Xiaosong Jiang

Title(s)Associate Adjunct Professor, School of Veterinary Medicine
SchoolSchool of Veterinary Medicine
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    Galectin-3 in Primary biliary Cirrhosis
    NIH R03DK106467Jun 1, 2015 - May 31, 2018
    Role: Principal Investigator
    Galectin-3 in Liver Fibrosis
    NIH K01DK090121Mar 1, 2012 - Sep 30, 2017
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Macrophage Nrf2, an anti-inflammatory signal in hepatic ischemia/reperfusion injury. Cell Mol Immunol. 2023 05; 20(5):427-428. Jiang JX. PMID: 36600051; PMCID: PMC10203325.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity. Biomed Pharmacother. 2020 Dec; 132:110823. Hui C, Tomilov A, Garcia C, Jiang X, Fash DM, Khdour OM, Rosso C, Filippini G, Prato M, Graham J, Hecht S, Havel P, Cortopassi G. PMID: 33045613.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    3. Digoxin improves steatohepatitis with differential involvement of liver cell subsets in mice through inhibition of PKM2 transactivation. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G387-G397. Zhao P, Han SN, Arumugam S, Yousaf MN, Qin Y, Jiang JX, Torok NJ, Chen Y, Mankash MS, Liu J, Li J, Iwakiri Y, Ouyang X. PMID: 31411894; PMCID: PMC6842989.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    4. The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease. Free Radic Biol Med. 2018 02 01; 115:412-420. Matsumoto M, Zhang J, Zhang X, Liu J, Jiang JX, Yamaguchi K, Taruno A, Katsuyama M, Iwata K, Ibi M, Cui W, Matsuno K, Marunaka Y, Itoh Y, Torok NJ, Yabe-Nishimura C. PMID: 29274380; PMCID: PMC5969997.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    5. NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease. Sci Rep. 2017 04 06; 7:46144. Sasaki Y, Dehnad A, Fish S, Sato A, Jiang J, Tian J, Schröder K, Brandes R, Török NJ. PMID: 28383062; PMCID: PMC5382722.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    6. Galectin-3 regulates inflammasome activation in cholestatic liver injury. FASEB J. 2016 12; 30(12):4202-4213. Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Török NJ, Jiang JX. PMID: 27630169; PMCID: PMC5102125.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    7. The Aryl Hydrocarbon Receptor: A Key Bridging Molecule of External and Internal Chemical Signals. Environ Sci Technol. 2015 Aug 18; 49(16):9518-31. Tian J, Feng Y, Fu H, Xie HQ, Jiang JX, Zhao B. PMID: 26079192; PMCID: PMC4696777.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    8. Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation. Lab Invest. 2015 Oct; 95(10):1145-56. Serizawa N, Tian J, Fukada H, Baghy K, Scott F, Chen X, Kiss Z, Olson K, Hsu D, Liu FT, Török NJ, Zhao B, Jiang JX. PMID: 26146960; PMCID: PMC4586310.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    9. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. Gastroenterology. 2015 Aug; 149(2):468-80.e10. Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schröder K, Shah A, Brandes RP, Haj FG, Török NJ. PMID: 25888330; PMCID: PMC4516583.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    10. MLK3 as a regulator of disease progression in Non-alcoholic steatohepatitis. Liver Int. 2014 Sep; 34(8):1131-2. Jiang JX, Török NJ. PMID: 24690035; PMCID: PMC4392882.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    11. Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice. Hepatology. 2013 Oct; 58(4):1339-48. Jiang JX, Chen X, Fukada H, Serizawa N, Devaraj S, Török NJ. PMID: 23703665; PMCID: PMC3897213.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    12. Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatology. 2013 Feb; 57(2):555-65. Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Török NJ, Jiang JX, Havel PJ, Lönnerdal B, Kim K, Halsted CH. PMID: 22945834; PMCID: PMC3566330.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    13. Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFβ tumor suppressor signaling pathways. Mol Cancer Res. 2012 Jul; 10(7):979-91. Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, de vere White RW, Farnham PJ, Zern M. PMID: 22622027; PMCID: PMC4166560.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    14. Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo. Free Radic Biol Med. 2012 Jul 15; 53(2):289-96. Jiang JX, Chen X, Serizawa N, Szyndralewiez C, Page P, Schröder K, Brandes RP, Devaraj S, Török NJ. PMID: 22618020; PMCID: PMC3392471.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    15. Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 15; 302(4):G439-46. Jiang JX, Chen X, Hsu DK, Baghy K, Serizawa N, Scott F, Takada Y, Takada Y, Fukada H, Chen J, Devaraj S, Adamson R, Liu FT, Török NJ. PMID: 22159281; PMCID: PMC3287392.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    16. Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One. 2011; 6(11):e27740. Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M. PMID: 22140464; PMCID: PMC3225380.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    17. Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo. Gastroenterology. 2010 Oct; 139(4):1375-84. Jiang JX, Venugopal S, Serizawa N, Chen X, Scott F, Li Y, Adamson R, Devaraj S, Shah V, Gershwin ME, Friedman SL, Török NJ. PMID: 20685364; PMCID: PMC2949521.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    18. Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease. Obesity (Silver Spring). 2010 Dec; 18(12):2268-73. Medici V, Ali MR, Seo S, Aoki CA, Rossaro L, Kim K, Fuller WD, Vidovszky TJ, Smith W, Jiang JX, Maganti K, Havel PJ, Kamboj A, Ramsamooj R, Török NJ. PMID: 20448542; PMCID: PMC4820322.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G101-6. Venugopal SK, Jiang J, Kim TH, Li Y, Wang SS, Torok NJ, Wu J, Zern MA. PMID: 19892940; PMCID: PMC2806096.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    20. Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways. J Hepatol. 2009 Jul; 51(1):139-48. Jiang JX, Mikami K, Venugopal S, Li Y, Török NJ. PMID: 19457567; PMCID: PMC2765371.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    21. Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism. Hepatology. 2008 Nov; 48(5):1497-505. Jiang JX, Mikami K, Shah VH, Torok NJ. PMID: 18925608; PMCID: PMC2596754.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    22. Nonalcoholic steatohepatitis and the metabolic syndrome. Metab Syndr Relat Disord. 2008 Mar; 6(1):1-7. Jiang J, Torok N. PMID: 18370830.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    23. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology. 2006 Mar; 43(3):435-43. Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern MA, Torok NJ. PMID: 16496318.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansAnimalsCells
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