Janine M LaSalle

Title(s)Professor, Medical Microbiology and Immunology
SchoolSchool of Medicine
Address3428 Tupper Hall
CA 95616
Phone530-754-7598
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    Collapse Research 
    Collapse Research Activities and Funding
    Imprinted snoRNA loci and circadian entrainment
    NIH/NICHD R01HD098038Jan 15, 2019 - Dec 31, 2023
    Role: Principal Investigator
    Neuroimmune interactions in Rett syndrome
    NIH/NIAAA R01AA027075Sep 10, 2018 - Jun 30, 2023
    Role: Principal Investigator
    PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)
    NIH/NIEHS R01ES029213Jun 1, 2018 - May 31, 2023
    Role: Principal Investigator
    Methylomic and genomic impacts of organic pollutants in Dup15q syndrome
    NIH/NIEHS R56ES021707Jun 12, 2012 - Sep 29, 2018
    Role: Principal Investigator
    Methylomic and genomic impacts of organic pollutants in Dup15q syndrome
    NIH/NIEHS R01ES021707Jun 12, 2012 - Feb 28, 2017
    Role: Principal Investigator
    Noncoding RNAs at the heart of the Prader-Willi locus
    NIH/NINDS R56NS076263Aug 1, 2011 - Sep 24, 2018
    Role: Principal Investigator
    Noncoding RNAs at the heart of the Prader-Willi locus
    NIH/NINDS R01NS076263Aug 1, 2011 - Jul 31, 2016
    Role: Principal Investigator
    iCys Laser Scanning Cytometer for UC Davis Core
    NIH/NCRR S10RR024747Apr 18, 2008 - Apr 17, 2009
    Role: Principal Investigator
    Epigenetic Interaction of MECP2 and Organic Pollutants in Neurodevelopment
    NIH/NIEHS R01ES015171Sep 25, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Epigenetic Etiologies of Autism-Spectrum Disorders
    NIH/NICHD R01HD048799Aug 10, 2005 - May 30, 2011
    Role: Principal Investigator
    The Role of MeCP2 in Rett Syndrome
    NIH/NINDS R01NS081913Dec 1, 2001 - Jul 31, 2017
    Role: Principal Investigator
    The Role of MeCP2 in Rett Syndrome
    NIH/NICHD R01HD041462Dec 1, 2001 - May 31, 2013
    Role: Principal Investigator
    LSC ANALYSIS OF CELL CYCLE REGULATED CHROMOSOME DYNAMICS
    NIH/NCI R21CA078851Sep 30, 1998 - Aug 31, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons. bioRxiv. 2024 Mar 29. Fugon OJG, Sharifi O, Heath NG, Soto DC, Gomez JA, Yasui DH, Mendiola AJP, O'Geen H, Beitnere U, Tomkova M, Haghani V, Dillon G, Segal DJ, LaSalle J. PMID: 38586056; PMCID: PMC10996714.
      View in: PubMed   Mentions:
    2. Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence. Mol Psychiatry. 2023 Dec 05. Choudhary P, Monasso GS, Karhunen V, Ronkainen J, Mancano G, Howe CG, Niu Z, Zeng X, Guan W, Dou J, Feinberg JI, Mordaunt C, Pesce G, Baïz N, Alfano R, Martens DS, Wang C, Isaevska E, Keikkala E, Mustaniemi S, Thio CHL, Fraszczyk E, Tobi EW, Starling AP, Cosin-Tomas M, Urquiza J, Röder S, Hoang TT, Page C, Jima DD, House JS, Maguire RL, Ott R, Pawlow X, Sirignano L, Zillich L, Malmberg A, Rauschert S, Melton P, Gong T, Karlsson R, Fore R, Perng W, Laubach ZM, Czamara D, Sharp G, Breton CV, Schisterman E, Yeung E, Mumford SL, Fallin MD, LaSalle JM, Schmidt RJ, Bakulski KM, Annesi-Maesano I, Heude B, Nawrot TS, Plusquin M, Ghantous A, Herceg Z, Nisticò L, Vafeiadi M, Kogevinas M, Vääräsmäki M, Kajantie E, Snieder H, Corpeleijn E, Steegers-Theunissen RPM, Yang IV, Dabelea D, Fossati S, Zenclussen AC, Herberth G, Magnus M, Håberg SE, London SJ, Munthe-Kaas MC, Murphy SK, Hoyo C, Ziegler AG, Hummel S, Witt SH, Streit F, Frank J, Räikkönen K, Lahti J, Huang RC, Almqvist C, Hivert MF, Jaddoe VWV, Järvelin MR, Kantomaa M, Felix JF, Sebert S. PMID: 38052982.
