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Kent E Pinkerton

Title(s)Professor, General Pediatrics
SchoolUniversity of California, Davis
Phone530-752-8334
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    Collapse Research 
    Collapse Research Activities and Funding
    Effects of e-cigarette exposure during pregnancy on offspring lung function and disease: Characterization of pulmonary, intergenerational, and epigenetic effects
    NIH/NHLBI R01HL144384Sep 14, 2018 - Aug 31, 2022
    Role: Co-Principal Investigator
    Respiratory and Ocular Toxicity of Inhaled Nanomaterials
    NIH/NIEHS U01ES027288Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Agriculture and Climate Change Impacts on Workers' Health and Safety
    CDC/NIOSH U01OH010969Sep 1, 2016 - Aug 31, 2019
    Role: Principal Investigator
    Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology
    NIH/NIEHS U01ES020127Sep 27, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Respiratory Health Effects of Global Climate Change Workshop
    NIH/NIEHS R13ES019427May 10, 2010 - Apr 30, 2011
    Role: Principal Investigator
    Novel approaches to evaluate carbon nanotube health impacts
    NIH/NIEHS RC1ES018232Sep 25, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Environmental Influences on Perinatal Lung Development
    NIH/NIEHS R01ES011634May 1, 2002 - Feb 28, 2008
    Role: Principal Investigator
    Reducing occupational exposure to zoonotic pathogens in California dairy farm workers
    CDC/NIOSH U54OH007550Sep 30, 2001 - Sep 29, 2021
    Role: Co-Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R29ES004338Jul 1, 1986 - Feb 28, 1992
    Role: Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R23ES004338Jul 1, 1986 - Dec 31, 1988
    Role: Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R23ES003634Jan 1, 1986 - Jun 30, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pinkerton KE, Chen CY, Mack SM, Upadhyay P, Wu CW, Yuan W. Cardiopulmonary Health Effects of Airborne Particulate Matter: Correlating Animal Toxicology to Human Epidemiology. Toxicol Pathol. 2019 Oct 23; 192623319879091. PMID: 31645209.
      View in: PubMed
    2. Wei H, Zhang Y, Song S, Pinkerton KE, Geng H, Ro CU. Alveolar macrophage reaction to PM2.5 of hazy day in vitro: Evaluation methods and mitochondrial screening to determine mechanisms of biological effect. Ecotoxicol Environ Saf. 2019 Jun 15; 174:566-573. PMID: 30870657.
      View in: PubMed
    3. Mack S, Shin J, Ahn Y, Castaneda AR, Peake J, Fulgar C, Zhang J, Cho YH, Pinkerton KE. Age-dependent pulmonary reactivity to house dust mite allergen: a model of adult-onset asthma? Am J Physiol Lung Cell Mol Physiol. 2019 May 01; 316(5):L757-L763. PMID: 30840481.
      View in: PubMed
    4. Wang Z, Wang L, Tapa S, Pinkerton KE, Chen CY, Ripplinger CM. Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model. Environ Health Perspect. 2018 12; 126(12):127001. PMID: 30675795.
      View in: PubMed
    5. Albrengues J, Shields MA, Ng D, Park CG, Ambrico A, Poindexter ME, Upadhyay P, Uyeminami DL, Pommier A, Küttner V, Bružas E, Maiorino L, Bautista C, Carmona EM, Gimotty PA, Fearon DT, Chang K, Lyons SK, Pinkerton KE, Trotman LC, Goldberg MS, Yeh JT, Egeblad M. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. 2018 09 28; 361(6409). PMID: 30262472.
      View in: PubMed
    6. Xu J, Qiu X, Liang Z, Smiley-Jewell S, Lu F, Yu M, Pinkerton KE, Zhao D, Shi B. Exposure to tobacco smoke increases bone loss in spontaneously hypertensive rats. Inhal Toxicol. 2018 05; 30(6):229-238. PMID: 30257116.
      View in: PubMed
    7. Smit-McBride Z, Nguyen J, Elliott GW, Wang Z, McBride RA, Nguyen AT, Oltjen SL, Yiu G, Thomasy SM, Pinkerton KE, Lee ES, Cunefare D, Farsiu S, Morse LS. Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. Mol Vis. 2018; 24:633-646. PMID: 30294202.
      View in: PubMed
    8. Castañeda AR, Vogel CFA, Bein KJ, Hughes HK, Smiley-Jewell S, Pinkerton KE. Ambient particulate matter enhances the pulmonary allergic immune response to house dust mite in a BALB/c mouse model by augmenting Th2- and Th17-immune responses. Physiol Rep. 2018 09; 6(18):e13827. PMID: 30230272.
      View in: PubMed
    9. Pinkerton KE, Poindexter ME. Harmful Interruptions: Impact of Smoking Patterns on Tumorigenesis and Emphysema. Am J Respir Cell Mol Biol. 2018 08; 59(2):133-134. PMID: 29864376.
      View in: PubMed
    10. Zhang J, Fulgar CC, Mar T, Young DE, Zhang Q, Bein KJ, Cui L, Castañeda A, Vogel CFA, Sun X, Li W, Smiley-Jewell S, Zhang Z, Pinkerton KE. TH17-Induced Neutrophils Enhance the Pulmonary Allergic Response Following BALB/c Exposure to House Dust Mite Allergen and Fine Particulate Matter From California and China. Toxicol Sci. 2018 08 01; 164(2):627-643. PMID: 29846732.
      View in: PubMed
    11. Rice MB, Motto Malea N, Pinkerton KE, Schwartz J, Nadeau KC, Browner CM, Whitehouse S, Thurston GD. Realizing the Paris Climate Agreement to Improve Cardiopulmonary Health. Where Science Meets Policy. Ann Am Thorac Soc. 2018 07; 15(7):791-798. PMID: 29652522.
      View in: PubMed
    12. Castañeda AR, Pinkerton KE, Bein KJ, Magaña-Méndez A, Yang HT, Ashwood P, Vogel CFA. Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization. Toxicol Lett. 2018 Aug; 292:85-96. PMID: 29689377.
      View in: PubMed
    13. Miller LA, Royer CM, Pinkerton KE, Schelegle ES. Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. ILAR J. 2017 12 01; 58(2):269-280. PMID: 29216343.
      View in: PubMed
    14. Gordon SB, Buist AS, Hopewell P, Pinkerton K, Sly P, West TE, Moschovis P, Accinelli RA, Cruz ÁA, Adhikari NKJ. How Do We "Help the World Breathe"? Am J Respir Crit Care Med. 2017 Nov 01; 196(9):1100-1102. PMID: 29090965.
      View in: PubMed
    15. Hopkins LE, Laing EA, Peake JL, Uyeminami D, Mack SM, Li X, Smiley-Jewell S, Pinkerton KE. Repeated Iron-Soot Exposure and Nose-to-brain Transport of Inhaled Ultrafine Particles. Toxicol Pathol. 2018 01; 46(1):75-84. PMID: 28914166.
      View in: PubMed
    16. Ferrini M, Carvalho S, Cho YH, Postma B, Miranda Marques L, Pinkerton K, Roberts K, Jaffar Z. Prenatal tobacco smoke exposure predisposes offspring mice to exacerbated allergic airway inflammation associated with altered innate effector function. Part Fibre Toxicol. 2017 08 22; 14(1):30. PMID: 28830530.
      View in: PubMed
    17. Cole E, Brown TA, Pinkerton KE, Postma B, Malany K, Yang M, Kim YJ, Hamilton RF, Holian A, Cho YH. Perinatal exposure to environmental tobacco smoke is associated with changes in DNA methylation that precede the adult onset of lung disease in a mouse model. Inhal Toxicol. 2017 08; 29(10):435-442. PMID: 29124997.
      View in: PubMed
    18. Sun X, Wei H, Young DE, Bein KJ, Smiley-Jewell SM, Zhang Q, Fulgar CCB, Castañeda AR, Pham AK, Li W, Pinkerton KE. Differential pulmonary effects of wintertime California and China particulate matter in healthy young mice. Toxicol Lett. 2017 Aug 15; 278:1-8. PMID: 28698096.
      View in: PubMed
    19. Behrsing H, Hill E, Raabe H, Tice R, Fitzpatrick S, Devlin R, Pinkerton K, Oberdörster G, Wright C, Wieczorek R, Aufderheide M, Steiner S, Krebs T, Asgharian B, Corley R, Oldham M, Adamson J, Li X, Rahman I, Grego S, Chu PH, McCullough S, Curren R. In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use. Altern Lab Anim. 2017 Jul; 45(3):117-158. PMID: 28816053.
      View in: PubMed
    20. Christensen S, Jaffar Z, Cole E, Porter V, Ferrini M, Postma B, Pinkerton KE, Yang M, Kim YJ, Montrose L, Roberts K, Holian A, Cho YH. Prenatal environmental tobacco smoke exposure increases allergic asthma risk with methylation changes in mice. Environ Mol Mutagen. 2017 07; 58(6):423-433. PMID: 28543436.
      View in: PubMed
    21. Castañeda AR, Bein KJ, Smiley-Jewell S, Pinkerton KE. Fine particulate matter (PM2.5) enhances allergic sensitization in BALB/c mice. J Toxicol Environ Health A. 2017; 80(4):197-207. PMID: 28494199.
      View in: PubMed
    22. Zhao D, Qiu X, Wang B, Wang Z, Wang W, Ouyang J, Silva RM, Shi X, Kang K, Xu D, Li C, Zhong S, Zhang Y, Pinkerton KE. Epiphyseal Arterial Network and Inferior Retinacular Artery Seem Critical to Femoral Head Perfusion in Adults With Femoral Neck Fractures. Clin Orthop Relat Res. 2017 Aug; 475(8):2011-2023. PMID: 28315184.
