Christophe H Morisseau

Title(s)Professional Researcher, Entomology
SchoolAgriculture
AddressOne Shield Avenue
CA 95616
Phone530-752-6571
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Strategies for the Immobilization and Signal Amplification of a Double Nanobody Sandwich ELISA for Human Microsomal Epoxide Hydrolase. Anal Chem. 2024 Nov 22. He Q, Pan B, McCoy M, Pan J, Xu Z, Morisseau C, Sun G, Li D, Hammock BD. PMID: 39576950.
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    2. In Vivo-Active Soluble Epoxide Hydrolase-Targeting PROTACs with Improved Potency and Stability. ACS Med Chem Lett. 2024 Nov 14; 15(11):1891-1898. Nakane K, Morisseau C, Dowker-Key PD, Benitez G, Aguilan JT, Nagai E, Sidoli S, Hammock BD, Bettaieb A, Shinoda K, Kitamura S. PMID: 39563815; PMCID: PMC11571017.
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    3. Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models. bioRxiv. 2024 Aug 31. Tang C, Border JJ, Zhang H, Gregory A, Bai S, Fang X, Liu Y, Wang S, Hwang SH, Gao W, Morgan GC, Smith J, Bunn D, Cantwell C, Wagner KM, Morisseau C, Yang J, Shin SM, O'Herron P, Bagi Z, Filosa JA, Dong Y, Yu H, Hammock BD, Roman RJ, Fan F. PMID: 39257786; PMCID: PMC11383657.
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    4. Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabolites in murine livers via lipidomic profiling. Sci Rep. 2024 08 19; 14(1):19135. Sule RO, Morisseau C, Yang J, Hammock BD, Gomes AV. PMID: 39160161; PMCID: PMC11333623.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain. Int J Mol Sci. 2024 Aug 14; 25(16). Babkov D, Eliseeva N, Adzhienko K, Bagmetova V, Danilov D, McReynolds CB, Morisseau C, Hammock BD, Burmistrov V. PMID: 39201526; PMCID: PMC11354909.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. 4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats. BBA Adv. 2024; 6:100119. Carr D, Chin C, Chacon T, Herawi MK, Gonzalez M, West R, Morisseau C, Hammock BD, Pecic S, Kandasamy R. PMID: 39246819; PMCID: PMC11379592.
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    7. In vivo -Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability. bioRxiv. 2024 Jul 24. Nakane K, Morisseau C, Dowker-Key PD, Benitez G, Aguilan JT, Nagai E, Sidoli S, Hammock BD, Bettaieb A, Shinoda K, Kitamura S. PMID: 39211216; PMCID: PMC11361158.
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    8. Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain. J Med Chem. 2024 Aug 08; 67(15):12887-12911. Xu H, Chen Y, Tong H, Chen L, Morisseau C, Zhou Z, Zhuang J, Song C, Cai P, Liu Z, Hammock BD, Chen G. PMID: 39033411; PMCID: PMC11412156.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    9. Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations. Heliyon. 2024 Jun 15; 10(11):e32262. Angelia J, Duong L, Yun F, Mesic A, Yuan C, Carr D, Gunari S, Hudson PK, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 38912512; PMCID: PMC11190605.
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    10. Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS-CoV-2-infected mice. FASEB J. 2024 May 31; 38(10):e23692. Edin ML, Gruzdev A, Graves JP, Lih FB, Morisseau C, Ward JM, Hammock BD, Bosio CM, Zeldin DC. PMID: 38786655; PMCID: PMC11141730.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. The Role of Autophagy in Human Uveal Melanoma and the Development of Potential Disease Biomarkers and Novel Therapeutic Paradigms. Biomedicines. 2024 Feb 19; 12(2). Wang JZ, Paulus P, Niu Y, Zhu L, Morisseau C, Rawling T, Murray M, Hammock BD, Zhou F. PMID: 38398064; PMCID: PMC10886749.
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    12. Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality. J Med Chem. 2024 02 08; 67(3):2095-2117. Chen Y, Sun J, Tong H, Wang J, Cao R, Xu H, Chen L, Morisseau C, Zhang M, Shi Y, Han C, Zhuang J, Jing Y, Liu Z, Hammock BD, Chen G. PMID: 38236416; PMCID: PMC11308793.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    13. Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy. J Enzyme Inhib Med Chem. 2023 Dec; 38(1):2274797. Burmistrov VV, Morisseau C, Danilov DV, Gladkikh BP, D'yachenko VS, Zefirov NA, Zefirova ON, Butov GM, Hammock BD. PMID: 37975322; PMCID: PMC11003477.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water. Anal Bioanal Chem. 2024 Jan; 416(1):141-149. Wu S, Tian J, Xue X, Ma F, Li QX, Morisseau C, Hammock BD, Xu T. PMID: 37934249; PMCID: PMC10829939.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    15. Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress. Biomed Pharmacother. 2023 Dec; 168:115667. Peyman M, Barroso E, Turcu AL, Estrany F, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, Palomer X, Galdeano C, Vázquez S, Vázquez-Carrera M. PMID: 37826940; PMCID: PMC10786198.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    16. The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase. Int J Mol Sci. 2023 Sep 28; 24(19). He Q, McCoy MR, Qi M, Morisseau C, Yang H, Xu C, Shey R, Goodman MC, Zhao S, Hammock BD. PMID: 37834144; PMCID: PMC10572367.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins during their inducible expression in Escherichia coli. Anal Bioanal Chem. 2023 Sep; 415(23):5563-5574. Yin Z, He Q, Yang H, Morisseau C, El-Sheikh EA, Li D, Hammock BD. PMID: 37505234; PMCID: PMC10473979.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    18. Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity. Int J Mol Sci. 2023 Jun 28; 24(13). Oh YT, Yang J, Morisseau C, He Q, Hammock B, Youn JH. PMID: 37445935; PMCID: PMC10341844.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury. J Hazard Mater. 2023 09 15; 458:131890. Zhang J, Zhang WH, Morisseau C, Zhang M, Dong HJ, Zhu QM, Huo XK, Sun CP, Hammock BD, Ma XC. PMID: 37406527; PMCID: PMC10699546.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    20. Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity. Int J Mol Sci. 2023 Jun 09; 24(12). Wang W, Wang Y, Wagner KM, Lee RD, Hwang SH, Morisseau C, Wulff H, Hammock BD. PMID: 37373086; PMCID: PMC10298596.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    21. Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act as biomarkers and mechanisms for disease progression. Pharmacol Ther. 2023 08; 248:108454. McReynolds C, Hammock B, Morisseau C. PMID: 37268114; PMCID: PMC10529401.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    22. Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA. J Pharm Anal. 2023 Sep; 13(9):1013-1023. Yang H, Qi M, He Q, Hwang SH, Yang J, McCoy M, Morisseau C, Zhao S, Hammock BD. PMID: 37842656; PMCID: PMC10568103.
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    23. Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits. J Chem Inf Model. 2023 05 22; 63(10):3209-3225. Vázquez J, Ginex T, Herrero A, Morisseau C, Hammock BD, Luque FJ. PMID: 37141492; PMCID: PMC10207366.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    24. Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice. Biochem Biophys Res Commun. 2023 07 30; 667:64-72. Kulkarni R, Mehta R, Goswami SK, Hammock BD, Morisseau C, Hwang SH, Mallappa O, Azeemuddin MM, Rafiq M, S N M. PMID: 37209564; PMCID: PMC10849156.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    25. Mix-and-Read Nanobody-Based Sandwich Homogeneous Split-Luciferase Assay for the Rapid Detection of Human Soluble Epoxide Hydrolase. Anal Chem. 2023 04 11; 95(14):6038-6045. He Q, McCoy MR, Yang H, Lin M, Cui X, Zhao S, Morisseau C, Li D, Hammock BD. PMID: 36972550; PMCID: PMC10335774.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    26. PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction. ACS Chem Biol. 2023 04 21; 18(4):884-896. Wang Y, Morisseau C, Takamura A, Wan D, Li D, Sidoli S, Yang J, Wolan DW, Hammock BD, Kitamura S. PMID: 36947831; PMCID: PMC10586715.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    27. Development of a Genetically Encoded Magnetic Platform in Magnetospirillum gryphiswaldense MSR-1 for Downstream Processing of Protein Expression System. Res Sq. 2023 Mar 13. Wu S, Tian J, Xue X, Tang Z, Huang Z, Hammock BD, Morisseau C, Li QX, Xu T. PMID: 36993437; PMCID: PMC10055543.
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    28. Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon. Int J Mol Sci. 2023 Feb 26; 24(5). Wang W, Wagner KM, Wang Y, Singh N, Yang J, He Q, Morisseau C, Hammock BD. PMID: 36901999; PMCID: PMC10003560.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    29. Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury. ACS Cent Sci. 2023 Mar 22; 9(3):440-456. Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC. PMID: 36968547; PMCID: PMC10037491.
      View in: PubMed   Mentions: 10  
    30. Inhibition of Soluble Epoxide Hydrolase Does Not Promote or Aggravate Pulmonary Hypertension in Rats. Cells. 2023 02 20; 12(4). Leuillier M, Platel V, Tu L, Feugray G, Thuillet R, Groussard D, Messaoudi H, Ottaviani M, Chelgham M, Nicol L, Mulder P, Humbert M, Richard V, Morisseau C, Brunel V, Duflot T, Guignabert C, Bellien J. PMID: 36831332; PMCID: PMC9954493.
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    31. Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases. J Med Chem. 2023 02 23; 66(4):2979-3009. Chen Y, Chen L, Xu H, Cao R, Morisseau C, Zhang M, Shi Y, Hammock BD, Wang J, Zhuang J, Liu Z, Chen G. PMID: 36689364; PMCID: PMC9974930.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    32. Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors. J Fluor Chem. 2023 Feb; 266. Burmistrov VV, Morisseau C, Shkineva TK, Danilov DV, Gladkikh B, Butov GM, Fayzullin RR, Dutova TY, Hammock BD, Dalinger IL. PMID: 37638129; PMCID: PMC10457016.
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    33. Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer. Oncogene. 2023 02; 42(9):693-707. Yang JC, Xu P, Ning S, Wasielewski LJ, Adomat H, Hwang SH, Morisseau C, Gleave M, Corey E, Gao AC, Lara PN, Evans CP, Hammock BD, Liu C. PMID: 36596844; PMCID: PMC9975039.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    34. Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury. Int J Biol Sci. 2023; 19(1):294-310. Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC. PMID: 36594097; PMCID: PMC9760444.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    35. Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior. Prostaglandins Other Lipid Mediat. 2023 02; 164:106702. Angelia J, Weng X, Solomatov A, Chin C, Fernandez A, Hudson PK, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 36529320; PMCID: PMC9879382.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    36. Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner. Ecotoxicol Environ Saf. 2023 Jan 01; 249:114417. Wang W, Wang Y, Yang J, Wagner KM, Hwang SH, Cheng J, Singh N, Edwards P, Morisseau C, Zhang G, Panigrahy D, Hammock BD. PMID: 36525946; PMCID: PMC9879385.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    37. Ureas derived from camphor and fenchone reveal enantiomeric preference of human soluble epoxide hydrolase. Results Chem. 2022 Jan; 4. Burmistrov V, Morisseau C, Pitushkin D, Fayzullin RR, Karlov D, Vernigora A, Kuznetsov Y, Abbas SMH, Butov GM, Hammock BD. PMID: 37601415; PMCID: PMC10438916.
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    38. Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors. J Med Chem. 2022 10 27; 65(20):13660-13680. Codony S, Entrena JM, Calvó-Tusell C, Jora B, González-Cano R, Osuna S, Corpas R, Morisseau C, Pérez B, Barniol-Xicota M, Griñán-Ferré C, Pérez C, Rodríguez-Franco MI, Martínez AL, Loza MI, Pallàs M, Verhelst SHL, Sanfeliu C, Feixas F, Hammock BD, Brea J, Cobos EJ, Vázquez S. PMID: 36222708; PMCID: PMC9620236.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    39. Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women. Int J Mol Sci. 2022 Oct 05; 23(19). Nguyen N, Morisseau C, Li D, Yang J, Lam E, Woodside DB, Hammock BD, Shih PB. PMID: 36233100; PMCID: PMC9569757.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety. Int J Mol Sci. 2022 Sep 14; 23(18). Burmistrov V, Morisseau C, Babkov DA, Golubeva T, Pitushkin D, Sokolova EV, Vasipov V, Kuznetsov Y, Bazhenov SV, Novoyatlova US, Bondarev NA, Manukhov IV, Osipova V, Berberova N, Spasov AA, Butov GM, Hammock BD. PMID: 36142611; PMCID: PMC9501280.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    41. The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms. Prostaglandins Other Lipid Mediat. 2022 10; 162:106662. Matsumoto N, Singh N, Lee KS, Barnych B, Morisseau C, Hammock BD. PMID: 35779854; PMCID: PMC9530012.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    42. Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary tracer. Anal Methods. 2022 05 13; 14(18):1810-1819. Singh N, Li D, McReynolds CB, Morisseau C, Hammock BD. PMID: 35481804; PMCID: PMC9116231.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. The Role of Hydrolases in Biology and Xenobiotics Metabolism. Int J Mol Sci. 2022 Apr 28; 23(9). Morisseau C. PMID: 35563260; PMCID: PMC9105290.
      View in: PubMed   Mentions: 3     Fields:    
    44. CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury. J Adv Res. 2023 01; 43:163-174. Leuillier M, Duflot T, Ménoret S, Messaoudi H, Djerada Z, Groussard D, Denis RGP, Chevalier L, Karoui A, Panthu B, Thiébaut PA, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Féliu C, Peyret H, Nicol L, Henry JP, Renet S, Mulder P, Wan D, Tesson L, Heslan JM, Duché A, Jacques S, Ziegler F, Brunel V, Rautureau GJP, Monteil C, do Rego JL, do Rego JC, Afonso C, Hammock B, Madec AM, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. PMID: 36585106; PMCID: PMC9811321.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    45. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022 03 24; 65(6):4909-4925. Codony S, Pont C, Griñán-Ferré C, Di Pede-Mattatelli A, Calvó-Tusell C, Feixas F, Osuna S, Jarné-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Pérez B, Bartra C, Sanfeliu C, Juárez-Jiménez J, Morisseau C, Hammock BD, Pallàs M, Vázquez S, Muñoz-Torrero D. PMID: 35271276; PMCID: PMC8958510.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    46. Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model. Proc Natl Acad Sci U S A. 2022 03 01; 119(9). Sun CP, Zhou JJ, Yu ZL, Huo XK, Zhang J, Morisseau C, Hammock BD, Ma XC. PMID: 35217618; PMCID: PMC8892522.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    47. A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry. Molecules. 2022 Jan 03; 27(1). Wan D, Morisseau C, Hammock BD, Yang J. PMID: 35011515; PMCID: PMC8747065.
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    48. 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity. Pharmaceuticals (Basel). 2021 Dec 17; 14(12). Martín-López J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vázquez S. PMID: 34959721; PMCID: PMC8703317.
      View in: PubMed   Mentions: 2  
    49. Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. Front Pharmacol. 2021; 12:778470. Wagner KM, Yang J, Morisseau C, Hammock BD. PMID: 34975481; PMCID: PMC8719166.
      View in: PubMed   Mentions: 2  
    50. New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. Chem Res Toxicol. 2021 12 20; 34(12):2579-2591. Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD. PMID: 34817988; PMCID: PMC8853703.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    51. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021 12 01; 51:116507. Wilt S, Kodani S, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S. PMID: 34794001; PMCID: PMC8900675.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development. Molecules. 2021 Aug 19; 26(16). McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. PMID: 34443621; PMCID: PMC8399023.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    53. Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway. Food Chem Toxicol. 2021 Oct; 156:112516. Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC. PMID: 34411643; PMCID: PMC8889936.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    54. EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. Elife. 2021 08 03; 10. Gautheron J, Morisseau C, Chung WK, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Fève B, Vigouroux C, Andreelli F, Jeru I. PMID: 34342583; PMCID: PMC8331186.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    55. Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice. Int J Mol Sci. 2021 Jul 31; 22(15). Yang Y, Xu X, Wu H, Yang J, Chen J, Morisseau C, Hammock BD, Bettaieb A, Zhao L. PMID: 34361032; PMCID: PMC8347952.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    56. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome. Drug Metab Dispos. 2021 09; 49(9):810-821. Fang Y, Johnson H, Anderl JL, Muchamuel T, McMinn D, Morisseau C, Hammock BD, Kirk C, Wang J. PMID: 34234005.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    57. Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis. Eur J Med Chem. 2021 Nov 05; 223:113678. Du F, Sun W, Morisseau C, Hammock BD, Bao X, Liu Q, Wang C, Zhang T, Yang H, Zhou J, Xiao W, Liu Z, Chen G. PMID: 34218083; PMCID: PMC8877601.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    58. Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicity. Chem Biol Drug Des. 2021 07; 98(1):102-113. Jones Lipinski RA, Thillier Y, Morisseau C, Sebastiano CS, Smith BC, Hall CD, Katritzky AR. PMID: 33955172; PMCID: PMC8281356.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    59. Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss. Free Radic Biol Med. 2021 08 20; 172:48-57. Koike S, Hsu MF, Bettaieb A, Chu B, Matsumoto N, Morisseau C, Havel PJ, Huising MO, Hammock BD, Haj FG. PMID: 34038767; PMCID: PMC9901526.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    60. Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. Antioxidants (Basel). 2021 May 20; 10(5). Mavangira V, Kuhn MJ, Abuelo A, Morisseau C, Hammock BD, Sordillo LM. PMID: 34065244; PMCID: PMC8161397.
      View in: PubMed   Mentions: 3  
    61. Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. Int J Mol Sci. 2021 May 08; 22(9). Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD. PMID: 34066758; PMCID: PMC8125816.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    62. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. J Med Chem. 2021 05 13; 64(9):5429-5446. Codony S, Calvó-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Pérez C, Rodríguez-Franco MI, Pizarro-Delgado J, Corpas R, Griñán-Ferré C, Pallàs M, Sanfeliu C, Vázquez-Carrera M, Hammock BD, Feixas F, Vázquez S. PMID: 33945278; PMCID: PMC8634379.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    63. Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. Sci Rep. 2021 03 29; 11(1):7042. Tiwari S, Yang J, Morisseau C, Durbin-Johnson B, Hammock BD, Gomes AV. PMID: 33782432; PMCID: PMC8007717.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    64. Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain. ACS Omega. 2021 Mar 16; 6(10):7165-7174. Singh N, Barnych B, Wagner KM, Wan D, Morisseau C, Hammock BD. PMID: 33748630; PMCID: PMC7970556.
      View in: PubMed   Mentions: 11  
    65. Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and cardiovascular alterations in kidney transplant recipients. Sci Rep. 2021 02 12; 11(1):3739. Duflot T, Laurent C, Soudey A, Fonrose X, Hamzaoui M, Iacob M, Bertrand D, Favre J, Etienne I, Roche C, Coquerel D, Le Besnerais M, Louhichi S, Tarlet T, Li D, Brunel V, Morisseau C, Richard V, Joannidès R, Stanke-Labesque F, Lamoureux F, Guerrot D, Bellien J. PMID: 33580125; PMCID: PMC7881112.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    66. Adenosine A2A receptor and vascular response: role of soluble epoxide hydrolase, adenosine A1 receptor and angiotensin-II. Mol Cell Biochem. 2021 May; 476(5):1965-1978. Hanif A, Agba SO, Ledent C, Tilley SL, Morisseau C, Nayeem MA. PMID: 33511551.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    67. Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence. J Pain Res. 2021; 14:61-72. Wang Y, Wagner KM, Morisseau C, Hammock BD. PMID: 33488116; PMCID: PMC7814236.
      View in: PubMed   Mentions: 17  
    68. Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. J Med Chem. 2021 01 14; 64(1):184-215. Sun CP, Zhang XY, Morisseau C, Hwang SH, Zhang ZJ, Hammock BD, Ma XC. PMID: 33369424; PMCID: PMC7942193.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    69. N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain. J Nat Prod. 2020 12 24; 83(12):3689-3697. Singh N, Barnych B, Morisseau C, Wagner KM, Wan D, Takeshita A, Pham H, Xu T, Dandekar A, Liu JY, Hammock BD. PMID: 33320645; PMCID: PMC7888481.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    70. Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 2021; 11(3):815-830. Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG. PMID: 33068774; PMCID: PMC7851189.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    71. Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease. Neurotherapeutics. 2020 10; 17(4):1825-1835. Griñán-Ferré C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R, Sanfeliu C, Pérez B, Loza MI, Brea J, Morisseau C, Hammock BD, Vázquez S, Pallàs M, Galdeano C. PMID: 32488482; PMCID: PMC7851240.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    72. Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors. Front Pharmacol. 2020; 11:598858. Imig JD, Morisseau C. PMID: 33071800; PMCID: PMC7544929.
      View in: PubMed   Mentions: 5  
    73. Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity. Int J Mol Sci. 2020 Sep 24; 21(19). Overby H, Yang Y, Xu X, Graham K, Hildreth K, Choi S, Wan D, Morisseau C, Zeldin DC, Hammock BD, Wang S, Bettaieb A, Zhao L. PMID: 32987880; PMCID: PMC7582898.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    74. Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery. Nat Chem. 2020 10; 12(10):906-913. Brighty GJ, Botham RC, Li S, Nelson L, Mortenson DE, Li G, Morisseau C, Wang H, Hammock BD, Sharpless KB, Kelly JW. PMID: 32868886; PMCID: PMC7541551.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    75. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 11 15; 28(22):115735. Lee KSS, Ng JC, Yang J, Hwang SH, Morisseau C, Wagner K, Hammock BD. PMID: 33007552; PMCID: PMC7914304.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    76. Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies. Bioorg Chem. 2020 10; 103:104165. Wilt S, Kodani S, Le TNH, Nguyen L, Vo N, Ly T, Rodriguez M, Hudson PK, Morisseau C, Hammock BD, Pecic S. PMID: 32891856; PMCID: PMC7723751.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    77. Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci. 2020; 7:580. Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. PMID: 33005645; PMCID: PMC7479175.
      View in: PubMed   Mentions: 5  
    78. 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis. J Med Chem. 2020 09 10; 63(17):9237-9257. Codony S, Pujol E, Pizarro J, Feixas F, Valverde E, Loza MI, Brea JM, Saez E, Oyarzabal J, Pineda-Lucena A, Pérez B, Pérez C, Rodríguez-Franco MI, Leiva R, Osuna S, Morisseau C, Hammock BD, Vázquez-Carrera M, Vázquez S. PMID: 32787085; PMCID: PMC7755424.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    79. Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer. Anal Chem. 2020 09 01; 92(17):11654-11663. Li D, Cui Y, Morisseau C, Wagner KM, Cho YS, Hammock BD. PMID: 32786492; PMCID: PMC7745732.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    80. Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2020 09 15; 30(18):127430. Burmistrov V, Morisseau C, Karlov D, Pitushkin D, Vernigora A, Rasskazova E, Butov GM, Hammock BD. PMID: 32736212; PMCID: PMC7494652.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    81. The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification. Int J Mol Sci. 2020 Jun 17; 21(12). Varennes O, Mentaverri R, Duflot T, Kauffenstein G, Objois T, Lenglet G, Avondo C, Morisseau C, Brazier M, Kamel S, Six I, Bellien J. PMID: 32560362; PMCID: PMC7352784.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    82. Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model. FASEB J. 2020 07; 34(7):9074-9086. Trindade-da-Silva CA, Clemente-Napimoga JT, Abdalla HB, Rosa SM, Ueira-Vieira C, Morisseau C, Verri WA, Montalli VAM, Hammock BD, Napimoga MH. PMID: 32400048; PMCID: PMC7383812.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    83. Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients. Anal Chem. 2020 05 19; 92(10):7334-7342. Li D, Morisseau C, McReynolds CB, Duflot T, Bellien J, Nagra RM, Taha AY, Hammock BD. PMID: 32253910; PMCID: PMC7744119.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    84. Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 01; 193:112206. Barnych B, Singh N, Negrel S, Zhang Y, Magis D, Roux C, Hua X, Ding Z, Morisseau C, Tantillo DJ, Siegel JB, Hammock BD. PMID: 32203787; PMCID: PMC7366823.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    85. Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials and molecular dynamics. Bioorg Chem. 2020 03; 96:103637. Sun CP, Zhang J, Zhao WY, Yi J, Yan JK, Wang YL, Morisseau C, Liu ZB, Hammock BD, Ma XC. PMID: 32032849; PMCID: PMC7233170.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    86. Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation. Adv Exp Med Biol. 2020; 1274:71-99. McReynolds C, Morisseau C, Wagner K, Hammock B. PMID: 32894508; PMCID: PMC7737916.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    87. Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility. Bioorg Med Chem Lett. 2020 02 01; 30(3):126908. Burmistrov V, Morisseau C, D'yachenko V, Karlov D, Butov GM, Hammock BD. PMID: 31870649; PMCID: PMC6957307.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    88. Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain. J Med Chem. 2019 09 26; 62(18):8443-8460. Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. PMID: 31436984; PMCID: PMC7262789.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    89. Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Cent Sci. 2019 Sep 25; 5(9):1614-1624. Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. PMID: 31572788; PMCID: PMC6764161.
      View in: PubMed   Mentions: 18  
    90. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. Bioorg Med Chem. 2019 10 15; 27(20):115078. Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S. PMID: 31488357; PMCID: PMC6892585.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    91. 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. ACS Chem Neurosci. 2019 09 18; 10(9):4018-4030. Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. PMID: 31378059; PMCID: PMC7028313.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    92. Impact of the acute local inhibition of soluble epoxide hydrolase on diabetic skin microcirculatory dysfunction. Diab Vasc Dis Res. 2019 11; 16(6):523-529. Savina Y, Duflot T, Bounoure F, Kotzki S, Thiebaut PA, Serreau PA, Skiba M, Picquenot JM, Cornic M, Morisseau C, Hammock B, Imbert L, Cracowski JL, Richard V, Roustit M, Bellien J. PMID: 31267765; PMCID: PMC7307659.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    93. Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis. Front Pharmacol. 2019; 10:533. McReynolds CB, Hwang SH, Yang J, Wan D, Wagner K, Morisseau C, Li D, Schmidt WK, Hammock BD. PMID: 31214021; PMCID: PMC6554663.
      View in: PubMed   Mentions: 20  
    94. Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Front Pharmacol. 2019; 10:580. Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. PMID: 31191316; PMCID: PMC6548860.
      View in: PubMed   Mentions: 2  
    95. Computer-Aided Selective Optimization of Side Activities of Talinolol. ACS Med Chem Lett. 2019 Jun 13; 10(6):899-903. Hiesinger K, Kramer JS, Achenbach J, Moser D, Weber J, Wittmann SK, Morisseau C, Angioni C, Geisslinger G, Kahnt AS, Kaiser A, Proschak A, Steinhilber D, Pogoryelov D, Wagner K, Hammock BD, Proschak E. PMID: 31223445; PMCID: PMC6580380.
      View in: PubMed   Mentions: 3  
    96. N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase. Biochem Biophys Res Commun. 2019 07 12; 515(1):248-253. Matsumoto N, Kataoka M, Hirosaki H, Morisseau C, Hammock BD, Suzuki E, Hasumi K. PMID: 31146915; PMCID: PMC7395850.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    97. In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Front Pharmacol. 2019; 10:464. Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. PMID: 31143115; PMCID: PMC6520522.
      View in: PubMed   Mentions: 14  
    98. Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations. Int J Biol Macromol. 2019 Jul 15; 133:1187-1193. Liu ZB, Sun CP, Xu JX, Morisseau C, Hammock BD, Qiu F. PMID: 30980876.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    99. Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients. Cardiovasc Diabetol. 2019 03 18; 18(1):35. Duflot T, Moreau-Grangé L, Roche C, Iacob M, Wils J, Rémy-Jouet I, Cailleux AF, Leuillier M, Renet S, Li D, Morisseau C, Lamoureux F, Richard V, Prévost G, Joannidès R, Bellien J. PMID: 30885203; PMCID: PMC6423843.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    100. Fluoroaromatic fragments on 1,3-disubstituted ureas enhance soluble epoxide hydrolase inhibition. J Fluor Chem. 2019 Apr; 220:48-53. Burmistrov V, Morisseau C, D'yachenko V, Rybakov VB, Butov GM, Hammock BD. PMID: 32132741; PMCID: PMC7055688.
      View in: PubMed   Mentions: 2  
    101. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. Int J Biol Macromol. 2019 May 15; 129:653-658. de Oliveira GS, Adriani PP, Ribeiro JA, Morisseau C, Hammock BD, Dias MVB, Chambergo FS. PMID: 30771398; PMCID: PMC6447457.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    102. Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation. Biochimie. 2019 Apr; 159:59-65. Kodani SD, Morisseau C. PMID: 30716359; PMCID: PMC6431267.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    103. Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Anal Chim Acta. 2019 May 30; 1057:106-113. Vasylieva N, Kitamura S, Dong J, Barnych B, Hvorecny KL, Madden DR, Gee SJ, Wolan DW, Morisseau C, Hammock BD. PMID: 30832908; PMCID: PMC6426448.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    104. Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei. Mol Biol Rep. 2019 Feb; 46(1):371-379. de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS. PMID: 30426381; PMCID: PMC6426676.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    105. Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. ACS Omega. 2018 Oct 31; 3(10):14076-14086. Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. PMID: 30411058; PMCID: PMC6210075.
      View in: PubMed   Mentions: 14  
    106. Endocervical and Neutrophil Lipoxygenases Coordinate Neutrophil Transepithelial Migration to Neisseria gonorrhoeae. J Infect Dis. 2018 10 05; 218(10):1663-1674. Stevens JS, Gray MC, Morisseau C, Criss AK. PMID: 29905822; PMCID: PMC6173577.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    107. Adamantyl thioureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2018 07 15; 28(13):2302-2313. Burmistrov V, Morisseau C, Pitushkin D, Karlov D, Fayzullin RR, Butov GM, Hammock BD. PMID: 29803731; PMCID: PMC6442743.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    108. Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J Med Chem. 2018 05 10; 61(9):4271. Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 29701466; PMCID: PMC5949719.
      View in: PubMed   Mentions:    Fields:    
    109. Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem. 2018 04 26; 61(8):3541-3550. Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. PMID: 29614224; PMCID: PMC5933862.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    110. Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther. 2018 06; 365(3):467-475. Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S. PMID: 29567865; PMCID: PMC5931432.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    111. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat. 2018 05; 136:90-95. Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. PMID: 29567338; PMCID: PMC5970965.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    112. Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function. J Lipid Res. 2018 04; 59(4):684-695. Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR. PMID: 29459481; PMCID: PMC5880498.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    113. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett. 2018 02 15; 28(4):762-768. Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. PMID: 29366648; PMCID: PMC5837813.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    114. LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide. Methods Mol Biol. 2018; 1730:123-133. Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C. PMID: 29363071; PMCID: PMC5831730.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    115. Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability. Bioorg Chem. 2018 02; 76:510-527. Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD. PMID: 29310082; PMCID: PMC5837815.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    116. Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12608-12613. Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY. PMID: 29109264; PMCID: PMC5703276.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    117. Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts. Anal Biochem. 2017 12 15; 539:81-89. Kodani SD, Barthélemy M, Kamita SG, Hammock B, Morisseau C. PMID: 29054529; PMCID: PMC5696082.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    118. Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins. Prostaglandins Other Lipid Mediat. 2017 07; 131:83-95. Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Ledent C, Tilley SL, Nayeem MA. PMID: 28890385; PMCID: PMC5635996.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    119. Personalized polyunsaturated fatty acids as a potential adjunctive treatment for anorexia nervosa. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:11-19. Shih PB, Morisseau C, Le T, Woodside B, German JB. PMID: 28873340; PMCID: PMC5792652.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    120. Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. J Med Chem. 2017 07 13; 60(13):5392-5406. Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRR, Rana S, Contreras JI, Sahoo R, Wan D, Young J, Dias Teixeira KL, Morisseau C, Halperin J, Hammock B, Natarajan A, Wang P, Chorev M, Aktas BH. PMID: 28590739; PMCID: PMC5567831.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    121. Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers. Life Sci. 2017 Jul 01; 180:114-122. Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD. PMID: 28522175; PMCID: PMC5659729.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    122. Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP? Anal Chem. 2017 06 06; 89(11):6248-6256. Li D, Cui Y, Morisseau C, Gee SJ, Bever CS, Liu X, Wu J, Hammock BD, Ying Y. PMID: 28460522; PMCID: PMC5611449.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    123. Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L252-L266. Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. PMID: 28473326; PMCID: PMC5582936.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    124. Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales. PLoS One. 2017; 12(5):e0176571. Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD. PMID: 28472063; PMCID: PMC5417501.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    125. In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. Drug Metab Dispos. 2017 07; 45(7):712-720. Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z. PMID: 28428366; PMCID: PMC5452678.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    126. Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids. Proc Natl Acad Sci U S A. 2017 04 25; 114(17):4370-4375. Rand AA, Barnych B, Morisseau C, Cajka T, Lee KSS, Panigrahy D, Hammock BD. PMID: 28396419; PMCID: PMC5410821.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    127. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure. 2017 05 02; 25(5):697-707.e4. Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR. PMID: 28392259; PMCID: PMC5524515.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    128. Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice. PLoS One. 2017; 12(3):e0174137. Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Nayeem MA. PMID: 28328948; PMCID: PMC5362206.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    129. Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behav Brain Res. 2017 05 30; 326:69-76. Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. PMID: 28259677; PMCID: PMC5409858.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    130. Vascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-Hydroxylases. PLoS One. 2017; 12(1):e0169584. Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Nayeem MA. PMID: 28056085; PMCID: PMC5215949.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    131. Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators. Proc Natl Acad Sci U S A. 2017 01 03; 114(1):136-141. Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM. PMID: 27980032; PMCID: PMC5224368.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    132. Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorg Med Chem Lett. 2017 02 01; 27(3):620-625. Hwang SH, Wagner K, Xu J, Yang J, Li X, Cao Z, Morisseau C, Lee KS, Hammock BD. PMID: 28025003; PMCID: PMC5584617.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    133. Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Arch Biochem Biophys. 2017 Jan 01; 613:1-11. Lee KS, Henriksen NM, Ng CJ, Yang J, Jia W, Morisseau C, Andaya A, Gilson MK, Hammock BD. PMID: 27983948; PMCID: PMC5172606.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    134. Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use. J Ethnopharmacol. 2016 Dec 24; 194:475-482. Liu JY, Morisseau C, Huang H, Hammock BD. PMID: 27702689; PMCID: PMC5584568.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    135. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16; 262:92-99. Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. PMID: 27659731; PMCID: PMC5096949.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    136. Effect of Soluble Epoxide Hydrolase on the Modulation of Coronary Reactive Hyperemia: Role of Oxylipins and PPARγ. PLoS One. 2016; 11(9):e0162147. Hanif A, Edin ML, Zeldin DC, Morisseau C, Nayeem MA. PMID: 27583776; PMCID: PMC5008628.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    137. Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARγ. Am J Physiol Regul Integr Comp Physiol. 2016 10 01; 311(4):R676-R688. Hanif A, Edin ML, Zeldin DC, Morisseau C, Nayeem MA. PMID: 27488890; PMCID: PMC5142160.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    138. Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. Insect Biochem Mol Biol. 2016 09; 76:62-69. Xu J, Morisseau C, Yang J, Lee KSS, Kamita SG, Hammock BD. PMID: 27369469; PMCID: PMC5010450.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    139. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats. Toxicol Sci. 2016 08; 152(2):309-22. Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. PMID: 27208083; PMCID: PMC4960907.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    140. Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorg Med Chem. 2016 10 15; 24(20):4801-4811. Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. PMID: 27320659; PMCID: PMC5053890.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    141. Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa. J Med Chem. 2016 05 26; 59(10):4790-9. Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C. PMID: 27120257; PMCID: PMC4957648.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    142. Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther. 2016 06; 357(3):529-36. Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. PMID: 26989141; PMCID: PMC4885505.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    143. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):E1944-52. Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. PMID: 26976569; PMCID: PMC4822604.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    144. Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif. Biochemistry. 2016 Feb 09; 55(5):788-97. Bahl CD, Hvorecny KL, Morisseau C, Gerber SA, Madden DR. PMID: 26752215; PMCID: PMC4765904.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    145. Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. J Ocul Biol. 2016 Jan; 4(1). McLellan GJ, Aktas Z, Hennes-Beean E, Kolb AW, Larsen IV, Schmitz EJ, Clausius HR, Yang J, Hwang SH, Morisseau C, Inceoglu B, Hammock BD, Brandt CR. PMID: 28066796; PMCID: PMC5218821.
      View in: PubMed   Mentions: 3  
    146. Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays. Anal Chem. 2015 Dec 01; 87(23):11907-14. Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever CS, Lee KS, Morisseau C, Leizagoyen C, Gee S, Hammock BD, González-Sapienza G. PMID: 26544909; PMCID: PMC4666776.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    147. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model. Toxicol Appl Pharmacol. 2015 Dec 15; 289(3):419-27. Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. PMID: 26522832; PMCID: PMC4666679.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    148. 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2015 Dec 01; 25(23):5514-9. Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. PMID: 26520661; PMCID: PMC4654407.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    149. In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochem Pharmacol. 2015 Dec 15; 98(4):718-31. Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. PMID: 26494425; PMCID: PMC4656071.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    150. Aerobic exercise-based rehabilitation affects the activities of progenitor endothelial cells through EETs pathway. Med Hypotheses. 2015 Dec; 85(6):1037-8. Deng LM, Li XP, Xu DY, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 26454561; PMCID: PMC5003087.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    151. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem. 2015 Sep; 407(24):7275-83. Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD. PMID: 26229025; PMCID: PMC4573264.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    152. Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew Chem Int Ed Engl. 2015 Aug 17; 54(34):9881-5. Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. PMID: 26136396; PMCID: PMC4556431.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    153. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat. 2015 Sep; 121(Pt A):131-7. Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. PMID: 26117215; PMCID: PMC4688279.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    154. Impact of soluble epoxide hydrolase inhibition on early kidney damage in hyperglycemic overweight mice. Prostaglandins Other Lipid Mediat. 2015 Jul; 120:148-54. Roche C, Guerrot D, Harouki N, Duflot T, Besnier M, Rémy-Jouet I, Renet S, Dumesnil A, Lejeune A, Morisseau C, Richard V, Bellien J. PMID: 26022136; PMCID: PMC4575616.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    155. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacol Res. 2015 Jul; 97:7-15. Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. PMID: 25882247; PMCID: PMC4464910.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    156. High salt diet modulates vascular response in A2AAR (+/+) and A 2AAR (-/-) mice: role of sEH, PPARγ, and K ATP channels. Mol Cell Biochem. 2015 Jun; 404(1-2):87-96. Pradhan I, Ledent C, Mustafa SJ, Morisseau C, Nayeem MA. PMID: 25739357; PMCID: PMC4470368.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    157. Soluble epoxide hydrolase inhibition improves coronary endothelial function and prevents the development of cardiac alterations in obese insulin-resistant mice. Am J Physiol Heart Circ Physiol. 2015 May 01; 308(9):H1020-9. Roche C, Besnier M, Cassel R, Harouki N, Coquerel D, Guerrot D, Nicol L, Loizon E, Remy-Jouet I, Morisseau C, Mulder P, Ouvrard-Pascaud A, Madec AM, Richard V, Bellien J. PMID: 25724490; PMCID: PMC4551118.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    158. A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase. Chembiochem. 2015 Mar 23; 16(5):766-71. Nollmann FI, Heinrich AK, Brachmann AO, Morisseau C, Mukherjee K, Casanova-Torres ÁM, Strobl F, Kleinhans D, Kinski S, Schultz K, Beeton ML, Kaiser M, Chu YY, Phan Ke L, Thanwisai A, Bozhüyük KA, Chantratita N, Götz F, Waterfield NR, Vilcinskas A, Stelzer EH, Goodrich-Blair H, Hammock BD, Bode HB. PMID: 25711603; PMCID: PMC4486325.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    159. Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis. Atherosclerosis. 2015 Apr; 239(2):557-65. Shen L, Peng H, Peng R, Fan Q, Zhao S, Xu D, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 25733327; PMCID: PMC4527317.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    160. Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. Insect Biochem Mol Biol. 2015 Apr; 59:41-9. Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD. PMID: 25686802; PMCID: PMC4387068.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    161. Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo. PLoS One. 2015; 10(2):e0117438. Kitamura S, Morisseau C, Inceoglu B, Kamita SG, De Nicola GR, Nyegue M, Hammock BD. PMID: 25659109; PMCID: PMC4319826.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    162. Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration. J Immunol. 2015 Feb 01; 194(3):1304-15. Pazos MA, Pirzai W, Yonker LM, Morisseau C, Gronert K, Hurley BP. PMID: 25548217; PMCID: PMC4297725.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    163. Soluble epoxide hydrolase deficiency ameliorates acute pancreatitis in mice. Free Radic Biol Med. 2014 Oct; 75 Suppl 1:S32. Bettaieb A, Morisseau C, Hammock B, Haj F. PMID: 26461340.
      View in: PubMed   Mentions: 1     Fields:    
    164. Identification of potent inhibitors of the chicken soluble epoxide hydrolase. Bioorg Med Chem Lett. 2015 Jan 15; 25(2):276-9. Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. PMID: 25479771; PMCID: PMC4277729.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    165. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemother Pharmacol. 2015 Jan; 75(1):161-71. Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. PMID: 25413440; PMCID: PMC4400119.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    166. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. PLoS One. 2014; 9(11):e113019. Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. PMID: 25402489; PMCID: PMC4234494.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    167. Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model. J Vasc Res. 2014; 51(4):269-82. Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK. PMID: 25196102; PMCID: PMC4235611.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    168. Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids. Insect Biochem Mol Biol. 2014 Nov; 54:42-52. Xu J, Morisseau C, Hammock BD. PMID: 25173592; PMCID: PMC4252830.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    169. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 2014 Aug 28; 57(16):7016-30. Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. PMID: 25079952; PMCID: PMC4148150.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    170. Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core. Eur J Med Chem. 2014 Sep 12; 84:160-72. Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. PMID: 25016374.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    171. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8167-72. Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. PMID: 24843165; PMCID: PMC4050620.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    172. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. J Lipid Res. 2014 06; 55(6):1131-8. Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. PMID: 24771868; PMCID: PMC4031944.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    173. Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2014 May 01; 24(9):2193-7. Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD. PMID: 24685540; PMCID: PMC4019751.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    174. Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors. Eur J Med Chem. 2014 Apr 22; 77:343-50. Kálai T, Altman R, Maezawa I, Balog M, Morisseau C, Petrlova J, Hammock BD, Jin LW, Trudell JR, Voss JC, Hideg K. PMID: 24657571; PMCID: PMC4065883.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    175. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One. 2013; 8(12):e80922. Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. PMID: 24349022; PMCID: PMC3862847.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    176. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. J Med Chem. 2013 Dec 12; 56(23):9457-70. Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH. PMID: 24261904; PMCID: PMC3938169.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    177. Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2013 Sep; 62(3):285-97. Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. PMID: 23676336; PMCID: PMC3773051.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    178. Characterization of Hovi-mEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis. Arch Insect Biochem Physiol. 2013 Aug; 83(4):171-9. Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety RS, Falk BW. PMID: 23704009; PMCID: PMC3846607.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    179. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3732-7. Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. PMID: 23726028; PMCID: PMC3744640.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    180. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett. 2013 Jul 01; 23(13):3818-21. Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. PMID: 23684894; PMCID: PMC3703951.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    181. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem. 2013 May 17; 288(20):14189-14199. Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. PMID: 23576437; PMCID: PMC3656275.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    182. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg. 2013 Jul; 40(4):440-8. Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. PMID: 23463912; PMCID: PMC3956586.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    183. Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties. Bioorg Med Chem. 2013 May 01; 21(9):2587-99. North EJ, Scherman MS, Bruhn DF, Scarborough JS, Maddox MM, Jones V, Grzegorzewicz A, Yang L, Hess T, Morisseau C, Jackson M, McNeil MR, Lee RE. PMID: 23498915; PMCID: PMC3780361.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    184. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013 Mar 12; 48(4-5):619-27. Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. PMID: 23291046; PMCID: PMC3596469.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    185. Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties. Nat Commun. 2013; 4:1840. de Medina P, Paillasse MR, Segala G, Voisin M, Mhamdi L, Dalenc F, Lacroix-Triki M, Filleron T, Pont F, Saati TA, Morisseau C, Hammock BD, Silvente-Poirot S, Poirot M. PMID: 23673625; PMCID: PMC3674249.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    186. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. Eur J Pharmacol. 2013 Jan 30; 700(1-3):93-101. Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. PMID: 23276668; PMCID: PMC3578047.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    187. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochem Mol Biol. 2013 Mar; 43(3):219-28. Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. PMID: 23276675; PMCID: PMC3577957.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    188. Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model. Prostaglandins Other Lipid Mediat. 2013 Jul-Aug; 104-105:42-8. Chen L, Fan C, Zhang Y, Bakri M, Dong H, Morisseau C, Maddipati KR, Luo P, Wang CY, Hammock BD, Wang MH. PMID: 23247129; PMCID: PMC4052893.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    189. Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Anal Biochem. 2013 Mar 15; 434(2):259-68. Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. PMID: 23219719; PMCID: PMC3632402.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    190. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Anal Biochem. 2013 Mar 01; 434(1):105-11. Morisseau C, Sahdeo S, Cortopassi G, Hammock BD. PMID: 23219563; PMCID: PMC3557602.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    191. Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2013 Jan 15; 23(2):417-21. Pecic S, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD, Zhu Z, Rinderspacher A, Deng SX. PMID: 23237835; PMCID: PMC3541548.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    192. Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 01; 304(1):R23-32. Nayeem MA, Pradhan I, Mustafa SJ, Morisseau C, Falck JR, Zeldin DC. PMID: 23152114; PMCID: PMC3543649.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    193. Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures. Chromatographia. 2013 Jan 01; 76(1-2):13-21. Falck D, Schebb NH, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM. PMID: 23526703; PMCID: PMC3601784.
      View in: PubMed   Mentions:
    194. Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. J Immunol. 2012 Nov 15; 189(10):4960-9. Tamang DL, Pirzai W, Priebe GP, Traficante DC, Pier GB, Falck JR, Morisseau C, Hammock BD, McCormick BA, Gronert K, Hurley BP. PMID: 23045615; PMCID: PMC3490410.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    195. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol. 2013; 53:37-58. Morisseau C, Hammock BD. PMID: 23020295; PMCID: PMC3578707.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansAnimals
    196. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett. 2012 Sep 15; 22(18):5889-92. Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. PMID: 22901393; PMCID: PMC3432147.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    197. EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. J Lipid Res. 2012 Oct; 53(10):2038-2045. Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC, Arand M. PMID: 22798687; PMCID: PMC3435537.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    198. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11390-5. Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. PMID: 22733772; PMCID: PMC3396532.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    199. Role of epoxide hydrolases in lipid metabolism. Biochimie. 2013 Jan; 95(1):91-5. Morisseau C. PMID: 22722082; PMCID: PMC3495083.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    200. Soluble epoxide hydrolase expression in a porcine model of arteriovenous graft stenosis and anti-inflammatory effects of a soluble epoxide hydrolase inhibitor. Am J Physiol Cell Physiol. 2012 Aug 01; 303(3):C278-90. Sanders WG, Morisseau C, Hammock BD, Cheung AK, Terry CM. PMID: 22621785; PMCID: PMC3423029.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    201. A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction. Int J Cardiol. 2013 Aug 20; 167(4):1298-304. Xu DY, Davis BB, Wang ZH, Zhao SP, Wasti B, Liu ZL, Li N, Morisseau C, Chiamvimonvat N, Hammock BD. PMID: 22525341; PMCID: PMC3821736.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    202. Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability. Bioorg Med Chem. 2012 May 15; 20(10):3255-62. Scherman MS, North EJ, Jones V, Hess TN, Grzegorzewicz AE, Kasagami T, Kim IH, Merzlikin O, Lenaerts AJ, Lee RE, Jackson M, Morisseau C, McNeil MR. PMID: 22522007; PMCID: PMC3345085.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    203. Structure-based optimization of the piperazino-containing 1,3-disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase. Medchemcomm. 2012 Mar 01; (3):379-384. Huang SX, Cao B, Morisseau C, Jin Y, Hammock BD, Long YQ. PMID: 25225606; PMCID: PMC4163146.
      View in: PubMed   Mentions: 7  
    204. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochem Biophys Res Commun. 2012 Mar 23; 419(4):796-800. Morisseau C, Schebb NH, Dong H, Ulu A, Aronov PA, Hammock BD. PMID: 22387545; PMCID: PMC3313618.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    205. Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane. Nat Chem Biol. 2012 Feb 19; 8(4):334-41. Grzegorzewicz AE, Pham H, Gundi VA, Scherman MS, North EJ, Hess T, Jones V, Gruppo V, Born SE, Korduláková J, Chavadi SS, Morisseau C, Lenaerts AJ, Lee RE, McNeil MR, Jackson M. PMID: 22344175; PMCID: PMC3307863.
      View in: PubMed   Mentions: 209     Fields:    Translation:Cells
    206. Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules. Toxicol Appl Pharmacol. 2012 Apr 01; 260(1):17-26. Duan H, Yoshimura K, Kobayashi N, Sugiyama K, Sawada J, Saito Y, Morisseau C, Hammock BD, Akatsuka T. PMID: 22310175; PMCID: PMC3319115.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    207. Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase. Toxicol Appl Pharmacol. 2012 Apr 01; 260(1):27-34. Duan H, Takagi A, Kayano H, Koyama I, Morisseau C, Hammock BD, Akatsuka T. PMID: 22306621; PMCID: PMC3319120.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    208. Corncob bedding alters the effects of estrogens on aggressive behavior and reduces estrogen receptor-α expression in the brain. Endocrinology. 2012 Feb; 153(2):949-53. Villalon Landeros R, Morisseau C, Yoo HJ, Fu SH, Hammock BD, Trainor BC. PMID: 22186416; PMCID: PMC3275391.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    209. N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase. Cardiovasc Res. 2012 Jan 01; 93(1):120-9. Hou HH, Hammock BD, Su KH, Morisseau C, Kou YR, Imaoka S, Oguro A, Shyue SK, Zhao JF, Lee TS. PMID: 22072631; PMCID: PMC3243038.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    210. Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett. 2012 Jan 01; 22(1):601-5. Pecic S, Deng SX, Morisseau C, Hammock BD, Landry DW. PMID: 22079754; PMCID: PMC3337727.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    211. Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats. Exp Diabetes Res. 2012; 2012:758614. Iyer A, Kauter K, Alam MA, Hwang SH, Morisseau C, Hammock BD, Brown L. PMID: 22007192; PMCID: PMC3191770.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    212. The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem. 2011 Sep 15; 19(18):5585-95. Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Korduláková J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. PMID: 21840723; PMCID: PMC3176295.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    213. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicol Appl Pharmacol. 2011 Sep 01; 255(2):200-6. Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. PMID: 21741984; PMCID: PMC3156297.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    214. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal Bioanal Chem. 2011 May; 400(5):1359-66. Schebb NH, Huby M, Morisseau C, Hwang SH, Hammock BD. PMID: 21479549; PMCID: PMC3081056.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    215. Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. J Med Chem. 2011 Apr 28; 54(8):3037-50. Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. PMID: 21434686; PMCID: PMC3281519.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    216. Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line. Toxicol Appl Pharmacol. 2011 May 15; 253(1):45-56. Barhoumi R, Mouneimne Y, Ramos E, Morisseau C, Hammock BD, Safe S, Parrish AR, Burghardt RC. PMID: 21420996; PMCID: PMC3081912.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    217. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):5093-7. Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. PMID: 21383170; PMCID: PMC3064364.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    218. Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects. Environ Sci Technol. 2011 Apr 01; 45(7):3109-15. Schebb NH, Inceoglu B, Ahn KC, Morisseau C, Gee SJ, Hammock BD. PMID: 21381656; PMCID: PMC3470465.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsPHPublic Health
    219. Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies. Anal Biochem. 2011 Jul 01; 414(1):154-62. Morisseau C, Bernay M, Escaich A, Sanborn JR, Lango J, Hammock BD. PMID: 21371418; PMCID: PMC3090455.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    220. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. Am J Physiol Endocrinol Metab. 2011 Apr; 300(4):E691-8. Koeners MP, Wesseling S, Ulu A, Sepúlveda RL, Morisseau C, Braam B, Hammock BD, Joles JA. PMID: 21266668; PMCID: PMC3074945.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    221. Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation. Circ Res. 2011 Feb 04; 108(3):324-34. Charles RL, Burgoyne JR, Mayr M, Weldon SM, Hubner N, Dong H, Morisseau C, Hammock BD, Landar A, Eaton P. PMID: 21164107; PMCID: PMC3259859.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    222. Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties. J Med Chem. 2010 Dec 09; 53(23):8376-86. Huang SX, Li HY, Liu JY, Morisseau C, Hammock BD, Long YQ. PMID: 21070033; PMCID: PMC3070159.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    223. 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain. J Med Chem. 2010 Oct 14; 53(19):7067-75. Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. PMID: 20812725; PMCID: PMC3285450.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimals
    224. Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease. PLoS One. 2010 Aug 04; 5(8):e11979. Jung O, Jansen F, Mieth A, Barbosa-Sicard E, Pliquett RU, Babelova A, Morisseau C, Hwang SH, Tsai C, Hammock BD, Schaefer L, Geisslinger G, Amann K, Brandes RP. PMID: 20694143; PMCID: PMC2915917.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    225. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res. 2010 Dec; 51(12):3481-90. Morisseau C, Inceoglu B, Schmelzer K, Tsai HJ, Jinks SL, Hegedus CM, Hammock BD. PMID: 20664072; PMCID: PMC2975720.
      View in: PubMed   Mentions: 139     Fields:    Translation:Animals
    226. Function of phenylalanine 259 and threonine 314 within the substrate binding pocket of the juvenile hormone esterase of Manduca sexta. Biochemistry. 2010 May 04; 49(17):3733-42. Kamita SG, Wogulis MD, Law CS, Morisseau C, Tanaka H, Huang H, Wilson DK, Hammock BD. PMID: 20307057; PMCID: PMC3570046.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    227. Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. J Pharmacol Exp Ther. 2010 Aug; 334(2):430-8. Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH. PMID: 20439437; PMCID: PMC2913776.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    228. Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase. Am J Physiol Regul Integr Comp Physiol. 2010 Jul; 299(1):R325-33. Nayeem MA, Zeldin DC, Boegehold MA, Morisseau C, Marowsky A, Ponnoth DS, Roush KP, Falck JR. PMID: 20427718; PMCID: PMC2904154.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    229. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. Eur J Pharm Sci. 2010 Jun 14; 40(3):222-38. Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD. PMID: 20359531; PMCID: PMC3285443.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    230. Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice. Arterioscler Thromb Vasc Biol. 2010 May; 30(5):909-14. Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. PMID: 20224052; PMCID: PMC2919323.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    231. Impact of epoxyeicosatrienoic acids in lung ischemia-reperfusion injury. Microcirculation. 2010 Feb; 17(2):137-46. Townsley MI, Morisseau C, Hammock B, King JA. PMID: 20163540; PMCID: PMC2923642.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    232. Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor. J Bacteriol. 2010 Apr; 192(7):1785-95. Bahl CD, Morisseau C, Bomberger JM, Stanton BA, Hammock BD, O'Toole GA, Madden DR. PMID: 20118260; PMCID: PMC2838060.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    233. Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase. Curr Pharm Biotechnol. 2009 Sep; 10(6):589-99. Matveeva EG, Morisseau C, Goodrow MH, Mullin C, Hammock BD. PMID: 19619123; PMCID: PMC2861369.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    234. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition. J Med Chem. 2009 Aug 27; 52(16):5069-75. Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi XY, Goldman DH, Morisseau C, Hammock BD, Campbell WB. PMID: 19653681; PMCID: PMC2888647.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    235. Inhibition of the soluble epoxide hydrolase by tyrosine nitration. J Biol Chem. 2009 Oct 09; 284(41):28156-28163. Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I. PMID: 19704161; PMCID: PMC2788866.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    236. Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. Mol Cancer Ther. 2009 Aug; 8(8):2193-203. Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH. PMID: 19671760; PMCID: PMC2728155.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    237. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect. 2009 Dec; 117(12):1867-72. Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. PMID: 20049205; PMCID: PMC2799460.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    238. Expression and regulation of soluble epoxide hydrolase in adipose tissue. Obesity (Silver Spring). 2010 Mar; 18(3):489-98. De Taeye BM, Morisseau C, Coyle J, Covington JW, Luria A, Yang J, Murphy SB, Friedman DB, Hammock BB, Vaughan DE. PMID: 19644452; PMCID: PMC2864128.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    239. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E375-83. Luria A, Morisseau C, Tsai HJ, Yang J, Inceoglu B, De Taeye B, Watkins SM, Wiest MM, German JB, Hammock BD. PMID: 19458064; PMCID: PMC2724109.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    240. Novel and highly sensitive fluorescent assay for leucine aminopeptidases. Anal Biochem. 2009 Aug 01; 391(1):11-6. Huang H, Tanaka H, Hammock BD, Morisseau C. PMID: 19433052; PMCID: PMC2748848.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    241. Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats. J Hypertens. 2009 Feb; 27(2):322-31. Revermann M, Barbosa-Sicard E, Dony E, Schermuly RT, Morisseau C, Geisslinger G, Fleming I, Hammock BD, Brandes RP. PMID: 19226702; PMCID: PMC2863009.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    242. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorg Med Chem Lett. 2009 Mar 15; 19(6):1784-9. Kasagami T, Kim IH, Tsai HJ, Nishi K, Hammock BD, Morisseau C. PMID: 19216074; PMCID: PMC2900318.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    243. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. Br J Pharmacol. 2009 Jan; 156(2):284-96. Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. PMID: 19154430; PMCID: PMC2697843.
      View in: PubMed   Mentions: 69     Fields:    Translation:Animals
    244. Differential subcellular distribution and colocalization of the microsomal and soluble epoxide hydrolases in cultured neonatal rat brain cortical astrocytes. J Neurosci Res. 2009 Jan; 87(1):218-27. Rawal S, Morisseau C, Hammock BD, Shivachar AC. PMID: 18711743; PMCID: PMC3592782.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    245. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18901-6. Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD. PMID: 19028872; PMCID: PMC2596245.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    246. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. J Cardiovasc Pharmacol. 2008 Oct; 52(4):314-23. Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. PMID: 18791465; PMCID: PMC2637359.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    247. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. J Pharmacol Exp Ther. 2008 Dec; 327(3):707-15. Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL. PMID: 18815352; PMCID: PMC2761654.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    248. Discovery of potent non-urea inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett. 2009 Apr 15; 19(8):2354-9. Xie Y, Liu Y, Gong G, Smith DH, Yan F, Rinderspacher A, Feng Y, Zhu Z, Li X, Deng SX, Branden L, Vidovic D, Chung C, Schürer S, Morisseau C, Hammock BD, Landry DW. PMID: 19303288; PMCID: PMC2738751.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    249. The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor. J Mol Biol. 2008 Sep 12; 381(4):897-912. Biswal BK, Morisseau C, Garen G, Cherney MM, Garen C, Niu C, Hammock BD, James MN. PMID: 18585390; PMCID: PMC2866126.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    250. Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical. Pest Manag Sci. 2008 Jun; 64(6):594-609. Morisseau C, Hammock BD. PMID: 18383502.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    251. Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells. J Pharmacol Exp Ther. 2008 Jul; 326(1):330-7. Jiang H, Zhu AG, Mamczur M, Morisseau C, Hammock BD, Falck JR, McGiff JC. PMID: 18445784; PMCID: PMC2732189.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    252. Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. Cell Biol Toxicol. 2009 Jun; 25(3):217-25. Parrish AR, Chen G, Burghardt RC, Watanabe T, Morisseau C, Hammock BD. PMID: 18386137; PMCID: PMC3033346.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    253. Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol. 2008 Apr; 21(4):951-7. Morisseau C, Newman JW, Wheelock CE, Hill Iii T, Morin D, Buckpitt AR, Hammock BD. PMID: 18363382.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    254. Transcriptional regulation of the human soluble epoxide hydrolase gene EPHX2. Biochim Biophys Acta. 2008 Jan; 1779(1):17-27. Tanaka H, Kamita SG, Wolf NM, Harris TR, Wu Z, Morisseau C, Hammock BD. PMID: 18078836; PMCID: PMC2699939.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    255. 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. J Med Chem. 2007 Oct 18; 50(21):5217-26. Kim IH, Tsai HJ, Nishi K, Kasagami T, Morisseau C, Hammock BD. PMID: 17894481; PMCID: PMC2543935.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    256. Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. Arterioscler Thromb Vasc Biol. 2007 Dec; 27(12):2612-8. Fleming I, Rueben A, Popp R, Fisslthaler B, Schrodt S, Sander A, Haendeler J, Falck JR, Morisseau C, Hammock BD, Busse R. PMID: 17872452.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    257. Orally bioavailable potent soluble epoxide hydrolase inhibitors. J Med Chem. 2007 Aug 09; 50(16):3825-40. Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. PMID: 17616115; PMCID: PMC2596069.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    258. Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F342-9. Huang H, Morisseau C, Wang J, Yang T, Falck JR, Hammock BD, Wang MH. PMID: 17442729.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    259. Soluble epoxide hydrolase: a novel therapeutic target in stroke. J Cereb Blood Flow Metab. 2007 Dec; 27(12):1931-40. Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. PMID: 17440491; PMCID: PMC2664093.
      View in: PubMed   Mentions: 123     Fields:    Translation:Animals
    260. Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A. J Autoimmun. 2007 Feb; 28(1):7-18. Akatsuka T, Kobayashi N, Ishikawa T, Saito T, Shindo M, Yamauchi M, Kurokohchi K, Miyazawa H, Duan H, Matsunaga T, Komoda T, Morisseau C, Hammock BD. PMID: 17296285; PMCID: PMC1892246.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    261. Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase. Cell Biochem Biophys. 2007; 47(1):87-98. Loch D, Hoey A, Morisseau C, Hammock BO, Brown L. PMID: 17406062; PMCID: PMC1892223.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    262. Measurement of soluble epoxide hydrolase (sEH) activity. Curr Protoc Toxicol. 2007; Chapter 4:Unit 4.23. Morisseau C, Hammock BD. PMID: 23045145.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    263. Effect of ionic liquids on epoxide hydrolase-catalyzed synthesis of chiral 1,2-diols. Green Chem. 2007; 2007(9):162-168. Chiappe C, Leandri E, Hammock BD, Morisseau C. PMID: 18160974; PMCID: PMC2153531.
      View in: PubMed   Mentions: 3  
    264. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. J Biol Chem. 2007 Feb 02; 282(5):2891-8. Luria A, Weldon SM, Kabcenell AK, Ingraham RH, Matera D, Jiang H, Gill R, Morisseau C, Newman JW, Hammock BD. PMID: 17135253; PMCID: PMC2040337.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimals
    265. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett. 2006 Oct 15; 16(20):5439-44. Morisseau C, Newman JW, Tsai HJ, Baecker PA, Hammock BD. PMID: 16908134; PMCID: PMC1892215.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    266. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorg Med Chem. 2007 Jan 01; 15(1):312-23. Kim IH, Nishi K, Tsai HJ, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield J, Toth I, Hammock BD. PMID: 17046265; PMCID: PMC2040326.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    267. Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 2006 Nov 15; 16(22):5773-7. Hwang SH, Morisseau C, Do Z, Hammock BD. PMID: 16949285; PMCID: PMC1904340.
      View in: PubMed   Mentions: 17     Fields:    
    268. Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1. Arterioscler Thromb Vasc Biol. 2006 Nov; 26(11):2462-8. Ng VY, Morisseau C, Falck JR, Hammock BD, Kroetz DL. PMID: 16917105; PMCID: PMC1904341.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    269. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett. 2006 Oct 01; 16(19):5212-6. Jones PD, Tsai HJ, Do ZN, Morisseau C, Hammock BD. PMID: 16870439; PMCID: PMC1904344.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    270. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins Other Lipid Mediat. 2007 Jan; 82(1-4):42-9. Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. PMID: 17164131; PMCID: PMC1904338.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    271. The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase. Bioorg Med Chem. 2006 Oct 01; 14(19):6586-92. Li HY, Jin Y, Morisseau C, Hammock BD, Long YQ. PMID: 16784862; PMCID: PMC2040075.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    272. Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. J Pharmacol Exp Ther. 2006 Sep; 318(3):1307-14. Olearczyk JJ, Field MB, Kim IH, Morisseau C, Hammock BD, Imig JD. PMID: 16772540.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    273. Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem. 2006 Aug 01; 355(1):71-80. Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD. PMID: 16729954; PMCID: PMC1964503.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    274. High-throughput pharmacokinetic method: cassette dosing in mice associated with minuscule serial bleedings and LC/MS/MS analysis. Anal Chim Acta. 2006 Feb 10; 559(1):37-44. Watanabe T, Schulz D, Morisseau C, Hammock BD. PMID: 16636700; PMCID: PMC1447531.
      View in: PubMed   Mentions: 26     Fields:    
    275. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Arch Biochem Biophys. 2006 Jan 01; 445(1):115-23. Nishi K, Huang H, Kamita SG, Kim IH, Morisseau C, Hammock BD. PMID: 16359636; PMCID: PMC1444892.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    276. Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids. Protein Sci. 2006 Jan; 15(1):58-64. Gomez GA, Morisseau C, Hammock BD, Christianson DW. PMID: 16322563; PMCID: PMC1762130.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    277. The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proc Natl Acad Sci U S A. 2005 Nov 15; 102(46):16747-52. Liu Y, Zhang Y, Schmelzer K, Lee TS, Fang X, Zhu Y, Spector AA, Gill S, Morisseau C, Hammock BD, Shyy JY. PMID: 16267130; PMCID: PMC1276614.
      View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
    278. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. J Pharmacol Exp Ther. 2006 Feb; 316(2):815-21. Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. PMID: 16221742.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    279. Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry. 2005 Sep 13; 44(36):12179-87. Tran KL, Aronov PA, Tanaka H, Newman JW, Hammock BD, Morisseau C. PMID: 16142916; PMCID: PMC1473036.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    280. Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies. Anal Biochem. 2005 Aug 01; 343(1):66-75. Jones PD, Wolf NM, Morisseau C, Whetstone P, Hock B, Hammock BD. PMID: 15963942; PMCID: PMC1447601.
      View in: PubMed   Mentions: 95     Fields:    
    281. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. J Med Chem. 2005 May 19; 48(10):3621-9. Kim IH, Heirtzler FR, Morisseau C, Nishi K, Tsai HJ, Hammock BD. PMID: 15887969; PMCID: PMC1450255.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    282. Epoxide hydrolases: their roles and interactions with lipid metabolism. Prog Lipid Res. 2005 Jan; 44(1):1-51. Newman JW, Morisseau C, Hammock BD. PMID: 15748653.
      View in: PubMed   Mentions: 191     Fields:    Translation:Animals
    283. Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB J. 2005 Apr; 19(6):626-8. Sellers KW, Sun C, Diez-Freire C, Waki H, Morisseau C, Falck JR, Hammock BD, Paton JF, Raizada MK. PMID: 15659536.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    284. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annu Rev Pharmacol Toxicol. 2005; 45:311-33. Morisseau C, Hammock BD. PMID: 15822179.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansAnimals
    285. Identification and characterization of an ovary-selective isoform of epoxide hydrolase. Biol Reprod. 2005 Apr; 72(4):968-75. Hennebold JD, Mah K, Perez W, Vance JE, Stouffer RL, Morisseau C, Hammock BD, Adashi EY. PMID: 15601917.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    286. Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis. Arch Biochem Biophys. 2004 Oct 15; 430(2):247-55. Stok JE, Goloshchapov A, Song C, Wheelock CE, Derbel MB, Morisseau C, Hammock BD. PMID: 15369824.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    287. Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes. J Biol Chem. 2004 Jul 09; 279(28):29863-9. Stok JE, Huang H, Jones PD, Wheelock CE, Morisseau C, Hammock BD. PMID: 15123619.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    288. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 2004 Apr 27; 43(16):4716-23. Gomez GA, Morisseau C, Hammock BD, Christianson DW. PMID: 15096040.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    289. Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. J Med Chem. 2004 Apr 08; 47(8):2110-22. Kim IH, Morisseau C, Watanabe T, Hammock BD. PMID: 15056008.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    290. Isolation of a strain of Agrobacterium tumefaciens (Rhizobium radiobacter) utilizing methylene urea (ureaformaldehyde) as nitrogen source. Can J Microbiol. 2004 Mar; 50(3):167-74. Koivunen ME, Morisseau C, Horwath WR, Hammock BD. PMID: 15105883.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    291. Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicol Sci. 2004 Apr; 78(2):187-95. DuTeaux SB, Newman JW, Morisseau C, Fairbairn EA, Jelks K, Hammock BD, Miller MG. PMID: 14737000.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    292. Vascular localization of soluble epoxide hydrolase in the human kidney. Am J Physiol Renal Physiol. 2004 Apr; 286(4):F720-6. Yu Z, Davis BB, Morisseau C, Hammock BD, Olson JL, Kroetz DL, Weiss RH. PMID: 14665429.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    293. In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea. Drug Metab Dispos. 2003 Jul; 31(7):846-53. Watanabe T, Morisseau C, Newman JW, Hammock BD. PMID: 12814960.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    294. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes. Anal Biochem. 2003 Apr 15; 315(2):208-22. Wheelock CE, Wheelock AM, Zhang R, Stok JE, Morisseau C, Le Valley SE, Green CE, Hammock BD. PMID: 12689831.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    295. QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds. J Med Chem. 2003 Mar 13; 46(6):1066-80. McElroy NR, Jurs PC, Morisseau C, Hammock BD. PMID: 12620084.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    296. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1558-63. Newman JW, Morisseau C, Harris TR, Hammock BD. PMID: 12574510; PMCID: PMC149871.
      View in: PubMed   Mentions: 102     Fields:    Translation:Humans
    297. Urea and amide-based inhibitors of the juvenile hormone epoxide hydrolase of the tobacco hornworm (Manduca sexta: Sphingidae). Insect Biochem Mol Biol. 2002 Dec; 32(12):1741-56. Severson TF, Goodrow MH, Morisseau C, Dowdy DL, Hammock BD. PMID: 12429126.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    298. Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Hypertension. 2002 Oct; 40(4):485-90. Fornage M, Hinojos CA, Nurowska BW, Boerwinkle E, Hammock BD, Morisseau CH, Doris PA. PMID: 12364351.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    299. Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2306-14. Fang X, Weintraub NL, Oltman CL, Stoll LL, Kaduce TL, Harmon S, Dellsperger KC, Morisseau C, Hammock BD, Spector AA. PMID: 12388281.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    300. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol. 2002 May 01; 63(9):1599-608. Morisseau C, Goodrow MH, Newman JW, Wheelock CE, Dowdy DL, Hammock BD. PMID: 12007563.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    301. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2222-7. Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD, Weiss RH. PMID: 11842228; PMCID: PMC122346.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    302. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension. 2002 Feb; 39(2 Pt 2):690-4. Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD. PMID: 11882632.
      View in: PubMed   Mentions: 177     Fields:    Translation:Animals
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