      View in: PubMed   Mentions:    Fields:    
    3. Epigenomic signature of major congenital heart defects in newborns with Down syndrome. Hum Genomics. 2023 Oct 06; 17(1):92. Mouat JS, Li S, Myint SS, Laufer BI, Lupo PJ, Schraw JM, Woodhouse JP, de Smith AJ, LaSalle JM. PMID: 37803336; PMCID: PMC10559462.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. The role of intestine in metabolic dysregulation in murine Wilson disease. Hepatol Commun. 2023 10 01; 7(10). Sarode GV, Mazi TA, Neier K, Shibata NM, Jospin G, Harder NHO, Caceres A, Heffern MC, Sharma AK, More SK, Dave M, Schroeder SM, Wang L, LaSalle JM, Lutsenko S, Medici V. PMID: 37695076; PMCID: PMC10497250.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Epigenomic signature of major congenital heart defects in newborns with Down syndrome. medRxiv. 2023 May 05. Mouat JS, Li S, Myint SS, Laufer BI, Lupo PJ, Schraw JM, Woodhouse JP, de Smith AJ, LaSalle JM. PMID: 37205408; PMCID: PMC10187438.
      View in: PubMed   Mentions:
    6. Pregnant in a Pandemic: Mental Wellbeing and Associated Healthy Behaviors Among Pregnant People in California During COVID-19. Matern Child Health J. 2023 Jul; 27(7):1254-1263. Phipps JE, Whipps MDM, D'Souza I, LaSalle JM, Simmons LA. PMID: 37029891; PMCID: PMC10083068.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    7. Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder. Mol Psychiatry. 2023 05; 28(5):1890-1901. LaSalle JM. PMID: 36650278; PMCID: PMC10560404.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    8. The role of intestine in metabolic dysregulation in murine Wilson disease. bioRxiv. 2023 Jan 14. Sarode GV, Mazi TA, Neier K, Shibata NM, Jospin G, Harder NHO, Heffern MC, Sharma AK, More SK, Dave M, Schroeder SM, Wang L, LaSalle JM, Lutsenko S, Medici V. PMID: 36711483; PMCID: PMC9882126.
      View in: PubMed   Mentions:
    9. Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment. Environ Res. 2023 03 01; 220:115227. Mouat JS, Li X, Neier K, Zhu Y, Mordaunt CE, La Merrill MA, Lehmler HJ, Jones MP, Lein PJ, Schmidt RJ, LaSalle JM. PMID: 36608759; PMCID: PMC10518186.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    10. A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health. Commun Biol. 2022 11 30; 5(1):1313. Fernandez-Jimenez N, Fore R, Cilleros-Portet A, Lepeule J, Perron P, Kvist T, Tian FY, Lesseur C, Binder AM, Lozano M, Martorell-Marugán J, Loke YJ, Bakulski KM, Zhu Y, Forhan A, Sammallahti S, Everson TM, Chen J, Michels KB, Belmonte T, Carmona-Sáez P, Halliday J, Daniele Fallin M, LaSalle JM, Tost J, Czamara D, Fernández MF, Gómez-Martín A, Craig JM, Gonzalez-Alzaga B, Schmidt RJ, Dou JF, Muggli E, Lacasaña M, Vrijheid M, Marsit CJ, Karagas MR, Räikkönen K, Bouchard L, Heude B, Santa-Marina L, Bustamante M, Hivert MF, Bilbao JR. PMID: 36446949; PMCID: PMC9709064.
