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Alexey Tomilov

Title(s)Associate Scientist, SCHOOL OF VETERINARY MEDICINE
SchoolUniversity of California, Davis
Phone530-754-9341
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Allen SA, Datta S, Sandoval J, Tomilov A, Sears T, Woolard K, Angelastro JM, Cortopassi GA. Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer. Mitochondrion. 2019 Oct 22; 50:19-24. PMID: 31654752.
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    2. Tomilov A, Allen S, Hui CK, Bettaieb A, Cortopassi G. Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition. Pharmacol Res. 2018 11; 137:89-103. PMID: 30290222.
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    3. Allen SA, Tomilov A, Cortopassi GA. Small molecules bind human mTOR protein and inhibit mTORC1 specifically. Biochem Pharmacol. 2018 09; 155:298-304. PMID: 30028993.
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    4. Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metab. 2018 05 01; 27(5):1156. PMID: 29719228.
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    5. Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metab. 2017 Sep 05; 26(3):539-546.e5. PMID: 28877457.
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    6. Datta S, He G, Tomilov A, Sahdeo S, Denison MS, Cortopassi G. In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride. Environ Health Perspect. 2017 08 22; 125(8):087015. PMID: 28885978.
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    7. Scharadin TM, He W, Yiannakou Y, Tomilov AA, Saldana M, Cortopassi GA, Carraway KL, Coleman MA, Henderson PT. Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system. PLoS One. 2017; 12(6):e0177761. PMID: 28586369.
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    8. Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Török NJ, Jiang JX. Galectin-3 regulates inflammasome activation in cholestatic liver injury. FASEB J. 2016 12; 30(12):4202-4213. PMID: 27630169.
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    9. Datta S, Tomilov A, Cortopassi G. Identification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutations. Mitochondrion. 2016 09; 30:177-86. PMID: 27497748.
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    10. Hagopian K, Kim K, López-Dominguez JA, Tomilov AA, Cortopassi GA, Ramsey JJ. Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver. Biochem Biophys Rep. 2016 Sep; 7:273-286. PMID: 28133633.
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    11. Tomilov A, Tomilova N, Shan Y, Hagopian K, Bettaieb A, Kim K, Pelicci PG, Haj F, Ramsey J, Cortopassi G. p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria. J Biol Chem. 2016 Jun 10; 291(24):12575-85. PMID: 27059956.
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    12. Hagopian K, Tomilov AA, Kim K, Cortopassi GA, Ramsey JJ. Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins. PLoS One. 2015; 10(4):e0124204. PMID: 25880638.
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    13. Tomilov A, Bettaieb A, Kim K, Sahdeo S, Tomilova N, Lam A, Hagopian K, Connell M, Fong J, Rowland D, Griffey S, Ramsey J, Haj F, Cortopassi G. Shc depletion stimulates brown fat activity in vivo and in vitro. Aging Cell. 2014 Dec; 13(6):1049-58. PMID: 25257068.
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    14. Sahdeo S, Tomilov A, Komachi K, Iwahashi C, Datta S, Hughes O, Hagerman P, Cortopassi G. High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects. Mitochondrion. 2014 Jul; 17:116-25. PMID: 25034306.
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    15. Ramsey JJ, Tran D, Giorgio M, Griffey SM, Koehne A, Laing ST, Taylor SL, Kim K, Cortopassi GA, Lloyd KC, Hagopian K, Tomilov AA, Migliaccio E, Pelicci PG, McDonald RB. The influence of Shc proteins on life span in mice. J Gerontol A Biol Sci Med Sci. 2014 Oct; 69(10):1177-85. PMID: 24336818.
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    16. Chen L, Liu T, Tran A, Lu X, Tomilov AA, Davies V, Cortopassi G, Chiamvimonvat N, Bers DM, Votruba M, Knowlton AA. OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. J Am Heart Assoc. 2012 Oct; 1(5):e003012. PMID: 23316298.
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    17. Hagopian K, Tomilov AA, Tomilova N, Kim K, Taylor SL, Lam AK, Cortopassi GA, McDonald RB, Ramsey JJ. Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis. Metabolism. 2012 Dec; 61(12):1703-13. PMID: 22683097.
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    18. Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG. Hepatic Src homology phosphatase 2 regulates energy balance in mice. Endocrinology. 2012 Jul; 153(7):3158-69. PMID: 22619361.
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    19. Bandaranayake PC, Tomilov A, Tomilova NB, Ngo QA, Wickett N, dePamphilis CW, Yoder JI. The TvPirin gene is necessary for haustorium development in the parasitic plant Triphysaria versicolor. Plant Physiol. 2012 Feb; 158(2):1046-53. PMID: 22128136.
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    20. Tomilov AA, Ramsey JJ, Hagopian K, Giorgio M, Kim KM, Lam A, Migliaccio E, Lloyd KC, Berniakovich I, Prolla TA, Pelicci P, Cortopassi GA. The Shc locus regulates insulin signaling and adiposity in mammals. Aging Cell. 2011 Feb; 10(1):55-65. PMID: 21040401.
