Loading...

Isaac N Pessah

Title(s)Professor, SCHOOL OF VETERINARY MEDICINE
SchoolUniversity of California, Davis
Phone530-752-6696
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Ma L, Herren AW, Espinal G, Randol J, McLaughlin B, Martinez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. Composition of the Intranuclear Inclusions of Fragile X-associated Tremor/Ataxia Syndrome. Acta Neuropathol Commun. 2019 Sep 03; 7(1):143. PMID: 31481131.
      View in: PubMed
    2. Truong KM, Cherednichenko G, Pessah IN. Interactions of Dichlorodiphenyltrichloroethane (DDT) and Dichlorodiphenyldichloroethylene (DDE) With Skeletal Muscle Ryanodine Receptor Type 1. Toxicol Sci. 2019 Aug 01; 170(2):509-524. PMID: 31127943.
      View in: PubMed
    3. Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG. Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice. Environ Pollut. 2019 Oct; 253:708-721. PMID: 31336350.
      View in: PubMed
    4. Zheng J, Yu Y, Feng W, Li J, Liu J, Zhang C, Dong Y, Pessah IN, Cao Z. Influence of Nanomolar Deltamethrin on the Hallmarks of Primary Cultured Cortical Neuronal Network and the Role of Ryanodine Receptors. Environ Health Perspect. 2019 Jun; 127(6):67003. PMID: 31166131.
      View in: PubMed
    5. Pessah IN, Lein PJ, Seegal RF, Sagiv SK. Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta Neuropathol. 2019 Sep; 138(3):363-387. PMID: 30976975.
      View in: PubMed
    6. Sethi S, Morgan RK, Feng W, Lin Y, Li X, Luna C, Koch M, Bansal R, Duffel MW, Puschner B, Zoeller RT, Lehmler HJ, Pessah IN, Lein PJ. Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Activity at the Thyroid Hormone Receptor and Ryanodine Receptor. Environ Sci Technol. 2019 04 02; 53(7):3948-3958. PMID: 30821444.
      View in: PubMed
    7. Pessah IN, Truong K. Additional Safety Assessments Needed for Diamide Insecticides. Toxicol Sci. 2019 Mar 04. PMID: 30830166.
      View in: PubMed
    8. Truong KM, Pessah IN. Comparison of Chlorantraniliprole and Flubendiamide Activity Toward Wild-Type and Malignant Hyperthermia-Susceptible Ryanodine Receptors and Heat Stress Intolerance. Toxicol Sci. 2019 02 01; 167(2):509-523. PMID: 30329129.
      View in: PubMed
    9. Zheng J, Chen J, Zou X, Zhao F, Guo M, Wang H, Zhang T, Zhang C, Feng W, Pessah IN, Cao Z. Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology. 2019 01; 70:112-121. PMID: 30458186.
      View in: PubMed
    10. Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. Genes Brain Behav. 2019 01; 18(1):e12526. PMID: 30311737.
      View in: PubMed
    11. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 11; 126(11):117004. PMID: 30465702.
      View in: PubMed
    12. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 Jul 03; 52(13):7594. PMID: 29916692.
      View in: PubMed
    13. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 05 01; 52(9):5469-5478. PMID: 29617551.
      View in: PubMed
    14. Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int. 2018 Jun; 25(17):16508-16521. PMID: 29322390.
      View in: PubMed
    15. Feng W, Zheng J, Robin G, Dong Y, Ichikawa M, Inoue Y, Mori T, Nakano T, Pessah IN. Enantioselectivity of 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Atropisomers toward Ryanodine Receptors (RyRs) and Their Influences on Hippocampal Neuronal Networks. Environ Sci Technol. 2017 Dec 19; 51(24):14406-14416. PMID: 29131945.
      View in: PubMed
    16. Holland EB, Goldstone JV, Pessah IN, Whitehead A, Reid NM, Karchner SI, Hahn ME, Nacci DE, Clark BW, Stegeman JJ. Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison. Aquat Toxicol. 2017 Nov; 192:105-115. PMID: 28942070.
      View in: PubMed
    17. Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN. Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 07 15; 26(14):2649-2666. PMID: 28444183.
      View in: PubMed
    18. Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen HM, Cajka T, Pessah I, Wulff H, Gee SJ, Hammock BD. Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits. Chemistry. 2017 Jun 22; 23(35):8466-8472. PMID: 28411375.
      View in: PubMed
    19. Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Mol Pharmacol. 2017 07; 92(1):88-99. PMID: 28428226.
      View in: PubMed
    20. Zhang R, Pessah IN. Divergent Mechanisms Leading to Signaling Dysfunction in Embryonic Muscle by Bisphenol A and Tetrabromobisphenol A. Mol Pharmacol. 2017 04; 91(4):428-436. PMID: 28143888.
      View in: PubMed
    21. Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep. 2016 12 13; 17(11):3035-3048. PMID: 27974215.
      View in: PubMed
    22. Cao Z, Xu J, Hulsizer S, Cui Y, Dong Y, Pessah IN. Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures. Neurotoxicology. 2017 01; 58:11-22. PMID: 27984050.
      View in: PubMed
    23. Holland EB, Feng W, Zheng J, Dong Y, Li X, Lehmler HJ, Pessah IN. An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors. Toxicol Sci. 2017 01; 155(1):170-181. PMID: 27655348.
      View in: PubMed
    24. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. PMID: 27467073.
      View in: PubMed
    25. Ronjat M, Feng W, Dardevet L, Dong Y, Al Khoury S, Chatelain FC, Vialla V, Chahboun S, Lesage F, Darbon H, Pessah IN, De Waard M. In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):E2460-8. PMID: 27071086.
      View in: PubMed
    26. Ahn KC, Ranganathan A, Bever CS, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol. 2016 Apr 05; 50(7):3754-61. PMID: 26937944.
      View in: PubMed
    27. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. PMID: 25882826.
      View in: PubMed
    28. Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture. Mol Pharmacol. 2015 Apr; 87(4):595-605. PMID: 25583085.
      View in: PubMed
    29. Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics. 2015 Jan; 12(1):234-49. PMID: 25256961.
      View in: PubMed
    30. Fritsch EB, Stegeman JJ, Goldstone JV, Nacci DE, Champlin D, Jayaraman S, Connon RE, Pessah IN. Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA. Aquat Toxicol. 2015 Feb; 159:156-66. PMID: 25546006.
