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Kent E Pinkerton

TitleProfessor
InstitutionUniversity of California Davis
DepartmentPediatric Pulmonary
Address103 Center for Health and the Environment
CA 95616
Phone530-752-8334
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    Collapse Research 
    Collapse Research Activities and Funding
    Respiratory and Ocular Toxicity of Inhaled Nanomaterials
    NIH/NIEHS U01ES027288Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Agriculture and Climate Change Impacts on Workers' Health and Safety
    CDC/NIOSH U01OH010969Sep 1, 2016 - Aug 31, 2019
    Role: Principal Investigator
    Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology
    NIH/NIEHS U01ES020127Sep 27, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Respiratory Health Effects of Global Climate Change Workshop
    NIH/NIEHS R13ES019427May 10, 2010 - Apr 30, 2011
    Role: Principal Investigator
    Novel approaches to evaluate carbon nanotube health impacts
    NIH/NIEHS RC1ES018232Sep 25, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Environmental Influences on Perinatal Lung Development
    NIH/NIEHS R01ES011634May 1, 2002 - Feb 28, 2008
    Role: Principal Investigator
    Reducing occupational exposure to zoonotic pathogens in California dairy farm workers
    CDC/NIOSH U54OH007550Sep 30, 2001 - Sep 29, 2021
    Role: Co-Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R29ES004338Jul 1, 1986 - Feb 28, 1992
    Role: Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R23ES004338Jul 1, 1986 - Dec 31, 1988
    Role: Principal Investigator
    LUNG EPITHELIUM AND INTERSTITIAL ASBESTOS ACCUMULATION
    NIH/NIEHS R23ES003634Jan 1, 1986 - Jun 30, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Xu J, Qiu X, Liang Z, Smiley-Jewell S, Lu F, Yu M, Pinkerton KE, Zhao D, Shi B. Exposure to tobacco smoke increases bone loss in spontaneously hypertensive rats. Inhal Toxicol. 2018 Sep 26; 1-10. PMID: 30257116.
      View in: PubMed
    2. Castañeda AR, Vogel CFA, Bein KJ, Hughes HK, Smiley-Jewell S, Pinkerton KE. Ambient particulate matter enhances the pulmonary allergic immune response to house dust mite in a BALB/c mouse model by augmenting Th2- and Th17-immune responses. Physiol Rep. 2018 Sep; 6(18):e13827. PMID: 30230272.
      View in: PubMed
    3. Pinkerton KE, Poindexter ME. Harmful Interruptions: Impact of Smoking Patterns on Tumorigenesis and Emphysema. Am J Respir Cell Mol Biol. 2018 Jun 04. PMID: 29864376.
      View in: PubMed
    4. Castañeda AR, Pinkerton KE, Bein KJ, Magaña-Méndez A, Yang HT, Ashwood P, Vogel CFA. Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization. Toxicol Lett. 2018 Apr 22; 292:85-96. PMID: 29689377.
      View in: PubMed
    5. Miller LA, Royer CM, Pinkerton KE, Schelegle ES. Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. ILAR J. 2017 Dec 01; 58(2):269-280. PMID: 29216343.
      View in: PubMed
    6. Hopkins LE, Laing EA, Peake JL, Uyeminami D, Mack SM, Li X, Smiley-Jewell S, Pinkerton KE. Repeated Iron-Soot Exposure and Nose-to-brain Transport of Inhaled Ultrafine Particles. Toxicol Pathol. 2018 Jan; 46(1):75-84. PMID: 28914166.
      View in: PubMed
    7. Ferrini M, Carvalho S, Cho YH, Postma B, Miranda Marques L, Pinkerton K, Roberts K, Jaffar Z. Prenatal tobacco smoke exposure predisposes offspring mice to exacerbated allergic airway inflammation associated with altered innate effector function. Part Fibre Toxicol. 2017 Aug 22; 14(1):30. PMID: 28830530.
      View in: PubMed
    8. Cole E, Brown TA, Pinkerton KE, Postma B, Malany K, Yang M, Kim YJ, Hamilton RF, Holian A, Cho YH. Perinatal exposure to environmental tobacco smoke is associated with changes in DNA methylation that precede the adult onset of lung disease in a mouse model. Inhal Toxicol. 2017 Aug; 29(10):435-442. PMID: 29124997.
      View in: PubMed
    9. Sun X, Wei H, Young DE, Bein KJ, Smiley-Jewell SM, Zhang Q, Fulgar CCB, Castañeda AR, Pham AK, Li W, Pinkerton KE. Differential pulmonary effects of wintertime California and China particulate matter in healthy young mice. Toxicol Lett. 2017 Aug 15; 278:1-8. PMID: 28698096.