      View in: PubMed   Mentions: 3  Translation:HumansCells
    11. Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models. Nat Commun. 2022 09 21; 13(1):5538. Laufer BI, Hasegawa Y, Zhang Z, Hogrefe CE, Del Rosso LA, Haapanen L, Hwang H, Bauman MD, Van de Water J, Taha AY, Slupsky CM, Golub MS, Capitanio JP, VandeVoort CA, Walker CK, LaSalle JM. PMID: 36130949; PMCID: PMC9492781.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    12. Future Prospects for Epigenetics in Autism Spectrum Disorder. Mol Diagn Ther. 2022 Nov; 26(6):569-579. Williams LA, LaSalle JM. PMID: 35962910; PMCID: PMC9626414.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    13. Elevated exposures to persistent endocrine disrupting compounds impact the sperm methylome in regions associated with autism spectrum disorder. Front Genet. 2022; 13:929471. Maggio AG, Shu HT, Laufer BI, Bi C, Lai Y, LaSalle JM, Hu VW. PMID: 36035158; PMCID: PMC9403863.
      View in: PubMed   Mentions: 2  
    14. Prenatal vitamin intake in first month of pregnancy and DNA methylation in cord blood and placenta in two prospective cohorts. Epigenetics Chromatin. 2022 08 02; 15(1):28. Dou JF, Middleton LYM, Zhu Y, Benke KS, Feinberg JI, Croen LA, Hertz-Picciotto I, Newschaffer CJ, LaSalle JM, Fallin D, Schmidt RJ, Bakulski KM. PMID: 35918756; PMCID: PMC9344645.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. Comethyl: a network-based methylome approach to investigate the multivariate nature of health and disease. Brief Bioinform. 2022 03 10; 23(2). Mordaunt CE, Mouat JS, Schmidt RJ, LaSalle JM. PMID: 35037016; PMCID: PMC8921619.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. X Chromosome Inactivation Timing is Not eXACT: Implications for Autism Spectrum Disorders. Front Genet. 2022; 13:864848. LaSalle JM. PMID: 35356429; PMCID: PMC8959653.
      View in: PubMed   Mentions:
    17. Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure. Cell Rep. 2022 03 01; 38(9):110442. Laufer BI, Neier K, Valenzuela AE, Yasui DH, Schmidt RJ, Lein PJ, LaSalle JM. PMID: 35235788; PMCID: PMC8941983.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    18. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Genome Biol. 2022 02 16; 23(1):46. Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez Fugón OJ, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM. PMID: 35168652; PMCID: PMC8848662.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    19. The Promise of DNA Methylation in Understanding Multigenerational Factors in Autism Spectrum Disorders. Front Genet. 2022; 13:831221. Mouat JS, LaSalle JM. PMID: 35242170; PMCID: PMC8886225.
      View in: PubMed   Mentions: 4  
    20. Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome. Commun Biol. 2021 12 16; 4(1):1408. Neier K, Grant TE, Palmer RL, Chappell D, Hakam SM, Yasui KM, Rolston M, Settles ML, Hunter SS, Madany A, Ashwood P, Durbin-Johnson B, LaSalle JM, Yasui DH. PMID: 34916612; PMCID: PMC8677842.
      View in: PubMed   Mentions: 4  Translation:Animals
    21. Long-term effects of wildfire smoke exposure during early life on the nasal epigenome in rhesus macaques. Environ Int. 2022 01; 158:106993. Brown AP, Cai L, Laufer BI, Miller LA, LaSalle JM, Ji H. PMID: 34991254; PMCID: PMC8852822.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsPHPublic Health
    22. Placenta keeps the score of maternal cannabis use and child anxiety. Proc Natl Acad Sci U S A. 2021 11 23; 118(47). LaSalle JM. PMID: 34789581; PMCID: PMC8617424.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Exploring the evidence for epigenetic regulation of environmental influences on child health across generations. Commun Biol. 2021 06 22; 4(1):769. Breton CV, Landon R, Kahn LG, Enlow MB, Peterson AK, Bastain T, Braun J, Comstock SS, Duarte CS, Hipwell A, Ji H, LaSalle JM, Miller RL, Musci R, Posner J, Schmidt R, Suglia SF, Tung I, Weisenberger D, Zhu Y, Fry R. PMID: 34158610; PMCID: PMC8219763.
      View in: PubMed   Mentions: 37  Translation:HumansAnimalsCellsPHPublic Health
    24. Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1457-1477. Sarode GV, Neier K, Shibata NM, Shen Y, Goncharov DA, Goncharova EA, Mazi TA, Joshi N, Settles ML, LaSalle JM, Medici V. PMID: 34098115; PMCID: PMC8487080.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature. Epigenetics Chromatin. 2021 03 09; 14(1):13. Laufer BI, Gomez JA, Jianu JM, LaSalle JM. PMID: 33750431; PMCID: PMC7942011.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    26. Epigenetics in Prader-Willi Syndrome. Front Genet. 2021; 12:624581. Mendiola AJP, LaSalle JM. PMID: 33659026; PMCID: PMC7917289.
      View in: PubMed   Mentions: 8  
    27. Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles. Hum Mol Genet. 2021 01 06; 29(21):3465-3476. Laufer BI, Hwang H, Jianu JM, Mordaunt CE, Korf IF, Hertz-Picciotto I, LaSalle JM. PMID: 33001180; PMCID: PMC7788293.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    28. Expression Changes in Epigenetic Gene Pathways Associated With One-Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non-Typical Neurodevelopment. Autism Res. 2021 01; 14(1):11-28. Zhu Y, Mordaunt CE, Durbin-Johnson BP, Caudill MA, Malysheva OV, Miller JW, Green R, James SJ, Melnyk SB, Fallin MD, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. PMID: 33159718; PMCID: PMC7894157.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes. Genome Med. 2020 10 14; 12(1):88. Mordaunt CE, Jianu JM, Laufer BI, Zhu Y, Hwang H, Dunaway KW, Bakulski KM, Feinberg JI, Volk HE, Lyall K, Croen LA, Newschaffer CJ, Ozonoff S, Hertz-Picciotto I, Fallin MD, Schmidt RJ, LaSalle JM. PMID: 33054850; PMCID: PMC7559201.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    30. mtDNA depletion-like syndrome in Wilson disease. Liver Int. 2020 11; 40(11):2776-2787. Medici V, Sarode GV, Napoli E, Song GY, Shibata NM, Guimarães AO, Mordaunt CE, Kieffer DA, Mazi TA, Czlonkowska A, Litwin T, LaSalle JM, Giulivi C. PMID: 32996699; PMCID: PMC8079140.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    31. Publisher Correction: Integrated analysis of a compendium of RNA-Seq datasets for splicing factors. Sci Data. 2020 08 07; 7(1):267. Yu P, Li J, Deng SP, Zhang F, Grozdanov PN, Chin EWM, Martin SD, Vergnes L, Islam MS, Sun D, LaSalle JM, McGee SL, Goh E, MacDonald CC, Jin P. PMID: 32769981; PMCID: PMC7414123.
      View in: PubMed   Mentions:    Fields:    
    32. Integrated analysis of a compendium of RNA-Seq datasets for splicing factors. Sci Data. 2020 06 16; 7(1):178. Yu P, Li J, Deng SP, Zhang F, Grozdanov PN, Chin EWM, Martin SD, Vergnes L, Islam MS, Sun D, LaSalle JM, McGee SL, Goh E, MacDonald CC, Jin P. PMID: 32546682; PMCID: PMC7297722.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    33. Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages. Brain Behav Immun. 2020 10; 89:20-31. Ciernia AV, Link VM, Careaga M, LaSalle JM, Ashwood P. PMID: 32454135; PMCID: PMC7572655.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    34. Editorial: Secondary vs. Idiopathic Autism. Front Psychiatry. 2020; 11:297. Casanova MF, Casanova EL, Frye RE, Baeza-Velasco C, LaSalle JM, Hagerman RJ, Scherer SW, Natowicz MR. PMID: 32346372; PMCID: PMC7171716.
      View in: PubMed   Mentions: 11  
    35. A genome-wide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis. Hum Genet. 2020 Aug; 139(8):1077-1090. Justice CM, Cuellar A, Bala K, Sabourin JA, Cunningham ML, Crawford K, Phipps JM, Zhou Y, Cilliers D, Byren JC, Johnson D, Wall SA, Morton JEV, Noons P, Sweeney E, Weber A, Rees KEM, Wilson LC, Simeonov E, Kaneva R, Yaneva N, Georgiev K, Bussarsky A, Senders C, Zwienenberg M, Boggan J, Roscioli T, Tamburrini G, Barba M, Conway K, Sheffield VC, Brody L, Mills JL, Kay D, Sicko RJ, Langlois PH, Tittle RK, Botto LD, Jenkins MM, LaSalle JM, Lattanzi W, Wilkie AOM, Wilson AF, Romitti PA, Boyadjiev SA, National Birth Defects Prevention Study. PMID: 32266521; PMCID: PMC7415527.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    36. Imprinting effects of UBE3A loss on synaptic gene networks and Wnt signaling pathways. Hum Mol Genet. 2019 11 15; 28(22):3842-3852. Lopez SJ, Laufer BI, Beitnere U, Berg EL, Silverman JL, O'Geen H, Segal DJ, LaSalle JM. PMID: 31625566; PMCID: PMC7275372.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    37. A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood. Mol Autism. 2019; 10:36. Mordaunt CE, Park BY, Bakulski KM, Feinberg JI, Croen LA, Ladd-Acosta C, Newschaffer CJ, Volk HE, Ozonoff S, Hertz-Picciotto I, LaSalle JM, Schmidt RJ, Fallin MD. PMID: 31673306; PMCID: PMC6814108.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    38. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. Hum Mol Genet. 2019 08 15; 28(16):2659-2674. Zhu Y, Mordaunt CE, Yasui DH, Marathe R, Coulson RL, Dunaway KW, Jianu JM, Walker CK, Ozonoff S, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. PMID: 31009952; PMCID: PMC6687952.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCellsPHPublic Health
    39. Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights. Epigenetics. 2019 07; 14(7):672-684. Laufer BI, Hwang H, Vogel Ciernia A, Mordaunt CE, LaSalle JM. PMID: 31010359; PMCID: PMC6557615.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    40. Genetics and epigenetic factors of Wilson disease. Ann Transl Med. 2019 Apr; 7(Suppl 2):S58. Medici V, LaSalle JM. PMID: 31179295; PMCID: PMC6531661.
      View in: PubMed   Mentions: 19  
    41. Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers. Epigenetics Chromatin. 2019 02 01; 12(1):10. Mordaunt CE, Kieffer DA, Shibata NM, Czlonkowska A, Litwin T, Weiss KH, Zhu Y, Bowlus CL, Sarkar S, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. PMID: 30709419; PMCID: PMC6357467.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    42. UBE3A: An E3 Ubiquitin Ligase With Genome-Wide Impact in Neurodevelopmental Disease. Front Mol Neurosci. 2018; 11:476. Lopez SJ, Segal DJ, LaSalle JM. PMID: 30686997; PMCID: PMC6338038.
