Deborah Lieu

TitleAsst Prof
InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gluck JM, Herren AW, Yechikov S, Kao HKJ, Khan A, Phinney BS, Chiamvimonvat N, Chan JW, Lieu D. Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix. PLoS One. 2017; 12(9):e0185125. PMID: 28934329.
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    2. Yechikov S, Copaciu R, Gluck JM, Deng W, Chiamvimonvat N, Chan JW, Lieu D. Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. Stem Cells. 2016 11; 34(11):2670-2680. PMID: 27434649.
      View in: PubMed
    3. Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu D, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). PMID: 27162031; PMCID: PMC4869994 [Available on 05/01/17].
    4. Awasthi S, Izu LT, Mao Z, Jian Z, Landas T, Lerner A, Shimkunas R, Woldeyesus R, Bossuyt J, Wood B, Chen YJ, Matthews DL, Lieu D, Chiamvimonvat N, Lam KS, Chen-Izu Y, Chan JW. Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes. Circ Res. 2016 Jan 22; 118(2):e19-28. PMID: 26643875; PMCID: PMC4740258 [Available on 01/22/17].
    5. Collier BB, Awasthi S, Lieu D, Chan JW. Non-linear optical flow cytometry using a scanned, Bessel beam light-sheet. Sci Rep. 2015 May 29; 5:10751. PMID: 26021750; PMCID: PMC4448227.
    6. Zhang XD, Lieu D, Chiamvimonvat N. Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias. Heart Rhythm. 2015 Aug; 12(8):1845-51. PMID: 25956967.
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    7. Poon E, Keung W, Liang Y, Ramalingam R, Yan B, Zhang S, Chopra A, Moore J, Herren A, Lieu D, Wong HS, Weng Z, Wong OT, Lam YW, Tomaselli GF, Chen C, Boheler KR, Li RA. Proteomic Analysis of Human Pluripotent Stem Cell-Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and Maturation. Circ Cardiovasc Genet. 2015 Jun; 8(3):427-36. PMID: 25759434.
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    8. Karakikes I, Senyei GD, Hansen J, Kong CW, Azeloglu EU, Stillitano F, Lieu D, Wang J, Ren L, Hulot JS, Iyengar R, Li RA, Hajjar RJ. Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. Stem Cells Transl Med. 2014 Jan; 3(1):18-31. PMID: 24324277; PMCID: PMC3902291.
    9. Zhang XD, Timofeyev V, Li N, Myers RE, Zhang DM, Singapuri A, Lau VC, Bond CT, Adelman J, Lieu D, Chiamvimonvat N. Critical roles of a small conductance Ca²?-activated K? channel (SK3) in the repolarization process of atrial myocytes. Cardiovasc Res. 2014 Feb 01; 101(2):317-25. PMID: 24282291; PMCID: PMC3896251.
    10. Poon E, Yan B, Zhang S, Rushing S, Keung W, Ren L, Lieu D, Geng L, Kong CW, Wang J, Wong HS, Boheler KR, Li RA. Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for maturation. PLoS One. 2013; 8(10):e77784. PMID: 24204964.
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    11. Wang J, Chen A, Lieu D, Karakikes I, Chen G, Keung W, Chan CW, Hajjar RJ, Costa KD, Khine M, Li RA. Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias. Biomaterials. 2013 Nov; 34(35):8878-86. PMID: 23942210.
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    12. Lieu D, Fu JD, Chiamvimonvat N, Tung KC, McNerney GP, Huser T, Keller G, Kong CW, Li RA. Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Arrhythm Electrophysiol. 2013 Feb; 6(1):191-201. PMID: 23392582; PMCID: PMC3757253.
    13. Lieu D, Turnbull IC, Costa KD, Li RA. Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies. Drug Discov Today Dis Models. 2012; 9(4):e209-e217. PMID: 29422934.
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    14. Fu JD, Rushing SN, Lieu D, Chan CW, Kong CW, Geng L, Wilson KD, Chiamvimonvat N, Boheler KR, Wu JC, Keller G, Hajjar RJ, Li RA. Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. PLoS One. 2011; 6(11):e27417. PMID: 22110643; PMCID: PMC3217986.
    15. Awasthi S, Matthews DL, Li RA, Chiamvimonvat N, Lieu D, Chan JW. Label-free identification and characterization of human pluripotent stem cell-derived cardiomyocytes using second harmonic generation (SHG) microscopy. J Biophotonics. 2012 Jan; 5(1):57-66. PMID: 22083829; PMCID: PMC3817927.