      View in: PubMed
    10. Christensen S, Jaffar Z, Cole E, Porter V, Ferrini M, Postma B, Pinkerton KE, Yang M, Kim YJ, Montrose L, Roberts K, Holian A, Cho YH. Prenatal environmental tobacco smoke exposure increases allergic asthma risk with methylation changes in mice. Environ Mol Mutagen. 2017 07; 58(6):423-433. PMID: 28543436.
      View in: PubMed
    11. Castañeda AR, Bein KJ, Smiley-Jewell S, Pinkerton KE. Fine particulate matter (PM2.5) enhances allergic sensitization in BALB/c mice. J Toxicol Environ Health A. 2017; 80(4):197-207. PMID: 28494199.
      View in: PubMed
    12. Shen YH, Pham AK, Davis B, Smiley-Jewell S, Wang L, Kodavanti UP, Takeuchi M, Tancredi DJ, Pinkerton KE. Sex and strain-based inflammatory response to repeated tobacco smoke exposure in spontaneously hypertensive and Wistar Kyoto rats. Inhal Toxicol. 2016 12; 28(14):677-685. PMID: 27829308.
      View in: PubMed
    13. Barupal DK, Pinkerton KE, Hood C, Kind T, Fiehn O. Environmental Tobacco Smoke Alters Metabolic Systems in Adult Rats. Chem Res Toxicol. 2016 11 21; 29(11):1818-1827. PMID: 27788581.
      View in: PubMed
    14. Hoang LL, Nguyen YP, Aspeé R, Bolton SJ, Shen YH, Wang L, Kenyon NJ, Smiley-Jewell S, Pinkerton KE. Temporal and Spatial Expression of Transforming Growth Factor-ß after Airway Remodeling to Tobacco Smoke in Rats. Am J Respir Cell Mol Biol. 2016 06; 54(6):872-81. PMID: 26637070.
      View in: PubMed
    15. Patchin ES, Anderson DS, Silva RM, Uyeminami DL, Scott GM, Guo T, Van Winkle LS, Pinkerton KE. Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain. Environ Health Perspect. 2016 12; 124(12):1870-1875. PMID: 27152509.
      View in: PubMed
    16. Castañeda AR, Pinkerton KE. Investigating the Effects of Particulate Matter on House Dust Mite and Ovalbumin Allergic Airway Inflammation in Mice. Curr Protoc Toxicol. 2016 May 04; 68:18.18.1-18.18.18. PMID: 27145110; PMCID: PMC4988128 [Available on 05/04/17].
    17. Brown TA, Holian A, Pinkerton KE, Lee JW, Cho YH. Early life exposure to environmental tobacco smoke alters immune response to asbestos via a shift in inflammatory phenotype resulting in increased disease development. Inhal Toxicol. 2016 07; 28(8):349-56. PMID: 27138493.
      View in: PubMed
    18. Silva RM, Anderson DS, Peake J, Edwards PC, Patchin ES, Guo T, Gordon T, Chen LC, Sun X, Van Winkle LS, Pinkerton KE. Aerosolized Silver Nanoparticles in the Rat Lung and Pulmonary Responses over Time. Toxicol Pathol. 2016 07; 44(5):673-86. PMID: 27025955; PMCID: PMC4912458 [Available on 07/01/17].
    19. Kurt OK, Zhang J, Pinkerton KE. Pulmonary health effects of air pollution. Curr Opin Pulm Med. 2016 Mar; 22(2):138-43. PMID: 26761628; PMCID: PMC4776742 [Available on 03/01/17].
    20. Liu YX, Karsai A, Anderson DS, Silva RM, Uyeminami DL, Van Winkle LS, Pinkerton KE, Liu GY. Single-Cell Mechanics Provides an Effective Means To Probe in Vivo Interactions between Alveolar Macrophages and Silver Nanoparticles. J Phys Chem B. 2015 Dec 10; 119(49):15118-29. PMID: 26562364.
      View in: PubMed
    21. Lee JW, Jaffar Z, Pinkerton KE, Porter V, Postma B, Ferrini M, Holian A, Roberts K, Cho YH. Alterations in DNA methylation and airway hyperreactivity in response to in utero exposure to environmental tobacco smoke. Inhal Toxicol. 2015; 27(13):724-30. PMID: 26525176; PMCID: PMC4760648 [Available on 11/02/16].
    22. Plummer LE, Carosino CM, Bein KJ, Zhao Y, Willits N, Smiley-Jewell S, Wexler AS, Pinkerton KE. Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley. Atmos Environ (1994). 2015 Oct 01; 119:174-181. PMID: 26568698.
      View in: PubMed
    23. Belafsky PC, Peake J, Smiley-Jewell SM, Verma SP, Dworkin-Valenti J, Pinkerton KE. Soot and house dust mite allergen cause eosinophilic laryngitis in an animal model. Laryngoscope. 2016 Jan; 126(1):108-12. PMID: 26197967.