      View in: PubMed
    23. Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK. Environment, Global Climate Change, and Cardiopulmonary Health. Am J Respir Crit Care Med. 2017 03 15; 195(6):718-724. PMID: 27654004.
      View in: PubMed
    24. Antony VB, Redlich CA, Pinkerton KE, Balmes J, Harkema JR. National Institute of Environmental Health Sciences: 50 Years of Advancing Science and Improving Lung Health. Am J Respir Crit Care Med. 2016 11 15; 194(10):1190-1195. PMID: 27668911.
      View in: PubMed
    25. Shen YH, Pham AK, Davis B, Smiley-Jewell S, Wang L, Kodavanti UP, Takeuchi M, Tancredi DJ, Pinkerton KE. Sex and strain-based inflammatory response to repeated tobacco smoke exposure in spontaneously hypertensive and Wistar Kyoto rats. Inhal Toxicol. 2016 12; 28(14):677-685. PMID: 27829308.
      View in: PubMed
    26. Barupal DK, Pinkerton KE, Hood C, Kind T, Fiehn O. Environmental Tobacco Smoke Alters Metabolic Systems in Adult Rats. Chem Res Toxicol. 2016 11 21; 29(11):1818-1827. PMID: 27788581.
      View in: PubMed
    27. Kuempel ED, Jaurand MC, Møller P, Morimoto Y, Kobayashi N, Pinkerton KE, Sargent LM, Vermeulen RC, Fubini B, Kane AB. Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans. Crit Rev Toxicol. 2017 Jan; 47(1):1-58. PMID: 27537422.
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    28. Hoang LL, Nguyen YP, Aspeé R, Bolton SJ, Shen YH, Wang L, Kenyon NJ, Smiley-Jewell S, Pinkerton KE. Temporal and Spatial Expression of Transforming Growth Factor-ß after Airway Remodeling to Tobacco Smoke in Rats. Am J Respir Cell Mol Biol. 2016 06; 54(6):872-81. PMID: 26637070.
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    29. Patchin ES, Anderson DS, Silva RM, Uyeminami DL, Scott GM, Guo T, Van Winkle LS, Pinkerton KE. Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain. Environ Health Perspect. 2016 12; 124(12):1870-1875. PMID: 27152509.
      View in: PubMed
    30. Castañeda AR, Pinkerton KE. Investigating the Effects of Particulate Matter on House Dust Mite and Ovalbumin Allergic Airway Inflammation in Mice. Curr Protoc Toxicol. 2016 05 04; 68:18.18.1-18.18.18. PMID: 27145110.
      View in: PubMed
    31. Brown TA, Holian A, Pinkerton KE, Lee JW, Cho YH. Early life exposure to environmental tobacco smoke alters immune response to asbestos via a shift in inflammatory phenotype resulting in increased disease development. Inhal Toxicol. 2016 07; 28(8):349-56. PMID: 27138493.
      View in: PubMed
    32. Silva RM, Anderson DS, Peake J, Edwards PC, Patchin ES, Guo T, Gordon T, Chen LC, Sun X, Van Winkle LS, Pinkerton KE. Aerosolized Silver Nanoparticles in the Rat Lung and Pulmonary Responses over Time. Toxicol Pathol. 2016 07; 44(5):673-86. PMID: 27025955.
      View in: PubMed
    33. Calvo-Lorenzo MS, Hulbert LE, Fowler AL, Louie A, Gershwin LJ, Pinkerton KE, Ballou MA, Klasing KC, Mitloehner FM. Wooden hutch space allowance influences male Holstein calf health, performance, daily lying time, and respiratory immunity. J Dairy Sci. 2016 Jun; 99(6):4678-4692. PMID: 27016829.
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    34. Kurt OK, Zhang J, Pinkerton KE. Pulmonary health effects of air pollution. Curr Opin Pulm Med. 2016 Mar; 22(2):138-43. PMID: 26761628.
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    35. Edderkaoui M, Xu S, Chheda C, Morvaridi S, Hu RW, Grippo PJ, Mascariñas E, Principe DR, Knudsen B, Xue J, Habtezion A, Uyeminami D, Pinkerton KE, Pandol SJ. HDAC3 mediates smoking-induced pancreatic cancer. Oncotarget. 2016 Feb 16; 7(7):7747-60. PMID: 26745602.
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    36. Liu YX, Karsai A, Anderson DS, Silva RM, Uyeminami DL, Van Winkle LS, Pinkerton KE, Liu GY. Single-Cell Mechanics Provides an Effective Means To Probe in Vivo Interactions between Alveolar Macrophages and Silver Nanoparticles. J Phys Chem B. 2015 Dec 10; 119(49):15118-29. PMID: 26562364.
      View in: PubMed
    37. Lee JW, Jaffar Z, Pinkerton KE, Porter V, Postma B, Ferrini M, Holian A, Roberts K, Cho YH. Alterations in DNA methylation and airway hyperreactivity in response to in utero exposure to environmental tobacco smoke. Inhal Toxicol. 2015; 27(13):724-30. PMID: 26525176.
      View in: PubMed
    38. Plummer LE, Carosino CM, Bein KJ, Zhao Y, Willits N, Smiley-Jewell S, Wexler AS, Pinkerton KE. Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley. Atmos Environ (1994). 2015 Oct 01; 119:174-181. PMID: 26568698.
      View in: PubMed
    39. Belafsky PC, Peake J, Smiley-Jewell SM, Verma SP, Dworkin-Valenti J, Pinkerton KE. Soot and house dust mite allergen cause eosinophilic laryngitis in an animal model. Laryngoscope. 2016 Jan; 126(1):108-12. PMID: 26197967.
      View in: PubMed
    40. Pinkerton KE, Harbaugh M, Han MK, Jourdan Le Saux C, Van Winkle LS, Martin WJ, Kosgei RJ, Carter EJ, Sitkin N, Smiley-Jewell SM, George M. Women and Lung Disease. Sex Differences and Global Health Disparities. Am J Respir Crit Care Med. 2015 Jul 01; 192(1):11-6. PMID: 25945507.
      View in: PubMed
    41. Nel AE, Parak WJ, Chan WC, Xia T, Hersam MC, Brinker CJ, Zink JI, Pinkerton KE, Baer DR, Weiss PS. Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization? ACS Nano. 2015 Jun 23; 9(6):5627-30. PMID: 26100220.
      View in: PubMed
    42. Nording ML, Yang J, Hoang L, Zamora V, Uyeminami D, Espiritu I, Pinkerton KE, Hammock BD, Luria A. Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. J Metabolomics. 2015 Apr; 1. PMID: 27076918.
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    43. Li X, Xue M, Raabe OG, Aaron HL, Eisen EA, Evans JE, Hayes FA, Inaga S, Tagmount A, Takeuchi M, Vulpe C, Zink JI, Risbud SH, Pinkerton KE. Aerosol droplet delivery of mesoporous silica nanoparticles: A strategy for respiratory-based therapeutics. Nanomedicine. 2015 Aug; 11(6):1377-85. PMID: 25819886.
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    44. Ewart GW, Rom WN, Braman SS, Pinkerton KE. From closing the atmospheric ozone hole to reducing climate change. Lessons learned. Ann Am Thorac Soc. 2015 Feb; 12(2):247-51. PMID: 25706493.
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    45. Zhu L, Di PY, Wu R, Pinkerton KE, Chen Y. Repression of CC16 by cigarette smoke (CS) exposure. PLoS One. 2015; 10(1):e0116159. PMID: 25635997.
      View in: PubMed
    46. Silva RM, Anderson DS, Franzi LM, Peake JL, Edwards PC, Van Winkle LS, Pinkerton KE. Pulmonary effects of silver nanoparticle size, coating, and dose over time upon intratracheal instillation. Toxicol Sci. 2015 Mar; 144(1):151-62. PMID: 25628415.
      View in: PubMed
    47. Anderson DS, Patchin ES, Silva RM, Uyeminami DL, Sharmah A, Guo T, Das GK, Brown JM, Shannahan J, Gordon T, Chen LC, Pinkerton KE, Van Winkle LS. Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung. Toxicol Sci. 2015 Apr; 144(2):366-81. PMID: 25577195.
      View in: PubMed
    48. Carosino CM, Bein KJ, Plummer LE, Castañeda AR, Zhao Y, Wexler AS, Pinkerton KE. Allergic airway inflammation is differentially exacerbated by daytime and nighttime ultrafine and submicron fine ambient particles: heme oxygenase-1 as an indicator of PM-mediated allergic inflammation. J Toxicol Environ Health A. 2015; 78(4):254-66. PMID: 25679046.
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    49. Davidson RA, Anderson DS, Van Winkle LS, Pinkerton KE, Guo T. Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy. J Phys Chem A. 2015 Jan 15; 119(2):281-9. PMID: 25517690.
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    50. Mirowsky JE, Jin L, Thurston G, Lighthall D, Tyner T, Horton L, Galdanes K, Chillrud S, Ross J, Pinkerton KE, Chen LC, Lippmann M, Gordon T. In vitro and in vivo toxicity of urban and rural particulate matter from California. Atmos Environ (1994). 2015 Feb; 103:256-262. PMID: 26478712.
      View in: PubMed
    51. Hopkins LE, Patchin ES, Chiu PL, Brandenberger C, Smiley-Jewell S, Pinkerton KE. Nose-to-brain transport of aerosolised quantum dots following acute exposure. Nanotoxicology. 2014 Dec; 8(8):885-93. PMID: 24040866.