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    21. Bandaranayake PC, Filappova T, Tomilov A, Tomilova NB, Jamison-McClung D, Ngo Q, Inoue K, Yoder JI. A single-electron reducing quinone oxidoreductase is necessary to induce haustorium development in the root parasitic plant Triphysaria. Plant Cell. 2010 Apr; 22(4):1404-19. PMID: 20424175.
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    22. Tomilov AA, Bicocca V, Schoenfeld RA, Giorgio M, Migliaccio E, Ramsey JJ, Hagopian K, Pelicci PG, Cortopassi GA. Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice. J Biol Chem. 2010 Jan 08; 285(2):1153-65. PMID: 19892704.
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    23. Yoder JI, Gunathilake P, Wu B, Tomilova N, Tomilov AA. Engineering host resistance against parasitic weeds with RNA interference. Pest Manag Sci. 2009 May; 65(5):460-6. PMID: 19235710.
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    24. Tomilov AA, Tomilova NB, Wroblewski T, Michelmore R, Yoder JI. Trans-specific gene silencing between host and parasitic plants. Plant J. 2008 Nov; 56(3):389-97. PMID: 18643992.
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    25. Tomilov A, Tomilova N, Yoder JI. Agrobacterium tumefaciens and Agrobacterium rhizogenes transformed roots of the parasitic plant Triphysaria versicolor retain parasitic competence. Planta. 2007 Apr; 225(5):1059-71. PMID: 17053892.
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    26. Torres MJ, Tomilov AA, Tomilova N, Reagan RL, Yoder JI. Pscroph, a parasitic plant EST database enriched for parasite associated transcripts. BMC Plant Biol. 2005 Nov 16; 5:24. PMID: 16288663.
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    27. Tomilov AA, Tomilova NB, Abdallah I, Yoder JI. Localized hormone fluxes and early haustorium development in the hemiparasitic plant Triphysaria versicolor. Plant Physiol. 2005 Jul; 138(3):1469-80. PMID: 15965023.
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    28. Ogarkova OA, Tomilov AA, Tomilova NB, Tarasov VA. [Identification of the gene whose mutation leads to the appearance of recessive lethal germlings in Arabidopsis thaliana]. Ontogenez. 2005 May-Jun; 36(3):222-4. PMID: 15977805.
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    29. Ogarkova OA, Tomilov AA, Tomilova NB, Tarasov VA. [Identification of the gene whose mutation leads to hypocotyl tropism in Arabidopsis thaliana]. Genetika. 2005 Mar; 41(3):427-9. PMID: 15865300.
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    30. Ogarkova OA, Tomilov AA, Tomilova NB, Pogorelko GV, Tarasov VA. [Identification of the gene whose mutation leads to the morphological changes in the hypocotyl of Arabidopsis thaliana]. Genetika. 2005 Feb; 41(2):166-70. PMID: 15810605.
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    31. Ogarkova OA, Tomilov AA, Tomilova NB, Tarasov VA. [Saving insertional recessive lethal mutants of Arabidopsis thaliana]. Ontogenez. 2004 May-Jun; 35(3):220-8. PMID: 15334825.
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    32. Fursova OV, Pogorelko GV, Avsyuk AY, Tomilova NV, Tomilov AA, Tarasov VA, Ogarkova OA. Identification of the potential gene that controlling cotyledon development in Arabidopsis thaliana seedlings. Dokl Biol Sci. 2004 Mar-Apr; 395:161-2. PMID: 15255152.
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    33. Ryzhova NN, Goryunova SV, Tomilov AA, Kochieva EZ. Two types of rDNA internal transcribed spacers (ITSs) in the Capsicum genome. Dokl Biol Sci. 2002 Nov-Dec; 387:539-41. PMID: 12577633.
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    34. Tomilova NB, Tomilov AA, Ogarkova OA, Soldatova OP, Tarasov VA. [Hormone-dependent insertional Arabidopsis thaliana mutants with decreased viability and fertility]. Genetika. 2001 Sep; 37(9):1251-7. PMID: 11642128.
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    35. Ogarkova OA, Tomilova NB, Tomilov AA, Tarasov VA. [Creation of a collection of morphological insertional mutants of Arabidopsis thaliana]. Genetika. 2001 Aug; 37(8):1081-7. PMID: 11642108.
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    36. Tomilova NB, Tomilov AA, Ogarkova OA, Tarasov VA. [Identification of mutant gene responsible for cotyledons necrosis in developing seedlings of Arabidopsis thaliana]. Genetika. 2001 Apr; 37(4):494-503. PMID: 11421122.
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    37. Tomilov AA, Tomilova NB, Ogarkova OA, Tarasov VA. [Identification of a gene, included in control of root system development in Arabidopsis thaliana]. Genetika. 2001 Jan; 37(1):36-45. PMID: 11234423.
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    38. Tomilov AA, Tomilova NB, Ogarkova OA, Tarasov VA. [Insertional mutagenesis of Arabidopsis thaliana: increase of germinating seeds transformation efficiency after sonication]. Genetika. 1999 Sep; 35(9):1214-22. PMID: 10576057.
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