      View in: PubMed
    24. Nording ML, Yang J, Hoang L, Zamora V, Uyeminami D, Espiritu I, Pinkerton KE, Hammock BD, Luria A. Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. J Metabolomics. 2015 Apr; 1. PMID: 27076918.
      View in: PubMed
    25. Li X, Xue M, Raabe OG, Aaron HL, Eisen EA, Evans JE, Hayes FA, Inaga S, Tagmount A, Takeuchi M, Vulpe C, Zink JI, Risbud SH, Pinkerton KE. Aerosol droplet delivery of mesoporous silica nanoparticles: A strategy for respiratory-based therapeutics. Nanomedicine. 2015 Aug; 11(6):1377-85. PMID: 25819886; PMCID: PMC4494876.
    26. Silva RM, Anderson DS, Franzi LM, Peake JL, Edwards PC, Van Winkle LS, Pinkerton KE. Pulmonary effects of silver nanoparticle size, coating, and dose over time upon intratracheal instillation. Toxicol Sci. 2015 Mar; 144(1):151-62. PMID: 25628415; PMCID: PMC4349140.
    27. Anderson DS, Patchin ES, Silva RM, Uyeminami DL, Sharmah A, Guo T, Das GK, Brown JM, Shannahan J, Gordon T, Chen LC, Pinkerton KE, Van Winkle LS. Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung. Toxicol Sci. 2015 Apr; 144(2):366-81. PMID: 25577195; PMCID: PMC4372666.
    28. Carosino CM, Bein KJ, Plummer LE, Castañeda AR, Zhao Y, Wexler AS, Pinkerton KE. Allergic airway inflammation is differentially exacerbated by daytime and nighttime ultrafine and submicron fine ambient particles: heme oxygenase-1 as an indicator of PM-mediated allergic inflammation. J Toxicol Environ Health A. 2015; 78(4):254-66. PMID: 25679046.
      View in: PubMed
    29. Davidson RA, Anderson DS, Van Winkle LS, Pinkerton KE, Guo T. Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy. J Phys Chem A. 2015 Jan 15; 119(2):281-9. PMID: 25517690.
      View in: PubMed
    30. Hopkins LE, Patchin ES, Chiu PL, Brandenberger C, Smiley-Jewell S, Pinkerton KE. Nose-to-brain transport of aerosolised quantum dots following acute exposure. Nanotoxicology. 2014 Dec; 8(8):885-93. PMID: 24040866; PMCID: PMC3992067.
    31. Van Winkle LS, Bein K, Anderson D, Pinkerton KE, Tablin F, Wilson D, Wexler AS. Biological dose response to PM2.5: effect of particle extraction method on platelet and lung responses. Toxicol Sci. 2015 Feb; 143(2):349-59. PMID: 25389146; PMCID: PMC4306718.
    32. Silva RM, Xu J, Saiki C, Anderson DS, Franzi LM, Vulpe CD, Gilbert B, Van Winkle LS, Pinkerton KE. Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation. Part Fibre Toxicol. 2014 Oct 08; 11:52. PMID: 25292367; PMCID: PMC4198797.
    33. Anderson DS, Silva RM, Lee D, Edwards PC, Sharmah A, Guo T, Pinkerton KE, Van Winkle LS. Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition. Nanotoxicology. 2015; 9(5):591-602. PMID: 25231189; PMCID: PMC4364933.
    34. Silva RM, Doudrick K, Franzi LM, TeeSy C, Anderson DS, Wu Z, Mitra S, Vu V, Dutrow G, Evans JE, Westerhoff P, Van Winkle LS, Raabe OG, Pinkerton KE. Instillation versus inhalation of multiwalled carbon nanotubes: exposure-related health effects, clearance, and the role of particle characteristics. ACS Nano. 2014 Sep 23; 8(9):8911-31. PMID: 25144856; PMCID: PMC4174094.
    35. Madl AK, Plummer LE, Carosino C, Pinkerton KE. Nanoparticles, lung injury, and the role of oxidant stress. Annu Rev Physiol. 2014; 76:447-65. PMID: 24215442; PMCID: PMC4408931.
    36. Wang X, Ji Z, Chang CH, Zhang H, Wang M, Liao YP, Lin S, Meng H, Li R, Sun B, Winkle LV, Pinkerton KE, Zink JI, Xia T, Nel AE. Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small. 2014 Jan 29; 10(2):385-98. PMID: 24039004; PMCID: PMC4001734.
    37. Bonner JC, Silva RM, Taylor AJ, Brown JM, Hilderbrand SC, Castranova V, Porter D, Elder A, Oberdörster G, Harkema JR, Bramble LA, Kavanagh TJ, Botta D, Nel A, Pinkerton KE. Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect. 2013 Jun; 121(6):676-82. PMID: 23649427; PMCID: PMC3672912.