      View in: PubMed
    31. Berman RF, Buijsen RA, Usdin K, Pintado E, Kooy F, Pretto D, Pessah IN, Nelson DL, Zalewski Z, Charlet-Bergeurand N, Willemsen R, Hukema RK. Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome. J Neurodev Disord. 2014; 6(1):25. PMID: 25136376.
      View in: PubMed
    32. Altamirano F, Eltit JM, Robin G, Linares N, Ding X, Pessah IN, Allen PD, López JR. Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle. J Biol Chem. 2014 Jul 04; 289(27):19180-90. PMID: 24847052.
      View in: PubMed
    33. Cao Z, Cui Y, Nguyen HM, Jenkins DP, Wulff H, Pessah IN. Nanomolar bifenthrin alters synchronous Ca2+ oscillations and cortical neuron development independent of sodium channel activity. Mol Pharmacol. 2014 Apr; 85(4):630-9. PMID: 24482397.
      View in: PubMed
    34. Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicol Sci. 2014 Apr; 138(2):379-92. PMID: 24385416.
      View in: PubMed
    35. Pretto DI, Kumar M, Cao Z, Cunningham CL, Durbin-Johnson B, Qi L, Berman R, Noctor SC, Hagerman RJ, Pessah IN, Tassone F. Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome. Neurobiol Aging. 2014 May; 35(5):1189-97. PMID: 24332449.
      View in: PubMed
    36. Niknam Y, Feng W, Cherednichenko G, Dong Y, Joshi SN, Vyas SM, Lehmler HJ, Pessah IN. Structure-activity relationship of selected meta- and para-hydroxylated non-dioxin like polychlorinated biphenyls: from single RyR1 channels to muscle dysfunction. Toxicol Sci. 2013 Dec; 136(2):500-13. PMID: 24014653.
      View in: PubMed
    37. Vogel CF, Wu D, Goth SR, Baek J, Lollies A, Domhardt R, Grindel A, Pessah IN. Aryl hydrocarbon receptor signaling regulates NF-?B RelB activation during dendritic-cell differentiation. Immunol Cell Biol. 2013 Oct; 91(9):568-75. PMID: 23999131.
      View in: PubMed
    38. Braunschweig D, Krakowiak P, Duncanson P, Boyce R, Hansen RL, Ashwood P, Hertz-Picciotto I, Pessah IN, Van de Water J. Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Transl Psychiatry. 2013 Jul 09; 3:e277. PMID: 23838888.
      View in: PubMed
    39. Fritsch EB, Pessah IN. Structure-activity relationship of non-coplanar polychlorinated biphenyls toward skeletal muscle ryanodine receptors in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol. 2013 Sep 15; 140-141:204-12. PMID: 23827775.
      View in: PubMed
    40. Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biol Psychiatry. 2013 Aug 01; 74(3):204-11. PMID: 23623455.
      View in: PubMed
    41. Lin YP, Pessah IN, Puschner B. Simultaneous determination of polybrominated diphenyl ethers and polychlorinated biphenyls by gas chromatography-tandem mass spectrometry in human serum and plasma. Talanta. 2013 Sep 15; 113:41-8. PMID: 23708622.
      View in: PubMed
    42. Cao Z, Hulsizer S, Cui Y, Pretto DL, Kim KH, Hagerman PJ, Tassone F, Pessah IN. Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion. J Biol Chem. 2013 May 10; 288(19):13831-41. PMID: 23553633.
      View in: PubMed
    43. Girirajan S, Johnson RL, Tassone F, Balciuniene J, Katiyar N, Fox K, Baker C, Srikanth A, Yeoh KH, Khoo SJ, Nauth TB, Hansen R, Ritchie M, Hertz-Picciotto I, Eichler EE, Pessah IN, Selleck SB. Global increases in both common and rare copy number load associated with autism. Hum Mol Genet. 2013 Jul 15; 22(14):2870-80. PMID: 23535821.
      View in: PubMed
    44. Tassone F, Choudhary NS, Tassone F, Durbin-Johnson B, Hansen R, Hertz-Picciotto I, Pessah I. Identification of expanded alleles of the FMR1 Gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) study. J Autism Dev Disord. 2013 Mar; 43(3):530-9. PMID: 22767137.
      View in: PubMed
    45. Fritsch EB, Connon RE, Werner I, Davies RE, Beggel S, Feng W, Pessah IN. Triclosan impairs swimming behavior and alters expression of excitation-contraction coupling proteins in fathead minnow (Pimephales promelas). Environ Sci Technol. 2013 Feb 19; 47(4):2008-17. PMID: 23305567.
      View in: PubMed
    46. Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. FASEB J. 2013 Mar; 27(3):991-1000. PMID: 23159934.
      View in: PubMed
    47. Koenig CM, Lango J, Pessah IN, Berman RF. Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice. Neurotoxicol Teratol. 2012 Nov-Dec; 34(6):571-80. PMID: 23022914.
      View in: PubMed
    48. Kaplan ES, Cao Z, Hulsizer S, Tassone F, Berman RF, Hagerman PJ, Pessah IN. Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model. J Neurochem. 2012 Nov; 123(4):613-21. PMID: 22924671.
      View in: PubMed
    49. Mitchell MM, Woods R, Chi LH, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder. Environ Mol Mutagen. 2012 Oct; 53(8):589-98. PMID: 22930557.
      View in: PubMed
    50. Braunschweig D, Golub MS, Koenig CM, Qi L, Pessah IN, Van de Water J, Berman RF. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. J Neuroimmunol. 2012 Nov 15; 252(1-2):56-65. PMID: 22951357.
      View in: PubMed
    51. Feng W, Hwang HS, Kryshtal DO, Yang T, Padilla IT, Tiwary AK, Puschner B, Pessah IN, Knollmann BC. Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin. Mol Pharmacol. 2012 Nov; 82(5):993-1000. PMID: 22918967.
      View in: PubMed
    52. Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14158-63. PMID: 22891308.
      View in: PubMed
    53. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²? dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. PMID: 22889812.
      View in: PubMed
    54. Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. J Autism Dev Disord. 2012 Jul; 42(7):1435-45. PMID: 22012245.
      View in: PubMed
    55. Koenig CM, Walker CK, Qi L, Pessah IN, Berman RF. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice. PLoS One. 2012; 7(6):e38911. PMID: 22719983.
      View in: PubMed
    56. Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. Signaling defects in iPSC-derived fragile X premutation neurons. Hum Mol Genet. 2012 Sep 01; 21(17):3795-805. PMID: 22641815.
      View in: PubMed
    57. Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8. PMID: 22547813.
      View in: PubMed
    58. Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environ Health Perspect. 2012 Jul; 120(7):997-1002. PMID: 22534141.
      View in: PubMed
    59. Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environ Health Perspect. 2012 Jul; 120(7):1003-9. PMID: 22534176.
      View in: PubMed
    60. Shelton JF, Hertz-Picciotto I, Pessah IN. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environ Health Perspect. 2012 Jul; 120(7):944-51. PMID: 22534084.
      View in: PubMed
    61. Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 01; 21(13):2923-35. PMID: 22466801.
      View in: PubMed
    62. Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, LaSalle JM. Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Hum Mol Genet. 2012 Jun 01; 21(11):2399-411. PMID: 22343140.
      View in: PubMed
    63. Barrientos GC, Feng W, Truong K, Matthaei KI, Yang T, Allen PD, Lopez JR, Pessah IN. Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle. J Biol Chem. 2012 Jan 20; 287(4):2863-76. PMID: 22139840.
      View in: PubMed
    64. Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN. Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage. FASEB J. 2012 Mar; 26(3):1311-22. PMID: 22131268.
      View in: PubMed
    65. Magby JP, Neal AP, Atchison WD, Pessah IP, Shafer TJ. Channelopathies: summary of the hot topic keynotes session. Neurotoxicology. 2011 Oct; 32(5):661-5. PMID: 21756936.
      View in: PubMed
    66. Kim KH, Pessah IN. Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. Neurotoxicology. 2011 Dec; 32(6):981-5. PMID: 21571002.
      View in: PubMed
    67. Tassone F, Qi L, Zhang W, Hansen RL, Pessah IN, Hertz-Picciotto I. MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism Res. 2011 Aug; 4(4):250-61. PMID: 21538940.
      View in: PubMed
    68. Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51. PMID: 21482776.
      View in: PubMed
    69. Ta TA, Koenig CM, Golub MS, Pessah IN, Qi L, Aronov PA, Berman RF. Bioaccumulation and behavioral effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice. Neurotoxicol Teratol. 2011 May-Jun; 33(3):393-404. PMID: 21334437.
      View in: PubMed
    70. Hertz-Picciotto I, Bergman A, Fängström B, Rose M, Krakowiak P, Pessah I, Hansen R, Bennett DH. Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study. Environ Health. 2011 Jan 05; 10(1):1. PMID: 21205326.
      View in: PubMed
    71. Lein PJ, Barnhart CD, Pessah IN. Acute hippocampal slice preparation and hippocampal slice cultures. Methods Mol Biol. 2011; 758:115-34. PMID: 21815062.
      View in: PubMed
    72. Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN. Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Mol Pharmacol. 2011 Mar; 79(3):420-31. PMID: 21156754.
      View in: PubMed
    73. Giulivi C, Zhang YF, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz-Picciotto I, Tassone F, Pessah IN. Mitochondrial dysfunction in autism. JAMA. 2010 Dec 01; 304(21):2389-96. PMID: 21119085.
      View in: PubMed
    74. Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environ Health Perspect. 2011 Apr; 119(4):519-26. PMID: 21106467.
      View in: PubMed
    75. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J Neuroimmunol. 2011 Mar; 232(1-2):196-9. PMID: 21095018.
      View in: PubMed
    76. Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN. Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice. J Biol Chem. 2011 Jan 07; 286(1):99-113. PMID: 20978128.
      View in: PubMed
    77. Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 01; 20(1):64-79. PMID: 20935171.
      View in: PubMed
    78. Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62. PMID: 20926377.
      View in: PubMed
    79. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain Behav Immun. 2011 Jul; 25(5):840-9. PMID: 20833247.
      View in: PubMed
    80. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav Immun. 2011 Jan; 25(1):40-5. PMID: 20705131.
      View in: PubMed
    81. Feng W, Cherednichenko G, Ward CW, Padilla IT, Cabrales E, Lopez JR, Eltit JM, Allen PD, Pessah IN. Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). Biochem Pharmacol. 2010 Aug 15; 80(4):512-21. PMID: 20471964.
      View in: PubMed
    82. Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR. A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28. PMID: 20479110.
      View in: PubMed
    83. Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG. A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40. PMID: 20479108.
      View in: PubMed
    84. Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R. Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins. Neurotoxicology. 2010 Aug; 31(4):399-402. PMID: 20466021.
      View in: PubMed
    85. Rose M, Bennett DH, Bergman A, Fängström B, Pessah IN, Hertz-Picciotto I. PBDEs in 2-5 year-old children from California and associations with diet and indoor environment. Environ Sci Technol. 2010 Apr 01; 44(7):2648-53. PMID: 20196589.
      View in: PubMed
    86. Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR. RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem. 2010 Apr 30; 285(18):13781-7. PMID: 20207743.
      View in: PubMed
    87. Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environ Health Perspect. 2010 Jan; 118(1):161-6. PMID: 20056569.
      View in: PubMed
    88. Chen Y, Tassone F, Berman RF, Hagerman PJ, Hagerman RJ, Willemsen R, Pessah IN. Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Hum Mol Genet. 2010 Jan 01; 19(1):196-208. PMID: 19846466.
      View in: PubMed
    89. Pessah IN, Cherednichenko G, Lein PJ. Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther. 2010 Feb; 125(2):260-85. PMID: 19931307.
      View in: PubMed
    90. Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotox Res. 2011 Jan; 19(1):31-48. PMID: 19937285.
      View in: PubMed
    91. Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotox Res. 2011 Jan; 19(1):1-13. PMID: 19921347.
      View in: PubMed
    92. Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect. 2009 Dec; 117(12):1867-72. PMID: 20049205.
      View in: PubMed
    93. Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 2009 Sep; 30(5):811-21. PMID: 19596370.
      View in: PubMed
    94. Barrientos G, Bose DD, Feng W, Padilla I, Pessah IN. The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Mol Pharmacol. 2009 Sep; 76(3):560-8. PMID: 19509218.
      View in: PubMed
    95. Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7636-41. PMID: 19383796.
