Bruce D Hammock

Title(s)Professor, Entomology
SchoolUniversity of California, Davis
Address90 Briggs Hall
CA 95616
Phone530-752-7519
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. Front Pharmacol. 2021; 12:778470. Wagner KM, Yang J, Morisseau C, Hammock BD. PMID: 34975481; PMCID: PMC8719166.
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    2. 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity. Pharmaceuticals (Basel). 2021 Dec 17; 14(12). Martín-López J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vázquez S. PMID: 34959721; PMCID: PMC8703317.
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    3. Author Correction: Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2021 Dec 14; 11(1):24259. Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 34907191; PMCID: PMC8671385.
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    4. Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity. Front Pharmacol. 2021; 12:744776. Jankiewicz WK, Barnett SD, Stavniichuk A, Hwang SH, Hammock BD, Belayet JB, Khan AH, Imig JD. PMID: 34955823; PMCID: PMC8695932.
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    5. New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. Chem Res Toxicol. 2021 Nov 24. Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD. PMID: 34817988.
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    6. Soluble epoxide hydrolase inhibitor can protect the femoral head against tobacco smoke exposure-induced osteonecrosis in spontaneously hypertensive rats. Toxicology. 2021 Nov 18; 465:153045. Xu J, Qiu X, Yu G, Ly M, Yang J, Silva RM, Zhang X, Yu M, Wang Y, Hammock B, Pinkerton KE, Zhao D. PMID: 34801612.
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    7. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021 Nov 11; 51:116507. Wilt S, Kodani S, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 34794001.
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    8. Clinical and preclinical evidence for roles of soluble epoxide hydrolase in osteoarthritis knee pain. Arthritis Rheumatol. 2021 Oct 21. Gowler PRW, Turnbull J, Shahtaheri M, Gohir S, Kelly T, McReynolds C, Jun Y, Jha RR, Fernandes GS, Zhang W, Doherty M, Walsh DA, Hammock BD, Valdes AM, Barrett DA, Chapman V. PMID: 34672113.
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    9. Eicosanoid regulation of debris-stimulated metastasis. Proc Natl Acad Sci U S A. 2021 Oct 12; 118(41). Deng J, Yang H, Haak VM, Yang J, Kipper FC, Barksdale C, Hwang SH, Gartung A, Bielenberg DR, Subbian S, Ho KK, Ye X, Fan D, Sun Y, Hammock BD, Panigrahy D. PMID: 34607951.
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    10. Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction. Cardiovasc Drugs Ther. 2021 Sep 09. Thai PN, Ren L, Xu W, Overton J, Timofeyev V, Nader CE, Haddad M, Yang J, Gomes AV, Hammock BD, Chiamvimonvat N, Sirish P. PMID: 34499283.
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    11. Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development. Molecules. 2021 Aug 19; 26(16). McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. PMID: 34443621.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function. Sci Rep. 2021 08 16; 11(1):16555. Bergmann CB, Hammock BD, Wan D, Gogolla F, Goetzman H, Caldwell CC, Supp DM. PMID: 34400718; PMCID: PMC8368302.
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    13. Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway. Food Chem Toxicol. 2021 Oct; 156:112516. Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC. PMID: 34411643.
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    14. Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice. Int J Mol Sci. 2021 Jul 31; 22(15). Yang Y, Xu X, Wu H, Yang J, Chen J, Morisseau C, Hammock BD, Bettaieb A, Zhao L. PMID: 34361032.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. Br J Pharmacol. 2021 Jul 13. Khan MAH, Hwang SH, Barnett SD, Stavniichuk A, Jankiewicz WK, Hammock BD, Imig JD. PMID: 34255857.
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    16. Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis. Eur J Med Chem. 2021 Nov 05; 223:113678. Du F, Sun W, Morisseau C, Hammock BD, Bao X, Liu Q, Wang C, Zhang T, Yang H, Zhou J, Xiao W, Liu Z, Chen G. PMID: 34218083.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve. J Affect Disord. 2021 09 01; 292:565-573. Wang S, Ishima T, Qu Y, Shan J, Chang L, Wei Y, Zhang J, Pu Y, Fujita Y, Tan Y, Wang X, Ma L, Wan X, Hammock BD, Hashimoto K. PMID: 34147969.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss. Free Radic Biol Med. 2021 08 20; 172:48-57. Koike S, Hsu MF, Bettaieb A, Chu B, Matsumoto N, Morisseau C, Havel PJ, Huising MO, Hammock BD, Haj FG. PMID: 34038767.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. Int J Mol Sci. 2021 May 08; 22(9). Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD. PMID: 34066758.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. J Med Chem. 2021 05 13; 64(9):5429-5446. Codony S, Calvó-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Pérez C, Rodríguez-Franco MI, Pizarro-Delgado J, Corpas R, Griñán-Ferré C, Pallàs M, Sanfeliu C, Vázquez-Carrera M, Hammock BD, Feixas F, Vázquez S. PMID: 33945278.
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    21. A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis. Int J Mol Sci. 2021 Apr 28; 22(9). Jonnalagadda D, Wan D, Chun J, Hammock BD, Kihara Y. PMID: 33925035.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    22. Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections. Front Physiol. 2021; 12:663869. McReynolds CB, Cortes-Puch I, Ravindran R, Khan IH, Hammock BG, Shih PB, Hammock BD, Yang J. PMID: 33868029.
      View in: PubMed   Mentions: 3  
    23. Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. Sci Rep. 2021 03 29; 11(1):7042. Tiwari S, Yang J, Morisseau C, Durbin-Johnson B, Hammock BD, Gomes AV. PMID: 33782432.
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    24. Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain. ACS Omega. 2021 Mar 16; 6(10):7165-7174. Singh N, Barnych B, Wagner KM, Wan D, Morisseau C, Hammock BD. PMID: 33748630.
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    25. Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. Int J Mol Sci. 2021 Feb 08; 22(4). Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM. PMID: 33567578.
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    26. Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative. J Med Chem. 2021 02 25; 64(4):1856-1872. Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. PMID: 33550801.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    27. Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence. J Pain Res. 2021; 14:61-72. Wang Y, Wagner KM, Morisseau C, Hammock BD. PMID: 33488116.
      View in: PubMed   Mentions: 1  
    28. Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. J Med Chem. 2021 01 14; 64(1):184-215. Sun CP, Zhang XY, Morisseau C, Hwang SH, Zhang ZJ, Hammock BD, Ma XC. PMID: 33369424.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy. J Mol Cell Cardiol. 2021 05; 154:80-91. Wang L, Zhao D, Tang L, Li H, Liu Z, Gao J, Edin ML, Zhang H, Zhang K, Chen J, Zhu X, Wang D, Zeldin DC, Hammock BD, Wang J, Huang H. PMID: 33378686.
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    30. N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain. J Nat Prod. 2020 12 24; 83(12):3689-3697. Singh N, Barnych B, Morisseau C, Wagner KM, Wan D, Takeshita A, Pham H, Xu T, Dandekar A, Liu JY, Hammock BD. PMID: 33320645.
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    31. An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. Sci Transl Med. 2020 12 09; 12(573). Ghosh A, Comerota MM, Wan D, Chen F, Propson NE, Hwang SH, Hammock BD, Zheng H. PMID: 33298560.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    32. EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua. Sci Rep. 2020 11 19; 10(1):20183. Vatanparast M, Ahmed S, Lee DH, Hwang SH, Hammock B, Kim Y. PMID: 33214688.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    33. ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizing Enzymes Involved. Nutrients. 2020 Oct 28; 12(11). Tu M, Wang W, Zhang G, Hammock BD. PMID: 33126566.
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    34. Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABAA Receptor. Mol Pharmacol. 2021 01; 99(1):78-91. Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. PMID: 33109687.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    35. Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors. J Clin Pharmacol. 2021 04; 61(4):531-537. An G, Lee KSS, Yang J, Hammock BD. PMID: 33078430.
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    36. Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 2021; 11(3):815-830. Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG. PMID: 33068774.
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    37. Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease. Neurotherapeutics. 2020 10; 17(4):1825-1835. Griñán-Ferré C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R, Sanfeliu C, Pérez B, Loza MI, Brea J, Morisseau C, Hammock BD, Vázquez S, Pallàs M, Galdeano C. PMID: 32488482.
      View in: PubMed   Mentions: 9     Fields:    
    38. Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity. Int J Mol Sci. 2020 Sep 24; 21(19). Overby H, Yang Y, Xu X, Graham K, Hildreth K, Choi S, Wan D, Morisseau C, Zeldin DC, Hammock BD, Wang S, Bettaieb A, Zhao L. PMID: 32987880.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    39. Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine. Neuropsychopharmacol Rep. 2020 12; 40(4):412-416. Wan X, Fujita Y, Chang L, Wei Y, Ma L, Wuyun G, Pu Y, Hammock BD, Hashimoto K. PMID: 32896112.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    40. Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in a hypertensive model of chronic cerebral hypoperfusion. Microcirculation. 2021 01; 28(1):e12653. Matin N, Fisher C, Lansdell TA, Hammock BD, Yang J, Jackson WF, Dorrance AM. PMID: 32767848.
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    41. Carcinogenesis: Failure of resolution of inflammation? Pharmacol Ther. 2021 02; 218:107670. Fishbein A, Hammock BD, Serhan CN, Panigrahy D. PMID: 32891711.
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    42. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 11 15; 28(22):115735. Lee KSS, Ng JC, Yang J, Hwang SH, Morisseau C, Wagner K, Hammock BD. PMID: 33007552.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci. 2020; 7:580. Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. PMID: 33005645.