    38. Silva RM, Teesy C, Franzi L, Weir A, Westerhoff P, Evans JE, Pinkerton KE. Biological response to nano-scale titanium dioxide (TiO2): role of particle dose, shape, and retention. J Toxicol Environ Health A. 2013; 76(16):953-72. PMID: 24156719; PMCID: PMC4370163.
    39. Davis BB, Zeki AA, Bratt JM, Wang L, Filosto S, Walby WF, Kenyon NJ, Goldkorn T, Schelegle ES, Pinkerton KE. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. Eur Respir J. 2013 Aug; 42(2):350-61. PMID: 23180589.
      View in: PubMed
    40. Claude JA, Grimm A, Savage HP, Pinkerton KE. Perinatal exposure to environmental tobacco smoke (ETS) enhances susceptibility to viral and secondary bacterial infections. Int J Environ Res Public Health. 2012 Oct 31; 9(11):3954-64. PMID: 23202826; PMCID: PMC3524607.
    41. Berman JD, Fann N, Hollingsworth JW, Pinkerton KE, Rom WN, Szema AM, Breysse PN, White RH, Curriero FC. Health benefits from large-scale ozone reduction in the United States. Environ Health Perspect. 2012 Oct; 120(10):1404-10. PMID: 22809899; PMCID: PMC3491929.
    42. Tell LA, Stephens K, Teague SV, Pinkerton KE, Raabe OG. Study of nebulization delivery of aerosolized fluorescent microspheres to the avian respiratory tract. Avian Dis. 2012 Jun; 56(2):381-6. PMID: 22856198; PMCID: PMC4451201.
    43. Barupal DK, Haldiya PK, Wohlgemuth G, Kind T, Kothari SL, Pinkerton KE, Fiehn O. MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. BMC Bioinformatics. 2012 May 16; 13:99. PMID: 22591066; PMCID: PMC3495401.
    44. Davis BB, Shen YH, Tancredi DJ, Flores V, Davis RP, Pinkerton KE. Leukocytes are recruited through the bronchial circulation to the lung in a spontaneously hypertensive rat model of COPD. PLoS One. 2012; 7(3):e33304. PMID: 22457750; PMCID: PMC3310053.
    45. Zhao X, Bu DX, Hayfron K, Pinkerton KE, Bevins CL, Lichtman A, Wiedeman J. A combination of secondhand cigarette smoke and Chlamydia pneumoniae accelerates atherosclerosis. Atherosclerosis. 2012 May; 222(1):59-66. PMID: 22410122.
      View in: PubMed
    46. Plummer LE, Ham W, Kleeman MJ, Wexler A, Pinkerton KE. Influence of season and location on pulmonary response to California's San Joaquin Valley airborne particulate matter. J Toxicol Environ Health A. 2012; 75(5):253-71. PMID: 22409489.
      View in: PubMed
    47. Balmes J, Pinkerton K. Clearing the air. Am J Respir Crit Care Med. 2012 Jan 01; 185(1):1-2. PMID: 22210780.
      View in: PubMed
    48. Wang L, Yang J, Guo L, Uyeminami D, Dong H, Hammock BD, Pinkerton KE. Use of a soluble epoxide hydrolase inhibitor in smoke-induced chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2012 May; 46(5):614-22. PMID: 22180869; PMCID: PMC3359909.
    49. Davis BB, Liu JY, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochem Biophys Res Commun. 2011 Jul 08; 410(3):494-500. PMID: 21683067; PMCID: PMC3166856.
    50. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Distinct tachykinin NK(1) receptor function in primate nucleus tractus solitarius neurons is dysregulated after second-hand tobacco smoke exposure. Br J Pharmacol. 2011 Jun; 163(4):782-91. PMID: 21323902; PMCID: PMC3111680.
    51. Herr CE, Ghosh R, Dostal M, Skokanova V, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Yap PS, Frost JD, Sram R, Hertz-Picciotto I. Exposure to air pollution in critical prenatal time windows and IgE levels in newborns. Pediatr Allergy Immunol. 2011 Feb; 22(1 Pt 1):75-84. PMID: 20609135.
      View in: PubMed
    52. Harrison CM, Pompilius M, Pinkerton KE, Ballinger SW. Mitochondrial oxidative stress significantly influences atherogenic risk and cytokine-induced oxidant production. Environ Health Perspect. 2011 May; 119(5):676-81. PMID: 21169125; PMCID: PMC3094420.
    53. Wang L, Green FH, Smiley-Jewell SM, Pinkerton KE. Susceptibility of the aging lung to environmental injury. Semin Respir Crit Care Med. 2010 Oct; 31(5):539-53. PMID: 20941655; PMCID: PMC4371868.