      View in: PubMed
    96. Samsó M, Feng W, Pessah IN, Allen PD. Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol. 2009 Apr 14; 7(4):e85. PMID: 19402748.
      View in: PubMed
    97. Kim KH, Inan SY, Berman RF, Pessah IN. Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation. Toxicol Appl Pharmacol. 2009 Jun 01; 237(2):168-77. PMID: 19289137.
      View in: PubMed
    98. Ashwood P, Schauer J, Pessah IN, Van de Water J. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. J Neuroimmunol. 2009 Mar 31; 208(1-2):130-5. PMID: 19211157.
      View in: PubMed
    99. Bannister RA, Pessah IN, Beam KG. The skeletal L-type Ca(2+) current is a major contributor to excitation-coupled Ca(2+) entry. J Gen Physiol. 2009 Jan; 133(1):79-91. PMID: 19114636.
      View in: PubMed
    100. Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chem Res Toxicol. 2009 Jan; 22(1):201-7. PMID: 18954145.
      View in: PubMed
    101. Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. Increased IgG4 levels in children with autism disorder. Brain Behav Immun. 2009 Mar; 23(3):389-95. PMID: 19136055.
      View in: PubMed
    102. Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J Neuroimmunol. 2008 Nov 15; 204(1-2):149-53. PMID: 18762342.
      View in: PubMed
    103. Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Res. 2008 Oct; 1(5):275-83. PMID: 19343198.
      View in: PubMed
    104. Yang D, Kim KH, Phimister A, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PR, Anderson KA, Wayman G, Pessah IN, Lein PJ. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environ Health Perspect. 2009 Mar; 117(3):426-35. PMID: 19337518.
      View in: PubMed
    105. Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect. 2008 Sep; 116(9):1203-10. PMID: 18795164.
      View in: PubMed
    106. Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain Behav Immun. 2009 Jan; 23(1):124-33. PMID: 18762240.
      View in: PubMed
    107. Vogel CF, Goth SR, Dong B, Pessah IN, Matsumura F. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun. 2008 Oct 24; 375(3):331-5. PMID: 18694728.
      View in: PubMed
    108. Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008 Jun; 1(3):169-78. PMID: 19132145.
      View in: PubMed
    109. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. PMID: 18394707.
      View in: PubMed
    110. Gach MP, Cherednichenko G, Haarmann C, Lopez JR, Beam KG, Pessah IN, Franzini-Armstrong C, Allen PD. Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes. Biophys J. 2008 Apr 15; 94(8):3023-34. PMID: 18192372.
      View in: PubMed
    111. Cherednichenko G, Ward CW, Feng W, Cabrales E, Michaelson L, Samso M, López JR, Allen PD, Pessah IN. Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol. 2008 Apr; 73(4):1203-12. PMID: 18171728.
      View in: PubMed
    112. Voss AA, Allen PD, Pessah IN, Perez CF. Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):988-93. PMID: 18096513.
      View in: PubMed
    113. Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR. Gene expression changes in children with autism. Genomics. 2008 Jan; 91(1):22-9. PMID: 18006270.
      View in: PubMed
    114. Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: maternally derived antibodies specific for fetal brain proteins. Neurotoxicology. 2008 Mar; 29(2):226-31. PMID: 18078998.
      View in: PubMed
    115. Berman RF, Pessah IN, Mouton PR, Mav D, Harry J. Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice. Toxicol Sci. 2008 Feb; 101(2):294-309. PMID: 17977901.
      View in: PubMed
    116. Yang T, Allen PD, Pessah IN, Lopez JR. Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. J Biol Chem. 2007 Dec 28; 282(52):37471-8. PMID: 17942409.
      View in: PubMed
    117. Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium. 2008 Mar; 43(3):307-14. PMID: 17707505.
      View in: PubMed
    118. Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells. J Pharmacol Exp Ther. 2007 Oct; 323(1):381-90. PMID: 17640951.
      View in: PubMed
    119. Shahbazzadeh D, Srairi-Abid N, Feng W, Ram N, Borchani L, Ronjat M, Akbari A, Pessah IN, De Waard M, El Ayeb M. Hemicalcin, a new toxin from the Iranian scorpion Hemiscorpius lepturus which is active on ryanodine-sensitive Ca2+ channels. Biochem J. 2007 May 15; 404(1):89-96. PMID: 17291197.
      View in: PubMed
    120. Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7646-51. PMID: 17460041.
      View in: PubMed
    121. Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? J Autism Dev Disord. 2008 Jan; 38(1):169-75. PMID: 17347881.
      View in: PubMed
    122. Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007 Mar 23; 282(12):8667-77. PMID: 17237236.
      View in: PubMed
    123. Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. PMID: 17182726.
      View in: PubMed
    124. Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75. PMID: 17122579.
      View in: PubMed
    125. Ta TA, Pessah IN. Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). Neurotoxicology. 2007 Jul; 28(4):770-9. PMID: 17023049.
      View in: PubMed
    126. Masuno MN, Pessah IN, Olmstead MM, Molinski TF. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. J Med Chem. 2006 Jul 27; 49(15):4497-511. PMID: 16854055.
      View in: PubMed
    127. Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect. 2006 Jul; 114(7):1119-25. PMID: 16835068.
      View in: PubMed
    128. Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environ Health Perspect. 2006 Jul; 114(7):1083-91. PMID: 16835063.
      View in: PubMed
    129. Fessenden JD, Feng W, Pessah IN, Allen PD. Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem. 2006 Jul 28; 281(30):21022-31. PMID: 16737973.
      View in: PubMed
    130. Lee EH, Cherednichenko G, Pessah IN, Allen PD. Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J Biol Chem. 2006 Apr 14; 281(15):10042-8. PMID: 16484216.
      View in: PubMed
    131. Hansen ME, Pessah IN, Matsumura F. Heptachlor epoxide induces a non-capacitative type of Ca2+ entry and immediate early gene expression in mouse hepatoma cells. Toxicology. 2006 Mar 15; 220(2-3):218-31. PMID: 16469423.
      View in: PubMed
    132. Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chem Res Toxicol. 2006 Jan; 19(1):92-101. PMID: 16411661.
      View in: PubMed
    133. Goth SR, Chu RA, Pessah IN. Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression. J Immunol Methods. 2006 Jan 20; 308(1-2):179-91. PMID: 16406060.
      View in: PubMed
    134. Roegge CS, Morris JR, Villareal S, Wang VC, Powers BE, Klintsova AY, Greenough WT, Pessah IN, Schantz SL. Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicol Teratol. 2006 Jan-Feb; 28(1):74-85. PMID: 16309888.
      View in: PubMed
    135. Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB J. 2006 Feb; 20(2):329-30. PMID: 16284304.
      View in: PubMed
    136. Ta TA, Feng W, Molinski TF, Pessah IN. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors. Mol Pharmacol. 2006 Feb; 69(2):532-8. PMID: 16249374.
      View in: PubMed
    137. Dietrich KN, Eskenazi B, Schantz S, Yolton K, Rauh VA, Johnson CB, Alkon A, Canfield RL, Pessah IN, Berman RF. Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect. 2005 Oct; 113(10):1437-46. PMID: 16203260.
      View in: PubMed
    138. Kostyniak PJ, Hansen LG, Widholm JJ, Fitzpatrick RD, Olson JR, Helferich JL, Kim KH, Sable HJ, Seegal RF, Pessah IN, Schantz SL. Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish. Toxicol Sci. 2005 Dec; 88(2):400-11. PMID: 16177234.
      View in: PubMed
    139. Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN. Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. J Biol Chem. 2005 Nov 04; 280(44):36994-7004. PMID: 16120606.
      View in: PubMed
    140. Gao J, Voss AA, Pessah IN, Lauer FT, Penning TM, Burchiel SW. Ryanodine receptor-mediated rapid increase in intracellular calcium induced by 7,8-benzo(a)pyrene quinone in human and murine leukocytes. Toxicol Sci. 2005 Oct; 87(2):419-26. PMID: 16049270.
      View in: PubMed
    141. Inceoglu B, Lango J, Pessah IN, Hammock BD. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon. 2005 May; 45(6):727-33. PMID: 15804521.
      View in: PubMed
    142. Buchanan MF, Carter WC, Cowgill LM, Hurley DJ, Lewis SJ, MacLeod JN, Melton TR, Moore JN, Pessah I, Roberson M, Robertson TP, Smith ML, Vandenplas ML. Using 3D animations to teach intracellular signal transduction mechanisms: taking the arrows out of cells. J Vet Med Educ. 2005; 32(1):72-8. PMID: 15834824.
      View in: PubMed
    143. López JR, Linares N, Pessah IN, Allen PD. Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C606-12. PMID: 15537710.
      View in: PubMed
    144. Cherednichenko G, Hurne AM, Fessenden JD, Lee EH, Allen PD, Beam KG, Pessah IN. Conformational activation of Ca2+ entry by depolarization of skeletal myotubes. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15793-8. PMID: 15505226.
      View in: PubMed
    145. Fessenden JD, Feng W, Pessah IN, Allen PD. Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. J Biol Chem. 2004 Dec 17; 279(51):53028-35. PMID: 15469935.
      View in: PubMed
    146. Aleman M, Riehl J, Aldridge BM, Lecouteur RA, Stott JL, Pessah IN. Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia. Muscle Nerve. 2004 Sep; 30(3):356-65. PMID: 15318347.
      View in: PubMed
    147. Paolini C, Fessenden JD, Pessah IN, Franzini-Armstrong C. Evidence for conformational coupling between two calcium channels. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12748-52. PMID: 15310845.
      View in: PubMed
    148. Voss AA, Lango J, Ernst-Russell M, Morin D, Pessah IN. Identification of hyperreactive cysteines within ryanodine receptor type 1 by mass spectrometry. J Biol Chem. 2004 Aug 13; 279(33):34514-20. PMID: 15197184.
      View in: PubMed
    149. Cherednichenko G, Zima AV, Feng W, Schaefer S, Blatter LA, Pessah IN. NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. Circ Res. 2004 Mar 05; 94(4):478-86. PMID: 14699012.
      View in: PubMed
    150. Ward CW, Feng W, Tu J, Pessah IN, Worley PK, Schneider MF. Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscle. J Biol Chem. 2004 Feb 13; 279(7):5781-7. PMID: 14660561.
      View in: PubMed
    151. Gafni J, Wong PW, Pessah IN. Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. Toxicol Sci. 2004 Jan; 77(1):72-82. PMID: 14600284.
      View in: PubMed
    152. Lee EH, Lopez JR, Li J, Protasi F, Pessah IN, Kim DH, Allen PD. Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C179-89. PMID: 13679303.
      View in: PubMed
    153. Estève E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M. Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. J Biol Chem. 2003 Sep 26; 278(39):37822-31. PMID: 12869557.
      View in: PubMed
    154. Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol Appl Pharmacol. 2003 Jul 01; 190(1):72-86. PMID: 12831785.
      View in: PubMed
    155. Fessenden JD, Perez CF, Goth S, Pessah IN, Allen PD. Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem. 2003 Aug 01; 278(31):28727-35. PMID: 12761215.
      View in: PubMed
    156. Yang T, Ta TA, Pessah IN, Allen PD. Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem. 2003 Jul 11; 278(28):25722-30. PMID: 12732639.
      View in: PubMed
    157. Perez CF, Voss A, Pessah IN, Allen PD. RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophys J. 2003 Apr; 84(4):2655-63. PMID: 12668474.
      View in: PubMed
    158. Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN. Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106. PMID: 12586831.
      View in: PubMed
    159. Inceoglu B, Lango J, Jing J, Chen L, Doymaz F, Pessah IN, Hammock BD. One scorpion, two venoms: prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):922-7. PMID: 12552107.
      View in: PubMed
    160. Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN. Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem. 2002 Nov 22; 277(47):44722-30. PMID: 12223488.
      View in: PubMed
    161. Pessah IN, Kim KH, Feng W. Redox sensing properties of the ryanodine receptor complex. Front Biosci. 2002 May 01; 7:a72-9. PMID: 11991848.
      View in: PubMed
    162. O'Brien JJ, Feng W, Allen PD, Chen SR, Pessah IN, Beam KG. Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J. 2002 May; 82(5):2428-35. PMID: 11964231.
      View in: PubMed
    163. Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski TF. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. J Nat Prod. 2002 Mar; 65(3):249-54. PMID: 11908959.
      View in: PubMed
    164. Feng W, Pessah IN. Detection of redox sensor of ryanodine receptor complexes. Methods Enzymol. 2002; 353:240-53. PMID: 12078499.