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    52. Van Winkle LS, Bein K, Anderson D, Pinkerton KE, Tablin F, Wilson D, Wexler AS. Biological dose response to PM2.5: effect of particle extraction method on platelet and lung responses. Toxicol Sci. 2015 Feb; 143(2):349-59. PMID: 25389146.
      View in: PubMed
    53. Silva RM, Xu J, Saiki C, Anderson DS, Franzi LM, Vulpe CD, Gilbert B, Van Winkle LS, Pinkerton KE. Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation. Part Fibre Toxicol. 2014 Oct 08; 11:52. PMID: 25292367.
      View in: PubMed
    54. Anderson DS, Silva RM, Lee D, Edwards PC, Sharmah A, Guo T, Pinkerton KE, Van Winkle LS. Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition. Nanotoxicology. 2015; 9(5):591-602. PMID: 25231189.
      View in: PubMed
    55. Silva RM, Doudrick K, Franzi LM, TeeSy C, Anderson DS, Wu Z, Mitra S, Vu V, Dutrow G, Evans JE, Westerhoff P, Van Winkle LS, Raabe OG, Pinkerton KE. Instillation versus inhalation of multiwalled carbon nanotubes: exposure-related health effects, clearance, and the role of particle characteristics. ACS Nano. 2014 Sep 23; 8(9):8911-31. PMID: 25144856.
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    56. Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Reply: the largest problem with climate change policy is not a future event. Am J Respir Crit Care Med. 2014 Jul 01; 190(1):117. PMID: 24983223.
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    57. Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Climate change. A global threat to cardiopulmonary health. Am J Respir Crit Care Med. 2014 Mar 01; 189(5):512-9. PMID: 24400619.
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    58. Tran TN, Kosaraju MG, Tamamizu-Kato S, Akintunde O, Zheng Y, Bielicki JK, Pinkerton K, Uchida K, Lee YY, Narayanaswami V. Acrolein modification impairs key functional features of rat apolipoprotein E: identification of modified sites by mass spectrometry. Biochemistry. 2014 Jan 21; 53(2):361-75. PMID: 24325674.
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    59. Madl AK, Plummer LE, Carosino C, Pinkerton KE. Nanoparticles, lung injury, and the role of oxidant stress. Annu Rev Physiol. 2014; 76:447-65. PMID: 24215442.
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    60. Wang X, Ji Z, Chang CH, Zhang H, Wang M, Liao YP, Lin S, Meng H, Li R, Sun B, Winkle LV, Pinkerton KE, Zink JI, Xia T, Nel AE. Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small. 2014 Jan 29; 10(2):385-98. PMID: 24039004.
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    61. Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, Kuempel E, Lafranconi M, Landsiedel R, Malloy T, Miller MB, Morris J, Moss K, Oberdorster G, Pinkerton K, Pleus RC, Shatkin JA, Thomas R, Tolaymat T, Wang A, Wong J. A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. ACS Nano. 2013 Aug 27; 7(8):6422-33. PMID: 23924032.
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    62. Fetterman JL, Pompilius M, Westbrook DG, Uyeminami D, Brown J, Pinkerton KE, Ballinger SW. Developmental exposure to second-hand smoke increases adult atherogenesis and alters mitochondrial DNA copy number and deletions in apoE(-/-) mice. PLoS One. 2013; 8(6):e66835. PMID: 23825571.
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    63. Bonner JC, Silva RM, Taylor AJ, Brown JM, Hilderbrand SC, Castranova V, Porter D, Elder A, Oberdörster G, Harkema JR, Bramble LA, Kavanagh TJ, Botta D, Nel A, Pinkerton KE. Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect. 2013 Jun; 121(6):676-82. PMID: 23649427.
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    64. Silva RM, Teesy C, Franzi L, Weir A, Westerhoff P, Evans JE, Pinkerton KE. Biological response to nano-scale titanium dioxide (TiO2): role of particle dose, shape, and retention. J Toxicol Environ Health A. 2013; 76(16):953-72. PMID: 24156719.
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    65. Hooper MJ, Ankley GT, Cristol DA, Maryoung LA, Noyes PD, Pinkerton KE. Interactions between chemical and climate stressors: a role for mechanistic toxicology in assessing climate change risks. Environ Toxicol Chem. 2013 Jan; 32(1):32-48. PMID: 23136056.
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    66. Davis BB, Zeki AA, Bratt JM, Wang L, Filosto S, Walby WF, Kenyon NJ, Goldkorn T, Schelegle ES, Pinkerton KE. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. Eur Respir J. 2013 Aug; 42(2):350-61. PMID: 23180589.
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    67. Claude JA, Grimm A, Savage HP, Pinkerton KE. Perinatal exposure to environmental tobacco smoke (ETS) enhances susceptibility to viral and secondary bacterial infections. Int J Environ Res Public Health. 2012 Oct 31; 9(11):3954-64. PMID: 23202826.
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    68. Berman JD, Fann N, Hollingsworth JW, Pinkerton KE, Rom WN, Szema AM, Breysse PN, White RH, Curriero FC. Health benefits from large-scale ozone reduction in the United States. Environ Health Perspect. 2012 Oct; 120(10):1404-10. PMID: 22809899.
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    69. Plopper CG, Joad JP, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Lasley WL, Buckpitt AR, Pinkerton KE, Tarkington BK, Davis S, Nishio SJ, Gershwin LJ, Wu R, Hyde DM. Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clin Exp Allergy. 2012 Jul; 42(7):1104-18. PMID: 22702509.
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    70. Tell LA, Stephens K, Teague SV, Pinkerton KE, Raabe OG. Study of nebulization delivery of aerosolized fluorescent microspheres to the avian respiratory tract. Avian Dis. 2012 Jun; 56(2):381-6. PMID: 22856198.
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    71. Barupal DK, Haldiya PK, Wohlgemuth G, Kind T, Kothari SL, Pinkerton KE, Fiehn O. MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. BMC Bioinformatics. 2012 May 16; 13:99. PMID: 22591066.
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    72. Davis BB, Shen YH, Tancredi DJ, Flores V, Davis RP, Pinkerton KE. Leukocytes are recruited through the bronchial circulation to the lung in a spontaneously hypertensive rat model of COPD. PLoS One. 2012; 7(3):e33304. PMID: 22457750.
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    73. Pinkerton KE, Rom WN, Akpinar-Elci M, Balmes JR, Bayram H, Brandli O, Hollingsworth JW, Kinney PL, Margolis HG, Martin WJ, Sasser EN, Smith KR, Takaro TK. An official American Thoracic Society workshop report: Climate change and human health. Proc Am Thorac Soc. 2012 Mar; 9(1):3-8. PMID: 22421581.
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    74. Zhao X, Bu DX, Hayfron K, Pinkerton KE, Bevins CL, Lichtman A, Wiedeman J. A combination of secondhand cigarette smoke and Chlamydia pneumoniae accelerates atherosclerosis. Atherosclerosis. 2012 May; 222(1):59-66. PMID: 22410122.
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    75. Plummer LE, Ham W, Kleeman MJ, Wexler A, Pinkerton KE. Influence of season and location on pulmonary response to California's San Joaquin Valley airborne particulate matter. J Toxicol Environ Health A. 2012; 75(5):253-71. PMID: 22409489.
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    76. Balmes J, Pinkerton K. Clearing the air. Am J Respir Crit Care Med. 2012 Jan 01; 185(1):1-2. PMID: 22210780.
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    77. Butler LM, Smiley-Jewell S, Pinkerton KE. Can nutrition lessen the effects of secondhand smoke exposure among children? Rev Environ Health. 2012; 27(2-3):75-84. PMID: 23047934.
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    78. Wang L, Yang J, Guo L, Uyeminami D, Dong H, Hammock BD, Pinkerton KE. Use of a soluble epoxide hydrolase inhibitor in smoke-induced chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2012 May; 46(5):614-22. PMID: 22180869.
      View in: PubMed
    79. Davis BB, Liu JY, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochem Biophys Res Commun. 2011 Jul 08; 410(3):494-500. PMID: 21683067.
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    80. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Distinct tachykinin NK(1) receptor function in primate nucleus tractus solitarius neurons is dysregulated after second-hand tobacco smoke exposure. Br J Pharmacol. 2011 Jun; 163(4):782-91. PMID: 21323902.
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    81. Herr CE, Ghosh R, Dostal M, Skokanova V, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Yap PS, Frost JD, Sram R, Hertz-Picciotto I. Exposure to air pollution in critical prenatal time windows and IgE levels in newborns. Pediatr Allergy Immunol. 2011 Feb; 22(1 Pt 1):75-84. PMID: 20609135.
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    82. Case BW, Abraham JL, Meeker G, Pooley FD, Pinkerton KE. Applying definitions of "asbestos" to environmental and "low-dose" exposure levels and health effects, particularly malignant mesothelioma. J Toxicol Environ Health B Crit Rev. 2011; 14(1-4):3-39. PMID: 21534084.
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    83. Sandberg KL, Pinkerton KE, Poole SD, Minton PA, Sundell HW. Fetal nicotine exposure increases airway responsiveness and alters airway wall composition in young lambs. Respir Physiol Neurobiol. 2011 Apr 30; 176(1-2):57-67. PMID: 21195212.
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    84. Harrison CM, Pompilius M, Pinkerton KE, Ballinger SW. Mitochondrial oxidative stress significantly influences atherogenic risk and cytokine-induced oxidant production. Environ Health Perspect. 2011 May; 119(5):676-81. PMID: 21169125.
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    85. Fukuda M, Kobayashi K, Hirono Y, Miyagawa M, Ishida T, Ejiogu EC, Sawai M, Pinkerton KE, Takeuchi M. Jungle honey enhances immune function and antitumor activity. Evid Based Complement Alternat Med. 2011; 2011:908743. PMID: 19141489.