    54. Herr CE, Dostal M, Ghosh R, Ashwood P, Lipsett M, Pinkerton KE, Sram R, Hertz-Picciotto I. Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths. Environ Health. 2010 Aug 02; 9:46. PMID: 20678227; PMCID: PMC2927516.
    55. Filosto S, Castillo S, Danielson A, Franzi L, Khan E, Kenyon N, Last J, Pinkerton K, Tuder R, Goldkorn T. Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):350-60. PMID: 20448054; PMCID: PMC3095936.
    56. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs. Eur J Neurosci. 2010 Feb; 31(4):673-84. PMID: 20384811.
      View in: PubMed
    57. Zhong CY, Zhou YM, Smith KR, Kennedy IM, Chen CY, Aust AE, Pinkerton KE. Oxidative injury in the lungs of neonatal rats following short-term exposure to ultrafine iron and soot particles. J Toxicol Environ Health A. 2010; 73(12):837-47. PMID: 20391124.
      View in: PubMed
    58. Ishida T, Hirono Y, Yoshikawa K, Hutei Y, Miyagawa M, Sakaguchi I, Pinkerton KE, Takeuchi M. Inhibition of immunological function mediated DNA damage of alveolar macrophages caused by cigarette smoke in mice. Inhal Toxicol. 2009 Dec; 21(14):1229-35. PMID: 19922407.
      View in: PubMed
    59. Sekizawa S, Joad JP, Pinkerton KE, Bonham AC. Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates. Toxicol Appl Pharmacol. 2010 Jan 15; 242(2):199-208. PMID: 19850058.
      View in: PubMed
    60. Pham H, Bonham AC, Pinkerton KE, Chen CY. Central neuroplasticity and decreased heart rate variability after particulate matter exposure in mice. Environ Health Perspect. 2009 Sep; 117(9):1448-53. PMID: 19750112; PMCID: PMC2737024.
    61. Woodruff PG, Ellwanger A, Solon M, Cambier CJ, Pinkerton KE, Koth LL. Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice. COPD. 2009 Apr; 6(2):86-94. PMID: 19378221; PMCID: PMC2873864.
    62. Mouadeb DA, Belafsky PC, Birchall M, Hood C, Konia T, Pinkerton KE. The effects of allergens and tobacco smoke on the laryngeal mucosa of guinea pigs. Otolaryngol Head Neck Surg. 2009 Apr; 140(4):493-7. PMID: 19328336.
      View in: PubMed
    63. Schenker MB, Pinkerton KE, Mitchell D, Vallyathan V, Elvine-Kreis B, Green FH. Pneumoconiosis from agricultural dust exposure among young California farmworkers. Environ Health Perspect. 2009 Jun; 117(6):988-94. PMID: 19590695; PMCID: PMC2702418.
    64. Wegesser TC, Pinkerton KE, Last JA. California wildfires of 2008: coarse and fine particulate matter toxicity. Environ Health Perspect. 2009 Jun; 117(6):893-7. PMID: 19590679; PMCID: PMC2702402.
    65. Avdalovic M, Putney L, Tyler N, Finkbeiner W, Pinkerton K, Hyde D. In utero and postnatal exposure to environmental tobacco smoke (ETS) alters alveolar and respiratory bronchiole (RB) growth and development in infant monkeys. Toxicol Pathol. 2009 Feb; 37(2):256-63. PMID: 19332666.
      View in: PubMed
    66. Madl AK, Pinkerton KE. Health effects of inhaled engineered and incidental nanoparticles. Crit Rev Toxicol. 2009; 39(8):629-58. PMID: 19743943.
      View in: PubMed
    67. Plummer LE, Pinkerton KE, Reynolds S, Meschke S, Mitloehner F, Bennett D, Smiley-Jewell S, Schenker MB. Aerosols in the agricultural setting. J Agromedicine. 2009; 14(4):413-6. PMID: 19894162.
      View in: PubMed
    68. Joad JP, Kott KS, Bric JM, Peake JL, Pinkerton KE. Effect of perinatal secondhand tobacco smoke exposure on in vivo and intrinsic airway structure/function in non-human primates. Toxicol Appl Pharmacol. 2009 Feb 01; 234(3):339-44. PMID: 19084550; PMCID: PMC2644053.
    69. Gospe SM, Joyce JA, Siebert JR, Jack RM, Pinkerton KE. Exposure to environmental tobacco smoke during pregnancy in rats yields less effect on indices of brain cell number and size than does postnatal exposure. Reprod Toxicol. 2009 Jan; 27(1):22-7. PMID: 19059474.
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    70. Pinkerton KE, Zhou Y, Zhong C, Smith KR, Teague SV, Kennedy IM, Ménache MG. Mechanisms of particulate matter toxicity in neonatal and young adult rat lungs. Res Rep Health Eff Inst. 2008 Oct; (135):3-41; discussion 43-52. PMID: 19203021.