      View in: PubMed
    165. Ward CW, Protasi F, Castillo D, Wang Y, Chen SR, Pessah IN, Allen PD, Schneider MF. Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J. 2001 Dec; 81(6):3216-30. PMID: 11720987.
      View in: PubMed
    166. Pessah IN. Ryanodine receptor acts as a sensor for redox stress. Pest Manag Sci. 2001 Oct; 57(10):941-5. PMID: 11695187.
      View in: PubMed
    167. Haak LL, Song LS, Molinski TF, Pessah IN, Cheng H, Russell JT. Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors. J Neurosci. 2001 Jun 01; 21(11):3860-70. PMID: 11356874.
      View in: PubMed
    168. Pessah IN, Beltzner C, Burchiel SW, Sridhar G, Penning T, Feng W. A bioactive metabolite of benzo[a]pyrene, benzo[a]pyrene-7,8-dione, selectively alters microsomal Ca2+ transport and ryanodine receptor function. Mol Pharmacol. 2001 Mar; 59(3):506-13. PMID: 11179446.
      View in: PubMed
    169. Fessenden JD, Chen L, Wang Y, Paolini C, Franzini-Armstrong C, Allen PD, Pessah IN. Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2865-70. PMID: 11226332.
      View in: PubMed
    170. Wong PW, Garcia EF, Pessah IN. ortho-substituted PCB95 alters intracellular calcium signaling and causes cellular acidification in PC12 cells by an immunophilin-dependent mechanism. J Neurochem. 2001 Jan; 76(2):450-63. PMID: 11208908.
      View in: PubMed
    171. Feng W, Liu G, Allen PD, Pessah IN. Transmembrane redox sensor of ryanodine receptor complex. J Biol Chem. 2000 Nov 17; 275(46):35902-7. PMID: 10998414.
      View in: PubMed
    172. Vali S, Carlsen R, Pessah I, Gorin F. Role of the sarcoplasmic reticulum in regulating the activity-dependent expression of the glycogen phosphorylase gene in contractile skeletal muscle cells. J Cell Physiol. 2000 Nov; 185(2):184-99. PMID: 11025440.
      View in: PubMed
    173. Fessenden JD, Wang Y, Moore RA, Chen SR, Allen PD, Pessah IN. Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J. 2000 Nov; 79(5):2509-25. PMID: 11053126.
      View in: PubMed
    174. Kiselyov KI, Shin DM, Wang Y, Pessah IN, Allen PD, Muallem S. Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol Cell. 2000 Aug; 6(2):421-31. PMID: 10983988.
      View in: PubMed
    175. Wild JS, Giri SN, Moore R, Pessah IN. Characterization of [(3)H]ryanodine binding sites in mammalian lung. Arch Biochem Biophys. 2000 Jul 01; 379(1):109-18. PMID: 10864448.
      View in: PubMed
    176. González A, Kirsch WG, Shirokova N, Pizarro G, Brum G, Pessah IN, Stern MD, Cheng H, Ríos E. Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4380-5. PMID: 10759554.
      View in: PubMed
    177. Fajloun Z, Kharrat R, Chen L, Lecomte C, Di Luccio E, Bichet D, El Ayeb M, Rochat H, Allen PD, Pessah IN, De Waard M, Sabatier JM. Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett. 2000 Mar 10; 469(2-3):179-85. PMID: 10713267.
      View in: PubMed
    178. Pessah IN, Feng W. Functional role of hyperreactive sulfhydryl moieties within the ryanodine receptor complex. Antioxid Redox Signal. 2000; 2(1):17-25. PMID: 11232595.
      View in: PubMed
    179. Chen L, Molinski TF, Pessah IN. Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner. J Biol Chem. 1999 Nov 12; 274(46):32603-12. PMID: 10551814.
      View in: PubMed
    180. Feng W, Liu G, Xia R, Abramson JJ, Pessah IN. Site-selective modification of hyperreactive cysteines of ryanodine receptor complex by quinones. Mol Pharmacol. 1999 May; 55(5):821-31. PMID: 10220560.
      View in: PubMed
    181. Buck ED, Lachnit WG, Pessah IN. Mechanisms of delta-hexachlorocyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function. J Pharmacol Exp Ther. 1999 Apr; 289(1):477-85. PMID: 10087040.
      View in: PubMed
    182. Buck ED, Pessah IN. Mechanisms of delta-hexachlorocyclohexane toxicity: II. Evidence for Ca2+-dependent K+-selective ionophore activity. J Pharmacol Exp Ther. 1999 Apr; 289(1):486-93. PMID: 10087041.
      View in: PubMed
    183. Kiselyov K, Xu X, Mozhayeva G, Kuo T, Pessah I, Mignery G, Zhu X, Birnbaumer L, Muallem S. Functional interaction between InsP3 receptors and store-operated Htrp3 channels. Nature. 1998 Dec 03; 396(6710):478-82. PMID: 9853757.
      View in: PubMed
    184. Narasimhan K, Pessah IN, Linden DJ. Inositol-1,4,5-trisphosphate receptor-mediated Ca mobilization is not required for cerebellar long-term depression in reduced preparations. J Neurophysiol. 1998 Dec; 80(6):2963-74. PMID: 9862899.
      View in: PubMed
    185. Moore RA, Nguyen H, Galceran J, Pessah IN, Allen PD. A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol. 1998 Feb 23; 140(4):843-51. PMID: 9472036.
      View in: PubMed
    186. Fischer LJ, Seegal RF, Ganey PE, Pessah IN, Kodavanti PR. Symposium overview: toxicity of non-coplanar PCBs. Toxicol Sci. 1998 Jan; 41(1):49-61. PMID: 9520341.
      View in: PubMed
    187. Gafni J, Munsch JA, Lam TH, Catlin MC, Costa LG, Molinski TF, Pessah IN. Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron. 1997 Sep; 19(3):723-33. PMID: 9331361.
      View in: PubMed
    188. DiJulio DH, Watson EL, Pessah IN, Jacobson KL, Ott SM, Buck ED, Singh JC. Ryanodine receptor type III (Ry3R) identification in mouse parotid acini. Properties and modulation of [3H]ryanodine-binding sites. J Biol Chem. 1997 Jun 20; 272(25):15687-96. PMID: 9188460.
