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Isaac Pessah

TitleInterim Dean
InstitutionUniversity of California Davis
DepartmentMolecular Biosciences
Address2203 VM3B
CA 95616
Phone530-752-6696
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zheng J, Chen J, Zou X, Zhao F, Guo M, Wang H, Zhang T, Zhang C, Feng W, Pessah IN, Cao Z. Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology. 2018 Nov 17; 70:112-121. PMID: 30458186.
      View in: PubMed
    2. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 Nov; 126(11):117004. PMID: 30465702.
      View in: PubMed
    3. Truong KM, Pessah IN. Comparison of chlorantraniliprole and flubendiamide activity towards wild type and malignant hyperthermia-susceptible ryanodine receptors and heat stress intolerance. Toxicol Sci. 2018 Oct 17. PMID: 30329129.
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    4. Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. Genes Brain Behav. 2018 Oct 12; e12526. PMID: 30311737.
      View in: PubMed
    5. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 Jun 19. PMID: 29916692.
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    6. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 May 01; 52(9):5469-5478. PMID: 29617551.
      View in: PubMed
    7. Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int. 2018 Jan 10. PMID: 29322390.
      View in: PubMed
    8. Feng W, Zheng J, Robin G, Dong Y, Ichikawa M, Inoue Y, Mori T, Nakano T, Pessah IN. Enantioselectivity of 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Atropisomers toward Ryanodine Receptors (RyRs) and Their Influences on Hippocampal Neuronal Networks. Environ Sci Technol. 2017 Dec 19; 51(24):14406-14416. PMID: 29131945.
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    9. Holland EB, Goldstone JV, Pessah IN, Whitehead A, Reid NM, Karchner SI, Hahn ME, Nacci DE, Clark BW, Stegeman JJ. Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison. Aquat Toxicol. 2017 Nov; 192:105-115. PMID: 28942070.
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    10. Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN. Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 07 15; 26(14):2649-2666. PMID: 28444183.
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    11. Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472. PMID: 28411375.
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    12. Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Mol Pharmacol. 2017 Jul; 92(1):88-99. PMID: 28428226.
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    13. Zhang R, Pessah IN. Divergent Mechanisms Leading to Signaling Dysfunction in Embryonic Muscle by Bisphenol A and Tetrabromobisphenol A. Mol Pharmacol. 2017 04; 91(4):428-436. PMID: 28143888.
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    14. Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep. 2016 12 13; 17(11):3035-3048. PMID: 27974215.
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    15. Cao Z, Xu J, Hulsizer S, Cui Y, Dong Y, Pessah IN. Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures. Neurotoxicology. 2017 01; 58:11-22. PMID: 27984050.
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    16. Holland EB, Feng W, Zheng J, Dong Y, Li X, Lehmler HJ, Pessah IN. An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors. Toxicol Sci. 2017 01; 155(1):170-181. PMID: 27655348.
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    17. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. PMID: 27467073.
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    18. Ronjat M, Feng W, Dardevet L, Dong Y, Al Khoury S, Chatelain FC, Vialla V, Chahboun S, Lesage F, Darbon H, Pessah IN, De Waard M. In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):E2460-8. PMID: 27071086; PMCID: PMC4855579 [Available on 10/26/16].
    19. Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61. PMID: 26937944; PMCID: PMC4821808 [Available on 04/05/17].
    20. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. PMID: 25882826; PMCID: PMC4466064.
    21. Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture. Mol Pharmacol. 2015 Apr; 87(4):595-605. PMID: 25583085; PMCID: PMC4366799.
    22. Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics. 2015 Jan; 12(1):234-49. PMID: 25256961; PMCID: PMC4322077.
    23. Fritsch EB, Stegeman JJ, Goldstone JV, Nacci DE, Champlin D, Jayaraman S, Connon RE, Pessah IN. Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA. Aquat Toxicol. 2015 Feb; 159:156-66. PMID: 25546006; PMCID: PMC4300256.
    24. Berman RF, Buijsen RA, Usdin K, Pintado E, Kooy F, Pretto D, Pessah IN, Nelson DL, Zalewski Z, Charlet-Bergeurand N, Willemsen R, Hukema RK. Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome. J Neurodev Disord. 2014; 6(1):25. PMID: 25136376; PMCID: PMC4135345.
    25. Altamirano F, Eltit JM, Robin G, Linares N, Ding X, Pessah IN, Allen PD, López JR. Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle. J Biol Chem. 2014 Jul 04; 289(27):19180-90. PMID: 24847052; PMCID: PMC4081953.
    26. Cao Z, Cui Y, Nguyen HM, Jenkins DP, Wulff H, Pessah IN. Nanomolar bifenthrin alters synchronous Ca2+ oscillations and cortical neuron development independent of sodium channel activity. Mol Pharmacol. 2014 Apr; 85(4):630-9. PMID: 24482397; PMCID: PMC3965893.
    27. Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicol Sci. 2014 Apr; 138(2):379-92. PMID: 24385416; PMCID: PMC4007107.
    28. Pretto DI, Kumar M, Cao Z, Cunningham CL, Durbin-Johnson B, Qi L, Berman R, Noctor SC, Hagerman RJ, Pessah IN, Tassone F. Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome. Neurobiol Aging. 2014 May; 35(5):1189-97. PMID: 24332449; PMCID: PMC4062976.
    29. Niknam Y, Feng W, Cherednichenko G, Dong Y, Joshi SN, Vyas SM, Lehmler HJ, Pessah IN. Structure-activity relationship of selected meta- and para-hydroxylated non-dioxin like polychlorinated biphenyls: from single RyR1 channels to muscle dysfunction. Toxicol Sci. 2013 Dec; 136(2):500-13. PMID: 24014653; PMCID: PMC3858193.
    30. Vogel CF, Wu D, Goth SR, Baek J, Lollies A, Domhardt R, Grindel A, Pessah IN. Aryl hydrocarbon receptor signaling regulates NF-?B RelB activation during dendritic-cell differentiation. Immunol Cell Biol. 2013 Oct; 91(9):568-75. PMID: 23999131; PMCID: PMC3806313.
    31. Fritsch EB, Pessah IN. Structure-activity relationship of non-coplanar polychlorinated biphenyls toward skeletal muscle ryanodine receptors in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol. 2013 Sep 15; 140-141:204-12. PMID: 23827775; PMCID: PMC3813431.
    32. Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biol Psychiatry. 2013 Aug 01; 74(3):204-11. PMID: 23623455; PMCID: PMC3755347.
    33. Lin YP, Pessah IN, Puschner B. Simultaneous determination of polybrominated diphenyl ethers and polychlorinated biphenyls by gas chromatography-tandem mass spectrometry in human serum and plasma. Talanta. 2013 Sep 15; 113:41-8. PMID: 23708622; PMCID: PMC3698050.
    34. Cao Z, Hulsizer S, Cui Y, Pretto DL, Kim KH, Hagerman PJ, Tassone F, Pessah IN. Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion. J Biol Chem. 2013 May 10; 288(19):13831-41. PMID: 23553633; PMCID: PMC3650419.
    35. Tassone F, Choudhary NS, Tassone F, Durbin-Johnson B, Hansen R, Hertz-Picciotto I, Pessah I. Identification of expanded alleles of the FMR1 Gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) study. J Autism Dev Disord. 2013 Mar; 43(3):530-9. PMID: 22767137; PMCID: PMC4596818.
    36. Fritsch EB, Connon RE, Werner I, Davies RE, Beggel S, Feng W, Pessah IN. Triclosan impairs swimming behavior and alters expression of excitation-contraction coupling proteins in fathead minnow (Pimephales promelas). Environ Sci Technol. 2013 Feb 19; 47(4):2008-17. PMID: 23305567; PMCID: PMC3640625.
    37. Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. FASEB J. 2013 Mar; 27(3):991-1000. PMID: 23159934; PMCID: PMC3574284.
    38. Koenig CM, Lango J, Pessah IN, Berman RF. Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice. Neurotoxicol Teratol. 2012 Nov-Dec; 34(6):571-80. PMID: 23022914; PMCID: PMC3501584.
    39. Kaplan ES, Cao Z, Hulsizer S, Tassone F, Berman RF, Hagerman PJ, Pessah IN. Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model. J Neurochem. 2012 Nov; 123(4):613-21. PMID: 22924671; PMCID: PMC3564636.
    40. Mitchell MM, Woods R, Chi LH, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder. Environ Mol Mutagen. 2012 Oct; 53(8):589-98. PMID: 22930557; PMCID: PMC3739306.
    41. Braunschweig D, Golub MS, Koenig CM, Qi L, Pessah IN, Van de Water J, Berman RF. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. J Neuroimmunol. 2012 Nov 15; 252(1-2):56-65. PMID: 22951357; PMCID: PMC4096980.
    42. Feng W, Hwang HS, Kryshtal DO, Yang T, Padilla IT, Tiwary AK, Puschner B, Pessah IN, Knollmann BC. Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin. Mol Pharmacol. 2012 Nov; 82(5):993-1000. PMID: 22918967; PMCID: PMC3477230.
    43. Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14158-63. PMID: 22891308; PMCID: PMC3435154.
    44. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²? dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. PMID: 22889812; PMCID: PMC3529644.
    45. Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. J Autism Dev Disord. 2012 Jul; 42(7):1435-45. PMID: 22012245; PMCID: PMC4871696.
    46. Koenig CM, Walker CK, Qi L, Pessah IN, Berman RF. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice. PLoS One. 2012; 7(6):e38911. PMID: 22719983; PMCID: PMC3374803.
    47. Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. Signaling defects in iPSC-derived fragile X premutation neurons. Hum Mol Genet. 2012 Sep 01; 21(17):3795-805. PMID: 22641815; PMCID: PMC3412379.
    48. Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8. PMID: 22547813; PMCID: PMC3356662.
    49. Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environ Health Perspect. 2012 Jul; 120(7):997-1002. PMID: 22534141; PMCID: PMC3404670.
    50. Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environ Health Perspect. 2012 Jul; 120(7):1003-9. PMID: 22534176; PMCID: PMC3404671.
    51. Shelton JF, Hertz-Picciotto I, Pessah IN. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environ Health Perspect. 2012 Jul; 120(7):944-51. PMID: 22534084; PMCID: PMC3404662.
    52. Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 01; 21(13):2923-35. PMID: 22466801; PMCID: PMC3373240.
    53. Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, LaSalle JM. Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Hum Mol Genet. 2012 Jun 01; 21(11):2399-411. PMID: 22343140; PMCID: PMC3349420.
    54. Barrientos GC, Feng W, Truong K, Matthaei KI, Yang T, Allen PD, Lopez JR, Pessah IN. Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle. J Biol Chem. 2012 Jan 20; 287(4):2863-76. PMID: 22139840; PMCID: PMC3267780.
    55. Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN. Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage. FASEB J. 2012 Mar; 26(3):1311-22. PMID: 22131268; PMCID: PMC3289506.
    56. Kim KH, Pessah IN. Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. Neurotoxicology. 2011 Dec; 32(6):981-5. PMID: 21571002; PMCID: PMC3181005.
    57. Tassone F, Qi L, Zhang W, Hansen RL, Pessah IN, Hertz-Picciotto I. MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism Res. 2011 Aug; 4(4):250-61. PMID: 21538940; PMCID: PMC3151322.
    58. Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51. PMID: 21482776; PMCID: PMC3084091.
    59. Ta TA, Koenig CM, Golub MS, Pessah IN, Qi L, Aronov PA, Berman RF. Bioaccumulation and behavioral effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice. Neurotoxicol Teratol. 2011 May-Jun; 33(3):393-404. PMID: 21334437; PMCID: PMC3543834.
    60. Hertz-Picciotto I, Bergman A, Fängström B, Rose M, Krakowiak P, Pessah I, Hansen R, Bennett DH. Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study. Environ Health. 2011 Jan 05; 10(1):1. PMID: 21205326; PMCID: PMC3029221.
    61. Lein PJ, Barnhart CD, Pessah IN. Acute hippocampal slice preparation and hippocampal slice cultures. Methods Mol Biol. 2011; 758:115-34. PMID: 21815062; PMCID: PMC3499947.
    62. Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN. Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Mol Pharmacol. 2011 Mar; 79(3):420-31. PMID: 21156754; PMCID: PMC3061367.
    63. Giulivi C, Zhang YF, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz-Picciotto I, Tassone F, Pessah IN. Mitochondrial dysfunction in autism. JAMA. 2010 Dec 01; 304(21):2389-96. PMID: 21119085.
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    64. Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environ Health Perspect. 2011 Apr; 119(4):519-26. PMID: 21106467; PMCID: PMC3080935.
    65. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J Neuroimmunol. 2011 Mar; 232(1-2):196-9. PMID: 21095018; PMCID: PMC3053074.
    66. Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN. Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice. J Biol Chem. 2011 Jan 07; 286(1):99-113. PMID: 20978128; PMCID: PMC3013050.
    67. Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 01; 20(1):64-79. PMID: 20935171; PMCID: PMC3000676.
    68. Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62. PMID: 20926377; PMCID: PMC2992278.
    69. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain Behav Immun. 2011 Jul; 25(5):840-9. PMID: 20833247; PMCID: PMC3039713.
    70. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav Immun. 2011 Jan; 25(1):40-5. PMID: 20705131; PMCID: PMC2991432.
    71. Feng W, Cherednichenko G, Ward CW, Padilla IT, Cabrales E, Lopez JR, Eltit JM, Allen PD, Pessah IN. Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). Biochem Pharmacol. 2010 Aug 15; 80(4):512-21. PMID: 20471964; PMCID: PMC2907350.
    72. Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR. A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28. PMID: 20479110; PMCID: PMC2888056.
    73. Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG. A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40. PMID: 20479108; PMCID: PMC2888063.
    74. Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R. Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins. Neurotoxicology. 2010 Aug; 31(4):399-402. PMID: 20466021; PMCID: PMC3918243.
    75. Rose M, Bennett DH, Bergman A, Fängström B, Pessah IN, Hertz-Picciotto I. PBDEs in 2-5 year-old children from California and associations with diet and indoor environment. Environ Sci Technol. 2010 Apr 01; 44(7):2648-53. PMID: 20196589; PMCID: PMC3900494.
    76. Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR. RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem. 2010 Apr 30; 285(18):13781-7. PMID: 20207743; PMCID: PMC2859541.
    77. Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environ Health Perspect. 2010 Jan; 118(1):161-6. PMID: 20056569; PMCID: PMC2831962.
    78. Chen Y, Tassone F, Berman RF, Hagerman PJ, Hagerman RJ, Willemsen R, Pessah IN. Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Hum Mol Genet. 2010 Jan 01; 19(1):196-208. PMID: 19846466; PMCID: PMC2792156.
    79. Pessah IN, Cherednichenko G, Lein PJ. Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther. 2010 Feb; 125(2):260-85. PMID: 19931307; PMCID: PMC2823855.
    80. Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotox Res. 2011 Jan; 19(1):31-48. PMID: 19937285.
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    81. Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotox Res. 2011 Jan; 19(1):1-13. PMID: 19921347; PMCID: PMC3006638.
    82. Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect. 2009 Dec; 117(12):1867-72. PMID: 20049205; PMCID: PMC2799460.
    83. Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 2009 Sep; 30(5):811-21. PMID: 19596370; PMCID: PMC3014989.
    84. Barrientos G, Bose DD, Feng W, Padilla I, Pessah IN. The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Mol Pharmacol. 2009 Sep; 76(3):560-8. PMID: 19509218; PMCID: PMC2730388.
    85. Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7636-41. PMID: 19383796; PMCID: PMC2678594.
    86. Samsó M, Feng W, Pessah IN, Allen PD. Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol. 2009 Apr 14; 7(4):e85. PMID: 19402748; PMCID: PMC2672603.
    87. Kim KH, Inan SY, Berman RF, Pessah IN. Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation. Toxicol Appl Pharmacol. 2009 Jun 01; 237(2):168-77. PMID: 19289137; PMCID: PMC2693412.
    88. Ashwood P, Schauer J, Pessah IN, Van de Water J. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. J Neuroimmunol. 2009 Mar 31; 208(1-2):130-5. PMID: 19211157; PMCID: PMC2692510.
    89. Bannister RA, Pessah IN, Beam KG. The skeletal L-type Ca(2+) current is a major contributor to excitation-coupled Ca(2+) entry. J Gen Physiol. 2009 Jan; 133(1):79-91. PMID: 19114636; PMCID: PMC2606935.
    90. Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chem Res Toxicol. 2009 Jan; 22(1):201-7. PMID: 18954145; PMCID: PMC2662366.
    91. Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. Increased IgG4 levels in children with autism disorder. Brain Behav Immun. 2009 Mar; 23(3):389-95. PMID: 19136055; PMCID: PMC2696343.
    92. Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J Neuroimmunol. 2008 Nov 15; 204(1-2):149-53. PMID: 18762342; PMCID: PMC2615583.
    93. Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Res. 2008 Oct; 1(5):275-83. PMID: 19343198; PMCID: PMC2663897.
    94. Yang D, Kim KH, Phimister A, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PR, Anderson KA, Wayman G, Pessah IN, Lein PJ. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environ Health Perspect. 2009 Mar; 117(3):426-35. PMID: 19337518; PMCID: PMC2661913.
    95. Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect. 2008 Sep; 116(9):1203-10. PMID: 18795164; PMCID: PMC2535623.
    96. Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain Behav Immun. 2009 Jan; 23(1):124-33. PMID: 18762240; PMCID: PMC2636576.
    97. Vogel CF, Goth SR, Dong B, Pessah IN, Matsumura F. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun. 2008 Oct 24; 375(3):331-5. PMID: 18694728; PMCID: PMC2583959.
    98. Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008 Jun; 1(3):169-78. PMID: 19132145.
      View in: PubMed
    99. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. PMID: 18394707; PMCID: PMC2475601.
    100. Gach MP, Cherednichenko G, Haarmann C, Lopez JR, Beam KG, Pessah IN, Franzini-Armstrong C, Allen PD. Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes. Biophys J. 2008 Apr 15; 94(8):3023-34. PMID: 18192372; PMCID: PMC2275671.
    101. Cherednichenko G, Ward CW, Feng W, Cabrales E, Michaelson L, Samso M, López JR, Allen PD, Pessah IN. Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol. 2008 Apr; 73(4):1203-12. PMID: 18171728; PMCID: PMC2735873.
    102. Voss AA, Allen PD, Pessah IN, Perez CF. Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):988-93. PMID: 18096513; PMCID: PMC2693413.
    103. Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR. Gene expression changes in children with autism. Genomics. 2008 Jan; 91(1):22-9. PMID: 18006270.
      View in: PubMed
    104. Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: maternally derived antibodies specific for fetal brain proteins. Neurotoxicology. 2008 Mar; 29(2):226-31. PMID: 18078998; PMCID: PMC2305723.
    105. Berman RF, Pessah IN, Mouton PR, Mav D, Harry J. Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice. Toxicol Sci. 2008 Feb; 101(2):294-309. PMID: 17977901.
      View in: PubMed
    106. Yang T, Allen PD, Pessah IN, Lopez JR. Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. J Biol Chem. 2007 Dec 28; 282(52):37471-8. PMID: 17942409.
      View in: PubMed
    107. Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium. 2008 Mar; 43(3):307-14. PMID: 17707505; PMCID: PMC2288792.
    108. Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells. J Pharmacol Exp Ther. 2007 Oct; 323(1):381-90. PMID: 17640951.
      View in: PubMed
    109. Shahbazzadeh D, Srairi-Abid N, Feng W, Ram N, Borchani L, Ronjat M, Akbari A, Pessah IN, De Waard M, El Ayeb M. Hemicalcin, a new toxin from the Iranian scorpion Hemiscorpius lepturus which is active on ryanodine-sensitive Ca2+ channels. Biochem J. 2007 May 15; 404(1):89-96. PMID: 17291197; PMCID: PMC1868827.
    110. Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? J Autism Dev Disord. 2008 Jan; 38(1):169-75. PMID: 17347881.
      View in: PubMed
    111. Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007 Mar 23; 282(12):8667-77. PMID: 17237236.
      View in: PubMed
    112. Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. PMID: 17182726.
      View in: PubMed
    113. Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75. PMID: 17122579.
      View in: PubMed
    114. Ta TA, Pessah IN. Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). Neurotoxicology. 2007 Jul; 28(4):770-9. PMID: 17023049; PMCID: PMC2274001.
    115. Masuno MN, Pessah IN, Olmstead MM, Molinski TF. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. J Med Chem. 2006 Jul 27; 49(15):4497-511. PMID: 16854055; PMCID: PMC3987770.
    116. Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect. 2006 Jul; 114(7):1119-25. PMID: 16835068; PMCID: PMC1513329.
    117. Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environ Health Perspect. 2006 Jul; 114(7):1083-91. PMID: 16835063; PMCID: PMC1513334.
    118. Fessenden JD, Feng W, Pessah IN, Allen PD. Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem. 2006 Jul 28; 281(30):21022-31. PMID: 16737973.
      View in: PubMed
    119. Lee EH, Cherednichenko G, Pessah IN, Allen PD. Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J Biol Chem. 2006 Apr 14; 281(15):10042-8. PMID: 16484216.
      View in: PubMed
    120. Hansen ME, Pessah IN, Matsumura F. Heptachlor epoxide induces a non-capacitative type of Ca2+ entry and immediate early gene expression in mouse hepatoma cells. Toxicology. 2006 Mar 15; 220(2-3):218-31. PMID: 16469423.
      View in: PubMed
    121. Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chem Res Toxicol. 2006 Jan; 19(1):92-101. PMID: 16411661.
      View in: PubMed
    122. Goth SR, Chu RA, Pessah IN. Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression. J Immunol Methods. 2006 Jan 20; 308(1-2):179-91. PMID: 16406060.
      View in: PubMed
    123. Roegge CS, Morris JR, Villareal S, Wang VC, Powers BE, Klintsova AY, Greenough WT, Pessah IN, Schantz SL. Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicol Teratol. 2006 Jan-Feb; 28(1):74-85. PMID: 16309888.
      View in: PubMed
    124. Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB J. 2006 Feb; 20(2):329-30. PMID: 16284304.
      View in: PubMed
    125. Ta TA, Feng W, Molinski TF, Pessah IN. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors. Mol Pharmacol. 2006 Feb; 69(2):532-8. PMID: 16249374.
      View in: PubMed
    126. Dietrich KN, Eskenazi B, Schantz S, Yolton K, Rauh VA, Johnson CB, Alkon A, Canfield RL, Pessah IN, Berman RF. Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect. 2005 Oct; 113(10):1437-46. PMID: 16203260; PMCID: PMC1281293.
    127. Kostyniak PJ, Hansen LG, Widholm JJ, Fitzpatrick RD, Olson JR, Helferich JL, Kim KH, Sable HJ, Seegal RF, Pessah IN, Schantz SL. Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish. Toxicol Sci. 2005 Dec; 88(2):400-11. PMID: 16177234.
      View in: PubMed
    128. Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN. Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. J Biol Chem. 2005 Nov 04; 280(44):36994-7004. PMID: 16120606.
      View in: PubMed
    129. Gao J, Voss AA, Pessah IN, Lauer FT, Penning TM, Burchiel SW. Ryanodine receptor-mediated rapid increase in intracellular calcium induced by 7,8-benzo(a)pyrene quinone in human and murine leukocytes. Toxicol Sci. 2005 Oct; 87(2):419-26. PMID: 16049270.
      View in: PubMed
    130. Inceoglu B, Lango J, Pessah IN, Hammock BD. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon. 2005 May; 45(6):727-33. PMID: 15804521.
      View in: PubMed
    131. Cherednichenko G, Hurne AM, Fessenden JD, Lee EH, Allen PD, Beam KG, Pessah IN. Conformational activation of Ca2+ entry by depolarization of skeletal myotubes. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15793-8. PMID: 15505226; PMCID: PMC524834.
    132. Fessenden JD, Feng W, Pessah IN, Allen PD. Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. J Biol Chem. 2004 Dec 17; 279(51):53028-35. PMID: 15469935.
      View in: PubMed
    133. Aleman M, Riehl J, Aldridge BM, Lecouteur RA, Stott JL, Pessah IN. Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia. Muscle Nerve. 2004 Sep; 30(3):356-65. PMID: 15318347.
      View in: PubMed
    134. Paolini C, Fessenden JD, Pessah IN, Franzini-Armstrong C. Evidence for conformational coupling between two calcium channels. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12748-52. PMID: 15310845; PMCID: PMC515124.
    135. Voss AA, Lango J, Ernst-Russell M, Morin D, Pessah IN. Identification of hyperreactive cysteines within ryanodine receptor type 1 by mass spectrometry. J Biol Chem. 2004 Aug 13; 279(33):34514-20. PMID: 15197184.
      View in: PubMed
    136. Cherednichenko G, Zima AV, Feng W, Schaefer S, Blatter LA, Pessah IN. NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. Circ Res. 2004 Mar 05; 94(4):478-86. PMID: 14699012.
      View in: PubMed
    137. Ward CW, Feng W, Tu J, Pessah IN, Worley PK, Schneider MF. Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscle. J Biol Chem. 2004 Feb 13; 279(7):5781-7. PMID: 14660561.
      View in: PubMed
    138. Gafni J, Wong PW, Pessah IN. Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. Toxicol Sci. 2004 Jan; 77(1):72-82. PMID: 14600284.
      View in: PubMed
    139. Lee EH, Lopez JR, Li J, Protasi F, Pessah IN, Kim DH, Allen PD. Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C179-89. PMID: 13679303.
      View in: PubMed
    140. Estève E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M. Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. J Biol Chem. 2003 Sep 26; 278(39):37822-31. PMID: 12869557.
      View in: PubMed
    141. Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol Appl Pharmacol. 2003 Jul 01; 190(1):72-86. PMID: 12831785.
      View in: PubMed
    142. Fessenden JD, Perez CF, Goth S, Pessah IN, Allen PD. Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem. 2003 Aug 01; 278(31):28727-35. PMID: 12761215.
      View in: PubMed
    143. Yang T, Ta TA, Pessah IN, Allen PD. Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem. 2003 Jul 11; 278(28):25722-30. PMID: 12732639.
      View in: PubMed
    144. Perez CF, Voss A, Pessah IN, Allen PD. RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophys J. 2003 Apr; 84(4):2655-63. PMID: 12668474; PMCID: PMC1302832.
    145. Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN. Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106. PMID: 12586831.
      View in: PubMed
    146. Inceoglu B, Lango J, Jing J, Chen L, Doymaz F, Pessah IN, Hammock BD. One scorpion, two venoms: prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):922-7. PMID: 12552107; PMCID: PMC298702.
    147. Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN. Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem. 2002 Nov 22; 277(47):44722-30. PMID: 12223488.
      View in: PubMed
    148. Pessah IN, Kim KH, Feng W. Redox sensing properties of the ryanodine receptor complex. Front Biosci. 2002 May 01; 7:a72-9. PMID: 11991848.
      View in: PubMed
    149. O'Brien JJ, Feng W, Allen PD, Chen SR, Pessah IN, Beam KG. Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J. 2002 May; 82(5):2428-35. PMID: 11964231; PMCID: PMC1302033.
    150. Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski TF. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. J Nat Prod. 2002 Mar; 65(3):249-54. PMID: 11908959.
      View in: PubMed
    151. Feng W, Pessah IN. Detection of redox sensor of ryanodine receptor complexes. Methods Enzymol. 2002; 353:240-53. PMID: 12078499.
      View in: PubMed
    152. Pessah IN. Ryanodine receptor acts as a sensor for redox stress. Pest Manag Sci. 2001 Oct; 57(10):941-5. PMID: 11695187.
      View in: PubMed
    153. Pessah IN, Beltzner C, Burchiel SW, Sridhar G, Penning T, Feng W. A bioactive metabolite of benzo[a]pyrene, benzo[a]pyrene-7,8-dione, selectively alters microsomal Ca2+ transport and ryanodine receptor function. Mol Pharmacol. 2001 Mar; 59(3):506-13. PMID: 11179446.
      View in: PubMed
    154. Pessah IN, Feng W. Functional role of hyperreactive sulfhydryl moieties within the ryanodine receptor complex. Antioxid Redox Signal. 2000; 2(1):17-25. PMID: 11232595.
      View in: PubMed