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Smartphone-integrated visual inspection for enhancing agricultural product quality and safety: a review. Crit Rev Food Sci Nutr. 2024 Sep 04; 1-23.
Xu L, Abd El-Aty AM, Li P, Li J, Zhao J, Lei X, Gao S, Zhao Y, She Y, Jin F, Wang J, Wang S, Zheng L, Hammock BD, Jin M. PMID: 39230393.
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Urinary metabolic profile and its predictive indexes after MSG consumption in rat. PLoS One. 2024; 19(9):e0309728.
Sukmak M, Kyaw TS, Nahok K, Sharma A, Silsirivanit A, Lert-Itthiporn W, Japrung D, Pinlaor S, Anutrakulchai S, Selmi C, Slupsky CM, Hammock BD, Cha'on U. PMID: 39226266; PMCID: PMC11371250.
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Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabolites in murine livers via lipidomic profiling. Sci Rep. 2024 08 19; 14(1):19135.
Sule RO, Morisseau C, Yang J, Hammock BD, Gomes AV. PMID: 39160161; PMCID: PMC11333623.
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Translation:
Animals
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Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain. Int J Mol Sci. 2024 Aug 14; 25(16).
Babkov D, Eliseeva N, Adzhienko K, Bagmetova V, Danilov D, McReynolds CB, Morisseau C, Hammock BD, Burmistrov V. PMID: 39201526.
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Translation:
Animals
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Versatility and stability of melamine foam-based biosensors (f-ELISA) using antibodies, nanobodies, and peptides as sensing probes. Talanta. 2024 Nov 01; 279:126634.
Pan B, He Q, Yu X, De Choch D, Lam KS, Hammock BD, Sun G. PMID: 39121553.
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In vivo -Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability. bioRxiv. 2024 Jul 24.
Nakane K, Morisseau C, Dowker-Key PD, Benitez G, Aguilan JT, Nagai E, Sidoli S, Hammock BD, Bettaieb A, Shinoda K, Kitamura S. PMID: 39211216; PMCID: PMC11361158.
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Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain. J Med Chem. 2024 Aug 08; 67(15):12887-12911.
Xu H, Chen Y, Tong H, Chen L, Morisseau C, Zhou Z, Zhuang J, Song C, Cai P, Liu Z, Hammock BD, Chen G. PMID: 39033411; PMCID: PMC11412156.
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Translation:
HumansAnimals
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Shark anti-idiotypic variable new antigen receptor specific for an alpaca nanobody: Exploration of a nontoxic substitute to ochratoxin A in immunoassay. J Hazard Mater. 2024 Sep 15; 477:135264.
Xie X, He Z, Sun Z, Zhang S, Cao H, Hammock BD, Liu X. PMID: 39032175.
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Translation:
Animals
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Correction: Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor. PLoS One. 2024; 19(7):e0307533.
Zhang C, Li W, Li X, Wan D, Mack S, Zhang J, Wagner K, Wang C, Tan B, Chen J, Wu CW, Tsuji K, Takeuchi M, Chen Z, Hammock BD, Pinkerton KE, Yang J. PMID: 39018323; PMCID: PMC11253952.
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PubMed Mentions: Fields:
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Evaluation of the Immune Response of Patulin by Proteomics. Biosensors (Basel). 2024 Jun 27; 14(7).
Wang F, Ma L, Wang Q, Hammock BD, Xiao G, Liu R. PMID: 39056598; PMCID: PMC11274796.
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Translation:
Animals
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Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations. Heliyon. 2024 Jun 15; 10(11):e32262.
Angelia J, Duong L, Yun F, Mesic A, Yuan C, Carr D, Gunari S, Hudson PK, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 38912512; PMCID: PMC11190605.
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Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS-CoV-2-infected mice. FASEB J. 2024 May 31; 38(10):e23692.
Edin ML, Gruzdev A, Graves JP, Lih FB, Morisseau C, Ward JM, Hammock BD, Bosio CM, Zeldin DC. PMID: 38786655; PMCID: PMC11141730.
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HumansAnimalsCells
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A new strategy to generate nanobodies for the coumaphos based on the synthesized nanobody libraries. Food Chem. 2024 Oct 15; 455:139684.
Fang R, Li Y, Liu F, Liang Y, Wang Y, Zhong G, Xu Z, Hammock BD, Wang H. PMID: 38833869; PMCID: PMC11239888.
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Translation:
CellsPHPublic Health
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A novel sustainable immunoassay for sensitive detection of atrazine based on the anti-idiotypic nanobody and recombinant full-length antibody. Chem Eng J. 2024 Jul 01; 491.
Zhao J, Li P, Abd El-Aty AM, Xu L, Lei X, Gao S, Li J, Zhao Y, She Y, Jin F, Wang J, Hammock BD, Jin M. PMID: 38882000; PMCID: PMC11173377.
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Fluorescent and Colorimetric Dual-Readout Immunochromatographic Assay for the Detection of Phenamacril Residues in Agricultural Products. J Agric Food Chem. 2024 May 15; 72(19):11241-11250.
Liu P, Jiang L, Zhao Y, Wang Y, Ye Y, Xue F, Hammock BD, Zhang C. PMID: 38709728.
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Translation:
AnimalsPHPublic Health
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Generation of a highly specific recombinant full-length antibody for detecting ethirimol in fruit and environmental water. J Hazard Mater. 2024 May 05; 469:134067.
Lei X, Li P, Abd El-Aty AM, Zhao J, Xu L, Gao S, Li J, Zhao Y, She Y, Jin F, Wang J, Zheng L, Hammock BD, Jin M. PMID: 38513441; PMCID: PMC11062638.
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HumansCells
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Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity. Insect Biochem Mol Biol. 2024 May; 168:104104.
Hossain Hrithik MT, Shahmohammadi N, Jin G, Lee DH, Singh N, Vik A, Hammock BD, Kim Y. PMID: 38494144; PMCID: PMC11062637.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Development of Shark Single Domain Antibodies Specific for Human α-Fetoprotein and the Multimerization Strategy in Serum Detection. Anal Chem. 2024 03 12; 96(10):4242-4250.
Wang Z, Xie X, He Z, Sun Z, Zhang Y, Mao F, Pei H, Zhang S, Hammock BD, Liu X. PMID: 38408370.
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HumansAnimals
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Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy. bioRxiv. 2024 Feb 19.
Panigrahy D, Kelly AG, Wang W, Yang J, Hwang SH, Gillespie M, Howard I, Bueno-Beti C, Asimaki A, Penna V, Lavine K, Edin ML, Zeldin DC, Hammock BD, Saffitz JE. PMID: 38463975; PMCID: PMC10925075.
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The Role of Autophagy in Human Uveal Melanoma and the Development of Potential Disease Biomarkers and Novel Therapeutic Paradigms. Biomedicines. 2024 Feb 19; 12(2).
Wang JZ, Paulus P, Niu Y, Zhu L, Morisseau C, Rawling T, Murray M, Hammock BD, Zhou F. PMID: 38398064; PMCID: PMC10886749.
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Colorimetric and surface-enhanced Raman scattering dual-mode lateral flow immunosensor using phage-displayed shark nanobody for the detection of crustacean allergen tropomyosin. J Hazard Mater. 2024 Apr 15; 468:133821.
Jiao S, Chen X, He Z, Wu L, Xie X, Sun Z, Zhang S, Cao H, Hammock BD, Liu X. PMID: 38377914.
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2 Fields:
Translation:
Cells
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Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2024 Feb 13; 121(7):e2314085121.
Kelly AG, Wang W, Rothenberger E, Yang J, Gilligan MM, Kipper FC, Attaya A, Gartung A, Hwang SH, Gillespie MJ, Bayer RL, Quinlivan KM, Torres KL, Huang S, Mitsiades N, Yang H, Hammock BD, Panigrahy D. PMID: 38330013; PMCID: PMC10873624.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Colorimetric and Reverse Fluorescence Dual-Signal Readout Immunochromatographic Assay for the Sensitive Determination of Sibutramine. ACS Omega. 2024 Feb 13; 9(6):7075-7084.
Gui Y, Zhao Y, Liu P, Wang Y, Mao X, Peng C, Hammock BD, Zhang C. PMID: 38371773; PMCID: PMC10870287.
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Modulating the sEH/EETs Axis Restrains Specialized Proresolving Mediator Impairment and Regulates T Cell Imbalance in Experimental Periodontitis. J Immunol. 2024 Feb 01; 212(3):433-445.
Abdalla HB, Puhl L, Rivas CA, Wu YC, Rojas P, Trindade-da-Silva CA, Hammock BD, Maddipati KR, Soares MQS, Clemente-Napimoga JT, Kantarci A, Napimoga MH, Van Dyke TE. PMID: 38117781; PMCID: PMC10866374.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Establishment of an indirect competitive immunoassay for the detection of dicamba based on a highly specific nanobody. Sci Total Environ. 2024 Mar 20; 917:170567.
Wang Y, Zhou H, Fu Y, Wang Z, Gao Q, Yang D, Kang J, Chen L, An Z, Hammock BD, Zhang J, Huo J. PMID: 38296098; PMCID: PMC10936929.
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PubMed Mentions:
1 Fields:
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Immunoassays and Emerging Analytical Techniques of Fipronil and its Metabolites for Food Safety: A Review. J Agric Food Chem. 2024 Jan 31; 72(4):2059-2076.
Li P, Abd El-Aty AM, Jiang H, Shen J, Wang Z, Wen K, Li J, Wang S, Wang J, Hammock BD, Jin M. PMID: 38252458.
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Translation:
HumansAnimals
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Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality. J Med Chem. 2024 02 08; 67(3):2095-2117.
Chen Y, Sun J, Tong H, Wang J, Cao R, Xu H, Chen L, Morisseau C, Zhang M, Shi Y, Han C, Zhuang J, Jing Y, Liu Z, Hammock BD, Chen G. PMID: 38236416; PMCID: PMC11308793.
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Translation:
Animals
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Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Biomed Pharmacother. 2024 Feb; 171:116127.
Naeem Z, Zukunft S, Huard A, Hu J, Hammock BD, Weigert A, Frömel T, Fleming I. PMID: 38198951; PMCID: PMC10857809.
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Translation:
AnimalsCells
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Development of an immunoassay based on a specific antibody for the detection of diphenyl ether herbicide fomesafen. Sci Total Environ. 2024 Mar 01; 914:169858.
Gao Q, Chen L, An Z, Wang Y, Yang D, Wang Z, Kang J, Barnych B, Hammock BD, Huo J, Zhang J. PMID: 38190900; PMCID: PMC10871040.
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PubMed Mentions: Fields:
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Lateral Flow Immunochromatographic Assay for Competitive Detection of Crustacean Allergen Tropomyosin Using Phage-Displayed Shark Single-Domain Antibody. J Agric Food Chem. 2024 Jan 24; 72(3):1811-1821.
Jiao S, Xie X, He Z, Sun Z, Wang Z, Zhang S, Cao H, Hammock BD, Liu X. PMID: 38166198.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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COX-2/sEH-Mediated Macrophage Activation Is a Target for Pulmonary Protection in Mouse Models of Chronic Obstructive Pulmonary Disease. Lab Invest. 2024 03; 104(3):100319.
Duan JX, Guan XX, Cheng W, Deng DD, Chen P, Liu C, Zhou Y, Hammock BD, Yang HH. PMID: 38158123.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Determinants of Meal-Induced Changes in Circulating FFA Epoxides, Diols, and Diol-to-Epoxide Ratios as Indices of Soluble Epoxide Hydrolase Activity. Int J Mol Sci. 2023 Dec 11; 24(24).
Oh YT, Yang J, Stefanovski D, Hammock B, Youn JH. PMID: 38139180; PMCID: PMC10743433.
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Translation:
HumansAnimals
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HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver. Front Endocrinol (Lausanne). 2023; 14:1266527.
Deans JR, Deol P, Titova N, Radi SH, Vuong LM, Evans JR, Pan S, Fahrmann J, Yang J, Hammock BD, Fiehn O, Fekry B, Eckel-Mahan K, Sladek FM. PMID: 38111711; PMCID: PMC10726135.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Development of a sensitive direct competitive chemiluminescent enzyme immunoassay for gentamicin based on the construction of a specific single-chain variable fragment-alkaline phosphatase fusion protein. Microchem J. 2024 Feb; 197.
Deng W, Wang D, Dai P, Hong Y, Xiong J, Duan L, Lu R, Wan J, Du H, Hammock BD, Yang W. PMID: 38283367; PMCID: PMC10810264.
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Role of soluble epoxide hydrolase in the abnormal activation of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Clin Immunol. 2023 12; 257:109850.
Pu Y, Cheng R, Zhang Q, Huang T, Lu C, Tang Z, Zhong Y, Wu L, Hammock BD, Hashimoto K, Luo Y, Liu Y. PMID: 38013165; PMCID: PMC10872286.
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HumansAnimalsCells
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Illuminating the path: aggregation-induced emission for food contaminants detection. Crit Rev Food Sci Nutr. 2023 Nov 20; 1-28.
Chen X, He Z, Huang X, Sun Z, Cao H, Wu L, Zhang S, Hammock BD, Liu X. PMID: 37983139.
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Eicosanoid profiles in an arthritis model: Effects of a soluble epoxide hydrolase inhibitor. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 03; 1869(2):159432.
Trindade-da-Silva CA, Yang J, Fonseca F, Pham H, Napimoga MH, Abdalla HB, Aver G, De Oliveira MJA, Hammock BD, Clemente-Napimoga JT. PMID: 37984607; PMCID: PMC10842726.
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Translation:
Humans
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Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy. J Enzyme Inhib Med Chem. 2023 Dec; 38(1):2274797.
Burmistrov VV, Morisseau C, Danilov DV, Gladkikh BP, D'yachenko VS, Zefirov NA, Zefirova ON, Butov GM, Hammock BD. PMID: 37975322; PMCID: PMC11003477.
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HumansCells
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Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water. Anal Bioanal Chem. 2024 Jan; 416(1):141-149.
Wu S, Tian J, Xue X, Ma F, Li QX, Morisseau C, Hammock BD, Xu T. PMID: 37934249; PMCID: PMC10829939.
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Cells
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Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease. Am J Pathol. 2024 01; 194(1):71-84.
Warner JB, Hardesty JE, Song YL, Floyd AT, Deng Z, Jebet A, He L, Zhang X, McClain CJ, Hammock BD, Warner DR, Kirpich IA. PMID: 37925018; PMCID: PMC10768534.
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Translation:
AnimalsCells
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Dynamics of temporal immune responses in nonhuman primates and humans immunized with COVID-19 vaccines. PLoS One. 2023; 18(10):e0287377.
Ravindran R, Kang H, McReynolds C, Sanghar GK, Chang WLW, Ramasamy S, Kolloli A, Kumar R, Subbian S, Hammock BD, Hartigan-O'Connor DJ, Ikram A, Haczku A, Khan IH. PMID: 37856429; PMCID: PMC10586671.
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Translation:
HumansAnimalsCellsPHPublic Health
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Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress. Biomed Pharmacother. 2023 Dec; 168:115667.
Peyman M, Barroso E, Turcu AL, Estrany F, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, Palomer X, Galdeano C, Vázquez S, Vázquez-Carrera M. PMID: 37826940; PMCID: PMC10786198.
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HumansAnimals
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Generating Monoclonal Antibodies against Buprofezin and Developing Immunoassays for Its Residue Detection in Tea Samples. J Agric Food Chem. 2023 Oct 18; 71(41):14967-14978.
Xu L, Abd El Aty AM, Cao Z, Lei X, Zhao J, Li J, Gao S, Zhao Y, She Y, Jin F, Wang J, Jin M, Hammock BD. PMID: 37803933; PMCID: PMC10807744.
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Translation:
Humans
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The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase. Int J Mol Sci. 2023 Sep 28; 24(19).
He Q, McCoy MR, Qi M, Morisseau C, Yang H, Xu C, Shey R, Goodman MC, Zhao S, Hammock BD. PMID: 37834144; PMCID: PMC10572367.
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Humans
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A dendritic/tumor fusion cell vaccine enhances efficacy of nanobody-based CAR-T cells against solid tumor. Theranostics. 2023; 13(14):5099-5113.
