Blaine A Christiansen

Title(s)Professor in Residence, MED: Orthopaedic Surgery
SchoolSchool of Medicine
Address2700 Stockton Blvd Ste 2301
CA 95817
Phone916-734-3974
ORCID ORCID Icon0000-0002-0105-6458 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Nebraska, Lincoln, NEBS12/2001Biological Systems Engineering
    Washington University, St. Louis, MOMS05/2004Biomedical Engineering
    Washington University, St. Louis, MOPh.D.12/2007Biomedical Engineering
    Beth Israel Deaconess Medical Center, Boston, MAPostdoctoral Fellowship02/2010Orthopaedic Research
    Collapse Awards and Honors
    American Society of Mechanical Engineers 2005Summer Bioengineering Conference, 1st Place - Student Paper Competition
    United States Bone and Joint Decade 2010  - 2011Young Investigators Initiative
    American Society for Bone and Mineral Research 2010Young Investigator Award
    International Bone and Mineral Society/American Society for Bone and Mineral Research2011Harold M. Frost Young Investigator Award
    American Society for Bone and Mineral Research2014Junior Faculty Osteoporosis Research Award
    International Bone and Mineral Society2014Alice L. Jee Memorial Young Investigator Award
    American Society for Bone and Mineral Research2021Mid-Career Travel Grant

    Collapse Overview 
    Collapse Overview
    Dr. Christiansen a biomedical engineer with expertise in musculoskeletal adaptation, mechanobiology, bone imaging, and small animal models of injury, mechanical loading, or unloading (disuse). His primary research interest is the adaptation of musculoskeletal tissues to the mechanical environment, injury, and aging, and how these adaptations can lead to clinically relevant diseases such as osteoporosis and osteoarthritis.
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Systemic Bone Loss Following Fracture in Humans
    NIH R01AG078347Sep 30, 2023 - May 31, 2028
    Role: Co-PI
    Modification of Post-Traumatic Osteoarthritis Progression with Joint Unloading
    NIH R01AR075013Mar 1, 2020 - Dec 31, 2024
    Role: Principal Investigator
    Mechanisms of Systemic Bone Loss Following Femur Fracture in Mice
    NIH/NIAMS R01AR071459Sep 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    The role of the inflammatory response in bone and cartilage changes following non
    NIH/NIAMS K01AR062603Sep 10, 2012 - Aug 31, 2017
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Osteocytic oxygen sensing: Distinct impacts of VHL and HIF-2alpha on bone integrity. Bone. 2024 Nov 26; 192:117339. Mendoza SV, Wells KV, Murugesh DK, Hum NR, Sebastian A, Gorman BM, Wong A, Osipov B, Christiansen BA, Loots GG, Robling AG, Yellowley CE, Genetos DC. PMID: 39603372.
      View in: PubMed   Mentions:
    2. Polytrauma impairs fracture healing accompanied by increased persistence of innate inflammatory stimuli and reduced adaptive response. J Orthop Res. 2024 Nov 17. Saiz AM, Rahmati M, Gresham RCH, Baldini TD, Burgan J, Lee MA, Osipov B, Christiansen BA, Khassawna TE, Wieland DCF, Marinho AL, Blanchet C, Czachor M, Working ZM, Bahney CS, Leach JK. PMID: 39550711.
      View in: PubMed   Mentions:    Fields:    
    3. Altered post-fracture systemic bone loss in a mouse model of osteocyte dysfunction. JBMR Plus. 2024 Dec; 8(12):ziae135. Osipov B, Emami AJ, Cunningham HC, Orr S, Lin YY, Jbeily EH, Punati RS, Murugesh DK, Zukowski HM, Loots GG, Carney R, Vargas D, Ferguson VL, Christiansen BA. PMID: 39605879; PMCID: PMC11601886.
      View in: PubMed   Mentions:
    4. Concurrent Joint Contact in Anterior Cruciate Ligament Injury induces cartilage micro-injury and subchondral bone sclerosis, resulting in knee osteoarthritis. bioRxiv. 2024 Jul 01. Takahata K, Lin YY, Osipov B, Arakawa K, Enomoto S, Christiansen BA, Kokubun T. PMID: 38766109; PMCID: PMC11100711.