      View in: PubMed   Mentions: 19  
    43. MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome. Hum Mol Genet. 2018 12 01; 27(23):4077-4093. Vogel Ciernia A, Yasui DH, Pride MC, Durbin-Johnson B, Noronha AB, Chang A, Knotts TA, Rutkowsky JR, Ramsey JJ, Crawley JN, LaSalle JM. PMID: 30137367; PMCID: PMC6240741.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    44. Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN. Hum Mol Genet. 2018 12 01; 27(23):4051-4060. Coulson RL, Powell WT, Yasui DH, Dileep G, Resnick J, LaSalle JM. PMID: 30124848; PMCID: PMC6240740.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    45. Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease. Hum Mol Genet. 2018 11 15; 27(22):3854-3869. Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. PMID: 30010856; PMCID: PMC6216211.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 11; 126(11):117004. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. PMID: 30465702; PMCID: PMC6371714.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansPHPublic Health
    47. Cognitive deficits in the Snord116 deletion mouse model for Prader-Willi syndrome. Neurobiol Learn Mem. 2019 11; 165:106874. Adhikari A, Copping NA, Onaga B, Pride MC, Coulson RL, Yang M, Yasui DH, LaSalle JM, Silverman JL. PMID: 29800646; PMCID: PMC6520209.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    48. Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches. Epigenetics. 2018; 13(3):318-330. Vogel Ciernia A, Laufer BI, Dunaway KW, Mordaunt CE, Coulson RL, Totah TS, Stolzenberg DS, Frahm JC, Singh-Taylor A, Baram TZ, LaSalle JM, Yasui DH. PMID: 29613827; PMCID: PMC5997166.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    49. Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. Nat Commun. 2018 04 24; 9(1):1616. Coulson RL, Yasui DH, Dunaway KW, Laufer BI, Vogel Ciernia A, Zhu Y, Mordaunt CE, Totah TS, LaSalle JM. PMID: 29691382; PMCID: PMC5915486.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    50. Epigenetics of Circadian Rhythms in Imprinted Neurodevelopmental Disorders. Prog Mol Biol Transl Sci. 2018; 157:67-92. Coulson RL, LaSalle JM. PMID: 29933957.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    51. Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation. Epigenetics. 2018; 13(1):108-116. Dou J, Schmidt RJ, Benke KS, Newschaffer C, Hertz-Picciotto I, Croen LA, Iosif AM, LaSalle JM, Fallin MD, Bakulski KM. PMID: 29451060; PMCID: PMC5836975.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    52. Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism. Glia. 2018 03; 66(3):505-521. Vogel Ciernia A, Careaga M, LaSalle JM, Ashwood P. PMID: 29134693; PMCID: PMC5767155.
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    71. Corrigendum: Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis. Frontiers in Immunology. 2014 Aug 14; 5:371. Selmi SC, Cavaciocchi CF, Lleo LA, Cheroni CC, De Francesco DR, Lombardi LS, De Santis DM, Meda MF, Raimondo RM, Crotti CC, Folci FM, Zammataro ZL, Mayo MM, Bach BN, Shimoda SS, Gordon GS, Miozzo MM, Invernizzi IP, Podda PM, Scavelli SR, Martin MM, Seldin SM, LaSalle LJ, Gershwin GM. .
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    122. Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15. BMC Genet. 2008 Jan 04; 9:2. Wang NJ, Parokonny AS, Thatcher KN, Driscoll J, Malone BM, Dorrani N, Sigman M, LaSalle JM, Schanen NC. PMID: 18177502; PMCID: PMC2249594.
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    123. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc Natl Acad Sci U S A. 2007 Dec 04; 104(49):19416-21. Yasui DH, Peddada S, Bieda MC, Vallero RO, Hogart A, Nagarajan RP, Thatcher KN, Farnham PJ, Lasalle JM. PMID: 18042715; PMCID: PMC2148304.