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    86. Wang L, Green FH, Smiley-Jewell SM, Pinkerton KE. Susceptibility of the aging lung to environmental injury. Semin Respir Crit Care Med. 2010 Oct; 31(5):539-53. PMID: 20941655.
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    87. Villablanca AC, Pinkerton KE, Rutledge JC. Maternal and neonatal exposure to environmental tobacco smoke targets pro-inflammatory genes in neonatal arteries. J Cardiovasc Transl Res. 2010 Dec; 3(6):696-703. PMID: 20890690.
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    88. Westbrook DG, Anderson PG, Pinkerton KE, Ballinger SW. Perinatal tobacco smoke exposure increases vascular oxidative stress and mitochondrial damage in non-human primates. Cardiovasc Toxicol. 2010 Sep; 10(3):216-26. PMID: 20668962.
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    89. Herr CE, Dostal M, Ghosh R, Ashwood P, Lipsett M, Pinkerton KE, Sram R, Hertz-Picciotto I. Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths. Environ Health. 2010 Aug 02; 9:46. PMID: 20678227.
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    90. Filosto S, Castillo S, Danielson A, Franzi L, Khan E, Kenyon N, Last J, Pinkerton K, Tuder R, Goldkorn T. Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):350-60. PMID: 20448054.
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    91. Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F. Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation. Inhal Toxicol. 2010 Mar; 22(4):267-76. PMID: 20064101.
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    92. Dey R, Van Winkle L, Ewart G, Balmes J, Pinkerton K. A second chance. Setting a protective ozone standard. Am J Respir Crit Care Med. 2010 Feb 15; 181(4):297-9. PMID: 20130144.
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    93. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs. Eur J Neurosci. 2010 Feb; 31(4):673-84. PMID: 20384811.
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    94. Zhong CY, Zhou YM, Smith KR, Kennedy IM, Chen CY, Aust AE, Pinkerton KE. Oxidative injury in the lungs of neonatal rats following short-term exposure to ultrafine iron and soot particles. J Toxicol Environ Health A. 2010; 73(12):837-47. PMID: 20391124.
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    95. Ishida T, Hirono Y, Yoshikawa K, Hutei Y, Miyagawa M, Sakaguchi I, Pinkerton KE, Takeuchi M. Inhibition of immunological function mediated DNA damage of alveolar macrophages caused by cigarette smoke in mice. Inhal Toxicol. 2009 Dec; 21(14):1229-35. PMID: 19922407.
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    96. Bolton SJ, Pinnion K, Oreffo V, Foster M, Pinkerton KE. Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats. Respir Res. 2009 Nov 24; 10:118. PMID: 19930705.
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    97. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates. Toxicol Appl Pharmacol. 2010 Jan 15; 242(2):199-208. PMID: 19850058.
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    98. Pham H, Bonham AC, Pinkerton KE, Chen CY. Central neuroplasticity and decreased heart rate variability after particulate matter exposure in mice. Environ Health Perspect. 2009 Sep; 117(9):1448-53. PMID: 19750112.
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    99. Mouadeb DA, Belafsky PC, Birchall M, Hood C, Konia T, Pinkerton KE. The effects of allergens and tobacco smoke on the laryngeal mucosa of guinea pigs. Otolaryngol Head Neck Surg. 2009 Apr; 140(4):493-7. PMID: 19328336.
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    100. Woodruff PG, Ellwanger A, Solon M, Cambier CJ, Pinkerton KE, Koth LL. Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice. COPD. 2009 Apr; 6(2):86-94. PMID: 19378221.
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    101. Bailey SM, Mantena SK, Millender-Swain T, Cakir Y, Jhala NC, Chhieng D, Pinkerton KE, Ballinger SW. Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease. Free Radic Biol Med. 2009 Apr 01; 46(7):928-38. PMID: 19280709.
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    102. Rao SP, Sikora L, Hosseinkhani MR, Pinkerton KE, Sriramarao P. Exposure to environmental tobacco smoke induces angiogenesis and leukocyte trafficking in lung microvessels. Exp Lung Res. 2009 Mar; 35(2):119-35. PMID: 19263281.
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    103. Schenker MB, Pinkerton KE, Mitchell D, Vallyathan V, Elvine-Kreis B, Green FH. Pneumoconiosis from agricultural dust exposure among young California farmworkers. Environ Health Perspect. 2009 Jun; 117(6):988-94. PMID: 19590695.
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    104. Wegesser TC, Pinkerton KE, Last JA. California wildfires of 2008: coarse and fine particulate matter toxicity. Environ Health Perspect. 2009 Jun; 117(6):893-7. PMID: 19590679.
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    105. Avdalovic M, Putney L, Tyler N, Finkbeiner W, Pinkerton K, Hyde D. In utero and postnatal exposure to environmental tobacco smoke (ETS) alters alveolar and respiratory bronchiole (RB) growth and development in infant monkeys. Toxicol Pathol. 2009 Feb; 37(2):256-63. PMID: 19332666.
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    106. Plummer LE, Pinkerton KE, Reynolds S, Meschke S, Mitloehner F, Bennett D, Smiley-Jewell S, Schenker MB. Aerosols in the agricultural setting. J Agromedicine. 2009; 14(4):413-6. PMID: 19894162.
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    107. Madl AK, Pinkerton KE. Health effects of inhaled engineered and incidental nanoparticles. Crit Rev Toxicol. 2009; 39(8):629-58. PMID: 19743943.
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    108. Hung PH, Froenicke L, Lin CY, Lyons LA, Miller MG, Pinkerton KE, VandeVoort CA. Effects of environmental tobacco smoke in vivo on rhesus monkey semen quality, sperm function, and sperm metabolism. Reprod Toxicol. 2009 Apr; 27(2):140-8. PMID: 19159676.
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    109. Stenger PC, Alonso C, Zasadzinski JA, Waring AJ, Jung CL, Pinkerton KE. Environmental tobacco smoke effects on lung surfactant film organization. Biochim Biophys Acta. 2009 Feb; 1788(2):358-70. PMID: 19118518.
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    110. Joad JP, Kott KS, Bric JM, Peake JL, Pinkerton KE. Effect of perinatal secondhand tobacco smoke exposure on in vivo and intrinsic airway structure/function in non-human primates. Toxicol Appl Pharmacol. 2009 Feb 01; 234(3):339-44. PMID: 19084550.
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    111. Gospe SM, Joyce JA, Siebert JR, Jack RM, Pinkerton KE. Exposure to environmental tobacco smoke during pregnancy in rats yields less effect on indices of brain cell number and size than does postnatal exposure. Reprod Toxicol. 2009 Jan; 27(1):22-7. PMID: 19059474.
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    112. Ishida T, Pinkerton KE, Takeuchi M. Alveolar macrophage from cigarette smoke-exposed mice inhibits B lymphocyte proliferation stimulated with LPS. Respiration. 2009; 77(1):91-5. PMID: 18984945.
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    113. Pinkerton KE, Zhou Y, Zhong C, Smith KR, Teague SV, Kennedy IM, Ménache MG. Mechanisms of particulate matter toxicity in neonatal and young adult rat lungs. Res Rep Health Eff Inst. 2008 Oct; (135):3-41; discussion 43-52. PMID: 19203021.
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    114. Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE. Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect. Am J Respir Crit Care Med. 2008 Dec 01; 178(11):1130-8. PMID: 18723436.
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    115. Sekizawa S, Chen CY, Bechtold AG, Tabor JM, Bric JM, Pinkerton KE, Joad JP, Bonham AC. Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius second-order lung afferent neurons in young guinea pigs. Eur J Neurosci. 2008 Aug; 28(4):771-81. PMID: 18657181.
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    116. Yu M, Zheng X, Peake J, Joad JP, Pinkerton KE. Perinatal environmental tobacco smoke exposure alters the immune response and airway innervation in infant primates. J Allergy Clin Immunol. 2008 Sep; 122(3):640-7.e1. PMID: 18571708.
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    117. Chen CY, Chow D, Chiamvimonvat N, Glatter KA, Li N, He Y, Pinkerton KE, Bonham AC. Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H632-9. PMID: 18552155.
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    118. Wang L, Joad JP, Zhong C, Pinkerton KE. Effects of environmental tobacco smoke exposure on pulmonary immune response in infant monkeys. J Allergy Clin Immunol. 2008 Aug; 122(2):400-6, 406.e1-5. PMID: 18502491.
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    119. Rom WN, Pinkerton KE, Martin WJ, Forastiere F. Global warming: a challenge to all American Thoracic Society members. Am J Respir Crit Care Med. 2008 May 15; 177(10):1053-4. PMID: 18460457.
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    120. Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke. FASEB J. 2008 May; 22(5):1356-68. PMID: 18450646.
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    121. Yu B, Kodavanti UP, Takeuchi M, Witschi H, Pinkerton KE. Acute tobacco smoke-induced airways inflammation in spontaneously hypertensive rats. Inhal Toxicol. 2008 May; 20(7):623-33. PMID: 18464051.
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    122. Schenker M, Pinkerton K. Research to practice in the agricultural workplace. J Agric Saf Health. 2008 Apr; 14(2):131-3. PMID: 18524280.
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    123. Wang L, Pinkerton KE. Detrimental effects of tobacco smoke exposure during development on postnatal lung function and asthma. Birth Defects Res C Embryo Today. 2008 Mar; 84(1):54-60. PMID: 18383132.
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    124. Zhong CY, Zhou YM, Pinkerton KE. NF-kappaB inhibition is involved in tobacco smoke-induced apoptosis in the lungs of rats. Toxicol Appl Pharmacol. 2008 Jul 15; 230(2):150-8. PMID: 18355884.
