS. PMID: 24442578; PMCID: PMC4003885.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    107. Chromosome 19p in Alzheimer's disease: when genome meets transcriptome. J Alzheimers Dis. 2014; 38(2):245-50. Wang J, Feng X, Bai Z, Jin LW, Duan Y, Lei H. PMID: 23963291.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    108. Solitary plexiform neurofibroma of the forehead: A rare and unusual presentation. International Journal of Pediatric Otorhinolaryngology Case Reports. 2014 Jan 1; 9(1):15-17. Rong RA, Ledgerwood LL, Jin JL, Tollefson TT. .
      View in: Publisher Site   Mentions:
    109. Neurodevelopmental and Neuropsychiatric Disorders. . 2014 Jan 1; 345-372. Monji MA, Maezawa MI, Mizoguchi MY, Kato KT, Jin JL. .
      View in: Publisher Site   Mentions:
    110. Amylin deposition in the brain: A second amyloid in Alzheimer disease? Ann Neurol. 2013 Oct; 74(4):517-26. Jackson K, Barisone GA, Diaz E, Jin LW, DeCarli C, Despa F. PMID: 23794448; PMCID: PMC3818462.
      View in: PubMed   Mentions: 182     Fields:    Translation:Humans
    111. MeCP2 modulates gene expression pathways in astrocytes. Mol Autism. 2013 Jan 25; 4(1):3. Yasui DH, Xu H, Dunaway KW, Lasalle JM, Jin LW, Maezawa I. PMID: 23351786; PMCID: PMC3561260.
      View in: PubMed   Mentions: 57     Fields:    
    112. Characteristic transformation of blood transcriptome in Alzheimer's disease. J Alzheimers Dis. 2013; 35(2):373-86. Han G, Wang J, Zeng F, Feng X, Yu J, Cao HY, Yi X, Zhou H, Jin LW, Duan Y, Wang YJ, Lei H. PMID: 23411692.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    113. Microglia in Alzheimer's disease. Int J Alzheimers Dis. 2012; 2012:598371. Jin LW. PMID: 23251825; PMCID: PMC3515896.
      View in: PubMed   Mentions: 3  
    114. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54. Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alzheimer's Disease Genetics Consortium, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. PMID: 23143602; PMCID: PMC3510344.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    115. Inhibition of Acyl-CoA: cholesterol acyltransferase (ACAT), overexpression of cholesterol transporter gene, and protection of amyloid β (Aβ) oligomers-induced neuronal cell death by tricyclic pyrone molecules. J Med Chem. 2012 Oct 25; 55(20):8969-73. Pokhrel L, Maezawa I, Nguyen TD, Chang KO, Jin LW, Hua DH. PMID: 23025824; PMCID: PMC3486708.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    116. Muscle biopsy evaluation in neuromuscular disorders. Phys Med Rehabil Clin N Am. 2012 Aug; 23(3):609-31. Joyce NC, Oskarsson B, Jin LW. PMID: 22938878; PMCID: PMC4590778.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    117. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N, Alzheimer's Disease Genetics Consortium (ADGC), Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL. PMID: 22722634; PMCID: PMC3398432.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    118. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Alzheimer's Disease Genetics Consortium, Ross OA, Rademakers R, Schellenberg GD, Miller BL, Mandelkow E, Geschwind DH. PMID: 22556362; PMCID: PMC3392107.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    119. Does microglial dysfunction play a role in autism and Rett syndrome? Neuron Glia Biol. 2011 Feb; 7(1):85-97. Maezawa I, Calafiore M, Wulff H, Jin LW. PMID: 22717189; PMCID: PMC4976478.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    120. The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide. PLoS One. 2012; 7(4):e35443. Petrlova J, Kálai T, Maezawa I, Altman R, Harishchandra G, Hong HS, Bricarello DA, Parikh AN, Lorigan GA, Jin LW, Hideg K, Voss JC. PMID: 22558151; PMCID: PMC3340382.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    121. Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS. Genes Brain Behav. 2012 Jul; 11(5):577-85. Tassone F, Greco CM, Hunsaker MR, Seritan AL, Berman RF, Gane LW, Jacquemont S, Basuta K, Jin LW, Hagerman PJ, Hagerman RJ. PMID: 22463693; PMCID: PMC3965773.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    122. Clinical features, with video documentation, of the original familial lewy body parkinsonism caused by α-synuclein triplication (Iowa kindred). Mov Disord. 2011 Sep; 26(11):2134-6. Gwinn K, Devine MJ, Jin LW, Johnson J, Bird T, Muenter M, Waters C, Adler CH, Caselli R, Houlden H, Lopez G, Singleton A, Hardy J, Singleton A. PMID: 21656851; PMCID: PMC3170657.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    123. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. PMID: 21460841; PMCID: PMC3090745.