      View in: PubMed   Mentions: 1  
    44. 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis. J Med Chem. 2020 09 10; 63(17):9237-9257. Codony S, Pujol E, Pizarro J, Feixas F, Valverde E, Loza MI, Brea JM, Saez E, Oyarzabal J, Pineda-Lucena A, Pérez B, Pérez C, Rodríguez-Franco MI, Leiva R, Osuna S, Morisseau C, Hammock BD, Vázquez-Carrera M, Vázquez S. PMID: 32787085.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    45. Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its contamination in environmental water. Sci Total Environ. 2021 Jan 20; 753:141950. Li ZF, Dong JX, Vasylieva N, Cui YL, Wan DB, Hua XD, Huo JQ, Yang DC, Gee SJ, Hammock BD. PMID: 32906044.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    46. Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. J Nutr Biochem. 2020 12; 86:108484. Hildreth K, Kodani SD, Hammock BD, Zhao L. PMID: 32827665.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    47. Early antihypertensive treatment and ischemia-induced acute kidney injury. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F563-F570. Greite R, Derlin K, Hensen B, Thorenz A, Rong S, Chen R, Hellms S, Jang MS, Bräsen JH, Meier M, Willenberg I, Immenschuh S, Haller H, Luft FC, Panigrahy D, Hwang SH, Hammock BD, Schebb NH, Gueler F. PMID: 32799675.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    48. Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer. Anal Chem. 2020 09 01; 92(17):11654-11663. Li D, Cui Y, Morisseau C, Wagner KM, Cho YS, Hammock BD. PMID: 32786492.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    49. Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21576-21587. Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D. PMID: 32801214.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    50. Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy. Stem Cells Transl Med. 2020 12; 9(12):1570-1584. Sirish P, Thai PN, Lee JH, Yang J, Zhang XD, Ren L, Li N, Timofeyev V, Lee KSS, Nader CE, Rowland DJ, Yechikov S, Ganaga S, Young N, Lieu DK, Yamoah EN, Hammock BD, Chiamvimonvat N. PMID: 32790136.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    51. Generation of functional single-chain fragment variable from hybridoma and development of chemiluminescence enzyme immunoassay for determination of total malachite green in tilapia fish. Food Chem. 2021 Feb 01; 337:127780. Dong J, Li Z, Wang Y, Jin M, Shen Y, Xu Z, Abd El-Aty AM, Gee SJ, Hammock BD, Sun Y, Wang H. PMID: 32799164.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    52. Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats. Int Immunopharmacol. 2020 Oct; 87:106841. Teixeira JM, Abdalla HB, Basting RT, Hammock BD, Napimoga MH, Clemente-Napimoga JT. PMID: 32736189.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    53. Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2020 09 15; 30(18):127430. Burmistrov V, Morisseau C, Karlov D, Pitushkin D, Vernigora A, Rasskazova E, Butov GM, Hammock BD. PMID: 32736212.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    54. Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)? Am J Pathol. 2020 09; 190(9):1782-1788. Hammock BD, Wang W, Gilligan MM, Panigrahy D. PMID: 32650004.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    55. An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion for the Detection of Tetrabromobisphenol A in Sediment. Anal Chem. 2020 07 21; 92(14):10083-10090. Li Z, Wang Y, Vasylieva N, Wan D, Yin Z, Dong J, Hammock BD. PMID: 32559059.
      View in: PubMed   Mentions:    Fields:    Translation:PHPublic Health
    56. Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain. Neurotherapeutics. 2020 07; 17(3):900-916. Wagner KM, Gomes A, McReynolds CB, Hammock BD. PMID: 32875445.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    57. Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? Cancer Metastasis Rev. 2020 06; 39(2):337-340. Panigrahy D, Gilligan MM, Huang S, Gartung A, Cortés-Puch I, Sime PJ, Phipps RP, Serhan CN, Hammock BD. PMID: 32385712.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCellsPHPublic Health
    58. Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model. FASEB J. 2020 07; 34(7):9074-9086. Trindade-da-Silva CA, Clemente-Napimoga JT, Abdalla HB, Rosa SM, Ueira-Vieira C, Morisseau C, Verri WA, Montalli VAM, Hammock BD, Napimoga MH. PMID: 32400048.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    59. Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11753-11759. Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. PMID: 32398374.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsPHPublic Health
    60. Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients. Anal Chem. 2020 05 19; 92(10):7334-7342. Li D, Morisseau C, McReynolds CB, Duflot T, Bellien J, Nagra RM, Taha AY, Hammock BD. PMID: 32253910.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    61. Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis. J Affect Disord. 2020 06 01; 270:131-134. Zhang J, Tan Y, Chang L, Hammock BD, Hashimoto K. PMID: 32339103.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    62. Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide Hydrolase. J Pharmacol Exp Ther. 2020 07; 374(1):223-232. Wu N, Hammock BD, Lee KSS, An G. PMID: 32238455.
      View in: PubMed   Mentions: 3     Fields:    
    63. Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice. Arch Toxicol. 2020 06; 94(6):1995-2007. Pressly B, Vasylieva N, Barnych B, Singh V, Singh L, Bruun DA, Hwang SH, Chen YJ, Fettinger JC, Johnnides S, Lein PJ, Yang J, Hammock BD, Wulff H. PMID: 32239239.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    64. Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation. Proc Natl Acad Sci U S A. 2020 04 14; 117(15):8431-8436. Wang Y, Yang J, Wang W, Sanidad KZ, Cinelli MA, Wan D, Hwang SH, Kim D, Lee KSS, Xiao H, Hammock BD, Zhang G. PMID: 32220957.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    65. A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation. Theranostics. 2020; 10(11):4749-4761. Yang HH, Duan JX, Liu SK, Xiong JB, Guan XX, Zhong WJ, Sun CC, Zhang CY, Luo XQ, Zhang YF, Chen P, Hammock BD, Hwang SH, Jiang JX, Zhou Y, Guan CX. PMID: 32308747.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    66. Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 01; 193:112206. Barnych B, Singh N, Negrel S, Zhang Y, Magis D, Roux C, Hua X, Ding Z, Morisseau C, Tantillo DJ, Siegel JB, Hammock BD. PMID: 32203787.
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    80. A Nanobody Against Cytotoxic T-Lymphocyte Associated Antigen-4 Increases the Anti-Tumor Effects of Specific CD8+ T Cells. J Biomed Nanotechnol. 2019 Nov 01; 15(11):2229-2239. Tang Z, Mo F, Liu A, Duan S, Yang X, Liang L, Hou X, Yin S, Jiang X, Vasylieva N, Dong J, Barnych B, Hammock BD, Lu X. PMID: 31847937.
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    89. 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. ACS Chem Neurosci. 2019 09 18; 10(9):4018-4030. Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. PMID: 31378059.
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    90. Highly Specific Monoclonal Antibody and Sensitive Quantum Dot Beads-Based Fluorescence Immunochromatographic Test Strip for Tebuconazole Assay in Agricultural Products. J Agric Food Chem. 2019 Aug 14; 67(32):9096-9103. Wang Y, Xu J, Qiu Y, Li P, Liu B, Yang L, Barnych B, Hammock BD, Zhang C. PMID: 31356079.
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    129. Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J Med Chem. 2018 05 10; 61(9):4271. Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 29701466.
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    130. Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem. 2018 04 26; 61(8):3541-3550. Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. PMID: 29614224.
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    131. Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere. 2018 Jul; 203:467-473. Bever CS, Rand AA, Nording M, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. PMID: 29635158.
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    132. Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2018 03 27; 8(1):5279. Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 29588470.
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    133. Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther. 2018 06; 365(3):467-475. Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S. PMID: 29567865.
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    134. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat. 2018 05; 136:90-95. Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. PMID: 29567338.
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    135. Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney Blood Press Res. 2018; 43(2):329-349. Certíková Chábová V, Kujal P, Škaroupková P, Varnourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesar V, Cervenka L. PMID: 29529602.
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    136. Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function. J Lipid Res. 2018 04; 59(4):684-695. Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR. PMID: 29459481.
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    137. Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation. J Leukoc Biol. 2018 07; 104(1):109-122. Bastan I, Ge XN, Dileepan M, Greenberg YG, Guedes AG, Hwang SH, Hammock BD, Washabau RJ, Rao SP, Sriramarao P. PMID: 29345370.
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    138. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett. 2018 02 15; 28(4):762-768. Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. PMID: 29366648.
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    139. Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation. Proc Natl Acad Sci U S A. 2018 01 16; 115(3):613-618. Yang YM, Sun D, Kandhi S, Froogh G, Zhuge J, Huang W, Hammock BD, Huang A. PMID: 29295935.
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    140. Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. J Alzheimers Dis. 2018; 62(4):1663-1681. Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Erakovic Haber V, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L. PMID: 29504531.
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    141. LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide. Methods Mol Biol. 2018; 1730:123-133. Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C. PMID: 29363071.
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    142. Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability. Bioorg Chem. 2018 02; 76:510-527. Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD. PMID: 29310082.
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    143. COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. Mol Cancer Ther. 2018 02; 17(2):474-483. Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, de Vere White RW, Pan CX. PMID: 29284644.
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    144. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017 12 14; 552(7684):248-252. Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I. PMID: 29211719.
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    145. Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal. 2018 Feb 05; 149:457-464. Lakkappa N, Krishnamurthy PT, Yamjala K, Hwang SH, Hammock BD, Babu B. PMID: 29169114.
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    146. Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12608-12613. Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY. PMID: 29109264.
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    147. Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts. Anal Biochem. 2017 12 15; 539:81-89. Kodani SD, Barthélemy M, Kamita SG, Hammock B, Morisseau C. PMID: 29054529.
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    148. Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies. Anal Chem. 2017 10 17; 89(20):11091-11097. Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. PMID: 28942640.
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    149. COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor. Oncotarget. 2017 Oct 20; 8(50):87353-87363. Li J, Zhou Y, Wang H, Gao Y, Li L, Hwang SH, Ji X, Hammock BD. PMID: 29152086.
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    150. Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:68-78. Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. PMID: 28847566.
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    151. Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7545-E7553. Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. PMID: 28827330.
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    152. Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2758-2765. Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. PMID: 28757338.
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    153. Postprandial effect to decrease soluble epoxide hydrolase activity: roles of insulin and gut microbiota. J Nutr Biochem. 2017 11; 49:8-14. Yang J, Oh YT, Wan D, Watanabe RM, Hammock BD, Youn JH. PMID: 28863368.
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    154. Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Sci Rep. 2017 06 28; 7(1):4342. Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. PMID: 28659576.
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    155. Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. J Med Chem. 2017 07 13; 60(13):5392-5406. Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRR, Rana S, Contreras JI, Sahoo R, Wan D, Young J, Dias Teixeira KL, Morisseau C, Halperin J, Hammock B, Natarajan A, Wang P, Chorev M, Aktas BH. PMID: 28590739.
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    156. Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases. Pharmacol Ther. 2017 Dec; 180:62-76. Wagner KM, McReynolds CB, Schmidt WK, Hammock BD. PMID: 28642117.
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    157. Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats. Cardiovasc Ther. 2017 Jun; 35(3). Islam O, Patil P, Goswami SK, Razdan R, Inamdar MN, Rizwan M, Mathew J, Inceoglu B, Stephen Lee KS, Hwang SH, Hammock BD. PMID: 28296232.
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    158. Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472. Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. PMID: 28411375.
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    159. Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury. FEBS J. 2017 07; 284(13):1970-1986. Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG. PMID: 28485854.
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    160. Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs. Org Biomol Chem. 2017 May 23; 15(20):4308-4313. Barnych B, Rand AA, Cajka T, Lee KSS, Hammock BD. PMID: 28470279.
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    161. Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers. Life Sci. 2017 Jul 01; 180:114-122. Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD. PMID: 28522175.
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    162. Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP? Anal Chem. 2017 06 06; 89(11):6248-6256. Li D, Cui Y, Morisseau C, Gee SJ, Bever CS, Liu X, Wu J, Hammock BD, Ying Y. PMID: 28460522.
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    163. Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales. PLoS One. 2017; 12(5):e0176571. Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD. PMID: 28472063.