      View in: PubMed   Mentions:
    5. Saturated fatty acids negatively affect musculoskeletal tissues in vitro and in vivo. Matrix Biol Plus. 2024 Aug; 23:100153. Lin RT, Osipov B, Steffen D, Chamberlin M, Pathak SJ, Christiansen BA, Paulussen KJM, Baar K. PMID: 38882396; PMCID: PMC11179588.
      View in: PubMed   Mentions:
    6. Surgical restabilization reduces the progression of post-traumatic osteoarthritis initiated by ACL rupture in mice. Osteoarthritis Cartilage. 2024 Aug; 32(8):909-920. Lin YY, Jbeily EH, Tjandra PM, Pride MC, Lopez-Torres M, Elmankabadi SB, Delman CM, Biris KK, Bang H, Silverman JL, Lee CA, Christiansen BA. PMID: 38697509.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. The heart-bone connection: relationships between myocardial infarction and osteoporotic fracture. Am J Physiol Heart Circ Physiol. 2024 03 01; 326(3):H845-H856. Tjandra PM, Ripplinger CM, Christiansen BA. PMID: 38305753; PMCID: PMC11062618.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. A 0.05 m Change in Inertial Measurement Unit Placement Alters Time and Frequency Domain Metrics during Running. Sensors (Basel). 2024 Jan 19; 24(2). Kiernan D, Katzman ZD, Hawkins DA, Christiansen BA. PMID: 38276348; PMCID: PMC10820910.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Mef2c regulates bone mass through Sost-dependent and -independent mechanisms. Bone. 2024 02; 179:116976. Morfin C, Sebastian A, Wilson SP, Amiri B, Murugesh DK, Hum NR, Christiansen BA, Loots GG. PMID: 38042445.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    10. Validation of a Low-Cost Portable Device for Inducing Noninvasive Anterior Cruciate Ligament Injury in Mice. J Biomech Eng. 2023 11 01; 145(11). Jbeily EH, Lin YY, Elmankabadi SB, Osipov B, June RK, Christiansen BA. PMID: 37417814; PMCID: PMC10777735.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    11. Non-Invasive Compression-Induced Anterior Cruciate Ligament (ACL) Injury and In Vivo Imaging of Protease Activity in Mice. J Vis Exp. 2023 09 29; (199). Lin YY, Christiansen BA. PMID: 37843296; PMCID: PMC10680551.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Antibiotic Treatment Prior to Injury Abrogates the Detrimental Effects of LPS in STR/ort Mice Susceptible to Osteoarthritis Development. JBMR Plus. 2023 Aug; 7(8):e10759. Mendez ME, Murugesh DK, Christiansen BA, Loots GG. PMID: 37614305; PMCID: PMC10443070.
      View in: PubMed   Mentions: 1  
    13. Using uniaxial tensile testing to evaluate the biomechanical properties of bladder tissue after spinal cord injury in rat model. J Biomech. 2023 05; 152:111571. Hu JC, Osborn SL, Sanchez PC, Xu W, Christiansen BA, Kurzrock EA. PMID: 37027962.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. Acute bone loss following SARS-CoV-2 infection in mice. J Orthop Res. 2023 09; 41(9):1945-1952. Haudenschild AK, Christiansen BA, Orr S, Ball EE, Weiss CM, Liu H, Fyhrie DP, Yik JHN, Coffey LL, Haudenschild DR. PMID: 36815216; PMCID: PMC10440245.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    15. Degradation-Resistant Hypoxia Inducible Factor-2α in Murine Osteocytes Promotes a High Bone Mass Phenotype. JBMR Plus. 2023 Apr; 7(4):e10724. Mendoza SV, Murugesh DK, Christiansen BA, Genetos ZO, Loots GG, Genetos DC, Yellowley CE. PMID: 37065633; PMCID: PMC10097640.
      View in: PubMed   Mentions: 1  
    16. Small-Animal Compression Models of Osteoarthritis. Methods Mol Biol. 2023; 2598:345-356. Christiansen BA, Chan DD, van der Meulen MCH, Maerz T. PMID: 36355304; PMCID: PMC10521326.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Differential bone adaptation to mechanical unloading and reloading in young, old, and osteocyte deficient mice. Bone. 2023 02; 167:116646. Cunningham HC, Orr S, Murugesh DK, Hsia AW, Osipov B, Go L, Wu PH, Wong A, Loots GG, Kazakia GJ, Christiansen BA. PMID: 36529445; PMCID: PMC10077944.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor. PLoS One. 2022; 17(10):e0271776. Brashear SE, Wohlgemuth RP, Hu LY, Jbeily EH, Christiansen BA, Smith LR. PMID: 36302059; PMCID: PMC9612445.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    19. Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis. Front Immunol. 2022; 13:938075. Sebastian A, Hum NR, McCool JL, Wilson SP, Murugesh DK, Martin KA, Rios-Arce ND, Amiri B, Christiansen BA, Loots GG. PMID: 35967299; PMCID: PMC9373730.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    20. Autologous regeneration of blood vessels in urinary bladder matrices provides early perfusion after transplant to the bladder. J Tissue Eng Regen Med. 2022 08; 16(8):718-731. Osborn SL, Mah LW, Ely EV, Ana S, Huynh C, Ujagar NS, Chan SC, Hsiao P, Hu JC, Chan YY, Christiansen BA, Kurzrock EA. PMID: 35567775.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    21. Preexisting Type 1 Diabetes Mellitus Blunts the Development of Posttraumatic Osteoarthritis. JBMR Plus. 2022 May; 6(5):e10625. Rios-Arce ND, Murugesh DK, Hum NR, Sebastian A, Jbeily EH, Christiansen BA, Loots GG. PMID: 35509635; PMCID: PMC9059474.
      View in: PubMed   Mentions: 6  
    22. Post-traumatic osteoarthritis progression is diminished by early mechanical unloading and anti-inflammatory treatment in mice. Osteoarthritis Cartilage. 2021 12; 29(12):1709-1719. Hsia AW, Jbeily EH, Mendez ME, Cunningham HC, Biris KK, Bang H, Lee CA, Loots GG, Christiansen BA. PMID: 34653605; PMCID: PMC8678362.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    23. Hyaluronic Acid-Binding, Anionic, Nanoparticles Inhibit ECM Degradation and Restore Compressive Stiffness in Aggrecan-Depleted Articular Cartilage Explants. Pharmaceutics. 2021 Sep 18; 13(9). Deloney M, Garoosi P, Dartora VFC, Christiansen BA, Panitch A. PMID: 34575579; PMCID: PMC8469381.
      View in: PubMed   Mentions: 4  
    24. Altered canalicular remodeling associated with femur fracture in mice. J Orthop Res. 2022 04; 40(4):891-900. Emami AJ, Sebastian A, Lin YY, Yee CS, Osipov B, Loots GG, Alliston T, Christiansen BA. PMID: 34129247; PMCID: PMC8671555.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Sex differences in systemic bone and muscle loss following femur fracture in mice. J Orthop Res. 2022 04; 40(4):878-890. Osipov B, Paralkar MP, Emami AJ, Cunningham HC, Tjandra PM, Pathak S, Langer HT, Baar K, Christiansen BA. PMID: 34081357; PMCID: PMC8639826.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    26. Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes. Cells. 2021 06 10; 10(6). Sebastian A, McCool JL, Hum NR, Murugesh DK, Wilson SP, Christiansen BA, Loots GG. PMID: 34200880; PMCID: PMC8230441.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    27. Systemic bone loss following myocardial infarction in mice. J Orthop Res. 2021 04; 39(4):739-749. Tjandra PM, Paralkar MP, Osipov B, Chen YJ, Zhao F, Ripplinger CM, Christiansen BA. PMID: 32965732; PMCID: PMC8218775.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    28. The Role of Nerves in Skeletal Development, Adaptation, and Aging. Front Endocrinol (Lausanne). 2020; 11:646. Tomlinson RE, Christiansen BA, Giannone AA, Genetos DC. PMID: 33071963; PMCID: PMC7538664.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    29. Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice. Int J Mol Sci. 2020 Sep 03; 21(17). Mendez ME, Murugesh DK, Sebastian A, Hum NR, McCloy SA, Kuhn EA, Christiansen BA, Loots GG. PMID: 32899361; PMCID: PMC7503363.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    30. LPS-Induced Inflammation Prior to Injury Exacerbates the Development of Post-Traumatic Osteoarthritis in Mice. J Bone Miner Res. 2020 11; 35(11):2229-2241. Mendez ME, Sebastian A, Murugesh DK, Hum NR, McCool JL, Hsia AW, Christiansen BA, Loots GG. PMID: 32564401; PMCID: PMC7689775.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    31. Region-dependent bone loss in the lumbar spine following femoral fracture in mice. Bone. 2020 11; 140:115555. Ely EV, Osipov B, Emami AJ, Christiansen BA. PMID: 32736144; PMCID: PMC7502487.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    32. Thermoresponsive, hollow, degradable core-shell nanoparticles for intra-articular delivery of anti-inflammatory peptide. J Control Release. 2020 07 10; 323:47-58. Deloney M, Smart K, Christiansen BA, Panitch A. PMID: 32278830; PMCID: PMC9930616.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    33. Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice. Int J Mol Sci. 2020 Jan 06; 21(1). Sebastian A, Murugesh DK, Mendez ME, Hum NR, Rios-Arce ND, McCool JL, Christiansen BA, Loots GG. PMID: 31935848; PMCID: PMC6982134.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    34. Acute Changes in NADPH Oxidase 4 in Early Post-Traumatic Osteoarthritis. J Orthop Res. 2019 11; 37(11):2429-2436. Wegner AM, Campos NR, Robbins MA, Haddad AF, Cunningham HC, Yik JHN, Christiansen BA, Haudenschild DR. PMID: 31304988; PMCID: PMC6822680.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    35. InternalBrace has biomechanical properties comparable to suture button but less rigid than screw in ligamentous lisfranc model. J Orthop. 2020 Jan-Feb; 17:7-12. Hopkins J, Nguyen K, Heyrani N, Shelton T, Kreulen C, Garcia-Nolen T, Christiansen BA, Giza E. PMID: 31879465; PMCID: PMC6919361.
      View in: PubMed   Mentions: 5  
    36. The importance of performing knee surgery in rats. Osteoarthritis Cartilage. 2019 08; 27(8):1107-1108. Christiansen BA. PMID: 31034922.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    37. Systemic Bone Loss After Fracture. Clin Rev Bone Miner Metab. 2018 Dec; 16(4):116-130. Osipov B, Emami AJ, Christiansen BA. PMID: 31363348; PMCID: PMC6667184.
      View in: PubMed   Mentions: 13  
    38. Age Dependence of Systemic Bone Loss and Recovery Following Femur Fracture in Mice. J Bone Miner Res. 2019 01; 34(1):157-170. Emami AJ, Toupadakis CA, Telek SM, Fyhrie DP, Yellowley CE, Christiansen BA. PMID: 30189111; PMCID: PMC6526937.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    39. Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression. Int J Mol Sci. 2018 Sep 07; 19(9). Sebastian A, Chang JC, Mendez ME, Murugesh DK, Hatsell S, Economides AN, Christiansen BA, Loots GG. PMID: 30205482; PMCID: PMC6163882.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    40. Age-dependent bone loss and recovery during hindlimb unloading and subsequent reloading in rats. BMC Musculoskelet Disord. 2018 Jul 18; 19(1):223. Cunningham HC, West DWD, Baehr LM, Tarke FD, Baar K, Bodine SC, Christiansen BA. PMID: 30021585; PMCID: PMC6052521.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    41. Incident fracture is associated with a period of accelerated loss of hip BMD: the Study of Osteoporotic Fractures. Osteoporos Int. 2018 Oct; 29(10):2201-2209. Christiansen BA, Harrison SL, Fink HA, Lane NE, Study of Osteoporotic Fractures Research Group. PMID: 29992510; PMCID: PMC6553454.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    42. Comparison of knee injury threshold during tibial compression based on limb orientation in mice. J Biomech. 2018 06 06; 74:220-224. Hsia AW, Tarke FD, Shelton TJ, Tjandra PM, Christiansen BA. PMID: 29678417; PMCID: PMC5962436.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury. J Bone Miner Res. 2018 06; 33(6):1105-1113. Chang JC, Christiansen BA, Murugesh DK, Sebastian A, Hum NR, Collette NM, Hatsell S, Economides AN, Blanchette CD, Loots GG. PMID: 29377313; PMCID: PMC6033030.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    44. Osteophytes and fracture calluses share developmental milestones and are diminished by unloading. J Orthop Res. 2018 02; 36(2):699-710. Hsia AW, Emami AJ, Tarke FD, Cunningham HC, Tjandra PM, Wong A, Christiansen BA, Collette NM. PMID: 29058776; PMCID: PMC5877458.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    45. Bone adaptation to mechanical loading in a mouse model of reduced peripheral sensory nerve function. PLoS One. 2017; 12(10):e0187354. Heffner MA, Genetos DC, Christiansen BA. PMID: 29088267; PMCID: PMC5663494.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    46. Achieving interfragmentary compression without special drilling technique or screw design. J Orthop Res. 2018 04; 36(4):1099-1105. Eastman J, Deafenbaugh B, Christiansen B, Garcia-Nolen T, Lee M. PMID: 28885726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. The mechanism of thoracolumbar burst fracture may be related to the basivertebral foramen. Spine J. 2018 03; 18(3):472-481. Zhang X, Li S, Zhao X, Christiansen BA, Chen J, Fan S, Zhao F. PMID: 28823938.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Trabecular Microstructure and Damage Affect Cement Leakage From the Basivertebral Foramen During Vertebral Augmentation. Spine (Phila Pa 1976). 2017 Aug 15; 42(16):E939-E948. Li S, Wang C, Shan Z, Liu J, Yu T, Zhang X, Fan S, Christiansen BA, Ding W, Zhao F. PMID: 28098744.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    49. Corrigendum to "Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis" [J. Autoimmun. 73C (2016) 73-84]. J Autoimmun. 2017 11; 84:132. Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Zarbalis KS, Adamopoulos IE. PMID: 28757133.