    16. Chen A, Lieu D, Freschauf L, Lew V, Sharma H, Wang J, Nguyen D, Karakikes I, Hajjar RJ, Gopinathan A, Botvinick E, Fowlkes CC, Li RA, Khine M. Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. Adv Mater. 2011 Dec 22; 23(48):5785-91. PMID: 22065428.
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    17. Luna JI, Ciriza J, Garcia-Ojeda ME, Kong M, Herren A, Lieu D, Li RA, Fowlkes CC, Khine M, McCloskey KE. Multiscale biomimetic topography for the alignment of neonatal and embryonic stem cell-derived heart cells. Tissue Eng Part C Methods. 2011 May; 17(5):579-88. PMID: 21235325.
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    18. Rushing SN, Herren AW, Lieu D, Li RA. Manipulations of microRNA in human pluripotent stem cells and their derivatives. Methods Mol Biol. 2011; 690:107-20. PMID: 21042988.
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    19. Lee YK, Ng KM, Lai WH, Man C, Lieu D, Lau CP, Tse HF, Siu CW. Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway. Acta Pharmacol Sin. 2011 Jan; 32(1):52-61. PMID: 21151160; PMCID: PMC4003319.
    20. Jiang P, Rushing SN, Kong CW, Fu J, Lieu D, Chan CW, Deng W, Li RA. Electrophysiological properties of human induced pluripotent stem cells. Am J Physiol Cell Physiol. 2010 Mar; 298(3):C486-95. PMID: 19955484; PMCID: PMC2838581.
    21. Lieu D, Liu J, Siu CW, McNerney GP, Tse HF, Abu-Khalil A, Huser T, Li RA. Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes. Stem Cells Dev. 2009 Dec; 18(10):1493-500. PMID: 19290776; PMCID: PMC3139544.
    22. Chan JW, Lieu D. Label-free biochemical characterization of stem cells using vibrational spectroscopy. J Biophotonics. 2009 Nov; 2(11):656-68. PMID: 19653219.
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    23. Liu J, Lieu D, Siu CW, Fu JD, Tse HF, Li RA. Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression. Am J Physiol Cell Physiol. 2009 Jul; 297(1):C152-9. PMID: 19357236; PMCID: PMC2711646.
    24. Chan JW, Lieu D, Huser T, Li RA. Label-free separation of human embryonic stem cells and their cardiac derivatives using Raman spectroscopy. Anal Chem. 2009 Feb 15; 81(4):1324-31. PMID: 19152312; PMCID: PMC2652839.
    25. Lieu D, Chan YC, Lau CP, Tse HF, Siu CW, Li RA. Overexpression of HCN-encoded pacemaker current silences bioartificial pacemakers. Heart Rhythm. 2008 Sep; 5(9):1310-7. PMID: 18693074.
      View in: PubMed
    26. Kurzrock EA, Lieu D, Degraffenried LA, Chan CW, Isseroff RR. Label-retaining cells of the bladder: candidate urothelial stem cells. Am J Physiol Renal Physiol. 2008 Jun; 294(6):F1415-21. PMID: 18367656.
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    27. Xue T, Siu CW, Lieu D, Lau CP, Tse HF, Li RA. Mechanistic role of I(f) revealed by induction of ventricular automaticity by somatic gene transfer of gating-engineered pacemaker (HCN) channels. Circulation. 2007 Apr 10; 115(14):1839-50. PMID: 17389267; PMCID: PMC2698014.
    28. Lieu D, Degraffenried LA, Isseroff RR, Kurzrock EA. Beta1 integrin expression pattern in transitional urothelium does not allow for efficient stem cell enrichment as in other epithelia. Tissue Eng. 2007 Feb; 13(2):263-70. PMID: 17518562.
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    29. Barakat AI, Lieu D, Gojova A. Secrets of the code: do vascular endothelial cells use ion channels to decipher complex flow signals? Biomaterials. 2006 Feb; 27(5):671-8. PMID: 16112724.
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    30. Kurzrock EA, Lieu D, deGraffenried LA, Isseroff RR. Rat urothelium: improved techniques for serial cultivation, expansion, freezing and reconstitution onto acellular matrix. J Urol. 2005 Jan; 173(1):281-5. PMID: 15592097.
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    31. Lieu D, Pappone PA, Barakat AI. Differential membrane potential and ion current responses to different types of shear stress in vascular endothelial cells. Am J Physiol Cell Physiol. 2004 Jun; 286(6):C1367-75. PMID: 14761889.
      View in: PubMed
    32. Barakat A, Lieu D. Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress. Cell Biochem Biophys. 2003; 38(3):323-43. PMID: 12794271.
      View in: PubMed