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Pathogenesis of psoriatic arthritis: new insights from a bone marrow perspective. Curr Opin Rheumatol. 2024 Oct 30.
Saeed F, Adamopoulos IE. PMID: 39470182.
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PubMed Mentions:
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IL-23 induces CLEC5A+ IL-17A+ neutrophils and elicit skin inflammation associated with psoriatic arthritis. J Autoimmun. 2024 02; 143:103167.
Furuya H, Nguyen CT, Chan T, Marusina AI, Merleev AA, Garcia-Hernandez ML, Hsieh SL, Tsokos GC, Ritchlin CT, Tagkopoulos I, Maverakis E, Adamopoulos IE. PMID: 38301504; PMCID: PMC10981569.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Innate immune memory in inflammatory arthritis. Nat Rev Rheumatol. 2023 10; 19(10):627-639.
Jeljeli MM, Adamopoulos IE. PMID: 37674048; PMCID: PMC10721491.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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IL-17A and IL-17F in tissue homeostasis, inflammation and regeneration. Nat Rev Rheumatol. 2023 09; 19(9):535-536.
Adamopoulos IE, Kuchroo V. PMID: 37488297; PMCID: PMC10709714.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Interleukin-23 Regulates Inflammatory Osteoclastogenesis via Activation of CLEC5A(+) Osteoclast Precursors. Arthritis Rheumatol. 2023 08; 75(8):1477-1489.
Furuya H, Nguyen CT, Gu R, Hsieh SL, Maverakis E, Adamopoulos IE. PMID: 36787107; PMCID: PMC10423744.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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IL-27 attenuates IL-23 mediated inflammatory arthritis. Clin Immunol. 2023 06; 251:109327.
Sarin R, Gu R, Jalali Z, Maverakis E, Tsokos MG, Adamopoulos IE. PMID: 37037268; PMCID: PMC10205692.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Autophagy pathways in autoimmune diseases. J Autoimmun. 2023 04; 136:103030.
Keller CW, Adamopoulos IE, Lünemann JD. PMID: 37001435; PMCID: PMC10709713.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis. J Invest Dermatol. 2023 07; 143(7):1157-1167.e10.
Marusina AI, Ji-Xu A, Le ST, Toussi A, Tsoi LC, Li Q, Luxardi G, Nava J, Downing L, Leal AR, Kuzminykh NY, Kruglinskaya O, Brüggen MC, Adamopoulos IE, Merleev AA, Gudjonsson JE, Maverakis E. PMID: 36716917.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G. JCI Insight. 2022 08 22; 7(16).
Merleev A, Ji-Xu A, Toussi A, Tsoi LC, Le ST, Luxardi G, Xing X, Wasikowski R, Liakos W, Brüggen MC, Elder JT, Adamopoulos IE, Izumiya Y, Leal AR, Li Q, Kuzminykh NY, Kirane A, Marusina AI, Gudjonsson JE, Maverakis E. PMID: 35862195; PMCID: PMC9462487.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes. JCI Insight. 2022 08 22; 7(16).
Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E. PMID: 35900871; PMCID: PMC9462509.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Peripheral γδ T Cells Regulate Neutrophil Expansion and Recruitment in Experimental Psoriatic Arthritis. Arthritis Rheumatol. 2022 09; 74(9):1524-1534.
Nguyen CT, Furuya H, Das D, Marusina AI, Merleev AA, Ravindran R, Jalali Z, Khan IH, Maverakis E, Adamopoulos IE. PMID: 35320625; PMCID: PMC9427669.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Serine and arginine rich splicing factor 1 deficiency alters pathways involved in IL-17A expression and is implicated in human psoriasis. Clin Immunol. 2022 07; 240:109041.
Su S, Katopodi XL, Pita-Juarez YH, Maverakis E, Vlachos IS, Adamopoulos IE. PMID: 35613697; PMCID: PMC10797199.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12).
Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. PMID: 33956666; PMCID: PMC8203450.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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IL-23 Inhibition in Ankylosing Spondylitis: Where Did It Go Wrong? Front Immunol. 2020; 11:623874.
Baeten D, Adamopoulos IE. PMID: 33679714; PMCID: PMC7935519.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, et al. PMID: 33634751; PMCID: PMC7996087.
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PubMed Mentions:
1060 Fields:
Translation:
HumansAnimalsCells
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Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities. Dermatol Ther (Heidelb). 2021 Apr; 11(2):385-400.
Menter A, Krueger GG, Paek SY, Kivelevitch D, Adamopoulos IE, Langley RG. PMID: 33512665; PMCID: PMC8019008.
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PubMed Mentions:
29
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Axial spondyloarthritis: new advances in diagnosis and management. BMJ. 2021 01 04; 372:m4447.
Ritchlin C, Adamopoulos IE. PMID: 33397652.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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A site-specific map of the human plasma glycome and its age and gender-associated alterations. Sci Rep. 2020 10 15; 10(1):17505.
Merleev AA, Park D, Xie Y, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Patel F, Wan YY, Marusina AI, Adamopoulos IE, Lal NN, Mitra A, Le ST, Shimoda M, Luxardi G, Lebrilla CB, Maverakis E. PMID: 33060657; PMCID: PMC7567094.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Psoriatic arthritis; overcoming the challenges by creating opportunities. Clin Immunol. 2020 09; 218:108519.
Bell S, Nahle Z, Adamopoulos IE. PMID: 32621978; PMCID: PMC7595648.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Psoriatic arthritis under the influence of IFNγ. Clin Immunol. 2020 09; 218:108513.
Dai H, Adamopoulos IE. PMID: 32574710; PMCID: PMC7595649.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nat Commun. 2020 06 05; 11(1):2859.
Li H, Adamopoulos IE, Moulton VR, Stillman IE, Herbert Z, Moon JJ, Sharabi A, Krishfield S, Tsokos MG, Tsokos GC. PMID: 32503973; PMCID: PMC7275084.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity. Semin Immunopathol. 2019 09; 41(5):595-605.
Nguyen CT, Maverakis E, Eberl M, Adamopoulos IE. PMID: 31506867; PMCID: PMC6815259.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells. Front Immunol. 2019; 10:589.
Le ST, Merleev AA, Luxardi G, Shimoda M, Adamopoulos IE, Tsoi LC, Wang JZ, Alexanian C, Raychaudhuri SP, Hwang ST, Gudjonsson J, Marusina AI, Maverakis E. PMID: 31019502; PMCID: PMC6458264.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Compendium of synovial signatures identifies pathologic characteristics for predicting treatment response in rheumatoid arthritis patients. Clin Immunol. 2019 05; 202:1-10.
Kim KJ, Kim M, Adamopoulos IE, Tagkopoulos I. PMID: 30831253; PMCID: PMC7605311.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Interleukin-17A and Pathologic New Bone Formation: The Myth of Prometheus Revisited. Arthritis Rheumatol. 2019 04; 71(4):483-485.
Adamopoulos IE. PMID: 30663867; PMCID: PMC6438746.
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PubMed Mentions: Fields:
Translation:
Humans
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Go with the flow-hidden vascular passages in bone. Nat Metab. 2019 Feb; 1(2):173-174.
Ritchlin C, Adamopoulos IE. PMID: 31693001; PMCID: PMC6831092.
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PubMed Mentions:
2 Fields:
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Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis: A molecular insight. Clin Immunol. 2019 09; 206:15-22.
Nguyen CT, Bloch Y, Skladanowska K, Savvides SN, Adamopoulos IE. PMID: 30196070; PMCID: PMC6401348.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A. JCI Insight. 2018 07 12; 3(13).
Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E. PMID: 29997305; PMCID: PMC6124526.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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γδTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis. Sci Rep. 2018 05 15; 8(1):7590.
Bouchareychas L, Grössinger EM, Kang M, Adamopoulos IE. PMID: 29765156; PMCID: PMC5954154.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Inflammation in bone physiology and pathology. Curr Opin Rheumatol. 2018 Jan; 30(1):59-64.
Adamopoulos IE. PMID: 29016371; PMCID: PMC5963529.
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PubMed Mentions:
63 Translation:
HumansAnimalsCells
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Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1. Immunity. 2018 01 16; 48(1):45-58.e6.
Bloch Y, Bouchareychas L, Merceron R, Skladanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN. PMID: 29287995; PMCID: PMC5773378.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis. J Immunol. 2018 01 15; 200(2):749-757.
Grössinger EM, Kang M, Bouchareychas L, Sarin R, Haudenschild DR, Borodinsky LN, Adamopoulos IE. PMID: 29246953; PMCID: PMC5815326.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Targeting IL-17 in psoriatic arthritis. Eur J Rheumatol. 2017 Dec; 4(4):272-277.
Wang EA, Suzuki E, Maverakis E, Adamopoulos IE. PMID: 29308283; PMCID: PMC5741341.
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PubMed Mentions:
19
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Corrigendum to "Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis" [J. Autoimmun. 73C (2016) 73-84]. J Autoimmun. 2017 11; 84:132.
Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Zarbalis KS, Adamopoulos IE. PMID: 28757133.
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PubMed Mentions: Fields:
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Concise Review: Stem Cells in Osteoimmunology. Stem Cells. 2017 06; 35(6):1461-1467.
Fierro FA, Nolta JA, Adamopoulos IE. PMID: 28390147; PMCID: PMC6047890.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol. 2017 06; 316:61-69.
Wu DJ, Adamopoulos IE. PMID: 28449847; PMCID: PMC5515728.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Autophagy and autoimmunity. Clin Immunol. 2017 03; 176:55-62.
Wu DJ, Adamopoulos IE. PMID: 28095319; PMCID: PMC5346336.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimals
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Critical Role of LTB4/BLT1 in IL-23-Induced Synovial Inflammation and Osteoclastogenesis via NF-κB. J Immunol. 2017 01 01; 198(1):452-460.
Bouchareychas L, Grössinger EM, Kang M, Qiu H, Adamopoulos IE. PMID: 27895169; PMCID: PMC5173389.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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CD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. J Autoimmun. 2017 02; 77:76-88.
Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E. PMID: 27894837; PMCID: PMC6066671.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia. J Immunol. 2016 12 01; 197(11):4403-4412.
Suzuki E, Maverakis E, Sarin R, Bouchareychas L, Kuchroo VK, Nestle FO, Adamopoulos IE. PMID: 27798153; PMCID: PMC5123839.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review. Clin Rev Allergy Immunol. 2016 Aug; 51(1):87-99.
Sukhov A, Adamopoulos IE, Maverakis E. PMID: 26780035; PMCID: PMC6080719.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis. J Autoimmun. 2016 09; 73:73-84.
Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Adamopoulos IE. PMID: 27330028; PMCID: PMC5003737.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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The critical role of toll-like receptors--From microbial recognition to autoimmunity: A comprehensive review. Autoimmun Rev. 2016 Jan; 15(1):1-8.
Jiménez-Dalmaroni MJ, Gerswhin ME, Adamopoulos IE. PMID: 26299984; PMCID: PMC4679489.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Autoimmune or Autoiflammatory? Bad to the Bone. Int J Clin Rheumtol. 2015; 10(1):5-7.
Adamopoulos IE. PMID: 26388947; PMCID: PMC4570489.
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PubMed Mentions:
2
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Leukotriene B4 activates intracellular calcium and augments human osteoclastogenesis. Arthritis Res Ther. 2014 Dec 02; 16(6):496.
Dixit N, Wu DJ, Belgacem YH, Borodinsky LN, Gershwin ME, Adamopoulos IE. PMID: 25443625; PMCID: PMC4276054.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Crosstalk among IL-23 and DNAX activating protein of 12 kDa-dependent pathways promotes osteoclastogenesis. J Immunol. 2015 Jan 01; 194(1):316-24.
Shin HS, Sarin R, Dixit N, Wu J, Gershwin E, Bowman EP, Adamopoulos IE. PMID: 25452564; PMCID: PMC4272876.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Alternative pathways of osteoclastogenesis in inflammatory arthritis. Nat Rev Rheumatol. 2015 Mar; 11(3):189-94.
Adamopoulos IE, Mellins ED. PMID: 25422000; PMCID: PMC4346500.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis. Liver Int. 2015 Feb; 35(2):642-51.
Norman GL, Yang CY, Ostendorff HP, Shums Z, Lim MJ, Wang J, Awad A, Hirschfield GM, Milkiewicz P, Bloch DB, Rothschild KJ, Bowlus CL, Adamopoulos IE, Leung PS, Janssen HJ, Cheung AC, Coltescu C, Gershwin ME. PMID: 25243383; PMCID: PMC4305042.
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PubMed Mentions:
32 Fields:
Translation:
HumansCTClinical Trials
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Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014 Sep 08; 5:4692.
Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS. PMID: 25198012; PMCID: PMC4159772.
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PubMed Mentions:
47 Fields:
Translation:
Animals
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A novel in vivo gene transfer technique and in vitro cell based assays for the study of bone loss in musculoskeletal disorders. J Vis Exp. 2014 Jun 08; (88).
Wu DJ, Dixit N, Suzuki E, Nguyen T, Shin HS, Davis J, Maverakis E, Adamopoulos IE. PMID: 24961167; PMCID: PMC4188139.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis. Ann Rheum Dis. 2015 Jun; 74(6):1284-92.
Adamopoulos IE, Suzuki E, Chao CC, Gorman D, Adda S, Maverakis E, Zarbalis K, Geissler R, Asio A, Blumenschein WM, Mcclanahan T, De Waal Malefyt R, Gershwin ME, Bowman EP. PMID: 24567524; PMCID: PMC4229480.
View in:
PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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The IL-23/IL-17 axis in psoriatic arthritis. Autoimmun Rev. 2014 Apr-May; 13(4-5):496-502.
Suzuki E, Mellins ED, Gershwin ME, Nestle FO, Adamopoulos IE. PMID: 24424175; PMCID: PMC3995976.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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NKG2C, HLA-E and their association with psoriasis. Exp Dermatol. 2013 Dec; 22(12):797-9.
Patel F, Marusina AI, Duong C, Adamopoulos IE, Maverakis E. PMID: 24279916; PMCID: PMC4939276.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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The implication of vitamin D and autoimmunity: a comprehensive review. Clin Rev Allergy Immunol. 2013 Oct; 45(2):217-26.
Yang CY, Leung PS, Adamopoulos IE, Gershwin ME. PMID: 23359064; PMCID: PMC6047889.
View in:
PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial clefting. PLoS One. 2013; 8(7):e69333.
Ross AP, Mansilla MA, Choe Y, Helminski S, Sturm R, Maute RL, May SR, Hozyasz KK, Wójcicki P, Mostowska A, Davidson B, Adamopoulos IE, Pleasure SJ, Murray JC, Zarbalis KS. PMID: 23935987; PMCID: PMC3723895.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction. Cytokine Growth Factor Rev. 2013 Apr; 24(2):115-21.
Adamopoulos IE, Pflanz S. PMID: 23165310; PMCID: PMC3605270.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Rheumatoid and pyrophosphate arthritis synovial fibroblasts induce osteoclastogenesis independently of RANKL, TNF and IL-6. J Autoimmun. 2012 Dec; 39(4):369-76.
Dickerson TJ, Suzuki E, Stanecki C, Shin HS, Qui H, Adamopoulos IE. PMID: 22867712; PMCID: PMC3593104.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. J Immunol. 2011 Jul 15; 187(2):951-9.
Adamopoulos IE, Tessmer M, Chao CC, Adda S, Gorman D, Petro M, Chou CC, Pierce RH, Yao W, Lane NE, Laface D, Bowman EP. PMID: 21670317; PMCID: PMC3896980.
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PubMed Mentions:
81 Fields:
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HumansAnimalsCells
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Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis. Autoimmunity. 2011 May; 44(3):243-52.
Chao CC, Chen SJ, Adamopoulos IE, Davis N, Hong K, Vu A, Kwan S, Fayadat-Dilman L, Asio A, Bowman EP. PMID: 20925596.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Structural, cellular, and molecular evaluation of bone erosion in experimental models of rheumatoid arthritis: assessment by μCT, histology, and serum biomarkers. Autoimmunity. 2010 Dec; 43(8):642-53.
Chao CC, Chen SJ, Adamopoulos IE, Judo M, Asio A, Ayanoglu G, Bowman EP. PMID: 20380588.