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    124. 15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders. Hum Mol Genet. 2007 Mar 15; 16(6):691-703. Hogart A, Nagarajan RP, Patzel KA, Yasui DH, Lasalle JM. PMID: 17339270; PMCID: PMC1934608.
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    125. The odyssey of MeCP2 and parental imprinting. Epigenetics. 2007 Jan-Mar; 2(1):5-10. LaSalle JM. PMID: 17486180.
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    126. The Odyssey of MeCP2 and parental imprinting. Epigenetics. 2007 Jan-Mar; 2(1):5-10. LaSalle JM. PMID: 17965611; PMCID: PMC1866173.
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    127. Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics. 2006 Oct-Dec; 1(4):e1-11. Nagarajan RP, Hogart AR, Gwye Y, Martin MR, LaSalle JM. PMID: 17486179; PMCID: PMC1866172.
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    128. Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients. BMC Med Genet. 2006 Jul 21; 7:61. Delgado IJ, Kim DS, Thatcher KN, LaSalle JM, Van den Veyver IB. PMID: 16859563; PMCID: PMC1569822.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    129. Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome. Hum Mol Genet. 2006 Jun 15; 15(12):2003-14. Peddada S, Yasui DH, LaSalle JM. PMID: 16682435; PMCID: PMC1931415.
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    130. Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2. Epigenetics. 2006 Jan-Mar; 1(1):24-31. Thatcher KN, LaSalle JM. PMID: 17464364; PMCID: PMC1857283.
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    131. Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples. Hum Mol Genet. 2005 Mar 15; 14(6):785-97. Thatcher KN, Peddada S, Yasui DH, Lasalle JM. PMID: 15689352.
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    132. Rett syndrome: a Rosetta stone for understanding the molecular pathogenesis of autism. Int Rev Neurobiol. 2005; 71:131-65. LaSalle JM, Hogart A, Thatcher KN. PMID: 16512349.
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    133. Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum Mol Genet. 2005 Feb 15; 14(4):483-92. Samaco RC, Hogart A, LaSalle JM. PMID: 15615769; PMCID: PMC1224722.
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    134. X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain. Hum Mol Genet. 2004 Jun 15; 13(12):1275-86. Braunschweig D, Simcox T, Samaco RC, LaSalle JM. PMID: 15115765.
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    135. Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders. Hum Mol Genet. 2004 Mar 15; 13(6):629-39. Samaco RC, Nagarajan RP, Braunschweig D, LaSalle JM. PMID: 14734626.
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    136. Paradoxical role of methyl-CpG-binding protein 2 in Rett syndrome. Curr Top Dev Biol. 2004; 59:61-86. LaSalle JM. PMID: 14975247.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    137. Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation. J Mol Med (Berl). 2003 Jan; 81(1):61-8. Balmer D, Goldstine J, Rao YM, LaSalle JM. PMID: 12545250.
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    138. Does HER2/neu expression provide prognostic information in patients with advanced urothelial carcinoma? Cancer. 2002 Sep 01; 95(5):1009-15. Gandour-Edwards R, Lara PN, Folkins AK, LaSalle JM, Beckett L, Li Y, Meyers FJ, DeVere-White R. PMID: 12209684.
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    139. MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain. Hum Genet. 2002 Jun; 110(6):545-52. Balmer D, Arredondo J, Samaco RC, LaSalle JM. PMID: 12107440.
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    140. Detection of low level HER-2/neu gene amplification in prostate cancer by fluorescence in situ hybridization. Cancer J. 2001 Sep-Oct; 7(5):395-403. Liu HL, Gandour-Edwards R, Lara PN, de Vere White R, LaSalle JM. PMID: 11693898.
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    141. Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry. Hum Mol Genet. 2001 Aug 15; 10(17):1729-40. LaSalle JM, Goldstine J, Balmer D, Greco CM. PMID: 11532982.
