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Clare Yellowley

Title(s)Associate Professor, Anatomy, Physiology and Cell Biology
Phone530-754-6513
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yellowley CE, Genetos DC. Hypoxia Signaling in the Skeleton: Implications for Bone Health. Curr Osteoporos Rep. 2019 Feb 06. PMID: 30725321.
      View in: PubMed
    2. Emami AJ, Toupadakis CA, Telek SM, Fyhrie DP, Yellowley CE, Christiansen BA. Age Dependence of Systemic Bone Loss and Recovery Following Femur Fracture in Mice. J Bone Miner Res. 2018 Sep 06. PMID: 30189111.
      View in: PubMed
    3. Loots GG, Robling AG, Chang JC, Murugesh DK, Bajwa J, Carlisle C, Manilay JO, Wong A, Yellowley CE, Genetos DC. Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects. Bone. 2018 Nov; 116:307-314. PMID: 30172741.
      View in: PubMed
    4. Wilson SS, Wong A, Toupadakis CA, Yellowley CE. Expression of angiopoietin-like protein 4 at the fracture site: Regulation by hypoxia and osteoblastic differentiation. J Orthop Res. 2015 Sep; 33(9):1364-73. PMID: 25864912.
      View in: PubMed
    5. Wong A, Loots GG, Yellowley CE, Dosé AC, Genetos DC. Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells. Bone. 2015 Dec; 81:97-103. PMID: 26151122.
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    6. Kilgallon CP, Larsen S, Wong A, Yellowley C. Analysis of a collagen II degradation protein C2C and a collagen II formation protein CP II in serum of Asian elephants (Elephas maximus). J Zoo Wildl Med. 2015 Mar; 46(1):146-9. PMID: 25831589.
      View in: PubMed
    7. Genetos DC, Wong A, Weber TJ, Karin NJ, Yellowley CE. Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells. PLoS One. 2014; 9(9):e107482. PMID: 25222280; PMCID: PMC4164658.
      View in: PubMed, PubMed Central
    8. Wong A, Ghassemi E, Yellowley CE. Nestin expression in mesenchymal stromal cells: regulation by hypoxia and osteogenesis. BMC Vet Res. 2014 Aug 05; 10:173. PMID: 25088159; PMCID: PMC4236815.
      View in: PubMed, PubMed Central
    9. Soicher MA, Christiansen BA, Stover SM, Leach JK, Yellowley CE, Griffiths LG, Fyhrie DP. Remineralized bone matrix as a scaffold for bone tissue engineering. J Biomed Mater Res A. 2014 Dec; 102(12):4480-90. PMID: 24616346; PMCID: PMC4145060.
      View in: PubMed, PubMed Central
    10. Chung DJ, Wong A, Hayashi K, Yellowley CE. Effect of hypoxia on generation of neurospheres from adipose tissue-derived canine mesenchymal stromal cells. Vet J. 2014 Jan; 199(1):123-30. PMID: 24252224.
      View in: PubMed
    11. Bhandal J, Hayashi K, Kim SY, Klein M, Wong A, Toupadakis CA, Muir P, Yellowley CE. Detection of bacterial DNA by PCR in dogs with stifle pathology. Vet Surg. 2013 Oct; 42(7):814-8. PMID: 24033641.
      View in: PubMed
    12. Toupadakis CA, Granick JL, Sagy M, Wong A, Ghassemi E, Chung DJ, Borjesson DL, Yellowley CE. Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model. Cytotherapy. 2013 Sep; 15(9):1136-47. PMID: 23831362.
      View in: PubMed
    13. Yellowley C. CXCL12/CXCR4 signaling and other recruitment and homing pathways in fracture repair. Bonekey Rep. 2013 Mar 13; 2:300. PMID: 24422056; PMCID: PMC3722739.
      View in: PubMed, PubMed Central
    14. Toupadakis CA, Wong A, Genetos DC, Chung DJ, Murugesh D, Anderson MJ, Loots GG, Christiansen BA, Kapatkin AS, Yellowley CE. Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair. J Orthop Res. 2012 Nov; 30(11):1853-9. PMID: 22592891.
      View in: PubMed
    15. Morgan JM, Wong A, Yellowley CE, Genetos DC. Regulation of tenascin expression in bone. J Cell Biochem. 2011 Nov; 112(11):3354-63. PMID: 21751239; PMCID: PMC3196820.
      View in: PubMed, PubMed Central
    16. Raheja LF, Genetos DC, Wong A, Yellowley CE. Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1a. Cell Biol Int. 2011 Oct; 35(10):981-9. PMID: 21574962.
      View in: PubMed
    17. Genetos DC, Yellowley CE, Loots GG. Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression. PLoS One. 2011 Mar 16; 6(3):e17772. PMID: 21436889; PMCID: PMC3059227.