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    164. Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice. Shock. 2017 05; 47(5):638-645. Zhou Y, Liu T, Duan JX, Li P, Sun GY, Liu YP, Zhang J, Dong L, Lee KSS, Hammock BD, Jiang JX, Guan CX. PMID: 27753791.
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    165. EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids. . 2017 08 01; 313(2):L350-L359. Kandhi S, Zhang B, Froogh G, Qin J, Alruwaili N, Le Y, Yang YM, Hwang SH, Hammock BD, Wolin MS, Huang A, Sun D. PMID: 28450284.
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    166. Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine. Anal Chem. 2017 05 16; 89(10):5612-5619. Vasylieva N, Barnych B, Rand A, Inceoglu B, Gee SJ, Hammock BD. PMID: 28398746.
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    167. In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. Drug Metab Dispos. 2017 07; 45(7):712-720. Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z. PMID: 28428366.
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    168. Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids. FASEB J. 2017 08; 31(8):3229-3239. Fiala M, Kooij G, Wagner K, Hammock B, Pellegrini M. PMID: 28420693.
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    169. Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids. Proc Natl Acad Sci U S A. 2017 04 25; 114(17):4370-4375. Rand AA, Barnych B, Morisseau C, Cajka T, Lee KSS, Panigrahy D, Hammock BD. PMID: 28396419.
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    170. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure. 2017 05 02; 25(5):697-707.e4. Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR. PMID: 28392259.
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    171. Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis. J Pharmacol Exp Ther. 2017 06; 361(3):408-416. Trindade-da-Silva CA, Bettaieb A, Napimoga MH, Lee KSS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD. PMID: 28356494.
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    172. Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environ Int. 2017 06; 103:91-98. Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. PMID: 28343720.
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    173. Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behav Brain Res. 2017 05 30; 326:69-76. Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. PMID: 28259677.
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    174. Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study. Psychiatry Res. 2017 06; 252:94-101. Hennebelle M, Otoki Y, Yang J, Hammock BD, Levitt AJ, Taha AY, Swardfager W. PMID: 28259037.
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    175. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1382-1391. Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. PMID: 28185955.
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    176. A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine. J Lipid Res. 2017 04; 58(4):798-808. Wan D, Yang J, Barnych B, Hwang SH, Lee KSS, Cui Y, Niu J, Watsky MA, Hammock BD. PMID: 28148721.
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    177. Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. J Neurochem. 2017 03; 140(5):814-825. Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A. PMID: 28002622.
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    178. Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes. Plast Reconstr Surg Glob Open. 2016 Dec; 4(12):e1151. Supp DM, Hahn JM, McFarland KL, Combs KA, Lee KS, Inceoglu B, Wan D, Boyce ST, Hammock BD. PMID: 28293507.
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    179. Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorg Med Chem Lett. 2017 02 01; 27(3):620-625. Hwang SH, Wagner K, Xu J, Yang J, Li X, Cao Z, Morisseau C, Lee KS, Hammock BD. PMID: 28025003.
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    180. Effects of high-fat diet on plasma profiles of eicosanoid metabolites in mice. Prostaglandins Other Lipid Mediat. 2016 12; 127:9-13. Wang W, Yang J, Yang H, Sanidad KZ, Hammock BD, Kim D, Zhang G. PMID: 27913146.
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    181. Lipidomic profiling of high-fat diet-induced obesity in mice: Importance of cytochrome P450-derived fatty acid epoxides. Obesity (Silver Spring). 2017 01; 25(1):132-140. Wang W, Yang J, Qi W, Yang H, Wang C, Tan B, Hammock BD, Park Y, Kim D, Zhang G. PMID: 27891824.
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    182. Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Arch Biochem Biophys. 2017 Jan 01; 613:1-11. Lee KS, Henriksen NM, Ng CJ, Yang J, Jia W, Morisseau C, Andaya A, Gilson MK, Hammock BD. PMID: 27983948.
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    183. A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents. Mitochondrion. 2016 Nov; 31:79-83. Datta S, Sahdeo S, Gray JA, Morriseau C, Hammock BD, Cortopassi G. PMID: 27717841.
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    184. Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere. 2017 Jan; 166:511-520. Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. PMID: 27710886.
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    185. Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use. J Ethnopharmacol. 2016 Dec 24; 194:475-482. Liu JY, Morisseau C, Huang H, Hammock BD. PMID: 27702689.
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    186. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16; 262:92-99. Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD, Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. PMID: 27659731; PMCID: PMC5096949.
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    187. An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis. J Nutr Biochem. 2016 12; 38:93-101. Harris TR, Kodani S, Yang J, Imai DM, Hammock BD. PMID: 27732914.
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    188. Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol. 2016 Nov 15; 223:923-935. Ghosh R, Goswami SK, Feitoza LFBB, Hammock B, Gomes AV. PMID: 27589040.
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    189. Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice. J Mol Cell Cardiol. 2016 09; 98:128-37. Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan LM, Hammock BD, Ai D, Zhu Y, Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan LM, Hammock BD, Ai D, Zhu Y. PMID: 27496380; PMCID: PMC5559083.
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    190. A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat. Prostaglandins Other Lipid Mediat. 2016 09; 125:40-7. Hye Khan MA, Hwang SH, Sharma A, Corbett JA, Hammock BD, Imig JD. PMID: 27432695.
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    191. Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1919-27. Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellström A, Hammock BD, Zeldin DC, Smith LE, Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellström A, Hammock BD, Zeldin DC, Smith LE. PMID: 27417579; PMCID: PMC5010176.
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    193. Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury. Front Pharmacol. 2016; 7:133. Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM, Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM. PMID: 27375480; PMCID: PMC4896112.
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    194. Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders. Med Hypotheses. 2016 Aug; 93:161-5. Lakkappa N, Krishnamurthy PT, Hammock BD, Velmurugan D, Bharath MM, Lakkappa N, Krishnamurthy PT, Hammock BD, Velmurugan D, Bharath MM. PMID: 27372879; PMCID: PMC4985172.
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    195. Erratum to: Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 06; 364(3):675. Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX, Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26946414.
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    197. VHH antibodies: emerging reagents for the analysis of environmental chemicals. Anal Bioanal Chem. 2016 Sep; 408(22):5985-6002. Bever CS, Dong JX, Vasylieva N, Barnych B, Cui Y, Xu ZL, Hammock BD, Gee SJ, Bever CS, Dong JX, Vasylieva N, Barnych B, Cui Y, Xu ZL, Hammock BD, Gee SJ. PMID: 27209591; PMCID: PMC4983233.
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    198. Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. Int J Mol Sci. 2016 May 18; 17(5). Sharma A, Hye Khan MA, Levick SP, Lee KS, Hammock BD, Imig JD, Sharma A, Hye Khan MA, Levick SP, Lee KS, Hammock BD, Imig JD. PMID: 27213332; PMCID: PMC4881572.
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    199. Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins Leukot Essent Fatty Acids. 2018 11; 138:71-80. Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE. PMID: 27282298.
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    200. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N, Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. PMID: 27162031; PMCID: PMC4869994.
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    201. Quantification of GST and esterase activities in pyrethrin-resistant mosquitoes using pyrethroid-like fluorescent substrates. Int J Pest Manag. 2016; 62(4):276-283. Kamita SG, Mulligan S, Cornel AJ, Hammock BD. PMID: 28736488.
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    202. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61. Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ, Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. PMID: 26937944; PMCID: PMC4821808.
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    203. Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther. 2016 06; 357(3):529-36. Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD, Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. PMID: 26989141; PMCID: PMC4885505.
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    204. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):E1944-52. Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K, Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. PMID: 26976569; PMCID: PMC4822604.
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    205. Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates. Drug Metab Dispos. 2016 May; 44(5):771-80. Zhao Y, Wan D, Yang J, Hammock BD, Ortiz de Montellano PR, Zhao Y, Wan D, Yang J, Hammock BD, Ortiz de Montellano PR. PMID: 26936974; PMCID: PMC4851306.
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    206. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 2016 Mar; 92:30-40. Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C, Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C. PMID: 26812119; PMCID: PMC5008453.
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    207. Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (Lond). 2016 Feb; 11(4):377-90. Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH, Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. PMID: 26786134; PMCID: PMC4910953.
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    208. Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. J Ocul Biol. 2016 Jan; 4(1). McLellan GJ, Aktas Z, Hennes-Beean E, Kolb AW, Larsen IV, Schmitz EJ, Clausius HR, Yang J, Hwang SH, Morisseau C, Inceoglu B, Hammock BD, Brandt CR. PMID: 28066796.
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    209. Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-KrasG¹²D/Pdx-1-Cre Mice. Anticancer Res. 2016 Jan; 36(1):27-37. Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY, Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY. PMID: 26722025; PMCID: PMC4793710.
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    210. Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Lett. 2016 Feb 28; 371(2):187-93. Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY, Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY. PMID: 26683769; PMCID: PMC4738175.
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    211. Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays. Anal Chem. 2015 Dec 01; 87(23):11907-14. Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever CS, Lee KS, Morisseau C, Leizagoyen C, Gee S, Hammock BD, González-Sapienza G, Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever CS, Lee KS, Morisseau C, Leizagoyen C, Gee S, Hammock BD, González-Sapienza G. PMID: 26544909; PMCID: PMC4666776.
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    212. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model. Toxicol Appl Pharmacol. 2015 Dec 15; 289(3):419-27. Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD, Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. PMID: 26522832; PMCID: PMC4666679.
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    213. 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2015 Dec 01; 25(23):5514-9. Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD, Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. PMID: 26520661; PMCID: PMC4654407.
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    214. Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase. Bioorg Med Chem. 2015 Nov 15; 23(22):7199-210. Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K, Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K. PMID: 26507430.
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    215. Effects of juvenile hormone (JH) analog insecticides on larval development and JH esterase activity in two spodopterans. Pestic Biochem Physiol. 2016 Mar; 128:30-6. El-Sheikh el-SA, Kamita SG, Hammock BD, El-Sheikh el-SA, Kamita SG, Hammock BD. PMID: 26969437.
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    216. In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochem Pharmacol. 2015 Dec 15; 98(4):718-31. Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD, Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. PMID: 26494425; PMCID: PMC4656071.
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    218. Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 02; 363(2):399-409. Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX, Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26310139; PMCID: PMC4738109.
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    219. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem. 2015 Sep; 407(24):7263-73. Ranganathan A, Gee SJ, Hammock BD, Ranganathan A, Gee SJ, Hammock BD. PMID: 26255293; PMCID: PMC4580343.
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    220. Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environ Sci Technol. 2015 Aug 18; 49(16):10038-47. Vasylieva N, Ahn KC, Barnych B, Gee SJ, Hammock BD, Vasylieva N, Ahn KC, Barnych B, Gee SJ, Hammock BD. PMID: 26196357; PMCID: PMC4605820.
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    221. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem. 2015 Sep; 407(24):7275-83. Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD, Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD. PMID: 26229025; PMCID: PMC4573264.
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    222. The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. Am J Physiol Renal Physiol. 2015 Sep 15; 309(6):F492-8. Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock B, Bell PD, Guay-Woodford LM, Weiss RH, Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock B, Bell PD, Guay-Woodford LM, Weiss RH. PMID: 26155843; PMCID: PMC4572393.
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    223. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9082-7. Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD, Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. PMID: 26150506; PMCID: PMC4517273.
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    224. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat. 2015 Sep; 121(Pt A):131-7. Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH, Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. PMID: 26117215; PMCID: PMC4688279.
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    228. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ, Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. PMID: 25882826; PMCID: PMC4466064.
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    232. Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection. J Insect Physiol. 2015 Sep; 80:71-80. Saito Y, Kamita SG, Hammock BD, Kunimi Y, Inoue MN, Nakai M, Saito Y, Kamita SG, Hammock BD, Kunimi Y, Inoue MN, Nakai M. PMID: 25727179.
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    235. Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. Insect Biochem Mol Biol. 2015 Apr; 59:41-9. Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD, Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD. PMID: 25686802; PMCID: PMC4387068.
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    238. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):536-41. López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J. PMID: 25550510; PMCID: PMC4299190.
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    241. Identification of potent inhibitors of the chicken soluble epoxide hydrolase. Bioorg Med Chem Lett. 2015 Jan 15; 25(2):276-9. Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C, Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. PMID: 25479771; PMCID: PMC4277729.
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    242. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemother Pharmacol. 2015 Jan; 75(1):161-71. Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD, Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. PMID: 25413440; PMCID: PMC4400119.
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    243. Editorial: 15th International Winter Eicosanoid Conference. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:1. Panigrahy D, Hammock B, Panigrahy D, Hammock B. PMID: 25453874.
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    244. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. PLoS One. 2014; 9(11):e113019. Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG, Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. PMID: 25402489; PMCID: PMC4234494.
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    245. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17200-5. Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH, Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. PMID: 25404284; PMCID: PMC4260592.
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    246. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol. 2015 Jan-Feb; 47:36-45. Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ, Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ. PMID: 25446016; PMCID: PMC4291292.
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    247. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics. 2014 Nov; 8(6):064101. Chen A, Wang R, Bever CR, Xing S, Hammock BD, Pan T, Chen A, Wang R, Bever CR, Xing S, Hammock BD, Pan T. PMID: 25553178; PMCID: PMC4241779.
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    248. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. Am J Physiol Renal Physiol. 2015 Jan 15; 308(2):F131-9. Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ, Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. PMID: 25377915; PMCID: PMC4338924.
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    249. Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):886-97. Ono E, Dutile S, Kazani S, Wechsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland ER, Castro M, Jarjour NN, Israel E, Levy BD, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network , Ono E, Dutile S, Kazani S, Wechsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland ER, Castro M, Jarjour NN, Israel E, Levy BD, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 25162465; PMCID: PMC4299578.
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    250. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicol Appl Pharmacol. 2014 Dec 01; 281(2):185-94. Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ, Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. PMID: 25448683; PMCID: PMC4258121.
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    251. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicol Lett. 2015 Jan 05; 232(1):10-20. Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM, Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM. PMID: 25300478; PMCID: PMC4486642.
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    252. The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:2-12. Wagner K, Vito S, Inceoglu B, Hammock BD, Wagner K, Vito S, Inceoglu B, Hammock BD. PMID: 25240260; PMCID: PMC4254344.
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    253. Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model. J Vasc Res. 2014; 51(4):269-82. Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK, Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK. PMID: 25196102; PMCID: PMC4235611.
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    254. Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. Am J Physiol Renal Physiol. 2014 Oct 15; 307(8):F971-80. Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ, Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ. PMID: 25164080; PMCID: PMC4200297.
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    255. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. J Am Heart Assoc. 2014 Aug 21; 3(4). Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F, Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. PMID: 25146704; PMCID: PMC4310392.
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    256. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 2014 Aug 28; 57(16):7016-30. Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD, Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 25079952; PMCID: PMC4148150.
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    257. Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3062-71. Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, Green MR, Wajapeyee N, Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, Green MR, Wajapeyee N. PMID: 25024194; PMCID: PMC4121806.
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    258. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):11127-32. Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD, Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 25024195; PMCID: PMC4121808.
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    259. ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:13-20. Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G, Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G. PMID: 25019221; PMCID: PMC4306447.
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    260. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal Chem. 2014 Aug 05; 86(15):7875-82. Bever CR, Majkova Z, Radhakrishnan R, Suni I, McCoy M, Wang Y, Dechant J, Gee S, Hammock BD, Bever CR, Majkova Z, Radhakrishnan R, Suni I, McCoy M, Wang Y, Dechant J, Gee S, Hammock BD. PMID: 25005746; PMCID: PMC4144723.
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    261. Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core. Eur J Med Chem. 2014 Sep 12; 84:160-72. Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M, Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. PMID: 25016374.
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    262. An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2014 Jul; 64(1):87-99. Ulu A, Stephen Lee KS, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD, Ulu A, Stephen Lee KS, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD. PMID: 24691274; PMCID: PMC4092041.
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    263. Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. J Pain. 2014 Sep; 15(9):907-14. Wagner K, Yang J, Inceoglu B, Hammock BD, Wagner K, Yang J, Inceoglu B, Hammock BD. PMID: 24924124; PMCID: PMC4150748.
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    264. GABAA receptor target of tetramethylenedisulfotetramine. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8607-12. Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone FC, Lightstone F, Yang J, Hammock BD, Casida JE, Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone FC, Lightstone F, Yang J, Hammock BD, Casida JE. PMID: 24912155; PMCID: PMC4060666.
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    265. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8167-72. Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P, Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. PMID: 24843165; PMCID: PMC4050620.
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    266. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. J Lipid Res. 2014 06; 55(6):1131-8. Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD, Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. PMID: 24771868; PMCID: PMC4031944.
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    267. Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts. Drug Metab Dispos. 2014 Jul; 42(7):1098-102. Schebb NH, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH, Schebb NH, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH. PMID: 24733789; PMCID: PMC4170114.
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    268. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environ Res. 2014 May; 131:153-9. Trunnelle KJ, Bennett DH, Ahn KC, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD, Trunnelle KJ, Bennett DH, Ahn KC, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD. PMID: 24721133; PMCID: PMC4152318.
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    269. Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis. PLoS One. 2014; 9(4):e94092. Li L, Li N, Pang W, Zhang X, Hammock BD, Ai D, Zhu Y, Li L, Li N, Pang W, Zhang X, Hammock BD, Ai D, Zhu Y. PMID: 24718617; PMCID: PMC3981766.
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    270. Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats. J Pharm Pharmacol. 2014 Sep; 66(9):1251-8. Shrestha A, Krishnamurthy PT, Thomas P, Hammock BD, Hwang SH, Shrestha A, Krishnamurthy PT, Thomas P, Hammock BD, Hwang SH. PMID: 24697323; PMCID: PMC4134728.
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    271. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 2014 Apr; 25(4):433-46. Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD, Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. PMID: 24525589; PMCID: PMC3947856.
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    272. Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2014 May 01; 24(9):2193-7. Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD, Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD. PMID: 24685540; PMCID: PMC4019751.
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    273. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clin Exp Pharmacol Physiol. 2014 Mar; 41(3):227-37. Kujal P, Certíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Cervenka L, Kujal P, Certíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Cervenka L. PMID: 24471737; PMCID: PMC4038339.
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    274. Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure. Am J Physiol Heart Circ Physiol. 2014 Apr 15; 306(8):H1146-53. Sun D, Cuevas AJ, Gotlinger K, Hwang SH, Hammock BD, Schwartzman ML, Huang A, Sun D, Cuevas AJ, Gotlinger K, Hwang SH, Hammock BD, Schwartzman ML, Huang A. PMID: 24561863; PMCID: PMC3989753.
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    275. Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase. Bioorg Med Chem. 2014 Feb 01; 22(3):1163-75. Kim IH, Lee IH, Nishiwaki H, Hammock BD, Nishi K, Kim IH, Lee IH, Nishiwaki H, Hammock BD, Nishi K. PMID: 24433964; PMCID: PMC4172381.
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    276. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Prog Lipid Res. 2014 Jan; 53:108-23. Zhang G, Kodani S, Hammock BD, Zhang G, Kodani S, Hammock BD. PMID: 24345640; PMCID: PMC3914417.
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    277. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One. 2013; 8(12):e80922. Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD, Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. PMID: 24349022; PMCID: PMC3862847.
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    278. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Res. 2013 Dec; 33(12):5261-5271. Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang GY, Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang GY. PMID: 24324059; PMCID: PMC4076172.
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    279. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. J Med Chem. 2013 Dec 12; 56(23):9457-70. Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH, Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH. PMID: 24261904; PMCID: PMC3938169.
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    280. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One. 2013; 8(10):e76575. Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM, Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. PMID: 24204640; PMCID: PMC3811983.
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    281. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int. 2013 Nov; 61:57-63. Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB, Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. PMID: 24096042; PMCID: PMC4059492.
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    282. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. J Exp Biol. 2013 Dec 15; 216(Pt 24):4615-25. Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D, Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D. PMID: 24072790; PMCID: PMC3851147.
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    283. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. Am J Physiol Heart Circ Physiol. 2013 Dec 01; 305(11):H1605-13. Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM, Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM. PMID: 24043255; PMCID: PMC3882464.
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    284. Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2013 Sep; 62(3):285-97. Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD, Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. PMID: 23676336; PMCID: PMC3773051.
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    285. Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins Leukot Essent Fatty Acids. 2013 Oct; 89(5):351-8. Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ, Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ. PMID: 24055573; PMCID: PMC3897272.
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    286. Aging, estrogen loss and epoxyeicosatrienoic acids (EETs). PLoS One. 2013; 8(8):e70719. Lee AR, Pechenino AS, Dong H, Hammock BD, Knowlton AA, Lee AR, Pechenino AS, Dong H, Hammock BD, Knowlton AA. PMID: 23967089; PMCID: PMC3742755.
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    287. Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13528-33. Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW, Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. PMID: 23898174; PMCID: PMC3746918.
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    288. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem. 2013 Jul 17; 61(28):6964-70. Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD, Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. PMID: 23767873; PMCID: PMC3723731.
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    289. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res. 2013 Aug; 57(8):1319-35. Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB, Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB. PMID: 23818328; PMCID: PMC3806310.
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    290. Characterization of Hovi-mEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis. Arch Insect Biochem Physiol. 2013 Aug; 83(4):171-9. Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety RS, Falk BW, Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety RS, Falk BW. PMID: 23704009; PMCID: PMC3846607.
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    291. Soluble epoxide hydrolase: gene structure, expression and deletion. Gene. 2013 Sep 10; 526(2):61-74. Harris TR, Hammock BD, Harris TR, Hammock BD. PMID: 23701967; PMCID: PMC3733540.
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    292. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3732-7. Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD, Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. PMID: 23726028; PMCID: PMC3744640.
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    293. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3818-21. Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD, Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. PMID: 23684894; PMCID: PMC3703951.
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    294. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sci. 2013 Jun 21; 92(23):1145-50. Poli G, Corda E, Martino PA, Dall'ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B, Poli G, Corda E, Martino PA, Dall'ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. PMID: 23651659; PMCID: PMC3806320.
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    295. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem. 2013 May 17; 288(20):14189-14199. Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG, Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. PMID: 23576437; PMCID: PMC3656275.
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    296. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6530-5. Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD, Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 23553837; PMCID: PMC3631682.
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    297. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clin Exp Pharmacol Physiol. 2013 Apr; 40(4):273-81. Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L, Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. PMID: 23039246; PMCID: PMC3769696.
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    298. Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy. Br J Pharmacol. 2013 Apr; 168(8):1794-807. Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO, Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO. PMID: 23176298; PMCID: PMC3623051.
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    299. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5618-23. Sirish P, Li N, Liu JY, Lee KS, Hwang SH, Qiu H, Zhao C, Ma SM, López JE, Hammock BD, Chiamvimonvat N, Sirish P, Li N, Liu JY, Lee KS, Hwang SH, Qiu H, Zhao C, Ma SM, López JE, Hammock BD, Chiamvimonvat N. PMID: 23493561; PMCID: PMC3619365.
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    300. Photonic crystal lab-on-a-chip for detecting staphylococcal enterotoxin B at low attomolar concentration. Anal Chem. 2013 Mar 19; 85(6):3104-9. Han JH, Kim HJ, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM, Han JH, Kim HJ, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. PMID: 23418954; PMCID: PMC3608201.
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    301. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg. 2013 Jul; 40(4):440-8. Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD, Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. PMID: 23463912; PMCID: PMC3956586.
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    302. Carbon turnover in the water-soluble protein of the adult human lens. Mol Vis. 2013; 19:463-75. Stewart DN, Lango J, Nambiar KP, Falso MJ, FitzGerald PG, Rocke DM, Hammock BD, Buchholz BA, Stewart DN, Lango J, Nambiar KP, Falso MJ, FitzGerald PG, Rocke DM, Hammock BD, Buchholz BA. PMID: 23441119; PMCID: PMC3580966.
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    303. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. J Hypertens. 2013 Feb; 31(2):321-32. Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Cervenka L, Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Cervenka L. PMID: 23307303; PMCID: PMC3773167.
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    304. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol Ther. 2013 Mar; 14(3):278-85. Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH, Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. PMID: 23298903; PMCID: PMC3595311.
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    305. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013 Mar 12; 48(4-5):619-27. Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD, Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. PMID: 23291046; PMCID: PMC3596469.
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    306. Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties. Nat Commun. 2013; 4:1840. de Medina P, Paillasse MR, Segala G, Voisin M, Mhamdi L, Dalenc F, Lacroix-Triki M, Filleron T, Pont F, Saati TA, Morisseau C, Hammock BD, Silvente-Poirot S, Poirot M, de Medina P, Paillasse MR, Segala G, Voisin M, Mhamdi L, Dalenc F, Lacroix-Triki M, Filleron T, Pont F, Saati TA, Morisseau C, Hammock BD, Silvente-Poirot S, Poirot M. PMID: 23673625; PMCID: PMC3674249.
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    307. Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. J Toxicol Sci. 2013; 38(6):833-6. Yang J, Solaimani P, Dong H, Hammock B, Hankinson O, Yang J, Solaimani P, Dong H, Hammock B, Hankinson O. PMID: 24213002; PMCID: PMC4068614.
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    308. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. Eur J Pharmacol. 2013 Jan 30; 700(1-3):93-101. Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD, Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. PMID: 23276668; PMCID: PMC3578047.
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    309. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochem Mol Biol. 2013 Mar; 43(3):219-28. Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD, Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. PMID: 23276675; PMCID: PMC3577957.
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    310. Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model. Prostaglandins Other Lipid Mediat. 2013 Jul-Aug; 104-105:42-8. Chen L, Fan C, Zhang Y, Bakri M, Dong H, Morisseau C, Maddipati KR, Luo P, Wang CY, Hammock BD, Wang MH, Chen L, Fan C, Zhang Y, Bakri M, Dong H, Morisseau C, Maddipati KR, Luo P, Wang CY, Hammock BD, Wang MH. PMID: 23247129; PMCID: PMC4052893.
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    311. Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Anal Biochem. 2013 Mar 15; 434(2):259-68. Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD, Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. PMID: 23219719; PMCID: PMC3632402.
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    312. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Anal Biochem. 2013 Mar 01; 434(1):105-11. Morisseau C, Sahdeo S, Cortopassi G, Hammock BD, Morisseau C, Sahdeo S, Cortopassi G, Hammock BD. PMID: 23219563; PMCID: PMC3557602.
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    313. Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2013 Jan 15; 23(2):417-21. Pecic S, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD, Zhu Z, Rinderspacher A, Deng SX, Pecic S, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD, Zhu Z, Rinderspacher A, Deng SX. PMID: 23237835; PMCID: PMC3541548.
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    314. Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Exp Biol Med (Maywood). 2012 Dec; 237(12):1402-12. Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD, Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD. PMID: 23354399; PMCID: PMC3613242.
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    315. Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations. Metabolomics. 2012 Dec; 8(6):1102-1113. Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD, Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. PMID: 23833568; PMCID: PMC3700377.
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    316. Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo. J Lipid Res. 2013 Feb; 54(2):436-47. Kundu S, Roome T, Bhattacharjee A, Carnevale KA, Yakubenko VP, Zhang R, Hwang SH, Hammock BD, Cathcart MK, Kundu S, Roome T, Bhattacharjee A, Carnevale KA, Yakubenko VP, Zhang R, Hwang SH, Hammock BD, Cathcart MK. PMID: 23160182; PMCID: PMC3588870.
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    317. Upregulation of soluble epoxide hydrolase in proximal tubular cells mediated proteinuria-induced renal damage. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F168-76. Wang Q, Pang W, Cui Z, Shi J, Liu Y, Liu B, Zhou Y, Guan Y, Hammock BD, Wang Y, Zhu Y, Wang Q, Pang W, Cui Z, Shi J, Liu Y, Liu B, Zhou Y, Guan Y, Hammock BD, Wang Y, Zhu Y. PMID: 23152298; PMCID: PMC3543623.
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    318. Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures. Chromatographia. 2013 Jan 01; 76(1-2):13-21. Falck D, Schebb NH, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM, Falck D, Schebb NH, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM. PMID: 23526703; PMCID: PMC3601784.
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    319. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol. 2013; 53:37-58. Morisseau C, Hammock BD, Morisseau C, Hammock BD. PMID: 23020295; PMCID: PMC3578707.
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    320. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase. Anal Biochem. 2012 Dec 15; 431(2):77-83. Huang H, Yao H, Liu JY, Samra AI, Kamita SG, Cornel AJ, Hammock BD, Huang H, Yao H, Liu JY, Samra AI, Kamita SG, Cornel AJ, Hammock BD. PMID: 23000005; PMCID: PMC3489985.
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    321. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano. 2012 Oct 23; 6(10):8570-82. Han JH, Sudheendra L, Kim HJ, Gee SJ, Hammock BD, Kennedy IM, Han JH, Sudheendra L, Kim HJ, Gee SJ, Hammock BD, Kennedy IM. PMID: 22957818; PMCID: PMC3479307.
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    322. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron. 2013 Mar 15; 41:302-8. Han JH, Kim HJ, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM, Han JH, Kim HJ, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. PMID: 23021853; PMCID: PMC3525773.
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    323. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kidney Blood Press Res. 2012; 35(6):595-607. Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Cervenka L, Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Cervenka L. PMID: 22948718; PMCID: PMC3604982.
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    324. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN, Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. PMID: 22889812; PMCID: PMC3529644.
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    325. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14158-63. Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN, Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. PMID: 22891308; PMCID: PMC3435154.
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    326. Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats. Am J Physiol Heart Circ Physiol. 2012 Oct 01; 303(7):H853-62. Guglielmino K, Jackson K, Harris TR, Vu V, Dong H, Dutrow G, Evans JE, Graham J, Cummings BP, Havel PJ, Chiamvimonvat N, Despa S, Hammock BD, Despa F, Guglielmino K, Jackson K, Harris TR, Vu V, Dong H, Dutrow G, Evans JE, Graham J, Cummings BP, Havel PJ, Chiamvimonvat N, Despa S, Hammock BD, Despa F. PMID: 22865388; PMCID: PMC3469704.
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    327. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett. 2012 Sep 15; 22(18):5889-92. Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD, Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. PMID: 22901393; PMCID: PMC3432147.
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    328. EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. J Lipid Res. 2012 Oct; 53(10):2038-2045. Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC, Arand M, Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC, Arand M. PMID: 22798687; PMCID: PMC3435537.
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    329. Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. J Cardiovasc Pharmacol. 2012 Jul; 60(1):70-5. Inceoglu AB, Clifton HL, Yang J, Hegedus C, Hammock BD, Schaefer S, Inceoglu AB, Clifton HL, Yang J, Hegedus C, Hammock BD, Schaefer S. PMID: 22526297; PMCID: PMC3396292.
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    330. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11390-5. Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD, Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. PMID: 22733772; PMCID: PMC3396532.
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    331. Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia. Cardiovasc Res. 2012 Aug 01; 95(3):336-45. Qiu H, Liu JY, Wei D, Li N, Yamoah EN, Hammock BD, Chiamvimonvat N, Qiu H, Liu JY, Wei D, Li N, Yamoah EN, Hammock BD, Chiamvimonvat N. PMID: 22707158; PMCID: PMC3400359.
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    332. Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice. PLoS One. 2012; 7(6):e39165. Liu Y, Dang H, Li D, Pang W, Hammock BD, Zhu Y, Liu Y, Dang H, Li D, Pang W, Hammock BD, Zhu Y. PMID: 22720061; PMCID: PMC3375303.
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    333. Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9995-10000. Frömel T, Jungblut B, Hu J, Trouvain C, Barbosa-Sicard E, Popp R, Liebner S, Dimmeler S, Hammock BD, Fleming I, Frömel T, Jungblut B, Hu J, Trouvain C, Barbosa-Sicard E, Popp R, Liebner S, Dimmeler S, Hammock BD, Fleming I. PMID: 22665795; PMCID: PMC3382493.
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    334. Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension. Clin Sci (Lond). 2012 Jun; 122(11):513-25. Neckár J, Kopkan L, Husková Z, Kolár F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Oštádal B, Cervenka L, Neckár J, Kopkan L, Husková Z, Kolár F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Oštádal B, Cervenka L. PMID: 22324471; PMCID: PMC3528350.
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    335. Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation. Curr Eye Res. 2012 Oct; 37(10):871-8. Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA, Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA. PMID: 22632164; PMCID: PMC3572765.