      View in: PubMed   Mentions: 1089     Fields:    Translation:Humans
    124. Alzheimer's disease drug candidates stabilize A-β protein native structure by interacting with the hydrophobic core. Biophys J. 2011 Feb 16; 100(4):1076-82. Li J, Liu R, Lam KS, Jin LW, Duan Y. PMID: 21320453; PMCID: PMC3037571.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    125. Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol Autism. 2011 Feb 08; 2(1):2. Greco CM, Navarro CS, Hunsaker MR, Maezawa I, Shuler JF, Tassone F, Delany M, Au JW, Berman RF, Jin LW, Schumann C, Hagerman PJ, Hagerman RJ. PMID: 21303513; PMCID: PMC3045897.
      View in: PubMed   Mentions: 41     Fields:    
    126. A differential association of Apolipoprotein E isoforms with the amyloid-β oligomer in solution. Proteins. 2011 Feb; 79(2):402-16. Petrlova J, Hong HS, Bricarello DA, Harishchandra G, Lorigan GA, Jin LW, Voss JC. PMID: 21069870; PMCID: PMC3016465.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    127. Amyloid-beta protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity. J Biol Chem. 2011 Feb 04; 286(5):3693-706. Maezawa I, Zimin PI, Wulff H, Jin LW. PMID: 20971854; PMCID: PMC3030372.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    128. Single-cell mechanics provides a sensitive and quantitative means for probing amyloid-beta peptide and neuronal cell interactions. Proc Natl Acad Sci U S A. 2010 Aug 03; 107(31):13872-7. Lulevich V, Zimmer CC, Hong HS, Jin LW, Liu GY. PMID: 20643929; PMCID: PMC2922280.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    129. Amyloid β1-42 oligomer inhibits myelin sheet formation in vitro. Neurobiol Aging. 2012 Mar; 33(3):499-509. Horiuchi M, Maezawa I, Itoh A, Wakayama K, Jin LW, Itoh T, Decarli C. PMID: 20594620; PMCID: PMC3013291.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    130. Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate. J Neurosci. 2010 Apr 14; 30(15):5346-56. Maezawa I, Jin LW. PMID: 20392956; PMCID: PMC5533099.
      View in: PubMed   Mentions: 194     Fields:    Translation:AnimalsCells
    131. Whole-body biodistribution and brain PET imaging with [18F]AV-45, a novel amyloid imaging agent--a pilot study. Nucl Med Biol. 2010 May; 37(4):497-508. Lin KJ, Hsu WC, Hsiao IT, Wey SP, Jin LW, Skovronsky D, Wai YY, Chang HP, Lo CW, Yao CH, Yen TC, Kung MP. PMID: 20447562.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCTClinical Trials
    132. Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci. 2009 Apr 22; 29(16):5051-61. Maezawa I, Swanberg S, Harvey D, LaSalle JM, Jin LW. PMID: 19386901; PMCID: PMC3436907.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansAnimalsCells
    133. Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo. J Neurochem. 2009 Feb; 108(4):1097-1108. Hong HS, Rana S, Barrigan L, Shi A, Zhang Y, Zhou F, Jin LW, Hua DH. PMID: 19141069; PMCID: PMC2748761.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    134. Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death. Bioorg Med Chem Lett. 2009 Feb 01; 19(3):670-4. Rana S, Hong HS, Barrigan L, Jin LW, Hua DH. PMID: 19121940.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    135. Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging. 2010 Oct; 31(10):1690-9. Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu R, Lam KS, Cheng RH, Hua DH, Voss JC, Jin LW. PMID: 19022536; PMCID: PMC2888733.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    136. Congo red and thioflavin-T analogs detect Abeta oligomers. J Neurochem. 2008 Jan; 104(2):457-68. Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. PMID: 17953662.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    137. Mapping the structural transition in an amyloidogenic apolipoprotein A-I. Biochemistry. 2007 Aug 28; 46(34):9693-9. Lagerstedt JO, Cavigiolio G, Roberts LM, Hong HS, Jin LW, Fitzgerald PG, Oda MN, Voss JC. PMID: 17665932; PMCID: PMC3650831.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    138. Radioiodinated aza-diphenylacetylenes as potential SPECT imaging agents for beta-amyloid plaque detection. Bioorg Med Chem Lett. 2007 Jul 01; 17(13):3581-4. Qu W, Kung MP, Hou C, Jin LW, Kung HF. PMID: 17502139; PMCID: PMC1950143.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    139. New diphenylacetylenes as probes for positron emission tomographic imaging of amyloid plaques. J Med Chem. 2007 May 17; 50(10):2415-23. Chandra R, Oya S, Kung MP, Hou C, Jin LW, Kung HF. PMID: 17447752.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    140. Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from alzheimer's disease patients. Magn Reson Med. 2007 Jan; 57(1):172-80. House MJ, St Pierre TG, Kowdley KV, Montine T, Connor J, Beard J, Berger J, Siddaiah N, Shankland E, Jin LW. PMID: 17191232.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    141. Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity. Brain Res. 2007 Jan 26; 1130(1):223-34. Hong HS, Maezawa I, Yao N, Xu B, Diaz-Avalos R, Rana S, Hua DH, Cheng RH, Lam KS, Jin LW. PMID: 17157826; PMCID: PMC1880896.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    142. Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer disease. Arch Neurol. 2006 Aug; 63(8):1165-9. Ramos EM, Lin MT, Larson EB, Maezawa I, Tseng LH, Edwards KL, Schellenberg GD, Hansen JA, Kukull WA, Jin LW. PMID: 16908746.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    143. A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-beta oligomeric complexes. J Neurochem. 2006 Jul; 98(1):57-67. Maezawa I, Hong HS, Wu HC, Battina SK, Rana S, Iwamoto T, Radke GA, Pettersson E, Martin GM, Hua DH, Jin LW. PMID: 16805796.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    144. Fatty acid compositions of red blood cell phospholipids in children with autism. Prostaglandins Leukot Essent Fatty Acids. 2006 Apr; 74(4):215-21. Bu B, Ashwood P, Harvey D, King IB, Water JV, Jin LW. PMID: 16581239.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    145. Polarimetric imaging of amyloid. Micron. 2006; 37(4):324-38. Kaminksy W, Jin LW, Powell S, Maezawa I, Claborn K, Branham C, Kahr B. PMID: 16406217.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    146. Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro. J Neurosci Res. 2005 May 01; 80(3):406-13. Vuletic S, Peskind ER, Marcovina SM, Quinn JF, Cheung MC, Kennedy H, Kaye JA, Jin LW, Albers JJ. PMID: 15795933.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    147. Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity. J Neurochem. 2004 Dec; 91(6):1312-21. Maezawa I, Jin LW, Woltjer RL, Maeda N, Martin GM, Montine TJ, Montine KS. PMID: 15584908.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    148. Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration. Neuron. 2004 Mar 04; 41(5):687-99. Sopher BL, Thomas PS, LaFevre-Bernt MA, Holm IE, Wilke SA, Ware CB, Jin LW, Libby RT, Ellerby LM, La Spada AR. PMID: 15003169.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    149. Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities. Am J Pathol. 2004 Mar; 164(3):975-85. Jin LW, Shie FS, Maezawa I, Vincent I, Bird T. PMID: 14982851; PMCID: PMC1614713.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    150. Isoform-specific knockout of FE65 leads to impaired learning and memory. J Neurosci Res. 2004 Jan 01; 75(1):12-24. Wang B, Hu Q, Hearn MG, Shimizu K, Ware CB, Liggitt DH, Jin LW, Cool BH, Storm DR, Martin GM. PMID: 14689444.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    151. Imaging linear birefringence and dichroism in cerebral amyloid pathologies. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15294-8. Jin LW, Claborn KA, Kurimoto M, Geday MA, Maezawa I, Sohraby F, Estrada M, Kaminksy W, Kahr B. PMID: 14668440; PMCID: PMC307560.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    152. Syntheses and bioactivities of tricyclic pyrones. Tetrahedron. 2003 Jun 1; 59(26):4795-4803. Hua HD, Huang HX, Tamura TM, Chen CY, Woltkamp WM, Jin JL, Perchellet PE, Perchellet PJ, Chiang CP, Namatame NI, Tomoda TH. .
      View in: Publisher Site   Mentions:
    153. Widespread distribution of PLTP in human CNS: evidence for PLTP synthesis by glia and neurons, and increased levels in Alzheimer's disease. J Lipid Res. 2003 Jun; 44(6):1113-23. Vuletic S, Jin LW, Marcovina SM, Peskind ER, Moller T, Albers JJ. PMID: 12671035.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    154. Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice. Neuroreport. 2003 Jan 20; 14(1):123-9. Shie FS, LeBoeuf RC, Jin LW, LeBoeur RC. PMID: 12544843.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    155. Characterization of radioiodinated ligand binding to amyloid beta plaques. J Mol Neurosci. 2003; 20(3):249-54. Kung MP, Zhuang ZP, Hou C, Jin LW, Kung HF. PMID: 14501004.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    156. Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. Am J Pathol. 2003 Jan; 162(1):313-9. Cook DG, Leverenz JB, McMillan PJ, Kulstad JJ, Ericksen S, Roth RA, Schellenberg GD, Jin LW, Kovacina KS, Craft S. PMID: 12507914; PMCID: PMC1851126.
      View in: PubMed   Mentions: 115     Fields:    Translation:Humans
    157. Genetic modulation of tau phosphorylation in the mouse. J Neurosci. 2003 Jan 01; 23(1):187-92. Brich J, Shie FS, Howell BW, Li R, Tus K, Wakeland EK, Jin LW, Mumby M, Churchill G, Herz J, Cooper JA. PMID: 12514215; PMCID: PMC6742161.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    158. Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles. Neurobiol Dis. 2002 Nov; 11(2):285-97. Bu B, Klunemann H, Suzuki K, Li J, Bird T, Jin LW, Vincent I. PMID: 12505421.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    159. Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity. Pathol Int. 2002 Sep; 52(9):551-4. Maezawa I, Wang B, Hu Q, Martin GM, Jin LW, Oshima J. PMID: 12406183.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    160. Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):57-61. Jin LW, Hua DH, Shie FS, Maezawa I, Sopher B, Martin GM. PMID: 12212794.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    161. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat Med. 2002 Jun; 8(6):600-6. Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. PMID: 12042811.
      View in: PubMed   Mentions: 264     Fields:    Translation:HumansCells
    162. Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport. 2002 Mar 25; 13(4):455-9. Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC. PMID: 11930160.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    163. Hyperphosphorylation of RNA polymerase II and reduced neuronal RNA levels precede neurofibrillary tangles in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Dec; 60(12):1219-32. Husseman JW, Hallows JL, Bregman DB, Leverenz JB, Nochlin D, Jin LW, Vincent I. PMID: 11764094.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    164. Constitutive Wee1 activity in adult brain neurons with M phase-type alterations in Alzheimer neurodegeneration. J Alzheimers Dis. 2001 Apr; 3(2):195-207. Tomashevski A, Husseman J, Jin LW, Nochlin D, Vincent I. PMID: 12214061.
      View in: PubMed   Mentions: 17     Fields:    
    165. Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease. Neuroscience. 2001; 105(3):639-50. Vincent I, Bu B, Hudson K, Husseman J, Nochlin D, Jin L. PMID: 11516829.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    166. The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease. Am J Pathol. 2000 Dec; 157(6):1983-90. Ding XL, Husseman J, Tomashevski A, Nochlin D, Jin LW, Vincent I. PMID: 11106571; PMCID: PMC1885767.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    167. Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions. J Neurosci Res. 2000 Apr 01; 60(1):73-86. Hu Q, Jin LW, Starbuck MY, Martin GM. PMID: 10723070.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    168. Alternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markers. J Neurosci Res. 1999 Dec 01; 58(5):632-40. Hu Q, Hearn MG, Jin LW, Bressler SL, Martin GM. PMID: 10561691.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    169. Transgenic mice over-expressing the C-99 fragment of betaPP with an alpha-secretase site mutation develop a myopathy similar to human inclusion body myositis. Am J Pathol. 1998 Dec; 153(6):1679-86. Jin LW, Hearn MG, Ogburn CE, Dang N, Nochlin D, Ladiges WC, Martin GM. PMID: 9846957; PMCID: PMC1866341.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    170. Neurofibrillary tangle-associated alteration of stathmin in Alzheimer's disease. Neurobiol Aging. 1996 May-Jun; 17(3):331-41. Jin LW, Masliah E, Iimoto D, Deteresa R, Mallory M, Sundsmo M, Mori N, Sobel A, Saitoh T. PMID: 8725893.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    171. Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy. Drugs Aging. 1995 Feb; 6(2):136-49. Jin LW, Saitoh T. PMID: 7711360.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    172. Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J Neurosci. 1994 Sep; 14(9):5461-70. Jin LW, Ninomiya H, Roch JM, Schubert D, Masliah E, Otero DA, Saitoh T. PMID: 8083748; PMCID: PMC6577069.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    173. Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity. J Neurochem. 1994 Aug; 63(2):495-500. Ninomiya H, Roch JM, Jin LW, Saitoh T. PMID: 7913487.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    174. Biologically active domain of the secreted form of the amyloid beta/A4 protein precursor. Ann N Y Acad Sci. 1993 Sep 24; 695:149-57. Roch JM, Jin LW, Ninomiya H, Schubert D, Saitoh T. PMID: 8239274.
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    175. The involvement of protein kinase C in activation-induced cell death in T-cell hybridoma. Cell Immunol. 1992 Oct 01; 144(1):217-27. Jin LW, Inaba K, Saitoh T. PMID: 1394438.
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    176. Protein kinases and phosphorylation in neurologic disorders and cell death. Lab Invest. 1991 May; 64(5):596-616. Saitoh T, Masliah E, Jin LW, Cole GM, Wieloch T, Shapiro IP. PMID: 2030574.
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    177. The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion. Neuron. 1989 Dec; 3(6):689-94. Schubert D, Jin LW, Saitoh T, Cole G. PMID: 2518372.
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