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Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis Resistance. Cancer Res Commun. 2023 12 12; 3(12):2518-2530.
Banerjee D, Boboila S, Okochi S, Angelastro JM, Kadenhe-Chiweshe AV, Lopez G, Califano A, Connolly EP, Greene LA, Yamashiro DJ. PMID: 38014922; PMCID: PMC10714915.
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PubMed Mentions: Translation:
Humans
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A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties. Cancer Lett. 2023 07 28; 567:216280.
Dreyer CA, VanderVorst K, Natwick D, Bell G, Sood P, Hernandez M, Angelastro JM, Collins SR, Carraway KL. PMID: 37336284; PMCID: PMC10582999.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Targeting Transcription Factors ATF5, CEBPB and CEBPD with Cell-Penetrating Peptides to Treat Brain and Other Cancers. Cells. 2023 02 11; 12(4).
Greene LA, Zhou Q, Siegelin MD, Angelastro JM. PMID: 36831248; PMCID: PMC9954556.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents. Cancers (Basel). 2021 May 20; 13(10).
Zhou Q, Sun X, Pasquier N, Jefferson P, Nguyen TTT, Siegelin MD, Angelastro JM, Greene LA. PMID: 34065488; PMCID: PMC8161188.
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PubMed Mentions:
9
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Repurposing FDA approved drugs inhibiting mitochondrial function for targeting glioma-stem like cells. Biomed Pharmacother. 2021 Jan; 133:111058.
Datta S, Sears T, Cortopassi G, Woolard K, Angelastro JM. PMID: 33378970; PMCID: PMC8092590.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells. Pharmaceuticals (Basel). 2020 Nov 24; 13(12).
Sandoval JA, Tomilov A, Datta S, Allen S, O'Donnell R, Sears T, Woolard K, Kovalskyy D, Angelastro JM, Cortopassi G. PMID: 33255358; PMCID: PMC7761300.
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PubMed Mentions:
1
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PRMT1 promotes neuroblastoma cell survival through ATF5. Oncogenesis. 2020 May 15; 9(5):50.
Hua ZY, Hansen JN, He M, Dai SK, Choi Y, Fulton MD, Lloyd SM, Szemes M, Sen J, Ding HF, Angelastro JM, Fei X, Li HP, Wu CR, Yang SY, Malik K, Bao X, George Zheng Y, Liu CM, Schor NF, Li ZJ, Li XG. PMID: 32415090; PMCID: PMC7229216.
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PubMed Mentions:
17
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Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD. Mol Cancer Res. 2020 02; 18(2):216-228.
Sun X, Jefferson P, Zhou Q, Angelastro JM, Greene LA. PMID: 31676720; PMCID: PMC7561279.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer. Mitochondrion. 2020 01; 50:19-24.
Allen SA, Datta S, Sandoval J, Tomilov A, Sears T, Woolard K, Angelastro JM, Cortopassi GA. PMID: 31654752.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Dominant-negative ATF5 rapidly depletes survivin in tumor cells. Cell Death Dis. 2019 09 24; 10(10):709.
Sun X, Angelastro JM, Merino D, Zhou Q, Siegelin MD, Greene LA. PMID: 31551409; PMCID: PMC6760124.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. Oncotarget. 2017 Oct 13; 8(48):84595-84609.
Sears TK, Angelastro JM. PMID: 29137451; PMCID: PMC5663623.
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PubMed Mentions:
22 Fields:
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Targeting ATF5 in Cancer. Trends Cancer. 2017 07; 3(7):471-474.
Angelastro JM. PMID: 28718401; PMCID: PMC5646417.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Expression and targeting of transcription factor ATF5 in dog gliomas. Vet Comp Oncol. 2018 Mar; 16(1):102-107.
York D, Sproul CD, Chikere N, Dickinson PJ, Angelastro JM. PMID: 28480569; PMCID: PMC5677578.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination. Oncogene. 2017 09 07; 36(36):5158-5167.
Wald JH, Hatakeyama J, Printsev I, Cuevas A, Fry WHD, Saldana MJ, VanderVorst K, Rowson-Hodel A, Angelastro JM, Sweeney C, Carraway KL. PMID: 28481871; PMCID: PMC5589482.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers. Clin Cancer Res. 2016 Sep 15; 22(18):4698-711.
Karpel-Massler G, Horst BA, Shu C, Chau L, Tsujiuchi T, Bruce JN, Canoll P, Greene LA, Angelastro JM, Siegelin MD. PMID: 27126996; PMCID: PMC5026557.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. Oncotarget. 2016 Mar 15; 7(11):12718-30.
Cates CC, Arias AD, Nakayama Wong LS, Lamé MW, Sidorov M, Cayanan G, Rowland DJ, Fung J, Karpel-Massler G, Siegelin MD, Greene LA, Angelastro JM. PMID: 26863637; PMCID: PMC4914317.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53. PLoS One. 2012; 7(8):e42504.
Napoli E, Ross-Inta C, Wong S, Hung C, Fujisawa Y, Sakaguchi D, Angelastro J, Omanska-Klusek A, Schoenfeld R, Giulivi C. PMID: 22900024; PMCID: PMC3416855.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Dev Neurobiol. 2012 Jun; 72(6):789-804.
Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA. PMID: 22095825; PMCID: PMC3857133.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas. Oncogene. 2012 Feb 09; 31(6):739-51.
Arias A, Lamé MW, Santarelli L, Hen R, Greene LA, Angelastro JM. PMID: 21725368; PMCID: PMC3277917.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 01; 20(1):64-79.
Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. PMID: 20935171; PMCID: PMC3000676.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Overexpression of CD133 promotes drug resistance in C6 glioma cells. Mol Cancer Res. 2010 Aug; 8(8):1105-15.
Angelastro JM, Lamé MW. PMID: 20663862; PMCID: PMC2923683.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells. Mol Cancer Res. 2009 Jun; 7(6):933-43.
Li G, Li W, Angelastro JM, Greene LA, Liu DX. PMID: 19531563; PMCID: PMC2880174.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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The transcription factor ATF5: role in neurodevelopment and neural tumors. J Neurochem. 2009 Jan; 108(1):11-22.
Greene LA, Lee HY, Angelastro JM. PMID: 19046351; PMCID: PMC2680418.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimals
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Organotypic distribution of stem cell markers in formalin-fixed brain harboring glioblastoma multiforme. J Neurooncol. 2007 Nov; 85(2):149-57.
Schrot RJ, Ma JH, Greco CM, Arias AD, Angelastro JM. PMID: 17516028.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines. Int J Cancer. 2007 May 01; 120(9):1883-90.
Monaco SE, Angelastro JM, Szabolcs M, Greene LA. PMID: 17266024.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5. Oncogene. 2006 Feb 09; 25(6):907-16.
Angelastro JM, Canoll PD, Kuo J, Weicker M, Costa A, Bruce JN, Greene LA. PMID: 16170340.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Chapter 21 Cultured PC12 Cells A Model for Neuronal Function, Differentiation, and Survival. . 2006 Jan 1; 1(Methods Enzymol.147B1987):171-176.
Teng TK, Angelastro AJ, Cunningham CM, Greene GL. .
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Publisher Site Mentions:
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You can't go home again: transcriptionally driven alteration of cell signaling by NGF. Neurochem Res. 2005 Oct; 30(10):1347-52.
Greene LA, Angelastro JM. PMID: 16341597.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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ATF5 regulates the proliferation and differentiation of oligodendrocytes. Mol Cell Neurosci. 2005 Jul; 29(3):372-80.
Mason JL, Angelastro JM, Ignatova TN, Kukekov VG, Lin G, Greene LA, Goldman JE. PMID: 15950153.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes. J Neurosci. 2005 Apr 13; 25(15):3889-99.
Angelastro JM, Mason JL, Ignatova TN, Kukekov VG, Stengren GB, Goldman JE, Greene LA. PMID: 15829641; PMCID: PMC6724921.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Analysis of gene expression changes in a cellular model of Parkinson disease. Neurobiol Dis. 2005 Feb; 18(1):54-74.
Ryu EJ, Angelastro JM, Greene LA. PMID: 15649696.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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RAIDD aggregation facilitates apoptotic death of PC12 cells and sympathetic neurons. Cell Death Differ. 2004 Jun; 11(6):618-30.