Sun S, Ding Z, Gao L, Hammock BD, Huang X, Xu ZP, Wang X, Cheng Q, Mo F, Shi W, Xie S, Liu A, Li H, Yang X, Lu X. PMID: 37771772; PMCID: PMC10526666.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy. Signal Transduct Target Ther. 2023 09 04; 8(1):328.
Yang XM, Lin XD, Shi W, Xie SX, Huang XN, Yin SH, Jiang XB, Hammock BD, Xu ZP, Lu XL. PMID: 37661200; PMCID: PMC10475457.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Competitive ratiometric fluorescent lateral flow immunoassay based on dual emission signal for sensitive detection of chlorothalonil. Food Chem. 2024 Feb 01; 433:137200.
Fang X, Liu T, Xue C, Xue G, Wu M, Liu P, Hammock BD, Lai W, Peng J, Zhang C. PMID: 37678117; PMCID: PMC10829940.
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PubMed Mentions: Fields:
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Development of a Biotinylated Nanobody-Based Gold Nanoparticle Immunochromatographic Assay for the Detection of Procymidone in Crops. J Agric Food Chem. 2023 Sep 06; 71(35):13137-13146.
Liu ML, He XT, Xu ZL, Deng H, Shen YD, Luo L, Shen X, Chen ZJ, Hammock B, Wang H. PMID: 37611148; PMCID: PMC10849196.
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Translation:
Animals
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Design of an Antigen-Triggered Nanobody-Based Fluorescence Probe for PET Immunoassay to Detect Quinalphos in Food Samples. Anal Chem. 2023 08 22; 95(33):12321-12328.
Liang YF, Li JD, Fang RY, Xu ZL, Luo L, Chen ZJ, Yang JY, Shen YD, Ueda H, Hammock B, Wang H. PMID: 37527540.
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2 Fields:
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Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and H-151 downregulate inflammatory cytokines in the cGAS-STING pathway. FASEB J. 2023 08; 37(8):e23068.
Zamiri K, Kesari S, Paul K, Hwang SH, Hammock B, Kaczor-Urbanowicz KE, Urbanowicz A, Gao L, Whitelegge J, Fiala M. PMID: 37436778; PMCID: PMC10619685.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins during their inducible expression in Escherichia coli. Anal Bioanal Chem. 2023 Sep; 415(23):5563-5574.
Yin Z, He Q, Yang H, Morisseau C, El-Sheikh EA, Li D, Hammock BD. PMID: 37505234; PMCID: PMC10473979.
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Translation:
Cells
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A bispecific nanobody with high sensitivity/efficiency for simultaneous determination of carbaryl and its metabolite 1-naphthol in the soil and rice samples. Environ Pollut. 2023 Oct 15; 335:122265.
Liu ML, Chen ZJ, Huang XQ, Wang H, Zhao JL, Shen YD, Luo L, Wen XW, Hammock B, Xu ZL. PMID: 37517641; PMCID: PMC10529271.
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2 Fields:
Translation:
Animals
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Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis. bioRxiv. 2023 Jul 11.
Kim D, Horimatsu T, Ogbi M, Goo B, Shi H, Veerapaneni P, Chouhaita R, Moses M, Prasad R, Benson TW, Harb R, Aboud G, Seller H, Haigh S, Fulton DJ, Csányi G, Huo Y, Long X, Coffey P, Lee R, Guha A, Zeldin D, Hwang SH, Hammock BD, Weintraub NL, Kim HW. PMID: 37503031; PMCID: PMC10369876.
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Structural Insights into the Stability and Recognition Mechanism of the Antiquinalphos Nanobody for the Detection of Quinalphos in Foods. Anal Chem. 2023 08 01; 95(30):11306-11315.
Li JD, Wu GP, Li LH, Wang LT, Liang YF, Fang RY, Zhang QL, Xie LL, Shen X, Shen YD, Xu ZL, Wang H, Hammock BD. PMID: 37428097; PMCID: PMC10829938.
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Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity. bioRxiv. 2023 Jul 07.
Hrithrik TH, Lee DH, Singh N, Vik A, Hammock BD, Kim Y. PMID: 37461499; PMCID: PMC10350063.
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Precise isolation and structural origin of an ultra-specific nanobody against chemical compound. J Hazard Mater. 2023 09 15; 458:131958.
Yang H, Vasylieva N, Wang J, Li Z, Duan W, Chen S, Wen K, Meng H, Yu X, Shen J, Hammock BD, Wang Z. PMID: 37429192; PMCID: PMC10686526.
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PubMed Mentions:
1 Fields:
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Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity. Int J Mol Sci. 2023 Jun 28; 24(13).
Oh YT, Yang J, Morisseau C, He Q, Hammock B, Youn JH. PMID: 37445935; PMCID: PMC10341844.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis. Front Immunol. 2023; 14:1173544.
Steffan BN, Calise D, Park SC, Niu M, Yang J, Hammock BD, Jones M, Steele C, Keller NP. PMID: 37435068; PMCID: PMC10331294.
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Animals
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Enhancement of the liver's neuroprotective role ameliorates traumatic brain injury pathology. Proc Natl Acad Sci U S A. 2023 06 27; 120(26):e2301360120.
Dai Y, Dong J, Wu Y, Zhu M, Xiong W, Li H, Zhao Y, Hammock BD, Zhu X. PMID: 37339206; PMCID: PMC10293829.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury. J Hazard Mater. 2023 09 15; 458:131890.
Zhang J, Zhang WH, Morisseau C, Zhang M, Dong HJ, Zhu QM, Huo XK, Sun CP, Hammock BD, Ma XC. PMID: 37406527; PMCID: PMC10699546.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity. Int J Mol Sci. 2023 Jun 09; 24(12).
Wang W, Wang Y, Wagner KM, Lee RD, Hwang SH, Morisseau C, Wulff H, Hammock BD. PMID: 37373086; PMCID: PMC10298596.
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Animals
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Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice. Front Physiol. 2023; 14:1185744.
Pan S, Karey E, Nieves-Cintron M, Chen YJ, Hwang SH, Hammock BD, Pinkerton KE, Chen CY. PMID: 37362438; PMCID: PMC10285070.
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An Integrated Approach to Improve the Assay Performance of Quantum Dot-Based Lateral Flow Immunoassays by Using Silver Deposition. Microchem J. 2023 Sep; 192.
Wang Y, Liu P, Ye Y, Hammock BD, Zhang C. PMID: 38344211; PMCID: PMC10857874.
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Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act as biomarkers and mechanisms for disease progression. Pharmacol Ther. 2023 08; 248:108454.
McReynolds C, Hammock B, Morisseau C. PMID: 37268114; PMCID: PMC10529401.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomized to a Low Linoleic Acid Diet with or without Added Omega-3 Fatty Acids. Metabolites. 2023 May 25; 13(6).
Shen Q, Yang J, Zamora D, Horowitz M, Faurot KR, MacIntosh BA, Mann JD, Hammock BD, Ramsden CE, Taha AY. PMID: 37367848; PMCID: PMC10304617.
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PubMed Mentions:
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Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis. Int Immunopharmacol. 2023 Jul; 120:110320.
Tarkany Basting R, Henrique Napimoga M, Antônio Trindade Silva C, Ballassini Abdalla H, Campos Durso B, Henrique Barboza Martins L, de Abreu Cavalcanti H, Hammock BD, Trindade Clemente-Napimoga J. PMID: 37230034; PMCID: PMC10631565.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA. J Pharm Anal. 2023 Sep; 13(9):1013-1023.
Yang H, Qi M, He Q, Hwang SH, Yang J, McCoy M, Morisseau C, Zhao S, Hammock BD. PMID: 37842656; PMCID: PMC10568103.
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PubMed Mentions:
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Residue Analysis and Risk Exposure Assessment of Multiple Pesticides in Tomato and Strawberry and Their Products from Markets. Foods. 2023 May 10; 12(10).
El-Sheikh EA, Li D, Hamed I, Ashour MB, Hammock BD. PMID: 37238754; PMCID: PMC10217756.
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PubMed Mentions:
6
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Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits. J Chem Inf Model. 2023 05 22; 63(10):3209-3225.
Vázquez J, Ginex T, Herrero A, Morisseau C, Hammock BD, Luque FJ. PMID: 37141492; PMCID: PMC10207366.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice. Biochem Biophys Res Commun. 2023 07 30; 667:64-72.
Kulkarni R, Mehta R, Goswami SK, Hammock BD, Morisseau C, Hwang SH, Mallappa O, Azeemuddin MM, Rafiq M, S N M. PMID: 37209564; PMCID: PMC10849156.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Mix-and-Read Nanobody-Based Sandwich Homogeneous Split-Luciferase Assay for the Rapid Detection of Human Soluble Epoxide Hydrolase. Anal Chem. 2023 04 11; 95(14):6038-6045.
He Q, McCoy MR, Yang H, Lin M, Cui X, Zhao S, Morisseau C, Li D, Hammock BD. PMID: 36972550; PMCID: PMC10335774.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction. ACS Chem Biol. 2023 04 21; 18(4):884-896.
Wang Y, Morisseau C, Takamura A, Wan D, Li D, Sidoli S, Yang J, Wolan DW, Hammock BD, Kitamura S. PMID: 36947831; PMCID: PMC10586715.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Development of a Genetically Encoded Magnetic Platform in Magnetospirillum gryphiswaldense MSR-1 for Downstream Processing of Protein Expression System. Res Sq. 2023 Mar 13.
Wu S, Tian J, Xue X, Tang Z, Huang Z, Hammock BD, Morisseau C, Li QX, Xu T. PMID: 36993437; PMCID: PMC10055543.
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PubMed Mentions:
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Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon. Int J Mol Sci. 2023 Feb 26; 24(5).
Wang W, Wagner KM, Wang Y, Singh N, Yang J, He Q, Morisseau C, Hammock BD. PMID: 36901999; PMCID: PMC10003560.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury. ACS Cent Sci. 2023 Mar 22; 9(3):440-456.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC. PMID: 36968547; PMCID: PMC10037491.
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PubMed Mentions:
8
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Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10. EMBO J. 2023 03 15; 42(6):e112202.
Richter FC, Friedrich M, Kampschulte N, Piletic K, Alsaleh G, Zummach R, Hecker J, Pohin M, Ilott N, Guschina I, Wideman SK, Johnson E, Borsa M, Hahn P, Morriseau C, Hammock BD, Schipper HS, Edwards CM, Zechner R, Siegmund B, Weidinger C, Schebb NH, Powrie F, Simon AK. PMID: 36795015; PMCID: PMC10015370.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Production of a Monoclonal Antibody for the Detection of Forchlorfenuron: Application in an Indirect Enzyme-Linked Immunosorbent Assay and Immunochromatographic Strip. Biosensors (Basel). 2023 Feb 07; 13(2).
Lei X, Abd El-Aty AM, Xu L, Zhao J, Li J, Gao S, Zhao Y, She Y, Jin F, Wang J, Zheng L, Jin M, Hammock BD. PMID: 36832005; PMCID: PMC9954037.
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PubMed Mentions:
1 Fields:
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Competitive fluorescent immunosensor based on catalytic hairpin self-assembly for multiresidue detection of organophosphate pesticides in agricultural products. Food Chem. 2023 Jul 01; 413:135607.
Wang Y, Abd El-Aty AM, Wang S, Cui X, Zhao J, Lei X, Xu L, She Y, Jin F, Eun JB, Shim JH, Wang J, Jin M, Hammock BD. PMID: 36773354; PMCID: PMC10013200.
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PubMed Mentions:
1 Fields:
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The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling. J Transl Med. 2023 02 02; 21(1):71.
Luo A, Wu Z, Li S, McReynolds CB, Wang D, Liu H, Huang C, He T, Zhang X, Wang Y, Liu C, Hammock BD, Hashimoto K, Yang C. PMID: 36732752; PMCID: PMC9896784.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Soluble epoxide hydrolase inhibition enhances production of specialized pro-resolving lipid mediator and promotes macrophage plasticity. Br J Pharmacol. 2023 06; 180(12):1597-1615.
Abdalla HB, Alvarez C, Wu YC, Rojas P, Hammock BD, Maddipati KR, Trindade-da-Silva CA, Soares MQS, Clemente-Napimoga JT, Kantarci A, Napimoga MH, Van Dyke TE. PMID: 36508312; PMCID: PMC10175184.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases. J Med Chem. 2023 02 23; 66(4):2979-3009.
Chen Y, Chen L, Xu H, Cao R, Morisseau C, Zhang M, Shi Y, Hammock BD, Wang J, Zhuang J, Liu Z, Chen G. PMID: 36689364; PMCID: PMC9974930.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Inhibition of soluble epoxide hydrolase reduces paraquat neurotoxicity in rodents. Environ Toxicol Pharmacol. 2023 Mar; 98:104070.
Atone J, Wagner K, Koike S, Yang J, Hwang SH, Hammock BD. PMID: 36682504; PMCID: PMC9992278.
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PubMed Mentions: Fields:
Translation:
Animals
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Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors. J Fluor Chem. 2023 Feb; 266.
Burmistrov VV, Morisseau C, Shkineva TK, Danilov DV, Gladkikh B, Butov GM, Fayzullin RR, Dutova TY, Hammock BD, Dalinger IL. PMID: 37638129; PMCID: PMC10457016.
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PubMed Mentions:
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Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain. Front Pain Res (Lausanne). 2022; 3:1100524.
Takeshita AA, Hammock BD, Wagner KM. PMID: 36700145; PMCID: PMC9868926.
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PubMed Mentions:
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Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer. Oncogene. 2023 02; 42(9):693-707.
Yang JC, Xu P, Ning S, Wasielewski LJ, Adomat H, Hwang SH, Morisseau C, Gleave M, Corey E, Gao AC, Lara PN, Evans CP, Hammock BD, Liu C. PMID: 36596844; PMCID: PMC9975039.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Polyunsaturated Fatty Acids Mend Macrophage Transcriptome, Glycome, and Phenotype in the Patients with Neurodegenerative Diseases, Including Alzheimer's Disease. J Alzheimers Dis. 2023; 91(1):245-261.
Dover M, Moseley T, Biskaduros A, Paulchakrabarti M, Hwang SH, Hammock B, Choudhury B, Kaczor-Urbanowicz KE, Urbanowicz A, Morselli M, Dang J, Pellegrini M, Paul K, Bentolila LA, Fiala M. PMID: 36373322; PMCID: PMC9881025.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury. Int J Biol Sci. 2023; 19(1):294-310.
Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC. PMID: 36594097; PMCID: PMC9760444.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Computational design of peptides to target NaV1.7 channel with high potency and selectivity for the treatment of pain. Elife. 2022 12 28; 11.
Nguyen PT, Nguyen HM, Wagner KM, Stewart RG, Singh V, Thapa P, Chen YJ, Lillya MW, Ton AT, Kondo R, Ghetti A, Pennington MW, Hammock B, Griffith TN, Sack JT, Wulff H, Yarov-Yarovoy V. PMID: 36576241; PMCID: PMC9831606.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Obtaining a Monoclonal Antibody against a Novel Prometryn-Like Hapten and Characterization of Its Selectivity for Triazine Herbicides. Biosensors (Basel). 2022 Dec 25; 13(1).
Xu L, Abd El-Aty AM, Zhao J, Lei X, Zhang X, Zhao Y, Cui X, She Y, Jin F, Wang J, Jin M, Hammock BD. PMID: 36671858; PMCID: PMC9855386.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior. Prostaglandins Other Lipid Mediat. 2023 02; 164:106702.
Angelia J, Weng X, Solomatov A, Chin C, Fernandez A, Hudson PK, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 36529320; PMCID: PMC9879382.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner. Ecotoxicol Environ Saf. 2023 Jan 01; 249:114417.
Wang W, Wang Y, Yang J, Wagner KM, Hwang SH, Cheng J, Singh N, Edwards P, Morisseau C, Zhang G, Panigrahy D, Hammock BD. PMID: 36525946; PMCID: PMC9879385.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip. Anal Chem. 2022 12 20; 94(50):17567-17576.
Song J, He K, Xing B, Pei Y, Wang D, Wang Y, Li S, Li J, Huan W, Zhang Y, Hammock BD. PMID: 36458677; PMCID: PMC9942939.
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PubMed Mentions:
1 Fields:
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Pesticide Residues in Vegetables and Fruits from Farmer Markets and Associated Dietary Risks. Molecules. 2022 Nov 21; 27(22).