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    125. Donaldson K, Borm PJ, Oberdorster G, Pinkerton KE, Stone V, Tran CL. Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles: the key role of the proximal alveolar region. Inhal Toxicol. 2008 Jan; 20(1):53-62. PMID: 18236223.
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    126. Balbus JM, Maynard AD, Colvin VL, Castranova V, Daston GP, Denison RA, Dreher KL, Goering PL, Goldberg AM, Kulinowski KM, Monteiro-Riviere NA, Oberdörster G, Omenn GS, Pinkerton KE, Ramos KS, Rest KM, Sass JB, Silbergeld EK, Wong BA. Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop. Environ Health Perspect. 2007 Nov; 115(11):1654-9. PMID: 18007999.
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    127. Hertz-Picciotto I, Baker RJ, Yap PS, Dostál M, Joad JP, Lipsett M, Greenfield T, Herr CE, Benes I, Shumway RH, Pinkerton KE, Srám R. Early childhood lower respiratory illness and air pollution. Environ Health Perspect. 2007 Oct; 115(10):1510-8. PMID: 17938744.
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    128. Joad JP, Kott KS, Bric JM, Schelegle ES, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE. The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone. Toxicol Appl Pharmacol. 2008 Jan 15; 226(2):153-60. PMID: 17991502.
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    129. Wang L, Pinkerton KE. Air pollutant effects on fetal and early postnatal development. Birth Defects Res C Embryo Today. 2007 Sep; 81(3):144-54. PMID: 17963272.
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    130. Pauluhn J, Carson A, Costa DL, Gordon T, Kodavanti U, Last JA, Matthay MA, Pinkerton KE, Sciuto AM. Workshop summary: phosgene-induced pulmonary toxicity revisited: appraisal of early and late markers of pulmonary injury from animal models with emphasis on human significance. Inhal Toxicol. 2007 Aug; 19(10):789-810. PMID: 17687713.
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    131. Cakir Y, Yang Z, Knight CA, Pompilius M, Westbrook D, Bailey SM, Pinkerton KE, Ballinger SW. Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis. Free Radic Biol Med. 2007 Nov 01; 43(9):1279-88. PMID: 17893041.
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    132. Pinkerton KE, Balmes JR, Fanucchi MV, Rom WN. Ozone, a malady for all ages. Am J Respir Crit Care Med. 2007 Jul 15; 176(2):107-8. PMID: 17617531.
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    133. Wang L, Joad JP, Abel K, Spinner A, Smiley-Jewell S, Liu H, Pinkerton KE. Effects of environmental tobacco smoke on the developing immune system of infant monkeys. J Allergy Clin Immunol. 2007 Aug; 120(2):445-51. PMID: 17482667.
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    134. Golub MS, Slotkin TA, Tarantal AF, Pinkerton KE. Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke. Brain Res. 2007 Jun 02; 1151:102-6. PMID: 17399690.
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    135. Coppens JT, Van Winkle LS, Pinkerton K, Plopper CG. Distribution of Clara cell secretory protein expression in the tracheobronchial airways of rhesus monkeys. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1155-62. PMID: 17237148.
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    136. Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. Life Sci. 2007 May 30; 80(24-25):2191-4. PMID: 17291542.
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    137. Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM. Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology? Toxicol Pathol. 2007 Jan; 35(1):97-110. PMID: 17325978.
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    138. Jasinski J, Pinkerton KE, Kennedy IM, Leppert VJ. Spatially resolved energy electron loss spectroscopy studies of iron oxide nanoparticles. Microsc Microanal. 2006 Oct; 12(5):424-31. PMID: 16984669.
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    139. Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J. 2006 Oct; 20(12):2093-101. PMID: 17012261.
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    140. Mansoor JK, Decile KC, Giri SN, Pinkerton KE, Walby WF, Bratt JM, Grewal H, Margolin SB, Schelegle ES. Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma. Pulm Pharmacol Ther. 2007; 20(6):660-8. PMID: 17049446.
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    141. Kodavanti UP, Schladweiler MC, Ledbetter AD, Ortuno RV, Suffia M, Evansky P, Richards JH, Jaskot RH, Thomas R, Karoly E, Huang YC, Costa DL, Gilmour PS, Pinkerton KE. The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease. Toxicol Sci. 2006 Nov; 94(1):193-205. PMID: 16929007.
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    142. Eaton MM, Gursahani H, Arieli Y, Pinkerton K, Schaefer S. Acute tobacco smoke exposure promotes mitochondrial permeability transition in rat heart. J Toxicol Environ Health A. 2006 Aug; 69(15):1497-510. PMID: 16766481.
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    143. Slotkin TA, Pinkerton KE, Tate CA, Seidler FJ. Alterations of serotonin synaptic proteins in brain regions of neonatal Rhesus monkeys exposed to perinatal environmental tobacco smoke. Brain Res. 2006 Sep 21; 1111(1):30-5. PMID: 16876770.
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    144. Smith KR, Veranth JM, Kodavanti UP, Aust AE, Pinkerton KE. Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. Toxicol Sci. 2006 Oct; 93(2):390-9. PMID: 16840564.
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    145. Tell LA, Smiley-Jewell S, Hinds D, Stephens KE, Teague SV, Plopper CG, Pinkerton KE. An aerosolized fluorescent microsphere technique for evaluating particle deposition in the avian respiratory tract. Avian Dis. 2006 Jun; 50(2):238-44. PMID: 16863074.
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    146. Zhong CY, Zhou YM, Joad JP, Pinkerton KE. Environmental tobacco smoke suppresses nuclear factor-kappaB signaling to increase apoptosis in infant monkey lungs. Am J Respir Crit Care Med. 2006 Aug 15; 174(4):428-36. PMID: 16709937.
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    147. Pinkerton KE, Joad JP. Influence of air pollution on respiratory health during perinatal development. Clin Exp Pharmacol Physiol. 2006 Mar; 33(3):269-72. PMID: 16487273.
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    148. Martin RJ, Wexler RB, Day BJ, Harbeck RJ, Pinkerton KE, Chu HW. Interaction between cigarette smoke and mycoplasma infection: a murine model. COPD. 2006 Mar; 3(1):3-8. PMID: 17175659.
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    149. Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle ES, Gershwin LJ, Pinkerton KE. Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone. Toxicol Appl Pharmacol. 2006 Aug 01; 214(3):237-43. PMID: 16466656.
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    150. Slotkin TA, Pinkerton KE, Seidler FJ. Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. Environ Health Perspect. 2006 Jan; 114(1):34-9. PMID: 16393655.
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    151. Simons CT, Cuellar JM, Moore JA, Pinkerton KE, Uyeminami D, Carstens MI, Carstens E. Nicotinic receptor involvement in antinociception induced by exposure to cigarette smoke. Neurosci Lett. 2005 Dec 02; 389(2):71-6. PMID: 16095820.
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    152. Wiedeman JA, Kaul R, Heuer LS, Thao NN, Pinkerton KE, Wenman WM. Tobacco smoke induces a persistent, but recoverable state in Chlamydia pneumoniae infection of human endothelial cells. Microb Pathog. 2005 Nov-Dec; 39(5-6):197-204. PMID: 16271847.
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    153. Kodavanti UP, Schladweiler MC, Ledbetter AD, McGee JK, Walsh L, Gilmour PS, Highfill JW, Davies D, Pinkerton KE, Richards JH, Crissman K, Andrews D, Costa DL. Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: roles of rat strains used and physicochemical properties. Environ Health Perspect. 2005 Nov; 113(11):1561-8. PMID: 16263512.
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    154. Hertz-Picciotto I, Herr CE, Yap PS, Dostál M, Shumway RH, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Srám RJ. Air pollution and lymphocyte phenotype proportions in cord blood. Environ Health Perspect. 2005 Oct; 113(10):1391-8. PMID: 16203253.
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    155. Zhong CY, Zhou YM, Douglas GC, Witschi H, Pinkerton KE. MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats. Carcinogenesis. 2005 Dec; 26(12):2187-95. PMID: 16051644.
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    156. Seymour BW, Peake JL, Pinkerton KE, Kurup VP, Gershwin LJ. Second-hand smoke increases nitric oxide and alters the IgE response in a murine model of allergic aspergillosis. Clin Dev Immunol. 2005 Jun; 12(2):113-24. PMID: 16050142.
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    157. Arredondo J, Chernyavsky AI, Marubio LM, Beaudet AL, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: regulation of gene expression through alpha3beta2 nicotinic receptor in oral epithelial cells. Am J Pathol. 2005 Feb; 166(2):597-613. PMID: 15681842.
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    158. Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma SJ, Hammock BD. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2186-91. PMID: 15684051.
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    159. Wiedeman JA, Kaul R, Heuer LS, Thao NN, Pinkerton KE, Wenman WM. Tobacco smoke induces persistent infection of Chlamydophila pneumoniae in HEp-2 cells. Microb Pathog. 2004 Sep; 37(3):141-8. PMID: 15351037.
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    160. Anderson KL, Pinkerton KE, Uyeminami D, Simons CT, Carstens MI, Carstens E. Antinociception induced by chronic exposure of rats to cigarette smoke. Neurosci Lett. 2004 Aug 05; 366(1):86-91. PMID: 15265596.
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    161. Witschi H, Espiritu I, Uyeminami D, Pinkerton KE, Raabe OG. Chemoprevention of tobacco smoke-induced lung cancer: what animal studies tell us. Chest. 2004 May; 125(5 Suppl):128S. PMID: 15136461.
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    162. Larson SD, Plopper CG, Baker G, Tarkington BK, Decile KC, Pinkerton K, Mansoor JK, Hyde DM, Schelegle ES. Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L286-95. PMID: 15064227.
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    163. Murin S, Pinkerton KE, Hubbard NE, Erickson K. The effect of cigarette smoke exposure on pulmonary metastatic disease in a murine model of metastatic breast cancer. Chest. 2004 Apr; 125(4):1467-71. PMID: 15078760.
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    164. Last JA, Ward R, Temple L, Pinkerton KE, Kenyon NJ. Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. Inhal Toxicol. 2004 Feb; 16(2):93-102. PMID: 15204782.
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    165. Witschi H, Espiritu I, Uyeminami D, Suffia M, Pinkerton KE. Lung tumor response in strain a mice exposed to tobacco smoke: some dose-effect relationships. Inhal Toxicol. 2004 Jan; 16(1):27-32. PMID: 14744662.
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    166. Pinkerton KE, Zhou YM, Teague SV, Peake JL, Walther RC, Kennedy IM, Leppert VJ, Aust AE. Reduced lung cell proliferation following short-term exposure to ultrafine soot and iron particles in neonatal rats: key to impaired lung growth? Inhal Toxicol. 2004; 16 Suppl 1:73-81. PMID: 15204795.
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    167. Joad JP, Munch PA, Bric JM, Evans SJ, Pinkerton KE, Chen CY, Bonham AC. Passive smoke effects on cough and airways in young guinea pigs: role of brainstem substance P. Am J Respir Crit Care Med. 2004 Feb 15; 169(4):499-504. PMID: 14644932.
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    168. Schelegle ES, Miller LA, Gershwin LJ, Fanucchi MV, Van Winkle LS, Gerriets JE, Walby WF, Mitchell V, Tarkington BK, Wong VJ, Baker GL, Pantle LM, Joad JP, Pinkerton KE, Wu R, Evans MJ, Hyde DM, Plopper CG. Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicol Appl Pharmacol. 2003 Aug 15; 191(1):74-85. PMID: 12915105.
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    169. Zhou YM, Zhong CY, Kennedy IM, Pinkerton KE. Pulmonary responses of acute exposure to ultrafine iron particles in healthy adult rats. Environ Toxicol. 2003 Aug; 18(4):227-35. PMID: 12900941.
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    170. Zhou YM, Zhong CY, Kennedy IM, Leppert VJ, Pinkerton KE. Oxidative stress and NFkappaB activation in the lungs of rats: a synergistic interaction between soot and iron particles. Toxicol Appl Pharmacol. 2003 Jul 15; 190(2):157-69. PMID: 12878045.
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    171. Smith KR, Kim S, Recendez JJ, Teague SV, Ménache MG, Grubbs DE, Sioutas C, Pinkerton KE. Airborne particles of the california central valley alter the lungs of healthy adult rats. Environ Health Perspect. 2003 Jun; 111(7):902-8; discussion A408-9. PMID: 12782490.
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    172. Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol. 2003 Mar; 10(1):35-42. PMID: 14575156.
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    173. Smith KR, Uyeminami DL, Kodavanti UP, Crapo JD, Chang LY, Pinkerton KE. Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant. Free Radic Biol Med. 2002 Oct 15; 33(8):1106-14. PMID: 12374622.
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    174. Mullick AE, McDonald JM, Melkonian G, Talbot P, Pinkerton KE, Rutledge JC. Reactive carbonyls from tobacco smoke increase arterial endothelial layer injury. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H591-7. PMID: 12124206.
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    175. Yu M, Zheng X, Witschi H, Pinkerton KE. The role of interleukin-6 in pulmonary inflammation and injury induced by exposure to environmental air pollutants. Toxicol Sci. 2002 Aug; 68(2):488-97. PMID: 12151646.
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    176. Wignarajah D, Cock ML, Pinkerton KE, Harding R. Influence of intrauterine growth restriction on airway development in fetal and postnatal sheep. Pediatr Res. 2002 Jun; 51(6):681-8. PMID: 12032261.
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    177. Kott KS, Pinkerton KE, Bric JM, Plopper CG, Avadhanam KP, Joad JP. Methacholine responsiveness of proximal and distal airways of monkeys and rats using videomicrometry. J Appl Physiol (1985). 2002 Mar; 92(3):989-96. PMID: 11842031.
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    178. Seymour BW, Friebertshauser KE, Peake JL, Pinkerton KE, Coffman RL, Gershwin LJ. Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. Dev Immunol. 2002 Mar; 9(1):47-54. PMID: 12353662.
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    179. Nadadur SS, Pinkerton KE, Kodavanti UP. Pulmonary gene expression profiles of spontaneously hypertensive rats exposed to environmental tobacco smoke. Chest. 2002 Mar; 121(3 Suppl):83S-84S. PMID: 11893708.
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    180. Slotkin TA, Pinkerton KE, Auman JT, Qiao D, Seidler FJ. Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. Brain Res Dev Brain Res. 2002 Feb 28; 133(2):175-9. PMID: 11882347.
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    181. Warheit DB, Reed KL, Pinkerton KE, Webb TR. Biodegradability of inhaled p-aramid respirable fiber-shaped particulates (RFP): mechanisms of RFP shortening and evidence of reversibility of pulmonary lesions. Toxicol Lett. 2002 Feb 28; 127(1-3):259-67. PMID: 12052666.
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    182. Knight-Lozano CA, Young CG, Burow DL, Hu ZY, Uyeminami D, Pinkerton KE, Ischiropoulos H, Ballinger SW. Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation. 2002 Feb 19; 105(7):849-54. PMID: 11854126.
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    183. Witschi H, Espiritu I, Suffia M, Pinkerton KE. Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents. Carcinogenesis. 2002 Feb; 23(2):289-94. PMID: 11872634.
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    184. Yu M, Pinkerton KE, Witschi H. Short-term exposure to aged and diluted sidestream cigarette smoke enhances ozone-induced lung injury in B6C3F1 mice. Toxicol Sci. 2002 Jan; 65(1):99-106. PMID: 11752689.
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    185. Arredondo J, Nguyen VT, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. A receptor-mediated mechanism of nicotine toxicity in oral keratinocytes. Lab Invest. 2001 Dec; 81(12):1653-68. PMID: 11742036.
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    186. Slotkin TA, Pinkerton KE, Garofolo MC, Auman JT, McCook EC, Seidler FJ. Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats. Brain Res. 2001 Apr 13; 898(1):73-81. PMID: 11292450.
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    187. Van Winkle LS, Evans MJ, Brown CD, Willits NH, Pinkerton KE, Plopper CG. Prior exposure to aged and diluted sidestream cigarette smoke impairs bronchiolar injury and repair. Toxicol Sci. 2001 Mar; 60(1):152-64. PMID: 11222882.
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    188. Schelegle ES, Gershwin LJ, Miller LA, Fanucchi MV, Van Winkle LS, Gerriets JP, Walby WF, Omlor AM, Buckpitt AR, Tarkington BK, Wong VJ, Joad JP, Pinkerton KB, Wu R, Evans MJ, Hyde DM, Plopper CG. Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae). Am J Pathol. 2001 Jan; 158(1):333-41. PMID: 11141508.
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    189. Slotkin TA, Pinkerton KE, Seidler FJ. Perinatal exposure to environmental tobacco smoke alters cell signaling in a primate model: autonomic receptors and the control of adenylyl cyclase activity in heart and lung. Brain Res Dev Brain Res. 2000 Nov 30; 124(1-2):53-8. PMID: 11113511.
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    190. Pinkerton KE, Green FH, Saiki C, Vallyathan V, Plopper CG, Gopal V, Hung D, Bahne EB, Lin SS, Ménache MG, Schenker MB. Distribution of particulate matter and tissue remodeling in the human lung. Environ Health Perspect. 2000 Nov; 108(11):1063-9. PMID: 11102298.
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    191. Pinkerton KE, Joad JP. The mammalian respiratory system and critical windows of exposure for children's health. Environ Health Perspect. 2000 Jun; 108 Suppl 3:457-62. PMID: 10852845.
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    192. Dietert RR, Etzel RA, Chen D, Halonen M, Holladay SD, Jarabek AM, Landreth K, Peden DB, Pinkerton K, Smialowicz RJ, Zoetis T. Workshop to identify critical windows of exposure for children's health: immune and respiratory systems work group summary. Environ Health Perspect. 2000 Jun; 108 Suppl 3:483-90. PMID: 10852848.
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    193. Pinkerton KE, Ikegami M, Dillard LM, Jobe AH. Surfactant treatment effects on lung structure and type II cells of preterm ventilated lambs. Biol Neonate. 2000 May; 77(4):243-52. PMID: 10828576.
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    194. Weller BL, Witschi H, Pinkerton KE. Quantitation and localization of pulmonary manganese superoxide dismutase and tumor necrosis factor alpha following exposure to ozone and nitrogen dioxide. Toxicol Sci. 2000 Apr; 54(2):452-61. PMID: 10774828.
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    195. Rider ED, Ikegami M, Pinkerton KE, Peake JL, Jobe AH. Lysosomes from rabbit type II cells catabolize surfactant lipids. Am J Physiol Lung Cell Mol Physiol. 2000 Jan; 278(1):L68-74. PMID: 10645892.
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    196. Peake JL, Reynolds SD, Stripp BR, Stephens KE, Pinkerton KE. Alteration of pulmonary neuroendocrine cells during epithelial repair of naphthalene-induced airway injury. Am J Pathol. 2000 Jan; 156(1):279-86. PMID: 10623676.
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    197. Lee CZ, Royce FH, Denison MS, Pinkerton KE. Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases. J Biochem Mol Toxicol. 2000; 14(3):121-30. PMID: 10711627.
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    198. Witschi H, Espiritu I, Pinkerton KE, Murphy K, Maronpot RR. Ozone carcinogenesis revisited. Toxicol Sci. 1999 Dec; 52(2):162-7. PMID: 10630568.
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    199. Hyde DM, Miller LA, McDonald RJ, Stovall MY, Wong V, Pinkerton KE, Wegner CD, Rothlein R, Plopper CG. Neutrophils enhance clearance of necrotic epithelial cells in ozone-induced lung injury in rhesus monkeys. Am J Physiol. 1999 12; 277(6):L1190-8. PMID: 10600890.
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    200. Rice RH, Wong VJ, Williams ML, Price VH, Hohl D, Sundberg JP, Pinkerton KE. Hair shaft defects visualized after detergent extraction. Exp Dermatol. 1999 Aug; 8(4):308-10. PMID: 10439239.
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    201. Willet KE, McMenamin P, Pinkerton KE, Ikegami M, Jobe AH, Gurrin L, Sly PD. Lung morphometry and collagen and elastin content: changes during normal development and after prenatal hormone exposure in sheep. Pediatr Res. 1999 May; 45(5 Pt 1):615-25. PMID: 10231854.
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    202. Joad JP, Bric JM, Peake JL, Pinkerton KE. Perinatal exposure to aged and diluted sidestream cigarette smoke produces airway hyperresponsiveness in older rats. Toxicol Appl Pharmacol. 1999 Mar 15; 155(3):253-60. PMID: 10079211.
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    203. Farman CA, Watkins K, van Hoozen B, Last JA, Witschi H, Pinkerton KE. Centriacinar remodeling and sustained procollagen gene expression after exposure to ozone and nitrogen dioxide. Am J Respir Cell Mol Biol. 1999 Feb; 20(2):303-11. PMID: 9922222.
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    204. Rice RH, Wong VJ, Pinkerton KE, Sundberg JP. Cross-linked features of mouse pelage hair resistant to detergent extraction. Anat Rec. 1999 02 01; 254(2):231-7. PMID: 9972808.
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    205. Madl AK, Wilson DW, Segall HJ, Pinkerton KE. Alteration in lung particle translocation, macrophage function, and microfilament arrangement in monocrotaline-treated rats. Toxicol Appl Pharmacol. 1998 Nov; 153(1):28-38. PMID: 9875297.
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    206. Ji CM, Royce FH, Truong U, Plopper CG, Singh G, Pinkerton KE. Maternal exposure to environmental tobacco smoke alters Clara cell secretory protein expression in fetal rat lung. Am J Physiol. 1998 11; 275(5):L870-6. PMID: 9815103.
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    207. Pinkerton KE, Weller BL, Ménache MG, Plopper CG. Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part XIII. A comparison of changes in the tracheobronchial epithelium and pulmonary acinus in male rats at 3 and 20 months. Res Rep Health Eff Inst. 1998 Jun; (65):1-32; discussion 33-7. PMID: 9697229.
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    208. Lee C, Watt KC, Chang AM, Plopper CG, Buckpitt AR, Pinkerton KE. Site-selective differences in cytochrome P450 isoform activities. Comparison of expression in rat and rhesus monkey lung and induction in rats. Drug Metab Dispos. 1998 May; 26(5):396-400. PMID: 9571220.
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    209. Seymour BW, Pinkerton KE, Friebertshauser KE, Coffman RL, Gershwin LJ. Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy. J Immunol. 1997 Dec 15; 159(12):6169-75. PMID: 9550419.
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    210. Weller BL, Crapo JD, Slot J, Posthuma G, Plopper CG, Pinkerton KE. Site- and cell-specific alteration of lung copper/zinc and manganese superoxide dismutases by chronic ozone exposure. Am J Respir Cell Mol Biol. 1997 Nov; 17(5):552-60. PMID: 9374106.
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    211. Witschi H, Espiritu I, Maronpot RR, Pinkerton KE, Jones AD. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis. 1997 Nov; 18(11):2035-42. PMID: 9395199.
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    212. Pinkerton KE, Willet KE, Peake JL, Sly PD, Jobe AH, Ikegami M. Prenatal glucocorticoid and T4 effects on lung morphology in preterm lambs. Am J Respir Crit Care Med. 1997 Aug; 156(2 Pt 1):624-30. PMID: 9279249.
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    213. Witschi H, Espiritu I, Pinkerton KE. Pulmonary cell kinetics and morphometry after ozone exposure: day versus night and dose response in rats. Am J Physiol. 1997 Jun; 272(6 Pt 1):L1152-60. PMID: 9227517.
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    214. Matsumura F, Enan E, Dunlap DY, Pinkerton KE, Peake J. Altered in vivo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C-SRC deficient mice. Biochem Pharmacol. 1997 May 15; 53(10):1397-404. PMID: 9260865.
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    215. Witschi H, Espiritu I, Peake JL, Wu K, Maronpot RR, Pinkerton KE. The carcinogenicity of environmental tobacco smoke. Carcinogenesis. 1997 Mar; 18(3):575-86. PMID: 9067559.
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    216. Stevens TP, McBride JT, Peake JL, Pinkerton KE, Stripp BR. Cell proliferation contributes to PNEC hyperplasia after acute airway injury. Am J Physiol. 1997 Mar; 272(3 Pt 1):L486-93. PMID: 9124606.
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    217. Avadhanam KP, Plopper CG, Pinkerton KE. Mapping the distribution of neuroepithelial bodies of the rat lung. A whole-mount immunohistochemical approach. Am J Pathol. 1997 Mar; 150(3):851-9. PMID: 9060823.
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    218. Last JA, Pinkerton KE. Chronic exposure of rats to ozone and sulfuric acid aerosol: biochemical and structural responses. Toxicology. 1997 Jan 15; 116(1-3):133-46. PMID: 9020514.
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    219. Witschi H, Joad JP, Pinkerton KE. The toxicology of environmental tobacco smoke. Annu Rev Pharmacol Toxicol. 1997; 37:29-52. PMID: 9131245.
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    220. Rice RH, Wong VJ, Price VH, Hohl D, Pinkerton KE. Cuticle cell defects in lamellar ichthyosis hair and anomalous hair shaft syndromes visualized after detergent extraction. Anat Rec. 1996 Dec; 246(4):433-40. PMID: 8955782.
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    221. Roberts KA, Rezai AA, Pinkerton KE, Rutledge JC. Effect of environmental tobacco smoke on LDL accumulation in the artery wall. Circulation. 1996 Nov 01; 94(9):2248-53. PMID: 8901679.
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    222. Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE. Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke. Toxicol Appl Pharmacol. 1996 Nov; 141(1):76-83. PMID: 8917678.
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    223. Joad JP, Avadhanam KP, Watt KC, Kott KS, Bric JM, Pinkerton KE. Effects of extended sidestream smoke exposure on components of the C-fiber axon reflex. Toxicology. 1996 Sep 02; 112(3):195-203. PMID: 8845040.
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    224. Gospe SM, Zhou SS, Pinkerton KE. Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development. Pediatr Res. 1996 Mar; 39(3):494-8. PMID: 8929871.
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    225. Enan E, Pinkerton KE, Peake J, Matsumura F. Deltamethrin-induced thymus atrophy in male Balb/c mice. Biochem Pharmacol. 1996 Feb 23; 51(4):447-54. PMID: 8619889.
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    226. Duan X, Buckpitt AR, Pinkerton KE, Ji C, Plopper CG. Ozone-induced alterations in glutathione in lung subcompartments of rats and monkeys. Am J Respir Cell Mol Biol. 1996 Jan; 14(1):70-5. PMID: 8534488.
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    227. Gebremichael A, Chang AM, Buckpitt AR, Plopper CG, Pinkerton KE. Postnatal development of cytochrome P4501A1 and 2B1 in rat lung and liver: effect of aged and diluted sidestream cigarette smoke. Toxicol Appl Pharmacol. 1995 Dec; 135(2):246-53. PMID: 8545834.
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    228. Lee C, Rajini P, Pinkerton KE, Witschi H. Correlation between cumulative labeling indices measured in the terminal bronchioles and in the centriacinar region in the lungs of rats exposed to oxidant air pollutants. Toxicol Lett. 1995 Oct; 80(1-3):25-8. PMID: 7482587.
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    229. Ji CM, Cardoso WV, Gebremichael A, Philpot RM, Buckpitt AR, Plopper CG, Pinkerton KE. Pulmonary cytochrome P-450 monooxygenase system and Clara cell differentiation in rats. Am J Physiol. 1995 Sep; 269(3 Pt 1):L394-402. PMID: 7573474.
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    230. Ji CM, Plopper CG, Pinkerton KE. Clara cell heterogeneity in differentiation: correlation with proliferation, ultrastructural composition, and cell position in the rat bronchiole. Am J Respir Cell Mol Biol. 1995 Aug; 13(2):144-51. PMID: 7626284.
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    231. Witschi H, Oreffo VI, Pinkerton KE. Six-month exposure of strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data. Fundam Appl Toxicol. 1995 Jun; 26(1):32-40. PMID: 7657060.
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    232. Joad JP, Ji C, Kott KS, Bric JM, Pinkerton KE. In utero and postnatal effects of sidestream cigarette smoke exposure on lung function, hyperresponsiveness, and neuroendocrine cells in rats. Toxicol Appl Pharmacol. 1995 May; 132(1):63-71. PMID: 7747286.
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    233. Catalano PJ, Chang LY, Harkema JR, Kaden DA, Last JA, Mellick PW, Parks WC, Pinkerton KE, Radhakrishnamurthy B, Ryan LM. Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part XI: Integrative Summary. Res Rep Health Eff Inst. 1995 Apr; (65 Pt 11):1-54; discussion 55-85. PMID: 7598833.
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    234. Joad JP, Bric JM, Pinkerton KE. Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs. Toxicol Appl Pharmacol. 1995 Apr; 131(2):289-96. PMID: 7536361.
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    235. Pinkerton KE, Ménache MG, Plopper CG. Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part IX: Changes in the tracheobronchial epithelium, pulmonary acinus, and lung antioxidant enzyme activity. Res Rep Health Eff Inst. 1995 Mar; (65 Pt 8-9):41-98; discussion 99-110. PMID: 7619334.
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    236. Witschi H, Pinkerton KE, Coggins CR, Penn A, Gori GB. Environmental tobacco smoke: experimental facts and societal issues. Fundam Appl Toxicol. 1995 Jan; 24(1):3-12. PMID: 7713341.
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    237. Pinkerton KE, Lewis JF, Rider ED, Peake J, Chen W, Madl AK, Luu RH, Ikegami M, Jobe AH. Lung parenchyma and type II cell morphometrics: effect of surfactant treatment on preterm ventilated lamb lungs. J Appl Physiol (1985). 1994 Oct; 77(4):1953-60. PMID: 7836223.
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    238. Ji CM, Plopper CG, Witschi HP, Pinkerton KE. Exposure to sidestream cigarette smoke alters bronchiolar epithelial cell differentiation in the postnatal rat lung. Am J Respir Cell Mol Biol. 1994 Sep; 11(3):312-20. PMID: 8086168.
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    239. Plopper CG, Duan X, Buckpitt AR, Pinkerton KE. Dose-dependent tolerance to ozone. IV. Site-specific elevation in antioxidant enzymes in the lungs of rats exposed for 90 days or 20 months. Toxicol Appl Pharmacol. 1994 Jul; 127(1):124-31. PMID: 8048044.
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    240. Armstrong LC, Watkins K, Pinkerton KE, Last JA. Collagen mRNA content and distribution in the lungs of rats exposed to ozone. Am J Respir Cell Mol Biol. 1994 Jul; 11(1):25-34. PMID: 8018336.
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    241. Rice RH, Wong VJ, Pinkerton KE. Ultrastructural visualization of cross-linked protein features in epidermal appendages. J Cell Sci. 1994 Jul; 107 ( Pt 7):1985-92. PMID: 7983163.
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    242. Dodge DE, Rucker RB, Pinkerton KE, Haselton CJ, Plopper CG. Dose-dependent tolerance to ozone. III. Elevation of intracellular Clara cell 10-kDa protein in central acini of rats exposed for 20 months. Toxicol Appl Pharmacol. 1994 Jul; 127(1):109-23. PMID: 8048043.
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    243. Ohashi T, Pinkerton K, Ikegami M, Jobe AH. Changes in alveolar surface area, surfactant protein A, and saturated phosphatidylcholine with postnatal rat lung growth. Pediatr Res. 1994 Jun; 35(6):685-9. PMID: 7936819.
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    244. Rajini P, Last JA, Pinkerton KE, Hendrickx AG, Witschi H. Decreased fetal weights in rats exposed to sidestream cigarette smoke. Fundam Appl Toxicol. 1994 Apr; 22(3):400-4. PMID: 8050635.
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    245. Plopper CG, Chu FP, Haselton CJ, Peake J, Wu J, Pinkerton KE. Dose-dependent tolerance to ozone. I. Tracheobronchial epithelial reorganization in rats after 20 months' exposure. Am J Pathol. 1994 Feb; 144(2):404-20. PMID: 8311121.
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    246. Pinkerton KE, Gallen JT, Mercer RR, Wong VC, Plopper CG, Tarkington BK. Aerosolized fluorescent microspheres detected in the lung using confocal scanning laser microscopy. Microsc Res Tech. 1993 Dec 01; 26(5):437-43. PMID: 8286789.
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    247. Joad JP, Pinkerton KE, Bric JM. Effects of sidestream smoke exposure and age on pulmonary function and airway reactivity in developing rats. Pediatr Pulmonol. 1993 Nov; 16(5):281-8. PMID: 8255632.
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    248. Last JA, Gelzleichter TR, Pinkerton KE, Walker RM, Witschi H. A new model of progressive pulmonary fibrosis in rats. Am Rev Respir Dis. 1993 Aug; 148(2):487-94. PMID: 8342914.
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    249. Cardoso WV, Stewart LG, Pinkerton KE, Ji C, Hook GE, Singh G, Katyal SL, Thurlbeck WM, Plopper CG. Secretory product expression during Clara cell differentiation in the rabbit and rat. Am J Physiol. 1993 Jun; 264(6 Pt 1):L543-52. PMID: 8333547.
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    250. Pinkerton KE, Dodge DE, Cederdahl-Demmler J, Wong VJ, Peake J, Haselton CJ, Mellick PW, Singh G, Plopper CG. Differentiated bronchiolar epithelium in alveolar ducts of rats exposed to ozone for 20 months. Am J Pathol. 1993 Mar; 142(3):947-56. PMID: 8456949.
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    251. Pinkerton KE, Lewis J, Mulder AM, Ikegami M, Jobe AH. Surfactant treatment effects on alveolar type II cell morphology in rabbit lungs. J Appl Physiol (1985). 1993 Mar; 74(3):1240-7. PMID: 8482664.
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    252. Pinkerton KE, Mercer RR, Plopper CG, Crapo JD. Distribution of injury and microdosimetry of ozone in the ventilatory unit of the rat. J Appl Physiol (1985). 1992 Sep; 73(3):817-24. PMID: 1400043.
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    253. Hyde DM, Hubbard WC, Wong V, Wu R, Pinkerton K, Plopper CG. Ozone-induced acute tracheobronchial epithelial injury: relationship to granulocyte emigration in the lung. Am J Respir Cell Mol Biol. 1992 May; 6(5):481-97. PMID: 1581072.
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    254. Plopper CG, St George JA, Read LC, Nishio SJ, Weir AJ, Edwards L, Tarantal AF, Pinkerton KE, Merritt TA, Whitsett JA. Acceleration of alveolar type II cell differentiation in fetal rhesus monkey lung by administration of EGF. Am J Physiol. 1992 Mar; 262(3 Pt 1):L313-21. PMID: 1550255.
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    255. Plopper C, St George J, Cardoso W, Wu R, Pinkerton K, Buckpitt A. Development of airway epithelium. Patterns of expression for markers of differentiation. Chest. 1992 Mar; 101(3 Suppl):2S-5S. PMID: 1371732.
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    256. Rider ED, Pinkerton KE, Jobe AH. Characterization of rabbit lung lysosomes and their role in surfactant dipalmitoylphosphatidylcholine catabolism. J Biol Chem. 1991 Nov 25; 266(33):22522-8. PMID: 1939269.
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    257. Chang LY, Mercer RR, Pinkerton KE, Crapo JD. Quantifying lung structure. Experimental design and biologic variation in various models of lung injury. Am Rev Respir Dis. 1991 Mar; 143(3):625-34. PMID: 2001076.
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    258. Pinkerton KE, Young SL, Fram EK, Crapo JD. Alveolar type II cell responses to chronic inhalation of chrysotile asbestos in rats. Am J Respir Cell Mol Biol. 1990 Dec; 3(6):543-52. PMID: 2174678.
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    259. Pinkerton KE, Brody AR, Miller FJ, Crapo JD. Exposure to low levels of ozone results in enhanced pulmonary retention of inhaled asbestos fibers. Am Rev Respir Dis. 1989 Oct; 140(4):1075-81. PMID: 2529800.
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    260. Pinkerton KE, Kendall JZ, Randall GC, Chechowitz MA, Hyde DM, Plopper CG. Hypophysectomy and porcine fetal lung development. Am J Respir Cell Mol Biol. 1989 Oct; 1(4):319-28. PMID: 2624765.
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    261. Miller BE, Chapin RE, Pinkerton KE, Gilmore LB, Maronpot RR, Hook GE. Quantitation of silica-induced type II cell hyperplasia by using alkaline phosphatase histochemistry in glycol methacrylate embedded lung. Exp Lung Res. 1987; 12(2):135-48. PMID: 3032599.
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    262. Pinkerton KE, Plopper CG, Mercer RR, Roggli VL, Patra AL, Brody AR, Crapo JD. Airway branching patterns influence asbestos fiber location and the extent of tissue injury in the pulmonary parenchyma. Lab Invest. 1986 Dec; 55(6):688-95. PMID: 3784538.
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    263. Pinkerton KE, Pratt PC, Brody AR, Crapo JD. Fiber localization and its relationship to lung reaction in rats after chronic inhalation of chrysotile asbestos. Am J Pathol. 1984 Dec; 117(3):484-98. PMID: 6095671.
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    264. Crapo JD, Young SL, Fram EK, Pinkerton KE, Barry BE, Crapo RO. Morphometric characteristics of cells in the alveolar region of mammalian lungs. Am Rev Respir Dis. 1983 Aug; 128(2 Pt 2):S42-6. PMID: 6881707.
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    265. Pinkerton KE, Brody AR, McLaurin DA, Adkins B, O'Connor RW, Pratt PC, Crapo JD. Characterization of three types of chrysotile asbestos after aerosolization. Environ Res. 1983 Jun; 31(1):32-53. PMID: 6303775.
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    266. Pinkerton KE, Barry BE, O'Neil JJ, Raub JA, Pratt PC, Crapo JD. Morphologic changes in the lung during the lifespan of Fischer 344 rats. Am J Anat. 1982 Jun; 164(2):155-74. PMID: 7102577.
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