Jabado O, Wang Q, Rideout HJ, Yeasmin M, Guo KX, Vekrellis K, Papantonis S, Angelastro JM, Troy CM, Stefanis L. PMID: 14765136.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons. J Neurosci. 2003 Jun 01; 23(11):4590-600.
Angelastro JM, Ignatova TN, Kukekov VG, Steindler DA, Stengren GB, Mendelsohn C, Greene LA. PMID: 12805299; PMCID: PMC6740805.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci. 2002 Dec 15; 22(24):10690-8.
Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, Greene LA. PMID: 12486162; PMCID: PMC6758450.
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PubMed Mentions:
231 Fields:
Translation:
AnimalsCells
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The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth. J Neurosci. 2002 Oct 15; 22(20):8971-80.
Töröcsik B, Angelastro JM, Greene LA. PMID: 12388604; PMCID: PMC6757672.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Blue-white selection step enhances the yield of SAGE concatemers. Biotechniques. 2002 Mar; 32(3):484, 486.
Angelastro JM, Ryu EJ, Törõcsik B, Fiske BK, Greene LA. PMID: 11911650.
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PubMed Mentions:
2 Fields:
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Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. BMC Neurosci. 2002; 3:3.
Angelastro JM, Töröcsik B, Greene LA. PMID: 11922865; PMCID: PMC100322.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation. J Neurosci. 2001 Jul 15; 21(14):5007-16.
Troy CM, Rabacchi SA, Hohl JB, Angelastro JM, Greene LA, Shelanski ML. PMID: 11438576; PMCID: PMC6762825.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Characterization of a novel isoform of caspase-9 that inhibits apoptosis. J Biol Chem. 2001 Apr 13; 276(15):12190-200.
Angelastro JM, Moon NY, Liu DX, Yang AS, Greene LA, Franke TF. PMID: 11278518.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling. Proc Natl Acad Sci U S A. 2000 Sep 12; 97(19):10424-9.
Angelastro JM, Klimaschewski L, Tang S, Vitolo OV, Weissman TA, Donlin LT, Shelanski ML, Greene LA. PMID: 10984536; PMCID: PMC27040.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols. Nucleic Acids Res. 2000 Jun 15; 28(12):E62.
Angelastro JM, Klimaschewski LP, Vitolo OV. PMID: 10871385; PMCID: PMC102747.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine. J Neurochem. 1998 Feb; 70(2):540-9.
Angelastro JM, Ho CL, Frappier T, Liem RK, Greene LA. PMID: 9453548.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Tyrosine phosphorylation of extracellular signal-regulated protein kinase 4 in response to growth factors. J Neurochem. 1996 Mar; 66(3):1191-7.
Peng X, Angelastro JM, Greene LA. PMID: 8769883.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Phosphorylation states of actin filament adenine nucleotides in detergent-extracted neuronal cytoskeletal fractions. Biochem Biophys Res Commun. 1994 Jun 30; 201(3):1490-4.
Angelastro JM, Purich DL. PMID: 8024594.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Microtubule dynamics: bioenergetics and control. Adv Enzymol Relat Areas Mol Biol. 1994; 69:121-54.
Purich DL, Angelastro JM. PMID: 7817867.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors. J Biol Chem. 1993 Oct 05; 268(28):21410-5.
Volonté C, Angelastro JM, Greene LA. PMID: 8407983.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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2'-Deoxy-GTP in the microtubule cytoskeleton of neuronal cells cultured with nerve growth factor. J Biol Chem. 1992 Dec 25; 267(36):25685-9.
Angelastro JM, Purich DL. PMID: 1464585.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Adenine and guanine nucleotide content of Triton-extracted cytoskeletal fractions of nonmuscle cells. Anal Biochem. 1992 Jul; 204(1):47-52.
Angelastro JM, Purich DL. PMID: 1514695.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Evidence against impaired brain microtubule protein polymerization at high glucose concentrations or during diabetes mellitus. J Neurochem. 1991 Jun; 56(6):2087-93.
Eaker EY, Angelastro JM, Purich DL, Sninsky CA. PMID: 2027016.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Apparently irreversible GTP hydrolysis attends tubulin self-assembly. Eur J Biochem. 1990 Jul 31; 191(2):507-11.
Angelastro JM, Purich DL. PMID: 2384097.
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PubMed Mentions: Fields:
Translation:
Cells