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6 Fields:
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Animals
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Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J Exp Med. 2010 Mar 15; 207(3):579-89.
Joyce-Shaikh B, Bigler ME, Chao CC, Murphy EE, Blumenschein WM, Adamopoulos IE, Heyworth PG, Antonenko S, Bowman EP, McClanahan TK, Phillips JH, Cua DJ. PMID: 20212065; PMCID: PMC2839155.
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45 Fields:
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HumansAnimalsCells
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Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. Arthritis Res Ther. 2010; 12(1):R29.
Adamopoulos IE, Chao CC, Geissler R, Laface D, Blumenschein W, Iwakura Y, McClanahan T, Bowman EP. PMID: 20167120; PMCID: PMC2875663.
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150 Fields:
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HumansAnimalsCells
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Immune regulation of bone loss by Th17 cells. Arthritis Res Ther. 2008; 10(5):225.
Adamopoulos IE, Bowman EP. PMID: 18983698; PMCID: PMC2592787.
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40 Fields:
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HumansAnimalsCells
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Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. Rheumatology (Oxford). 2008 Dec; 47(12):1761-7.
Harney SM, Vilariño-Güell C, Adamopoulos IE, Sims AM, Lawrence RW, Cardon LR, Newton JL, Meisel C, Pointon JJ, Darke C, Athanasou N, Wordsworth BP, Brown MA. PMID: 18835879.
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PubMed Mentions:
21 Fields:
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Humans
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Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma. Br J Cancer. 2007 Jun 04; 96(11):1716-22.
Lau YS, Adamopoulos IE, Sabokbar A, Giele H, Gibbons CL, Athanasou NA. PMID: 17533390; PMCID: PMC2359921.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Macrophage-mediated biodegradation of poly(DL-lactide-co-glycolide) in vitro. J Biomed Mater Res A. 2006 Dec 01; 79(3):582-90.
Xia Z, Huang Y, Adamopoulos IE, Walpole A, Triffitt JT, Cui Z. PMID: 16817218.
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PubMed Mentions:
6 Fields:
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AnimalsCells
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Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesis. Biochem Biophys Res Commun. 2006 Nov 17; 350(2):478-83.
Adamopoulos IE, Xia Z, Lau YS, Athanasou NA. PMID: 17022947.
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PubMed Mentions:
19 Fields:
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HumansCells
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Osteoclast differentiation and bone resorption in multicentric reticulohistiocytosis. Hum Pathol. 2006 Sep; 37(9):1176-85.
Adamopoulos IE, Wordsworth PB, Edwards JR, Ferguson DJ, Athanasou NA. PMID: 16938523.
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PubMed Mentions:
11 Fields:
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HumansCells
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In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line. Biomaterials. 2006 Sep; 27(26):4557-65.
Xia Z, Grover LM, Huang Y, Adamopoulos IE, Gbureck U, Triffitt JT, Shelton RM, Barralet JE. PMID: 16720039.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCellsPHPublic Health
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LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum. 2006 May; 54(5):1451-62.
Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A. PMID: 16649193.
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PubMed Mentions:
35 Fields:
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HumansAnimalsCells
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Stimulation of osteoclast formation by inflammatory synovial fluid. Virchows Arch. 2006 Jul; 449(1):69-77.
Adamopoulos IE, Danks L, Itonaga I, Locklin RM, Sabokbar A, Ferguson DJ, Athanasou NA. PMID: 16642388.
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PubMed Mentions:
9 Fields:
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HumansCells
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Hepatocyte Growth Factor in Normal and Diseased Bone and Joint Tissues. Current Rheumatology Reviews. 2006 Feb 1; 2(1):1-7.
Adamopoulos AI, Athanasou AN. .
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Synovial fluid macrophages are capable of osteoclast formation and resorption. J Pathol. 2006 Jan; 208(1):35-43.
Adamopoulos IE, Sabokbar A, Wordsworth BP, Carr A, Ferguson DJ, Athanasou NA. PMID: 16278818.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Hepatocyte growth factor in normal and diseased bone and joint tissues. Curr Rheumatol Rev. 2006; 2(1):1-7.
Adamopoulos IE, Athanasou NA. PMID: 25312908.
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PubMed Mentions:
4 Fields: