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Jan Nolta

Title(s)Professor, Hematology and Oncology
SchoolUniversity of California, Davis
Phone916-703-9300
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yazdanyar A, Zhang P, Dolf C, Smit-McBride Z, Cary W, Nolta JA, Zawadzki RJ, Marsh-Armstrong N, Park SS. Effects of intravitreal injection of human CD34+ bone marrow stem cells in a murine model of diabetic retinopathy. Exp Eye Res. 2019 Nov 01; 190:107865. PMID: 31682846.
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    2. Marusina AI, Merleev AA, Luna JI, Olney L, Haigh NE, Yoon D, Guo C, Ovadia EM, Shimoda M, Luxardi G, Boddu S, Lal NN, Takada Y, Lam KS, Liu R, Isseroff RR, Le S, Nolta JA, Kloxin AM, Maverakis E. Tunable hydrogels for mesenchymal stem cell delivery: integrin-induced transcriptome alterations and hydrogel optimization for human wound healing. Stem Cells. 2019 Oct 24. PMID: 31648388.
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    3. Elahi FM, Farwell DG, Nolta JA, Anderson JD. Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. Stem Cells. 2019 Aug 05. PMID: 31381842.
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    4. Nolta JA. Follow the Tennis Ball Like a Golden Retriever. Stem Cells Dev. 2019 Jun 01; 28(11):708. PMID: 31090493.
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    5. Showalter MR, Wancewicz B, Fiehn O, Archard JA, Clayton S, Wagner J, Deng P, Halmai J, Fink KD, Bauer G, Fury B, Perotti NH, Apperson M, Butters J, Belafsky P, Farwell G, Kuhn M, Nolta JA, Anderson JD. Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation. Biochem Biophys Res Commun. 2019 May 14; 512(4):729-735. PMID: 30926165.
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    6. Yuan O, Lin C, Wagner J, Archard JA, Deng P, Halmai J, Bauer G, Fink KD, Fury B, Perotti NH, Walker JE, Pollock K, Apperson M, Butters J, Belafsky P, Farwell DG, Kuhn M, Nolta J, Anderson JD. Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion. Stem Cells Dev. 2019 Mar 15; 28(6):398-409. PMID: 30638129.
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    7. Gao K, Kumar P, Cortez-Toledo E, Hao D, Reynaga L, Rose M, Wang C, Farmer D, Nolta J, Zhou J, Zhou P, Wang A. Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells. Stem Cell Res Ther. 2019 01 22; 10(1):34. PMID: 30670078.
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    8. Nolta JA. Now More Than Ever: The Importance of Reporting Evidence-Based Science. Stem Cells. 2019 01; 37(1):4-5. PMID: 30536672.
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    9. Cortez-Toledo E, Rose M, Agu E, Dahlenburg H, Yao W, Nolta JA, Zhou P. Enhancing Retention of Human Bone Marrow Mesenchymal Stem Cells with Prosurvival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia. Stem Cells Dev. 2019 Jan 15; 28(2):114-119. PMID: 30398391.
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    10. Fierro FA, Magner N, Beegle J, Dahlenburg H, Logan White J, Zhou P, Pepper K, Fury B, Coleal-Bergum DP, Bauer G, Gruenloh W, Annett G, Pifer C, Nolta JA. Mesenchymal stem/stromal cells genetically engineered to produce vascular endothelial growth factor for revascularization in wound healing and ischemic conditions. Transfusion. 2019 02; 59(S1):893-897. PMID: 30383901.
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    11. Shieh AK, Singh SG, Nathe C, Lian E, Haudenschild DR, Nolta JA, Lee CA, Giza E, Kreulen CD. Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus. Cartilage. 2018 Aug 29; 1947603518796125. PMID: 30156865.
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    12. Pham MT, Pollock KM, Rose MD, Cary WA, Stewart HR, Zhou P, Nolta JA, Waldau B. Generation of human vascularized brain organoids. Neuroreport. 2018 05 02; 29(7):588-593. PMID: 29570159.
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    13. Nolta JA. Research Leads to Approved Therapies in the New Era of Living Medicine. Stem Cells. 2018 01; 36(1):1-3. PMID: 29210150.
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    14. Feng JF, Liu J, Zhang L, Jiang JY, Russell M, Lyeth BG, Nolta JA, Zhao M. Electrical Guidance of Human Stem Cells in the Rat Brain. Stem Cell Reports. 2017 07 11; 9(1):177-189. PMID: 28669601.