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    142. Automated quantitation of cell-mediated HIV type 1 infection of human syncytiotrophoblast cells by fluorescence in situ hybridization and laser scanning cytometry. AIDS Res Hum Retroviruses. 2001 Apr 10; 17(6):507-16. Douglas GC, Thirkill TL, LaSalle J. PMID: 11350664.
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    143. Clonal maintenance of imprinted expression of SNRPN and IPW in normal lymphocytes: correlation with allele-specific methylation of SNRPN intron 1 but not intron 7. Hum Genet. 2001 Feb; 108(2):116-22. Balmer D, LaSalle JM. PMID: 11281449.
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    144. Flow cytometry and FISH to investigate allele-specific replication timing and homologous association of imprinted chromosomes. Methods Mol Biol. 2001; 181:181-92. LaSalle J, Lalande M. PMID: 12843450.
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    145. Clonal heterogeneity at allelic methylation sites diagnostic for Prader-Willi and Angelman syndromes. Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4):1675-80. LaSalle JM, Ritchie RJ, Glatt H, Lalande M. PMID: 9465075; PMCID: PMC19144.
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    146. High-resolution analysis of DNA replication domain organization across an R/G-band boundary. Mol Cell Biol. 1997 Oct; 17(10):6157-66. Strehl S, LaSalle JM, Lalande M. PMID: 9315676; PMCID: PMC232466.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    147. RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6927-32. Mizuta R, LaSalle JM, Cheng HL, Shinohara A, Ogawa H, Copeland N, Jenkins NA, Lalande M, Alt FW. PMID: 9192668; PMCID: PMC21261.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    148. Homologous association of oppositely imprinted chromosomal domains. Science. 1996 May 03; 272(5262):725-8. LaSalle JM, Lalande M. PMID: 8614834.
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    149. Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution. Nat Genet. 1995 Apr; 9(4):386-94. LaSalle JM, Lalande M. PMID: 7795644.
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    150. T cell anergy. FASEB J. 1994 Jun; 8(9):601-8. LaSalle JM, Hafler DA. PMID: 8005388.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    151. T-cell presentation of antigen requires cell-to-cell contact for proliferation and anergy induction. Differential MHC requirements for superantigen and autoantigen. J Immunol. 1993 Jul 15; 151(2):649-57. LaSalle JM, Toneguzzo F, Saadeh M, Golan DE, Taber R, Hafler DA. PMID: 7687620.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    152. Biological activity of recombinant human myelin basic protein. J Neuroimmunol. 1993 May; 44(2):157-62. Oettinger HF, al-Sabbagh A, Jingwu Z, LaSalle JM, Weiner HL, Hafler DA. PMID: 7685037.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    153. The development of antigen specific therapies for autoimmune diseases; investigations in multiple sclerosis as a paradigm for rheumatoid arthritis. Clin Exp Rheumatol. 1993 Mar-Apr; 11 Suppl 8:S39-40. Hafler DA, Zhang JW, LaSalle J, Donnelly C, Weiner HL, Wucherpfeffnig K. PMID: 7686832.
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    154. Early signaling defects in human T cells anergized by T cell presentation of autoantigen. J Exp Med. 1992 Jul 01; 176(1):177-86. LaSalle JM, Tolentino PJ, Freeman GJ, Nadler LM, Hafler DA. PMID: 1535366; PMCID: PMC2119294.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    155. The coexpression of CD45RA and CD45RO isoforms on T cells during the S/G2/M stages of cell cycle. Cell Immunol. 1991 Nov; 138(1):197-206. LaSalle JM, Hafler DA. PMID: 1833074.
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    156. Presentation of autoantigen by human T cells. J Immunol. 1991 Aug 01; 147(3):774-80. LaSalle JM, Ota K, Hafler DA. PMID: 1713605.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
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