Crystal M Ripplinger

Title(s)Professor, Pharmacology
SchoolSchool of Medicine
Address2219 Tupper Hall
CA 95616
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    Collapse Research 
    Collapse Research Activities and Funding
    Sympathetic remodeling and ventricular arrhythmia
    NIH R01HL111600Apr 16, 2012 - Jun 30, 2025
    Role: Principal Investigator
    Neurotrophins and post-infarct plasticity in cardiac sympathetic neurons
    NIH R01HL093056Jul 15, 2009 - Jun 30, 2023
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Looking Backward to Plan for Forward. Am J Physiol Heart Circ Physiol. 2024 Mar 29. Lindsey ML, Kirk JA, LeBlanc AJ, Brunt KR, Carter JR, Hansell Keehan K, Ripplinger CM, Kleinbongard P, Kassiri Z. PMID: 38551484.
      View in: PubMed   Mentions:    Fields:    
    2. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart. Am J Physiol Heart Circ Physiol. 2024 Mar 29. Guevara A, Smith CER, Caldwell JL, Ngo L, Mott LR, Lee IJ, Tapa S, Wang Z, Wang L, Woodward WR, Ng GA, Habecker BA, Ripplinger CM. PMID: 38551482.
      View in: PubMed   Mentions:    Fields:    
    3. The heart of physiological reports. Physiol Rep. 2024 Mar; 12(5):e15962. Lindsey ML, Brunt KR, Kleinbongard P, Carter JR, Ripplinger CM, Kassiri Z, Hansell Keehan K, LeBlanc AJ, Kirk JA. PMID: 38439748; PMCID: PMC10912920.
      View in: PubMed   Mentions:    Fields:    
    4. The heart-bone connection: relationships between myocardial infarction and osteoporotic fracture. Am J Physiol Heart Circ Physiol. 2024 Mar 01; 326(3):H845-H856. Tjandra PM, Ripplinger CM, Christiansen BA. PMID: 38305753.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Sex as a biological variable for cardiovascular physiology. Am J Physiol Heart Circ Physiol. 2024 Mar 01; 326(3):H459-H469. Lindsey ML, Usselman CW, Ripplinger CM, Carter JR, DeLeon-Pennell KY. PMID: 38099847.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart. bioRxiv. 2023 Nov 23. Guevara A, Smith CER, Caldwell JL, Ngo L, Mott LR, Lee IJ, Tapa I, Wang Z, Wang L, Woodward WR, Ng GA, Habecker BA, Ripplinger CM. PMID: 38045290; PMCID: PMC10690259.
      View in: PubMed   Mentions:
    7. Paralysis by analysis: Overcoming cardiac contraction with computer vision. Proc Natl Acad Sci U S A. 2023 10 17; 120(42):e2314448120. Christoph J, Ripplinger CM. PMID: 37792520; PMCID: PMC10589680.
      View in: PubMed   Mentions:    Fields:    
    8. A multiscale predictive digital twin for neurocardiac modulation. J Physiol. 2023 09; 601(17):3789-3812. Yang PC, Rose A, DeMarco KR, Dawson JRD, Han Y, Jeng MT, Harvey RD, Santana LF, Ripplinger CM, Vorobyov I, Lewis TJ, Clancy CE. PMID: 37528537; PMCID: PMC10528740.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Autonomic control of ventricular function in health and disease: current state of the art. Clin Auton Res. 2023 08; 33(4):491-517. van Weperen VYH, Ripplinger CM, Vaseghi M. PMID: 37166736; PMCID: PMC10173946.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Spring cleaning: freshening up the portfolio. Am J Physiol Heart Circ Physiol. 2023 06 01; 324(6):H840-H842. Lindsey ML, Kassiri Z, LeBlanc AJ, Ripplinger CM, Kirk JA, Carter JR, Kleinbongard P, Brunt KR. PMID: 37115630; PMCID: PMC10190828.
