Bruce D Hammock

Title(s)Professor, Entomology
SchoolUniversity of California, Davis
Address90 Briggs Hall
CA 95616
Phone530-752-7519
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. Pflugers Arch. 2022 Jun 01. Naeem Z, Zukunft S, Günther S, Liebner S, Weigert A, Hammock BD, Frömel T, Fleming I. PMID: 35648219.
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    2. Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary tracer. Anal Methods. 2022 Apr 28. Singh N, Li D, McReynolds CB, Morisseau C, Hammock BD. PMID: 35481804.
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    3. Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor. PLoS One. 2022; 17(4):e0266608. Zhang C, Li W, Li X, Wan D, Mack S, Zhang J, Wagner K, Wang C, Tan B, Chen J, Wu CW, Tsuji K, Takeuchi M, Chen Z, Hammock BD, Pinkerton KE, Yang J. PMID: 35443010; PMCID: PMC9020733.
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    4. sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury. Proc Natl Acad Sci U S A. 2022 Mar 29; 119(13):e2120691119. Bergmann CB, McReynolds CB, Wan D, Singh N, Goetzman H, Caldwell CC, Supp DM, Hammock BD. PMID: 35312372; PMCID: PMC9060469.
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    5. Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint. Inflammopharmacology. 2022 Jun; 30(3):981-990. Abdalla HB, Napimoga MH, Teixeira JM, Trindade-da-Silva CA, Pieroni VL, Dos Santos Araújo FSM, Hammock BD, Clemente-Napimoga JT. PMID: 35303234.
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    6. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022 03 24; 65(6):4909-4925. Codony S, Pont C, Griñán-Ferré C, Di Pede-Mattatelli A, Calvó-Tusell C, Feixas F, Osuna S, Jarné-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Pérez B, Bartra C, Sanfeliu C, Juárez-Jiménez J, Morisseau C, Hammock BD, Pallàs M, Vázquez S, Muñoz-Torrero D. PMID: 35271276; PMCID: PMC8958510.
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    7. Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain. Arthritis Rheumatol. 2022 04; 74(4):623-633. Gowler PRW, Turnbull J, Shahtaheri M, Gohir S, Kelly T, McReynolds C, Yang J, Jha RR, Fernandes GS, Zhang W, Doherty M, Walsh DA, Hammock BD, Valdes AM, Barrett DA, Chapman V. PMID: 34672113; PMCID: PMC8957539.
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    8. Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model. Proc Natl Acad Sci U S A. 2022 03 01; 119(9). Sun CP, Zhou JJ, Yu ZL, Huo XK, Zhang J, Morisseau C, Hammock BD, Ma XC. PMID: 35217618; PMCID: PMC8892522.
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    9. Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysis. Mycotoxin Res. 2022 Feb; 38(1):51-60. Pang Q, Chen Y, Mukhtar H, Xiong J, Wang X, Xu T, Hammock BD, Wang J. PMID: 35023020; PMCID: PMC8754551.
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    10. "Ready-to-use" immunosensor for the detection of small molecules with fast readout. Biosens Bioelectron. 2022 Apr 01; 201:113968. Ding Y, Cui P, Chen H, Li J, Huang L, González-Sapienza G, Hammock BD, Wang M, Hua X. PMID: 35007993; PMCID: PMC8863114.
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    11. A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry. Molecules. 2022 Jan 03; 27(1). Wan D, Morisseau C, Hammock BD, Yang J. PMID: 35011515; PMCID: PMC8747065.
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    12. COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl 4 -Induced Liver Fibrosis and Portal Hypertension. Front Med (Lausanne). 2021; 8:761517. Zhao Z, Zhang C, Lin J, Zheng L, Li H, Qi X, Huo H, Lou X, Hammock BD, Hwang SH, Bao Y, Luo M. PMID: 35004731; PMCID: PMC8734593.
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    13. Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. Front Pharmacol. 2021; 12:778470. Wagner KM, Yang J, Morisseau C, Hammock BD. PMID: 34975481; PMCID: PMC8719166.
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    14. 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity. Pharmaceuticals (Basel). 2021 Dec 17; 14(12). Martín-López J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vázquez S. PMID: 34959721; PMCID: PMC8703317.
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    15. Author Correction: Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2021 Dec 14; 11(1):24259. Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 34907191; PMCID: PMC8671385.
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    16. Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity. Front Pharmacol. 2021; 12:744776. Jankiewicz WK, Barnett SD, Stavniichuk A, Hwang SH, Hammock BD, Belayet JB, Khan AH, Imig JD. PMID: 34955823; PMCID: PMC8695932.
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    17. New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. Chem Res Toxicol. 2021 12 20; 34(12):2579-2591. Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD. PMID: 34817988; PMCID: PMC8853703.
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    18. Soluble epoxide hydrolase inhibitor can protect the femoral head against tobacco smoke exposure-induced osteonecrosis in spontaneously hypertensive rats. Toxicology. 2022 01 15; 465:153045. Xu J, Qiu X, Yu G, Ly M, Yang J, Silva RM, Zhang X, Yu M, Wang Y, Hammock B, Pinkerton KE, Zhao D. PMID: 34801612.
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    19. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021 12 01; 51:116507. Wilt S, Kodani S, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 34794001; PMCID: PMC8900675.
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    20. Eicosanoid regulation of debris-stimulated metastasis. Proc Natl Acad Sci U S A. 2021 10 12; 118(41). Deng J, Yang H, Haak VM, Yang J, Kipper FC, Barksdale C, Hwang SH, Gartung A, Bielenberg DR, Subbian S, Ho KK, Ye X, Fan D, Sun Y, Hammock BD, Panigrahy D. PMID: 34607951; PMCID: PMC8521662.
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    21. Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for sensitive detection of 1-naphthol for the exposure assessment of pesticide carbaryl. J Hazard Mater. 2022 02 15; 424(Pt C):127411. Chen ZJ, Wu HL, Shen YD, Wang H, Zhang YF, Hammock B, Li ZF, Luo L, Lei HT, Xu ZL. PMID: 34629198; PMCID: PMC8877597.
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    22. Smartphone-Based Dual-Channel Immunochromatographic Test Strip with Polymer Quantum Dot Labels for Simultaneous Detection of Cypermethrin and 3-Phenoxybenzoic Acid. Anal Chem. 2021 10 12; 93(40):13658-13666. Zhao Y, Ruan X, Song Y, Smith JN, Vasylieva N, Hammock BD, Lin Y, Du D. PMID: 34591463; PMCID: PMC8655817.
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    23. Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain. Acta Pharm Sin B. 2022 Mar; 12(3):1377-1389. Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G. PMID: 35530144; PMCID: PMC9072249.
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    24. Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction. Cardiovasc Drugs Ther. 2021 Sep 09. Thai PN, Ren L, Xu W, Overton J, Timofeyev V, Nader CE, Haddad M, Yang J, Gomes AV, Hammock BD, Chiamvimonvat N, Sirish P. PMID: 34499283; PMCID: PMC8904649.
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    25. Enhanced Bio-Barcode Immunoassay Using Droplet Digital PCR for Multiplex Detection of Organophosphate Pesticides. J Agric Food Chem. 2021 Sep 22; 69(37):11131-11141. Cui X, Abd El-Aty AM, Zhang C, Xu L, Liu H, Jia H, Wang Y, Cao Z, Salvador JP, She Y, Jin F, Wang J, Jin M, Hammock BD. PMID: 34494438.
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    26. Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure. Clin Psychopharmacol Neurosci. 2021 Aug 31; 19(3):554-558. Pu Y, Ma L, Shan J, Wan X, Hammock BD, Hashimoto K. PMID: 34294625; PMCID: PMC8316667.
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    27. Pharmacokinetics, Metabolite Measurement, and Biomarker Identification of Dermal Exposure to Permethrin Using Accelerator Mass Spectrometry. Toxicol Sci. 2021 08 30; 183(1):49-59. Buchholz BA, Ahn KC, Huang H, Gee SJ, Stewart BJ, Ognibene TJ, Hammock BD. PMID: 34460930; PMCID: PMC8404990.
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    28. Sortase-Mediated Phage Decoration for Analytical Applications. Anal Chem. 2021 08 31; 93(34):11800-11808. Ding Y, Chen H, Li J, Huang L, Song G, Li Z, Hua X, Gonzalez-Sapienza G, Hammock BD, Wang M. PMID: 34415158; PMCID: PMC8853704.
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    29. Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development. Molecules. 2021 Aug 19; 26(16). McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. PMID: 34443621; PMCID: PMC8399023.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    30. Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway. Food Chem Toxicol. 2021 Oct; 156:112516. Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC. PMID: 34411643; PMCID: PMC8889936.
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    31. TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function. Sci Rep. 2021 08 16; 11(1):16555. Bergmann CB, Hammock BD, Wan D, Gogolla F, Goetzman H, Caldwell CC, Supp DM. PMID: 34400718; PMCID: PMC8368302.
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    32. Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. Br J Pharmacol. 2021 11; 178(22):4468-4484. Khan MAH, Hwang SH, Barnett SD, Stavniichuk A, Jankiewicz WK, Hammock BD, Imig JD. PMID: 34255857; PMCID: PMC8863090.
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    33. Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detection of ochratoxin A. J Hazard Mater. 2022 01 15; 422:126838. Su B, Zhang Z, Sun Z, Tang Z, Xie X, Chen Q, Cao H, Yu X, Xu Y, Liu X, Hammock BD. PMID: 34411960; PMCID: PMC8889937.
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    34. EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. Elife. 2021 08 03; 10. Gautheron J, Morisseau C, Chung WK, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Fève B, Vigouroux C, Andreelli F, Jeru I. PMID: 34342583; PMCID: PMC8331186.
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    35. Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice. Int J Mol Sci. 2021 Jul 31; 22(15). Yang Y, Xu X, Wu H, Yang J, Chen J, Morisseau C, Hammock BD, Bettaieb A, Zhao L. PMID: 34361032; PMCID: PMC8347952.
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    36. Development of a direct competitive enzyme-linked immunosorbent assay for quantitation of sodium saccharin residue in food. J Food Sci. 2021 Aug; 86(8):3720-3729. Zhao Y, Wang M, Zhang M, Yang X, Li Z, Vasylieva N, Tan G, Wang B, Hammock BD. PMID: 34309034.
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    37. Immune response dynamics in COVID-19 patients to SARS-CoV-2 and other human coronaviruses. PLoS One. 2021; 16(7):e0254367. Ravindran R, McReynolds C, Yang J, Hammock BD, Ikram A, Ali A, Bashir A, Zohra T, Chang WLW, Hartigan-O'Connor DJ, Rashidi HH, Khan IH. PMID: 34242356; PMCID: PMC8270414.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCTClinical Trials
    38. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome. Drug Metab Dispos. 2021 09; 49(9):810-821. Fang Y, Johnson H, Anderl JL, Muchamuel T, McMinn D, Morisseau C, Hammock BD, Kirk C, Wang J. PMID: 34234005.
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    39. Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis. Eur J Med Chem. 2021 Nov 05; 223:113678. Du F, Sun W, Morisseau C, Hammock BD, Bao X, Liu Q, Wang C, Zhang T, Yang H, Zhou J, Xiao W, Liu Z, Chen G. PMID: 34218083; PMCID: PMC8877601.
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    40. Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve. J Affect Disord. 2021 09 01; 292:565-573. Wang S, Ishima T, Qu Y, Shan J, Chang L, Wei Y, Zhang J, Pu Y, Fujita Y, Tan Y, Wang X, Ma L, Wan X, Hammock BD, Hashimoto K. PMID: 34147969; PMCID: PMC8282729.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop. Nutrients. 2021 May 31; 13(6). Baek SJ, Hammock BD, Hwang IK, Li Q, Moustaid-Moussa N, Park Y, Safe S, Suh N, Yi SS, Zeldin DC, Zhong Q, Bradbury JA, Edin ML, Graves JP, Jung HY, Jung YH, Kim MB, Kim W, Lee J, Li H, Moon JS, Yoo ID, Yue Y, Lee JY, Han HJ. PMID: 34072678; PMCID: PMC8227583.
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    42. Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss. Free Radic Biol Med. 2021 08 20; 172:48-57. Koike S, Hsu MF, Bettaieb A, Chu B, Matsumoto N, Morisseau C, Havel PJ, Huising MO, Hammock BD, Haj FG. PMID: 34038767.
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    43. Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. Antioxidants (Basel). 2021 May 20; 10(5). Mavangira V, Kuhn MJ, Abuelo A, Morisseau C, Hammock BD, Sordillo LM. PMID: 34065244; PMCID: PMC8161397.
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    44. A sensitive bio-barcode immunoassay based on bimetallic Au@Pt nanozyme for detection of organophosphate pesticides in various agro-products. Food Chem. 2021 Nov 15; 362:130118. Chen G, Liu G, Jia H, Cui X, Wang Y, Li D, Zheng W, She Y, Xu D, Huang X, Abd El-Aty AM, Sun J, Liu H, Zou Y, Wang J, Jin M, Hammock BD. PMID: 34082296.
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    45. Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. Int J Mol Sci. 2021 May 08; 22(9). Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD. PMID: 34066758; PMCID: PMC8125816.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    46. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. J Med Chem. 2021 05 13; 64(9):5429-5446. Codony S, Calvó-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Pérez C, Rodríguez-Franco MI, Pizarro-Delgado J, Corpas R, Griñán-Ferré C, Pallàs M, Sanfeliu C, Vázquez-Carrera M, Hammock BD, Feixas F, Vázquez S. PMID: 33945278; PMCID: PMC8634379.
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    47. A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis. Int J Mol Sci. 2021 Apr 28; 22(9). Jonnalagadda D, Wan D, Chun J, Hammock BD, Kihara Y. PMID: 33925035; PMCID: PMC8125305.
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    48. Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit juices with a specific camel polyclonal antibody. Anal Methods. 2021 04 22; 13(15):1795-1802. Wang F, Wan DB, Shen YD, Tian YX, Xiao ZL, Xu ZL, Yang JY, Sun YM, Hammock BD, Wang H. PMID: 33885655.
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    49. Enhanced Non-Toxic Immunodetection of Alternaria Mycotoxin Tenuazonic Acid Based on Ferritin-Displayed Anti-Idiotypic Nanobody-Nanoluciferase Multimers. J Agric Food Chem. 2021 Apr 28; 69(16):4911-4917. Wang F, Li ZF, Wan DB, Vasylieva N, Shen YD, Xu ZL, Yang JY, Gettemans J, Wang H, Hammock BD, Sun YM. PMID: 33870684.
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    50. Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections. Front Physiol. 2021; 12:663869. McReynolds CB, Cortes-Puch I, Ravindran R, Khan IH, Hammock BG, Shih PB, Hammock BD, Yang J. PMID: 33868029; PMCID: PMC8047414.
      View in: PubMed   Mentions: 3  
    51. Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. Sci Rep. 2021 03 29; 11(1):7042. Tiwari S, Yang J, Morisseau C, Durbin-Johnson B, Hammock BD, Gomes AV. PMID: 33782432; PMCID: PMC8007717.
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    52. Development of nanobody-based flow-through dot ELISA and lateral-flow immunoassay for rapid detection of 3-phenoxybenzoic acid. Anal Methods. 2021 04 14; 13(14):1757-1765. Zhang C, Wu X, Li D, Hu J, Wan D, Zhang Z, Hammock BD. PMID: 33861243; PMCID: PMC8442667.
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    53. Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain. ACS Omega. 2021 Mar 16; 6(10):7165-7174. Singh N, Barnych B, Wagner KM, Wan D, Morisseau C, Hammock BD. PMID: 33748630; PMCID: PMC7970556.
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    54. Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence Enzyme Immunoassay for trace Glypican-3 in Serum. Sens Actuators B Chem. 2021 Jun 01; 336. Yu S, Li Z, Li J, Zhao S, Wu S, Liu H, Bi X, Li D, Dong J, Duan S, Hammock BD. PMID: 35250176; PMCID: PMC8896807.
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    55. Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor immunotherapy. Signal Transduct Target Ther. 2021 02 25; 6(1):80. Mo F, Duan S, Jiang X, Yang X, Hou X, Shi W, Carlos CJJ, Liu A, Yin S, Wang W, Yao H, Yu Z, Tang Z, Xie S, Ding Z, Zhao X, Hammock BD, Lu X. PMID: 33627635; PMCID: PMC7904846.
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    56. Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chlorantraniliprole in soil and the vegetable bok choy. Anal Bioanal Chem. 2021 Apr; 413(9):2503-2511. Xu B, Wang K, Vasylieva N, Zhou H, Xue X, Wang B, Li QX, Hammock BD, Xu T. PMID: 33580830; PMCID: PMC8422987.
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    57. Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. Int J Mol Sci. 2021 Feb 08; 22(4). Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM. PMID: 33567578; PMCID: PMC7915306.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    58. Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative. J Med Chem. 2021 02 25; 64(4):1856-1872. Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. PMID: 33550801; PMCID: PMC7917437.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    59. Fusion expression of nanobodies specific for the insecticide fipronil on magnetosomes in Magnetospirillum gryphiswaldense MSR-1. J Nanobiotechnology. 2021 Jan 19; 19(1):27. Wu S, Ma F, He J, Li QX, Hammock BD, Tian J, Xu T. PMID: 33468141; PMCID: PMC7816308.
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    60. Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence. J Pain Res. 2021; 14:61-72. Wang Y, Wagner KM, Morisseau C, Hammock BD. PMID: 33488116; PMCID: PMC7814236.
      View in: PubMed   Mentions: 1  
    61. Reply to Reeves and Dunn: Risk for autism in offspring after maternal glyphosate exposure. Proc Natl Acad Sci U S A. 2021 01 12; 118(2). Hashimoto K, Hammock BD. PMID: 33443192; PMCID: PMC7812790.
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    62. A visual bio-barcode immunoassay for sensitive detection of triazophos based on biochip silver staining signal amplification. Food Chem. 2021 Jun 15; 347:129024. Wang Y, Du P, Abd El-Aty AM, Chen G, Jia H, Cui X, Oz E, Zhang Y, Zhang X, Qin G, Yan F, Wang J, Jin M, Hammock BD. PMID: 33461115.
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    63. Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. J Med Chem. 2021 01 14; 64(1):184-215. Sun CP, Zhang XY, Morisseau C, Hwang SH, Zhang ZJ, Hammock BD, Ma XC. PMID: 33369424; PMCID: PMC7942193.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    64. Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy. J Mol Cell Cardiol. 2021 05; 154:80-91. Wang L, Zhao D, Tang L, Li H, Liu Z, Gao J, Edin ML, Zhang H, Zhang K, Chen J, Zhu X, Wang D, Zeldin DC, Hammock BD, Wang J, Huang H. PMID: 33378686; PMCID: PMC8068623.
      View in: PubMed   Mentions: 1     Fields:    
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    66. An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. Sci Transl Med. 2020 12 09; 12(573). Ghosh A, Comerota MM, Wan D, Chen F, Propson NE, Hwang SH, Hammock BD, Zheng H. PMID: 33298560; PMCID: PMC7784555.
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    67. EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua. Sci Rep. 2020 11 19; 10(1):20183. Vatanparast M, Ahmed S, Lee DH, Hwang SH, Hammock B, Kim Y. PMID: 33214688; PMCID: PMC7677322.
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    68. ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizing Enzymes Involved. Nutrients. 2020 Oct 28; 12(11). Tu M, Wang W, Zhang G, Hammock BD. PMID: 33126566; PMCID: PMC7693568.
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    69. Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABAA Receptor. Mol Pharmacol. 2021 01; 99(1):78-91. Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. PMID: 33109687; PMCID: PMC7746976.
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    70. Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors. J Clin Pharmacol. 2021 04; 61(4):531-537. An G, Lee KSS, Yang J, Hammock BD. PMID: 33078430; PMCID: PMC7969377.
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    71. Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 2021; 11(3):815-830. Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG. PMID: 33068774; PMCID: PMC7851189.
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    72. Development of a sensitive non-competitive immunoassay via immunocomplex binding peptide for the determination of ethyl carbamate in wine samples. J Hazard Mater. 2021 03 15; 406:124288. Fu HJ, Chen ZJ, Wang H, Luo L, Wang Y, Huang RM, Xu ZL, Hammock B. PMID: 33525128; PMCID: PMC8893042.
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    74. Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. Sci Rep. 2020 09 29; 10(1):16032. Knuth MM, Mahapatra D, Jima D, Wan D, Hammock BD, Law M, Kullman SW. PMID: 32994480; PMCID: PMC7524799.
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    76. Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine. Neuropsychopharmacol Rep. 2020 12; 40(4):412-416. Wan X, Fujita Y, Chang L, Wei Y, Ma L, Wuyun G, Pu Y, Hammock BD, Hashimoto K. PMID: 32896112; PMCID: PMC7722641.
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    78. Carcinogenesis: Failure of resolution of inflammation? Pharmacol Ther. 2021 02; 218:107670. Fishbein A, Hammock BD, Serhan CN, Panigrahy D. PMID: 32891711; PMCID: PMC7470770.
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    79. Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery. Nat Chem. 2020 10; 12(10):906-913. Brighty GJ, Botham RC, Li S, Nelson L, Mortenson DE, Li G, Morisseau C, Wang H, Hammock BD, Sharpless KB, Kelly JW. PMID: 32868886; PMCID: PMC7541551.
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    80. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 11 15; 28(22):115735. Lee KSS, Ng JC, Yang J, Hwang SH, Morisseau C, Wagner K, Hammock BD. PMID: 33007552; PMCID: PMC7914304.
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    81. Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies. Bioorg Chem. 2020 10; 103:104165. Wilt S, Kodani S, Le TNH, Nguyen L, Vo N, Ly T, Rodriguez M, Hudson PK, Morisseau C, Hammock BD, Pecic S. PMID: 32891856; PMCID: PMC7723751.
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    82. Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci. 2020; 7:580. Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. PMID: 33005645; PMCID: PMC7479175.
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    84. Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its contamination in environmental water. Sci Total Environ. 2021 Jan 20; 753:141950. Li ZF, Dong JX, Vasylieva N, Cui YL, Wan DB, Hua XD, Huo JQ, Yang DC, Gee SJ, Hammock BD. PMID: 32906044; PMCID: PMC7674261.
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    85. Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. J Nutr Biochem. 2020 12; 86:108484. Hildreth K, Kodani SD, Hammock BD, Zhao L. PMID: 32827665; PMCID: PMC7606796.
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    86. Early antihypertensive treatment and ischemia-induced acute kidney injury. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F563-F570. Greite R, Derlin K, Hensen B, Thorenz A, Rong S, Chen R, Hellms S, Jang MS, Bräsen JH, Meier M, Willenberg I, Immenschuh S, Haller H, Luft FC, Panigrahy D, Hwang SH, Hammock BD, Schebb NH, Gueler F. PMID: 32799675; PMCID: PMC7642887.
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    87. Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer. Anal Chem. 2020 09 01; 92(17):11654-11663. Li D, Cui Y, Morisseau C, Wagner KM, Cho YS, Hammock BD. PMID: 32786492; PMCID: PMC7745732.
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    88. Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21576-21587. Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D. PMID: 32801214; PMCID: PMC7474612.
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    89. Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy. Stem Cells Transl Med. 2020 12; 9(12):1570-1584. Sirish P, Thai PN, Lee JH, Yang J, Zhang XD, Ren L, Li N, Timofeyev V, Lee KSS, Nader CE, Rowland DJ, Yechikov S, Ganaga S, Young N, Lieu DK, Yamoah EN, Hammock BD, Chiamvimonvat N. PMID: 32790136; PMCID: PMC7695637.
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    90. Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycotoxin by Exploitation of Nanobody and Nanobody-Nanoluciferase Fusion. Anal Chem. 2020 09 01; 92(17):11935-11942. Wang F, Li ZF, Yang YY, Wan DB, Vasylieva N, Zhang YQ, Cai J, Wang H, Shen YD, Xu ZL, Hammock BD. PMID: 32702970; PMCID: PMC7743996.
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    92. 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats. Eur Rev Med Pharmacol Sci. 2020 08; 24(15):8143-8150. Bukhari IA, Alorainey BI, Al-Motrefi AA, Mahmoud A, Campbell WB, Hammock BD. PMID: 32767352; PMCID: PMC7990106.
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    93. On-spot quantitative analysis of dicamba in field waters using a lateral flow immunochromatographic strip with smartphone imaging. Anal Bioanal Chem. 2020 Oct; 412(25):6995-7006. Qi M, Huo J, Li Z, He C, Li D, Wang Y, Vasylieva N, Zhang J, Hammock BD. PMID: 32737550; PMCID: PMC7771584.
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    96. Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for the Detection of Cyproheptadine Hydrochloride in Animal-Derived Food. Front Chem. 2020; 8:575. Li P, Yang C, Liu B, Wu Q, Wang Y, Dong S, Zhang H, Vasylieva N, Hammock BD, Zhang C. PMID: 32760698; PMCID: PMC7372008.
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    98. An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion for the Detection of Tetrabromobisphenol A in Sediment. Anal Chem. 2020 07 21; 92(14):10083-10090. Li Z, Wang Y, Vasylieva N, Wan D, Yin Z, Dong J, Hammock BD. PMID: 32559059; PMCID: PMC7780847.
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    99. Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice. J Agric Food Chem. 2020 Jul 22; 68(29):7641-7647. Xie M, Yang J, Zhang J, Sherman HL, Zhang Z, Minter LM, Hammock BD, Park Y, Zhang G. PMID: 32594738; PMCID: PMC7901524.
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    101. Monitoring of the Organophosphate Pesticide Chlorpyrifos in Vegetable Samples from Local Markets in Northern Thailand by Developed Immunoassay. Int J Environ Res Public Health. 2020 06 30; 17(13). Hongsibsong S, Prapamontol T, Xu T, Hammock BD, Wang H, Chen ZJ, Xu ZL. PMID: 32630084; PMCID: PMC7369984.
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    102. A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environmental toxin. Electroanalysis. 2020 Sep; 32(9):2056-2064. Kumar S, Vasylieva N, Singh V, Hammock B, Singh SG. PMID: 33456276; PMCID: PMC7806194.
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    105. Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11753-11759. Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. PMID: 32398374; PMCID: PMC7260984.
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    106. Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression. Sci Rep. 2020 05 12; 10(1):7843. Huerta-Yepez S, Tirado-Rodriguez A, Montecillo-Aguado MR, Yang J, Hammock BD, Hankinson O. PMID: 32398692; PMCID: PMC7217871.
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    107. Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids. Cells. 2020 04 29; 9(5). Edin ML, Lih FB, Hammock BD, Thomson S, Zeldin DC, Bishop-Bailey D. PMID: 32365470; PMCID: PMC7290345.
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    109. Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis. J Affect Disord. 2020 06 01; 270:131-134. Zhang J, Tan Y, Chang L, Hammock BD, Hashimoto K. PMID: 32339103; PMCID: PMC7243919.
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    110. Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide Hydrolase. J Pharmacol Exp Ther. 2020 07; 374(1):223-232. Wu N, Hammock BD, Lee KSS, An G. PMID: 32238455; PMCID: PMC7318792.
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    112. Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and development of an easy-to-use ELISA in urine samples. Ecotoxicol Environ Saf. 2020 Jun 15; 196:110533. Chen ZJ, Liu XX, Xiao ZL, Fu HJ, Huang YP, Huang SY, Shen YD, He F, Yang XX, Hammock B, Xu ZL. PMID: 32247241; PMCID: PMC7200204.
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    114. A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation. Theranostics. 2020; 10(11):4749-4761. Yang HH, Duan JX, Liu SK, Xiong JB, Guan XX, Zhong WJ, Sun CC, Zhang CY, Luo XQ, Zhang YF, Chen P, Hammock BD, Hwang SH, Jiang JX, Zhou Y, Guan CX. PMID: 32308747; PMCID: PMC7163435.
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    116. Single-chain variable fragment antibody-based immunochromatographic strip for rapid detection of fumonisin B1 in maize samples. Food Chem. 2020 Jul 30; 319:126546. Ren W, Xu Y, Huang Z, Li Y, Tu Z, Zou L, He Q, Fu J, Liu S, Hammock BD. PMID: 32179370.
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    118. A sensitive fluorometric bio-barcodes immunoassay for detection of triazophos residue in agricultural products and water samples by iterative cycles of DNA-RNA hybridization and dissociation of fluorophores by Ribonuclease H. Sci Total Environ. 2020 May 15; 717:137268. Zhang X, Du P, Cui X, Chen G, Wang Y, Zhang Y, Abd El-Aty AM, Hacimüftüoglu A, Wang J, He H, Jin M, Hammock B. PMID: 32084695; PMCID: PMC7938870.
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    121. An Innovative Nanobody-Based Electrochemical Immunosensor Using Decorated Nylon Nanofibers for Point-of-Care Monitoring of Human Exposure to Pyrethroid Insecticides. ACS Appl Mater Interfaces. 2020 Feb 05; 12(5):6159-6168. El-Moghazy AY, Huo J, Amaly N, Vasylieva N, Hammock BD, Sun G. PMID: 31927905; PMCID: PMC7799635.
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    124. Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatment techniques. Environ Chem. 2020; 17(1):1-5. Späth J, Nording M, Lindberg R, Brodin T, Jansson S, Yang J, Wan D, Hammock B, Fick J. PMID: 33692653; PMCID: PMC7943040.
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    125. Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation. Adv Exp Med Biol. 2020; 1274:71-99. McReynolds C, Morisseau C, Wagner K, Hammock B. PMID: 32894508; PMCID: PMC7737916.
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    128. Soluble epoxide hydrolase inhibitor mediated analgesia lacks tolerance in rat models. Brain Res. 2020 02 01; 1728:146573. Wagner KM, Atone J, Hammock BD. PMID: 31790682; PMCID: PMC6996511.
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    129. Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats. Kidney Blood Press Res. 2019; 44(6):1493-1505. Certíková Chábová V, Kujal P, Vanourková Z, Škaroupková P, Sadowski J, Kompanowska-Jezierska E, Tesar V, Hammock B, Imig J, Maxová H, Cervenka L, Vanecková I. PMID: 31770762.
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    130. Ultrasensitive and rapid detection of ochratoxin A in agro-products by a nanobody-mediated FRET-based immunosensor. J Hazard Mater. 2020 04 05; 387:121678. Tang Z, Liu X, Su B, Chen Q, Cao H, Yun Y, Xu Y, Hammock BD. PMID: 31753666; PMCID: PMC7990105.
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    131. COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence. FEBS J. 2020 04; 287(8):1666-1680. Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX. PMID: 31646730; PMCID: PMC7174142.
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    132. Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. Lipids. 2020 01; 55(1):7-22. Otoki Y, Metherel AH, Pedersen T, Yang J, Hammock BD, Bazinet RP, Newman JW, Taha AY. PMID: 31691988; PMCID: PMC7220815.
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    133. A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil samples based on a bifunctional fusion protein. Ecotoxicol Environ Saf. 2020 Jan 30; 188:109904. Fu HJ, Wang Y, Xiao ZL, Wang H, Li ZF, Shen YD, Lei HT, Sun YM, Xu ZL, Hammock B. PMID: 31704326; PMCID: PMC7198468.
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    134. Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases. Prostaglandins Other Lipid Mediat. 2020 04; 147:106385. Atone J, Wagner K, Hashimoto K, Hammock BD. PMID: 31698143; PMCID: PMC7067627.
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    135. A Nanobody Against Cytotoxic T-Lymphocyte Associated Antigen-4 Increases the Anti-Tumor Effects of Specific CD8+ T Cells. J Biomed Nanotechnol. 2019 Nov 01; 15(11):2229-2239. Tang Z, Mo F, Liu A, Duan S, Yang X, Liang L, Hou X, Yin S, Jiang X, Vasylieva N, Dong J, Barnych B, Hammock BD, Lu X. PMID: 31847937.
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    136. Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2. J Lipid Res. 2019 12; 60(12):1996-2005. Rand AA, Rajamani A, Kodani SD, Harris TR, Schlatt L, Barnych B, Passerini AG, Hammock BD. PMID: 31641036; PMCID: PMC6889709.
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    137. Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. Biomolecules. 2019 10 11; 9(10). Luo L, Wei XQ, Jia BZ, Yang JY, Shen YD, Hammock B, Dong JX, Wang H, Lei HT, Xu ZL. PMID: 31614550; PMCID: PMC6843301.
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    138. Microfluidic cap-to-dispense (μCD): a universal microfluidic-robotic interface for automated pipette-free high-precision liquid handling. Lab Chip. 2019 10 09; 19(20):3405-3415. Wang J, Deng K, Zhou C, Fang Z, Meyer C, Deshpande KU, Li Z, Mi X, Luo Q, Hammock BD, Tan C, Chen Y, Pan T. PMID: 31501848; PMCID: PMC6785371.
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    139. Investigation of the Small Size of Nanobodies for a Sensitive Fluorescence Polarization Immunoassay for Small Molecules: 3-Phenoxybenzoic Acid, an Exposure Biomarker of Pyrethroid Insecticides as a Model. J Agric Food Chem. 2019 Oct 16; 67(41):11536-11541. Wang Y, Li Z, Barnych B, Huo J, Wan D, Vasylieva N, Xu J, Li P, Liu B, Zhang C, Hammock BD. PMID: 31589045; PMCID: PMC7134064.
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    140. Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. Front Pharmacol. 2019; 10:1118. Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe DS, Kumar NG, Yang J, Hwang SH, Hammock BD, Sriramarao P, Rao SP. PMID: 31611798; PMCID: PMC6777353.
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    141. Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain. J Med Chem. 2019 09 26; 62(18):8443-8460. Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. PMID: 31436984; PMCID: PMC7262789.
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    142. Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicol Appl Pharmacol. 2019 11 01; 382:114749. Yang J, Bruun DA, Wang C, Wan D, McReynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. PMID: 31521729; PMCID: PMC6957308.
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    143. Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Cent Sci. 2019 Sep 25; 5(9):1614-1624. Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. PMID: 31572788; PMCID: PMC6764161.
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    144. Fluorescent "Turn off-on" Small-Molecule-Monitoring Nanoplatform Based on Dendrimer-like Peptides as Competitors. ACS Appl Mater Interfaces. 2019 Sep 11; 11(36):33380-33389. Chen H, Ding Y, Yang Q, Barnych B, González-Sapienza G, Hammock BD, Wang M, Hua X. PMID: 31433617; PMCID: PMC7059760.
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    145. A label-free optical whole-cell Escherichia coli biosensor for the detection of pyrethroid insecticide exposure. Sci Rep. 2019 08 28; 9(1):12466. Riangrungroj P, Bever CS, Hammock BD, Polizzi KM. PMID: 31462650; PMCID: PMC6713742.
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    146. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. Bioorg Med Chem. 2019 10 15; 27(20):115078. Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S. PMID: 31488357; PMCID: PMC6892585.
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    147. 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. ACS Chem Neurosci. 2019 09 18; 10(9):4018-4030. Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. PMID: 31378059; PMCID: PMC7028313.
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    148. Highly Specific Monoclonal Antibody and Sensitive Quantum Dot Beads-Based Fluorescence Immunochromatographic Test Strip for Tebuconazole Assay in Agricultural Products. J Agric Food Chem. 2019 Aug 14; 67(32):9096-9103. Wang Y, Xu J, Qiu Y, Li P, Liu B, Yang L, Barnych B, Hammock BD, Zhang C. PMID: 31356079; PMCID: PMC7069222.
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    149. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain Behav Immun. 2019 10; 81:545-559. Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock B, Vasylieva N, Hongsibsong S, Stern LJ, Crawford F, Mullan M, Abdullah L. PMID: 31325531; PMCID: PMC7155744.
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    151. Impact of the acute local inhibition of soluble epoxide hydrolase on diabetic skin microcirculatory dysfunction. Diab Vasc Dis Res. 2019 11; 16(6):523-529. Savina Y, Duflot T, Bounoure F, Kotzki S, Thiebaut PA, Serreau PA, Skiba M, Picquenot JM, Cornic M, Morisseau C, Hammock B, Imbert L, Cracowski JL, Richard V, Roustit M, Bellien J. PMID: 31267765; PMCID: PMC7307659.
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    152. Inhibition of Pancreatic Carcinoma Growth Through Enhancing ω-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase. Anticancer Res. 2019 Jul; 39(7):3651-3660. Xia R, Sun L, Liao J, Li H, You X, Xu D, Yang J, Hwang SH, Jones RD, Hammock B, Yang GY. PMID: 31262891; PMCID: PMC7117872.
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    153. Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice. Sci Rep. 2019 06 20; 9(1):8993. Klocke J, Ulu A, Wu K, Rudolph B, Dragun D, Gollasch M, Schunck WH, Hammock BD, Riemekasten G, Enghard P. PMID: 31222024; PMCID: PMC6586931.
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    154. Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. J Clin Invest. 2019 06 17; 129(7):2964-2979. Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, Sukhatme V, Hammock BD, Kieran MW, Huang S, Bhasin M, Serhan CN, Sukhatme VP. PMID: 31205032; PMCID: PMC6597207.
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    155. Cyclic peptide: a safe and effective alternative to synthetic aflatoxin B1-competitive antigens. Anal Bioanal Chem. 2019 Jul; 411(17):3881-3890. Mukhtar H, Ma L, Pang Q, Zhou Y, Wang X, Xu T, Hammock BD, Wang J. PMID: 31152222.
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    157. Computer-Aided Selective Optimization of Side Activities of Talinolol. ACS Med Chem Lett. 2019 Jun 13; 10(6):899-903. Hiesinger K, Kramer JS, Achenbach J, Moser D, Weber J, Wittmann SK, Morisseau C, Angioni C, Geisslinger G, Kahnt AS, Kaiser A, Proschak A, Steinhilber D, Pogoryelov D, Wagner K, Hammock BD, Proschak E. PMID: 31223445; PMCID: PMC6580380.
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    158. Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Front Pharmacol. 2019; 10:580. Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. PMID: 31191316; PMCID: PMC6548860.
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    159. N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase. Biochem Biophys Res Commun. 2019 07 12; 515(1):248-253. Matsumoto N, Kataoka M, Hirosaki H, Morisseau C, Hammock BD, Suzuki E, Hasumi K. PMID: 31146915; PMCID: PMC7395850.
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    160. Impact of diabetes on male sexual function in streptozotocin-induced diabetic rats: Protective role of soluble epoxide hydrolase inhibitor. Biomed Pharmacother. 2019 Jul; 115:108897. Minaz N, Razdan R, Hammock BD, Mujwar S, Goswami SK. PMID: 31102913; PMCID: PMC6893866.
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    161. Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly-horseradish peroxidase (PolyHRP). Electrophoresis. 2019 07; 40(12-13):1731-1739. Mishra M, Tiwari S, Gunaseelan A, Li D, Hammock BD, Gomes AV. PMID: 31021001; PMCID: PMC7036291.
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    162. In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Front Pharmacol. 2019; 10:464. Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. PMID: 31143115; PMCID: PMC6520522.
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    163. Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba. J Agric Food Chem. 2019 May 22; 67(20):5711-5719. Huo J, Barnych B, Li Z, Wan D, Li D, Vasylieva N, Knezevic SZ, Osipitan OA, Scott JE, Zhang J, Hammock BD. PMID: 31042038; PMCID: PMC6873229.
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    164. Nanobody-based fluorescence resonance energy transfer immunoassay for noncompetitive and simultaneous detection of ochratoxin a and ochratoxin B. Environ Pollut. 2019 Aug; 251:238-245. Tang Z, Liu X, Wang Y, Chen Q, Hammock BD, Xu Y. PMID: 31082608; PMCID: PMC7103568.
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    166. Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes. Front Pharmacol. 2019; 10:288. Pardeshi R, Bolshette N, Gadhave K, Arfeen M, Ahmed S, Jamwal R, Hammock BD, Lahkar M, Goswami SK. PMID: 31068802; PMCID: PMC6491817.
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    167. One-Step Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Fusion for Detection of Aflatoxin B1 in Cereal. J Agric Food Chem. 2019 May 08; 67(18):5221-5229. Ren W, Li Z, Xu Y, Wan D, Barnych B, Li Y, Tu Z, He Q, Fu J, Hammock BD. PMID: 30883117; PMCID: PMC7792509.
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    168. Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations. Int J Biol Macromol. 2019 Jul 15; 133:1187-1193. Liu ZB, Sun CP, Xu JX, Morisseau C, Hammock BD, Qiu F. PMID: 30980876.
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    169. Development of an immunoassay for the detection of carbaryl in cereals based on a camelid variable heavy-chain antibody domain. J Sci Food Agric. 2019 Jul; 99(9):4383-4390. Liu Z, Wang K, Wu S, Wang Z, Ding G, Hao X, Li QX, Li J, Gee SJ, Hammock BD, Xu T. PMID: 30851058; PMCID: PMC7061733.
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    171. Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats. Front Pharmacol. 2019; 10:159. Hrdlicka J, Neckár J, Papoušek F, Husková Z, Kikerlová S, Vanourková Z, Vernerová Z, Akat F, Vašinová J, Hammock BD, Hwang SH, Imig JD, Falck JR, Cervenka L, Kolár F. PMID: 30881303; PMCID: PMC6406051.
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    174. Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5154-5159. Luo Y, Wu MY, Deng BQ, Huang J, Hwang SH, Li MY, Zhou CY, Zhang QY, Yu HB, Zhao DK, Zhang G, Qin L, Peng A, Hammock BD, Liu JY. PMID: 30804206; PMCID: PMC6421466.
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    175. Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. Am J Physiol Gastrointest Liver Physiol. 2019 04 01; 316(4):G527-G538. Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y. PMID: 30789748; PMCID: PMC6483021.
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    176. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. Int J Biol Macromol. 2019 May 15; 129:653-658. de Oliveira GS, Adriani PP, Ribeiro JA, Morisseau C, Hammock BD, Dias MVB, Chambergo FS. PMID: 30771398; PMCID: PMC6447457.
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    177. Fluoroaromatic fragments on 1,3-disubstituted ureas enhance soluble epoxide hydrolase inhibition. J Fluor Chem. 2019 Apr; 220:48-53. Burmistrov V, Morisseau C, D'yachenko V, Rybakov VB, Butov GM, Hammock BD. PMID: 32132741; PMCID: PMC7055688.
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    183. Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity. Prostaglandins Other Lipid Mediat. 2019 02; 140:31-39. Hiesinger K, Wagner KM, Hammock BD, Proschak E, Hwang SH. PMID: 30593866; PMCID: PMC6345559.
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    184. Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays. Anal Chem. 2019 01 15; 91(2):1532-1540. Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. PMID: 30521755; PMCID: PMC7144541.
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    185. Competitive and noncompetitive immunoassays for the detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled peptides. Anal Bioanal Chem. 2019 Jan; 411(2):527-535. Chen H, Yang Q, Ding Y, Vasylieva N, Bever CS, Hua X, Wang M, Hammock BD. PMID: 30478514; PMCID: PMC7263471.
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    189. Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei. Mol Biol Rep. 2019 Feb; 46(1):371-379. de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS. PMID: 30426381; PMCID: PMC6426676.
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    190. Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. ACS Omega. 2018 Oct 31; 3(10):14076-14086. Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. PMID: 30411058; PMCID: PMC6210075.
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    191. Development of a Highly Sensitive Direct Competitive Fluorescence Enzyme Immunoassay Based on a Nanobody-Alkaline Phosphatase Fusion Protein for Detection of 3-Phenoxybenzoic Acid in Urine. J Agric Food Chem. 2018 Oct 31; 66(43):11284-11290. Huo J, Li Z, Wan D, Li D, Qi M, Barnych B, Vasylieva N, Zhang J, Hammock BD. PMID: 30293433; PMCID: PMC6442738.
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    192. Omega-3 PUFA attenuate mice myocardial infarction injury by emerging a protective eicosanoid pattern. Prostaglandins Other Lipid Mediat. 2018 11; 139:1-9. Fang X, Cai W, Cheng Q, Ai D, Wang X, Hammock BD, Zhu Y, Zhang X. PMID: 30223037.
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    193. Development of a Nanobody-AviTag Fusion Protein and Its Application in a Streptavidin-Biotin-Amplified Enzyme-Linked Immunosorbent Assay for Ochratoxin A in Cereal. Anal Chem. 2018 09 04; 90(17):10628-10634. Sun Z, Lv J, Liu X, Tang Z, Wang X, Xu Y, Hammock BD. PMID: 30092629; PMCID: PMC7307665.
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    194. Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A. Anal Bioanal Chem. 2018 Oct; 410(25):6633-6642. He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T. PMID: 30066195; PMCID: PMC7105167.
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    195. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. J Hypertens. 2018 06; 36(6):1326-1341. Cervenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vanourková Z, Alánová P, Kolár F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckár J. PMID: 29570510; PMCID: PMC7375140.
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    196. Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res. 2018 Oct; 53(5):743-749. Napimoga MH, Rocha EP, Trindade-da-Silva CA, Demasi APD, Martinez EF, Macedo CG, Abdalla HB, Bettaieb A, Haj FG, Clemente-Napimoga JT, Inceoglu B, Hammock BD. PMID: 29851077; PMCID: PMC6168335.
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    197. Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol. 2018 08; 94(2):834-841. Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD. PMID: 29844231; PMCID: PMC6022802.
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    198. Adamantyl thioureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2018 07 15; 28(13):2302-2313. Burmistrov V, Morisseau C, Pitushkin D, Karlov D, Fayzullin RR, Butov GM, Hammock BD. PMID: 29803731; PMCID: PMC6442743.
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    199. An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats. Prostaglandins Other Lipid Mediat. 2018 05; 136:84-89. Minaz N, Razdan R, Hammock BD, Goswami SK. PMID: 29751149; PMCID: PMC6402559.
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    200. Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):E5815-E5823. Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K. PMID: 29735655; PMCID: PMC6016799.
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    201. Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling. Anal Chem. 2018 05 15; 90(10):6187-6192. Lassabe G, Kramer K, Hammock BD, González-Sapienza G, González-Techera A. PMID: 29694028; PMCID: PMC5963685.
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    202. Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):5283-5288. Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G. PMID: 29717038; PMCID: PMC5960306.
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    203. Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. Analyst. 2018 Apr 30; 143(9):2057-2065. Cui X, Vasylieva N, Shen D, Barnych B, Yang J, He Q, Jiang Z, Zhao S, Hammock BD. PMID: 29629470; PMCID: PMC6449042.
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    204. Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J Med Chem. 2018 05 10; 61(9):4271. Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 29701466; PMCID: PMC5949719.
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    205. Celecoxib use and circulating oxylipins in a colon polyp prevention trial. PLoS One. 2018; 13(4):e0196398. Martinez JA, Yang J, Wertheim BC, Roe DJ, Schriewer A, Lance P, Alberts DS, Hammock BD, Thompson PA. PMID: 29698447; PMCID: PMC5919576.
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    206. Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem. 2018 04 26; 61(8):3541-3550. Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. PMID: 29614224; PMCID: PMC5933862.
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    207. Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere. 2018 Jul; 203:467-473. Bever CS, Rand AA, Nording M, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. PMID: 29635158; PMCID: PMC5915298.
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    208. Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2018 03 27; 8(1):5279. Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 29588470; PMCID: PMC5869703.
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    209. Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther. 2018 06; 365(3):467-475. Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S. PMID: 29567865; PMCID: PMC5931432.
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    210. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat. 2018 05; 136:90-95. Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. PMID: 29567338; PMCID: PMC5970965.
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    211. Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula. Physiol Res. 2018 07 17; 67(3):401-415. Kala P, Sedláková L, Škaroupková P, Kopkan L, Vanourková Z, Táborský M, Nishiyama A, Hwang SH, Hammock BD, Sadowski J, Melenovský V, Imig JD, Cervenka L. PMID: 29527914; PMCID: PMC6056335.
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    212. Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney Blood Press Res. 2018; 43(2):329-349. Certíková Chábová V, Kujal P, Škaroupková P, Varnourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesar V, Cervenka L. PMID: 29529602; PMCID: PMC5985203.
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    213. Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function. J Lipid Res. 2018 04; 59(4):684-695. Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR. PMID: 29459481; PMCID: PMC5880498.
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    214. Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target. Neurosci Biobehav Rev. 2018 04; 87:56-66. Swardfager W, Hennebelle M, Yu D, Hammock BD, Levitt AJ, Hashimoto K, Taha AY. PMID: 29407524; PMCID: PMC5860823.
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    215. Phage-Mediated Competitive Chemiluminescent Immunoassay for Detecting Cry1Ab Toxin by Using an Anti-Idiotypic Camel Nanobody. J Agric Food Chem. 2018 Jan 31; 66(4):950-956. Qiu Y, Li P, Dong S, Zhang X, Yang Q, Wang Y, Ge J, Hammock BD, Zhang C, Liu X. PMID: 29293334; PMCID: PMC7314401.
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    216. Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation. J Leukoc Biol. 2018 07; 104(1):109-122. Bastan I, Ge XN, Dileepan M, Greenberg YG, Guedes AG, Hwang SH, Hammock BD, Washabau RJ, Rao SP, Sriramarao P. PMID: 29345370; PMCID: PMC6020675.
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    217. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett. 2018 02 15; 28(4):762-768. Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. PMID: 29366648; PMCID: PMC5837813.
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    218. Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation. Proc Natl Acad Sci U S A. 2018 01 16; 115(3):613-618. Yang YM, Sun D, Kandhi S, Froogh G, Zhuge J, Huang W, Hammock BD, Huang A. PMID: 29295935; PMCID: PMC5776989.
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    219. Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. J Alzheimers Dis. 2018; 62(4):1663-1681. Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Erakovic Haber V, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L. PMID: 29504531; PMCID: PMC7065497.
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    220. LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide. Methods Mol Biol. 2018; 1730:123-133. Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C. PMID: 29363071; PMCID: PMC5831730.
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    221. Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability. Bioorg Chem. 2018 02; 76:510-527. Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD. PMID: 29310082; PMCID: PMC5837815.
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    222. COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. Mol Cancer Ther. 2018 02; 17(2):474-483. Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, de Vere White RW, Pan CX. PMID: 29284644; PMCID: PMC5824635.
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    223. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017 12 14; 552(7684):248-252. Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I. PMID: 29211719; PMCID: PMC5828869.
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    224. Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal. 2018 Feb 05; 149:457-464. Lakkappa N, Krishnamurthy PT, Yamjala K, Hwang SH, Hammock BD, Babu B. PMID: 29169114; PMCID: PMC5843369.
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    225. Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12608-12613. Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY. PMID: 29109264; PMCID: PMC5703276.
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    226. Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis. J Vet Pharmacol Ther. 2018 Apr; 41(2):230-238. Guedes AGP, Aristizabal F, Sole A, Adedeji A, Brosnan R, Knych H, Yang J, Hwang SH, Morisseau C, Hammock BD. PMID: 29067696; PMCID: PMC5920688.
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    227. Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts. Anal Biochem. 2017 12 15; 539:81-89. Kodani SD, Barthélemy M, Kamita SG, Hammock B, Morisseau C. PMID: 29054529; PMCID: PMC5696082.
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    228. Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies. Anal Chem. 2017 10 17; 89(20):11091-11097. Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. PMID: 28942640; PMCID: PMC6459402.
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    229. Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice. Sci Rep. 2017 10 02; 7(1):12488. Deol P, Fahrmann J, Yang J, Evans JR, Rizo A, Grapov D, Salemi M, Wanichthanarak K, Fiehn O, Phinney B, Hammock BD, Sladek FM. PMID: 28970503; PMCID: PMC5624939.
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    230. COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor. Oncotarget. 2017 Oct 20; 8(50):87353-87363. Li J, Zhou Y, Wang H, Gao Y, Li L, Hwang SH, Ji X, Hammock BD. PMID: 29152086; PMCID: PMC5675638.
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    231. Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:68-78. Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. PMID: 28847566; PMCID: PMC5824649.
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    232. Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7545-E7553. Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. PMID: 28827330; PMCID: PMC5594641.
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    233. Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2758-2765. Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. PMID: 28757338; PMCID: PMC5873293.
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    234. Postprandial effect to decrease soluble epoxide hydrolase activity: roles of insulin and gut microbiota. J Nutr Biochem. 2017 11; 49:8-14. Yang J, Oh YT, Wan D, Watanabe RM, Hammock BD, Youn JH. PMID: 28863368; PMCID: PMC5858941.
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    235. Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Sci Rep. 2017 06 28; 7(1):4342. Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. PMID: 28659576; PMCID: PMC5489485.
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    236. Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. J Med Chem. 2017 07 13; 60(13):5392-5406. Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRR, Rana S, Contreras JI, Sahoo R, Wan D, Young J, Dias Teixeira KL, Morisseau C, Halperin J, Hammock B, Natarajan A, Wang P, Chorev M, Aktas BH. PMID: 28590739; PMCID: PMC5567831.
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    237. Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases. Pharmacol Ther. 2017 Dec; 180:62-76. Wagner KM, McReynolds CB, Schmidt WK, Hammock BD. PMID: 28642117; PMCID: PMC5677555.
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    238. Shexiang Baoxin pills promotes angiogenesis in myocardial infarction rats via up-regulation of 20-HETE-mediated endothelial progenitor cells mobilization. Atherosclerosis. 2017 08; 263:184-191. Huang F, Liu Y, Yang X, Che D, Qiu K, Hammock BD, Wang J, Wang MH, Chen J, Huang H. PMID: 28646793; PMCID: PMC5828780.
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    239. Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats. Cardiovasc Ther. 2017 Jun; 35(3). Islam O, Patil P, Goswami SK, Razdan R, Inamdar MN, Rizwan M, Mathew J, Inceoglu B, Stephen Lee KS, Hwang SH, Hammock BD. PMID: 28296232; PMCID: PMC5597338.
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    240. Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472. Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. PMID: 28411375; PMCID: PMC5808876.
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    241. Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury. FEBS J. 2017 07; 284(13):1970-1986. Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG. PMID: 28485854; PMCID: PMC5515292.
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    242. Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs. Org Biomol Chem. 2017 May 23; 15(20):4308-4313. Barnych B, Rand AA, Cajka T, Lee KSS, Hammock BD. PMID: 28470279; PMCID: PMC5527127.
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    243. Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers. Life Sci. 2017 Jul 01; 180:114-122. Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD. PMID: 28522175; PMCID: PMC5659729.
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    244. Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP? Anal Chem. 2017 06 06; 89(11):6248-6256. Li D, Cui Y, Morisseau C, Gee SJ, Bever CS, Liu X, Wu J, Hammock BD, Ying Y. PMID: 28460522; PMCID: PMC5611449.
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    245. Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus. Front Microbiol. 2017; 8:831. Fischer GJ, Bacon W, Yang J, Palmer JM, Dagenais T, Hammock BD, Keller NP. PMID: 28536571; PMCID: PMC5422543.
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    246. Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L252-L266. Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. PMID: 28473326; PMCID: PMC5582936.
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    247. Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales. PLoS One. 2017; 12(5):e0176571. Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD. PMID: 28472063; PMCID: PMC5417501.
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    248. Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice. Shock. 2017 05; 47(5):638-645. Zhou Y, Liu T, Duan JX, Li P, Sun GY, Liu YP, Zhang J, Dong L, Lee KSS, Hammock BD, Jiang JX, Guan CX. PMID: 27753791; PMCID: PMC5382142.
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    249. EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L350-L359. Kandhi S, Zhang B, Froogh G, Qin J, Alruwaili N, Le Y, Yang YM, Hwang SH, Hammock BD, Wolin MS, Huang A, Sun D. PMID: 28450284; PMCID: PMC5582931.
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    250. Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine. Anal Chem. 2017 05 16; 89(10):5612-5619. Vasylieva N, Barnych B, Rand A, Inceoglu B, Gee SJ, Hammock BD. PMID: 28398746; PMCID: PMC5920647.
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    251. In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. Drug Metab Dispos. 2017 07; 45(7):712-720. Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z. PMID: 28428366; PMCID: PMC5452678.
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    252. Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids. FASEB J. 2017 08; 31(8):3229-3239. Fiala M, Kooij G, Wagner K, Hammock B, Pellegrini M. PMID: 28420693; PMCID: PMC5503712.
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    253. Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids. Proc Natl Acad Sci U S A. 2017 04 25; 114(17):4370-4375. Rand AA, Barnych B, Morisseau C, Cajka T, Lee KSS, Panigrahy D, Hammock BD. PMID: 28396419; PMCID: PMC5410821.
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    254. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure. 2017 05 02; 25(5):697-707.e4. Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR. PMID: 28392259; PMCID: PMC5524515.
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    255. Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF. Chemosphere. 2017 Aug; 180:169-177. Chu S, Baker MR, Leong G, Letcher RJ, Gee SJ, Hammock BD, Li QX. PMID: 28407546; PMCID: PMC5494263.
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    256. Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis. J Pharmacol Exp Ther. 2017 06; 361(3):408-416. Trindade-da-Silva CA, Bettaieb A, Napimoga MH, Lee KSS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD. PMID: 28356494; PMCID: PMC5443319.
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    257. Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environ Int. 2017 06; 103:91-98. Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. PMID: 28343720; PMCID: PMC5432128.
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    258. Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behav Brain Res. 2017 05 30; 326:69-76. Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. PMID: 28259677; PMCID: PMC5409858.
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    259. Lipidomic Analysis of Oxidized Fatty Acids in Plant and Algae Oils. J Agric Food Chem. 2017 Mar 08; 65(9):1941-1951. Richardson CE, Hennebelle M, Otoki Y, Zamora D, Yang J, Hammock BD, Taha AY. PMID: 28157307; PMCID: PMC5581005.
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    260. Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study. Psychiatry Res. 2017 06; 252:94-101. Hennebelle M, Otoki Y, Yang J, Hammock BD, Levitt AJ, Taha AY, Swardfager W. PMID: 28259037; PMCID: PMC5611448.
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    261. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1382-1391. Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. PMID: 28185955; PMCID: PMC5608514.
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    262. A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine. J Lipid Res. 2017 04; 58(4):798-808. Wan D, Yang J, Barnych B, Hwang SH, Lee KSS, Cui Y, Niu J, Watsky MA, Hammock BD. PMID: 28148721; PMCID: PMC5392736.
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    263. Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. J Neurochem. 2017 03; 140(5):814-825. Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A. PMID: 28002622; PMCID: PMC5310989.
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    264. Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes. Plast Reconstr Surg Glob Open. 2016 Dec; 4(12):e1151. Supp DM, Hahn JM, McFarland KL, Combs KA, Lee KS, Inceoglu B, Wan D, Boyce ST, Hammock BD. PMID: 28293507; PMCID: PMC5222652.
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    265. Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators. Proc Natl Acad Sci U S A. 2017 01 03; 114(1):136-141. Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM. PMID: 27980032; PMCID: PMC5224368.
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    266. Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorg Med Chem Lett. 2017 02 01; 27(3):620-625. Hwang SH, Wagner K, Xu J, Yang J, Li X, Cao Z, Morisseau C, Lee KS, Hammock BD. PMID: 28025003; PMCID: PMC5584617.
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    267. Effects of high-fat diet on plasma profiles of eicosanoid metabolites in mice. Prostaglandins Other Lipid Mediat. 2016 12; 127:9-13. Wang W, Yang J, Yang H, Sanidad KZ, Hammock BD, Kim D, Zhang G. PMID: 27913146; PMCID: PMC5628263.
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    268. Lipidomic profiling of high-fat diet-induced obesity in mice: Importance of cytochrome P450-derived fatty acid epoxides. Obesity (Silver Spring). 2017 01; 25(1):132-140. Wang W, Yang J, Qi W, Yang H, Wang C, Tan B, Hammock BD, Park Y, Kim D, Zhang G. PMID: 27891824; PMCID: PMC5182168.
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    269. Nanobody-based enzyme immunoassay for ochratoxin A in cereal with high resistance to matrix interference. Talanta. 2017 Mar 01; 164:154-158. Liu X, Tang Z, Duan Z, He Z, Shu M, Wang X, Gee SJ, Hammock BD, Xu Y. PMID: 28107910; PMCID: PMC5862147.
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    270. Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Arch Biochem Biophys. 2017 Jan 01; 613:1-11. Lee KS, Henriksen NM, Ng CJ, Yang J, Jia W, Morisseau C, Andaya A, Gilson MK, Hammock BD. PMID: 27983948; PMCID: PMC5172606.
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    271. A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents. Mitochondrion. 2016 Nov; 31:79-83. Datta S, Sahdeo S, Gray JA, Morriseau C, Hammock BD, Cortopassi G. PMID: 27717841; PMCID: PMC5108672.
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    272. Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere. 2017 Jan; 166:511-520. Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. PMID: 27710886; PMCID: PMC5560107.
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    273. Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use. J Ethnopharmacol. 2016 Dec 24; 194:475-482. Liu JY, Morisseau C, Huang H, Hammock BD. PMID: 27702689; PMCID: PMC5584568.
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    274. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16; 262:92-99. Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. PMID: 27659731; PMCID: PMC5096949.
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    275. Epoxy fatty acids mediate analgesia in murine diabetic neuropathy. Eur J Pain. 2017 03; 21(3):456-465. Wagner K, Lee KS, Yang J, Hammock BD. PMID: 27634339; PMCID: PMC5300894.
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    277. Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis. Equine Vet J. 2017 May; 49(3):345-351. Guedes A, Galuppo L, Hood D, Hwang SH, Morisseau C, Hammock BD. PMID: 27338788; PMCID: PMC5580818.
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    278. Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol. 2016 Nov 15; 223:923-935. Ghosh R, Goswami SK, Feitoza LFBB, Hammock B, Gomes AV. PMID: 27589040; PMCID: PMC5076377.
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    279. Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice. J Mol Cell Cardiol. 2016 09; 98:128-37. Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan LM, Hammock BD, Ai D, Zhu Y. PMID: 27496380; PMCID: PMC5559083.
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    280. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. PMID: 27467073; PMCID: PMC5063690.
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    281. A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat. Prostaglandins Other Lipid Mediat. 2016 09; 125:40-7. Hye Khan MA, Hwang SH, Sharma A, Corbett JA, Hammock BD, Imig JD. PMID: 27432695; PMCID: PMC5035206.
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    282. Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1919-27. Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellström A, Hammock BD, Zeldin DC, Smith LE. PMID: 27417579; PMCID: PMC5010176.
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    283. Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. Insect Biochem Mol Biol. 2016 09; 76:62-69. Xu J, Morisseau C, Yang J, Lee KSS, Kamita SG, Hammock BD. PMID: 27369469; PMCID: PMC5010450.
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    284. Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury. Front Pharmacol. 2016; 7:133. Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM. PMID: 27375480; PMCID: PMC4896112.
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    285. Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders. Med Hypotheses. 2016 Aug; 93:161-5. Lakkappa N, Krishnamurthy PT, Hammock BD, Velmurugan D, Bharath MM. PMID: 27372879; PMCID: PMC4985172.
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    286. Erratum to: Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 06; 364(3):675. Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26946414.
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    287. Inhibition of soluble epoxide hydrolase as a novel approach to high dose diazepam induced hypotension. J Clin Toxicol. 2016 Jun; 6(3). Ulu A, Inceoglu B, Yang J, Singh V, Vito S, Wulff H, Hammock BD. PMID: 28255523; PMCID: PMC5328659.
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    288. VHH antibodies: emerging reagents for the analysis of environmental chemicals. Anal Bioanal Chem. 2016 Sep; 408(22):5985-6002. Bever CS, Dong JX, Vasylieva N, Barnych B, Cui Y, Xu ZL, Hammock BD, Gee SJ. PMID: 27209591; PMCID: PMC4983233.
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    289. Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. Int J Mol Sci. 2016 May 18; 17(5). Sharma A, Hye Khan MA, Levick SP, Lee KS, Hammock BD, Imig JD. PMID: 27213332; PMCID: PMC4881572.
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    290. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats. Toxicol Sci. 2016 08; 152(2):309-22. Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. PMID: 27208083; PMCID: PMC4960907.
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    291. Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins Leukot Essent Fatty Acids. 2018 11; 138:71-80. Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE. PMID: 27282298; PMCID: PMC5106341.
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    292. Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorg Med Chem. 2016 10 15; 24(20):4801-4811. Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. PMID: 27320659; PMCID: PMC5053890.
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    293. Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa. J Med Chem. 2016 05 26; 59(10):4790-9. Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C. PMID: 27120257; PMCID: PMC4957648.
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    294. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5). Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. PMID: 27162031; PMCID: PMC4869994.
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    295. Quantification of GST and esterase activities in pyrethrin-resistant mosquitoes using pyrethroid-like fluorescent substrates. Int J Pest Manag. 2016; 62(4):276-283. Kamita SG, Mulligan S, Cornel AJ, Hammock BD. PMID: 28736488; PMCID: PMC5516934.
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    296. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. J Mol Cell Cardiol. 2016 05; 94:180-188. Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. PMID: 27079253; PMCID: PMC4972711.
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    297. Anti-idiotypic nanobody-alkaline phosphatase fusion proteins: Development of a one-step competitive enzyme immunoassay for fumonisin B1 detection in cereal. Anal Chim Acta. 2016 Jun 14; 924:53-59. Shu M, Xu Y, Liu X, Li Y, He Q, Tu Z, Fu J, Gee SJ, Hammock BD. PMID: 27181644.
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    298. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61. Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. PMID: 26937944; PMCID: PMC4821808.
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    299. Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther. 2016 06; 357(3):529-36. Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. PMID: 26989141; PMCID: PMC4885505.
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    300. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):E1944-52. Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. PMID: 26976569; PMCID: PMC4822604.
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    301. Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? Mol Pain. 2016; 12. Ramsden CE, Ringel A, Majchrzak-Hong SF, Yang J, Blanchard H, Zamora D, Loewke JD, Rapoport SI, Hibbeln JR, Davis JM, Hammock BD, Taha AY. PMID: 27030719; PMCID: PMC4955998.
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    302. Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates. Drug Metab Dispos. 2016 May; 44(5):771-80. Zhao Y, Wan D, Yang J, Hammock BD, Ortiz de Montellano PR. PMID: 26936974; PMCID: PMC4851306.
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    303. Addition of DHA Synergistically Enhances the Efficacy of Regorafenib for Kidney Cancer Therapy. Mol Cancer Ther. 2016 05; 15(5):890-8. Kim J, Ulu A, Wan D, Yang J, Hammock BD, Weiss RH. PMID: 26921392; PMCID: PMC4873345.
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    304. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 2016 Mar; 92:30-40. Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C. PMID: 26812119; PMCID: PMC5008453.
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    305. Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (Lond). 2016 Feb; 11(4):377-90. Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. PMID: 26786134; PMCID: PMC4910953.
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    306. Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. J Ocul Biol. 2016 Jan; 4(1). McLellan GJ, Aktas Z, Hennes-Beean E, Kolb AW, Larsen IV, Schmitz EJ, Clausius HR, Yang J, Hwang SH, Morisseau C, Inceoglu B, Hammock BD, Brandt CR. PMID: 28066796; PMCID: PMC5218821.
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    307. Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery. J Lipid Res. 2016 Mar; 57(3):492-8. Akintoye E, Wu JH, Hou T, Song X, Yang J, Hammock B, Mozaffarian D. PMID: 26749073; PMCID: PMC4766998.
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    308. Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-KrasG¹²D/Pdx-1-Cre Mice. Anticancer Res. 2016 Jan; 36(1):27-37. Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY. PMID: 26722025; PMCID: PMC4793710.
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    309. Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. PLoS One. 2015; 10(12):e0144996. Berthelot CC, Kamita SG, Sacchi R, Yang J, Nording ML, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Hammock BD, Zivkovic AM. PMID: 26672987; PMCID: PMC4681469.
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    310. Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Lett. 2016 Feb 28; 371(2):187-93. Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY. PMID: 26683769; PMCID: PMC4738175.
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    311. Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays. Anal Chem. 2015 Dec 01; 87(23):11907-14. Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever CS, Lee KS, Morisseau C, Leizagoyen C, Gee S, Hammock BD, González-Sapienza G. PMID: 26544909; PMCID: PMC4666776.
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    312. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model. Toxicol Appl Pharmacol. 2015 Dec 15; 289(3):419-27. Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. PMID: 26522832; PMCID: PMC4666679.
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    313. 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2015 Dec 01; 25(23):5514-9. Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. PMID: 26520661; PMCID: PMC4654407.
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    314. Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase. Bioorg Med Chem. 2015 Nov 15; 23(22):7199-210. Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K. PMID: 26507430.
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    315. Effects of juvenile hormone (JH) analog insecticides on larval development and JH esterase activity in two spodopterans. Pestic Biochem Physiol. 2016 Mar; 128:30-6. El-Sheikh el-SA, Kamita SG, Hammock BD. PMID: 26969437.
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    316. In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochem Pharmacol. 2015 Dec 15; 98(4):718-31. Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. PMID: 26494425; PMCID: PMC4656071.
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    317. Soluble epoxide hydrolase is involved in the development of atherosclerosis and arterial neointima formation by regulating smooth muscle cell migration. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1894-903. Wang Q, Huo L, He J, Ding W, Su H, Tian D, Welch C, Hammock BD, Ai D, Zhu Y. PMID: 26453326.
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    318. Aerobic exercise-based rehabilitation affects the activities of progenitor endothelial cells through EETs pathway. Med Hypotheses. 2015 Dec; 85(6):1037-8. Deng LM, Li XP, Xu DY, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 26454561; PMCID: PMC5003087.
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    319. Vitamin D in Tear Fluid. Invest Ophthalmol Vis Sci. 2015 Sep; 56(10):5880-7. Lu X, Elizondo RA, Nielsen R, Christensen EI, Yang J, Hammock BD, Watsky MA. PMID: 26348637; PMCID: PMC4566401.
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    320. Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 02; 363(2):399-409. Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26310139; PMCID: PMC4738109.
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    321. Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Anal Chim Acta. 2015 Aug 26; 890:150-6. Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. PMID: 26347177; PMCID: PMC4791039.
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    322. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem. 2015 Sep; 407(24):7263-73. Ranganathan A, Gee SJ, Hammock BD. PMID: 26255293; PMCID: PMC4580343.
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    323. Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environ Sci Technol. 2015 Aug 18; 49(16):10038-47. Vasylieva N, Ahn KC, Barnych B, Gee SJ, Hammock BD. PMID: 26196357; PMCID: PMC4605820.
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    324. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem. 2015 Sep; 407(24):7275-83. Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD. PMID: 26229025; PMCID: PMC4573264.
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    325. The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. Am J Physiol Renal Physiol. 2015 Sep 15; 309(6):F492-8. Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock B, Bell PD, Guay-Woodford LM, Weiss RH. PMID: 26155843; PMCID: PMC4572393.
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    326. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9082-7. Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. PMID: 26150506; PMCID: PMC4517273.
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    327. Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew Chem Int Ed Engl. 2015 Aug 17; 54(34):9881-5. Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. PMID: 26136396; PMCID: PMC4556431.
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    328. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat. 2015 Sep; 121(Pt A):131-7. Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. PMID: 26117215; PMCID: PMC4688279.
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    329. Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins. Biochem Biophys Res Commun. 2015 Aug 07; 463(4):774-80. Thomson S, Edin ML, Lih FB, Davies M, Yaqoob MM, Hammock BD, Gilroy D, Zeldin DC, Bishop-Bailey D. PMID: 26086108; PMCID: PMC4533761.
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    330. Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula. Physiol Res. 2015; 64(6):857-73. Cervenka L, Melenovský V, Husková Z, Sporková A, Bürgelová M, Škaroupková P, Hwang SH, Hammock BD, Imig JD, Sadowski J. PMID: 26047375; PMCID: PMC4984848.
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    331. Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice. Physiol Rep. 2015 Jun; 3(6). Qin J, Sun D, Jiang H, Kandhi S, Froogh G, Hwang SH, Hammock BD, Wolin MS, Thompson CI, Hintze TH, Huang A. PMID: 26071213; PMCID: PMC4510629.
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    332. High salt intake increases blood pressure in normal rats: putative role of 20-HETE and no evidence on changes in renal vascular reactivity. Kidney Blood Press Res. 2015; 40(3):323-34. Walkowska A, Kuczeriszka M, Sadowski J, Olszyñski KH, Dobrowolski L, Cervenka L, Hammock BD, Kompanowska-Jezierska E. PMID: 26067851; PMCID: PMC4583220.
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    333. Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. Mol Pharmacol. 2015 Aug; 88(2):281-90. Bettaieb A, Chahed S, Bachaalany S, Griffey S, Hammock BD, Haj FG. PMID: 25993999; PMCID: PMC4518092.
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    334. One-step immunoassay for tetrabromobisphenol a using a camelid single domain antibody-alkaline phosphatase fusion protein. Anal Chem. 2015; 87(9):4741-8. Wang J, Majkova Z, Bever CR, Yang J, Gee SJ, Li J, Xu T, Hammock BD. PMID: 25849972; PMCID: PMC4476793.
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    335. Development of an enzyme-linked immunosorbent assay for thiacloprid in soil and agro-products with phage-displayed peptide. Anal Biochem. 2015 Jul 15; 481:27-32. Yin W, Hua X, Liu X, Shi H, Gee SJ, Wang M, Hammock BD. PMID: 25908560.
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    336. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacol Res. 2015 Jul; 97:7-15. Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. PMID: 25882247; PMCID: PMC4464910.
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    337. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. PMID: 25882826; PMCID: PMC4466064.
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    338. Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E978-89. Fahrmann J, Grapov D, Yang J, Hammock B, Fiehn O, Bell GI, Hara M. PMID: 25852003; PMCID: PMC4451288.
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    339. Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. J Metabolomics. 2015 Apr; 1. Nording ML, Yang J, Hoang L, Zamora V, Uyeminami D, Espiritu I, Pinkerton KE, Hammock BD, Luria A. PMID: 27076918; PMCID: PMC4827720.
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    340. Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa. Mol Psychiatry. 2016 Apr; 21(4):537-46. Shih PB, Yang J, Morisseau C, German JB, Zeeland AA, Armando AM, Quehenberger O, Bergen AW, Magistretti P, Berrettini W, Halmi KA, Schork N, Hammock BD, Kaye W. PMID: 25824304; PMCID: PMC4591075.
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    341. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):102-11. Harris TR, Bettaieb A, Kodani S, Dong H, Myers R, Chiamvimonvat N, Haj FG, Hammock BD. PMID: 25827057; PMCID: PMC4458210.
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    342. The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain. Drug Metab Dispos. 2015 May; 43(5):788-802. Kodani SD, Hammock BD. PMID: 25762541; PMCID: PMC4407705.
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    343. Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection. J Insect Physiol. 2015 Sep; 80:71-80. Saito Y, Kamita SG, Hammock BD, Kunimi Y, Inoue MN, Nakai M. PMID: 25727179.
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    344. A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase. Chembiochem. 2015 Mar 23; 16(5):766-71. Nollmann FI, Heinrich AK, Brachmann AO, Morisseau C, Mukherjee K, Casanova-Torres ÁM, Strobl F, Kleinhans D, Kinski S, Schultz K, Beeton ML, Kaiser M, Chu YY, Phan Ke L, Thanwisai A, Bozhüyük KA, Chantratita N, Götz F, Waterfield NR, Vilcinskas A, Stelzer EH, Goodrich-Blair H, Hammock BD, Bode HB. PMID: 25711603; PMCID: PMC4486325.
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    345. Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis. Atherosclerosis. 2015 Apr; 239(2):557-65. Shen L, Peng H, Peng R, Fan Q, Zhao S, Xu D, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 25733327; PMCID: PMC4527317.
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    346. Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. Insect Biochem Mol Biol. 2015 Apr; 59:41-9. Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD. PMID: 25686802; PMCID: PMC4387068.
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    347. Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo. PLoS One. 2015; 10(2):e0117438. Kitamura S, Morisseau C, Inceoglu B, Kamita SG, De Nicola GR, Nyegue M, Hammock BD. PMID: 25659109; PMCID: PMC4319826.
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    348. Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal. Anal Chem. 2015 Jan 20; 87(2):1387-94. Liu X, Xu Y, Wan DB, Xiong YH, He ZY, Wang XX, Gee SJ, Ryu D, Hammock BD. PMID: 25531426; PMCID: PMC4476795.
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    349. Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2015 Jan; 52(1):46-55. Yang J, Bratt J, Franzi L, Liu JY, Zhang G, Zeki AA, Vogel CF, Williams K, Dong H, Lin Y, Hwang SH, Kenyon NJ, Hammock BD. PMID: 24922186; PMCID: PMC4370250.
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    350. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):536-41. López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J. PMID: 25550510; PMCID: PMC4299190.
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    351. Soluble epoxide hydrolase deficiency ameliorates acute pancreatitis in mice. Free Radic Biol Med. 2014 Oct; 75 Suppl 1:S32. Bettaieb A, Morisseau C, Hammock B, Haj F. PMID: 26461340.
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    352. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clin Exp Pharmacol Physiol. 2014 Dec; 41(12):1003-13. Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. PMID: 25224811; PMCID: PMC4347520.
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    353. Identification of potent inhibitors of the chicken soluble epoxide hydrolase. Bioorg Med Chem Lett. 2015 Jan 15; 25(2):276-9. Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. PMID: 25479771; PMCID: PMC4277729.
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    354. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemother Pharmacol. 2015 Jan; 75(1):161-71. Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. PMID: 25413440; PMCID: PMC4400119.
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    355. Editorial: 15th International Winter Eicosanoid Conference. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:1. Panigrahy D, Hammock B. PMID: 25453874.
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    356. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. PLoS One. 2014; 9(11):e113019. Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. PMID: 25402489; PMCID: PMC4234494.
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    357. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17200-5. Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. PMID: 25404284; PMCID: PMC4260592.
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    358. A lipid gate for the peripheral control of pain. J Neurosci. 2014 Nov 12; 34(46):15184-91. Piomelli D, Hohmann AG, Seybold V, Hammock BD. PMID: 25392487; PMCID: PMC4228127.
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    359. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol. 2015 Jan-Feb; 47:36-45. Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ. PMID: 25446016; PMCID: PMC4291292.
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    360. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics. 2014 Nov; 8(6):064101. Chen A, Wang R, Bever CR, Xing S, Hammock BD, Pan T. PMID: 25553178; PMCID: PMC4241779.
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    361. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. Am J Physiol Renal Physiol. 2015 Jan 15; 308(2):F131-9. Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. PMID: 25377915; PMCID: PMC4338924.
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    362. Structure of the OsSERK2 leucine-rich repeat extracellular domain. Acta Crystallogr D Biol Crystallogr. 2014 Nov; 70(Pt 11):3080-6. McAndrew R, Pruitt RN, Kamita SG, Pereira JH, Majumdar D, Hammock BD, Adams PD, Ronald PC. PMID: 25372696; PMCID: PMC4220978.
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    363. Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):886-97. Ono E, Dutile S, Kazani S, Wechsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland ER, Castro M, Jarjour NN, Israel E, Levy BD, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 25162465; PMCID: PMC4299578.
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    364. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicol Appl Pharmacol. 2014 Dec 01; 281(2):185-94. Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. PMID: 25448683; PMCID: PMC4258121.
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    365. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicol Lett. 2015 Jan 05; 232(1):10-20. Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM. PMID: 25300478; PMCID: PMC4486642.
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    366. The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:2-12. Wagner K, Vito S, Inceoglu B, Hammock BD. PMID: 25240260; PMCID: PMC4254344.
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    367. Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model. J Vasc Res. 2014; 51(4):269-82. Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK. PMID: 25196102; PMCID: PMC4235611.
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    368. Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids. Insect Biochem Mol Biol. 2014 Nov; 54:42-52. Xu J, Morisseau C, Hammock BD. PMID: 25173592; PMCID: PMC4252830.
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    369. Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. Am J Physiol Renal Physiol. 2014 Oct 15; 307(8):F971-80. Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ. PMID: 25164080; PMCID: PMC4200297.
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    370. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. J Am Heart Assoc. 2014 Aug 21; 3(4). Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. PMID: 25146704; PMCID: PMC4310392.
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    371. Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green. J Agric Food Chem. 2014 Aug 27; 62(34):8752-8. Dong JX, Xu C, Wang H, Xiao ZL, Gee SJ, Li ZF, Wang F, Wu WJ, Shen YD, Yang JY, Sun YM, Hammock BD. PMID: 25077381; PMCID: PMC4150606.
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    372. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 2014 Aug 28; 57(16):7016-30. Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 25079952; PMCID: PMC4148150.
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    373. Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products. Anal Chem. 2014 Aug 19; 86(16):8441-7. Hua X, Yin W, Shi H, Li M, Wang Y, Wang H, Ye Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. PMID: 25135320; PMCID: PMC4139188.
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    374. Heterologous antigen selection of camelid heavy chain single domain antibodies against tetrabromobisphenol A. Anal Chem. 2014 Aug 19; 86(16):8296-302. Wang J, Bever CR, Majkova Z, Dechant JE, Yang J, Gee SJ, Xu T, Hammock BD. PMID: 25068372; PMCID: PMC4139172.
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    375. VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal. Anal Chem. 2014 Aug 05; 86(15):7471-7. Liu X, Xu Y, Xiong YH, Tu Z, Li YP, He ZY, Qiu YL, Fu JH, Gee SJ, Hammock BD. PMID: 24992514; PMCID: PMC4306448.
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    376. Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3062-71. Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, Green MR, Wajapeyee N. PMID: 25024194; PMCID: PMC4121806.
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    377. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):11127-32. Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 25024195; PMCID: PMC4121808.
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    378. ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:13-20. Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G. PMID: 25019221; PMCID: PMC4306447.
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    379. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal Chem. 2014 Aug 05; 86(15):7875-82. Bever CR, Majkova Z, Radhakrishnan R, Suni I, McCoy M, Wang Y, Dechant J, Gee S, Hammock BD. PMID: 25005746; PMCID: PMC4144723.
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    380. Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core. Eur J Med Chem. 2014 Sep 12; 84:160-72. Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. PMID: 25016374.
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    381. An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2014 Jul; 64(1):87-99. Ulu A, Stephen Lee KS, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD. PMID: 24691274; PMCID: PMC4092041.
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    382. Impedance Biosensors: Applications to Sustainability and Remaining Technical Challenges. ACS Sustain Chem Eng. 2014 Jul 07; 2(7):1649-1655. Radhakrishnan R, Suni II, Bever CS, Hammock BD. PMID: 25068095; PMCID: PMC4105195.
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    383. Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. J Pain. 2014 Sep; 15(9):907-14. Wagner K, Yang J, Inceoglu B, Hammock BD. PMID: 24924124; PMCID: PMC4150748.
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    384. Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:21-9. Schebb NH, Ostermann AI, Yang J, Hammock BD, Hahn A, Schuchardt JP. PMID: 24880049; PMCID: PMC4247815.
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    385. GABAA receptor target of tetramethylenedisulfotetramine. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8607-12. Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone FC, Lightstone F, Yang J, Hammock BD, Casida JE. PMID: 24912155; PMCID: PMC4060666.
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    386. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8167-72. Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. PMID: 24843165; PMCID: PMC4050620.
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    387. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. J Lipid Res. 2014 06; 55(6):1131-8. Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. PMID: 24771868; PMCID: PMC4031944.
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    388. Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts. Drug Metab Dispos. 2014 Jul; 42(7):1098-102. Schebb NH, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH. PMID: 24733789; PMCID: PMC4170114.
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    389. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environ Res. 2014 May; 131:153-9. Trunnelle KJ, Bennett DH, Ahn KC, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD. PMID: 24721133; PMCID: PMC4152318.
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    390. Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis. PLoS One. 2014; 9(4):e94092. Li L, Li N, Pang W, Zhang X, Hammock BD, Ai D, Zhu Y. PMID: 24718617; PMCID: PMC3981766.
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    391. Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats. J Pharm Pharmacol. 2014 Sep; 66(9):1251-8. Shrestha A, Krishnamurthy PT, Thomas P, Hammock BD, Hwang SH. PMID: 24697323; PMCID: PMC4134728.
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    392. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 2014 Apr; 25(4):433-46. Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. PMID: 24525589; PMCID: PMC3947856.
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    393. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA. Prostaglandins Other Lipid Mediat. 2014 Jun; 109-111:23-31. Schuchardt JP, Schneider I, Willenberg I, Yang J, Hammock BD, Hahn A, Schebb NH. PMID: 24667634; PMCID: PMC4172375.
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    394. Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2014 May 01; 24(9):2193-7. Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD. PMID: 24685540; PMCID: PMC4019751.
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    395. Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors. Eur J Med Chem. 2014 Apr 22; 77:343-50. Kálai T, Altman R, Maezawa I, Balog M, Morisseau C, Petrlova J, Hammock BD, Jin LW, Trudell JR, Voss JC, Hideg K. PMID: 24657571; PMCID: PMC4065883.
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    396. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clin Exp Pharmacol Physiol. 2014 Mar; 41(3):227-37. Kujal P, Certíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Cervenka L. PMID: 24471737; PMCID: PMC4038339.
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    397. Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure. Am J Physiol Heart Circ Physiol. 2014 Apr 15; 306(8):H1146-53. Sun D, Cuevas AJ, Gotlinger K, Hwang SH, Hammock BD, Schwartzman ML, Huang A. PMID: 24561863; PMCID: PMC3989753.
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    398. Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase. Bioorg Med Chem. 2014 Feb 01; 22(3):1163-75. Kim IH, Lee IH, Nishiwaki H, Hammock BD, Nishi K. PMID: 24433964; PMCID: PMC4172381.
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    399. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. J Environ Sci Health B. 2014; 49(1):15-22. Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn KC, Gee SJ, Hammock BD. PMID: 24138464; PMCID: PMC4020914.
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    400. Development of a heterologous enzyme-linked immunosorbent assay for organophosphorus pesticides with phage-borne peptide. RSC Adv. 2014 Jan 01; 4(80):42445-42453. Hua X, Liu X, Shi H, Wang Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. PMID: 26290688; PMCID: PMC4539265.
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    401. Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostaglandins Leukot Essent Fatty Acids. 2014 Feb-Mar; 90(2-3):27-37. Schuchardt JP, Schmidt S, Kressel G, Willenberg I, Hammock BD, Hahn A, Schebb NH. PMID: 24411718; PMCID: PMC4130704.
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    402. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Prog Lipid Res. 2014 Jan; 53:108-23. Zhang G, Kodani S, Hammock BD. PMID: 24345640; PMCID: PMC3914417.
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    403. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One. 2013; 8(12):e80922. Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. PMID: 24349022; PMCID: PMC3862847.
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    404. Sequencing and de novo assembly of the transcriptome of the glassy-winged sharpshooter (Homalodisca vitripennis). PLoS One. 2013; 8(12):e81681. Nandety RS, Kamita SG, Hammock BD, Falk BW. PMID: 24339955; PMCID: PMC3858241.
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    405. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Res. 2013 Dec; 33(12):5261-5271. Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang GY. PMID: 24324059; PMCID: PMC4076172.
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    406. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. J Med Chem. 2013 Dec 12; 56(23):9457-70. Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH. PMID: 24261904; PMCID: PMC3938169.
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    407. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One. 2013; 8(10):e76575. Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. PMID: 24204640; PMCID: PMC3811983.
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    408. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int. 2013 Nov; 61:57-63. Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. PMID: 24096042; PMCID: PMC4059492.
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    409. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. J Exp Biol. 2013 Dec 15; 216(Pt 24):4615-25. Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D. PMID: 24072790; PMCID: PMC3851147.
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    410. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. Am J Physiol Heart Circ Physiol. 2013 Dec 01; 305(11):H1605-13. Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM. PMID: 24043255; PMCID: PMC3882464.
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    411. Effects of cadmium chloride on mouse inner medullary collecting duct cells. Interdiscip Toxicol. 2013 Sep; 6(3):157-8. Park EK, Mak SK, Hammock BD. PMID: 24678254; PMCID: PMC3967443.
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    412. Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2013 Sep; 62(3):285-97. Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. PMID: 23676336; PMCID: PMC3773051.
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    413. Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins Leukot Essent Fatty Acids. 2013 Oct; 89(5):351-8. Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ. PMID: 24055573; PMCID: PMC3897272.
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    414. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Anal Chem. 2013 Sep 03; 85(17):8298-303. Wang Y, Li P, Majkova Z, Bever CR, Kim HJ, Zhang Q, Dechant JE, Gee SJ, Hammock BD. PMID: 23965250; PMCID: PMC3787825.
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    415. Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola. J Lipid Res. 2013 Nov; 54(11):3215-9. Van Bogaert I, Zhang G, Yang J, Liu JY, Ye Y, Soetaert W, Hammock BD. PMID: 23966667; PMCID: PMC3793626.
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    416. Aging, estrogen loss and epoxyeicosatrienoic acids (EETs). PLoS One. 2013; 8(8):e70719. Lee AR, Pechenino AS, Dong H, Hammock BD, Knowlton AA. PMID: 23967089; PMCID: PMC3742755.
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    417. Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13528-33. Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. PMID: 23898174; PMCID: PMC3746918.
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    418. Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. Mol Nutr Food Res. 2013 Aug; 57(8):1378-89. Lundström SL, Yang J, Brannan JD, Haeggström JZ, Hammock BD, Nair P, O'Byrne P, Dahlén SE, Wheelock CE. PMID: 23824870; PMCID: PMC3943463.
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    419. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem. 2013 Jul 17; 61(28):6964-70. Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. PMID: 23767873; PMCID: PMC3723731.
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    420. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res. 2013 Aug; 57(8):1319-35. Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB. PMID: 23818328; PMCID: PMC3806310.
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    421. Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis. J Biol Chem. 2013 Aug 16; 288(33):23696-703. Frolov A, Dong H, Jiang M, Yang L, Cook EC, Matnani R, Hammock BD, Crofford LJ. PMID: 23814065; PMCID: PMC3745317.
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    422. Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol. PLoS One. 2013; 8(6):e65741. Boesten DM, Berger A, de Cock P, Dong H, Hammock BD, den Hartog GJ, Bast A. PMID: 23755276; PMCID: PMC3673924.
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    423. Characterization of Hovi-mEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis. Arch Insect Biochem Physiol. 2013 Aug; 83(4):171-9. Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety RS, Falk BW. PMID: 23704009; PMCID: PMC3846607.
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    424. Soluble epoxide hydrolase: gene structure, expression and deletion. Gene. 2013 Sep 10; 526(2):61-74. Harris TR, Hammock BD. PMID: 23701967; PMCID: PMC3733540.
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    425. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins Leukot Essent Fatty Acids. 2013 Jul; 89(1):19-29. Schuchardt JP, Schmidt S, Kressel G, Dong H, Willenberg I, Hammock BD, Hahn A, Schebb NH. PMID: 23694766; PMCID: PMC4057063.
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    426. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3732-7. Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. PMID: 23726028; PMCID: PMC3744640.
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    427. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3818-21. Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. PMID: 23684894; PMCID: PMC3703951.
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    428. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sci. 2013 Jun 21; 92(23):1145-50. Poli G, Corda E, Martino PA, Dall'ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. PMID: 23651659; PMCID: PMC3806320.
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    429. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem. 2013 May 17; 288(20):14189-14199. Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. PMID: 23576437; PMCID: PMC3656275.
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    430. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6530-5. Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 23553837; PMCID: PMC3631682.
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    431. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clin Exp Pharmacol Physiol. 2013 Apr; 40(4):273-81. Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. PMID: 23039246; PMCID: PMC3769696.
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    432. Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy. Br J Pharmacol. 2013 Apr; 168(8):1794-807. Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO. PMID: 23176298; PMCID: PMC3623051.
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    433. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5618-23. Sirish P, Li N, Liu JY, Lee KS, Hwang SH, Qiu H, Zhao C, Ma SM, López JE, Hammock BD, Chiamvimonvat N. PMID: 23493561; PMCID: PMC3619365.
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    434. Photonic crystal lab-on-a-chip for detecting staphylococcal enterotoxin B at low attomolar concentration. Anal Chem. 2013 Mar 19; 85(6):3104-9. Han JH, Kim HJ, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. PMID: 23418954; PMCID: PMC3608201.
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    435. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg. 2013 Jul; 40(4):440-8. Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. PMID: 23463912; PMCID: PMC3956586.
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    436. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem. 2013 Mar 13; 61(10):2426-33. Wang Y, Wang H, Li P, Zhang Q, Kim HJ, Gee SJ, Hammock BD. PMID: 23394544; PMCID: PMC3830680.
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    437. Carbon turnover in the water-soluble protein of the adult human lens. Mol Vis. 2013; 19:463-75. Stewart DN, Lango J, Nambiar KP, Falso MJ, FitzGerald PG, Rocke DM, Hammock BD, Buchholz BA. PMID: 23441119; PMCID: PMC3580966.
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    438. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. J Hypertens. 2013 Feb; 31(2):321-32. Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Cervenka L. PMID: 23307303; PMCID: PMC3773167.
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    439. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol Ther. 2013 Mar; 14(3):278-85. Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. PMID: 23298903; PMCID: PMC3595311.
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    440. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013 Mar 12; 48(4-5):619-27. Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. PMID: 23291046; PMCID: PMC3596469.
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    441. Rationally designed multitarget agents against inflammation and pain. Curr Med Chem. 2013; 20(13):1783-99. Hwang SH, Wecksler AT, Wagner K, Hammock BD. PMID: 23410172; PMCID: PMC4113248.
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    443. Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. J Toxicol Sci. 2013; 38(6):833-6. Yang J, Solaimani P, Dong H, Hammock B, Hankinson O. PMID: 24213002; PMCID: PMC4068614.
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    444. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. Eur J Pharmacol. 2013 Jan 30; 700(1-3):93-101. Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. PMID: 23276668; PMCID: PMC3578047.
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    445. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochem Mol Biol. 2013 Mar; 43(3):219-28. Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. PMID: 23276675; PMCID: PMC3577957.
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    446. Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout. Anal Chem. 2013 Jan 15; 85(2):1177-82. Vanrell L, Gonzalez-Techera A, Hammock BD, Gonzalez-Sapienza G. PMID: 23214940; PMCID: PMC3904493.
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    447. Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model. Prostaglandins Other Lipid Mediat. 2013 Jul-Aug; 104-105:42-8. Chen L, Fan C, Zhang Y, Bakri M, Dong H, Morisseau C, Maddipati KR, Luo P, Wang CY, Hammock BD, Wang MH. PMID: 23247129; PMCID: PMC4052893.
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    448. Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Anal Biochem. 2013 Mar 15; 434(2):259-68. Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. PMID: 23219719; PMCID: PMC3632402.
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    449. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Anal Biochem. 2013 Mar 01; 434(1):105-11. Morisseau C, Sahdeo S, Cortopassi G, Hammock BD. PMID: 23219563; PMCID: PMC3557602.
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    450. Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2013 Jan 15; 23(2):417-21. Pecic S, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD, Zhu Z, Rinderspacher A, Deng SX. PMID: 23237835; PMCID: PMC3541548.
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    451. Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Exp Biol Med (Maywood). 2012 Dec; 237(12):1402-12. Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD. PMID: 23354399; PMCID: PMC3613242.
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    452. Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations. Metabolomics. 2012 Dec; 8(6):1102-1113. Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. PMID: 23833568; PMCID: PMC3700377.
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    453. Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo. J Lipid Res. 2013 Feb; 54(2):436-47. Kundu S, Roome T, Bhattacharjee A, Carnevale KA, Yakubenko VP, Zhang R, Hwang SH, Hammock BD, Cathcart MK. PMID: 23160182; PMCID: PMC3588870.
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    454. Upregulation of soluble epoxide hydrolase in proximal tubular cells mediated proteinuria-induced renal damage. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F168-76. Wang Q, Pang W, Cui Z, Shi J, Liu Y, Liu B, Zhou Y, Guan Y, Hammock BD, Wang Y, Zhu Y. PMID: 23152298; PMCID: PMC3543623.
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    455. Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures. Chromatographia. 2013 Jan 01; 76(1-2):13-21. Falck D, Schebb NH, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM. PMID: 23526703; PMCID: PMC3601784.
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    456. Importance of membrane selection in the development of immunochromatographic assays for low-molecular weight compounds. Anal Chim Acta. 2012 Dec 13; 757:69-74. Lee JY, Kim YA, Kim MY, Lee YT, Hammock BD, Lee HS. PMID: 23206398; PMCID: PMC4113188.
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    457. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application in farmers and consumers. Anal Methods. 2012 Oct 24; 4(11):3772-3778. Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn KC, Gee SJ, Hammock BD. PMID: 23667388; PMCID: PMC3646417.
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    458. Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. J Immunol. 2012 Nov 15; 189(10):4960-9. Tamang DL, Pirzai W, Priebe GP, Traficante DC, Pier GB, Falck JR, Morisseau C, Hammock BD, McCormick BA, Gronert K, Hurley BP. PMID: 23045615; PMCID: PMC3490410.
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    459. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol. 2013; 53:37-58. Morisseau C, Hammock BD. PMID: 23020295; PMCID: PMC3578707.
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    460. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase. Anal Biochem. 2012 Dec 15; 431(2):77-83. Huang H, Yao H, Liu JY, Samra AI, Kamita SG, Cornel AJ, Hammock BD. PMID: 23000005; PMCID: PMC3489985.
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    461. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano. 2012 Oct 23; 6(10):8570-82. Han JH, Sudheendra L, Kim HJ, Gee SJ, Hammock BD, Kennedy IM. PMID: 22957818; PMCID: PMC3479307.
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    462. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron. 2013 Mar 15; 41:302-8. Han JH, Kim HJ, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. PMID: 23021853; PMCID: PMC3525773.
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    463. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kidney Blood Press Res. 2012; 35(6):595-607. Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Cervenka L. PMID: 22948718; PMCID: PMC3604982.
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    464. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. PMID: 22889812; PMCID: PMC3529644.
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    465. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14158-63. Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. PMID: 22891308; PMCID: PMC3435154.
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    466. Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats. Am J Physiol Heart Circ Physiol. 2012 Oct 01; 303(7):H853-62. Guglielmino K, Jackson K, Harris TR, Vu V, Dong H, Dutrow G, Evans JE, Graham J, Cummings BP, Havel PJ, Chiamvimonvat N, Despa S, Hammock BD, Despa F. PMID: 22865388; PMCID: PMC3469704.
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    467. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett. 2012 Sep 15; 22(18):5889-92. Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. PMID: 22901393; PMCID: PMC3432147.
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    468. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem. 2012 08 07; 84(15):6919. Kim HJ, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, González-Sapienza GG, Hammock BD. PMID: 22830304; PMCID: PMC3460544.
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