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Dominik R Haudenschild

TitleAssociate Professor in Residence
InstitutionUniversity of California Davis
DepartmentOrthopaedic Surgery
Phone916-734-5015
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    Collapse Research 
    Collapse Research Activities and Funding
    Multivalent Presentation of Growth Factors Regulates Cellular Responses
    NIH/NIAMS R01AR070239Apr 10, 2017 - Jan 31, 2022
    Role: Principal Investigator
    Novel Early Intervention to Prevent Post-Traumatic Osteoarthritis
    NIH/NIAMS R21AR063348Aug 1, 2012 - May 31, 2014
    Role: Principal Investigator
    Identification of Mechanoresponsive Promoter Elements in Chondrogenesis
    NIH/NIAMS R03AR061038Apr 1, 2011 - Mar 31, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Haudenschild DR, Carlson AK, Zignego DL, Yik JHN, Hilmer JK, June RK. Inhibition of Early Response Genes Prevents Changes in Global Joint Metabolomic Profiles in Mouse Post-Traumatic Osteoarthritis. Osteoarthritis Cartilage. 2018 Dec 17. PMID: 30572121.
      View in: PubMed
    2. Tran V, Karsai A, Fong MC, Cai W, Yik JHN, Klineberg E, Haudenschild DR, Liu GY. Label-Free and Direct Visualization of Multivalent Binding of Bone Morphogenetic Protein-2 with Cartilage Oligomeric Matrix Protein. J Phys Chem B. 2018 Dec 15. PMID: 30554512.
      View in: PubMed
    3. Shieh AK, Singh SG, Nathe C, Lian E, Haudenschild DR, Nolta JA, Lee CA, Giza E, Kreulen CD. Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus. Cartilage. 2018 Aug 29; 1947603518796125. PMID: 30156865.
      View in: PubMed
    4. Hu Z, Chen Y, Song L, Yik JHN, Haudenschild DR, Fan S. Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation. Front Pharmacol. 2018; 9:174. PMID: 29773986.
      View in: PubMed
    5. Robbins MA, Haudenschild DR, Wegner AM, Klineberg EO. Stem Cells in Spinal Fusion. Global Spine J. 2017 Dec; 7(8):801-810. PMID: 29238646.
      View in: PubMed
    6. Refaat M, Klineberg EO, Fong MC, Garcia TC, Leach JK, Haudenschild DR. Binding to COMP Reduces the BMP2 Dose for Spinal Fusion in a Rat Model. Spine (Phila Pa 1976). 2016 Jul 15; 41(14):E829-36. PMID: 26679888.
      View in: PubMed
    7. Chubinskaya S, Haudenschild D, Gasser S, Stannard J, Krettek C, Borrelli J. Articular Cartilage Injury and Potential Remedies. J Orthop Trauma. 2015 Dec; 29 Suppl 12:S47-52. PMID: 26584267.
      View in: PubMed
    8. Fukui T, Tenborg E, Yik JH, Haudenschild DR. In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury. Biochem Biophys Res Commun. 2015 May 08; 460(3):741-6. PMID: 25817731; PMCID: PMC4426085.
    9. Khorasani MS, Diko S, Hsia AW, Anderson MJ, Genetos DC, Haudenschild DR, Christiansen BA. Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice. Arthritis Res Ther. 2015 Feb 16; 17:30. PMID: 25888819; PMCID: PMC4355375.
    10. Haudenschild DR, Yik JH. Reply: To PMID 24470357. Arthritis Rheumatol. 2014 Dec; 66(12):3526. PMID: 25154864.
      View in: PubMed
    11. Acharya C, Yik JH, Kishore A, Van Dinh V, Di Cesare PE, Haudenschild DR. Cartilage oligomeric matrix protein and its binding partners in the cartilage extracellular matrix: interaction, regulation and role in chondrogenesis. Matrix Biol. 2014 Jul; 37:102-11. PMID: 24997222.