      View in: PubMed
    189. Wong PW, Brackney WR, Pessah IN. Ortho-substituted polychlorinated biphenyls alter microsomal calcium transport by direct interaction with ryanodine receptors of mammalian brain. J Biol Chem. 1997 Jun 13; 272(24):15145-53. PMID: 9182535.
      View in: PubMed
    190. Wong PW, Pessah IN. Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. Mol Pharmacol. 1997 May; 51(5):693-702. PMID: 9145907.
      View in: PubMed
    191. Buck ED, Nguyen HT, Pessah IN, Allen PD. Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function. J Biol Chem. 1997 Mar 14; 272(11):7360-7. PMID: 9054435.
      View in: PubMed
    192. Pessah IN, Molinski TF, Meloy TD, Wong P, Buck ED, Allen PD, Mohr FC, Mack MM. Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C601-14. PMID: 9124304.
      View in: PubMed
    193. Wong PW, Joy RM, Albertson TE, Schantz SL, Pessah IN. Ortho-substituted 2,2',3,5',6-pentachlorobiphenyl (PCB 95) alters rat hippocampal ryanodine receptors and neuroplasticity in vitro: evidence for altered hippocampal function. Neurotoxicology. 1997; 18(2):443-56. PMID: 9291493.
      View in: PubMed
    194. Schantz SL, Seo BW, Wong PW, Pessah IN. Long-term effects of developmental exposure to 2,2',3,5',6-pentachlorobiphenyl (PCB 95) on locomotor activity, spatial learning and memory and brain ryanodine binding. Neurotoxicology. 1997; 18(2):457-67. PMID: 9291494.
      View in: PubMed
    195. Franklin MA, Penn SG, Lebrilla CB, Lam TH, Pessah IN, Molinski TF. Bastadin 20 and bastadin O-sulfate esters from Ianthella basta: novel modulators of the Ry1R FKBP12 receptor complex. J Nat Prod. 1996 Dec; 59(12):1121-7. PMID: 8988595.
      View in: PubMed
    196. Pessah IN, Lynch C, Gronert GA. Complex pharmacology of malignant hyperthermia. Anesthesiology. 1996 Jun; 84(6):1275-9. PMID: 8669666.
      View in: PubMed
    197. Wong PW, Pessah IN. Ortho-substituted polychlorinated biphenyls alter calcium regulation by a ryanodine receptor-mediated mechanism: structural specificity toward skeletal- and cardiac-type microsomal calcium release channels. Mol Pharmacol. 1996 Apr; 49(4):740-51. PMID: 8609904.
      View in: PubMed
    198. Nakai J, Dirksen RT, Nguyen HT, Pessah IN, Beam KG, Allen PD. Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature. 1996 Mar 07; 380(6569):72-5. PMID: 8598910.
      View in: PubMed
    199. Mohr FC, Alojipan SV, Dunston SK, Pessah IN. The delta isomer of hexachlorocyclohexane induces rapid release of the myo-inositol-1,4,5-trisphosphate-sensitive Ca2+ store and blocks capacitative Ca2+ entry in rat basophilic leukemia cells. Mol Pharmacol. 1995 Sep; 48(3):512-22. PMID: 7565633.
      View in: PubMed
    200. Kim E, Giri SN, Pessah IN. Iron(II) is a modulator of ryanodine-sensitive calcium channels of cardiac muscle sarcoplasmic reticulum. Toxicol Appl Pharmacol. 1995 Jan; 130(1):57-66. PMID: 7530865.
      View in: PubMed
    201. Liu G, Pessah IN. Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls. J Biol Chem. 1994 Dec 30; 269(52):33028-34. PMID: 7806531.
      View in: PubMed
    202. Mack MM, Molinski TF, Buck ED, Pessah IN. Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J Biol Chem. 1994 Sep 16; 269(37):23236-49. PMID: 8083229.
      View in: PubMed
    203. Lachnit WG, Phillips M, Gayman KJ, Pessah IN. Ryanodine and dihydropyridine binding patterns and ryanodine receptor mRNA levels in myopathic hamster heart. Am J Physiol. 1994 Sep; 267(3 Pt 2):H1205-13. PMID: 8092287.
      View in: PubMed
    204. Kim E, Giri SN, Pessah IN. Antithetical actions of mitoxantrone and doxorubicin on ryanodine-sensitive Ca++ release channels of rat cardiac sarcoplasmic reticulum: evidence for a competitive mechanism. J Pharmacol Exp Ther. 1994 Mar; 268(3):1212-21. PMID: 8138934.
      View in: PubMed
    205. Liu G, Abramson JJ, Zable AC, Pessah IN. Direct evidence for the existence and functional role of hyperreactive sulfhydryls on the ryanodine receptor-triadin complex selectively labeled by the coumarin maleimide 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin. Mol Pharmacol. 1994 Feb; 45(2):189-200. PMID: 8114670.
      View in: PubMed
    206. Hershey PE, Pessah IN, Mohr FC. Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. II. Modulation of the receptor in permeabilized cells by the cytosolic compartment. Biochim Biophys Acta. 1993 Apr 08; 1147(1):115-24. PMID: 8385493.
      View in: PubMed
    207. Mohr FC, Hershey PE, Zimányi I, Pessah IN. Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. I. Multiple conformational states of the receptor in a microsomal preparation. Biochim Biophys Acta. 1993 Apr 08; 1147(1):105-14. PMID: 8385492.
      View in: PubMed
    208. Abramson JJ, Milne S, Buck E, Pessah IN. Porphyrin induced calcium release from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys. 1993 Mar; 301(2):396-403. PMID: 7681662.
      View in: PubMed
    209. Favero TG, Pessah IN, Klug GA. Prolonged exercise reduces Ca2+ release in rat skeletal muscle sarcoplasmic reticulum. Pflugers Arch. 1993 Feb; 422(5):472-5. PMID: 7682687.
      View in: PubMed
    210. Pessah IN, Nieberg PS, Wilson BW. Ryanodine induces maturation of embryonic acetylcholinesterase forms in cultured quail myotubes. Life Sci. 1993; 52(15):1279-85. PMID: 7681926.
      View in: PubMed
    211. Zimányi I, Buck E, Abramson JJ, Mack MM, Pessah IN. Ryanodine induces persistent inactivation of the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol. 1992 Dec; 42(6):1049-57. PMID: 1480132.
      View in: PubMed
    212. Buck E, Zimanyi I, Abramson JJ, Pessah IN. Ryanodine stabilizes multiple conformational states of the skeletal muscle calcium release channel. J Biol Chem. 1992 Nov 25; 267(33):23560-7. PMID: 1331089.
      View in: PubMed
    213. Mack WM, Zimányi I, Pessah IN. Discrimination of multiple binding sites for antagonists of the calcium release channel complex of skeletal and cardiac sarcoplasmic reticulum. J Pharmacol Exp Ther. 1992 Sep; 262(3):1028-37. PMID: 1382127.
      View in: PubMed
    214. Pessah IN, Mohr FC, Schiedt M, Joy RM. Stereoselective modulation of ryanodine-sensitive calcium channels by the delta isomer of hexachlorocyclohexane (delta-HCH). J Pharmacol Exp Ther. 1992 Aug; 262(2):661-9. PMID: 1380081.
      View in: PubMed
    215. Stuart J, Pessah IN, Favero TG, Abramson JJ. Photooxidation of skeletal muscle sarcoplasmic reticulum induces rapid calcium release. Arch Biochem Biophys. 1992 Feb 01; 292(2):512-21. PMID: 1531000.
      View in: PubMed
    216. Xiong H, Buck E, Stuart J, Pessah IN, Salama G, Abramson JJ. Rose bengal activates the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys. 1992 Feb 01; 292(2):522-8. PMID: 1309975.
      View in: PubMed
    217. Pessah IN. Calcium release channel of sarcoplasmic reticulum: an important target for doxorubicin-mediated cardiotoxicity. Adv Exp Med Biol. 1992; 311:409-10. PMID: 1326869.
      View in: PubMed
    218. Pessah IN, Schiedt MJ, Shalaby MA, Mack M, Giri SN. Etiology of sarcoplasmic reticulum calcium release channel lesions in doxorubicin-induced cardiomyopathy. Toxicology. 1992; 72(2):189-206. PMID: 1314436.
      View in: PubMed
    219. Zimanyi I, Pessah IN. Pharmacological characterization of the specific binding of [3H]ryanodine to rat brain microsomal membranes. Brain Res. 1991 Oct 11; 561(2):181-91. PMID: 1666327.
      View in: PubMed
    220. Pessah IN, Zimanyi I. Characterization of multiple [3H]ryanodine binding sites on the Ca2+ release channel of sarcoplasmic reticulum from skeletal and cardiac muscle: evidence for a sequential mechanism in ryanodine action. Mol Pharmacol. 1991 May; 39(5):679-89. PMID: 1851961.
      View in: PubMed
    221. Zimányi I, Pessah IN. Comparison of [3H]ryanodine receptors and Ca++ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum. J Pharmacol Exp Ther. 1991 Mar; 256(3):938-46. PMID: 1848635.
      View in: PubMed
    222. Pessah IN, Durie EL, Schiedt MJ, Zimanyi I. Anthraquinone-sensitized Ca2+ release channel from rat cardiac sarcoplasmic reticulum: possible receptor-mediated mechanism of doxorubicin cardiomyopathy. Mol Pharmacol. 1990 Apr; 37(4):503-14. PMID: 2157959.
      View in: PubMed
    223. Pessah IN, Schiedt MJ. Early over-expression of low-affinity [3H]ryanodine receptor sites in heavy sarcoplasmic reticulum fraction from dystrophic chicken pectoralis major. Biochim Biophys Acta. 1990 Mar 30; 1023(1):98-106. PMID: 2156566.
      View in: PubMed
    224. Zaidi NF, Lagenaur CF, Abramson JJ, Pessah I, Salama G. Reactive disulfides trigger Ca2+ release from sarcoplasmic reticulum via an oxidation reaction. J Biol Chem. 1989 Dec 25; 264(36):21725-36. PMID: 2532212.
      View in: PubMed
    225. Abramson JJ, Buck E, Salama G, Casida JE, Pessah IN. Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum. J Biol Chem. 1988 Dec 15; 263(35):18750-8. PMID: 3198599.
      View in: PubMed
    226. Graziano MJ, Pessah IN, Matsuzawa M, Casida JE. Partial characterization of specific cantharidin binding sites in mouse tissues. Mol Pharmacol. 1988 Jun; 33(6):706-12. PMID: 3380085.
      View in: PubMed
    227. Waterhouse AL, Pessah IN, Francini AO, Casida JE. Structural aspects of ryanodine action and selectivity. J Med Chem. 1987 Apr; 30(4):710-6. PMID: 2435905.
      View in: PubMed
    228. Pessah IN, Stambuk RA, Casida JE. Ca2+-activated ryanodine binding: mechanisms of sensitivity and intensity modulation by Mg2+, caffeine, and adenine nucleotides. Mol Pharmacol. 1987 Mar; 31(3):232-8. PMID: 2436032.
      View in: PubMed
    229. Pessah IN, Anderson KW, Casida JE. Solubilization and separation of Ca2+-ATPase from the Ca2+-ryanodine receptor complex. Biochem Biophys Res Commun. 1986 Aug 29; 139(1):235-43. PMID: 2945551.
      View in: PubMed
    230. Pessah IN, Francini AO, Scales DJ, Waterhouse AL, Casida JE. Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles. J Biol Chem. 1986 Jul 05; 261(19):8643-8. PMID: 3722165.
      View in: PubMed
    231. Pessah IN, Waterhouse AL, Casida JE. The calcium-ryanodine receptor complex of skeletal and cardiac muscle. Biochem Biophys Res Commun. 1985 Apr 16; 128(1):449-56. PMID: 3985981.
      View in: PubMed
    232. Aronstam RS, Eldefrawi AT, Pessah IN, Daly JW, Albuquerque EX, Eldefrawi ME. Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. J Biol Chem. 1981 Mar 25; 256(6):2843-50. PMID: 7204378.
      View in: PubMed
    233. Holohan PD, Pessah NI, Pessah IN, Ross CR. Reconstitution of N1-methylnicotinamide and p-aminohippuric acid transport in phospholipid vesicles with a protein fraction isolated from dog kidney membranes. Mol Pharmacol. 1979 Jul; 16(1):343-56. PMID: 39247.
      View in: PubMed