      View in: PubMed   Mentions:    Fields:    
    11. We asked and you answered. Am J Physiol Heart Circ Physiol. 2023 05 01; 324(5):H657-H658. Lindsey ML, Kleinbongard P, Kassiri Z, Carter JR, Hansell Keehan K, Ripplinger CM, LeBlanc AJ, Brunt KR, Kirk JA. PMID: 36930658; PMCID: PMC10085547.
      View in: PubMed   Mentions: 1     Fields:    
    12. Diversity of cells and signals in the cardiovascular system. J Physiol. 2023 07; 601(13):2547-2592. Grandi E, Navedo MF, Saucerman JJ, Bers DM, Chiamvimonvat N, Dixon RE, Dobrev D, Gomez AM, Harraz OF, Hegyi B, Jones DK, Krogh-Madsen T, Murfee WL, Nystoriak MA, Posnack NG, Ripplinger CM, Veeraraghavan R, Weinberg S. PMID: 36744541; PMCID: PMC10313794.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics. Sci Adv. 2023 01 20; 9(3):eadd5799. Caldwell JL, Lee IJ, Ngo L, Wang L, Bahriz S, Xu B, Bers DM, Navedo MF, Bossuyt J, Xiang YK, Ripplinger CM. PMID: 36662864; PMCID: PMC9858506.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Sex still matters in cardiovascular research. Am J Physiol Heart Circ Physiol. 2023 01 01; 324(1):H79-H81. Lindsey ML, Carter JR, Ripplinger CM, Kassiri Z, Hansell Keehan K, Brunt KR, Kirk JA, Kleinbongard P, LeBlanc AJ. PMID: 36487186; PMCID: PMC9799132.
      View in: PubMed   Mentions: 4     Fields:    
    15. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals. Am J Physiol Heart Circ Physiol. 2022 12 01; 323(6):H1137-H1166. Ripplinger CM, Glukhov AV, Kay MW, Boukens BJ, Chiamvimonvat N, Delisle BP, Fabritz L, Hund TJ, Knollmann BC, Li N, Murray KT, Poelzing S, Quinn TA, Remme CA, Rentschler SL, Rose RA, Posnack NG. PMID: 36269644; PMCID: PMC9678409.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    16. Automated Object Detection in Experimental Data Using Combination of Unsupervised and Supervised Methods. Front Physiol. 2022; 13:805161. Wu Y, Wang Z, Ripplinger CM, Sato D. PMID: 35464087; PMCID: PMC9019745.
      View in: PubMed   Mentions: 1  
    17. Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop. JACC Basic Transl Sci. 2022 Mar; 7(3):265-293. Mehra R, Tjurmina OA, Ajijola OA, Arora R, Bolser DC, Chapleau MW, Chen PS, Clancy CE, Delisle BP, Gold MR, Goldberger JJ, Goldstein DS, Habecker BA, Handoko ML, Harvey R, Hummel JP, Hund T, Meyer C, Redline S, Ripplinger CM, Simon MA, Somers VK, Stavrakis S, Taylor-Clark T, Undem BJ, Verrier RL, Zucker IH, Sopko G, Shivkumar K. PMID: 35411324; PMCID: PMC8993767.
      View in: PubMed   Mentions: 10  
    18. Deciphering cellular signals in adult mouse sinoatrial node cells. iScience. 2022 Jan 21; 25(1):103693. Reddy GR, Ren L, Thai PN, Caldwell JL, Zaccolo M, Bossuyt J, Ripplinger CM, Xiang YK, Nieves-Cintrón M, Chiamvimonvat N, Navedo MF. PMID: 35036877; PMCID: PMC8749457.
      View in: PubMed   Mentions: 4  
    19. Quantitative cross-species translators of cardiac myocyte electrophysiology: Model training, experimental validation, and applications. Sci Adv. 2021 Nov 19; 7(47):eabg0927. Morotti S, Liu C, Hegyi B, Ni H, Fogli Iseppe A, Wang L, Pritoni M, Ripplinger CM, Bers DM, Edwards AG, Grandi E. PMID: 34788089; PMCID: PMC8598003.
      View in: PubMed   Mentions: 14     Fields:    
    20. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations. Circ Arrhythm Electrophysiol. 2021 11; 14(11):e010190. Delisle BP, George AL, Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer FAJL, Shivkumar K, Shea SA, Balijepalli RC. PMID: 34719257; PMCID: PMC8865094.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    21. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects. Circ Arrhythm Electrophysiol. 2021 11; 14(11):e010181. Delisle BP, George AL, Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer FAJL, Shivkumar K, Shea SA, Balijepalli RC. PMID: 34719240; PMCID: PMC8815462.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    22. Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research. Am J Physiol Heart Circ Physiol. 2021 12 01; 321(6):H1005-H1013. Swift LM, Kay MW, Ripplinger CM, Posnack NG. PMID: 34623183; PMCID: PMC8782655.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    23. Guidelines for in vivo mouse models of myocardial infarction. Am J Physiol Heart Circ Physiol. 2021 12 01; 321(6):H1056-H1073. Lindsey ML, Brunt KR, Kirk JA, Kleinbongard P, Calvert JW, de Castro Brás LE, DeLeon-Pennell KY, Del Re DP, Frangogiannis NG, Frantz S, Gumina RJ, Halade GV, Jones SP, Ritchie RH, Spinale FG, Thorp EB, Ripplinger CM, Kassiri Z. PMID: 34623181; PMCID: PMC8834230.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    24. Reinforcing rigor and reproducibility expectations for use of sex and gender in cardiovascular research. Am J Physiol Heart Circ Physiol. 2021 11 01; 321(5):H819-H824. Lindsey ML, LeBlanc AJ, Ripplinger CM, Carter JR, Kirk JA, Hansell Keehan K, Brunt KR, Kleinbongard P, Kassiri Z. PMID: 34524922.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    25. Reperfused vs. nonreperfused myocardial infarction: when to use which model. Am J Physiol Heart Circ Physiol. 2021 07 01; 321(1):H208-H213. Lindsey ML, de Castro Brás LE, DeLeon-Pennell KY, Frangogiannis NG, Halade GV, O'Meara CC, Spinale FG, Kassiri Z, Kirk JA, Kleinbongard P, Ripplinger CM, Brunt KR. PMID: 34114891; PMCID: PMC8321810.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    26. Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart. Front Physiol. 2021; 12:656516. Wang L, Myles RC, Lee IJ, Bers DM, Ripplinger CM. PMID: 34045974; PMCID: PMC8144333.
      View in: PubMed   Mentions: 11  
    27. CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia. Circ Res. 2021 06 25; 129(1):98-113. Hegyi B, Fasoli A, Ko CY, Van BW, Alim CC, Shen EY, Ciccozzi MM, Tapa S, Ripplinger CM, Erickson JR, Bossuyt J, Bers DM. PMID: 33926209; PMCID: PMC8221539.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    28. We are the change we seek. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1411-H1414. Lindsey ML, Kassiri Z, Hansell Keehan K, Brunt KR, Carter JR, Kirk JA, Kleinbongard P, LeBlanc AJ, Ripplinger CM. PMID: 33710925; PMCID: PMC8260391.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss. Sci Rep. 2020 11 02; 10(1):18801. Tapa S, Wang L, Francis Stuart SD, Wang Z, Jiang Y, Habecker BA, Ripplinger CM. PMID: 33139790; PMCID: PMC7608682.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    30. Systemic bone loss following myocardial infarction in mice. J Orthop Res. 2021 04; 39(4):739-749. Tjandra PM, Paralkar MP, Osipov B, Chen YJ, Zhao F, Ripplinger CM, Christiansen BA. PMID: 32965732; PMCID: PMC8218775.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    31. Aging Disrupts Normal Time-of-Day Variation in Cardiac Electrophysiology. Circ Arrhythm Electrophysiol. 