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    15. Moisseiev E, Anderson JD, Oltjen S, Goswami M, Zawadzki RJ, Nolta JA, Park SS. Protective Effect of Intravitreal Administration of Exosomes Derived from Mesenchymal Stem Cells on Retinal Ischemia. Curr Eye Res. 2017 10; 42(10):1358-1367. PMID: 28636406.
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    16. Duong C, Yoshida S, Chen C, Barisone G, Diaz E, Li Y, Beckett L, Chung J, Antony R, Nolta J, Nitin N, Satake N. Novel targeted therapy for neuroblastoma: silencing the MXD3 gene using siRNA. Pediatr Res. 2017 Sep; 82(3):527-535. PMID: 28419087.
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    17. Kuhn MA, Black AB, Siddiqui MT, Nolta JA, Belafsky PC. Novel murine xenograft model for the evaluation of stem cell therapy for profound dysphagia. Laryngoscope. 2017 10; 127(10):E359-E363. PMID: 28543406.
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    18. Fierro FA, Nolta JA, Adamopoulos IE. Concise Review: Stem Cells in Osteoimmunology. Stem Cells. 2017 06; 35(6):1461-1467. PMID: 28390147.
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    19. Harding A, Cortez-Toledo E, Magner NL, Beegle JR, Coleal-Bergum DP, Hao D, Wang A, Nolta JA, Zhou P. Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways. Stem Cells. 2017 04; 35(4):909-919. PMID: 28248004.
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    20. Nolta JA. Cutting Edge Advances in Stem Cell Biology and Therapy. Stem Cells. 2017 01; 35(1):1-2. PMID: 27873381.
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    21. Park SS, Moisseiev E, Bauer G, Anderson JD, Grant MB, Zam A, Zawadzki RJ, Werner JS, Nolta JA. Advances in bone marrow stem cell therapy for retinal dysfunction. Prog Retin Eye Res. 2017 01; 56:148-165. PMID: 27784628.
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    22. Beegle JR, Magner NL, Kalomoiris S, Harding A, Zhou P, Nacey C, White JL, Pepper K, Gruenloh W, Annett G, Nolta JA, Fierro FA. Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia. Mol Ther Methods Clin Dev. 2016; 3:16053. PMID: 27610394.
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    23. Moisseiev E, Smit-McBride Z, Oltjen S, Zhang P, Zawadzki RJ, Motta M, Murphy CJ, Cary W, Annett G, Nolta JA, Park SS. Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4125-35. PMID: 27537262.
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    24. Deng P, Anderson JD, Yu AS, Annett G, Fink KD, Nolta JA. Engineered BDNF producing cells as a potential treatment for neurologic disease. Expert Opin Biol Ther. 2016 08; 16(8):1025-33. PMID: 27159050.
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    25. Deng P, Torrest A, Pollock K, Dahlenburg H, Annett G, Nolta JA, Fink KD. Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells. Neural Regen Res. 2016 May; 11(5):702-5. PMID: 27335539.
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    26. Nolta JA. "Next-generation" mesenchymal stem or stromal cells for the in vivo delivery of bioactive factors: progressing toward the clinic. Transfusion. 2016 Apr; 56(4):15S-7S. PMID: 27079315.
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    27. Kalomoiris S, Cicchetto AC, Lakatos K, Nolta JA, Fierro FA. Fibroblast Growth Factor 2 Regulates High Mobility Group A2 Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells. J Cell Biochem. 2016 09; 117(9):2128-37. PMID: 26888666.
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    28. Anderson JD, Johansson HJ, Graham CS, Vesterlund M, Pham MT, Bramlett CS, Montgomery EN, Mellema MS, Bardini RL, Contreras Z, Hoon M, Bauer G, Fink KD, Fury B, Hendrix KJ, Chedin F, El-Andaloussi S, Hwang B, Mulligan MS, Lehtiö J, Nolta JA. Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling. Stem Cells. 2016 Mar; 34(3):601-13. PMID: 26782178.
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    29. Fink KD, Deng P, Gutierrez J, Anderson JS, Torrest A, Komarla A, Kalomoiris S, Cary W, Anderson JD, Gruenloh W, Duffy A, Tempkin T, Annett G, Wheelock V, Segal DJ, Nolta JA. Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts. Cell Transplant. 2016; 25(4):677-86. PMID: 26850319.
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    30. Lakatos K, Kalomoiris S, Merkely B, Nolta JA, Fierro FA. Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols. J Cell Biochem. 2016 Feb; 117(2):300-7. PMID: 26212931.
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    31. Pollock K, Dahlenburg H, Nelson H, Fink KD, Cary W, Hendrix K, Annett G, Torrest A, Deng P, Gutierrez J, Nacey C, Pepper K, Kalomoiris S, D Anderson J, McGee J, Gruenloh W, Fury B, Bauer G, Duffy A, Tempkin T, Wheelock V, Nolta JA. Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models. Mol Ther. 2016 05; 24(5):965-77. PMID: 26765769.
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    32. Jung Y, Nolta JA. BMI1 Regulation of Self-Renewal and Multipotency in Human Mesenchymal Stem Cells. Curr Stem Cell Res Ther. 2016; 11(2):131-40. PMID: 26763885.
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    33. Black AB, Dahlenburg H, Pepper K, Nacey C, Pontow S, Kuhn MA, Belafsky PC, Nolta JA. Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy. Hum Gene Ther Methods. 2015 Dec; 26(6):193-6. PMID: 26544924.
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    34. Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson DL. Companion animals: Translational scientist's new best friends. Sci Transl Med. 2015 Oct 07; 7(308):308ps21. PMID: 26446953.
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    35. McMahill BG, Spriet M, Sisó S, Manzer MD, Mitchell G, McGee J, Garcia TC, Borjesson DL, Sieber-Blum M, Nolta JA, Sturges BK. Feasibility Study of Canine Epidermal Neural Crest Stem Cell Transplantation in the Spinal Cords of Dogs. Stem Cells Transl Med. 2015 Oct; 4(10):1173-86. PMID: 26273065.
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    36. Vapniarsky N, Arzi B, Hu JC, Nolta JA, Athanasiou KA. Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine. Stem Cells Transl Med. 2015 Oct; 4(10):1187-98. PMID: 26253713.
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    37. Sheu J, Beltzer J, Fury B, Wilczek K, Tobin S, Falconer D, Nolta J, Bauer G. Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor. Mol Ther Methods Clin Dev. 2015; 2:15020. PMID: 26151065.
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    38. Cary WA, Hori CN, Pham MT, Nacey CA, McGee JL, Hamou M, Berman RF, Bauer G, Nolta JA, Waldau B. Efficient Generation of Induced Pluripotent Stem and Neural Progenitor Cells From Acutely Harvested Dura Mater Obtained During Ventriculoperitoneal Shunt Surgery. World Neurosurg. 2015 Nov; 84(5):1256-66.e1. PMID: 26074438.
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    39. Beegle J, Lakatos K, Kalomoiris S, Stewart H, Isseroff RR, Nolta JA, Fierro FA. Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo. Stem Cells. 2015 Jun; 33(6):1818-28. PMID: 25702874.
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    40. Osborn SL, So M, Hambro S, Nolta JA, Kurzrock EA. Inosculation of blood vessels allows early perfusion and vitality of bladder grafts--implications for bioengineered bladder wall. Tissue Eng Part A. 2015 Jun; 21(11-12):1906-15. PMID: 25794892.
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    41. Barclay SL, Yang Y, Zhang S, Fong R, Barraza A, Nolta JA, Torbett BE, Abedi M, Bauer G, Anderson JS. Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells. Stem Cells. 2015 Mar; 33(3):870-9. PMID: 25524029.
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    42. McMahill BG, Borjesson DL, Sieber-Blum M, Nolta JA, Sturges BK. Stem cells in canine spinal cord injury--promise for regenerative therapy in a large animal model of human disease. Stem Cell Rev Rep. 2015 Feb; 11(1):180-93. PMID: 25173879.
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    43. Nolta JA. New advances in understanding stem cell fate and function. Stem Cells. 2015 Feb; 33(2):313-5. PMID: 25446041.
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    44. Fink KD, Deng P, Torrest A, Stewart H, Pollock K, Gruenloh W, Annett G, Tempkin T, Wheelock V, Nolta JA. Developing stem cell therapies for juvenile and adult-onset Huntington's disease. Regen Med. 2015; 10(5):623-46. PMID: 26237705.
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    45. Chang AI, Schwertschkow AH, Nolta JA, Wu J. Involvement of mesenchymal stem cells in cancer progression and metastases. Curr Cancer Drug Targets. 2015; 15(2):88-98. PMID: 25619387.
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    46. Barisone GA, Satake N, Lewis C, Duong C, Chen C, Lam KS, Nolta J, D?az E. Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells. Blood Cells Mol Dis. 2015 Apr; 54(4):329-35. PMID: 25554682.