      View in: PubMed, PubMed Central
    18. Morgan JM, Wong A, Genetos DC, Yellowley CE. Src is sufficient, but not necessary, for osteopontin induction in osteoblasts. Biorheology. 2011; 48(1):65-74. PMID: 21515937.
      View in: PubMed
    19. Chung DJ, Hayashi K, Toupadakis CA, Wong A, Yellowley CE. Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia. Res Vet Sci. 2012 Feb; 92(1):66-75. PMID: 21075407.
      View in: PubMed
    20. Toupadakis CA, Wong A, Genetos DC, Cheung WK, Borjesson DL, Ferraro GL, Galuppo LD, Leach JK, Owens SD, Yellowley CE. Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood, and umbilical cord tissue. Am J Vet Res. 2010 Oct; 71(10):1237-45. PMID: 20919913.
      View in: PubMed
    21. Genetos DC, Wong A, Watari S, Yellowley CE. Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK. Bone. 2010 Dec; 47(6):1013-9. PMID: 20817051; PMCID: PMC4420171.
      View in: PubMed, PubMed Central
    22. Genetos DC, Toupadakis CA, Raheja LF, Wong A, Papanicolaou SE, Fyhrie DP, Loots GG, Yellowley CE. Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts. J Cell Biochem. 2010 May 15; 110(2):457-67. PMID: 20336693; PMCID: PMC2881162.
      View in: PubMed, PubMed Central
    23. He J, Genetos DC, Yellowley CE, Leach JK. Oxygen tension differentially influences osteogenic differentiation of human adipose stem cells in 2D and 3D cultures. J Cell Biochem. 2010 May; 110(1):87-96. PMID: 20213746.
      View in: PubMed
    24. Raheja LF, Genetos DC, Yellowley CE. The effect of oxygen tension on the long-term osteogenic differentiation and MMP/TIMP expression of human mesenchymal stem cells. Cells Tissues Organs. 2010; 191(3):175-84. PMID: 19690399.
      View in: PubMed
    25. Lee CM, Genetos DC, Wong A, Yellowley CE. Prostaglandin expression profile in hypoxic osteoblastic cells. J Bone Miner Metab. 2010; 28(1):8-16. PMID: 19471853.
      View in: PubMed
    26. Genetos DC, Lee CM, Wong A, Yellowley CE. HIF-1alpha regulates hypoxia-induced EP1 expression in osteoblastic cells. J Cell Biochem. 2009 May 15; 107(2):233-9. PMID: 19277991; PMCID: PMC4410710.
      View in: PubMed, PubMed Central
    27. Raheja LF, Genetos DC, Yellowley CE. Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):1061-6. PMID: 18155656.
      View in: PubMed
    28. Russell JM, Stephenson GS, Yellowley CE, Benton HP. Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63. Calcif Tissue Int. 2007 Oct; 81(4):316-26. PMID: 17705048.
      View in: PubMed
    29. Waters KM, Tan R, Genetos DC, Verma S, Yellowley CE, Karin NJ. DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells. Bone. 2007 Nov; 41(5):833-41. PMID: 17719864.
      View in: PubMed
    30. Lee CM, Genetos DC, You Z, Yellowley CE. Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells. J Cell Physiol. 2007 Jul; 212(1):182-8. PMID: 17370287; PMCID: PMC2929130.
      View in: PubMed, PubMed Central
    31. Genetos DC, Kephart CJ, Zhang Y, Yellowley CE, Donahue HJ. Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes. J Cell Physiol. 2007 Jul; 212(1):207-14. PMID: 17301958; PMCID: PMC2929812.
      View in: PubMed, PubMed Central
    32. Kim CH, You L, Yellowley CE, Jacobs CR. Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling. Bone. 2006 Nov; 39(5):1043-1047. PMID: 16860618.
      View in: PubMed
    33. Batra NN, Li YJ, Yellowley CE, You L, Malone AM, Kim CH, Jacobs CR. Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. J Biomech. 2005 Sep; 38(9):1909-17. PMID: 16023480.
      View in: PubMed
    34. Li YJ, Batra NN, You L, Meier SC, Coe IA, Yellowley CE, Jacobs CR. Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. J Orthop Res. 2004 Nov; 22(6):1283-9. PMID: 15475210.
      View in: PubMed
    35. Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells. Bone. 2004 Sep; 35(3):656-63. PMID: 15336601.
      View in: PubMed
    36. Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Cycle number and waveform of fluid flow affect bovine articular chondrocytes. Biorheology. 2004; 41(3-4):315-22. PMID: 15299264.
