Isaac Pessah

Title(s)Professor, School of Veterinary Medicine
SchoolSchool of Veterinary Medicine
Address2203 VM3B
CA 95616
Phone530-752-6696
ORCID ORCID Icon0000-0002-8149-588X Additional info
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    Collapse Biography 
    Collapse Education and Training
    Cornell University, Ithaca, NYB.S.06-1977Biological Sciences
    University of Maryland, College Park, MDPh.D.12-1983Toxicology
    Collapse Awards and Honors
    AAAS2018Elected AAAS Fellow

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell. Nat Commun. 2024 Jan 16; 15(1):526. Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz RL, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. PMID: 38228630; PMCID: PMC10791687.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. Ex vivo exposure to polybrominated diphenyl ether (PBDE) selectively affects the immune response in autistic children. Brain Behav Immun Health. 2023 Dec; 34:100697. Akintunde ME, Lin YP, Krakowiak P, Pessah IN, Hertz-Picciotto I, Puschner B, Ashwood P, Van de Water J. PMID: 38020477; PMCID: PMC10654005.
      View in: PubMed   Mentions:
    3. The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear. Res Sq. 2023 Jul 12. Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz R, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. PMID: 37502846; PMCID: PMC10371147.
      View in: PubMed   Mentions: 1  
    4. Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance. J Biol Chem. 2023 08; 299(8):104992. Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN. PMID: 37392848; PMCID: PMC10413282.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Investigations into hydrogen sulfide-induced suppression of neuronal activity in vivo and calcium dysregulation in vitro. Toxicol Sci. 2023 Mar 06. Kim DS, Pessah IN, Santana CM, Purnell B, Li R, Buchanan GF, Rumbeiha WK. PMID: 36882182; PMCID: PMC10109532.
      View in: PubMed   Mentions: 4     Fields:    
    6. Ryanodine receptor-active non-dioxin-like polychlorinated biphenyls cause neurobehavioral deficits in larval zebrafish. Front Toxicol. 2022; 4:947795. Yaghoobi B, Miller GW, Holland EB, Li X, Harvey D, Li S, Lehmler HJ, Pessah IN, Lein PJ. PMID: 36278027; PMCID: PMC9582434.
      View in: PubMed   Mentions: 5  
    7. Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. Nat Genet. 2022 09; 54(9):1320-1331. Fu JM, Satterstrom FK, Peng M, Brand H, Collins RL, Dong S, Wamsley B, Klei L, Wang L, Hao SP, Stevens CR, Cusick C, Babadi M, Banks E, Collins B, Dodge S, Gabriel SB, Gauthier L, Lee SK, Liang L, Ljungdahl A, Mahjani B, Sloofman L, Smirnov AN, Barbosa M, Betancur C, Brusco A, Chung BHY, Cook EH, Cuccaro ML, Domenici E, Ferrero GB, Gargus JJ, Herman GE, Hertz-Picciotto I, Maciel P, Manoach DS, Passos-Bueno MR, Persico AM, Renieri A, Sutcliffe JS, Tassone F, Trabetti E, Campos G, Cardaropoli S, Carli D, Chan MCY, Fallerini C, Giorgio E, Girardi AC, Hansen-Kiss E, Lee SL, Lintas C, Ludena Y, Nguyen R, Pavinato L, Pericak-Vance M, Pessah IN, Schmidt RJ, Smith M, Costa CIS, Trajkova S, Wang JYT, Yu MHC, Autism Sequencing Consortium (ASC), Broad Institute Center for Common Disease Genomics (Broad-CCDG), iPSYCH-BROAD Consortium, Cutler DJ, De Rubeis S, Buxbaum JD, Daly MJ, Devlin B, Roeder K, Sanders SJ, Talkowski ME. PMID: 35982160; PMCID: PMC9653013.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    8. The seizure-inducing plastic explosive RDX inhibits the α1β2γ2 GABAA receptor. Ann Clin Transl Neurol. 2022 05; 9(5):600-609. Pressly B, Lee RD, Singh V, Pessah IN, Wulff H. PMID: 35324073; PMCID: PMC9082378.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium. Front Neurosci. 2021; 15:766826. Sethi S, Keil Stietz KP, Valenzuela AE, Klocke CR, Silverman JL, Puschner B, Pessah IN, Lein PJ. PMID: 34938155; PMCID: PMC8685320.
      View in: PubMed   Mentions: 13  
    10. Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polychlorinated Biphenyls Mixture in the Juvenile Mouse. Front Neurosci. 2021; 15:766802. Keil Stietz KP, Sethi S, Klocke CR, de Ruyter TE, Wilson MD, Pessah IN, Lein PJ. PMID: 34924936; PMCID: PMC8678536.
      View in: PubMed   Mentions: 8  
    11. Marine and Anthropogenic Bromopyrroles Alter Cellular Ca2+ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic Reticulum Ca2+-ATPase. Environ Sci Technol. 2021 12 07; 55(23):16023-16033. Zheng J, Antrobus S, Feng W, Purdy TN, Moore BS, Pessah IN. PMID: 34788016; PMCID: PMC8813095.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Surfactant cocamide monoethanolamide causes eye irritation by activating nociceptor TRPV1 channels. Br J Pharmacol. 2021 09; 178(17):3448-3462. Zhao F, Wang S, Li Y, Wang J, Wang Y, Zhang C, Li Y, Huang L, Yu Y, Zheng J, Yu B, Pessah IN, Cao Z. PMID: 33837959.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Corrigendum: Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome. Front Mol Biosci. 2021; 8:695407. Holm KN, Herren AW, Taylor SL, Randol JL, Kim K, Espinal G, Martínez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. PMID: 34055898; PMCID: PMC8152804.
      View in: PubMed   Mentions:
    14. Structure-Activity Relationship of Neuroactive Steroids, Midazolam, and Perampanel Toward Mitigating Tetramine-Triggered Activity in Murine Hippocampal Neuronal Networks. Toxicol Sci. 2021 04 12; 180(2):325-341. Antrobus S, Pressly B, Nik AM, Wulff H, Pessah IN. PMID: 33483729; PMCID: PMC8599726.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    15. Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome. Front Mol Biosci. 2020; 7:600840. Holm KN, Herren AW, Taylor SL, Randol JL, Kim K, Espinal G, Martiínez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. PMID: 33585555; PMCID: PMC7879451.
      View in: PubMed   Mentions: 5  
    16. Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples. Regul Toxicol Pharmacol. 2021 Mar; 120:104842. Holland EB, Pessah IN. PMID: 33346014; PMCID: PMC8366267.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    17. Ryanodine Receptor Type 2: A Molecular Target for Dichlorodiphenyltrichloroethane- and Dichlorodiphenyldichloroethylene-Mediated Cardiotoxicity. Toxicol Sci. 2020 11 01; 178(1):159-172. Truong KM, Feng W, Pessah IN. PMID: 32894766; PMCID: PMC7850024.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    18. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice. Mol Pharmacol. 2020 10; 98(4):351-363. Aleman M, Zhang R, Feng W, Qi L, Lopez JR, Crowe C, Dong Y, Cherednichenko G, Pessah IN. PMID: 32764093; PMCID: PMC7491310.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. Sex-specific alterations in whole body energetics and voluntary activity in heterozygous R163C malignant hyperthermia-susceptible mice. FASEB J. 2020 06; 34(6):8721-8733. Rutkowsky JM, Knotts TA, Allen PD, Pessah IN, Ramsey JJ. PMID: 32367593; PMCID: PMC7383697.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. Cell. 2020 02 06; 180(3):568-584.e23. Satterstrom FK, Kosmicki JA, Wang J, Breen MS, De Rubeis S, An JY, Peng M, Collins R, Grove J, Klei L, Stevens C, Reichert J, Mulhern MS, Artomov M, Gerges S, Sheppard B, Xu X, Bhaduri A, Norman U, Brand H, Schwartz G, Nguyen R, Guerrero EE, Dias C, Autism Sequencing Consortium, iPSYCH-Broad Consortium, Betancur C, Cook EH, Gallagher L, Gill M, Sutcliffe JS, Thurm A, Zwick ME, Børglum AD, State MW, Cicek AE, Talkowski ME, Cutler DJ, Devlin B, Sanders SJ, Roeder K, Daly MJ, Buxbaum JD. PMID: 31981491; PMCID: PMC7250485.
      View in: PubMed   Mentions: 816     Fields:    Translation:HumansCells
    21. Additional Safety Assessments Needed for Diamide Insecticides. Toxicol Sci. 2019 Oct 01; 171(2):282. Pessah IN, Truong KM. PMID: 30830166; PMCID: PMC6760268.
      View in: PubMed   Mentions: 1     Fields:    
    22. Composition of the Intranuclear Inclusions of Fragile X-associated Tremor/Ataxia Syndrome. Acta Neuropathol Commun. 2019 09 03; 7(1):143. Ma L, Herren AW, Espinal G, Randol J, McLaughlin B, Martinez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. PMID: 31481131; PMCID: PMC6720097.
      View in: PubMed   Mentions: 30     Fields:    
    23. Interactions of Dichlorodiphenyltrichloroethane (DDT) and Dichlorodiphenyldichloroethylene (DDE) With Skeletal Muscle Ryanodine Receptor Type 1. Toxicol Sci. 2019 08 01; 170(2):509-524. Truong KM, Cherednichenko G, Pessah IN. PMID: 31127943; PMCID: PMC6657572.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice. Environ Pollut. 2019 Oct; 253:708-721. Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG. PMID: 31336350; PMCID: PMC6719698.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    25. Influence of Nanomolar Deltamethrin on the Hallmarks of Primary Cultured Cortical Neuronal Network and the Role of Ryanodine Receptors. Environ Health Perspect. 2019 06; 127(6):67003. Zheng J, Yu Y, Feng W, Li J, Liu J, Zhang C, Dong Y, Pessah IN, Cao Z. PMID: 31166131; PMCID: PMC6792378.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    26. Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta Neuropathol. 2019 09; 138(3):363-387. Pessah IN, Lein PJ, Seegal RF, Sagiv SK. PMID: 30976975; PMCID: PMC6708608.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    27. Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Activity at the Thyroid Hormone Receptor and Ryanodine Receptor. Environ Sci Technol. 2019 04 02; 53(7):3948-3958. Sethi S, Morgan RK, Feng W, Lin Y, Li X, Luna C, Koch M, Bansal R, Duffel MW, Puschner B, Zoeller RT, Lehmler HJ, Pessah IN, Lein PJ. PMID: 30821444; PMCID: PMC6457253.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    28. Comparison of Chlorantraniliprole and Flubendiamide Activity Toward Wild-Type and Malignant Hyperthermia-Susceptible Ryanodine Receptors and Heat Stress Intolerance. Toxicol Sci. 2019 02 01; 167(2):509-523. Truong KM, Pessah IN. PMID: 30329129; PMCID: PMC6358238.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    29. Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology. 2019 01; 70:112-121. Zheng J, Chen J, Zou X, Zhao F, Guo M, Wang H, Zhang T, Zhang C, Feng W, Pessah IN, Cao Z. PMID: 30458186; PMCID: PMC6342622.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    30. Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. Genes Brain Behav. 2019 01; 18(1):e12526. Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. PMID: 30311737; PMCID: PMC6540090.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    31. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 11; 126(11):117004. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. PMID: 30465702; PMCID: PMC6371714.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansPHPublic Health
    32. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 Jul 03; 52(13):7594. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. PMID: 29916692.
      View in: PubMed   Mentions:    Fields:    
    33. Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 05 01; 52(9):5469-5478. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. PMID: 29617551; PMCID: PMC6195434.
      View in: PubMed   Mentions: 9     Fields:    Translation:PHPublic Health
    34. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int. 2018 Jun; 25(17):16508-16521. Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. PMID: 29322390; PMCID: PMC6015536.
      View in: PubMed   Mentions: 19     Fields:    Translation:PHPublic Health
    35. Enantioselectivity of 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Atropisomers toward Ryanodine Receptors (RyRs) and Their Influences on Hippocampal Neuronal Networks. Environ Sci Technol. 2017 Dec 19; 51(24):14406-14416. Feng W, Zheng J, Robin G, Dong Y, Ichikawa M, Inoue Y, Mori T, Nakano T, Pessah IN. PMID: 29131945; PMCID: PMC6251309.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    36. Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison. Aquat Toxicol. 2017 Nov; 192:105-115. Holland EB, Goldstone JV, Pessah IN, Whitehead A, Reid NM, Karchner SI, Hahn ME, Nacci DE, Clark BW, Stegeman JJ. PMID: 28942070; PMCID: PMC5662517.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    37. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nat Neurosci. 2017 09; 20(9):1217-1224. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol MJ, Carracedo A, Kolevzon A, Hultman CM, Weiss LA, Fromer M, Chiocchetti AG, Freitag CM, Autism Sequencing Consortium, Church GM, Scherer SW, Buxbaum JD, Walsh CA. PMID: 28714951; PMCID: PMC5672813.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansCells
    38. Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 07 15; 26(14):2649-2666. Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN. PMID: 28444183; PMCID: PMC5886271.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    39. Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472. Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. PMID: 28411375; PMCID: PMC5808876.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    40. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Mol Pharmacol. 2017 07; 92(1):88-99. Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. PMID: 28428226; PMCID: PMC5452057.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    41. Divergent Mechanisms Leading to Signaling Dysfunction in Embryonic Muscle by Bisphenol A and Tetrabromobisphenol A. Mol Pharmacol. 2017 04; 91(4):428-436. Zhang R, Pessah IN. PMID: 28143888; PMCID: PMC5363716.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    42. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep. 2016 12 13; 17(11):3035-3048. Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. PMID: 27974215; PMCID: PMC5206988.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    43. Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures. Neurotoxicology. 2017 01; 58:11-22. Cao Z, Xu J, Hulsizer S, Cui Y, Dong Y, Pessah IN. PMID: 27984050; PMCID: PMC5303550.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    44. An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors. Toxicol Sci. 2017 01; 155(1):170-181. Holland EB, Feng W, Zheng J, Dong Y, Li X, Lehmler HJ, Pessah IN. PMID: 27655348; PMCID: PMC5216651.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    45. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. PMID: 27467073; PMCID: PMC5063690.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    46. In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):E2460-8. Ronjat M, Feng W, Dardevet L, Dong Y, Al Khoury S, Chatelain FC, Vialla V, Chahboun S, Lesage F, Darbon H, Pessah IN, De Waard M. PMID: 27071086; PMCID: PMC4855579.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    47. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61. Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. PMID: 26937944; PMCID: PMC4821808.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    48. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. PMID: 25882826; PMCID: PMC4466064.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    49. Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture. Mol Pharmacol. 2015 Apr; 87(4):595-605. Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. PMID: 25583085; PMCID: PMC4366799.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    50. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics. 2015 Jan; 12(1):234-49. Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. PMID: 25256961; PMCID: PMC4322077.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    51. Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA. Aquat Toxicol. 2015 Feb; 159:156-66. Fritsch EB, Stegeman JJ, Goldstone JV, Nacci DE, Champlin D, Jayaraman S, Connon RE, Pessah IN. PMID: 25546006; PMCID: PMC4300256.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    52. Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome. J Neurodev Disord. 2014; 6(1):25. Berman RF, Buijsen RA, Usdin K, Pintado E, Kooy F, Pretto D, Pessah IN, Nelson DL, Zalewski Z, Charlet-Bergeurand N, Willemsen R, Hukema RK. PMID: 25136376; PMCID: PMC4135345.
      View in: PubMed   Mentions: 36     Fields:    
    53. Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle. J Biol Chem. 2014 Jul 04; 289(27):19180-90. Altamirano F, Eltit JM, Robin G, Linares N, Ding X, Pessah IN, Allen PD, López JR. PMID: 24847052; PMCID: PMC4081953.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    54. Nanomolar bifenthrin alters synchronous Ca2+ oscillations and cortical neuron development independent of sodium channel activity. Mol Pharmacol. 2014 Apr; 85(4):630-9. Cao Z, Cui Y, Nguyen HM, Jenkins DP, Wulff H, Pessah IN. PMID: 24482397; PMCID: PMC3965893.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    55. PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicol Sci. 2014 Apr; 138(2):379-92. Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. PMID: 24385416; PMCID: PMC4007107.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
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    61. Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biol Psychiatry. 2013 Aug 01; 74(3):204-11. Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. PMID: 23623455; PMCID: PMC3755347.
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    63. Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion. J Biol Chem. 2013 May 10; 288(19):13831-41. Cao Z, Hulsizer S, Cui Y, Pretto DL, Kim KH, Hagerman PJ, Tassone F, Pessah IN. PMID: 23553633; PMCID: PMC3650419.
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    66. Triclosan impairs swimming behavior and alters expression of excitation-contraction coupling proteins in fathead minnow (Pimephales promelas). Environ Sci Technol. 2013 Feb 19; 47(4):2008-17. Fritsch EB, Connon RE, Werner I, Davies RE, Beggel S, Feng W, Pessah IN. PMID: 23305567; PMCID: PMC3640625.
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    67. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. FASEB J. 2013 Mar; 27(3):991-1000. Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. PMID: 23159934; PMCID: PMC3574284.
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    74. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. PMID: 22889812; PMCID: PMC3529644.
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    76. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice. PLoS One. 2012; 7(6):e38911. Koenig CM, Walker CK, Qi L, Pessah IN, Berman RF. PMID: 22719983; PMCID: PMC3374803.
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    77. Signaling defects in iPSC-derived fragile X premutation neurons. Hum Mol Genet. 2012 Sep 01; 21(17):3795-805. Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. PMID: 22641815; PMCID: PMC3412379.
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    81. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environ Health Perspect. 2012 Jul; 120(7):944-51. Shelton JF, Hertz-Picciotto I, Pessah IN. PMID: 22534084; PMCID: PMC3404662.
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    88. Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. Neurotoxicology. 2011 Dec; 32(6):981-5. Kim KH, Pessah IN. PMID: 21571002; PMCID: PMC3181005.
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    104. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62. Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. PMID: 20926377; PMCID: PMC2992278.
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    105. Altered T cell responses in children with autism. Brain Behav Immun. 2011 Jul; 25(5):840-9. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. PMID: 20833247; PMCID: PMC3039713.
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    124. Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation. Toxicol Appl Pharmacol. 2009 Jun 01; 237(2):168-77. Kim KH, Inan SY, Berman RF, Pessah IN. PMID: 19289137; PMCID: PMC2693412.
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    125. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. J Neuroimmunol. 2009 Mar 31; 208(1-2):130-5. Ashwood P, Schauer J, Pessah IN, Van de Water J. PMID: 19211157; PMCID: PMC2692510.
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    126. The skeletal L-type Ca(2+) current is a major contributor to excitation-coupled Ca(2+) entry. J Gen Physiol. 2009 Jan; 133(1):79-91. Bannister RA, Pessah IN, Beam KG. PMID: 19114636; PMCID: PMC2606935.
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    127. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chem Res Toxicol. 2009 Jan; 22(1):201-7. Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. PMID: 18954145; PMCID: PMC2662366.
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    128. Increased IgG4 levels in children with autism disorder. Brain Behav Immun. 2009 Mar; 23(3):389-95. Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. PMID: 19136055; PMCID: PMC2696343.
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    129. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J Neuroimmunol. 2008 Nov 15; 204(1-2):149-53. Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. PMID: 18762342; PMCID: PMC2615583.
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    130. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Res. 2008 Oct; 1(5):275-83. Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. PMID: 19343198; PMCID: PMC2663897.
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    131. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environ Health Perspect. 2009 Mar; 117(3):426-35. Yang D, Kim KH, Phimister A, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PR, Anderson KA, Wayman G, Pessah IN, Lein PJ. PMID: 19337518; PMCID: PMC2661913.
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    132. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect. 2008 Sep; 116(9):1203-10. Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD. PMID: 18795164; PMCID: PMC2535623.
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    133. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain Behav Immun. 2009 Jan; 23(1):124-33. Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. PMID: 18762240; PMCID: PMC2636576.
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    134. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun. 2008 Oct 24; 375(3):331-5. Vogel CF, Goth SR, Dong B, Pessah IN, Matsumura F. PMID: 18694728; PMCID: PMC2583959.
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    135. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008 Jun; 1(3):169-78. Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. PMID: 19132145; PMCID: PMC2614877.
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    136. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. PMID: 18394707; PMCID: PMC2475601.
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    137. Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes. Biophys J. 2008 Apr 15; 94(8):3023-34. Gach MP, Cherednichenko G, Haarmann C, Lopez JR, Beam KG, Pessah IN, Franzini-Armstrong C, Allen PD. PMID: 18192372; PMCID: PMC2275671.
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    138. Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol. 2008 Apr; 73(4):1203-12. Cherednichenko G, Ward CW, Feng W, Cabrales E, Michaelson L, Samso M, López JR, Allen PD, Pessah IN. PMID: 18171728; PMCID: PMC2735873.
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    139. Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):988-93. Voss AA, Allen PD, Pessah IN, Perez CF. PMID: 18096513; PMCID: PMC2693413.
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    140. Gene expression changes in children with autism. Genomics. 2008 Jan; 91(1):22-9. Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR. PMID: 18006270.
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    141. Autism: maternally derived antibodies specific for fetal brain proteins. Neurotoxicology. 2008 Mar; 29(2):226-31. Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. PMID: 18078998; PMCID: PMC2305723.
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    142. Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice. Toxicol Sci. 2008 Feb; 101(2):294-309. Berman RF, Pessah IN, Mouton PR, Mav D, Harry J. PMID: 17977901.
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    143. Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. J Biol Chem. 2007 Dec 28; 282(52):37471-8. Yang T, Allen PD, Pessah IN, Lopez JR. PMID: 17942409.
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    144. Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium. 2008 Mar; 43(3):307-14. Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. PMID: 17707505; PMCID: PMC2288792.
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    145. Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells. J Pharmacol Exp Ther. 2007 Oct; 323(1):381-90. Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. PMID: 17640951.
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    146. Hemicalcin, a new toxin from the Iranian scorpion Hemiscorpius lepturus which is active on ryanodine-sensitive Ca2+ channels. Biochem J. 2007 May 15; 404(1):89-96. Shahbazzadeh D, Srairi-Abid N, Feng W, Ram N, Borchani L, Ronjat M, Akbari A, Pessah IN, De Waard M, El Ayeb M. PMID: 17291197; PMCID: PMC1868827.
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    147. Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7646-51. Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. PMID: 17460041; PMCID: PMC1855918.
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    148. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? J Autism Dev Disord. 2008 Jan; 38(1):169-75. Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. PMID: 17347881.
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    149. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007 Mar 23; 282(12):8667-77. Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN. PMID: 17237236.
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    150. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. PMID: 17182726.
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    151. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75. Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. PMID: 17122579.
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    152. Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). Neurotoxicology. 2007 Jul; 28(4):770-9. Ta TA, Pessah IN. PMID: 17023049; PMCID: PMC2274001.
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    153. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. J Med Chem. 2006 Jul 27; 49(15):4497-511. Masuno MN, Pessah IN, Olmstead MM, Molinski TF. PMID: 16854055; PMCID: PMC3987770.
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    154. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environ Health Perspect. 2006 Jul; 114(7):1083-91. Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. PMID: 16835063; PMCID: PMC1513334.
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    155. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect. 2006 Jul; 114(7):1119-25. Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. PMID: 16835068; PMCID: PMC1513329.
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    156. Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem. 2006 Jul 28; 281(30):21022-21031. Fessenden JD, Feng W, Pessah IN, Allen PD. PMID: 16737973.
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    157. Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J Biol Chem. 2006 Apr 14; 281(15):10042-8. Lee EH, Cherednichenko G, Pessah IN, Allen PD. PMID: 16484216.
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    158. Heptachlor epoxide induces a non-capacitative type of Ca2+ entry and immediate early gene expression in mouse hepatoma cells. Toxicology. 2006 Mar 15; 220(2-3):218-31. Hansen ME, Pessah IN, Matsumura F. PMID: 16469423.
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    159. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chem Res Toxicol. 2006 Jan; 19(1):92-101. Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. PMID: 16411661.
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    160. Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression. J Immunol Methods. 2006 Jan 20; 308(1-2):179-91. Goth SR, Chu RA, Pessah IN. PMID: 16406060.
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    161. Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicol Teratol. 2006 Jan-Feb; 28(1):74-85. Roegge CS, Morris JR, Villareal S, Wang VC, Powers BE, Klintsova AY, Greenough WT, Pessah IN, Schantz SL. PMID: 16309888.
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    162. Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB J. 2006 Feb; 20(2):329-30. Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. PMID: 16284304.
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    163. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors. Mol Pharmacol. 2006 Feb; 69(2):532-8. Ta TA, Feng W, Molinski TF, Pessah IN. PMID: 16249374.
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    164. Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect. 2005 Oct; 113(10):1437-46. Dietrich KN, Eskenazi B, Schantz S, Yolton K, Rauh VA, Johnson CB, Alkon A, Canfield RL, Pessah IN, Berman RF. PMID: 16203260; PMCID: PMC1281293.
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    165. Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish. Toxicol Sci. 2005 Dec; 88(2):400-11. Kostyniak PJ, Hansen LG, Widholm JJ, Fitzpatrick RD, Olson JR, Helferich JL, Kim KH, Sable HJ, Seegal RF, Pessah IN, Schantz SL. PMID: 16177234.
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    166. Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. J Biol Chem. 2005 Nov 04; 280(44):36994-7004. Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN. PMID: 16120606.
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    167. Ryanodine receptor-mediated rapid increase in intracellular calcium induced by 7,8-benzo(a)pyrene quinone in human and murine leukocytes. Toxicol Sci. 2005 Oct; 87(2):419-26. Gao J, Voss AA, Pessah IN, Lauer FT, Penning TM, Burchiel SW. PMID: 16049270.
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    168. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon. 2005 May; 45(6):727-33. Inceoglu B, Lango J, Pessah IN, Hammock BD. PMID: 15804521.
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    169. Using 3D animations to teach intracellular signal transduction mechanisms: taking the arrows out of cells. J Vet Med Educ. 2005; 32(1):72-8. Buchanan MF, Carter WC, Cowgill LM, Hurley DJ, Lewis SJ, MacLeod JN, Melton TR, Moore JN, Pessah I, Roberson M, Robertson TP, Smith ML, Vandenplas ML. PMID: 15834824.
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    170. 1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas). Antagonists of the RyR1-FKBP12 Ca2+ Channel. Marine Drugs. 2004 Nov 25; 2(4):176-184. Masuno MM, Hoepker HA, Pessah PI, Molinski MT. .
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    171. Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C606-12. López JR, Linares N, Pessah IN, Allen PD. PMID: 15537710.
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    172. Conformational activation of Ca2+ entry by depolarization of skeletal myotubes. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15793-8. Cherednichenko G, Hurne AM, Fessenden JD, Lee EH, Allen PD, Beam KG, Pessah IN. PMID: 15505226; PMCID: PMC524834.
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    173. Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. J Biol Chem. 2004 Dec 17; 279(51):53028-35. Fessenden JD, Feng W, Pessah IN, Allen PD. PMID: 15469935.
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    174. Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia. Muscle Nerve. 2004 Sep; 30(3):356-65. Aleman M, Riehl J, Aldridge BM, Lecouteur RA, Stott JL, Pessah IN. PMID: 15318347.
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    175. Evidence for conformational coupling between two calcium channels. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12748-52. Paolini C, Fessenden JD, Pessah IN, Franzini-Armstrong C. PMID: 15310845; PMCID: PMC515124.
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    176. Identification of hyperreactive cysteines within ryanodine receptor type 1 by mass spectrometry. J Biol Chem. 2004 Aug 13; 279(33):34514-20. Voss AA, Lango J, Ernst-Russell M, Morin D, Pessah IN. PMID: 15197184.
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    177. NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. Circ Res. 2004 Mar 05; 94(4):478-86. Cherednichenko G, Zima AV, Feng W, Schaefer S, Blatter LA, Pessah IN. PMID: 14699012.
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    178. Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscle. J Biol Chem. 2004 Feb 13; 279(7):5781-7. Ward CW, Feng W, Tu J, Pessah IN, Worley PK, Schneider MF. PMID: 14660561.
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    179. Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. Toxicol Sci. 2004 Jan; 77(1):72-82. Gafni J, Wong PW, Pessah IN. PMID: 14600284.
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    180. Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C179-89. Lee EH, Lopez JR, Li J, Protasi F, Pessah IN, Kim DH, Allen PD. PMID: 13679303.
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    181. Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. J Biol Chem. 2003 Sep 26; 278(39):37822-31. Estève E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M. PMID: 12869557.
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    182. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol Appl Pharmacol. 2003 Jul 01; 190(1):72-86. Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. PMID: 12831785.
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    183. Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem. 2003 Aug 01; 278(31):28727-35. Fessenden JD, Perez CF, Goth S, Pessah IN, Allen PD. PMID: 12761215.
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    184. Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem. 2003 Jul 11; 278(28):25722-30. Yang T, Ta TA, Pessah IN, Allen PD. PMID: 12732639.
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    185. RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophys J. 2003 Apr; 84(4):2655-63. Perez CF, Voss A, Pessah IN, Allen PD. PMID: 12668474; PMCID: PMC1302832.
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    186. Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106. Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN. PMID: 12586831.
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    187. One scorpion, two venoms: prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):922-7. Inceoglu B, Lango J, Jing J, Chen L, Doymaz F, Pessah IN, Hammock BD. PMID: 12552107; PMCID: PMC298702.
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    188. Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem. 2002 Nov 22; 277(47):44722-30. Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN. PMID: 12223488.
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    189. Redox sensing properties of the ryanodine receptor complex. Front Biosci. 2002 May 01; 7:a72-9. Pessah IN, Kim KH, Feng W. PMID: 11991848.
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    190. Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J. 2002 May; 82(5):2428-35. O'Brien JJ, Feng W, Allen PD, Chen SR, Pessah IN, Beam KG. PMID: 11964231; PMCID: PMC1302033.
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    191. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. J Nat Prod. 2002 Mar; 65(3):249-54. Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski TF. PMID: 11908959.
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    192. Detection of redox sensor of ryanodine receptor complexes. Methods Enzymol. 2002; 353:240-53. Feng W, Pessah IN. PMID: 12078499.
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    193. Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J. 2001 Dec; 81(6):3216-30. Ward CW, Protasi F, Castillo D, Wang Y, Chen SR, Pessah IN, Allen PD, Schneider MF. PMID: 11720987; PMCID: PMC1301781.
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    194. Ryanodine receptor acts as a sensor for redox stress. Pest Manag Sci. 2001 Oct; 57(10):941-5. Pessah IN. PMID: 11695187.
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    195. Malignant hyperthermia. Best Practice & Research Clinical Anaesthesiology. 2001 Jun 1; 15(2):277-288. Pessah PI, Allen AP. .
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    196. Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors. J Neurosci. 2001 Jun 01; 21(11):3860-70. Haak LL, Song LS, Molinski TF, Pessah IN, Cheng H, Russell JT. PMID: 11356874; PMCID: PMC6762718.
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    197. A bioactive metabolite of benzo[a]pyrene, benzo[a]pyrene-7,8-dione, selectively alters microsomal Ca2+ transport and ryanodine receptor function. Mol Pharmacol. 2001 Mar; 59(3):506-13. Pessah IN, Beltzner C, Burchiel SW, Sridhar G, Penning T, Feng W. PMID: 11179446.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    198. Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2865-70. Fessenden JD, Chen L, Wang Y, Paolini C, Franzini-Armstrong C, Allen PD, Pessah IN. PMID: 11226332; PMCID: PMC30231.
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    199. ortho-substituted PCB95 alters intracellular calcium signaling and causes cellular acidification in PC12 cells by an immunophilin-dependent mechanism. J Neurochem. 2001 Jan; 76(2):450-63. Wong PW, Garcia EF, Pessah IN. PMID: 11208908.
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    200. Transmembrane redox sensor of ryanodine receptor complex. J Biol Chem. 2000 Nov 17; 275(46):35902-7. Feng W, Liu G, Allen PD, Pessah IN. PMID: 10998414.
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    201. Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J. 2000 Nov; 79(5):2509-25. Fessenden JD, Wang Y, Moore RA, Chen SR, Allen PD, Pessah IN. PMID: 11053126; PMCID: PMC1301134.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    202. Role of the sarcoplasmic reticulum in regulating the activity-dependent expression of the glycogen phosphorylase gene in contractile skeletal muscle cells. J Cell Physiol. 2000 Nov; 185(2):184-99. Vali S, Carlsen R, Pessah I, Gorin F. PMID: 11025440.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    203. Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol Cell. 2000 Aug; 6(2):421-31. Kiselyov KI, Shin DM, Wang Y, Pessah IN, Allen PD, Muallem S. PMID: 10983988.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    204. Characterization of [(3)H]ryanodine binding sites in mammalian lung. Arch Biochem Biophys. 2000 Jul 01; 379(1):109-18. Wild JS, Giri SN, Moore R, Pessah IN. PMID: 10864448.
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    205. Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4380-5. González A, Kirsch WG, Shirokova N, Pizarro G, Brum G, Pessah IN, Stern MD, Cheng H, Ríos E. PMID: 10759554; PMCID: PMC18250.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    206. Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett. 2000 Mar 10; 469(2-3):179-85. Fajloun Z, Kharrat R, Chen L, Lecomte C, Di Luccio E, Bichet D, El Ayeb M, Rochat H, Allen PD, Pessah IN, De Waard M, Sabatier JM. PMID: 10713267.
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    207. HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes. Am J Physiol Cell Physiol. 2000 Mar; 278(3):C619-26. Wang Y, Fraefel C, Protasi F, Moore RA, Fessenden JD, Pessah IN, DiFrancesco A, Breakefield X, Allen PD. PMID: 10712251.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    208. Functional role of hyperreactive sulfhydryl moieties within the ryanodine receptor complex. Antioxid Redox Signal. 2000; 2(1):17-25. Pessah IN, Feng W. PMID: 11232595.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    209. Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner. J Biol Chem. 1999 Nov 12; 274(46):32603-12. Chen L, Molinski TF, Pessah IN. PMID: 10551814.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    210. Site-selective modification of hyperreactive cysteines of ryanodine receptor complex by quinones. Mol Pharmacol. 1999 May; 55(5):821-31. Feng W, Liu G, Xia R, Abramson JJ, Pessah IN. PMID: 10220560.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    211. Mechanisms of delta-hexachlorocyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function. J Pharmacol Exp Ther. 1999 Apr; 289(1):477-85. Buck ED, Lachnit WG, Pessah IN. PMID: 10087040.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    212. Mechanisms of delta-hexachlorocyclohexane toxicity: II. Evidence for Ca2+-dependent K+-selective ionophore activity. J Pharmacol Exp Ther. 1999 Apr; 289(1):486-93. Buck ED, Pessah IN. PMID: 10087041.
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    213. Functional interaction between InsP3 receptors and store-operated Htrp3 channels. Nature. 1998 Dec 03; 396(6710):478-82. Kiselyov K, Xu X, Mozhayeva G, Kuo T, Pessah I, Mignery G, Zhu X, Birnbaumer L, Muallem S. PMID: 9853757.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    214. Inositol-1,4,5-trisphosphate receptor-mediated Ca mobilization is not required for cerebellar long-term depression in reduced preparations. J Neurophysiol. 1998 Dec; 80(6):2963-74. Narasimhan K, Pessah IN, Linden DJ. PMID: 9862899.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    215. A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol. 1998 Feb 23; 140(4):843-51. Moore RA, Nguyen H, Galceran J, Pessah IN, Allen PD. PMID: 9472036; PMCID: PMC2141755.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    216. Symposium overview: toxicity of non-coplanar PCBs. Toxicol Sci. 1998 Jan; 41(1):49-61. Fischer LJ, Seegal RF, Ganey PE, Pessah IN, Kodavanti PR. PMID: 9520341.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    217. Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron. 1997 Sep; 19(3):723-33. Gafni J, Munsch JA, Lam TH, Catlin MC, Costa LG, Molinski TF, Pessah IN. PMID: 9331361.
      View in: PubMed   Mentions: 188     Fields:    Translation:AnimalsCells
    218. Ryanodine receptor type III (Ry3R) identification in mouse parotid acini. Properties and modulation of [3H]ryanodine-binding sites. J Biol Chem. 1997 Jun 20; 272(25):15687-96. DiJulio DH, Watson EL, Pessah IN, Jacobson KL, Ott SM, Buck ED, Singh JC. PMID: 9188460.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    219. Ortho-substituted polychlorinated biphenyls alter microsomal calcium transport by direct interaction with ryanodine receptors of mammalian brain. J Biol Chem. 1997 Jun 13; 272(24):15145-53. Wong PW, Brackney WR, Pessah IN. PMID: 9182535.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    220. Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. Mol Pharmacol. 1997 May; 51(5):693-702. Wong PW, Pessah IN. PMID: 9145907.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    221. Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function. J Biol Chem. 1997 Mar 14; 272(11):7360-7. Buck ED, Nguyen HT, Pessah IN, Allen PD. PMID: 9054435.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    222. Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C601-14. Pessah IN, Molinski TF, Meloy TD, Wong P, Buck ED, Allen PD, Mohr FC, Mack MM. PMID: 9124304.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    223. Ortho-substituted 2,2',3,5',6-pentachlorobiphenyl (PCB 95) alters rat hippocampal ryanodine receptors and neuroplasticity in vitro: evidence for altered hippocampal function. Neurotoxicology. 1997; 18(2):443-56. Wong PW, Joy RM, Albertson TE, Schantz SL, Pessah IN. PMID: 9291493.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    224. Long-term effects of developmental exposure to 2,2',3,5',6-pentachlorobiphenyl (PCB 95) on locomotor activity, spatial learning and memory and brain ryanodine binding. Neurotoxicology. 1997; 18(2):457-67. Schantz SL, Seo BW, Wong PW, Pessah IN. PMID: 9291494.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    225. Bastadin 20 and bastadin O-sulfate esters from Ianthella basta: novel modulators of the Ry1R FKBP12 receptor complex. J Nat Prod. 1996 Dec; 59(12):1121-7. Franklin MA, Penn SG, Lebrilla CB, Lam TH, Pessah IN, Molinski TF. PMID: 8988595.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    226. Complex pharmacology of malignant hyperthermia. Anesthesiology. 1996 Jun; 84(6):1275-9. Pessah IN, Lynch C, Gronert GA. PMID: 8669666.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    227. Ortho-substituted polychlorinated biphenyls alter calcium regulation by a ryanodine receptor-mediated mechanism: structural specificity toward skeletal- and cardiac-type microsomal calcium release channels. Mol Pharmacol. 1996 Apr; 49(4):740-51. Wong PW, Pessah IN. PMID: 8609904.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    228. Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature. 1996 Mar 07; 380(6569):72-5. Nakai J, Dirksen RT, Nguyen HT, Pessah IN, Beam KG, Allen PD. PMID: 8598910.
      View in: PubMed   Mentions: 206     Fields:    Translation:AnimalsCells
    229. The delta isomer of hexachlorocyclohexane induces rapid release of the myo-inositol-1,4,5-trisphosphate-sensitive Ca2+ store and blocks capacitative Ca2+ entry in rat basophilic leukemia cells. Mol Pharmacol. 1995 Sep; 48(3):512-22. Mohr FC, Alojipan SV, Dunston SK, Pessah IN. PMID: 7565633.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    230. Iron(II) is a modulator of ryanodine-sensitive calcium channels of cardiac muscle sarcoplasmic reticulum. Toxicol Appl Pharmacol. 1995 Jan; 130(1):57-66. Kim E, Giri SN, Pessah IN. PMID: 7530865.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    231. Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls. J Biol Chem. 1994 Dec 30; 269(52):33028-34. Liu G, Pessah IN. PMID: 7806531.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    232. Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J Biol Chem. 1994 Sep 16; 269(37):23236-49. Mack MM, Molinski TF, Buck ED, Pessah IN. PMID: 8083229.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    233. Ryanodine and dihydropyridine binding patterns and ryanodine receptor mRNA levels in myopathic hamster heart. Am J Physiol. 1994 Sep; 267(3 Pt 2):H1205-13. Lachnit WG, Phillips M, Gayman KJ, Pessah IN. PMID: 8092287.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    234. Antithetical actions of mitoxantrone and doxorubicin on ryanodine-sensitive Ca++ release channels of rat cardiac sarcoplasmic reticulum: evidence for a competitive mechanism. J Pharmacol Exp Ther. 1994 Mar; 268(3):1212-21. Kim E, Giri SN, Pessah IN. PMID: 8138934.
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    235. Direct evidence for the existence and functional role of hyperreactive sulfhydryls on the ryanodine receptor-triadin complex selectively labeled by the coumarin maleimide 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin. Mol Pharmacol. 1994 Feb; 45(2):189-200. Liu G, Abramson JJ, Zable AC, Pessah IN. PMID: 8114670.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    236. Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. I. Multiple conformational states of the receptor in a microsomal preparation. Biochim Biophys Acta. 1993 Apr 08; 1147(1):105-14. Mohr FC, Hershey PE, Zimányi I, Pessah IN. PMID: 8385492.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    237. Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. II. Modulation of the receptor in permeabilized cells by the cytosolic compartment. Biochim Biophys Acta. 1993 Apr 08; 1147(1):115-24. Hershey PE, Pessah IN, Mohr FC. PMID: 8385493.
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    238. Porphyrin induced calcium release from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys. 1993 Mar; 301(2):396-403. Abramson JJ, Milne S, Buck E, Pessah IN. PMID: 7681662.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    239. Prolonged exercise reduces Ca2+ release in rat skeletal muscle sarcoplasmic reticulum. Pflugers Arch. 1993 Feb; 422(5):472-5. Favero TG, Pessah IN, Klug GA. PMID: 7682687.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    240. Ryanodine induces maturation of embryonic acetylcholinesterase forms in cultured quail myotubes. Life Sci. 1993; 52(15):1279-85. Pessah IN, Nieberg PS, Wilson BW. PMID: 7681926.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    241. Ryanodine induces persistent inactivation of the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol. 1992 Dec; 42(6):1049-57. Zimányi I, Buck E, Abramson JJ, Mack MM, Pessah IN. PMID: 1480132.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    242. Ryanodine stabilizes multiple conformational states of the skeletal muscle calcium release channel. J Biol Chem. 1992 Nov 25; 267(33):23560-7. Buck E, Zimanyi I, Abramson JJ, Pessah IN. PMID: 1331089.
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    243. Discrimination of multiple binding sites for antagonists of the calcium release channel complex of skeletal and cardiac sarcoplasmic reticulum. J Pharmacol Exp Ther. 1992 Sep; 262(3):1028-37. Mack WM, Zimányi I, Pessah IN. PMID: 1382127.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    244. Stereoselective modulation of ryanodine-sensitive calcium channels by the delta isomer of hexachlorocyclohexane (delta-HCH). J Pharmacol Exp Ther. 1992 Aug; 262(2):661-9. Pessah IN, Mohr FC, Schiedt M, Joy RM. PMID: 1380081.
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    245. Photooxidation of skeletal muscle sarcoplasmic reticulum induces rapid calcium release. Arch Biochem Biophys. 1992 Feb 01; 292(2):512-21. Stuart J, Pessah IN, Favero TG, Abramson JJ. PMID: 1531000.
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    246. Rose bengal activates the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys. 1992 Feb 01; 292(2):522-8. Xiong H, Buck E, Stuart J, Pessah IN, Salama G, Abramson JJ. PMID: 1309975.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    247. Etiology of sarcoplasmic reticulum calcium release channel lesions in doxorubicin-induced cardiomyopathy. Toxicology. 1992; 72(2):189-206. Pessah IN, Schiedt MJ, Shalaby MA, Mack M, Giri SN. PMID: 1314436.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    248. Calcium release channel of sarcoplasmic reticulum: an important target for doxorubicin-mediated cardiotoxicity. Adv Exp Med Biol. 1992; 311:409-10. Pessah IN. PMID: 1326869.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    249. Pharmacological characterization of the specific binding of [3H]ryanodine to rat brain microsomal membranes. Brain Res. 1991 Oct 11; 561(2):181-91. Zimanyi I, Pessah IN. PMID: 1666327.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    250. Characterization of multiple [3H]ryanodine binding sites on the Ca2+ release channel of sarcoplasmic reticulum from skeletal and cardiac muscle: evidence for a sequential mechanism in ryanodine action. Mol Pharmacol. 1991 May; 39(5):679-89. Pessah IN, Zimanyi I. PMID: 1851961.
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    251. Comparison of [3H]ryanodine receptors and Ca++ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum. J Pharmacol Exp Ther. 1991 Mar; 256(3):938-46. Zimányi I, Pessah IN. PMID: 1848635.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    252. Anthraquinone-sensitized Ca2+ release channel from rat cardiac sarcoplasmic reticulum: possible receptor-mediated mechanism of doxorubicin cardiomyopathy. Mol Pharmacol. 1990 Apr; 37(4):503-14. Pessah IN, Durie EL, Schiedt MJ, Zimanyi I. PMID: 2157959.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    253. Early over-expression of low-affinity [3H]ryanodine receptor sites in heavy sarcoplasmic reticulum fraction from dystrophic chicken pectoralis major. Biochim Biophys Acta. 1990 Mar 30; 1023(1):98-106. Pessah IN, Schiedt MJ. PMID: 2156566.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    254. Reactive disulfides trigger Ca2+ release from sarcoplasmic reticulum via an oxidation reaction. J Biol Chem. 1989 Dec 25; 264(36):21725-36. Zaidi NF, Lagenaur CF, Abramson JJ, Pessah I, Salama G. PMID: 2532212.
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    255. Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum. J Biol Chem. 1988 Dec 15; 263(35):18750-8. Abramson JJ, Buck E, Salama G, Casida JE, Pessah IN. PMID: 3198599.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    256. Partial characterization of specific cantharidin binding sites in mouse tissues. Mol Pharmacol. 1988 Jun; 33(6):706-12. Graziano MJ, Pessah IN, Matsuzawa M, Casida JE. PMID: 3380085.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    257. Structural aspects of ryanodine action and selectivity. J Med Chem. 1987 Apr; 30(4):710-6. Waterhouse AL, Pessah IN, Francini AO, Casida JE. PMID: 2435905.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    258. Ca2+-activated ryanodine binding: mechanisms of sensitivity and intensity modulation by Mg2+, caffeine, and adenine nucleotides. Mol Pharmacol. 1987 Mar; 31(3):232-8. Pessah IN, Stambuk RA, Casida JE. PMID: 2436032.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    259. Solubilization and separation of Ca2+-ATPase from the Ca2+-ryanodine receptor complex. Biochem Biophys Res Commun. 1986 Aug 29; 139(1):235-43. Pessah IN, Anderson KW, Casida JE. PMID: 2945551.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    260. Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles. J Biol Chem. 1986 Jul 05; 261(19):8643-8. Pessah IN, Francini AO, Scales DJ, Waterhouse AL, Casida JE. PMID: 3722165.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    261. Distribution, pharmacokinetics, and metabolism of [14C]2,4-diamino-6-(2-furyl)-s-triazine in various developmental stages of the house fly. Pesticide Biochemistry and Physiology. 1986 Jun 1; 25(3):306-318. Pessah PI, Menzer MR, Borkovec BA. .
      View in: Publisher Site   Mentions:
    262. The calcium-ryanodine receptor complex of skeletal and cardiac muscle. Biochem Biophys Res Commun. 1985 Apr 16; 128(1):449-56. Pessah IN, Waterhouse AL, Casida JE. PMID: 3985981.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    263. The interaction of organophosphate and carbamate insecticides with cholinesterases in the terrestrial pulmonate, Limax maximus. Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology. 1983 Jan 1; 74(2):291-297. Pessah PI, Sokolove SP. .
      View in: Publisher Site   Mentions:
    264. Determination and characterization of cholinesterases in localized tissues of the giant garden slugs Limax maximus (Linnaeus). Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology. 1983 Jan 1; 74(2):281-289. Pessah PI, Sokolove SP. .
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    265. Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. J Biol Chem. 1981 Mar 25; 256(6):2843-50. Aronstam RS, Eldefrawi AT, Pessah IN, Daly JW, Albuquerque EX, Eldefrawi ME. PMID: 7204378.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    266. Reconstitution of N1-methylnicotinamide and p-aminohippuric acid transport in phospholipid vesicles with a protein fraction isolated from dog kidney membranes. Mol Pharmacol. 1979 Jul; 16(1):343-56. Holohan PD, Pessah NI, Pessah IN, Ross CR. PMID: 39247.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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