      View in: PubMed
    71. Sekizawa S, Chen CY, Bechtold AG, Tabor JM, Bric JM, Pinkerton KE, Joad JP, Bonham AC. Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius second-order lung afferent neurons in young guinea pigs. Eur J Neurosci. 2008 Aug; 28(4):771-81. PMID: 18657181.
      View in: PubMed
    72. Yu M, Zheng X, Peake J, Joad JP, Pinkerton KE. Perinatal environmental tobacco smoke exposure alters the immune response and airway innervation in infant primates. J Allergy Clin Immunol. 2008 Sep; 122(3):640-7.e1. PMID: 18571708.
      View in: PubMed
    73. Chen CY, Chow D, Chiamvimonvat N, Glatter KA, Li N, He Y, Pinkerton KE, Bonham AC. Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H632-9. PMID: 18552155; PMCID: PMC2519230.
    74. Wang L, Joad JP, Zhong C, Pinkerton KE. Effects of environmental tobacco smoke exposure on pulmonary immune response in infant monkeys. J Allergy Clin Immunol. 2008 Aug; 122(2):400-6, 406.e1-5. PMID: 18502491.
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    75. Yu B, Kodavanti UP, Takeuchi M, Witschi H, Pinkerton KE. Acute tobacco smoke-induced airways inflammation in spontaneously hypertensive rats. Inhal Toxicol. 2008 May; 20(7):623-33. PMID: 18464051.
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    76. Schenker M, Pinkerton K. Research to practice in the agricultural workplace. J Agric Saf Health. 2008 Apr; 14(2):131-3. PMID: 18524280.
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    77. Wang L, Pinkerton KE. Detrimental effects of tobacco smoke exposure during development on postnatal lung function and asthma. Birth Defects Res C Embryo Today. 2008 Mar; 84(1):54-60. PMID: 18383132.
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    78. Zhong CY, Zhou YM, Pinkerton KE. NF-kappaB inhibition is involved in tobacco smoke-induced apoptosis in the lungs of rats. Toxicol Appl Pharmacol. 2008 Jul 15; 230(2):150-8. PMID: 18355884; PMCID: PMC2495769.
    79. Balbus JM, Maynard AD, Colvin VL, Castranova V, Daston GP, Denison RA, Dreher KL, Goering PL, Goldberg AM, Kulinowski KM, Monteiro-Riviere NA, Oberdörster G, Omenn GS, Pinkerton KE, Ramos KS, Rest KM, Sass JB, Silbergeld EK, Wong BA. Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop. Environ Health Perspect. 2007 Nov; 115(11):1654-9. PMID: 18007999; PMCID: PMC2072837.
    80. Hertz-Picciotto I, Baker RJ, Yap PS, Dostál M, Joad JP, Lipsett M, Greenfield T, Herr CE, Benes I, Shumway RH, Pinkerton KE, Srám R. Early childhood lower respiratory illness and air pollution. Environ Health Perspect. 2007 Oct; 115(10):1510-8. PMID: 17938744; PMCID: PMC2022654.
    81. Joad JP, Kott KS, Bric JM, Schelegle ES, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE. The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone. Toxicol Appl Pharmacol. 2008 Jan 15; 226(2):153-60. PMID: 17991502.
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    82. Wang L, Pinkerton KE. Air pollutant effects on fetal and early postnatal development. Birth Defects Res C Embryo Today. 2007 Sep; 81(3):144-54. PMID: 17963272.
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    83. Wang L, Joad JP, Abel K, Spinner A, Smiley-Jewell S, Liu H, Pinkerton KE. Effects of environmental tobacco smoke on the developing immune system of infant monkeys. J Allergy Clin Immunol. 2007 Aug; 120(2):445-51. PMID: 17482667.
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    84. Golub MS, Slotkin TA, Tarantal AF, Pinkerton KE. Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke. Brain Res. 2007 Jun 02; 1151:102-6. PMID: 17399690.
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    85. Coppens JT, Van Winkle LS, Pinkerton K, Plopper CG. Distribution of Clara cell secretory protein expression in the tracheobronchial airways of rhesus monkeys. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1155-62. PMID: 17237148.
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    86. Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM. Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology? Toxicol Pathol. 2007 Jan; 35(1):97-110. PMID: 17325978.
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    87. Jasinski J, Pinkerton KE, Kennedy IM, Leppert VJ. Spatially resolved energy electron loss spectroscopy studies of iron oxide nanoparticles. Microsc Microanal. 2006 Oct; 12(5):424-31. PMID: 16984669.
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    88. Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J. 2006 Oct; 20(12):2093-101. PMID: 17012261.
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    89. Smith KR, Veranth JM, Kodavanti UP, Aust AE, Pinkerton KE. Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. Toxicol Sci. 2006 Oct; 93(2):390-9. PMID: 16840564.