      View in: PubMed
    37. Alford AI, Yellowley CE, Jacobs CR, Donahue HJ. Increases in cytosolic calcium, but not fluid flow, affect aggrecan mRNA levels in articular chondrocytes. J Cell Biochem. 2003 Dec 01; 90(5):938-44. PMID: 14624453.
      View in: PubMed
    38. Donahue TL, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport. J Biomech. 2003 Sep; 36(9):1363-71. PMID: 12893045.
      View in: PubMed
    39. Saunders MM, You J, Zhou Z, Li Z, Yellowley CE, Kunze EL, Jacobs CR, Donahue HJ. Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium. Bone. 2003 Apr; 32(4):350-6. PMID: 12689677.
      View in: PubMed
    40. Reilly GC, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. Biorheology. 2003; 40(6):591-603. PMID: 14610310.
      View in: PubMed
    41. Sharma R, Yellowley CE, Civelek M, Ainslie K, Hodgson L, Tarbell JM, Donahue HJ. Intracellular calcium changes in rat aortic smooth muscle cells in response to fluid flow. Ann Biomed Eng. 2002 Mar; 30(3):371-8. PMID: 12051621; PMCID: PMC4472337.
      View in: PubMed, PubMed Central
    42. Yellowley CE, Hancox JC, Donahue HJ. Effects of cell swelling on intracellular calcium and membrane currents in bovine articular chondrocytes. J Cell Biochem. 2002; 86(2):290-301. PMID: 12111998.
      View in: PubMed
    43. Guo Y, Martinez-Williams C, Yellowley CE, Donahue HJ, Rannels DE. Connexin expression by alveolar epithelial cells is regulated by extracellular matrix. Am J Physiol Lung Cell Mol Physiol. 2001 Feb; 280(2):L191-202. PMID: 11158997.
      View in: PubMed
    44. You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR. Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem. 2001 Apr 20; 276(16):13365-71. PMID: 11278573.
      View in: PubMed
    45. Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates cytosolic calcium concentration in bovine articular chondrocytes. J Biomech. 2001 Jan; 34(1):59-65. PMID: 11425081.
      View in: PubMed
    46. You J, Yellowley CE, Donahue HJ, Zhang Y, Chen Q, Jacobs CR. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow. J Biomech Eng. 2000 Aug; 122(4):387-93. PMID: 11036562.
      View in: PubMed
    47. Yellowley CE, Li Z, Zhou Z, Jacobs CR, Donahue HJ. Functional gap junctions between osteocytic and osteoblastic cells. J Bone Miner Res. 2000 Feb; 15(2):209-17. PMID: 10703922.
      View in: PubMed
    48. Donahue HJ, Li Z, Zhou Z, Yellowley CE. Differentiation of human fetal osteoblastic cells and gap junctional intercellular communication. Am J Physiol Cell Physiol. 2000 Feb; 278(2):C315-22. PMID: 10666026.
      View in: PubMed
    49. Jacobs CR, Yellowley CE, Nelson DV, Donahue HJ. Analysis of Time-Varying Biological Data Using Rainflow Cycle Counting. Comput Methods Biomech Biomed Engin. 2000; 3(1):31-40. PMID: 11264837.
      View in: PubMed
    50. Li Z, Zhou Z, Yellowley CE, Donahue HJ. Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells. Bone. 1999 Dec; 25(6):661-6. PMID: 10593410.
      View in: PubMed
    51. Yellowley CE, Jacobs CR, Donahue HJ. Mechanisms contributing to fluid-flow-induced Ca2+ mobilization in articular chondrocytes. J Cell Physiol. 1999 Sep; 180(3):402-8. PMID: 10430180.
      View in: PubMed
    52. Jacobs CR, Yellowley CE, Davis BR, Zhou Z, Cimbala JM, Donahue HJ. Differential effect of steady versus oscillating flow on bone cells. J Biomech. 1998 Nov; 31(11):969-76. PMID: 9880053; PMCID: PMC3057628.
      View in: PubMed, PubMed Central
    53. Yellowley CE, Hancox JC, Skerry TM, Levi AJ. Whole-cell membrane currents from human osteoblast-like cells. Calcif Tissue Int. 1998 Feb; 62(2):122-32. PMID: 9437045.
      View in: PubMed
    54. Yellowley CE, Jacobs CR, Li Z, Zhou Z, Donahue HJ. Effects of fluid flow on intracellular calcium in bovine articular chondrocytes. Am J Physiol. 1997 Jul; 273(1 Pt 1):C30-6. PMID: 9252439.
      View in: PubMed
    55. Lee YC, Yellowley CE, Li Z, Donahue HJ, Rannels DE. Expression of functional gap junctions in cultured pulmonary alveolar epithelial cells. Am J Physiol. 1997 Jun; 272(6 Pt 1):L1105-14. PMID: 9227511.
      View in: PubMed
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