      View in: PubMed   Mentions:    Fields:    
    50. Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis. J Autoimmun. 2016 09; 73:73-84. Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Adamopoulos IE. PMID: 27330028; PMCID: PMC5003737.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    51. Effect of micro-computed tomography voxel size and segmentation method on trabecular bone microstructure measures in mice. Bone Rep. 2016 Dec; 5:136-40. Christiansen BA. PMID: 27430011; PMCID: PMC4926804.
      View in: PubMed   Mentions: 35  
    52. Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis. J Orthop Res. 2017 03; 35(3):474-485. Chang JC, Sebastian A, Murugesh DK, Hatsell S, Economides AN, Christiansen BA, Loots GG. PMID: 27088242; PMCID: PMC5363336.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    53. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells. Bone. 2016 07; 88:20-30. Collette NM, Yee CS, Hum NR, Murugesh DK, Christiansen BA, Xie L, Economides AN, Manilay JO, Robling AG, Loots GG. PMID: 27102547; PMCID: PMC6277141.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    54. Osteophyte formation after ACL rupture in mice is associated with joint restabilization and loss of range of motion. J Orthop Res. 2017 03; 35(3):466-473. Hsia AW, Anderson MJ, Heffner MA, Lagmay EP, Zavodovskaya R, Christiansen BA. PMID: 27031945; PMCID: PMC5603200.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    55. Contribution of mechanical unloading to trabecular bone loss following non-invasive knee injury in mice. J Orthop Res. 2016 10; 34(10):1680-1687. Anderson MJ, Diko S, Baehr LM, Baar K, Bodine SC, Christiansen BA. PMID: 26826014; PMCID: PMC5603199.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    56. Erratum: Response to the Letter to the Editor for "Management of Osteoarthritis with Avocado/Soybean Unsaponifiables". Cartilage. 2016 Jan; 7(1):114-5. Christiansen BA, Bhatti S, Goudarzi R, Emami S. PMID: 26958324; PMCID: PMC4749756.
      View in: PubMed   Mentions: 1     Fields:    
    57. SOST Inhibits Prostate Cancer Invasion. PLoS One. 2015; 10(11):e0142058. Hudson BD, Hum NR, Thomas CB, Kohlgruber A, Sebastian A, Collette NM, Coleman MA, Christiansen BA, Loots GG. PMID: 26545120; PMCID: PMC4636315.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    58. BMP-7 and Bone Regeneration: Evaluation of Dose-Response in a Rodent Segmental Defect Model. J Orthop Trauma. 2015 Sep; 29(9):e336-41. Williams JC, Maitra S, Anderson MJ, Christiansen BA, Reddi AH, Lee MA. PMID: 26295737.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    59. Non-invasive mouse models of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2015 Oct; 23(10):1627-38. Christiansen BA, Guilak F, Lockwood KA, Olson SA, Pitsillides AA, Sandell LJ, Silva MJ, van der Meulen MC, Haudenschild DR. PMID: 26003950; PMCID: PMC4577460.