      View in: PubMed
    12. Yik JH, Hu Z, Kumari R, Christiansen BA, Haudenschild DR. Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines. Arthritis Rheumatol. 2014 Jun; 66(6):1537-46. PMID: 24470357; PMCID: PMC4127300.
    13. Yik JH, Li H, Acharya C, Kumari R, Fierro F, Haudenschild DR, Nolta J, Di Cesare PE. The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation. Cartilage. 2013 Oct; 4(4):329-38. PMID: 26069677; PMCID: PMC4297155.
    14. Lockwood KA, Chu BT, Anderson MJ, Haudenschild DR, Christiansen BA. Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis. J Orthop Res. 2014 Jan; 32(1):79-88. PMID: 24019199; PMCID: PMC4140447.
    15. Hong E, Yik J, Amanatullah DF, Di Cesare PE, Haudenschild DR. c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. Cartilage. 2013 Apr; 4(2):177-86. PMID: 26069660; PMCID: PMC4297105.
    16. Ishida K, Acharya C, Christiansen BA, Yik JH, DiCesare PE, Haudenschild DR. Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2. Bone. 2013 Jul; 55(1):23-35. PMID: 23528838.
      View in: PubMed
    17. Ishida K, Haudenschild DR. Interactions between FGF21 and BMP-2 in osteogenesis. Biochem Biophys Res Commun. 2013 Mar 22; 432(4):677-82. PMID: 23416071.
      View in: PubMed
    18. Amanatullah DF, Lu J, Hecht J, Posey K, Yik J, Di Cesare PE, Haudenschild DR. Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene. Tissue Eng Part A. 2012 Sep; 18(17-18):1882-9. PMID: 22764748; PMCID: PMC3432897.
    19. Kumari R, Li H, Haudenschild DR, Fierro F, Carlson CS, Overn P, Gupta L, Gupta K, Nolta J, Yik JH, Di Cesare PE. The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Carcinogenesis. 2012 Nov; 33(11):2076-83. PMID: 22847180.
      View in: PubMed
    20. Haudenschild DR, Hong E, Hatcher S, Jamali AA. Chondrogenic potential and homogeneity of cell populations of donor and recipient cells in a fresh osteochondral allograft: a case report. J Bone Joint Surg Am. 2012 Feb 01; 94(3):e17. PMID: 22298063.
      View in: PubMed
    21. Haudenschild DR, Hong E, Yik JH, Chromy B, Mörgelin M, Snow KD, Acharya C, Takada Y, Di Cesare PE. Enhanced activity of transforming growth factor ß1 (TGF-ß1) bound to cartilage oligomeric matrix protein. J Biol Chem. 2011 Dec 16; 286(50):43250-8. PMID: 21940632; PMCID: PMC3234822.
    22. Hong E, Di Cesare PE, Haudenschild DR. Role of c-Maf in Chondrocyte Differentiation: A Review. Cartilage. 2011 Jan; 2(1):27-35. PMID: 26069566; PMCID: PMC4300789.
    23. Kokubu T, Haudenschild DR, Moseley TA, Rose L, Reddi AH. Immunolocalization of IL-17A, IL-17B, and their receptors in chondrocytes during fracture healing. J Histochem Cytochem. 2008 Feb; 56(2):89-95. PMID: 17827167; PMCID: PMC2324170.
    24. Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH. Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA. Prostate. 2006 Sep 01; 66(12):1268-74. PMID: 16688746.
      View in: PubMed
    25. You Z, Shi XB, DuRaine G, Haudenschild D, Tepper CG, Lo SH, Gandour-Edwards R, de Vere White RW, Reddi AH. Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer. Cancer Res. 2006 Jan 01; 66(1):175-83. PMID: 16397230.
      View in: PubMed
    26. Haudenschild DR, Palmer SM, Moseley TA, You Z, Reddi AH. Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer. Cancer Res. 2004 Nov 15; 64(22):8276-84. PMID: 15548695.
      View in: PubMed
    27. Haudenschild D, Moseley T, Rose L, Reddi AH. Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J Biol Chem. 2002 Feb 08; 277(6):4309-16. PMID: 11706037.
      View in: PubMed