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    47. Park SS, Bauer G, Abedi M, Pontow S, Panorgias A, Jonnal R, Zawadzki RJ, Werner JS, Nolta J. Intravitreal autologous bone marrow CD34+ cell therapy for ischemic and degenerative retinal disorders: preliminary phase 1 clinical trial findings. Invest Ophthalmol Vis Sci. 2014 Dec 09; 56(1):81-9. PMID: 25491299.
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    48. Gao W, Zhou P, Ma X, Tschudy-Seney B, Chen J, Magner NL, Revzin A, Nolta JA, Zern MA, Duan Y. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro. PLoS One. 2014; 9(11):e112698. PMID: 25393427.
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    49. Satake N, Duong C, Chen C, Barisone GA, Diaz E, Tuscano J, Rocke DM, Nolta J, Nitin N. Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia. Br J Haematol. 2014 Nov; 167(4):487-99. PMID: 25196579.
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    50. Perez-Cunningham J, Ames E, Smith RC, Peter AK, Naidu R, Nolta JA, Murphy WJ. Natural killer cell subsets differentially reject embryonic stem cells based on licensing. Transplantation. 2014 May 27; 97(10):992-8. PMID: 24704665.
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    51. Clark EA, Kalomoiris S, Nolta JA, Fierro FA. Concise review: MicroRNA function in multipotent mesenchymal stromal cells. Stem Cells. 2014 May; 32(5):1074-82. PMID: 24860868.
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    52. Dasu MR, Ramirez SR, La TD, Gorouhi F, Nguyen C, Lin BR, Mashburn C, Stewart H, Peavy TR, Nolta JA, Isseroff RR. Crosstalk between adrenergic and toll-like receptors in human mesenchymal stem cells and keratinocytes: a recipe for impaired wound healing. Stem Cells Transl Med. 2014 Jun; 3(6):745-59. PMID: 24760207.
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    53. Osborn SL, Thangappan R, Luria A, Lee JH, Nolta J, Kurzrock EA. Induction of human embryonic and induced pluripotent stem cells into urothelium. Stem Cells Transl Med. 2014 May; 3(5):610-9. PMID: 24657961.
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    54. Gericota B, Anderson JS, Mitchell G, Borjesson DL, Sturges BK, Nolta JA, Sieber-Blum M. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury. Stem Cells Transl Med. 2014 Mar; 3(3):334-45. PMID: 24443004.
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    55. Nolta JA. Editorial: 2013 - a year of clinical success and great scientific innovation in the stem cell field. Stem Cells. 2014 Jan; 32(1):1-2. PMID: 24375745.
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    56. Binder BY, Sondergaard CS, Nolta JA, Leach JK. Lysophosphatidic acid enhances stromal cell-directed angiogenesis. PLoS One. 2013; 8(12):e82134. PMID: 24312635.
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    57. Lee JK, Responte DJ, Cissell DD, Hu JC, Nolta JA, Athanasiou KA. Clinical translation of stem cells: insight for cartilage therapies. Crit Rev Biotechnol. 2014 Mar; 34(1):89-100. PMID: 24083452.
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    58. Plowman EK, Bijangi-Vishehsaraei K, Halum S, Cates D, Hanenberg H, Domer AS, Nolta JA, Belafsky PC. Autologous myoblasts attenuate atrophy and improve tongue force in a denervated tongue model: a pilot study. Laryngoscope. 2014 Feb; 124(2):E20-6. PMID: 23929623.
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    59. Magner NL, Jung Y, Wu J, Nolta JA, Zern MA, Zhou P. Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway. Stem Cells. 2013 Oct; 31(10):2095-103. PMID: 23836547.
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    60. Yik JH, Li H, Acharya C, Kumari R, Fierro F, Haudenschild DR, Nolta J, Di Cesare PE. The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation. Cartilage. 2013 Oct; 4(4):329-38. PMID: 26069677.
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    61. Yao W, Guan M, Jia J, Dai W, Lay YA, Amugongo S, Liu R, Olivos D, Saunders M, Lam KS, Nolta J, Olvera D, Ritchie RO, Lane NE. Reversing bone loss by directing mesenchymal stem cells to bone. Stem Cells. 2013 Sep; 31(9):2003-14. PMID: 23818248.
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    62. Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA. Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Transl Med. 2013 Jun; 2(6):409-19. PMID: 23681950.