2020 09; 13(9):e008093. Wang Z, Tapa S, Francis Stuart SD, Wang L, Bossuyt J, Delisle BP, Ripplinger CM. PMID: 32706628; PMCID: PMC7494582.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    32. Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction. Am J Physiol Heart Circ Physiol. 2020 03 01; 318(3):H558-H565. Wang L, Olivas A, Francis Stuart SD, Tapa S, Blake MR, Woodward WR, Habecker BA, Ripplinger CM. PMID: 31975627; PMCID: PMC7199228.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Putting the pieces together using in vivo optical mapping. Cardiovasc Res. 2019 09 01; 115(11):1574-1575. Wang L, Ripplinger CM. PMID: 30924872; PMCID: PMC6704385.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    34. Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts. J Physiol. 2019 08; 597(15):3867-3883. Wang L, Morotti S, Tapa S, Francis Stuart SD, Jiang Y, Wang Z, Myles RC, Brack KE, Ng GA, Bers DM, Grandi E, Ripplinger CM. PMID: 31215643; PMCID: PMC6675632.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    35. Antiarrhythmic mechanisms of beta blocker therapy. Pharmacol Res. 2019 08; 146:104274. Grandi E, Ripplinger CM. PMID: 31100336; PMCID: PMC6679787.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    36. Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality. Cardiovasc Res. 2019 02 01; 115(2):395-408. Lindsey ML, Jung M, Yabluchanskiy A, Cannon PL, Iyer RP, Flynn ER, DeLeon-Pennell KY, Valerio FM, Harrison CL, Ripplinger CM, Hall ME, Ma Y. PMID: 30169632; PMCID: PMC6341225.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    37. Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model. Environ Health Perspect. 2018 12; 126(12):127001. Wang Z, Wang L, Tapa S, Pinkerton KE, Chen CY, Ripplinger CM. PMID: 30675795; PMCID: PMC6371715.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsPHPublic Health
    38. Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation. J Physiol. 2018 09; 596(17):3977-3991. Francis Stuart SD, Wang L, Woodard WR, Ng GA, Habecker BA, Ripplinger CM. PMID: 29938794; PMCID: PMC6117583.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    39. The best thing since sliced bread? Optical mapping of transverse cardiac slices in the mouse heart. J Physiol. 2018 09; 596(17):3825-3826. Ripplinger CM. PMID: 29974471; PMCID: PMC6117585.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    40. Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol. 2018 04 01; 314(4):H812-H838. Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, Recchia FA, Schwartz Longacre L, Ripplinger CM, Van Eyk JE, Heusch G. PMID: 29351451; PMCID: PMC5966768.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    41. Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility. Am J Physiol Heart Circ Physiol. 2018 03 01; 314(3):H415-H423. Parrish DC, Francis Stuart SD, Olivas A, Wang L, Nykjaer A, Ripplinger CM, Habecker BA. PMID: 29101167; PMCID: PMC5899257.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    42. Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart. Circ Res. 2017 Dec 08; 121(12):1379-1391. Lang D, Sato D, Jiang Y, Ginsburg KS, Ripplinger CM, Bers DM. PMID: 28970285; PMCID: PMC5722688.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    43. From drugs to devices and back again: chemical vagal nerve stimulation for the treatment of heart failure. Cardiovasc Res. 2017 09 01; 113(11):1270-1272. Ripplinger CM. PMID: 28859301; PMCID: PMC5852535.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    44. β-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia. Front Physiol. 2017; 8:630. Murphy SR, Wang L, Wang Z, Domondon P, Lang D, Habecker BA, Myles RC, Ripplinger CM. PMID: 28894423; PMCID: PMC5581400.
      View in: PubMed   Mentions: 4  
    45. Why publish in the American Journal of Physiology-Heart and Circulatory Physiology? Am J Physiol Heart Circ Physiol. 2017 08 01; 313(2):H221-H223. Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger CM, Wolin MS. PMID: 28626081.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    46. Antiarrhythmic effects of interleukin 1 inhibition after myocardial infarction. Heart Rhythm. 2017 05; 14(5):727-736. De Jesus NM, Wang L, Lai J, Rigor RR, Francis Stuart SD, Bers DM, Lindsey ML, Ripplinger CM. PMID: 28111350; PMCID: PMC5403568.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    47. Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics. J Physiol. 2017 04 01; 595(7):2229-2252. Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger CM, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, Bers DM, Nerbonne JM. PMID: 27808412; PMCID: PMC5374105.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    48. Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease. J Physiol. 2016 07 15; 594(14):3853-75. Habecker BA, Anderson ME, Birren SJ, Fukuda K, Herring N, Hoover DB, Kanazawa H, Paterson DJ, Ripplinger CM. PMID: 27060296; PMCID: PMC4945713.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    49. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. PMID: 27162031; PMCID: PMC4869994.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    50. Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias. Circ Arrhythm Electrophysiol. 2016 Feb; 9(2):e001359. Gardner RT, Ripplinger CM, Myles RC, Habecker BA. PMID: 26810594; PMCID: PMC4730917.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    51. Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130. J Neurosci. 2016 Jan 13; 36(2):479-88. Olivas A, Gardner RT, Wang L, Ripplinger CM, Woodward WR, Habecker BA. PMID: 26758839; PMCID: PMC4710771.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    52. The nervous heart. Prog Biophys Mol Biol. 2016 Jan; 120(1-3):199-209. Ripplinger CM, Noujaim SF, Linz D. PMID: 26780507; PMCID: PMC4808395.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    53. Recent developments in biophysics & molecular biology of heart rhythm. Prog Biophys Mol Biol. 2016 Jan; 120(1-3):1-2. Quinn TA, Ripplinger CM. PMID: 26777585.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction. J Mol Cell Cardiol. 2016 Feb; 91:114-22. Francis Stuart SD, De Jesus NM, Lindsey ML, Ripplinger CM. PMID: 26739214; PMCID: PMC4764395.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    55. Optical Mapping of Intra-Sarcoplasmic Reticulum Ca2+ and Transmembrane Potential in the Langendorff-perfused Rabbit Heart. J Vis Exp. 2015 Sep 10; (103). Wang L, De Jesus NM, Ripplinger CM. PMID: 26382577; PMCID: PMC4676338.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    56. Ion Channels in the Heart. Compr Physiol. 2015 Jul 01; 5(3):1423-64. Bartos DC, Grandi E, Ripplinger CM. PMID: 26140724; PMCID: PMC4516287.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    57. Dual Vm/Ca imaging of premature ventricular contractions: bridging the gap of anatomical scales. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):529-30. Ripplinger CM, Efimov IR. PMID: 26082526; PMCID: PMC4617379.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    58. Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation. J Mol Cell Cardiol. 2015 Jul; 84:1-9. Hammer KP, Ljubojevic S, Ripplinger CM, Pieske BM, Bers DM. PMID: 25828762; PMCID: PMC4500534.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    59. A leap(frog) forward in understanding focal arrhythmia. J Physiol. 2015 Mar 15; 593(6):1383-4. Ripplinger CM. PMID: 25772292; PMCID: PMC4376417.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    60. Targeting protein tyrosine phosphatase σ after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias. Nat Commun. 2015 Feb 02; 6:6235. Gardner RT, Wang L, Lang BT, Cregg JM, Dunbar CL, Woodward WR, Silver J, Ripplinger CM, Habecker BA. PMID: 25639594; PMCID: PMC4315356.
      View in: PubMed   Mentions: 60     Fields:    Translation:Animals
    61. Mouse models of cardiac conduction system markers: revealing the past, present, and future of pacemaking and conduction. Trends Cardiovasc Med. 2015 Jan; 25(1):10-1. Ripplinger CM. PMID: 25446050.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    62. Atherosclerosis exacerbates arrhythmia following myocardial infarction: Role of myocardial inflammation. Heart Rhythm. 2015 Jan; 12(1):169-78. De Jesus NM, Wang L, Herren AW, Wang J, Shenasa F, Bers DM, Lindsey ML, Ripplinger CM. PMID: 25304682; PMCID: PMC4277908.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    63. Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart. J Physiol. 2015 Mar 15; 593(6):1479-93. Myles RC, Wang L, Bers DM, Ripplinger CM. PMID: 25772297; PMCID: PMC4376425.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    64. In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2014 Oct; 22(10):1461-9. Satkunananthan PB, Anderson MJ, De Jesus NM, Haudenschild DR, Ripplinger CM, Christiansen BA. PMID: 25278057; PMCID: PMC4185155.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    65. P. gingivalis lipopolysaccharide intensifies inflammation post-myocardial infarction through matrix metalloproteinase-9. J Mol Cell Cardiol. 2014 Nov; 76:218-26. DeLeon-Pennell KY, de Castro Brás LE, Iyer RP, Bratton DR, Jin YF, Ripplinger CM, Lindsey ML. PMID: 25240641; PMCID: PMC4250428.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    66. Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation. Circ Res. 2014 Apr 25; 114(9):1410-21. Wang L, Myles RC, De Jesus NM, Ohlendorf AK, Bers DM, Ripplinger CM. PMID: 24568740; PMCID: PMC4000583.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    67. Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes. Stem Cell Reports. 2013; 1(5):387-96. Feinberg AW, Ripplinger CM, van der Meer P, Sheehy SP, Domian I, Chien KR, Parker KK. PMID: 24286027; PMCID: PMC3841251.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    68. Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature. 2013 Oct 17; 502(7471):372-6. Erickson JR, Pereira L, Wang L, Han G, Ferguson A, Dao K, Copeland RJ, Despa F, Hart GW, Ripplinger CM, Bers DM. PMID: 24077098; PMCID: PMC3801227.
      View in: PubMed   Mentions: 289     Fields:    Translation:HumansAnimalsCells
    69. Panoramic Optical Imaging of Cardiac Arrhythmias. . 2013 Jan 10; 90-97. Ripplinger RC. .
      View in: Publisher Site   Mentions:
    70. Imaging Fiber Orientation with Optical Coherence Tomography and Diffusion-Tensor Magnetic Resonance Imaging and its Role in Arrhythmogenesis. . 2013 Jan 10; 589-597. Myles MR, Ripplinger RC. .
      View in: Publisher Site   Mentions:
    71. Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2616-24. Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA. PMID: 22995524; PMCID: PMC3516622.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    72. A tissue-engineered jellyfish with biomimetic propulsion. Nat Biotechnol. 2012 Aug; 30(8):792-7. Nawroth JC, Lee H, Feinberg AW, Ripplinger CM, McCain ML, Grosberg A, Dabiri JO, Parker KK. PMID: 22820316; PMCID: PMC4026938.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    73. Contractile and electrophysiologic characterization of optimized self-organizing engineered heart tissue. Ann Thorac Surg. 2012 Oct; 94(4):1241-8; discussion 1249. Sondergaard CS, Mathews G, Wang L, Jeffreys A, Sahota A, Wood M, Ripplinger CM, Si MS. PMID: 22795054; PMCID: PMC4075435.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    74. Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture. Biomaterials. 2012 Aug; 33(23):5732-41. Feinberg AW, Alford PW, Jin H, Ripplinger CM, Werdich AA, Sheehy SP, Grosberg A, Parker KK. PMID: 22594976; PMCID: PMC4026933.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    75. Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia. Circ Res. 2012 May 25; 110(11):1454-64. Myles RC, Wang L, Kang C, Bers DM, Ripplinger CM. PMID: 22539768; PMCID: PMC3396564.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    76. Human biological pacemakers: intrinsic variability and stability. Circulation. 2012 Feb 21; 125(7):856-8. Ripplinger CM, Bers DM. PMID: 22261197.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Sci Transl Med. 2011 Aug 31; 3(98):98ra83. Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger CM, Kass RS, Clancy CE. PMID: 21885405; PMCID: PMC3328405.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimals
    78. Termination of sustained atrial flutter and fibrillation using low-voltage multiple-shock therapy. Heart Rhythm. 2011 Jan; 8(1):101-8. Ambrosi CM, Ripplinger CM, Efimov IR, Fedorov VV. PMID: 20969974; PMCID: PMC3384750.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    79. Multiple monophasic shocks improve electrotherapy of ventricular tachycardia in a rabbit model of chronic infarction. Heart Rhythm. 2009 Jul; 6(7):1020-7. Li W, Ripplinger CM, Lou Q, Efimov IR. PMID: 19560090; PMCID: PMC2813769.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    80. Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation. 2009 Mar 17; 119(10):1398-407. Lombardi R, Rodriguez G, Chen SN, Ripplinger CM, Li W, Chen J, Willerson JT, Betocchi S, Wickline SA, Efimov IR, Marian AJ. PMID: 19255346; PMCID: PMC2773801.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    81. The Virtual Electrode Hypothesis of Defibrillation. . 2009 Jan 1; 331-356. Ripplinger RC, Efimov EI. .
      View in: Publisher Site   Mentions:
    82. Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion. Heart Rhythm. 2009 Jan; 6(1):87-97. Ripplinger CM, Lou Q, Li W, Hadley J, Efimov IR. PMID: 18996057; PMCID: PMC2650268.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    83. Bimodal biophotonic imaging of the structure-function relationship in cardiac tissue. J Biomed Opt. 2008 Sep-Oct; 13(5):054012. Hucker WJ, Ripplinger CM, Fleming CP, Fedorov VV, Rollins AM, Efimov IR. PMID: 19021392; PMCID: PMC2719892.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    84. Quantitative panoramic imaging of epicardial electrical activity. Ann Biomed Eng. 2008 Oct; 36(10):1649-58. Lou Q, Ripplinger CM, Bayly PV, Efimov IR. PMID: 18654852; PMCID: PMC2714651.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    85. Quantification of cardiac fiber orientation using optical coherence tomography. J Biomed Opt. 2008 May-Jun; 13(3):030505. Fleming CP, Ripplinger CM, Webb B, Efimov IR, Rollins AM. PMID: 18601522; PMCID: PMC2714642.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    86. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ Res. 2007 Nov 09; 101(10):1049-57. Ripplinger CM, Li W, Hadley J, Chen J, Rothenberg F, Lombardi R, Wickline SA, Marian AJ, Efimov IR. PMID: 17885214; PMCID: PMC2366809.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    87. Three-dimensional panoramic imaging of cardiac arrhythmias in rabbit heart. J Biomed Opt. 2007 Jul-Aug; 12(4):044019. Qu F, Ripplinger CM, Nikolski VP, Grimm C, Efimov IR. PMID: 17867823.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    88. Effects of pacing rate on mechanical restitution within the in vivo canine heart: study of the force-frequency relationship. J Cardiovasc Electrophysiol. 2007 Feb; 18(2):212-7. Ahlberg SE, Ripplinger CM, Skadsberg ND, Iaizzo PA, Mulligan LJ. PMID: 17239141.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    89. Virtual electrode hypothesis of defibrillation. Heart Rhythm. 2006 Sep; 3(9):1100-2. Efimov I, Ripplinger CM. PMID: 16945810.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    90. Mechanisms of unpinning and termination of ventricular tachycardia. Am J Physiol Heart Circ Physiol. 2006 Jul; 291(1):H184-92. Ripplinger CM, Krinsky VI, Nikolski VP, Efimov IR. PMID: 16501014.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    91. Tornado in a dish: revealing the mechanisms of ventricular arrhythmias in engineered cardiac tissues. Cardiovasc Res. 2006 Feb 01; 69(2):307-8. Efimov IR, Ripplinger CM. PMID: 16325163.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    92. Importance of geometry and refractory period in sustaining atrial fibrillation: testing the critical mass hypothesis. Circulation. 2005 Aug 30; 112(9 Suppl):I7-13. Byrd GD, Prasad SM, Ripplinger CM, Cassilly TR, Schuessler RB, Boineau JP, Damiano RJ. PMID: 16159868.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    93. Toward a new method of analyzing cardiac performance. Biomed Sci Instrum. 2001; 37:313-8. Ripplinger CM, Ewert DL, Koenig SC. PMID: 11347409.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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