      View in: PubMed   Mentions: 61     Fields:    Translation:Animals
    60. Bone Material Properties and Skeletal Fragility. Calcif Tissue Int. 2015 Sep; 97(3):213-28. Fyhrie DP, Christiansen BA. PMID: 25939648.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    61. Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice. Arthritis Res Ther. 2015 Feb 16; 17:30. Khorasani MS, Diko S, Hsia AW, Anderson MJ, Genetos DC, Haudenschild DR, Christiansen BA. PMID: 25888819; PMCID: PMC4355375.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    62. Trabecular bone loss at a distant skeletal site following noninvasive knee injury in mice. J Biomech Eng. 2015 Jan; 137(1). Christiansen BA, Emami AJ, Fyhrie DP, Satkunananthan PB, Hardisty MR. PMID: 25322065; PMCID: PMC4296239.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    63. Closed Joint ACL Disruption Murine Model of PTA. . 2015 Jan 1; 75-85. Christiansen CB, Yik YJ, Haudenschild HD. .
      View in: Publisher Site   Mentions:
    64. Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. Cartilage. 2015 Jan; 6(1):30-44. Christiansen BA, Bhatti S, Goudarzi R, Emami S. PMID: 25621100; PMCID: PMC4303902.
      View in: PubMed   Mentions: 28     Fields:    
    65. Trabecular bone: light as a feather, stiff as a board. J Biomech Eng. 2015 Jan; 137(1). Nazarian A, Christiansen BA. PMID: 25408309.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    66. In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2014 Oct; 22(10):1461-9. Satkunananthan PB, Anderson MJ, De Jesus NM, Haudenschild DR, Ripplinger CM, Christiansen BA. PMID: 25278057; PMCID: PMC4185155.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    67. Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines. Arthritis Rheumatol. 2014 Jun; 66(6):1537-46. Yik JH, Hu Z, Kumari R, Christiansen BA, Haudenschild DR. PMID: 24470357; PMCID: PMC4127300.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    68. The effect of noggin interference in a rabbit posterolateral spinal fusion model. Eur Spine J. 2014 Nov; 23(11):2385-92. Klineberg E, Haudenschild DR, Snow KD, Garitty S, Christiansen BA, Acharya C, Maitra S, Gupta MC. PMID: 24740279.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    69. Altered bone development in a mouse model of peripheral sensory nerve inactivation. J Musculoskelet Neuronal Interact. 2014 Mar; 14(1):1-9. Heffner MA, Anderson MJ, Yeh GC, Genetos DC, Christiansen BA. PMID: 24583535; PMCID: PMC4123540.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    70. Remineralized bone matrix as a scaffold for bone tissue engineering. J Biomed Mater Res A. 2014 Dec; 102(12):4480-90. Soicher MA, Christiansen BA, Stover SM, Leach JK, Yellowley CE, Griffiths LG, Fyhrie DP. PMID: 24616346; PMCID: PMC4145060.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    71. Locking versus nonlocking construct in an osteoporotic, segmental fibula defect model. Orthopedics. 2013 Oct 01; 36(10):e1262-8. Lo EY, Tseng SS, Christiansen BA, Lee MA, Yoo BJ. PMID: 24093701.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    72. Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis. J Orthop Res. 2014 Jan; 32(1):79-88. Lockwood KA, Chu BT, Anderson MJ, Haudenschild DR, Christiansen BA. PMID: 24019199; PMCID: PMC4140447.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    73. Assessment of Bone Mass and Microarchitecture in Rodents. . 2013 Jul 19; 59-68. Christiansen CB. .
      View in: Publisher Site   Mentions:
    74. Remineralization of demineralized bone matrix (DBM) via alternating solution immersion (ASI). J Mech Behav Biomed Mater. 2013 Oct; 26:109-18. Soicher MA, Christiansen BA, Stover SM, Leach JK, Fyhrie DP. PMID: 23759125; PMCID: PMC3713112.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    75. Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass. J Bone Miner Res. 2013 Apr; 28(4):875-85. Ellman R, Spatz J, Cloutier A, Palme R, Christiansen BA, Bouxsein ML. PMID: 23165526; PMCID: PMC4118556.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    76. Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2. Bone. 2013 Jul; 55(1):23-35. Ishida K, Acharya C, Christiansen BA, Yik JH, DiCesare PE, Haudenschild DR. PMID: 23528838.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    77. Mechanical and morphological properties of trabecular bone samples obtained from third metacarpal bones of cadavers of horses with a bone fragility syndrome and horses unaffected by that syndrome. Am J Vet Res. 2012 Nov; 73(11):1742-51. Symons JE, Entwistle RC, Arens AM, Garcia TC, Christiansen BA, Fyhrie DP, Stover SM. PMID: 23106459.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    78. Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair. J Orthop Res. 2012 Nov; 30(11):1853-9. Toupadakis CA, Wong A, Genetos DC, Chung DJ, Murugesh D, Anderson MJ, Loots GG, Christiansen BA, Kapatkin AS, Yellowley CE. PMID: 22592891; PMCID: PMC3704138.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    79. Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2012 Jul; 20(7):773-82. Christiansen BA, Anderson MJ, Lee CA, Williams JC, Yik JH, Haudenschild DR. PMID: 22531459.
      View in: PubMed   Mentions: 105     Fields:    Translation:Animals
    80. QCT measures of bone strength at the thoracic and lumbar spine: the Framingham Study. J Bone Miner Res. 2012 Mar; 27(3):654-63. Samelson EJ, Christiansen BA, Demissie S, Broe KE, Louie-Gao Q, Cupples LA, Roberts BJ, Manoharam R, D'Agostino J, Lang T, Kiel DP, Bouxsein ML. PMID: 22143959; PMCID: PMC3728822.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    81. Mechanical contributions of the cortical and trabecular compartments contribute to differences in age-related changes in vertebral body strength in men and women assessed by QCT-based finite element analysis. J Bone Miner Res. 2011 May; 26(5):974-83. Christiansen BA, Kopperdahl DL, Kiel DP, Keaveny TM, Bouxsein ML. PMID: 21542000; PMCID: PMC3179306.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    82. Biomechanics of vertebral fractures and the vertebral fracture cascade. Curr Osteoporos Rep. 2010 Dec; 8(4):198-204. Christiansen BA, Bouxsein ML. PMID: 20838942.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    83. A biomechanical model for estimating loads on thoracic and lumbar vertebrae. Clin Biomech (Bristol, Avon). 2010 Nov; 25(9):853-8. Iyer S, Christiansen BA, Roberts BJ, Valentine MJ, Manoharan RK, Bouxsein ML. PMID: 20655634; PMCID: PMC2949493.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    84. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 2010 Jul; 25(7):1468-86. Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. PMID: 20533309.
      View in: PubMed   Mentions: 1948     Fields:    Translation:Animals
    85. Reliability of vertebral fracture assessment using multidetector CT lateral scout views: the Framingham Osteoporosis Study. Osteoporos Int. 2011 Apr; 22(4):1123-31. Samelson EJ, Christiansen BA, Demissie S, Broe KE, Zhou Y, Meng CA, Yu W, Cheng X, O'Donnell CJ, Hoffmann U, Genant HK, Kiel DP, Bouxsein ML. PMID: 20495902; PMCID: PMC2964444.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    86. Constrained tibial vibration does not produce an anabolic bone response in adult mice. Bone. 2009 Oct; 45(4):750-9. Christiansen BA, Kotiya AA, Silva MJ. PMID: 19576309; PMCID: PMC2774766.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    87. A New Biomechanical Model for Estimating Vertebral Loading in the Thoracic Spine. . 2009 Jun 17; 1129-1130. Iyer IS, Christiansen CB, Roberts RB, Valentine VM, Manoharan MR, Bouxsein BM. .
      View in: Publisher Site   Mentions:
    88. Whole-body vibration and weight loss: truth or consequence? Int J Obes (Lond). 2009 Mar; 33(3):384; author reply 382-3. Christiansen BA. PMID: 19153586.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    89. Constrained tibial vibration in mice: a method for studying the effects of vibrational loading of bone. J Biomech Eng. 2008 Aug; 130(4):044502. Christiansen BA, Bayly PV, Silva MJ. PMID: 18601464; PMCID: PMC2893880.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    90. Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice. Am J Pathol. 2008 Apr; 172(4):868-81. Ramanadham S, Yarasheski KE, Silva MJ, Wohltmann M, Novack DV, Christiansen B, Tu X, Zhang S, Lei X, Turk J. PMID: 18349124; PMCID: PMC2276416.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    91. The effect of varying magnitudes of whole-body vibration on several skeletal sites in mice. Ann Biomed Eng. 2006 Jul; 34(7):1149-56. Christiansen BA, Silva MJ. PMID: 16786394.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
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