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    63. Kalomoiris S, Lawson J, Chen RX, Bauer G, Nolta JA, Anderson JS. CD25 preselective anti-HIV vectors for improved HIV gene therapy. Hum Gene Ther Methods. 2012 Dec; 23(6):366-75. PMID: 23216020.
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    64. Annett G, Bauer G, Nolta JA. Mesenchymal stem cells for trinucleotide repeat disorders. Methods Mol Biol. 2013; 1010:79-91. PMID: 23754220.
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    65. Liu J, Githinji J, Mclaughlin B, Wilczek K, Nolta J. Role of miRNAs in neuronal differentiation from human embryonic stem cell-derived neural stem cells. Stem Cell Rev Rep. 2012 Dec; 8(4):1129-37. PMID: 23054963.
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    66. Kumari R, Li H, Haudenschild DR, Fierro F, Carlson CS, Overn P, Gupta L, Gupta K, Nolta J, Yik JH, Di Cesare PE. The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Carcinogenesis. 2012 Nov; 33(11):2076-83. PMID: 22847180.
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    67. Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. Signaling defects in iPSC-derived fragile X premutation neurons. Hum Mol Genet. 2012 Sep 01; 21(17):3795-805. PMID: 22641815.
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    68. Murphy WJ, Nolta JA. Autoimmune T cells lured to a FASL web of death by MSCs. Cell Stem Cell. 2012 May 04; 10(5):485-7. PMID: 22560070.
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    69. Walker JE, Chen RX, McGee J, Nacey C, Pollard RB, Abedi M, Bauer G, Nolta JA, Anderson JS. Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector. J Virol. 2012 May; 86(10):5719-29. PMID: 22398281.
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    70. Park SS, Caballero S, Bauer G, Shibata B, Roth A, Fitzgerald PG, Forward KI, Zhou P, McGee J, Telander DG, Grant MB, Nolta JA. Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2012 Feb; 53(2):986-94. PMID: 22247454.
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    71. Mathews G, Sondergaard C, Jeffreys A, Childs W, Le BL, Sahota A, Najibi S, Nolta J, Si MS. Computational analysis of contractility in engineered heart tissue. IEEE Trans Biomed Eng. 2012 May; 59(5):1429-35. PMID: 22361653.
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    72. Guan M, Yao W, Liu R, Lam KS, Nolta J, Jia J, Panganiban B, Meng L, Zhou P, Shahnazari M, Ritchie RO, Lane NE. Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. Nat Med. 2012 Feb 05; 18(3):456-62. PMID: 22306732.
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    73. Feng JF, Liu J, Zhang XZ, Zhang L, Jiang JY, Nolta J, Zhao M. Guided migration of neural stem cells derived from human embryonic stem cells by an electric field. Stem Cells. 2012 Feb; 30(2):349-55. PMID: 22076946.
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    74. Armstrong L, Lako M, Buckley N, Lappin TR, Murphy MJ, Nolta JA, Pittenger M, Stojkovic M. Editorial: Our top 10 developments in stem cell biology over the last 30 years. Stem Cells. 2012 Jan; 30(1):2-9. PMID: 22162299.
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    75. Jung Y, Bauer G, Nolta JA. Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: progress toward safe clinical products. Stem Cells. 2012 Jan; 30(1):42-7. PMID: 21898694.
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    76. Yarborough M, Tempkin T, Nolta J, Joyce N. The Complex Ethics of First In Human Stem Cell Clinical Trials. AJOB Neurosci. 2012; 3(2). PMID: 24273680.
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    77. Olson SD, Pollock K, Kambal A, Cary W, Mitchell GM, Tempkin J, Stewart H, McGee J, Bauer G, Kim HS, Tempkin T, Wheelock V, Annett G, Dunbar G, Nolta JA. Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. Mol Neurobiol. 2012 Feb; 45(1):87-98. PMID: 22161544.
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    78. Olson SD, Kambal A, Pollock K, Mitchell GM, Stewart H, Kalomoiris S, Cary W, Nacey C, Pepper K, Nolta JA. Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin. Mol Cell Neurosci. 2012 Mar; 49(3):271-81. PMID: 22198539.
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    79. Fierro FA, Kalomoiris S, Sondergaard CS, Nolta JA. Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy. Stem Cells. 2011 Nov; 29(11):1727-37. PMID: 21898687.
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    80. Zhou P, Lessa N, Estrada DC, Severson EB, Lingala S, Zern MA, Nolta JA, Wu J. Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice. Liver Transpl. 2011 Apr; 17(4):418-27. PMID: 21445925.
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    81. Gruenloh W, Kambal A, Sondergaard C, McGee J, Nacey C, Kalomoiris S, Pepper K, Olson S, Fierro F, Nolta JA. Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells. Tissue Eng Part A. 2011 Jun; 17(11-12):1517-25. PMID: 21275830.
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    82. Chen X, Lingala S, Khoobyari S, Nolta J, Zern MA, Wu J. Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. J Hepatol. 2011 Oct; 55(4):838-45. PMID: 21334406.
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    83. Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol Ther. 2011 Mar; 19(3):584-93. PMID: 21119622.
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    84. Joyce N, Annett G, Wirthlin L, Olson S, Bauer G, Nolta JA. Mesenchymal stem cells for the treatment of neurodegenerative disease. Regen Med. 2010 Nov; 5(6):933-46. PMID: 21082892.
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    85. Meyerrose T, Olson S, Pontow S, Kalomoiris S, Jung Y, Annett G, Bauer G, Nolta JA. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev. 2010 Sep 30; 62(12):1167-74. PMID: 20920540.
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    86. Sondergaard CS, Hodonsky CJ, Khait L, Shaw J, Sarkar B, Birla R, Bove E, Nolta J, Si MS. Human thymus mesenchymal stromal cells augment force production in self-organized cardiac tissue. Ann Thorac Surg. 2010 Sep; 90(3):796-803; discussion 803-4. PMID: 20732499.
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    87. Stojkovic M, Pittenger MF, Nolta JA, Lako M, Lappin TR, Murphy MJ. Stem Cells' position statement on hESC research. Stem Cells. 2010 Sep; 28(9):1A. PMID: 20809560.
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    88. Zhou P, Gross S, Liu JH, Yu BY, Feng LL, Nolta J, Sharma V, Piwnica-Worms D, Qiu SX. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. FASEB J. 2010 Dec; 24(12):4722-32. PMID: 20696856.
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    89. Rosová I, Link D, Nolta JA. shRNA-mediated decreases in c-Met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair. Tissue Eng Part A. 2010 Aug; 16(8):2627-39. PMID: 20367286.
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    91. Anderson JS, Walker J, Nolta JA, Bauer G. Specific transduction of HIV-susceptible cells for CCR5 knockdown and resistance to HIV infection: a novel method for targeted gene therapy and intracellular immunization. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):152-61. PMID: 19593160.
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    95. Capoccia BJ, Robson DL, Levac KD, Maxwell DJ, Hohm SA, Neelamkavil MJ, Bell GI, Xenocostas A, Link DC, Piwnica-Worms D, Nolta JA, Hess DA. Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood. 2009 May 21; 113(21):5340-51. PMID: 19324906.
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    96. Rosová I, Dao M, Capoccia B, Link D, Nolta JA. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells. 2008 Aug; 26(8):2173-82. PMID: 18511601.
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    97. Rich JT, Rosová I, Nolta JA, Myckatyn TM, Sandell LJ, McAlinden A. Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells. Biochem Biophys Res Commun. 2008 Jul 18; 372(1):230-5. PMID: 18482578.
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    99. Meyerrose TE, Roberts M, Ohlemiller KK, Vogler CA, Wirthlin L, Nolta JA, Sands MS. Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease. Stem Cells. 2008 Jul; 26(7):1713-22. PMID: 18436861.
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    103. Hess DA, Craft TP, Wirthlin L, Hohm S, Zhou P, Eades WC, Creer MH, Sands MS, Nolta JA. Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity. Stem Cells. 2008 Mar; 26(3):611-20. PMID: 18055447.
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    104. Maxwell DJ, Bonde J, Hess DA, Hohm SA, Lahey R, Zhou P, Creer MH, Piwnica-Worms D, Nolta JA. Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells. Stem Cells. 2008 Feb; 26(2):517-24. PMID: 18055451.
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    105. Nervi B, Rettig MP, Ritchey JK, Wang HL, Bauer G, Walker J, Bonyhadi ML, Berenson RJ, Prior JL, Piwnica-Worms D, Nolta JA, DiPersio JF. Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice. Exp Hematol. 2007 Dec; 35(12):1823-38. PMID: 17764813.
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    106. Qiu SX, Dan C, Ding LS, Peng S, Chen SN, Farnsworth NR, Nolta J, Gross ML, Zhou P. A triterpene glycoside from black cohosh that inhibits osteoclastogenesis by modulating RANKL and TNFalpha signaling pathways. Chem Biol. 2007 Jul; 14(7):860-9. PMID: 17656322.
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    107. Hess DA, Bonde J, Craft TP, Craft TC, Wirthlin L, Hohm S, Lahey R, Todt LM, Dipersio JF, Devine SM, Nolta JA. Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor. Biol Blood Marrow Transplant. 2007 Apr; 13(4):398-411. PMID: 17382247.
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    108. Dao MA, Creer MH, Nolta JA, Verfaillie CM. Biology of umbilical cord blood progenitors in bone marrow niches. Blood. 2007 Jul 01; 110(1):74-81. PMID: 17371947.
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    109. Partlow KC, Chen J, Brant JA, Neubauer AM, Meyerrose TE, Creer MH, Nolta JA, Caruthers SD, Lanza GM, Wickline SA. 19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons. FASEB J. 2007 Jun; 21(8):1647-54. PMID: 17284484.
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    112. Hess DA, Wirthlin L, Craft TP, Herrbrich PE, Hohm SA, Lahey R, Eades WC, Creer MH, Nolta JA. Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood. 2006 Mar 01; 107(5):2162-9. PMID: 16269619.
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    115. Bonde J, Hess DA, Nolta JA. Recent advances in hematopoietic stem cell biology. Curr Opin Hematol. 2004 Nov; 11(6):392-8. PMID: 15548993.
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    117. Hess DA, Meyerrose TE, Wirthlin L, Craft TP, Herrbrich PE, Creer MH, Nolta JA. Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood. 2004 Sep 15; 104(6):1648-55. PMID: 15178579.
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    119. Kohn DB, Sadelain M, Dunbar C, Bodine D, Kiem HP, Candotti F, Tisdale J, Riviére I, Blau CA, Richard RE, Sorrentino B, Nolta J, Malech H, Brenner M, Cornetta K, Cavagnaro J, High K, Glorioso J. American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. Mol Ther. 2003 Aug; 8(2):180-7. PMID: 12907140.
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    121. Wu GD, Nolta JA, Jin YS, Barr ML, Yu H, Starnes VA, Cramer DV. Migration of mesenchymal stem cells to heart allografts during chronic rejection. Transplantation. 2003 Mar 15; 75(5):679-85. PMID: 12640309.
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    122. Wang X, Ge S, McNamara G, Hao QL, Crooks GM, Nolta JA. Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. Blood. 2003 May 15; 101(10):4201-8. PMID: 12560238.
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    123. Gussoni E, Bennett RR, Muskiewicz KR, Meyerrose T, Nolta JA, Gilgoff I, Stein J, Chan YM, Lidov HG, Bönnemann CG, Von Moers A, Morris GE, Den Dunnen JT, Chamberlain JS, Kunkel LM, Weinberg K. Long-term persistence of donor nuclei in a Duchenne muscular dystrophy patient receiving bone marrow transplantation. J Clin Invest. 2002 Sep; 110(6):807-14. PMID: 12235112.
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    125. Nolta JA, Thiemann FT, Arakawa-Hoyt J, Dao MA, Barsky LW, Moore KA, Lemischka IR, Crooks GM. The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors. Leukemia. 2002 Mar; 16(3):352-61. PMID: 11896538.
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    128. Nolta JA, Jordan CT. Spotlight on hematopoietic stem cells: looking beyond dogma. Introduction. Leukemia. 2001 Nov; 15(11):1677-80. PMID: 11681405.
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    129. Wang X, Dao MA, Kuo I, Nolta JA. Phenotypic comparison of extrathymic human bone-marrow-derived T cells with thymic-selected T cells recovered from different tissues. Clin Immunol. 2001 Sep; 100(3):339-48. PMID: 11513547.
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    130. Tsark EC, Dao MA, Wang X, Weinberg K, Nolta JA. IL-7 enhances the responsiveness of human T cells that develop in the bone marrow of athymic mice. J Immunol. 2001 Jan 01; 166(1):170-81. PMID: 11123290.
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    131. Evans ME, Jordan CT, Chang SM, Conrad C, Gerberding JL, Kaufman HL, Mayhall CG, Nolta JA, Pilaro AM, Sullivan S, Weber DJ, Wivel NA. Clinical infection control in gene therapy: a multidisciplinary conference. Infect Control Hosp Epidemiol. 2000 Oct; 21(10):659-73. PMID: 11083185.
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    132. Dao MA, Nolta JA. CD34: to select or not to select? That is the question. Leukemia. 2000 May; 14(5):773-6. PMID: 10803504.
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    133. Parkman R, Weinberg K, Crooks G, Nolta J, Kapoor N, Kohn D. Gene therapy for adenosine deaminase deficiency. Annu Rev Med. 2000; 51:33-47. PMID: 10774451.
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    134. Arakawa-Hoyt J, Dao MA, Thiemann F, Hao QL, Ertl DC, Weinberg KI, Crooks GM, Nolta JA. The number and generative capacity of human B lymphocyte progenitors, measured in vitro and in vivo, is higher in umbilical cord blood than in adult or pediatric bone marrow. Bone Marrow Transplant. 1999 Dec; 24(11):1167-76. PMID: 10642804.
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    137. Dao MA, Tsark E, Nolta JA. Animal xenograft models for evaluation of gene transfer into human hematopoietic stem cells. Curr Opin Mol Ther. 1999 Oct; 1(5):553-7. PMID: 11249661.
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    138. Erdreich-Epstein A, Liu M, Kant AM, Izadi KD, Nolta JA, Durden DL. Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages. J Leukoc Biol. 1999 Apr; 65(4):523-34. PMID: 10204582.
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    139. Dao MA, Hashino K, Kato I, Nolta JA. Adhesion to fibronectin maintains regenerative capacity during ex vivo culture and transduction of human hematopoietic stem and progenitor cells. Blood. 1998 Dec 15; 92(12):4612-21. PMID: 9845527.
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    140. Dunbar CE, Kohn DB, Schiffmann R, Barton NW, Nolta JA, Esplin JA, Pensiero M, Long Z, Lockey C, Emmons RV, Csik S, Leitman S, Krebs CB, Carter C, Brady RO, Karlsson S. Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation. Hum Gene Ther. 1998 Nov 20; 9(17):2629-40. PMID: 9853529.
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    142. Kohn DB, Hershfield MS, Carbonaro D, Shigeoka A, Brooks J, Smogorzewska EM, Barsky LW, Chan R, Burotto F, Annett G, Nolta JA, Crooks G, Kapoor N, Elder M, Wara D, Bowen T, Madsen E, Snyder FF, Bastian J, Muul L, Blaese RM, Weinberg K, Parkman R. T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. Nat Med. 1998 Jul; 4(7):775-80. PMID: 9662367.
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    148. Dao MA, Pepper KA, Nolta JA. Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model. Stem Cells. 1997; 15(6):443-54. PMID: 9402657.
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    149. Nolta JA, Dao MA, Wells S, Smogorzewska EM, Kohn DB. Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice. Proc Natl Acad Sci U S A. 1996 Mar 19; 93(6):2414-9. PMID: 8637888.
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    152. Kohn DB, Weinberg KI, Nolta JA, Heiss LN, Lenarsky C, Crooks GM, Hanley ME, Annett G, Brooks JS, el-Khoureiy A. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med. 1995 Oct; 1(10):1017-23. PMID: 7489356.
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    155. Hanley ME, Nolta JA, Parkman R, Kohn DB. Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer. Blood Cells. 1994; 20(2-3):539-43; discussion 544-6. PMID: 7538356.
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    158. Tishler DM, Weinberg KI, Sender LS, Nolta JA, Raffel C. Multidrug resistance gene expression in pediatric primitive neuroectodermal tumors of the central nervous system. J Neurosurg. 1992 Mar; 76(3):507-12. PMID: 1346632.
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    159. Weinthal J, Nolta JA, Yu XJ, Lilley J, Uribe L, Kohn DB. Expression of human glucocerebrosidase following retroviral vector-mediated transduction of murine hematopoietic stem cells. Bone Marrow Transplant. 1991 Nov; 8(5):403-12. PMID: 1768976.
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    161. Lenarsky C, Weinberg K, Petersen J, Nolta J, Brooks J, Annett G, Kohn D, Parkman R. Autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide purged marrows for children with acute non-lymphoblastic leukemia in second remission. Bone Marrow Transplant. 1990 Dec; 6(6):425-9. PMID: 2097012.
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    162. Ozkaynak MF, Nolta J, Parkman R. In vitro purging of human rhabdomyosarcoma cells using 4-hydroperoxycyclophosphamide. Cancer Res. 1990 Mar 01; 50(5):1455-8. PMID: 2302710.
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    163. Nolta JA, Sender LS, Barranger JA, Kohn DB. Expression of human glucocerebrosidase in murine long-term bone marrow cultures after retroviral vector-mediated transfer. Blood. 1990 Feb 01; 75(3):787-97. PMID: 2297579.
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