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    90. Tell LA, Smiley-Jewell S, Hinds D, Stephens KE, Teague SV, Plopper CG, Pinkerton KE. An aerosolized fluorescent microsphere technique for evaluating particle deposition in the avian respiratory tract. Avian Dis. 2006 Jun; 50(2):238-44. PMID: 16863074.
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    91. Zhong CY, Zhou YM, Joad JP, Pinkerton KE. Environmental tobacco smoke suppresses nuclear factor-kappaB signaling to increase apoptosis in infant monkey lungs. Am J Respir Crit Care Med. 2006 Aug 15; 174(4):428-36. PMID: 16709937; PMCID: PMC2648119.
    92. Pinkerton KE, Joad JP. Influence of air pollution on respiratory health during perinatal development. Clin Exp Pharmacol Physiol. 2006 Mar; 33(3):269-72. PMID: 16487273.
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    93. Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle ES, Gershwin LJ, Pinkerton KE. Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone. Toxicol Appl Pharmacol. 2006 Aug 01; 214(3):237-43. PMID: 16466656.
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    94. Slotkin TA, Pinkerton KE, Seidler FJ. Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. Environ Health Perspect. 2006 Jan; 114(1):34-9. PMID: 16393655; PMCID: PMC1332653.
    95. Wiedeman JA, Kaul R, Heuer LS, Thao NN, Pinkerton KE, Wenman WM. Tobacco smoke induces a persistent, but recoverable state in Chlamydia pneumoniae infection of human endothelial cells. Microb Pathog. 2005 Nov-Dec; 39(5-6):197-204. PMID: 16271847.
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    96. Kodavanti UP, Schladweiler MC, Ledbetter AD, McGee JK, Walsh L, Gilmour PS, Highfill JW, Davies D, Pinkerton KE, Richards JH, Crissman K, Andrews D, Costa DL. Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: roles of rat strains used and physicochemical properties. Environ Health Perspect. 2005 Nov; 113(11):1561-8. PMID: 16263512; PMCID: PMC1310919.
    97. Hertz-Picciotto I, Herr CE, Yap PS, Dostál M, Shumway RH, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Srám RJ. Air pollution and lymphocyte phenotype proportions in cord blood. Environ Health Perspect. 2005 Oct; 113(10):1391-8. PMID: 16203253; PMCID: PMC1281286.
    98. Zhong CY, Zhou YM, Douglas GC, Witschi H, Pinkerton KE. MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats. Carcinogenesis. 2005 Dec; 26(12):2187-95. PMID: 16051644.
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    99. Seymour BW, Peake JL, Pinkerton KE, Kurup VP, Gershwin LJ. Second-hand smoke increases nitric oxide and alters the IgE response in a murine model of allergic aspergillosis. Clin Dev Immunol. 2005 Jun; 12(2):113-24. PMID: 16050142; PMCID: PMC2270730.
    100. Arredondo J, Chernyavsky AI, Marubio LM, Beaudet AL, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: regulation of gene expression through alpha3beta2 nicotinic receptor in oral epithelial cells. Am J Pathol. 2005 Feb; 166(2):597-613. PMID: 15681842; PMCID: PMC1602318.
    101. Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma SJ, Hammock BD. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2186-91. PMID: 15684051; PMCID: PMC548576.
    102. Wiedeman JA, Kaul R, Heuer LS, Thao NN, Pinkerton KE, Wenman WM. Tobacco smoke induces persistent infection of Chlamydophila pneumoniae in HEp-2 cells. Microb Pathog. 2004 Sep; 37(3):141-8. PMID: 15351037.
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    103. Anderson KL, Pinkerton KE, Uyeminami D, Simons CT, Carstens MI, Carstens E. Antinociception induced by chronic exposure of rats to cigarette smoke. Neurosci Lett. 2004 Aug 05; 366(1):86-91. PMID: 15265596.
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    104. Witschi H, Espiritu I, Uyeminami D, Pinkerton KE, Raabe OG. Chemoprevention of tobacco smoke-induced lung cancer: what animal studies tell us. Chest. 2004 May; 125(5 Suppl):128S. PMID: 15136461.
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    105. Larson SD, Plopper CG, Baker G, Tarkington BK, Decile KC, Pinkerton K, Mansoor JK, Hyde DM, Schelegle ES. Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L286-95. PMID: 15064227.
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    106. Murin S, Pinkerton KE, Hubbard NE, Erickson K. The effect of cigarette smoke exposure on pulmonary metastatic disease in a murine model of metastatic breast cancer. Chest. 2004 Apr; 125(4):1467-71. PMID: 15078760.
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    107. Last JA, Ward R, Temple L, Pinkerton KE, Kenyon NJ. Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. Inhal Toxicol. 2004 Feb; 16(2):93-102. PMID: 15204782.
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    108. Witschi H, Espiritu I, Uyeminami D, Suffia M, Pinkerton KE. Lung tumor response in strain a mice exposed to tobacco smoke: some dose-effect relationships. Inhal Toxicol. 2004 Jan; 16(1):27-32. PMID: 14744662.
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    109. Pinkerton KE, Zhou YM, Teague SV, Peake JL, Walther RC, Kennedy IM, Leppert VJ, Aust AE. Reduced lung cell proliferation following short-term exposure to ultrafine soot and iron particles in neonatal rats: key to impaired lung growth? Inhal Toxicol. 2004; 16 Suppl 1:73-81. PMID: 15204795.
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    110. Joad JP, Munch PA, Bric JM, Evans SJ, Pinkerton KE, Chen CY, Bonham AC. Passive smoke effects on cough and airways in young guinea pigs: role of brainstem substance P. Am J Respir Crit Care Med. 2004 Feb 15; 169(4):499-504. PMID: 14644932.
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    111. Schelegle ES, Miller LA, Gershwin LJ, Fanucchi MV, Van Winkle LS, Gerriets JE, Walby WF, Mitchell V, Tarkington BK, Wong VJ, Baker GL, Pantle LM, Joad JP, Pinkerton KE, Wu R, Evans MJ, Hyde DM, Plopper CG. Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicol Appl Pharmacol. 2003 Aug 15; 191(1):74-85. PMID: 12915105.
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    112. Zhou YM, Zhong CY, Kennedy IM, Pinkerton KE. Pulmonary responses of acute exposure to ultrafine iron particles in healthy adult rats. Environ Toxicol. 2003 Aug; 18(4):227-35. PMID: 12900941.
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    113. Zhou YM, Zhong CY, Kennedy IM, Leppert VJ, Pinkerton KE. Oxidative stress and NFkappaB activation in the lungs of rats: a synergistic interaction between soot and iron particles. Toxicol Appl Pharmacol. 2003 Jul 15; 190(2):157-69. PMID: 12878045.
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    114. Smith KR, Kim S, Recendez JJ, Teague SV, Ménache MG, Grubbs DE, Sioutas C, Pinkerton KE. Airborne particles of the california central valley alter the lungs of healthy adult rats. Environ Health Perspect. 2003 Jun; 111(7):902-8; discussion A408-9. PMID: 12782490; PMCID: PMC1241523.
    115. Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol. 2003 Mar; 10(1):35-42. PMID: 14575156; PMCID: PMC2270675.
    116. Smith KR, Uyeminami DL, Kodavanti UP, Crapo JD, Chang LY, Pinkerton KE. Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant. Free Radic Biol Med. 2002 Oct 15; 33(8):1106-14. PMID: 12374622.
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    117. Yu M, Zheng X, Witschi H, Pinkerton KE. The role of interleukin-6 in pulmonary inflammation and injury induced by exposure to environmental air pollutants. Toxicol Sci. 2002 Aug; 68(2):488-97. PMID: 12151646.
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    118. Mullick AE, McDonald JM, Melkonian G, Talbot P, Pinkerton KE, Rutledge JC. Reactive carbonyls from tobacco smoke increase arterial endothelial layer injury. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H591-7. PMID: 12124206.
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    119. Kott KS, Pinkerton KE, Bric JM, Plopper CG, Avadhanam KP, Joad JP. Methacholine responsiveness of proximal and distal airways of monkeys and rats using videomicrometry. J Appl Physiol (1985). 2002 Mar; 92(3):989-96. PMID: 11842031.
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    120. Seymour BW, Friebertshauser KE, Peake JL, Pinkerton KE, Coffman RL, Gershwin LJ. Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. Dev Immunol. 2002 Mar; 9(1):47-54. PMID: 12353662; PMCID: PMC2276086.
    121. Nadadur SS, Pinkerton KE, Kodavanti UP. Pulmonary gene expression profiles of spontaneously hypertensive rats exposed to environmental tobacco smoke. Chest. 2002 Mar; 121(3 Suppl):83S-84S. PMID: 11893708.
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    122. Knight-Lozano CA, Young CG, Burow DL, Hu ZY, Uyeminami D, Pinkerton KE, Ischiropoulos H, Ballinger SW. Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation. 2002 Feb 19; 105(7):849-54. PMID: 11854126.
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    123. Witschi H, Espiritu I, Suffia M, Pinkerton KE. Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents. Carcinogenesis. 2002 Feb; 23(2):289-94. PMID: 11872634.
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    124. Yu M, Pinkerton KE, Witschi H. Short-term exposure to aged and diluted sidestream cigarette smoke enhances ozone-induced lung injury in B6C3F1 mice. Toxicol Sci. 2002 Jan; 65(1):99-106. PMID: 11752689.
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