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    336. Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adults. J Nutr. 2012 Jul; 142(7):1246-52. Stephensen CB, Zerofsky M, Burnett DJ, Lin YP, Hammock BD, Hall LM, McHugh T, Stephensen CB, Zerofsky M, Burnett DJ, Lin YP, Hammock BD, Hall LM, McHugh T. PMID: 22623385.
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    337. Soluble epoxide hydrolase expression in a porcine model of arteriovenous graft stenosis and anti-inflammatory effects of a soluble epoxide hydrolase inhibitor. Am J Physiol Cell Physiol. 2012 Aug 01; 303(3):C278-90. Sanders WG, Morisseau C, Hammock BD, Cheung AK, Terry CM, Sanders WG, Morisseau C, Hammock BD, Cheung AK, Terry CM. PMID: 22621785; PMCID: PMC3423029.
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    338. Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Dig Dis Sci. 2012 Oct; 57(10):2580-91. Zhang W, Yang AL, Liao J, Li H, Dong H, Chung YT, Bai H, Matkowskyj KA, Hammock BD, Yang GY, Zhang W, Yang AL, Liao J, Li H, Dong H, Chung YT, Bai H, Matkowskyj KA, Hammock BD, Yang GY. PMID: 22588244; PMCID: PMC3664520.
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    339. Monitoring of total type ii pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. J Agric Food Chem. 2012 May 23; 60(20):5065-70. McCoy MR, Yang Z, Fu X, Ahn KC, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD, McCoy MR, Yang Z, Fu X, Ahn KC, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. PMID: 22486225; PMCID: PMC3412423.
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    340. Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients. Free Radic Biol Med. 2012 Jul 01; 53(1):160-71. Yang J, Eiserich JP, Cross CE, Morrissey BM, Hammock BD, Yang J, Eiserich JP, Cross CE, Morrissey BM, Hammock BD. PMID: 22580336; PMCID: PMC3412514.
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    341. A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction. Int J Cardiol. 2013 Aug 20; 167(4):1298-304. Xu DY, Davis BB, Wang ZH, Zhao SP, Wasti B, Liu ZL, Li N, Morisseau C, Chiamvimonvat N, Hammock BD, Xu DY, Davis BB, Wang ZH, Zhao SP, Wasti B, Liu ZL, Li N, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 22525341; PMCID: PMC3821736.
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    342. Reduction of inflammatory bowel disease-induced tumor development in IL-10 knockout mice with soluble epoxide hydrolase gene deficiency. Mol Carcinog. 2013 Sep; 52(9):726-38. Zhang W, Liao J, Li H, Dong H, Bai H, Yang A, Hammock BD, Yang GY, Zhang W, Liao J, Li H, Dong H, Bai H, Yang A, Hammock BD, Yang GY. PMID: 22517541; PMCID: PMC3407328.
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    343. Structure-based optimization of the piperazino-containing 1,3-disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase. Medchemcomm. 2012 Mar 01; (3):379-384. Huang SX, Cao B, Morisseau C, Jin Y, Hammock BD, Long YQ, Huang SX, Cao B, Morisseau C, Jin Y, Hammock BD, Long YQ. PMID: 25225606; PMCID: PMC4163146.
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    344. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochem Biophys Res Commun. 2012 Mar 23; 419(4):796-800. Morisseau C, Schebb NH, Dong H, Ulu A, Aronov PA, Hammock BD, Morisseau C, Schebb NH, Dong H, Ulu A, Aronov PA, Hammock BD. PMID: 22387545; PMCID: PMC3313618.
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    345. Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Circ Res. 2012 Mar 16; 110(6):808-17. Zhang D, Xie X, Chen Y, Hammock BD, Kong W, Zhu Y, Zhang D, Xie X, Chen Y, Hammock BD, Kong W, Zhu Y. PMID: 22354938; PMCID: PMC3514454.
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    346. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther. 2012 May; 341(2):435-46. Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA, Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. PMID: 22328574; PMCID: PMC3336809.
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    347. Cloning and characterization of two glutathione S-transferases from pyrethroid-resistant Culex pipiens. Pest Manag Sci. 2012 May; 68(5):764-72. Samra AI, Kamita SG, Yao HW, Cornel AJ, Hammock BD, Samra AI, Kamita SG, Yao HW, Cornel AJ, Hammock BD. PMID: 22290868; PMCID: PMC3583349.
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    348. Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications. J Med Chem. 2012 Mar 08; 55(5):1789-808. Shen HC, Hammock BD, Shen HC, Hammock BD. PMID: 22168898; PMCID: PMC3420824.
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    349. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem. 2012 01 17; 84(2):1165-71. Kim HJ, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, González-Sapienza GG, Hammock BD, Kim HJ, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, González-Sapienza GG, Hammock BD. PMID: 22148739; PMCID: PMC3264785.
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    350. Use of a soluble epoxide hydrolase inhibitor in smoke-induced chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2012 May; 46(5):614-22. Wang L, Yang J, Guo L, Uyeminami D, Dong H, Hammock BD, Pinkerton KE, Wang L, Yang J, Guo L, Uyeminami D, Dong H, Hammock BD, Pinkerton KE. PMID: 22180869; PMCID: PMC3359909.
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    351. Corncob bedding alters the effects of estrogens on aggressive behavior and reduces estrogen receptor-α expression in the brain. Endocrinology. 2012 Feb; 153(2):949-53. Villalon Landeros R, Morisseau C, Yoo HJ, Fu SH, Hammock BD, Trainor BC, Villalon Landeros R, Morisseau C, Yoo HJ, Fu SH, Hammock BD, Trainor BC. PMID: 22186416; PMCID: PMC3275391.
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    352. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest. 2012 Jan; 122(1):178-91. Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC, Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC. PMID: 22182838; PMCID: PMC3248288.
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    353. Juvenile hormone (JH) esterase of the mosquito Culex quinquefasciatus is not a target of the JH analog insecticide methoprene. PLoS One. 2011; 6(12):e28392. Kamita SG, Samra AI, Liu JY, Cornel AJ, Hammock BD, Kamita SG, Samra AI, Liu JY, Cornel AJ, Hammock BD. PMID: 22174797; PMCID: PMC3235118.
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    354. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Environ Sci Technol. 2012 Jan 03; 46(1):374-81. Ahn KC, Kasagami T, Tsai HJ, Schebb NH, Ogunyoku T, Gee SJ, Young TM, Hammock BD, Ahn KC, Kasagami T, Tsai HJ, Schebb NH, Ogunyoku T, Gee SJ, Young TM, Hammock BD. PMID: 22077920; PMCID: PMC3258304.
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    355. N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase. Cardiovasc Res. 2012 Jan 01; 93(1):120-9. Hou HH, Hammock BD, Su KH, Morisseau C, Kou YR, Imaoka S, Oguro A, Shyue SK, Zhao JF, Lee TS, Hou HH, Hammock BD, Su KH, Morisseau C, Kou YR, Imaoka S, Oguro A, Shyue SK, Zhao JF, Lee TS. PMID: 22072631; PMCID: PMC3243038.
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    356. Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biol Ther. 2011 Nov 01; 12(9):827-36. Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH, Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH. PMID: 21878748; PMCID: PMC3225758.
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    357. Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett. 2012 Jan 01; 22(1):601-5. Pecic S, Deng SX, Morisseau C, Hammock BD, Landry DW, Pecic S, Deng SX, Morisseau C, Hammock BD, Landry DW. PMID: 22079754; PMCID: PMC3337727.
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    358. Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats. Exp Diabetes Res. 2012; 2012:758614. Iyer A, Kauter K, Alam MA, Hwang SH, Morisseau C, Hammock BD, Brown L, Iyer A, Kauter K, Alam MA, Hwang SH, Morisseau C, Hammock BD, Brown L. PMID: 22007192; PMCID: PMC3191770.
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    359. The soluble epoxide hydrolase as a pharmaceutical target for pain management. Pain Manag. 2011 Sep; 1(5):383-6. Hammock BD, Wagner K, Inceoglu B, Hammock BD, Wagner K, Inceoglu B. PMID: 24645702.
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    360. Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception. Prostaglandins Other Lipid Mediat. 2011 Nov; 96(1-4):76-83. Wagner K, Inceoglu B, Hammock BD, Wagner K, Inceoglu B, Hammock BD. PMID: 21854866; PMCID: PMC3215909.
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    361. Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats. J Hypertens. 2011 Aug; 29(8):1590-601. Honetschlägerová Z, Sporková A, Kopkan L, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Chábová VC, Tesar V, Cervenka L, Honetschlägerová Z, Sporková A, Kopkan L, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Chábová VC, Tesar V, Cervenka L. PMID: 21720266; PMCID: PMC3777565.
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    362. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Anal Bioanal Chem. 2011 Sep; 401(4):1285-93. Ahn KC, Gee SJ, Kim HJ, Aronov PA, Vega H, Krieger RI, Hammock BD, Ahn KC, Gee SJ, Kim HJ, Aronov PA, Vega H, Krieger RI, Hammock BD. PMID: 21717113; PMCID: PMC3848323.
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    363. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicol Appl Pharmacol. 2011 Sep 01; 255(2):200-6. Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD, Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. PMID: 21741984; PMCID: PMC3156297.
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    364. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochem Biophys Res Commun. 2011 Jul 08; 410(3):494-500. Davis BB, Liu JY, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE, Davis BB, Liu JY, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE. PMID: 21683067; PMCID: PMC3166856.
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    365. Profiling the regulatory lipids: another systemic way to unveil the biological mystery. Curr Opin Lipidol. 2011 Jun; 22(3):197-203. Yang J, Dong H, Hammock BD, Yang J, Dong H, Hammock BD. PMID: 21537174; PMCID: PMC3498048.
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    366. Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H373-81. Liu X, Li C, Gebremedhin D, Hwang SH, Hammock BD, Falck JR, Roman RJ, Harder DR, Koehler RC, Liu X, Li C, Gebremedhin D, Hwang SH, Hammock BD, Falck JR, Roman RJ, Harder DR, Koehler RC. PMID: 21602473; PMCID: PMC3154671.
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    367. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9038-43. Luria A, Bettaieb A, Xi Y, Shieh GJ, Liu HC, Inoue H, Tsai HJ, Imig JD, Haj FG, Hammock BD, Luria A, Bettaieb A, Xi Y, Shieh GJ, Liu HC, Inoue H, Tsai HJ, Imig JD, Haj FG, Hammock BD. PMID: 21571638; PMCID: PMC3107315.
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    368. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal Bioanal Chem. 2011 May; 400(5):1359-66. Schebb NH, Huby M, Morisseau C, Hwang SH, Hammock BD, Schebb NH, Huby M, Morisseau C, Hwang SH, Hammock BD. PMID: 21479549; PMCID: PMC3081056.
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    369. Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. J Med Chem. 2011 Apr 28; 54(8):3037-50. Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD, Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. PMID: 21434686; PMCID: PMC3281519.
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    370. Soluble epoxide hydrolase inhibitors and heart failure. Cardiovasc Ther. 2011 Apr; 29(2):99-111. Qiu H, Li N, Liu JY, Harris TR, Hammock BD, Chiamvimonvat N, Qiu H, Li N, Liu JY, Harris TR, Hammock BD, Chiamvimonvat N. PMID: 20433684; PMCID: PMC3325372.
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    371. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6):R1468-75. Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Cervenka L, Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Cervenka L. PMID: 21411763; PMCID: PMC3119161.
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    372. Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2011 Jun; 300(6):H1990-6. Jiang H, Quilley J, Doumad AB, Zhu AG, Falck JR, Hammock BD, Stier CT, Carroll MA, Jiang H, Quilley J, Doumad AB, Zhu AG, Falck JR, Hammock BD, Stier CT, Carroll MA. PMID: 21398593; PMCID: PMC3119086.
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    373. Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects. Environ Sci Technol. 2011 Apr 01; 45(7):3109-15. Schebb NH, Inceoglu B, Ahn KC, Morisseau C, Gee SJ, Hammock BD, Schebb NH, Inceoglu B, Ahn KC, Morisseau C, Gee SJ, Hammock BD. PMID: 21381656; PMCID: PMC3470465.
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    374. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):5093-7. Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD, Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. PMID: 21383170; PMCID: PMC3064364.
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    375. Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene. J Cardiovasc Pharmacol. 2011 Mar; 57(3):273-81. Aboutabl ME, Zordoky BN, Hammock BD, El-Kadi AO, Aboutabl ME, Zordoky BN, Hammock BD, El-Kadi AO. PMID: 21383588.
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    376. Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies. Anal Biochem. 2011 Jul 01; 414(1):154-62. Morisseau C, Bernay M, Escaich A, Sanborn JR, Lango J, Hammock BD, Morisseau C, Bernay M, Escaich A, Sanborn JR, Lango J, Hammock BD. PMID: 21371418; PMCID: PMC3090455.
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    377. Structure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase. J Med Chem. 2011 Mar 24; 54(6):1752-61. Kim IH, Park YK, Hammock BD, Nishi K, Kim IH, Park YK, Hammock BD, Nishi K. PMID: 21338111; PMCID: PMC3517215.
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    378. Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease. Congest Heart Fail. 2011 Jan-Feb; 17(1):42-6. Li N, Liu JY, Qiu H, Harris TR, Sirish P, Hammock BD, Chiamvimonvat N, Li N, Liu JY, Qiu H, Harris TR, Sirish P, Hammock BD, Chiamvimonvat N. PMID: 21272227; PMCID: PMC3583533.
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    379. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. Am J Physiol Endocrinol Metab. 2011 Apr; 300(4):E691-8. Koeners MP, Wesseling S, Ulu A, Sepúlveda RL, Morisseau C, Braam B, Hammock BD, Joles JA, Koeners MP, Wesseling S, Ulu A, Sepúlveda RL, Morisseau C, Braam B, Hammock BD, Joles JA. PMID: 21266668; PMCID: PMC3074945.
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    380. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. J Neurochem. 2011 May; 117(4):632-42. Abdu E, Bruun DA, Yang D, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ, Abdu E, Bruun DA, Yang D, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. PMID: 21155804; PMCID: PMC3081369.
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    381. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. J Physiol. 2011 Jan 01; 589(Pt 1):207-19. Honetschlägerová Z, Husková Z, Vanourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Cervenka L, Kopkan L, Honetschlägerová Z, Husková Z, Vanourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Cervenka L, Kopkan L. PMID: 21078594; PMCID: PMC3039270.
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    382. Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies. Anal Methods. 2011 Jan 01; 3(2):420-428. Schebb NH, Inceoglu B, Rose T, Wagner K, Hammock BD, Schebb NH, Inceoglu B, Rose T, Wagner K, Hammock BD. PMID: 21660124; PMCID: PMC3110015.
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    383. Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation. Circ Res. 2011 Feb 04; 108(3):324-34. Charles RL, Burgoyne JR, Mayr M, Weldon SM, Hubner N, Dong H, Morisseau C, Hammock BD, Landar A, Eaton P, Charles RL, Burgoyne JR, Mayr M, Weldon SM, Hubner N, Dong H, Morisseau C, Hammock BD, Landar A, Eaton P. PMID: 21164107; PMCID: PMC3259859.
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    384. 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. Bioorg Med Chem Lett. 2011 Feb 01; 21(3):983-8. Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R, Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R. PMID: 21211973; PMCID: PMC3529200.
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    385. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Anal Chem. 2011 Jan 01; 83(1):246-53. Kim HJ, McCoy M, Gee SJ, González-Sapienza GG, Hammock BD, Kim HJ, McCoy M, Gee SJ, González-Sapienza GG, Hammock BD. PMID: 21141939; PMCID: PMC3031424.
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    386. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. J Agric Food Chem. 2011 Apr 13; 59(7):2792-802. Ahn KC, Kim HJ, McCoy MR, Gee SJ, Hammock BD, Ahn KC, Kim HJ, McCoy MR, Gee SJ, Hammock BD. PMID: 21105656; PMCID: PMC3070843.
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    387. Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties. J Med Chem. 2010 Dec 09; 53(23):8376-86. Huang SX, Li HY, Liu JY, Morisseau C, Hammock BD, Long YQ, Huang SX, Li HY, Liu JY, Morisseau C, Hammock BD, Long YQ. PMID: 21070033; PMCID: PMC3070159.
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    388. Epoxygenated fatty acids and soluble epoxide hydrolase inhibition: novel mediators of pain reduction. J Agric Food Chem. 2011 Apr 13; 59(7):2816-24. Wagner K, Inceoglu B, Gill SS, Hammock BD, Wagner K, Inceoglu B, Gill SS, Hammock BD. PMID: 20958046; PMCID: PMC3483885.
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    389. 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain. J Med Chem. 2010 Oct 14; 53(19):7067-75. Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD, Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. PMID: 20812725; PMCID: PMC3285450.
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    390. DNA methylation of the promoter of soluble epoxide hydrolase silences its expression by an SP-1-dependent mechanism. Biochim Biophys Acta. 2010 Sep; 1799(9):659-67. Zhang D, Ai D, Tanaka H, Hammock BD, Zhu Y, Zhang D, Ai D, Tanaka H, Hammock BD, Zhu Y. PMID: 20888937.
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    391. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proc Natl Acad Sci U S A. 2010 Sep 28; 107(39):17017-22. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Liu JY, Li N, Yang J, Li N, Qiu H, Ai D, Chiamvimonvat N, Zhu Y, Hammock BD. PMID: 20837537; PMCID: PMC2947894.
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    392. Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease. PLoS One. 2010 Aug 04; 5(8):e11979. Jung O, Jansen F, Mieth A, Barbosa-Sicard E, Pliquett RU, Babelova A, Morisseau C, Hwang SH, Tsai C, Hammock BD, Schaefer L, Geisslinger G, Amann K, Brandes RP, Jung O, Jansen F, Mieth A, Barbosa-Sicard E, Pliquett RU, Babelova A, Morisseau C, Hwang SH, Tsai C, Hammock BD, Schaefer L, Geisslinger G, Amann K, Brandes RP. PMID: 20694143; PMCID: PMC2915917.
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    393. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res. 2010 Dec; 51(12):3481-90. Morisseau C, Inceoglu B, Schmelzer K, Tsai HJ, Jinks SL, Hegedus CM, Hammock BD, Morisseau C, Inceoglu B, Schmelzer K, Tsai HJ, Jinks SL, Hegedus CM, Hammock BD. PMID: 20664072; PMCID: PMC2975720.
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    394. Epoxyeicosatrienoic acids and soluble epoxide hydrolase: potential therapeutic targets for inflammation and its induced carcinogenesis. Am J Transl Res. 2010 Jul 22; 2(4):447-57. Norwood S, Liao J, Hammock BD, Yang GY, Norwood S, Liao J, Hammock BD, Yang GY. PMID: 20733953; PMCID: PMC2923867.
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    395. Juvenile hormone esterase: biochemistry and structure. J Pestic Sci. 2010 Aug 31; 35(3):265-274. Kamita SG, Hammock BD, Kamita SG, Hammock BD. PMID: 23543805; PMCID: PMC3611591.
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    396. Function of phenylalanine 259 and threonine 314 within the substrate binding pocket of the juvenile hormone esterase of Manduca sexta. Biochemistry. 2010 May 04; 49(17):3733-42. Kamita SG, Wogulis MD, Law CS, Morisseau C, Tanaka H, Huang H, Wilson DK, Hammock BD, Kamita SG, Wogulis MD, Law CS, Morisseau C, Tanaka H, Huang H, Wilson DK, Hammock BD. PMID: 20307057; PMCID: PMC3570046.
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    397. Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. J Pharmacol Exp Ther. 2010 Aug; 334(2):430-8. Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH, Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH. PMID: 20439437; PMCID: PMC2913776.
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    398. Soluble epoxide hydrolase in atherosclerosis. Curr Atheroscler Rep. 2010 May; 12(3):174-83. Wang YX, Ulu A, Zhang LN, Hammock B, Wang YX, Ulu A, Zhang LN, Hammock B. PMID: 20425256; PMCID: PMC2857794.
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    399. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. Eur J Pharm Sci. 2010 Jun 14; 40(3):222-38. Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD, Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD. PMID: 20359531; PMCID: PMC3285443.
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    400. Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice. Arterioscler Thromb Vasc Biol. 2010 May; 30(5):909-14. Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP, Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. PMID: 20224052; PMCID: PMC2919323.
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    401. Mutation of bacterium Vibrio gazogenes for selective preparation of colorants. Biotechnol Prog. 2010 Mar-Apr; 26(2):352-60. Alihosseini F, Lango J, Ju KS, Hammock BD, Sun G, Alihosseini F, Lango J, Ju KS, Hammock BD, Sun G. PMID: 19902486; PMCID: PMC2864118.
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    402. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. Free Radic Biol Med. 2010 May 15; 48(10):1311-20. Kubala L, Schmelzer KR, Klinke A, Kolarova H, Baldus S, Hammock BD, Eiserich JP, Kubala L, Schmelzer KR, Klinke A, Kolarova H, Baldus S, Hammock BD, Eiserich JP. PMID: 20156554; PMCID: PMC2856720.
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    403. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Anal Biochem. 2010 Jun 01; 401(1):38-46. Kim HJ, Rossotti MA, Ahn KC, González-Sapienza GG, Gee SJ, Musker R, Hammock BD, Kim HJ, Rossotti MA, Ahn KC, González-Sapienza GG, Gee SJ, Musker R, Hammock BD. PMID: 20152791; PMCID: PMC2861364.
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    404. Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor. J Bacteriol. 2010 Apr; 192(7):1785-95. Bahl CD, Morisseau C, Bomberger JM, Stanton BA, Hammock BD, O'Toole GA, Madden DR, Bahl CD, Morisseau C, Bomberger JM, Stanton BA, Hammock BD, O'Toole GA, Madden DR. PMID: 20118260; PMCID: PMC2838060.
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    405. Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations. J Nutr. 2010 Mar; 140(3):542-50. Hall LM, Kimlin MG, Aronov PA, Hammock BD, Slusser JR, Woodhouse LR, Stephensen CB, Hall LM, Kimlin MG, Aronov PA, Hammock BD, Slusser JR, Woodhouse LR, Stephensen CB. PMID: 20053937; PMCID: PMC2821886.
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    406. Endogenous Levels of Five Fatty Acid Metabolites in Exhaled Breath Condensate to Monitor Asthma by High-Performance Liquid Chromatography: Electrospray Tandem Mass Spectrometry. IEEE Sens J. 2010 Jan 01; 10(1):123-130. Nording ML, Yang J, Hegedus CM, Bhushan A, Kenyon NJ, Davis CE, Hammock BD, Nording ML, Yang J, Hegedus CM, Bhushan A, Kenyon NJ, Davis CE, Hammock BD. PMID: 21103452; PMCID: PMC2981865.
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    407. Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition. Cardiovasc Res. 2010 Jan 01; 85(1):232-40. Keserü B, Barbosa-Sicard E, Schermuly RT, Tanaka H, Hammock BD, Weissmann N, Fisslthaler B, Fleming I, Keserü B, Barbosa-Sicard E, Schermuly RT, Tanaka H, Hammock BD, Weissmann N, Fisslthaler B, Fleming I. PMID: 19679679; PMCID: PMC2860707.
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    408. Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury. J Cardiovasc Pharmacol. 2010 Jan; 55(1):67-73. Chaudhary KR, Abukhashim M, Hwang SH, Hammock BD, Seubert JM, Chaudhary KR, Abukhashim M, Hwang SH, Hammock BD, Seubert JM. PMID: 19834332; PMCID: PMC2824072.
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    409. Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. Biochem Pharmacol. 2010 Mar 15; 79(6):880-7. Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD, Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. PMID: 19896470; PMCID: PMC3285377.
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    410. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environ Sci Technol. 2009 Oct 15; 43(20):7784-90. Ahn KC, Gee SJ, Tsai HJ, Bennett D, Nishioka MG, Blum A, Fishman E, Hammock BD, Ahn KC, Gee SJ, Tsai HJ, Bennett D, Nishioka MG, Blum A, Fishman E, Hammock BD. PMID: 19921894; PMCID: PMC3528349.
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    411. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov. 2009 Oct; 8(10):794-805. Imig JD, Hammock BD, Imig JD, Hammock BD. PMID: 19794443; PMCID: PMC3021468.
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    412. Quantitative profiling method for oxylipin metabolome by liquid chromatography electrospray ionization tandem mass spectrometry. Anal Chem. 2009 Oct 01; 81(19):8085-93. Yang J, Schmelzer K, Georgi K, Hammock BD, Yang J, Schmelzer K, Georgi K, Hammock BD. PMID: 19715299; PMCID: PMC3290520.
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    413. Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries. J Biol Chem. 2009 Nov 06; 284(45):31280-90. Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB, Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB. PMID: 19737933; PMCID: PMC2781526.
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    414. Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase. Curr Pharm Biotechnol. 2009 Sep; 10(6):589-99. Matveeva EG, Morisseau C, Goodrow MH, Mullin C, Hammock BD, Matveeva EG, Morisseau C, Goodrow MH, Mullin C, Hammock BD. PMID: 19619123; PMCID: PMC2861369.
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    415. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. J Mol Cell Cardiol. 2009 Dec; 47(6):835-45. Li N, Liu JY, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N, Li N, Liu JY, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. PMID: 19716829; PMCID: PMC3290524.
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    416. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition. J Med Chem. 2009 Aug 27; 52(16):5069-75. Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi XY, Goldman DH, Morisseau C, Hammock BD, Campbell WB, Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi XY, Goldman DH, Morisseau C, Hammock BD, Campbell WB. PMID: 19653681; PMCID: PMC2888647.
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    417. Inhibition of the soluble epoxide hydrolase by tyrosine nitration. J Biol Chem. 2009 Oct 09; 284(41):28156-28163. Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I, Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I. PMID: 19704161; PMCID: PMC2788866.
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    418. Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. Mol Cancer Ther. 2009 Aug; 8(8):2193-203. Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH, Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH. PMID: 19671760; PMCID: PMC2728155.
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    419. Frataxin deficiency induces Schwann cell inflammation and death. Biochim Biophys Acta. 2009 Nov; 1792(11):1052-61. Lu C, Schoenfeld R, Shan Y, Tsai HJ, Hammock B, Cortopassi G, Lu C, Schoenfeld R, Shan Y, Tsai HJ, Hammock B, Cortopassi G. PMID: 19679182; PMCID: PMC3563672.
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    420. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect. 2009 Dec; 117(12):1867-72. Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD, Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. PMID: 20049205; PMCID: PMC2799460.
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    421. Immunochemical screening of pesticides (simazine and cypermethrin) in orange oil. J Agric Food Chem. 2009 Jul 08; 57(13):5673-9. Nichkova M, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD, Nichkova M, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD. PMID: 19526986; PMCID: PMC3033343.
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    422. Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension. Am J Physiol Renal Physiol. 2009 Sep; 297(3):F740-8. Manhiani M, Quigley JE, Knight SF, Tasoobshirazi S, Moore T, Brands MW, Hammock BD, Imig JD, Manhiani M, Quigley JE, Knight SF, Tasoobshirazi S, Moore T, Brands MW, Hammock BD, Imig JD. PMID: 19553349; PMCID: PMC2739707.
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    423. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E375-83. Luria A, Morisseau C, Tsai HJ, Yang J, Inceoglu B, De Taeye B, Watkins SM, Wiest MM, German JB, Hammock BD, Luria A, Morisseau C, Tsai HJ, Yang J, Inceoglu B, De Taeye B, Watkins SM, Wiest MM, German JB, Hammock BD. PMID: 19458064; PMCID: PMC2724109.
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    424. Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. Am J Pathol. 2009 Jun; 174(6):2086-95. Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD, Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD. PMID: 19435785; PMCID: PMC2684174.
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    425. Novel and highly sensitive fluorescent assay for leucine aminopeptidases. Anal Biochem. 2009 Aug 01; 391(1):11-6. Huang H, Tanaka H, Hammock BD, Morisseau C, Huang H, Tanaka H, Hammock BD, Morisseau C. PMID: 19433052; PMCID: PMC2748848.
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    426. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. J Magn Magn Mater. 2009 May 01; 321(10):1368-1371. Ma Z, Dosev D, Nichkova M, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM, Ma Z, Dosev D, Nichkova M, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM. PMID: 20336173; PMCID: PMC2844650.
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    427. Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats. J Hypertens. 2009 Feb; 27(2):322-31. Revermann M, Barbosa-Sicard E, Dony E, Schermuly RT, Morisseau C, Geisslinger G, Fleming I, Hammock BD, Brandes RP, Revermann M, Barbosa-Sicard E, Dony E, Schermuly RT, Morisseau C, Geisslinger G, Fleming I, Hammock BD, Brandes RP. PMID: 19226702; PMCID: PMC2863009.
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    428. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorg Med Chem Lett. 2009 Mar 15; 19(6):1784-9. Kasagami T, Kim IH, Tsai HJ, Nishi K, Hammock BD, Morisseau C, Kasagami T, Kim IH, Tsai HJ, Nishi K, Hammock BD, Morisseau C. PMID: 19216074; PMCID: PMC2900318.
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    429. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. Br J Pharmacol. 2009 Jan; 156(2):284-96. Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD, Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. PMID: 19154430; PMCID: PMC2697843.
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    430. Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):564-9. Ai D, Pang W, Li N, Xu M, Jones PD, Yang J, Zhang Y, Chiamvimonvat N, Shyy JY, Hammock BD, Zhu Y, Ai D, Pang W, Li N, Xu M, Jones PD, Yang J, Zhang Y, Chiamvimonvat N, Shyy JY, Hammock BD, Zhu Y. PMID: 19126686; PMCID: PMC2626743.
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    431. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond). 2009 Jan; 116(1):61-70. Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD, Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD. PMID: 18459944; PMCID: PMC2590620.
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    432. Synthesis and bio-functionalization of multifunctional magnetic Fe(3)O(4)@Y(2)O(3):Eu nanocomposites. J Mater Chem. 2009 Jan 01; 19(27):4695-4700. Ma ZY, Dosev D, Nichkova M, Gee SJ, Hammock BD, Kennedy IM, Ma ZY, Dosev D, Nichkova M, Gee SJ, Hammock BD, Kennedy IM. PMID: 20357905; PMCID: PMC2847302.
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    433. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Anal Biochem. 2009 Mar 01; 386(1):45-52. Kim HJ, Ahn KC, González-Techera A, González-Sapienza GG, Gee SJ, Hammock BD, Kim HJ, Ahn KC, González-Techera A, González-Sapienza GG, Gee SJ, Hammock BD. PMID: 19101498; PMCID: PMC2863013.
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    434. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18901-6. Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD, Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD. PMID: 19028872; PMCID: PMC2596245.
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    435. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. J Biol Chem. 2008 Dec 26; 283(52):36592-8. EnayetAllah AE, Luria A, Luo B, Tsai HJ, Sura P, Hammock BD, Grant DF, EnayetAllah AE, Luria A, Luo B, Tsai HJ, Sura P, Hammock BD, Grant DF. PMID: 18974052; PMCID: PMC2605982.
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    436. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. J Cardiovasc Pharmacol. 2008 Oct; 52(4):314-23. Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH, Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. PMID: 18791465; PMCID: PMC2637359.
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    437. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. J Pharmacol Exp Ther. 2008 Dec; 327(3):707-15. Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL, Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL. PMID: 18815352; PMCID: PMC2761654.
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    438. Discovery of potent non-urea inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett. 2009 Apr 15; 19(8):2354-9. Xie Y, Liu Y, Gong G, Smith DH, Yan F, Rinderspacher A, Feng Y, Zhu Z, Li X, Deng SX, Branden L, Vidovic D, Chung C, Schürer S, Morisseau C, Hammock BD, Landry DW, Xie Y, Liu Y, Gong G, Smith DH, Yan F, Rinderspacher A, Feng Y, Zhu Z, Li X, Deng SX, Branden L, Vidovic D, Chung C, Schürer S, Morisseau C, Hammock BD, Landry DW. PMID: 19303288; PMCID: PMC2738751.
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    439. Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence. DNA Cell Biol. 2008 Sep; 27(9):467-77. Harris TR, Aronov PA, Hammock BD, Harris TR, Aronov PA, Hammock BD. PMID: 18554159; PMCID: PMC2858585.