El-Sheikh EA, Ramadan MM, El-Sobki AE, Shalaby AA, McCoy MR, Hamed IA, Ashour MB, Hammock BD. PMID: 36432173; PMCID: PMC9695969.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsPHPublic Health
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Ureas derived from camphor and fenchone reveal enantiomeric preference of human soluble epoxide hydrolase. Results Chem. 2022 Jan; 4.
Burmistrov V, Morisseau C, Pitushkin D, Fayzullin RR, Karlov D, Vernigora A, Kuznetsov Y, Abbas SMH, Butov GM, Hammock BD. PMID: 37601415; PMCID: PMC10438916.
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PubMed Mentions:
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Development of immunoassay based on a specific antibody for sensitive detection of nicosulfuron in environment. Sci Total Environ. 2023 Feb 10; 859(Pt 1):160247.
Gao Q, Huo J, Chen L, Yang D, Zhang W, Jia B, Xu X, Barnych B, Zhang J, Hammock BD. PMID: 36400293; PMCID: PMC10042444.
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PubMed Mentions: Fields:
-
Screening, Expression, and Identification of Nanobody against SARS-CoV-2 Spike Protein. Cells. 2022 10 24; 11(21).
Su Q, Shi W, Huang X, Wan Y, Li G, Xing B, Xu ZP, Liu H, Hammock BD, Yang X, Yin S, Lu X. PMID: 36359751; PMCID: PMC9656363.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Reply to Chao et al. Comment on "Nahok et al. Monosodium Glutamate Induces Changes in Hepatic and Renal Metabolic Profiles and Gut Microbiome of Wistar Rats. Nutrients 2021, 13, 1865". Nutrients. 2022 Oct 19; 14(20).
Nahok K, Selmi C, Sukmak M, Phetcharaburanin J, Li JV, Silsirivanit A, Thanan R, Sharma A, Anutrakulchai S, Hammock BD, Cha'on U. PMID: 36297071; PMCID: PMC9611631.
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PubMed Mentions: Fields:
Translation:
Animals
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Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors. J Med Chem. 2022 10 27; 65(20):13660-13680.
Codony S, Entrena JM, Calvó-Tusell C, Jora B, González-Cano R, Osuna S, Corpas R, Morisseau C, Pérez B, Barniol-Xicota M, Griñán-Ferré C, Pérez C, Rodríguez-Franco MI, Martínez AL, Loza MI, Pallàs M, Verhelst SHL, Sanfeliu C, Feixas F, Hammock BD, Brea J, Cobos EJ, Vázquez S. PMID: 36222708; PMCID: PMC9620236.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Recent Advances in Rapid Detection Techniques for Pesticide Residue: A Review. J Agric Food Chem. 2022 Oct 19; 70(41):13093-13117.
Xu L, Abd El-Aty AM, Eun JB, Shim JH, Zhao J, Lei X, Gao S, She Y, Jin F, Wang J, Jin M, Hammock BD. PMID: 36210513; PMCID: PMC10584040.
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PubMed Mentions:
10 Fields:
Translation:
PHPublic Health
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Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women. Int J Mol Sci. 2022 Oct 05; 23(19).
Nguyen N, Morisseau C, Li D, Yang J, Lam E, Woodside DB, Hammock BD, Shih PB. PMID: 36233100; PMCID: PMC9569757.
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PubMed Mentions: Fields:
Translation:
Humans
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A highly sensitive electrochemical immunosensor based on electrospun nanocomposite for the detection of parathion. Food Chem. 2023 Mar 15; 404(Pt A):134371.
Yin WJ, Zhang JX, Wang H, Wang Y, Zeng X, Xu ZL, Yang JY, Xiao ZL, Hammock BD, Wen P. PMID: 36244073.
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PubMed Mentions:
3 Fields:
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Monosodium glutamate consumption reduces the renal excretion of trimethylamine N-oxide and the abundance of Akkermansia muciniphila in the gut. Biochem Biophys Res Commun. 2022 11 19; 630:158-166.
Kyaw TS, Sukmak M, Nahok K, Sharma A, Silsirivanit A, Lert-Itthiporn W, Sansurin N, Senthong V, Anutrakulchai S, Sangkhamanon S, Pinlaor S, Selmi C, Hammock BD, Cha'on U. PMID: 36155062; PMCID: PMC9851609.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety. Int J Mol Sci. 2022 Sep 14; 23(18).
Burmistrov V, Morisseau C, Babkov DA, Golubeva T, Pitushkin D, Sokolova EV, Vasipov V, Kuznetsov Y, Bazhenov SV, Novoyatlova US, Bondarev NA, Manukhov IV, Osipova V, Berberova N, Spasov AA, Butov GM, Hammock BD. PMID: 36142611; PMCID: PMC9501280.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Production of high affinity monoclonal antibody and development of indirect competitive chemiluminescence enzyme immunoassay for gentamicin residue in animal tissues. Food Chem. 2023 Jan 30; 400:134067.
Dai P, Zhang Y, Hong Y, Xiong J, Du H, Duan L, Wang D, Wang Y, Deng W, Hammock BD, Yang W. PMID: 36084594.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Generation of bioluminescent enzyme immunoassay for ferritin by single-chain variable fragment and its NanoLuc luciferase fusion. Anal Bioanal Chem. 2022 Sep; 414(23):6939-6946.
He Q, Yang L, Lin M, Yang H, Cui X, McCoy MR, Hammock BD, Fang Y, Zhao S. PMID: 35945290; PMCID: PMC9531656.
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PubMed Mentions: Fields:
Translation:
Cells
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Detection of Acrylamide in Foodstuffs by Nanobody-Based Immunoassays. J Agric Food Chem. 2022 Jul 27; 70(29):9179-9186.
Liang Y, Zeng Y, Luo L, Xu Z, Shen Y, Wang H, Hammock BD. PMID: 35819336; PMCID: PMC10111249.
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PubMed Mentions:
5 Fields:
Translation:
PHPublic Health
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Using a quantum dot bead-based lateral flow immunoassay to broadly detect the adulteration of PDE-5 inhibitors in functional foods. Anal Methods. 2022 07 07; 14(26):2586-2595.
Song M, Wu Q, Liu B, Li P, Jiang L, Wang Y, Dong S, Xiong Y, Hammock BD, Zhang C. PMID: 35723455; PMCID: PMC11257028.
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PubMed Mentions: Fields:
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The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms. Prostaglandins Other Lipid Mediat. 2022 10; 162:106662.
Matsumoto N, Singh N, Lee KS, Barnych B, Morisseau C, Hammock BD. PMID: 35779854; PMCID: PMC9530012.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Design and Characterization of a Novel Hapten and Preparation of Monoclonal Antibody for Detecting Atrazine. Foods. 2022 Jun 13; 11(12).
Xu L, Abd El-Aty AM, Shim JH, Eun JB, Lei X, Zhao J, Zhang X, Cui X, She Y, Jin F, Zheng L, Wang J, Jin M, Hammock BD. PMID: 35741925; PMCID: PMC9223028.
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PubMed Mentions:
5
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Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. Pflugers Arch. 2022 09; 474(9):1021-1035.
Naeem Z, Zukunft S, Günther S, Liebner S, Weigert A, Hammock BD, Frömel T, Fleming I. PMID: 35648219; PMCID: PMC9393123.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Omega-6 Polyunsaturated Fatty Acids Enhance Tumor Aggressiveness in Experimental Lung Cancer Model: Important Role of Oxylipins. Int J Mol Sci. 2022 May 31; 23(11).
Montecillo-Aguado M, Tirado-Rodriguez B, Antonio-Andres G, Morales-Martinez M, Tong Z, Yang J, Hammock BD, Hernandez-Pando R, Huerta-Yepez S. PMID: 35682855; PMCID: PMC9181584.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Correction to: A competitive immunoassay for detecting triazophos based on fluorescent catalytic hairpin self-assembly. Mikrochim Acta. 2022 May 24; 189(6):227.
Wang Y, Abd El-Aty AM, Chen G, Jia H, Cui X, Xu L, Cao Z, She Y, Jin F, Zhang Y, Hacimuftuoglu A, Lamu S, Wang J, Zheng L, Jin M, Hammock BD. PMID: 35608688; PMCID: PMC10699551.
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PubMed Mentions: Fields:
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A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides based on fluorescence anti-quenching. J Pharm Anal. 2022 Aug; 12(4):637-644.
Xu L, Zhang X, Abd El-Aty AM, Wang Y, Cao Z, Jia H, Salvador JP, Hacimuftuoglu A, Cui X, Zhang Y, Wang K, She Y, Jin F, Zheng L, Pujia B, Wang J, Jin M, Hammock BD. PMID: 36105157; PMCID: PMC9463527.
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PubMed Mentions:
3
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Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary tracer. Anal Methods. 2022 05 13; 14(18):1810-1819.
Singh N, Li D, McReynolds CB, Morisseau C, Hammock BD. PMID: 35481804; PMCID: PMC9116231.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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New Approach to Generate Ratiometric Signals on Immunochromatographic Strips for Small Molecules. Anal Chem. 2022 05 24; 94(20):7358-7367.
Chen H, Ding Y, Li J, Huang L, González-Sapienza G, Hammock BD, Wang M, Hua X. PMID: 35536756.
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PubMed Mentions:
2 Fields:
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Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor. PLoS One. 2022; 17(4):e0266608.
Zhang C, Li W, Li X, Wan D, Mack S, Zhang J, Wagner K, Wang C, Tan B, Chen J, Wu CW, Tsuji K, Takeuchi M, Chen Z, Hammock BD, Pinkerton KE, Yang J. PMID: 35443010; PMCID: PMC9020733.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Production and Characterization of Biotinylated Anti-fenitrothion Nanobodies and Development of Sensitive Fluoroimmunoassay. J Agric Food Chem. 2022 Apr 06; 70(13):4102-4111.
Chen ZJ, Zhang YF, Chen JL, Lin ZS, Wu MF, Shen YD, Luo L, Wang H, Wen XW, Hammock B, Lei HT, Xu ZL. PMID: 35333506; PMCID: PMC9484545.
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PubMed Mentions:
3 Fields:
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sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2120691119.
Bergmann CB, McReynolds CB, Wan D, Singh N, Goetzman H, Caldwell CC, Supp DM, Hammock BD. PMID: 35312372; PMCID: PMC9060469.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint. Inflammopharmacology. 2022 Jun; 30(3):981-990.
Abdalla HB, Napimoga MH, Teixeira JM, Trindade-da-Silva CA, Pieroni VL, Dos Santos Araújo FSM, Hammock BD, Clemente-Napimoga JT. PMID: 35303234; PMCID: PMC9578439.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury. J Adv Res. 2023 01; 43:163-174.
Leuillier M, Duflot T, Ménoret S, Messaoudi H, Djerada Z, Groussard D, Denis RGP, Chevalier L, Karoui A, Panthu B, Thiébaut PA, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Féliu C, Peyret H, Nicol L, Henry JP, Renet S, Mulder P, Wan D, Tesson L, Heslan JM, Duché A, Jacques S, Ziegler F, Brunel V, Rautureau GJP, Monteil C, do Rego JL, do Rego JC, Afonso C, Hammock B, Madec AM, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. PMID: 36585106; PMCID: PMC9811321.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022 03 24; 65(6):4909-4925.
Codony S, Pont C, Griñán-Ferré C, Di Pede-Mattatelli A, Calvó-Tusell C, Feixas F, Osuna S, Jarné-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Pérez B, Bartra C, Sanfeliu C, Juárez-Jiménez J, Morisseau C, Hammock BD, Pallàs M, Vázquez S, Muñoz-Torrero D. PMID: 35271276; PMCID: PMC8958510.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain. Arthritis Rheumatol. 2022 04; 74(4):623-633.
Gowler PRW, Turnbull J, Shahtaheri M, Gohir S, Kelly T, McReynolds C, Yang J, Jha RR, Fernandes GS, Zhang W, Doherty M, Walsh DA, Hammock BD, Valdes AM, Barrett DA, Chapman V. PMID: 34672113; PMCID: PMC8957539.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
Sun CP, Zhou JJ, Yu ZL, Huo XK, Zhang J, Morisseau C, Hammock BD, Ma XC. PMID: 35217618; PMCID: PMC8892522.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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A competitive immunoassay for detecting triazophos based on fluorescent catalytic hairpin self-assembly. Mikrochim Acta. 2022 02 21; 189(3):114.
Wang Y, Abd El-Aty AM, Chen G, Jia H, Cui X, Xu L, Cao Z, She Y, Jin F, Zhang Y, Hacimuftuoglu A, Lamu S, Wang J, Zheng L, Jin M, Hammock BD. PMID: 35190860; PMCID: PMC10111248.
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PubMed Mentions:
4 Fields:
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Development of a Rapid Gold Nanoparticle Immunochromatographic Strip Based on the Nanobody for Detecting 2,4-DichloRophenoxyacetic Acid. Biosensors (Basel). 2022 Jan 30; 12(2).
Zhou H, He C, Li Z, Huo J, Xue Y, Xu X, Qi M, Chen L, Hammock BD, Zhang J. PMID: 35200344; PMCID: PMC8869386.
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PubMed Mentions:
4 Fields:
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A Polydopamine-Coated Gold Nanoparticles Quenching Quantum Dots-Based Dual-Readout Lateral Flow Immunoassay for Sensitive Detection of Carbendazim in Agriproducts. Biosensors (Basel). 2022 Jan 29; 12(2).
Mao X, Wang Y, Jiang L, Zhang H, Zhao Y, Liu P, Liu J, Hammock BD, Zhang C. PMID: 35200343; PMCID: PMC8869244.
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PubMed Mentions:
1 Fields:
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Nanobodies for Accurate Recognition of Iso-tenuazonic Acid and Development of Sensitive Immunoassay for Contaminant Detection in Foods. Food Control. 2022 Jun; 136.
Wang F, Yang YY, Wan DB, Li JD, Liang YF, Li ZF, Shen YD, Xu ZL, Yang JY, Wang H, Gettemans J, Hammock BD, Sun YM. PMID: 35989708; PMCID: PMC9390337.
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PubMed Mentions:
1
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Sex-Specific Differences in Resolution of Airway Inflammation in Fat-1 Transgenic Mice Following Repetitive Agricultural Dust Exposure. Front Pharmacol. 2021; 12:785193.
Ulu A, Velazquez JV, Burr A, Sveiven SN, Yang J, Bravo C, Hammock BD, Nordgren TM. PMID: 35095496; PMCID: PMC8793679.
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PubMed Mentions:
2
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Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysis. Mycotoxin Res. 2022 Feb; 38(1):51-60.
Pang Q, Chen Y, Mukhtar H, Xiong J, Wang X, Xu T, Hammock BD, Wang J. PMID: 35023020; PMCID: PMC8754551.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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"Ready-to-use" immunosensor for the detection of small molecules with fast readout. Biosens Bioelectron. 2022 Apr 01; 201:113968.
Ding Y, Cui P, Chen H, Li J, Huang L, González-Sapienza G, Hammock BD, Wang M, Hua X. PMID: 35007993; PMCID: PMC8863114.
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PubMed Mentions:
3 Fields:
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A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry. Molecules. 2022 Jan 03; 27(1).
Wan D, Morisseau C, Hammock BD, Yang J. PMID: 35011515; PMCID: PMC8747065.
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PubMed Mentions: Fields:
Translation:
Humans
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COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl 4 -Induced Liver Fibrosis and Portal Hypertension. Front Med (Lausanne). 2021; 8:761517.
Zhao Z, Zhang C, Lin J, Zheng L, Li H, Qi X, Huo H, Lou X, Hammock BD, Hwang SH, Bao Y, Luo M. PMID: 35004731; PMCID: PMC8734593.
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PubMed Mentions:
4
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Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. Front Pharmacol. 2021; 12:778470.
Wagner KM, Yang J, Morisseau C, Hammock BD. PMID: 34975481; PMCID: PMC8719166.
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PubMed Mentions:
1
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2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity. Pharmaceuticals (Basel). 2021 Dec 17; 14(12).
Martín-López J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vázquez S. PMID: 34959721; PMCID: PMC8703317.
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PubMed Mentions:
2
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Author Correction: Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2021 Dec 14; 11(1):24259.
Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 34907191; PMCID: PMC8671385.
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PubMed Mentions: Fields:
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Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity. Front Pharmacol. 2021; 12:744776.
Jankiewicz WK, Barnett SD, Stavniichuk A, Hwang SH, Hammock BD, Belayet JB, Khan AH, Imig JD. PMID: 34955823; PMCID: PMC8695932.
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PubMed Mentions:
3
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New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. Chem Res Toxicol. 2021 12 20; 34(12):2579-2591.
Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD. PMID: 34817988; PMCID: PMC8853703.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Soluble epoxide hydrolase inhibitor can protect the femoral head against tobacco smoke exposure-induced osteonecrosis in spontaneously hypertensive rats. Toxicology. 2022 01 15; 465:153045.
Xu J, Qiu X, Yu G, Ly M, Yang J, Silva RM, Zhang X, Yu M, Wang Y, Hammock B, Pinkerton KE, Zhao D. PMID: 34801612; PMCID: PMC9484547.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021 12 01; 51:116507.
Wilt S, Kodani S, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 34794001; PMCID: PMC8900675.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Eicosanoid regulation of debris-stimulated metastasis. Proc Natl Acad Sci U S A. 2021 10 12; 118(41).
Deng J, Yang H, Haak VM, Yang J, Kipper FC, Barksdale C, Hwang SH, Gartung A, Bielenberg DR, Subbian S, Ho KK, Ye X, Fan D, Sun Y, Hammock BD, Panigrahy D. PMID: 34607951; PMCID: PMC8521662.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for sensitive detection of 1-naphthol for the exposure assessment of pesticide carbaryl. J Hazard Mater. 2022 02 15; 424(Pt C):127411.
Chen ZJ, Wu HL, Shen YD, Wang H, Zhang YF, Hammock B, Li ZF, Luo L, Lei HT, Xu ZL. PMID: 34629198; PMCID: PMC8877597.
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PubMed Mentions:
3 Fields:
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Smartphone-Based Dual-Channel Immunochromatographic Test Strip with Polymer Quantum Dot Labels for Simultaneous Detection of Cypermethrin and 3-Phenoxybenzoic Acid. Anal Chem. 2021 10 12; 93(40):13658-13666.
Zhao Y, Ruan X, Song Y, Smith JN, Vasylieva N, Hammock BD, Lin Y, Du D. PMID: 34591463; PMCID: PMC8655817.
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PubMed Mentions:
7 Fields:
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Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain. Acta Pharm Sin B. 2022 Mar; 12(3):1377-1389.
Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G. PMID: 35530144; PMCID: PMC9072249.
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PubMed Mentions:
3
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Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction. Cardiovasc Drugs Ther. 2023 02; 37(1):25-37.
Thai PN, Ren L, Xu W, Overton J, Timofeyev V, Nader CE, Haddad M, Yang J, Gomes AV, Hammock BD, Chiamvimonvat N, Sirish P. PMID: 34499283; PMCID: PMC8904649.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Enhanced Bio-Barcode Immunoassay Using Droplet Digital PCR for Multiplex Detection of Organophosphate Pesticides. J Agric Food Chem. 2021 Sep 22; 69(37):11131-11141.
Cui X, Abd El-Aty AM, Zhang C, Xu L, Liu H, Jia H, Wang Y, Cao Z, Salvador JP, She Y, Jin F, Wang J, Jin M, Hammock BD. PMID: 34494438.
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PubMed Mentions:
1 Fields:
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Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure. Clin Psychopharmacol Neurosci. 2021 Aug 31; 19(3):554-558.
Pu Y, Ma L, Shan J, Wan X, Hammock BD, Hashimoto K. PMID: 34294625; PMCID: PMC8316667.
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PubMed Mentions:
4
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Pharmacokinetics, Metabolite Measurement, and Biomarker Identification of Dermal Exposure to Permethrin Using Accelerator Mass Spectrometry. Toxicol Sci. 2021 08 30; 183(1):49-59.
Buchholz BA, Ahn KC, Huang H, Gee SJ, Stewart BJ, Ognibene TJ, Hammock BD. PMID: 34460930; PMCID: PMC8404990.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Sortase-Mediated Phage Decoration for Analytical Applications. Anal Chem. 2021 08 31; 93(34):11800-11808.
Ding Y, Chen H, Li J, Huang L, Song G, Li Z, Hua X, Gonzalez-Sapienza G, Hammock BD, Wang M. PMID: 34415158; PMCID: PMC8853704.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development. Molecules. 2021 Aug 19; 26(16).
McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. PMID: 34443621; PMCID: PMC8399023.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway. Food Chem Toxicol. 2021 Oct; 156:112516.
Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC. PMID: 34411643; PMCID: PMC8889936.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function. Sci Rep. 2021 08 16; 11(1):16555.
Bergmann CB, Hammock BD, Wan D, Gogolla F, Goetzman H, Caldwell CC, Supp DM. PMID: 34400718; PMCID: PMC8368302.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. Br J Pharmacol. 2021 11; 178(22):4468-4484.
Khan MAH, Hwang SH, Barnett SD, Stavniichuk A, Jankiewicz WK, Hammock BD, Imig JD. PMID: 34255857; PMCID: PMC8863090.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detection of ochratoxin A. J Hazard Mater. 2022 01 15; 422:126838.
Su B, Zhang Z, Sun Z, Tang Z, Xie X, Chen Q, Cao H, Yu X, Xu Y, Liu X, Hammock BD. PMID: 34411960; PMCID: PMC8889937.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCellsPHPublic Health
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EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. Elife. 2021 08 03; 10.
Gautheron J, Morisseau C, Chung WK, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Fève B, Vigouroux C, Andreelli F, Jeru I. PMID: 34342583; PMCID: PMC8331186.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice. Int J Mol Sci. 2021 Jul 31; 22(15).
Yang Y, Xu X, Wu H, Yang J, Chen J, Morisseau C, Hammock BD, Bettaieb A, Zhao L. PMID: 34361032; PMCID: PMC8347952.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Development of a direct competitive enzyme-linked immunosorbent assay for quantitation of sodium saccharin residue in food. J Food Sci. 2021 Aug; 86(8):3720-3729.
Zhao Y, Wang M, Zhang M, Yang X, Li Z, Vasylieva N, Tan G, Wang B, Hammock BD. PMID: 34309034; PMCID: PMC9514150.
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PubMed Mentions: Fields:
Translation:
PHPublic Health
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Immune response dynamics in COVID-19 patients to SARS-CoV-2 and other human coronaviruses. PLoS One. 2021; 16(7):e0254367.
Ravindran R, McReynolds C, Yang J, Hammock BD, Ikram A, Ali A, Bashir A, Zohra T, Chang WLW, Hartigan-O'Connor DJ, Rashidi HH, Khan IH. PMID: 34242356; PMCID: PMC8270414.
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Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome. Drug Metab Dispos. 2021 09; 49(9):810-821.
Fang Y, Johnson H, Anderl JL, Muchamuel T, McMinn D, Morisseau C, Hammock BD, Kirk C, Wang J. PMID: 34234005.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis. Eur J Med Chem. 2021 Nov 05; 223:113678.
Du F, Sun W, Morisseau C, Hammock BD, Bao X, Liu Q, Wang C, Zhang T, Yang H, Zhou J, Xiao W, Liu Z, Chen G. PMID: 34218083; PMCID: PMC8877601.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve. J Affect Disord. 2021 09 01; 292:565-573.
Wang S, Ishima T, Qu Y, Shan J, Chang L, Wei Y, Zhang J, Pu Y, Fujita Y, Tan Y, Wang X, Ma L, Wan X, Hammock BD, Hashimoto K. PMID: 34147969; PMCID: PMC8282729.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop. Nutrients. 2021 May 31; 13(6).
Baek SJ, Hammock BD, Hwang IK, Li Q, Moustaid-Moussa N, Park Y, Safe S, Suh N, Yi SS, Zeldin DC, Zhong Q, Bradbury JA, Edin ML, Graves JP, Jung HY, Jung YH, Kim MB, Kim W, Lee J, Li H, Moon JS, Yoo ID, Yue Y, Lee JY, Han HJ. PMID: 34072678; PMCID: PMC8227583.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss. Free Radic Biol Med. 2021 08 20; 172:48-57.
Koike S, Hsu MF, Bettaieb A, Chu B, Matsumoto N, Morisseau C, Havel PJ, Huising MO, Hammock BD, Haj FG. PMID: 34038767; PMCID: PMC9901526.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. Antioxidants (Basel). 2021 May 20; 10(5).
Mavangira V, Kuhn MJ, Abuelo A, Morisseau C, Hammock BD, Sordillo LM. PMID: 34065244; PMCID: PMC8161397.
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PubMed Mentions:
3
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A sensitive bio-barcode immunoassay based on bimetallic Au@Pt nanozyme for detection of organophosphate pesticides in various agro-products. Food Chem. 2021 Nov 15; 362:130118.
Chen G, Liu G, Jia H, Cui X, Wang Y, Li D, Zheng W, She Y, Xu D, Huang X, Abd El-Aty AM, Sun J, Liu H, Zou Y, Wang J, Jin M, Hammock BD. PMID: 34082296; PMCID: PMC9648569.
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PubMed Mentions:
6 Fields:
Translation:
CellsPHPublic Health
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Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. Int J Mol Sci. 2021 May 08; 22(9).
Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD. PMID: 34066758; PMCID: PMC8125816.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. J Med Chem. 2021 05 13; 64(9):5429-5446.
Codony S, Calvó-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Pérez C, Rodríguez-Franco MI, Pizarro-Delgado J, Corpas R, Griñán-Ferré C, Pallàs M, Sanfeliu C, Vázquez-Carrera M, Hammock BD, Feixas F, Vázquez S. PMID: 33945278; PMCID: PMC8634379.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis. Int J Mol Sci. 2021 Apr 28; 22(9).
Jonnalagadda D, Wan D, Chun J, Hammock BD, Kihara Y. PMID: 33925035; PMCID: PMC8125305.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit juices with a specific camel polyclonal antibody. Anal Methods. 2021 04 22; 13(15):1795-1802.
Wang F, Wan DB, Shen YD, Tian YX, Xiao ZL, Xu ZL, Yang JY, Sun YM, Hammock BD, Wang H. PMID: 33885655.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Enhanced Non-Toxic Immunodetection of Alternaria Mycotoxin Tenuazonic Acid Based on Ferritin-Displayed Anti-Idiotypic Nanobody-Nanoluciferase Multimers. J Agric Food Chem. 2021 Apr 28; 69(16):4911-4917.
Wang F, Li ZF, Wan DB, Vasylieva N, Shen YD, Xu ZL, Yang JY, Gettemans J, Wang H, Hammock BD, Sun YM. PMID: 33870684.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections. Front Physiol. 2021; 12:663869.
McReynolds CB, Cortes-Puch I, Ravindran R, Khan IH, Hammock BG, Shih PB, Hammock BD, Yang J. PMID: 33868029; PMCID: PMC8047414.
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PubMed Mentions:
26
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Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. Sci Rep. 2021 03 29; 11(1):7042.
Tiwari S, Yang J, Morisseau C, Durbin-Johnson B, Hammock BD, Gomes AV. PMID: 33782432; PMCID: PMC8007717.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Development of nanobody-based flow-through dot ELISA and lateral-flow immunoassay for rapid detection of 3-phenoxybenzoic acid. Anal Methods. 2021 04 14; 13(14):1757-1765.
Zhang C, Wu X, Li D, Hu J, Wan D, Zhang Z, Hammock BD. PMID: 33861243; PMCID: PMC8442667.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain. ACS Omega. 2021 Mar 16; 6(10):7165-7174.
Singh N, Barnych B, Wagner KM, Wan D, Morisseau C, Hammock BD. PMID: 33748630; PMCID: PMC7970556.
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PubMed Mentions:
10
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Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence Enzyme Immunoassay for trace Glypican-3 in Serum. Sens Actuators B Chem. 2021 Jun 01; 336.
Yu S, Li Z, Li J, Zhao S, Wu S, Liu H, Bi X, Li D, Dong J, Duan S, Hammock BD. PMID: 35250176; PMCID: PMC8896807.
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PubMed Mentions:
4
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Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor immunotherapy. Signal Transduct Target Ther. 2021 02 25; 6(1):80.
Mo F, Duan S, Jiang X, Yang X, Hou X, Shi W, Carlos CJJ, Liu A, Yin S, Wang W, Yao H, Yu Z, Tang Z, Xie S, Ding Z, Zhao X, Hammock BD, Lu X. PMID: 33627635; PMCID: PMC7904846.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chlorantraniliprole in soil and the vegetable bok choy. Anal Bioanal Chem. 2021 Apr; 413(9):2503-2511.
Xu B, Wang K, Vasylieva N, Zhou H, Xue X, Wang B, Li QX, Hammock BD, Xu T. PMID: 33580830; PMCID: PMC8422987.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. Int J Mol Sci. 2021 Feb 08; 22(4).
Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM. PMID: 33567578; PMCID: PMC7915306.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative. J Med Chem. 2021 02 25; 64(4):1856-1872.
Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. PMID: 33550801; PMCID: PMC7917437.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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HIV-related Neuropathy: Pathophysiology, Treatment and Challenges. J Neurol Exp Neurosci. 2021; 7(1):15-24.
Jazebi N, Evans C, Kadaru HS, Kompella D, Raji M, Fang F, Pappolla M, Tang SJ, Chung JM, Hammock B, Fang X. PMID: 35252633; PMCID: PMC8896895.
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PubMed Mentions:
4
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Fusion expression of nanobodies specific for the insecticide fipronil on magnetosomes in Magnetospirillum gryphiswaldense MSR-1. J Nanobiotechnology. 2021 Jan 19; 19(1):27.
Wu S, Ma F, He J, Li QX, Hammock BD, Tian J, Xu T. PMID: 33468141; PMCID: PMC7816308.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence. J Pain Res. 2021; 14:61-72.
Wang Y, Wagner KM, Morisseau C, Hammock BD. PMID: 33488116; PMCID: PMC7814236.
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PubMed Mentions:
15
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Reply to Reeves and Dunn: Risk for autism in offspring after maternal glyphosate exposure. Proc Natl Acad Sci U S A. 2021 01 12; 118(2).
Hashimoto K, Hammock BD. PMID: 33443192; PMCID: PMC7812790.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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A visual bio-barcode immunoassay for sensitive detection of triazophos based on biochip silver staining signal amplification. Food Chem. 2021 Jun 15; 347:129024.
Wang Y, Du P, Abd El-Aty AM, Chen G, Jia H, Cui X, Oz E, Zhang Y, Zhang X, Qin G, Yan F, Wang J, Jin M, Hammock BD. PMID: 33461115; PMCID: PMC9648568.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. J Med Chem. 2021 01 14; 64(1):184-215.
Sun CP, Zhang XY, Morisseau C, Hwang SH, Zhang ZJ, Hammock BD, Ma XC. PMID: 33369424; PMCID: PMC7942193.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy. J Mol Cell Cardiol. 2021 05; 154:80-91.
Wang L, Zhao D, Tang L, Li H, Liu Z, Gao J, Edin ML, Zhang H, Zhang K, Chen J, Zhu X, Wang D, Zeldin DC, Hammock BD, Wang J, Huang H. PMID: 33378686; PMCID: PMC8068623.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain. J Nat Prod. 2020 12 24; 83(12):3689-3697.
Singh N, Barnych B, Morisseau C, Wagner KM, Wan D, Takeshita A, Pham H, Xu T, Dandekar A, Liu JY, Hammock BD. PMID: 33320645; PMCID: PMC7888481.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
-
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. Sci Transl Med. 2020 12 09; 12(573).
Ghosh A, Comerota MM, Wan D, Chen F, Propson NE, Hwang SH, Hammock BD, Zheng H. PMID: 33298560; PMCID: PMC7784555.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimals
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EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua. Sci Rep. 2020 11 19; 10(1):20183.
Vatanparast M, Ahmed S, Lee DH, Hwang SH, Hammock B, Kim Y. PMID: 33214688; PMCID: PMC7677322.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizing Enzymes Involved. Nutrients. 2020 Oct 28; 12(11).
Tu M, Wang W, Zhang G, Hammock BD. PMID: 33126566; PMCID: PMC7693568.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABAA Receptor. Mol Pharmacol. 2021 01; 99(1):78-91.
Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. PMID: 33109687; PMCID: PMC7746976.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors. J Clin Pharmacol. 2021 04; 61(4):531-537.
An G, Lee KSS, Yang J, Hammock BD. PMID: 33078430; PMCID: PMC7969377.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 2021; 11(3):815-830.
Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG. PMID: 33068774; PMCID: PMC7851189.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Development of a sensitive non-competitive immunoassay via immunocomplex binding peptide for the determination of ethyl carbamate in wine samples. J Hazard Mater. 2021 03 15; 406:124288.
Fu HJ, Chen ZJ, Wang H, Luo L, Wang Y, Huang RM, Xu ZL, Hammock B. PMID: 33525128; PMCID: PMC8893042.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease. Neurotherapeutics. 2020 10; 17(4):1825-1835.
Griñán-Ferré C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R, Sanfeliu C, Pérez B, Loza MI, Brea J, Morisseau C, Hammock BD, Vázquez S, Pallàs M, Galdeano C. PMID: 32488482; PMCID: PMC7851240.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. Sci Rep. 2020 09 29; 10(1):16032.
Knuth MM, Mahapatra D, Jima D, Wan D, Hammock BD, Law M, Kullman SW. PMID: 32994480; PMCID: PMC7524799.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity. Int J Mol Sci. 2020 Sep 24; 21(19).
Overby H, Yang Y, Xu X, Graham K, Hildreth K, Choi S, Wan D, Morisseau C, Zeldin DC, Hammock BD, Wang S, Bettaieb A, Zhao L. PMID: 32987880; PMCID: PMC7582898.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine. Neuropsychopharmacol Rep. 2020 12; 40(4):412-416.
Wan X, Fujita Y, Chang L, Wei Y, Ma L, Wuyun G, Pu Y, Hammock BD, Hashimoto K. PMID: 32896112; PMCID: PMC7722641.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in a hypertensive model of chronic cerebral hypoperfusion. Microcirculation. 2021 01; 28(1):e12653.
Matin N, Fisher C, Lansdell TA, Hammock BD, Yang J, Jackson WF, Dorrance AM. PMID: 32767848; PMCID: PMC7990111.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Carcinogenesis: Failure of resolution of inflammation? Pharmacol Ther. 2021 02; 218:107670.
Fishbein A, Hammock BD, Serhan CN, Panigrahy D. PMID: 32891711; PMCID: PMC7470770.
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PubMed Mentions:
59 Fields:
Translation:
Humans
-
Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 11 15; 28(22):115735.
Lee KSS, Ng JC, Yang J, Hwang SH, Morisseau C, Wagner K, Hammock BD. PMID: 33007552; PMCID: PMC7914304.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery. Nat Chem. 2020 10; 12(10):906-913.
Brighty GJ, Botham RC, Li S, Nelson L, Mortenson DE, Li G, Morisseau C, Wang H, Hammock BD, Sharpless KB, Kelly JW. PMID: 32868886; PMCID: PMC7541551.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies. Bioorg Chem. 2020 10; 103:104165.
Wilt S, Kodani S, Le TNH, Nguyen L, Vo N, Ly T, Rodriguez M, Hudson PK, Morisseau C, Hammock BD, Pecic S. PMID: 32891856; PMCID: PMC7723751.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci. 2020; 7:580.
Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. PMID: 33005645; PMCID: PMC7479175.
View in:
PubMed Mentions:
2
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2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis. J Med Chem. 2020 09 10; 63(17):9237-9257.
Codony S, Pujol E, Pizarro J, Feixas F, Valverde E, Loza MI, Brea JM, Saez E, Oyarzabal J, Pineda-Lucena A, Pérez B, Pérez C, Rodríguez-Franco MI, Leiva R, Osuna S, Morisseau C, Hammock BD, Vázquez-Carrera M, Vázquez S. PMID: 32787085; PMCID: PMC7755424.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its contamination in environmental water. Sci Total Environ. 2021 Jan 20; 753:141950.
Li ZF, Dong JX, Vasylieva N, Cui YL, Wan DB, Hua XD, Huo JQ, Yang DC, Gee SJ, Hammock BD. PMID: 32906044; PMCID: PMC7674261.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. J Nutr Biochem. 2020 12; 86:108484.
Hildreth K, Kodani SD, Hammock BD, Zhao L. PMID: 32827665; PMCID: PMC7606796.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer. Anal Chem. 2020 09 01; 92(17):11654-11663.
Li D, Cui Y, Morisseau C, Wagner KM, Cho YS, Hammock BD. PMID: 32786492; PMCID: PMC7745732.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Early antihypertensive treatment and ischemia-induced acute kidney injury. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F563-F570.
Greite R, Derlin K, Hensen B, Thorenz A, Rong S, Chen R, Hellms S, Jang MS, Bräsen JH, Meier M, Willenberg I, Immenschuh S, Haller H, Luft FC, Panigrahy D, Hwang SH, Hammock BD, Schebb NH, Gueler F. PMID: 32799675; PMCID: PMC7642887.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21576-21587.
Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D. PMID: 32801214; PMCID: PMC7474612.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy. Stem Cells Transl Med. 2020 12; 9(12):1570-1584.
Sirish P, Thai PN, Lee JH, Yang J, Zhang XD, Ren L, Li N, Timofeyev V, Lee KSS, Nader CE, Rowland DJ, Yechikov S, Ganaga S, Young N, Lieu DK, Yamoah EN, Hammock BD, Chiamvimonvat N. PMID: 32790136; PMCID: PMC7695637.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycotoxin by Exploitation of Nanobody and Nanobody-Nanoluciferase Fusion. Anal Chem. 2020 09 01; 92(17):11935-11942.
Wang F, Li ZF, Yang YY, Wan DB, Vasylieva N, Zhang YQ, Cai J, Wang H, Shen YD, Xu ZL, Hammock BD. PMID: 32702970; PMCID: PMC7743996.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Generation of functional single-chain fragment variable from hybridoma and development of chemiluminescence enzyme immunoassay for determination of total malachite green in tilapia fish. Food Chem. 2021 Feb 01; 337:127780.
Dong J, Li Z, Wang Y, Jin M, Shen Y, Xu Z, Abd El-Aty AM, Gee SJ, Hammock BD, Sun Y, Wang H. PMID: 32799164; PMCID: PMC7541715.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCellsPHPublic Health
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1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats. Eur Rev Med Pharmacol Sci. 2020 08; 24(15):8143-8150.
Bukhari IA, Alorainey BI, Al-Motrefi AA, Mahmoud A, Campbell WB, Hammock BD. PMID: 32767352; PMCID: PMC7990106.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
On-spot quantitative analysis of dicamba in field waters using a lateral flow immunochromatographic strip with smartphone imaging. Anal Bioanal Chem. 2020 Oct; 412(25):6995-7006.
Qi M, Huo J, Li Z, He C, Li D, Wang Y, Vasylieva N, Zhang J, Hammock BD. PMID: 32737550; PMCID: PMC7771584.
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PubMed Mentions:
2 Fields:
-
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats. Int Immunopharmacol. 2020 Oct; 87:106841.
Teixeira JM, Abdalla HB, Basting RT, Hammock BD, Napimoga MH, Clemente-Napimoga JT. PMID: 32736189; PMCID: PMC8015648.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2020 09 15; 30(18):127430.
Burmistrov V, Morisseau C, Karlov D, Pitushkin D, Vernigora A, Rasskazova E, Butov GM, Hammock BD. PMID: 32736212; PMCID: PMC7494652.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for the Detection of Cyproheptadine Hydrochloride in Animal-Derived Food. Front Chem. 2020; 8:575.
Li P, Yang C, Liu B, Wu Q, Wang Y, Dong S, Zhang H, Vasylieva N, Hammock BD, Zhang C. PMID: 32760698; PMCID: PMC7372008.
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PubMed Mentions:
1
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Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)? Am J Pathol. 2020 09; 190(9):1782-1788.
Hammock BD, Wang W, Gilligan MM, Panigrahy D. PMID: 32650004; PMCID: PMC7340586.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion for the Detection of Tetrabromobisphenol A in Sediment. Anal Chem. 2020 07 21; 92(14):10083-10090.
Li Z, Wang Y, Vasylieva N, Wan D, Yin Z, Dong J, Hammock BD. PMID: 32559059; PMCID: PMC7780847.
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PubMed Mentions:
7 Fields:
Translation:
PHPublic Health
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Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice. J Agric Food Chem. 2020 Jul 22; 68(29):7641-7647.
Xie M, Yang J, Zhang J, Sherman HL, Zhang Z, Minter LM, Hammock BD, Park Y, Zhang G. PMID: 32594738; PMCID: PMC7901524.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain. Neurotherapeutics. 2020 07; 17(3):900-916.
Wagner KM, Gomes A, McReynolds CB, Hammock BD. PMID: 32875445; PMCID: PMC7609775.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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Monitoring of the Organophosphate Pesticide Chlorpyrifos in Vegetable Samples from Local Markets in Northern Thailand by Developed Immunoassay. Int J Environ Res Public Health. 2020 06 30; 17(13).
Hongsibsong S, Prapamontol T, Xu T, Hammock BD, Wang H, Chen ZJ, Xu ZL. PMID: 32630084; PMCID: PMC7369984.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsPHPublic Health
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Development of a nanobody tagged with streptavidin-binding peptide and its application in a Luminex fluoroimmunoassay for alpha fetal protein in serum. RSC Adv. 2020 Jun 19; 10(40):23767-23774.
Chen Q, Sun D, Pei H, Su B, Bao K, Cao H, Zhang C, Hammock BD, Liu X. PMID: 35517360; PMCID: PMC9054930.
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PubMed Mentions:
2
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A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environmental toxin. Electroanalysis. 2020 Sep; 32(9):2056-2064.
Kumar S, Vasylieva N, Singh V, Hammock B, Singh SG. PMID: 33456276; PMCID: PMC7806194.
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PubMed Mentions:
1
-
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? Cancer Metastasis Rev. 2020 06; 39(2):337-340.
Panigrahy D, Gilligan MM, Huang S, Gartung A, Cortés-Puch I, Sime PJ, Phipps RP, Serhan CN, Hammock BD. PMID: 32385712; PMCID: PMC7207990.
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PubMed Mentions:
123 Fields:
Translation:
HumansCellsPHPublic Health
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Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model. FASEB J. 2020 07; 34(7):9074-9086.
Trindade-da-Silva CA, Clemente-Napimoga JT, Abdalla HB, Rosa SM, Ueira-Vieira C, Morisseau C, Verri WA, Montalli VAM, Hammock BD, Napimoga MH. PMID: 32400048; PMCID: PMC7383812.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11753-11759.
Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. PMID: 32398374; PMCID: PMC7260984.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsPHPublic Health
-
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression. Sci Rep. 2020 05 12; 10(1):7843.
Huerta-Yepez S, Tirado-Rodriguez A, Montecillo-Aguado MR, Yang J, Hammock BD, Hankinson O. PMID: 32398692; PMCID: PMC7217871.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids. Cells. 2020 04 29; 9(5).
Edin ML, Lih FB, Hammock BD, Thomson S, Zeldin DC, Bishop-Bailey D. PMID: 32365470; PMCID: PMC7290345.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients. Anal Chem. 2020 05 19; 92(10):7334-7342.
Li D, Morisseau C, McReynolds CB, Duflot T, Bellien J, Nagra RM, Taha AY, Hammock BD. PMID: 32253910; PMCID: PMC7744119.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis. J Affect Disord. 2020 06 01; 270:131-134.
Zhang J, Tan Y, Chang L, Hammock BD, Hashimoto K. PMID: 32339103; PMCID: PMC7243919.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide Hydrolase. J Pharmacol Exp Ther. 2020 07; 374(1):223-232.
Wu N, Hammock BD, Lee KSS, An G. PMID: 32238455; PMCID: PMC7318792.
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PubMed Mentions:
5 Fields:
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Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice. Arch Toxicol. 2020 06; 94(6):1995-2007.
Pressly B, Vasylieva N, Barnych B, Singh V, Singh L, Bruun DA, Hwang SH, Chen YJ, Fettinger JC, Johnnides S, Lein PJ, Yang J, Hammock BD, Wulff H. PMID: 32239239; PMCID: PMC7303059.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and development of an easy-to-use ELISA in urine samples. Ecotoxicol Environ Saf. 2020 Jun 15; 196:110533.
Chen ZJ, Liu XX, Xiao ZL, Fu HJ, Huang YP, Huang SY, Shen YD, He F, Yang XX, Hammock B, Xu ZL. PMID: 32247241; PMCID: PMC7200204.
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PubMed Mentions:
10 Fields:
Translation:
PHPublic Health
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Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation. Proc Natl Acad Sci U S A. 2020 04 14; 117(15):8431-8436.
Wang Y, Yang J, Wang W, Sanidad KZ, Cinelli MA, Wan D, Hwang SH, Kim D, Lee KSS, Xiao H, Hammock BD, Zhang G. PMID: 32220957; PMCID: PMC7165420.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation. Theranostics. 2020; 10(11):4749-4761.
Yang HH, Duan JX, Liu SK, Xiong JB, Guan XX, Zhong WJ, Sun CC, Zhang CY, Luo XQ, Zhang YF, Chen P, Hammock BD, Hwang SH, Jiang JX, Zhou Y, Guan CX. PMID: 32308747; PMCID: PMC7163435.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 01; 193:112206.
Barnych B, Singh N, Negrel S, Zhang Y, Magis D, Roux C, Hua X, Ding Z, Morisseau C, Tantillo DJ, Siegel JB, Hammock BD. PMID: 32203787; PMCID: PMC7366823.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Single-chain variable fragment antibody-based immunochromatographic strip for rapid detection of fumonisin B1 in maize samples. Food Chem. 2020 Jul 30; 319:126546.
Ren W, Xu Y, Huang Z, Li Y, Tu Z, Zou L, He Q, Fu J, Liu S, Hammock BD. PMID: 32179370.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress. Biomed Pharmacother. 2020 Jun; 126:109907.
Zhang YF, Sun CC, Duan JX, Yang HH, Zhang CY, Xiong JB, Zhong WJ, Zu C, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX. PMID: 32114358; PMCID: PMC8868492.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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A sensitive fluorometric bio-barcodes immunoassay for detection of triazophos residue in agricultural products and water samples by iterative cycles of DNA-RNA hybridization and dissociation of fluorophores by Ribonuclease H. Sci Total Environ. 2020 May 15; 717:137268.
Zhang X, Du P, Cui X, Chen G, Wang Y, Zhang Y, Abd El-Aty AM, Hacimüftüoglu A, Wang J, He H, Jin M, Hammock B. PMID: 32084695; PMCID: PMC7938870.
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PubMed Mentions:
4 Fields:
-
Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase. Br J Pharmacol. 2020 04; 177(8):1793-1805.
Liu G, Wu F, Jiang X, Que Y, Qin Z, Hu P, Lee KSS, Yang J, Zeng C, Hammock BD, Tong X. PMID: 31758704; PMCID: PMC7070168.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials and molecular dynamics. Bioorg Chem. 2020 03; 96:103637.
Sun CP, Zhang J, Zhao WY, Yi J, Yan JK, Wang YL, Morisseau C, Liu ZB, Hammock BD, Ma XC. PMID: 32032849; PMCID: PMC7233170.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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An Innovative Nanobody-Based Electrochemical Immunosensor Using Decorated Nylon Nanofibers for Point-of-Care Monitoring of Human Exposure to Pyrethroid Insecticides. ACS Appl Mater Interfaces. 2020 Feb 05; 12(5):6159-6168.
El-Moghazy AY, Huo J, Amaly N, Vasylieva N, Hammock BD, Sun G. PMID: 31927905; PMCID: PMC7799635.
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PubMed Mentions:
10 Fields:
Translation:
HumansPHPublic Health
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PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice. Biochem Biophys Res Commun. 2020 03 19; 523(4):1020-1026.
Sun CC, Zhang CY, Duan JX, Guan XX, Yang HH, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX, Liu SK, Zhang J. PMID: 31973813; PMCID: PMC7990110.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Assessment of soluble epoxide hydrolase activity in vivo: A metabolomic approach. Prostaglandins Other Lipid Mediat. 2020 06; 148:106410.
Stefanovski D, Shih PB, Hammock BD, Watanabe RM, Youn JH. PMID: 31931080; PMCID: PMC7237305.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatment techniques. Environ Chem. 2020; 17(1):1-5.
Späth J, Nording M, Lindberg R, Brodin T, Jansson S, Yang J, Wan D, Hammock B, Fick J. PMID: 33692653; PMCID: PMC7943040.
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PubMed Mentions:
1
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Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation. Adv Exp Med Biol. 2020; 1274:71-99.
McReynolds C, Morisseau C, Wagner K, Hammock B. PMID: 32894508; PMCID: PMC7737916.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility. Bioorg Med Chem Lett. 2020 02 01; 30(3):126908.
Burmistrov V, Morisseau C, D'yachenko V, Karlov D, Butov GM, Hammock BD. PMID: 31870649; PMCID: PMC6957307.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Construction of Immunomagnetic Particles with High Stability in Stringent Conditions by Site-Directed Immobilization of Multivalent Nanobodies onto Bacterial Magnetic Particles for the Environmental Detection of Tetrabromobisphenol-A. Anal Chem. 2020 01 07; 92(1):1114-1121.
He J, Ma S, Wu S, Xu J, Tian J, Li J, Gee SJ, Hammock BD, Li QX, Xu T. PMID: 31763820; PMCID: PMC9484546.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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Soluble epoxide hydrolase inhibitor mediated analgesia lacks tolerance in rat models. Brain Res. 2020 02 01; 1728:146573.
Wagner KM, Atone J, Hammock BD. PMID: 31790682; PMCID: PMC6996511.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats. Kidney Blood Press Res. 2019; 44(6):1493-1505.
Certíková Chábová V, Kujal P, Vanourková Z, Škaroupková P, Sadowski J, Kompanowska-Jezierska E, Tesar V, Hammock B, Imig J, Maxová H, Cervenka L, Vanecková I. PMID: 31770762; PMCID: PMC10107074.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Ultrasensitive and rapid detection of ochratoxin A in agro-products by a nanobody-mediated FRET-based immunosensor. J Hazard Mater. 2020 04 05; 387:121678.
Tang Z, Liu X, Su B, Chen Q, Cao H, Yun Y, Xu Y, Hammock BD. PMID: 31753666; PMCID: PMC7990105.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCellsPHPublic Health
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COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence. FEBS J. 2020 04; 287(8):1666-1680.
Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX. PMID: 31646730; PMCID: PMC7174142.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. Lipids. 2020 01; 55(1):7-22.
Otoki Y, Metherel AH, Pedersen T, Yang J, Hammock BD, Bazinet RP, Newman JW, Taha AY. PMID: 31691988; PMCID: PMC7220815.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil samples based on a bifunctional fusion protein. Ecotoxicol Environ Saf. 2020 Jan 30; 188:109904.
Fu HJ, Wang Y, Xiao ZL, Wang H, Li ZF, Shen YD, Lei HT, Sun YM, Xu ZL, Hammock B. PMID: 31704326; PMCID: PMC7198468.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsPHPublic Health
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Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases. Prostaglandins Other Lipid Mediat. 2020 04; 147:106385.
Atone J, Wagner K, Hashimoto K, Hammock BD. PMID: 31698143; PMCID: PMC7067627.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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A Nanobody Against Cytotoxic T-Lymphocyte Associated Antigen-4 Increases the Anti-Tumor Effects of Specific CD8+ T Cells. J Biomed Nanotechnol. 2019 Nov 01; 15(11):2229-2239.
Tang Z, Mo F, Liu A, Duan S, Yang X, Liang L, Hou X, Yin S, Jiang X, Vasylieva N, Dong J, Barnych B, Hammock BD, Lu X. PMID: 31847937; PMCID: PMC9514155.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2. J Lipid Res. 2019 12; 60(12):1996-2005.
Rand AA, Rajamani A, Kodani SD, Harris TR, Schlatt L, Barnych B, Passerini AG, Hammock BD. PMID: 31641036; PMCID: PMC6889709.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. Biomolecules. 2019 10 11; 9(10).
Luo L, Wei XQ, Jia BZ, Yang JY, Shen YD, Hammock B, Dong JX, Wang H, Lei HT, Xu ZL. PMID: 31614550; PMCID: PMC6843301.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Microfluidic cap-to-dispense (μCD): a universal microfluidic-robotic interface for automated pipette-free high-precision liquid handling. Lab Chip. 2019 10 09; 19(20):3405-3415.
Wang J, Deng K, Zhou C, Fang Z, Meyer C, Deshpande KU, Li Z, Mi X, Luo Q, Hammock BD, Tan C, Chen Y, Pan T. PMID: 31501848; PMCID: PMC6785371.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Investigation of the Small Size of Nanobodies for a Sensitive Fluorescence Polarization Immunoassay for Small Molecules: 3-Phenoxybenzoic Acid, an Exposure Biomarker of Pyrethroid Insecticides as a Model. J Agric Food Chem. 2019 Oct 16; 67(41):11536-11541.
Wang Y, Li Z, Barnych B, Huo J, Wan D, Vasylieva N, Xu J, Li P, Liu B, Zhang C, Hammock BD. PMID: 31589045; PMCID: PMC7134064.
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PubMed Mentions:
6 Fields:
Translation:
HumansPHPublic Health
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Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. Front Pharmacol. 2019; 10:1118.
Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe DS, Kumar NG, Yang J, Hwang SH, Hammock BD, Sriramarao P, Rao SP. PMID: 31611798; PMCID: PMC6777353.
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PubMed Mentions:
9
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Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain. J Med Chem. 2019 09 26; 62(18):8443-8460.
Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. PMID: 31436984; PMCID: PMC7262789.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicol Appl Pharmacol. 2019 11 01; 382:114749.
Yang J, Bruun DA, Wang C, Wan D, McReynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. PMID: 31521729; PMCID: PMC6957308.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Cent Sci. 2019 Sep 25; 5(9):1614-1624.
Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. PMID: 31572788; PMCID: PMC6764161.
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PubMed Mentions:
16
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Fluorescent "Turn off-on" Small-Molecule-Monitoring Nanoplatform Based on Dendrimer-like Peptides as Competitors. ACS Appl Mater Interfaces. 2019 Sep 11; 11(36):33380-33389.
Chen H, Ding Y, Yang Q, Barnych B, González-Sapienza G, Hammock BD, Wang M, Hua X. PMID: 31433617; PMCID: PMC7059760.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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A label-free optical whole-cell Escherichia coli biosensor for the detection of pyrethroid insecticide exposure. Sci Rep. 2019 08 28; 9(1):12466.
Riangrungroj P, Bever CS, Hammock BD, Polizzi KM. PMID: 31462650; PMCID: PMC6713742.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. Bioorg Med Chem. 2019 10 15; 27(20):115078.
Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S. PMID: 31488357; PMCID: PMC6892585.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. ACS Chem Neurosci. 2019 09 18; 10(9):4018-4030.
Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. PMID: 31378059; PMCID: PMC7028313.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Highly Specific Monoclonal Antibody and Sensitive Quantum Dot Beads-Based Fluorescence Immunochromatographic Test Strip for Tebuconazole Assay in Agricultural Products. J Agric Food Chem. 2019 Aug 14; 67(32):9096-9103.
Wang Y, Xu J, Qiu Y, Li P, Liu B, Yang L, Barnych B, Hammock BD, Zhang C. PMID: 31356079; PMCID: PMC7069222.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsPHPublic Health
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A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain Behav Immun. 2019 10; 81:545-559.
Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock B, Vasylieva N, Hongsibsong S, Stern LJ, Crawford F, Mullan M, Abdullah L. PMID: 31325531; PMCID: PMC7155744.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model. Brain Behav Immun. 2019 10; 81:535-544.
Shen Y, Peng W, Chen Q, Hammock BD, Liu J, Li D, Yang J, Ding J, Wang X. PMID: 31306773; PMCID: PMC6873816.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Impact of the acute local inhibition of soluble epoxide hydrolase on diabetic skin microcirculatory dysfunction. Diab Vasc Dis Res. 2019 11; 16(6):523-529.
Savina Y, Duflot T, Bounoure F, Kotzki S, Thiebaut PA, Serreau PA, Skiba M, Picquenot JM, Cornic M, Morisseau C, Hammock B, Imbert L, Cracowski JL, Richard V, Roustit M, Bellien J. PMID: 31267765; PMCID: PMC7307659.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Inhibition of Pancreatic Carcinoma Growth Through Enhancing ω-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase. Anticancer Res. 2019 Jul; 39(7):3651-3660.
Xia R, Sun L, Liao J, Li H, You X, Xu D, Yang J, Hwang SH, Jones RD, Hammock B, Yang GY. PMID: 31262891; PMCID: PMC7117872.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice. Sci Rep. 2019 06 20; 9(1):8993.
Klocke J, Ulu A, Wu K, Rudolph B, Dragun D, Gollasch M, Schunck WH, Hammock BD, Riemekasten G, Enghard P. PMID: 31222024; PMCID: PMC6586931.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. J Clin Invest. 2019 06 17; 129(7):2964-2979.
Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, Sukhatme V, Hammock BD, Kieran MW, Huang S, Bhasin M, Serhan CN, Sukhatme VP. PMID: 31205032; PMCID: PMC6597207.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Cyclic peptide: a safe and effective alternative to synthetic aflatoxin B1-competitive antigens. Anal Bioanal Chem. 2019 Jul; 411(17):3881-3890.
Mukhtar H, Ma L, Pang Q, Zhou Y, Wang X, Xu T, Hammock BD, Wang J. PMID: 31152222.
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PubMed Mentions:
3 Fields:
Translation:
CellsPHPublic Health
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Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis. Front Pharmacol. 2019; 10:533.
McReynolds CB, Hwang SH, Yang J, Wan D, Wagner K, Morisseau C, Li D, Schmidt WK, Hammock BD. PMID: 31214021; PMCID: PMC6554663.
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PubMed Mentions:
19
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Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Front Pharmacol. 2019; 10:580.
Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. PMID: 31191316; PMCID: PMC6548860.
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PubMed Mentions:
2
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Computer-Aided Selective Optimization of Side Activities of Talinolol. ACS Med Chem Lett. 2019 Jun 13; 10(6):899-903.
Hiesinger K, Kramer JS, Achenbach J, Moser D, Weber J, Wittmann SK, Morisseau C, Angioni C, Geisslinger G, Kahnt AS, Kaiser A, Proschak A, Steinhilber D, Pogoryelov D, Wagner K, Hammock BD, Proschak E. PMID: 31223445; PMCID: PMC6580380.
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PubMed Mentions:
3
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N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase. Biochem Biophys Res Commun. 2019 07 12; 515(1):248-253.
Matsumoto N, Kataoka M, Hirosaki H, Morisseau C, Hammock BD, Suzuki E, Hasumi K. PMID: 31146915; PMCID: PMC7395850.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Impact of diabetes on male sexual function in streptozotocin-induced diabetic rats: Protective role of soluble epoxide hydrolase inhibitor. Biomed Pharmacother. 2019 Jul; 115:108897.
Minaz N, Razdan R, Hammock BD, Mujwar S, Goswami SK. PMID: 31102913; PMCID: PMC6893866.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly-horseradish peroxidase (PolyHRP). Electrophoresis. 2019 07; 40(12-13):1731-1739.
Mishra M, Tiwari S, Gunaseelan A, Li D, Hammock BD, Gomes AV. PMID: 31021001; PMCID: PMC7036291.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Front Pharmacol. 2019; 10:464.
Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. PMID: 31143115; PMCID: PMC6520522.
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PubMed Mentions:
13
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Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba. J Agric Food Chem. 2019 May 22; 67(20):5711-5719.
Huo J, Barnych B, Li Z, Wan D, Li D, Vasylieva N, Knezevic SZ, Osipitan OA, Scott JE, Zhang J, Hammock BD. PMID: 31042038; PMCID: PMC6873229.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCellsPHPublic Health
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Nanobody-based fluorescence resonance energy transfer immunoassay for noncompetitive and simultaneous detection of ochratoxin a and ochratoxin B. Environ Pollut. 2019 Aug; 251:238-245.
Tang Z, Liu X, Wang Y, Chen Q, Hammock BD, Xu Y. PMID: 31082608; PMCID: PMC7103568.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Addition of milk fat globule membrane-enriched supplement to a high-fat meal attenuates insulin secretion and induction of soluble epoxide hydrolase gene expression in the postprandial state in overweight and obese subjects. J Nutr Sci. 2019; 8:e16.
Beals E, Kamita SG, Sacchi R, Demmer E, Rivera N, Rogers-Soeder TS, Gertz ER, Van Loan MD, German JB, Hammock BD, Smilowitz JT, Zivkovic AM. PMID: 31080589; PMCID: PMC6498758.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes. Front Pharmacol. 2019; 10:288.
Pardeshi R, Bolshette N, Gadhave K, Arfeen M, Ahmed S, Jamwal R, Hammock BD, Lahkar M, Goswami SK. PMID: 31068802; PMCID: PMC6491817.
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PubMed Mentions:
12
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One-Step Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Fusion for Detection of Aflatoxin B1 in Cereal. J Agric Food Chem. 2019 May 08; 67(18):5221-5229.
Ren W, Li Z, Xu Y, Wan D, Barnych B, Li Y, Tu Z, He Q, Fu J, Hammock BD. PMID: 30883117; PMCID: PMC7792509.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsPHPublic Health
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Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations. Int J Biol Macromol. 2019 Jul 15; 133:1187-1193.
Liu ZB, Sun CP, Xu JX, Morisseau C, Hammock BD, Qiu F. PMID: 30980876.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Development of an immunoassay for the detection of carbaryl in cereals based on a camelid variable heavy-chain antibody domain. J Sci Food Agric. 2019 Jul; 99(9):4383-4390.
Liu Z, Wang K, Wu S, Wang Z, Ding G, Hao X, Li QX, Li J, Gee SJ, Hammock BD, Xu T. PMID: 30851058; PMCID: PMC7061733.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsPHPublic Health
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Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):7083-7088.
Ma M, Ren Q, Yang J, Zhang K, Xiong Z, Ishima T, Pu Y, Hwang SH, Toyoshima M, Iwayama Y, Hisano Y, Yoshikawa T, Hammock BD, Hashimoto K. PMID: 30890645; PMCID: PMC6452650.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsPHPublic Health
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Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats. Front Pharmacol. 2019; 10:159.
Hrdlicka J, Neckár J, Papoušek F, Husková Z, Kikerlová S, Vanourková Z, Vernerová Z, Akat F, Vašinová J, Hammock BD, Hwang SH, Imig JD, Falck JR, Cervenka L, Kolár F. PMID: 30881303; PMCID: PMC6406051.
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PubMed Mentions:
10
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One-step immunoassay for the insecticide carbaryl using a chicken single-chain variable fragment (scFv) fused to alkaline phosphatase. Anal Biochem. 2019 05 01; 572:9-15.
He J, Tao X, Wang K, Ding G, Li J, Li QX, Gee SJ, Hammock BD, Xu T. PMID: 30831096.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res. 2019 04 15; 79(8):1822-1830.
Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. PMID: 30803995; PMCID: PMC6467714.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5154-5159.
Luo Y, Wu MY, Deng BQ, Huang J, Hwang SH, Li MY, Zhou CY, Zhang QY, Yu HB, Zhao DK, Zhang G, Qin L, Peng A, Hammock BD, Liu JY. PMID: 30804206; PMCID: PMC6421466.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. Am J Physiol Gastrointest Liver Physiol. 2019 04 01; 316(4):G527-G538.
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y. PMID: 30789748; PMCID: PMC6483021.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. Int J Biol Macromol. 2019 May 15; 129:653-658.
de Oliveira GS, Adriani PP, Ribeiro JA, Morisseau C, Hammock BD, Dias MVB, Chambergo FS. PMID: 30771398; PMCID: PMC6447457.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Fluoroaromatic fragments on 1,3-disubstituted ureas enhance soluble epoxide hydrolase inhibition. J Fluor Chem. 2019 Apr; 220:48-53.
Burmistrov V, Morisseau C, D'yachenko V, Rybakov VB, Butov GM, Hammock BD. PMID: 32132741; PMCID: PMC7055688.
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PubMed Mentions:
2
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Development of a one-step immunoassay for triazophos using camel single-domain antibody-alkaline phosphatase fusion protein. Anal Bioanal Chem. 2019 Feb; 411(6):1287-1295.
Wang K, Liu Z, Ding G, Li J, Vasylieva N, Li QX, Li D, Gee SJ, Hammock BD, Xu T. PMID: 30706076; PMCID: PMC7153572.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsPHPublic Health
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A novel and simple imidazo[1,2-a]pyridin fluorescent probe for the sensitive and selective imaging of cysteine in living cells and zebrafish. Anal Chim Acta. 2019 Jun 13; 1058:155-165.
Zhu M, Wang L, Wu X, Na R, Wang Y, Li QX, Hammock BD. PMID: 30851849; PMCID: PMC7198451.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats. Front Pharmacol. 2019; 10:18.
Vacková Š, Kopkan L, Kikerlová S, Husková Z, Sadowski J, Kompanowska-Jezierska E, Hammock BD, Imig JD, Táborský M, Melenovský V, Cervenka L. PMID: 30728778; PMCID: PMC6351500.
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PubMed Mentions:
5
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Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1698-1703.
Gartung A, Yang J, Sukhatme VP, Bielenberg DR, Fernandes D, Chang J, Schmidt BA, Hwang SH, Zurakowski D, Huang S, Kieran MW, Hammock BD, Panigrahy D. PMID: 30647111; PMCID: PMC6358686.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Anal Chim Acta. 2019 May 30; 1057:106-113.
Vasylieva N, Kitamura S, Dong J, Barnych B, Hvorecny KL, Madden DR, Gee SJ, Wolan DW, Morisseau C, Hammock BD. PMID: 30832908; PMCID: PMC6426448.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCellsPHPublic Health
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Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity. Prostaglandins Other Lipid Mediat. 2019 02; 140:31-39.
Hiesinger K, Wagner KM, Hammock BD, Proschak E, Hwang SH. PMID: 30593866; PMCID: PMC6345559.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays. Anal Chem. 2019 01 15; 91(2):1532-1540.
Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. PMID: 30521755; PMCID: PMC7144541.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsPHPublic Health
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Competitive and noncompetitive immunoassays for the detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled peptides. Anal Bioanal Chem. 2019 Jan; 411(2):527-535.
Chen H, Yang Q, Ding Y, Vasylieva N, Bever CS, Hua X, Wang M, Hammock BD. PMID: 30478514; PMCID: PMC7263471.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
Soluble epoxide hydrolase inhibitor, APAU, protects dopaminergic neurons against rotenone induced neurotoxicity: Implications for Parkinson's disease. Neurotoxicology. 2019 01; 70:135-145.
Lakkappa N, Krishnamurthy PT, M D P, Hammock BD, Hwang SH. PMID: 30472438; PMCID: PMC6873230.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Brain oxylipin concentrations following hypercapnia/ischemia: effects of brain dissection and dissection time. J Lipid Res. 2019 03; 60(3):671-682.
Hennebelle M, Metherel AH, Kitson AP, Otoki Y, Yang J, Lee KSS, Hammock BD, Bazinet RP, Taha AY. PMID: 30463986; PMCID: PMC6399504.
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PubMed Mentions:
11 Fields:
Translation:
Animals
-
Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders. Prog Neurobiol. 2019 01; 172:23-39.
Zarriello S, Tuazon JP, Corey S, Schimmel S, Rajani M, Gorsky A, Incontri D, Hammock BD, Borlongan CV. PMID: 30447256; PMCID: PMC6993804.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei. Mol Biol Rep. 2019 Feb; 46(1):371-379.
de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS. PMID: 30426381; PMCID: PMC6426676.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. ACS Omega. 2018 Oct 31; 3(10):14076-14086.
Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. PMID: 30411058; PMCID: PMC6210075.
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PubMed Mentions:
14
-
Development of a Highly Sensitive Direct Competitive Fluorescence Enzyme Immunoassay Based on a Nanobody-Alkaline Phosphatase Fusion Protein for Detection of 3-Phenoxybenzoic Acid in Urine. J Agric Food Chem. 2018 Oct 31; 66(43):11284-11290.
Huo J, Li Z, Wan D, Li D, Qi M, Barnych B, Vasylieva N, Zhang J, Hammock BD. PMID: 30293433; PMCID: PMC6442738.
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PubMed Mentions:
12 Fields:
Translation:
HumansPHPublic Health
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Omega-3 PUFA attenuate mice myocardial infarction injury by emerging a protective eicosanoid pattern. Prostaglandins Other Lipid Mediat. 2018 11; 139:1-9.
Fang X, Cai W, Cheng Q, Ai D, Wang X, Hammock BD, Zhu Y, Zhang X. PMID: 30223037.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Development of a Nanobody-AviTag Fusion Protein and Its Application in a Streptavidin-Biotin-Amplified Enzyme-Linked Immunosorbent Assay for Ochratoxin A in Cereal. Anal Chem. 2018 09 04; 90(17):10628-10634.
Sun Z, Lv J, Liu X, Tang Z, Wang X, Xu Y, Hammock BD. PMID: 30092629; PMCID: PMC7307665.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A. Anal Bioanal Chem. 2018 Oct; 410(25):6633-6642.
He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T. PMID: 30066195; PMCID: PMC7105167.
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PubMed Mentions:
11 Fields:
Translation:
CellsPHPublic Health
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Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. J Hypertens. 2018 06; 36(6):1326-1341.
Cervenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vanourková Z, Alánová P, Kolár F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckár J. PMID: 29570510; PMCID: PMC7375140.
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PubMed Mentions:
19 Fields:
Translation:
Animals
-
Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res. 2018 Oct; 53(5):743-749.
Napimoga MH, Rocha EP, Trindade-da-Silva CA, Demasi APD, Martinez EF, Macedo CG, Abdalla HB, Bettaieb A, Haj FG, Clemente-Napimoga JT, Inceoglu B, Hammock BD. PMID: 29851077; PMCID: PMC6168335.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol. 2018 08; 94(2):834-841.
Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD. PMID: 29844231; PMCID: PMC6022802.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Adamantyl thioureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2018 07 15; 28(13):2302-2313.
Burmistrov V, Morisseau C, Pitushkin D, Karlov D, Fayzullin RR, Butov GM, Hammock BD. PMID: 29803731; PMCID: PMC6442743.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats. Prostaglandins Other Lipid Mediat. 2018 05; 136:84-89.
Minaz N, Razdan R, Hammock BD, Goswami SK. PMID: 29751149; PMCID: PMC6402559.
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PubMed Mentions:
13 Fields:
Translation:
Animals
-
Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):E5815-E5823.
Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K. PMID: 29735655; PMCID: PMC6016799.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):5283-5288.
Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G. PMID: 29717038; PMCID: PMC5960306.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling. Anal Chem. 2018 05 15; 90(10):6187-6192.
Lassabe G, Kramer K, Hammock BD, González-Sapienza G, González-Techera A. PMID: 29694028; PMCID: PMC5963685.
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PubMed Mentions:
7 Fields:
-
Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. Analyst. 2018 Apr 30; 143(9):2057-2065.
Cui X, Vasylieva N, Shen D, Barnych B, Yang J, He Q, Jiang Z, Zhao S, Hammock BD. PMID: 29629470; PMCID: PMC6449042.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J Med Chem. 2018 05 10; 61(9):4271.
Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 29701466; PMCID: PMC5949719.
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PubMed Mentions: Fields:
-
Celecoxib use and circulating oxylipins in a colon polyp prevention trial. PLoS One. 2018; 13(4):e0196398.
Martinez JA, Yang J, Wertheim BC, Roe DJ, Schriewer A, Lance P, Alberts DS, Hammock BD, Thompson PA. PMID: 29698447; PMCID: PMC5919576.
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PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem. 2018 04 26; 61(8):3541-3550.
Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. PMID: 29614224; PMCID: PMC5933862.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere. 2018 Jul; 203:467-473.
Bever CS, Rand AA, Nording M, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. PMID: 29635158; PMCID: PMC5915298.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci Rep. 2018 03 27; 8(1):5279.
Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC. PMID: 29588470; PMCID: PMC5869703.
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PubMed Mentions:
23 Fields:
Translation:
Animals
-
Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther. 2018 06; 365(3):467-475.
Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S. PMID: 29567865; PMCID: PMC5931432.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat. 2018 05; 136:90-95.
Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. PMID: 29567338; PMCID: PMC5970965.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula. Physiol Res. 2018 07 17; 67(3):401-415.
Kala P, Sedláková L, Škaroupková P, Kopkan L, Vanourková Z, Táborský M, Nishiyama A, Hwang SH, Hammock BD, Sadowski J, Melenovský V, Imig JD, Cervenka L. PMID: 29527914; PMCID: PMC6056335.
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PubMed Mentions:
11 Fields:
Translation:
Animals
-
Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney Blood Press Res. 2018; 43(2):329-349.
Certíková Chábová V, Kujal P, Škaroupková P, Varnourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesar V, Cervenka L. PMID: 29529602; PMCID: PMC5985203.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function. J Lipid Res. 2018 04; 59(4):684-695.
Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR. PMID: 29459481; PMCID: PMC5880498.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target. Neurosci Biobehav Rev. 2018 04; 87:56-66.
Swardfager W, Hennebelle M, Yu D, Hammock BD, Levitt AJ, Hashimoto K, Taha AY. PMID: 29407524; PMCID: PMC5860823.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Phage-Mediated Competitive Chemiluminescent Immunoassay for Detecting Cry1Ab Toxin by Using an Anti-Idiotypic Camel Nanobody. J Agric Food Chem. 2018 Jan 31; 66(4):950-956.
Qiu Y, Li P, Dong S, Zhang X, Yang Q, Wang Y, Ge J, Hammock BD, Zhang C, Liu X. PMID: 29293334; PMCID: PMC7314401.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCellsPHPublic Health
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Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation. J Leukoc Biol. 2018 07; 104(1):109-122.
Bastan I, Ge XN, Dileepan M, Greenberg YG, Guedes AG, Hwang SH, Hammock BD, Washabau RJ, Rao SP, Sriramarao P. PMID: 29345370; PMCID: PMC6020675.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett. 2018 02 15; 28(4):762-768.
Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. PMID: 29366648; PMCID: PMC5837813.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation. Proc Natl Acad Sci U S A. 2018 01 16; 115(3):613-618.
Yang YM, Sun D, Kandhi S, Froogh G, Zhuge J, Huang W, Hammock BD, Huang A. PMID: 29295935; PMCID: PMC5776989.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. J Alzheimers Dis. 2018; 62(4):1663-1681.
Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Erakovic Haber V, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L. PMID: 29504531; PMCID: PMC7065497.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide. Methods Mol Biol. 2018; 1730:123-133.
Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C. PMID: 29363071; PMCID: PMC5831730.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability. Bioorg Chem. 2018 02; 76:510-527.
Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD. PMID: 29310082; PMCID: PMC5837815.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. Mol Cancer Ther. 2018 02; 17(2):474-483.
Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, de Vere White RW, Pan CX. PMID: 29284644; PMCID: PMC5824635.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017 12 14; 552(7684):248-252.
Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I. PMID: 29211719; PMCID: PMC5828869.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal. 2018 Feb 05; 149:457-464.
Lakkappa N, Krishnamurthy PT, Yamjala K, Hwang SH, Hammock BD, Babu B. PMID: 29169114; PMCID: PMC5843369.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12608-12613.
Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY. PMID: 29109264; PMCID: PMC5703276.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis. J Vet Pharmacol Ther. 2018 Apr; 41(2):230-238.
Guedes AGP, Aristizabal F, Sole A, Adedeji A, Brosnan R, Knych H, Yang J, Hwang SH, Morisseau C, Hammock BD. PMID: 29067696; PMCID: PMC5920688.
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PubMed Mentions:
11 Fields:
Translation:
Animals
-
Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts. Anal Biochem. 2017 12 15; 539:81-89.
Kodani SD, Barthélemy M, Kamita SG, Hammock B, Morisseau C. PMID: 29054529; PMCID: PMC5696082.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies. Anal Chem. 2017 10 17; 89(20):11091-11097.
Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. PMID: 28942640; PMCID: PMC6459402.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice. Sci Rep. 2017 10 02; 7(1):12488.
Deol P, Fahrmann J, Yang J, Evans JR, Rizo A, Grapov D, Salemi M, Wanichthanarak K, Fiehn O, Phinney B, Hammock BD, Sladek FM. PMID: 28970503; PMCID: PMC5624939.
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PubMed Mentions:
29 Fields:
Translation:
Animals
-
COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor. Oncotarget. 2017 Oct 20; 8(50):87353-87363.
Li J, Zhou Y, Wang H, Gao Y, Li L, Hwang SH, Ji X, Hammock BD. PMID: 29152086; PMCID: PMC5675638.
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PubMed Mentions:
18 Fields:
-
Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:68-78.
Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. PMID: 28847566; PMCID: PMC5824649.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7545-E7553.
Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. PMID: 28827330; PMCID: PMC5594641.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2758-2765.
Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. PMID: 28757338; PMCID: PMC5873293.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Postprandial effect to decrease soluble epoxide hydrolase activity: roles of insulin and gut microbiota. J Nutr Biochem. 2017 11; 49:8-14.
Yang J, Oh YT, Wan D, Watanabe RM, Hammock BD, Youn JH. PMID: 28863368; PMCID: PMC5858941.
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PubMed Mentions:
12 Fields:
Translation:
Animals
-
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Sci Rep. 2017 06 28; 7(1):4342.
Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. PMID: 28659576; PMCID: PMC5489485.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. J Med Chem. 2017 07 13; 60(13):5392-5406.
Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRR, Rana S, Contreras JI, Sahoo R, Wan D, Young J, Dias Teixeira KL, Morisseau C, Halperin J, Hammock B, Natarajan A, Wang P, Chorev M, Aktas BH. PMID: 28590739; PMCID: PMC5567831.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases. Pharmacol Ther. 2017 Dec; 180:62-76.
Wagner KM, McReynolds CB, Schmidt WK, Hammock BD. PMID: 28642117; PMCID: PMC5677555.
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PubMed Mentions:
118 Fields:
Translation:
HumansAnimals
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Shexiang Baoxin pills promotes angiogenesis in myocardial infarction rats via up-regulation of 20-HETE-mediated endothelial progenitor cells mobilization. Atherosclerosis. 2017 08; 263:184-191.
Huang F, Liu Y, Yang X, Che D, Qiu K, Hammock BD, Wang J, Wang MH, Chen J, Huang H. PMID: 28646793; PMCID: PMC5828780.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats. Cardiovasc Ther. 2017 Jun; 35(3).
Islam O, Patil P, Goswami SK, Razdan R, Inamdar MN, Rizwan M, Mathew J, Inceoglu B, Stephen Lee KS, Hwang SH, Hammock BD. PMID: 28296232; PMCID: PMC5597338.
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PubMed Mentions:
14 Fields:
Translation:
Animals
-
Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472.
Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. PMID: 28411375; PMCID: PMC5808876.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury. FEBS J. 2017 07; 284(13):1970-1986.
Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG. PMID: 28485854; PMCID: PMC5515292.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs. Org Biomol Chem. 2017 May 23; 15(20):4308-4313.
Barnych B, Rand AA, Cajka T, Lee KSS, Hammock BD. PMID: 28470279; PMCID: PMC5527127.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers. Life Sci. 2017 Jul 01; 180:114-122.
Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD. PMID: 28522175; PMCID: PMC5659729.
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PubMed Mentions:
12 Fields:
Translation:
Animals
-
Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP? Anal Chem. 2017 06 06; 89(11):6248-6256.
Li D, Cui Y, Morisseau C, Gee SJ, Bever CS, Liu X, Wu J, Hammock BD, Ying Y. PMID: 28460522; PMCID: PMC5611449.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus. Front Microbiol. 2017; 8:831.
Fischer GJ, Bacon W, Yang J, Palmer JM, Dagenais T, Hammock BD, Keller NP. PMID: 28536571; PMCID: PMC5422543.
View in:
PubMed Mentions:
6
-
Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales. PLoS One. 2017; 12(5):e0176571.
Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD. PMID: 28472063; PMCID: PMC5417501.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L252-L266.
Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. PMID: 28473326; PMCID: PMC5582936.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice. Shock. 2017 05; 47(5):638-645.
Zhou Y, Liu T, Duan JX, Li P, Sun GY, Liu YP, Zhang J, Dong L, Lee KSS, Hammock BD, Jiang JX, Guan CX. PMID: 27753791; PMCID: PMC5382142.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L350-L359.
Kandhi S, Zhang B, Froogh G, Qin J, Alruwaili N, Le Y, Yang YM, Hwang SH, Hammock BD, Wolin MS, Huang A, Sun D. PMID: 28450284; PMCID: PMC5582931.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine. Anal Chem. 2017 05 16; 89(10):5612-5619.
Vasylieva N, Barnych B, Rand A, Inceoglu B, Gee SJ, Hammock BD. PMID: 28398746; PMCID: PMC5920647.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. Drug Metab Dispos. 2017 07; 45(7):712-720.
Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z. PMID: 28428366; PMCID: PMC5452678.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids. FASEB J. 2017 08; 31(8):3229-3239.
Fiala M, Kooij G, Wagner K, Hammock B, Pellegrini M. PMID: 28420693; PMCID: PMC5503712.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids. Proc Natl Acad Sci U S A. 2017 04 25; 114(17):4370-4375.
Rand AA, Barnych B, Morisseau C, Cajka T, Lee KSS, Panigrahy D, Hammock BD. PMID: 28396419; PMCID: PMC5410821.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure. 2017 05 02; 25(5):697-707.e4.
Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR. PMID: 28392259; PMCID: PMC5524515.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF. Chemosphere. 2017 Aug; 180:169-177.
Chu S, Baker MR, Leong G, Letcher RJ, Gee SJ, Hammock BD, Li QX. PMID: 28407546; PMCID: PMC5494263.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis. J Pharmacol Exp Ther. 2017 06; 361(3):408-416.
Trindade-da-Silva CA, Bettaieb A, Napimoga MH, Lee KSS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD. PMID: 28356494; PMCID: PMC5443319.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environ Int. 2017 06; 103:91-98.
Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. PMID: 28343720; PMCID: PMC5432128.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behav Brain Res. 2017 05 30; 326:69-76.
Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. PMID: 28259677; PMCID: PMC5409858.
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PubMed Mentions:
11 Fields:
Translation:
Animals
-
Lipidomic Analysis of Oxidized Fatty Acids in Plant and Algae Oils. J Agric Food Chem. 2017 Mar 08; 65(9):1941-1951.
Richardson CE, Hennebelle M, Otoki Y, Zamora D, Yang J, Hammock BD, Taha AY. PMID: 28157307; PMCID: PMC5581005.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study. Psychiatry Res. 2017 06; 252:94-101.
Hennebelle M, Otoki Y, Yang J, Hammock BD, Levitt AJ, Taha AY, Swardfager W. PMID: 28259037; PMCID: PMC5611448.
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PubMed Mentions:
22 Fields:
Translation:
Humans
-
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1382-1391.
Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. PMID: 28185955; PMCID: PMC5608514.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine. J Lipid Res. 2017 04; 58(4):798-808.
Wan D, Yang J, Barnych B, Hwang SH, Lee KSS, Cui Y, Niu J, Watsky MA, Hammock BD. PMID: 28148721; PMCID: PMC5392736.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. J Neurochem. 2017 03; 140(5):814-825.
Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A. PMID: 28002622; PMCID: PMC5310989.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes. Plast Reconstr Surg Glob Open. 2016 Dec; 4(12):e1151.
Supp DM, Hahn JM, McFarland KL, Combs KA, Lee KS, Inceoglu B, Wan D, Boyce ST, Hammock BD. PMID: 28293507; PMCID: PMC5222652.
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PubMed Mentions:
5
-
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators. Proc Natl Acad Sci U S A. 2017 01 03; 114(1):136-141.
Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM. PMID: 27980032; PMCID: PMC5224368.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansCells
-
Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorg Med Chem Lett. 2017 02 01; 27(3):620-625.
Hwang SH, Wagner K, Xu J, Yang J, Li X, Cao Z, Morisseau C, Lee KS, Hammock BD. PMID: 28025003; PMCID: PMC5584617.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Effects of high-fat diet on plasma profiles of eicosanoid metabolites in mice. Prostaglandins Other Lipid Mediat. 2016 12; 127:9-13.
Wang W, Yang J, Yang H, Sanidad KZ, Hammock BD, Kim D, Zhang G. PMID: 27913146; PMCID: PMC5628263.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Lipidomic profiling of high-fat diet-induced obesity in mice: Importance of cytochrome P450-derived fatty acid epoxides. Obesity (Silver Spring). 2017 01; 25(1):132-140.
Wang W, Yang J, Qi W, Yang H, Wang C, Tan B, Hammock BD, Park Y, Kim D, Zhang G. PMID: 27891824; PMCID: PMC5182168.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Nanobody-based enzyme immunoassay for ochratoxin A in cereal with high resistance to matrix interference. Talanta. 2017 Mar 01; 164:154-158.
Liu X, Tang Z, Duan Z, He Z, Shu M, Wang X, Gee SJ, Hammock BD, Xu Y. PMID: 28107910; PMCID: PMC5862147.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsPHPublic Health
-
Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Arch Biochem Biophys. 2017 Jan 01; 613:1-11.
Lee KS, Henriksen NM, Ng CJ, Yang J, Jia W, Morisseau C, Andaya A, Gilson MK, Hammock BD. PMID: 27983948; PMCID: PMC5172606.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents. Mitochondrion. 2016 Nov; 31:79-83.
Datta S, Sahdeo S, Gray JA, Morriseau C, Hammock BD, Cortopassi G. PMID: 27717841; PMCID: PMC5108672.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere. 2017 Jan; 166:511-520.
Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. PMID: 27710886; PMCID: PMC5560107.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use. J Ethnopharmacol. 2016 Dec 24; 194:475-482.
Liu JY, Morisseau C, Huang H, Hammock BD. PMID: 27702689; PMCID: PMC5584568.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16; 262:92-99.
Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. PMID: 27659731; PMCID: PMC5096949.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Epoxy fatty acids mediate analgesia in murine diabetic neuropathy. Eur J Pain. 2017 03; 21(3):456-465.
Wagner K, Lee KS, Yang J, Hammock BD. PMID: 27634339; PMCID: PMC5300894.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis. J Nutr Biochem. 2016 12; 38:93-101.
Harris TR, Kodani S, Yang J, Imai DM, Hammock BD. PMID: 27732914; PMCID: PMC5102762.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis. Equine Vet J. 2017 May; 49(3):345-351.
Guedes A, Galuppo L, Hood D, Hwang SH, Morisseau C, Hammock BD. PMID: 27338788; PMCID: PMC5580818.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCellsCTClinical Trials
-
Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol. 2016 Nov 15; 223:923-935.
Ghosh R, Goswami SK, Feitoza LFBB, Hammock B, Gomes AV. PMID: 27589040; PMCID: PMC5076377.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice. J Mol Cell Cardiol. 2016 09; 98:128-37.
Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan LM, Hammock BD, Ai D, Zhu Y. PMID: 27496380; PMCID: PMC5559083.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136.
Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. PMID: 27467073; PMCID: PMC5063690.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
-
A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat. Prostaglandins Other Lipid Mediat. 2016 09; 125:40-7.
Hye Khan MA, Hwang SH, Sharma A, Corbett JA, Hammock BD, Imig JD. PMID: 27432695; PMCID: PMC5035206.
View in:
PubMed Mentions:
28 Fields:
Translation:
Animals
-
Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1919-27.
Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellström A, Hammock BD, Zeldin DC, Smith LE. PMID: 27417579; PMCID: PMC5010176.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
-
Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. Insect Biochem Mol Biol. 2016 09; 76:62-69.
Xu J, Morisseau C, Yang J, Lee KSS, Kamita SG, Hammock BD. PMID: 27369469; PMCID: PMC5010450.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury. Front Pharmacol. 2016; 7:133.
Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM. PMID: 27375480; PMCID: PMC4896112.
View in:
PubMed Mentions:
14
-
Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders. Med Hypotheses. 2016 Aug; 93:161-5.
Lakkappa N, Krishnamurthy PT, Hammock BD, Velmurugan D, Bharath MM. PMID: 27372879; PMCID: PMC4985172.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Erratum to: Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 06; 364(3):675.
Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26946414.
View in:
PubMed Mentions:
2 Fields:
-
Inhibition of soluble epoxide hydrolase as a novel approach to high dose diazepam induced hypotension. J Clin Toxicol. 2016 Jun; 6(3).
Ulu A, Inceoglu B, Yang J, Singh V, Vito S, Wulff H, Hammock BD. PMID: 28255523; PMCID: PMC5328659.
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PubMed Mentions:
12
-
VHH antibodies: emerging reagents for the analysis of environmental chemicals. Anal Bioanal Chem. 2016 Sep; 408(22):5985-6002.
Bever CS, Dong JX, Vasylieva N, Barnych B, Cui Y, Xu ZL, Hammock BD, Gee SJ. PMID: 27209591; PMCID: PMC4983233.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsPHPublic Health
-
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. Int J Mol Sci. 2016 May 18; 17(5).
Sharma A, Hye Khan MA, Levick SP, Lee KS, Hammock BD, Imig JD. PMID: 27213332; PMCID: PMC4881572.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
-
3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats. Toxicol Sci. 2016 08; 152(2):309-22.
Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. PMID: 27208083; PMCID: PMC4960907.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins Leukot Essent Fatty Acids. 2018 11; 138:71-80.
Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE. PMID: 27282298; PMCID: PMC5106341.
View in:
PubMed Mentions:
32 Fields:
Translation:
Animals
-
Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorg Med Chem. 2016 10 15; 24(20):4801-4811.
Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. PMID: 27320659; PMCID: PMC5053890.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa. J Med Chem. 2016 05 26; 59(10):4790-9.
Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C. PMID: 27120257; PMCID: PMC4957648.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 May; 9(5).
Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, Young JN, Yamoah EN, Haj F, Ripplinger CM, Hammock BD, Chiamvimonvat N. PMID: 27162031; PMCID: PMC4869994.
View in:
PubMed Mentions:
29 Fields:
Translation:
Animals
-
Quantification of GST and esterase activities in pyrethrin-resistant mosquitoes using pyrethroid-like fluorescent substrates. Int J Pest Manag. 2016; 62(4):276-283.
Kamita SG, Mulligan S, Cornel AJ, Hammock BD. PMID: 28736488; PMCID: PMC5516934.
View in:
PubMed Mentions:
2
-
11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. J Mol Cell Cardiol. 2016 05; 94:180-188.
Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. PMID: 27079253; PMCID: PMC4972711.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Anti-idiotypic nanobody-alkaline phosphatase fusion proteins: Development of a one-step competitive enzyme immunoassay for fumonisin B1 detection in cereal. Anal Chim Acta. 2016 Jun 14; 924:53-59.
Shu M, Xu Y, Liu X, Li Y, He Q, Tu Z, Fu J, Gee SJ, Hammock BD. PMID: 27181644.
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PubMed Mentions:
17 Fields:
-
Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61.
Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. PMID: 26937944; PMCID: PMC4821808.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther. 2016 06; 357(3):529-36.
Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. PMID: 26989141; PMCID: PMC4885505.
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PubMed Mentions:
31 Fields:
Translation:
Animals
-
Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):E1944-52.
Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. PMID: 26976569; PMCID: PMC4822604.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimals
-
Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? Mol Pain. 2016; 12.
Ramsden CE, Ringel A, Majchrzak-Hong SF, Yang J, Blanchard H, Zamora D, Loewke JD, Rapoport SI, Hibbeln JR, Davis JM, Hammock BD, Taha AY. PMID: 27030719; PMCID: PMC4955998.
View in:
PubMed Mentions:
28 Fields:
Translation:
Animals
-
Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates. Drug Metab Dispos. 2016 May; 44(5):771-80.
Zhao Y, Wan D, Yang J, Hammock BD, Ortiz de Montellano PR. PMID: 26936974; PMCID: PMC4851306.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Addition of DHA Synergistically Enhances the Efficacy of Regorafenib for Kidney Cancer Therapy. Mol Cancer Ther. 2016 05; 15(5):890-8.
Kim J, Ulu A, Wan D, Yang J, Hammock BD, Weiss RH. PMID: 26921392; PMCID: PMC4873345.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 2016 Mar; 92:30-40.
Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C. PMID: 26812119; PMCID: PMC5008453.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (Lond). 2016 Feb; 11(4):377-90.
Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. PMID: 26786134; PMCID: PMC4910953.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. J Ocul Biol. 2016 Jan; 4(1).
McLellan GJ, Aktas Z, Hennes-Beean E, Kolb AW, Larsen IV, Schmitz EJ, Clausius HR, Yang J, Hwang SH, Morisseau C, Inceoglu B, Hammock BD, Brandt CR. PMID: 28066796; PMCID: PMC5218821.
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PubMed Mentions:
3
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Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery. J Lipid Res. 2016 Mar; 57(3):492-8.
Akintoye E, Wu JH, Hou T, Song X, Yang J, Hammock B, Mozaffarian D. PMID: 26749073; PMCID: PMC4766998.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-KrasG¹²D/Pdx-1-Cre Mice. Anticancer Res. 2016 Jan; 36(1):27-37.
Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY. PMID: 26722025; PMCID: PMC4793710.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. PLoS One. 2015; 10(12):e0144996.
Berthelot CC, Kamita SG, Sacchi R, Yang J, Nording ML, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Hammock BD, Zivkovic AM. PMID: 26672987; PMCID: PMC4681469.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Lett. 2016 Feb 28; 371(2):187-93.
Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY. PMID: 26683769; PMCID: PMC4738175.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays. Anal Chem. 2015 Dec 01; 87(23):11907-14.
Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever CS, Lee KS, Morisseau C, Leizagoyen C, Gee S, Hammock BD, González-Sapienza G. PMID: 26544909; PMCID: PMC4666776.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model. Toxicol Appl Pharmacol. 2015 Dec 15; 289(3):419-27.
Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. PMID: 26522832; PMCID: PMC4666679.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2015 Dec 01; 25(23):5514-9.
Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. PMID: 26520661; PMCID: PMC4654407.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase. Bioorg Med Chem. 2015 Nov 15; 23(22):7199-210.
Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K. PMID: 26507430.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Effects of juvenile hormone (JH) analog insecticides on larval development and JH esterase activity in two spodopterans. Pestic Biochem Physiol. 2016 Mar; 128:30-6.
El-Sheikh el-SA, Kamita SG, Hammock BD. PMID: 26969437.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochem Pharmacol. 2015 Dec 15; 98(4):718-31.
Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. PMID: 26494425; PMCID: PMC4656071.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Soluble epoxide hydrolase is involved in the development of atherosclerosis and arterial neointima formation by regulating smooth muscle cell migration. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1894-903.
Wang Q, Huo L, He J, Ding W, Su H, Tian D, Welch C, Hammock BD, Ai D, Zhu Y. PMID: 26453326.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Aerobic exercise-based rehabilitation affects the activities of progenitor endothelial cells through EETs pathway. Med Hypotheses. 2015 Dec; 85(6):1037-8.
Deng LM, Li XP, Xu DY, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 26454561; PMCID: PMC5003087.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Vitamin D in Tear Fluid. Invest Ophthalmol Vis Sci. 2015 Sep; 56(10):5880-7.
Lu X, Elizondo RA, Nielsen R, Christensen EI, Yang J, Hammock BD, Watsky MA. PMID: 26348637; PMCID: PMC4566401.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell Tissue Res. 2016 02; 363(2):399-409.
Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. PMID: 26310139; PMCID: PMC4738109.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Anal Chim Acta. 2015 Aug 26; 890:150-6.
Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. PMID: 26347177; PMCID: PMC4791039.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem. 2015 Sep; 407(24):7263-73.
Ranganathan A, Gee SJ, Hammock BD. PMID: 26255293; PMCID: PMC4580343.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environ Sci Technol. 2015 Aug 18; 49(16):10038-47.
Vasylieva N, Ahn KC, Barnych B, Gee SJ, Hammock BD. PMID: 26196357; PMCID: PMC4605820.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem. 2015 Sep; 407(24):7275-83.
Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD. PMID: 26229025; PMCID: PMC4573264.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. Am J Physiol Renal Physiol. 2015 Sep 15; 309(6):F492-8.
Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock B, Bell PD, Guay-Woodford LM, Weiss RH. PMID: 26155843; PMCID: PMC4572393.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9082-7.
Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. PMID: 26150506; PMCID: PMC4517273.
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PubMed Mentions:
82 Fields:
Translation:
Animals
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Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew Chem Int Ed Engl. 2015 Aug 17; 54(34):9881-5.
Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. PMID: 26136396; PMCID: PMC4556431.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat. 2015 Sep; 121(Pt A):131-7.
Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. PMID: 26117215; PMCID: PMC4688279.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimals