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Janine M LaSalle

TitleProfessor
InstitutionUniversity of California Davis
DepartmentMedical Microbiology and Immunology
Address3428 Tupper Hall
CA 95616
Phone530-754-7598
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)
    NIH/NIEHS R01ES029213Jun 1, 2018 - May 31, 2023
    Role: Principal Investigator
    Methylomic and genomic impacts of organic pollutants in Dup15q syndrome
    NIH/NIEHS R56ES021707Jun 12, 2012 - Sep 29, 2018
    Role: Principal Investigator
    Methylomic and genomic impacts of organic pollutants in Dup15q syndrome
    NIH/NIEHS R01ES021707Jun 12, 2012 - Feb 28, 2017
    Role: Principal Investigator
    Noncoding RNAs at the heart of the Prader-Willi locus
    NIH/NINDS R56NS076263Aug 1, 2011 - Sep 24, 2018
    Role: Principal Investigator
    Noncoding RNAs at the heart of the Prader-Willi locus
    NIH/NINDS R01NS076263Aug 1, 2011 - Jul 31, 2016
    Role: Principal Investigator
    iCys Laser Scanning Cytometer for UC Davis Core
    NIH/NCRR S10RR024747Apr 18, 2008 - Apr 17, 2009
    Role: Principal Investigator
    Epigenetic Interaction of MECP2 and Organic Pollutants in Neurodevelopment
    NIH/NIEHS R01ES015171Sep 25, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Epigenetic Etiologies of Autism-Spectrum Disorders
    NIH/NICHD R01HD048799Aug 10, 2005 - May 30, 2011
    Role: Principal Investigator
    The Role of MeCP2 in Rett Syndrome
    NIH/NINDS R01NS081913Dec 1, 2001 - Jul 31, 2017
    Role: Principal Investigator
    The Role of MeCP2 in Rett Syndrome
    NIH/NICHD R01HD041462Dec 1, 2001 - May 31, 2013
    Role: Principal Investigator
    LSC ANALYSIS OF CELL CYCLE REGULATED CHROMOSOME DYNAMICS
    NIH/NCI R21CA078851Sep 30, 1998 - Aug 31, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 Nov; 126(11):117004. PMID: 30465702.
      View in: PubMed
    2. Ciernia AV, Yasui DH, Pride MC, Durbin-Johnson B, Noronha A, Chang A, Knotts T, Rutkowsky J, Ramsey JJ, Crawley JN, LaSalle JM. MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome. Hum Mol Genet. 2018 Aug 21. PMID: 30137367.
      View in: PubMed
    3. Coulson RL, Powell WT, Yasui DH, Dileep G, Resnick J, LaSalle JM. Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN. Hum Mol Genet. 2018 Aug 14. PMID: 30124848.
      View in: PubMed
    4. Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali M, LaSalle JM, Medici V. Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease. Hum Mol Genet. 2018 Jul 16. PMID: 30010856.
      View in: PubMed
    5. Adhikari A, Copping NA, Onaga B, Pride MC, Coulson RL, Yang M, Yasui DH, LaSalle JM, Silverman JL. Cognitive deficits in the Snord116 deletion mouse model for Prader-Willi syndrome. Neurobiol Learn Mem. 2018 May 23. PMID: 29800646.
      View in: PubMed
    6. Vogel Ciernia A, Laufer BI, Dunaway KW, Mordaunt CE, Coulson RL, Totah TS, Stolzenberg DS, Frahm JC, Singh-Taylor A, Baram TZ, LaSalle JM, Yasui DH. Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches. Epigenetics. 2018 May 10; 1-13. PMID: 29613827.
      View in: PubMed
    7. Coulson RL, Yasui DH, Dunaway KW, Laufer BI, Vogel Ciernia A, Zhu Y, Mordaunt CE, Totah TS, LaSalle JM. Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. Nat Commun. 2018 Apr 24; 9(1):1616. PMID: 29691382.
      View in: PubMed
    8. Coulson RL, LaSalle JM. Epigenetics of Circadian Rhythms in Imprinted Neurodevelopmental Disorders. Prog Mol Biol Transl Sci. 2018; 157:67-92. PMID: 29933957.
      View in: PubMed
    9. Dou J, Schmidt RJ, Benke KS, Newschaffer C, Hertz-Picciotto I, Croen LA, Iosif AM, LaSalle JM, Fallin MD, Bakulski KM. Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation. Epigenetics. 2018; 13(1):108-116. PMID: 29451060.
      View in: PubMed
    10. Vogel Ciernia A, Careaga M, LaSalle JM, Ashwood P. Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism. Glia. 2018 03; 66(3):505-521. PMID: 29134693.
      View in: PubMed
    11. Lopez SJ, Dunaway K, Islam MS, Mordaunt C, Vogel Ciernia A, Meguro-Horike M, Horike SI, Segal DJ, LaSalle JM. UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons. Epigenetics. 2017; 12(11):982-990. PMID: 28925810.
      View in: PubMed
    12. Copping NA, Christian SGB, Ritter DJ, Islam MS, Buscher N, Zolkowska D, Pride MC, Berg EL, LaSalle JM, Ellegood J, Lerch JP, Reiter LT, Silverman JL, Dindot SV. Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome. Hum Mol Genet. 2017 10 15; 26(20):3995-4010. PMID: 29016856.
      View in: PubMed
    13. Vogel Ciernia A, Pride MC, Durbin-Johnson B, Noronha A, Chang A, Yasui DH, Crawley JN, LaSalle JM. Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering. Hum Mol Genet. 2017 05 15; 26(10):1839-1854. PMID: 28334953.
      View in: PubMed
    14. Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Freeland DM, Miller R, Murphy SK. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environ Health Perspect. 2017 04; 125(4):511-526. PMID: 28362264.
      View in: PubMed
    15. Dunaway K, Goorha S, Matelski L, Urraca N, Lein PJ, Korf I, Reiter LT, LaSalle JM. Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns. Stem Cells. 2017 04; 35(4):981-988. PMID: 28032673.
      View in: PubMed
    16. Crary-Dooley FK, Tam ME, Dunaway KW, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies. Epigenetics. 2017 03 04; 12(3):206-214. PMID: 28055307.
      View in: PubMed
    17. Schroeder DI, Schmidt RJ, Crary-Dooley FK, Walker CK, Ozonoff S, Tancredi DJ, Hertz-Picciotto I, LaSalle JM. Placental methylome analysis from a prospective autism study. Mol Autism. 2016; 7:51. PMID: 28018572.
      View in: PubMed
    18. Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep. 2016 12 13; 17(11):3035-3048. PMID: 27974215.
      View in: PubMed
    19. Schmidt RJ, Schroeder DI, Crary-Dooley FK, Barkoski JM, Tancredi DJ, Walker CK, Ozonoff S, Hertz-Picciotto I, LaSalle JM. Self-reported pregnancy exposures and placental DNA methylation in the MARBLES prospective autism sibling study. Environ Epigenet. 2016 Dec; 2(4). PMID: 28781890.
      View in: PubMed
    20. Medici V, Kieffer DA, Shibata NM, Chima H, Kim K, Canovas A, Medrano JF, Islas-Trejo AD, Kharbanda KK, Olson K, Su RJ, Islam MS, Syed R, Keen CL, Miller AY, Rutledge JC, Halsted CH, LaSalle JM. Wilson Disease: Epigenetic effects of choline supplementation on phenotype and clinical course in a mouse model. Epigenetics. 2016 Nov; 11(11):804-818. PMID: 27611852.
      View in: PubMed
    21. Veeraragavan S, Wan YW, Connolly DR, Hamilton SM, Ward CS, Soriano S, Pitcher MR, McGraw CM, Huang SG, Green JR, Yuva LA, Liang AJ, Neul JL, Yasui DH, LaSalle JM, Liu Z, Paylor R, Samaco RC. Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome. Hum Mol Genet. 2016 08 01; 25(15):3284-3302. PMID: 27365498.
      View in: PubMed
    22. Vogel Ciernia A, LaSalle J. The landscape of DNA methylation amid a perfect storm of autism aetiologies. Nat Rev Neurosci. 2016 07; 17(7):411-23. PMID: 27150399.
      View in: PubMed
    23. Rube HT, Lee W, Hejna M, Chen H, Yasui DH, Hess JF, LaSalle JM, Song JS, Gong Q. Sequence features accurately predict genome-wide MeCP2 binding in vivo. Nat Commun. 2016 Mar 24; 7:11025. PMID: 27008915; PMCID: PMC4820824.
    24. Crawley JN, Heyer WD, LaSalle JM. Autism and Cancer Share Risk Genes, Pathways, and Drug Targets. Trends Genet. 2016 Mar; 32(3):139-146. PMID: 26830258; PMCID: PMC4769654 [Available on 03/01/17].
    25. LaSalle JM, Reiter LT, Chamberlain SJ. Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders. Epigenomics. 2015 Oct; 7(7):1213-28. PMID: 26585570; PMCID: PMC4709177 [Available on 10/01/16].
    26. Schroeder DI, Jayashankar K, Douglas KC, Thirkill TL, York D, Dickinson PJ, Williams LE, Samollow PB, Ross PJ, Bannasch DL, Douglas GC, LaSalle JM. Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas. PLoS Genet. 2015 Aug; 11(8):e1005442. PMID: 26241857; PMCID: PMC4524645.
    27. Powell WT, LaSalle JM. Epigenetic mechanisms in diurnal cycles of metabolism and neurodevelopment. Hum Mol Genet. 2015 Oct 15; 24(R1):R1-9. PMID: 26105183; PMCID: PMC4683361 [Available on 10/15/16].
    28. Li MM, Addepalli B, Tu MJ, Chen QX, Wang WP, Limbach PA, LaSalle JM, Zeng S, Huang M, Yu AM. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity. Drug Metab Dispos. 2015 Jul; 43(7):1129-36. PMID: 25934574; PMCID: PMC4468437.
    29. Lee W, Yun JM, Woods R, Dunaway K, Yasui DH, Lasalle JM, Gong Q. MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons. Hum Mol Genet. 2014 Dec 01; 23(23):6366-74. PMID: 25008110; PMCID: PMC4222369.
    30. Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, LaSalle JM, Halsted CH, Keen CL, Medici V. Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease. Int J Mol Sci. 2014 May 07; 15(5):8004-23. PMID: 24810691; PMCID: PMC4057715.
    31. Selmi C, Cavaciocchi F, Lleo A, Cheroni C, De Francesco R, Lombardi SA, De Santis M, Meda F, Raimondo MG, Crotti C, Folci M, Zammataro L, Mayo MJ, Bach N, Shimoda S, Gordon SC, Miozzo M, Invernizzi P, Podda M, Scavelli R, Martin MR, Seldin MF, Lasalle JM, Gershwin ME. Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis. Front Immunol. 2014; 5:128. PMID: 24734033; PMCID: PMC3975093.
    32. Conant KD, Finucane B, Cleary N, Martin A, Muss C, Delany M, Murphy EK, Rabe O, Luchsinger K, Spence SJ, Schanen C, Devinsky O, Cook EH, LaSalle J, Reiter LT, Thibert RL. A survey of seizures and current treatments in 15q duplication syndrome. Epilepsia. 2014 Mar; 55(3):396-402. PMID: 24502430.
      View in: PubMed
    33. Yasui DH, Gonzales ML, Aflatooni JO, Crary FK, Hu DJ, Gavino BJ, Golub MS, Vincent JB, Carolyn Schanen N, Olson CO, Rastegar M, Lasalle JM. Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome. Hum Mol Genet. 2014 May 01; 23(9):2447-58. PMID: 24352790; PMCID: PMC3976336.
    34. Schroeder DI, LaSalle JM. How has the study of the human placenta aided our understanding of partially methylated genes? Epigenomics. 2013 Dec; 5(6):645-54. PMID: 24283879; PMCID: PMC3955088.
    35. Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease. Epigenetics. 2014 Feb; 9(2):286-96. PMID: 24220304; PMCID: PMC3962539.
    36. Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM. R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):13938-43. PMID: 23918391; PMCID: PMC3752217.
    37. Lasalle JM. Autism genes keep turning up chromatin. OA Autism. 2013 Jun 19; 1(2):14. PMID: 24404383.
      View in: PubMed
    38. Powell WT, Coulson RL, Crary FK, Wong SS, Ach RA, Tsang P, Alice Yamada N, Yasui DH, Lasalle JM. A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure. Hum Mol Genet. 2013 Nov 01; 22(21):4318-28. PMID: 23771028; PMCID: PMC3792690.
    39. LaSalle JM, Powell WT, Yasui DH. Epigenetic layers and players underlying neurodevelopment. Trends Neurosci. 2013 Aug; 36(8):460-70. PMID: 23731492; PMCID: PMC3735843.
    40. LaSalle JM. Epigenomic strategies at the interface of genetic and environmental risk factors for autism. J Hum Genet. 2013 Jul; 58(7):396-401. PMID: 23677056; PMCID: PMC3955092.
    41. Schroeder DI, Blair JD, Lott P, Yu HO, Hong D, Crary F, Ashwood P, Walker C, Korf I, Robinson WP, LaSalle JM. The human placenta methylome. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6037-42. PMID: 23530188; PMCID: PMC3625261.
    42. Yasui DH, Xu H, Dunaway KW, Lasalle JM, Jin LW, Maezawa I. MeCP2 modulates gene expression pathways in astrocytes. Mol Autism. 2013 Jan 25; 4(1):3. PMID: 23351786; PMCID: PMC3561260.
    43. Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Török NJ, Jiang JX, Havel PJ, Lönnerdal B, Kim K, Halsted CH. Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatology. 2013 Feb; 57(2):555-65. PMID: 22945834; PMCID: PMC3566330.
    44. Mitchell MM, Woods R, Chi LH, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder. Environ Mol Mutagen. 2012 Oct; 53(8):589-98. PMID: 22930557; PMCID: PMC3739306.
    45. Gonzales ML, Adams S, Dunaway KW, LaSalle JM. Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation. Mol Cell Biol. 2012 Jul; 32(14):2894-903. PMID: 22615490; PMCID: PMC3416191.
    46. Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, LaSalle JM. Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Hum Mol Genet. 2012 Jun 01; 21(11):2399-411. PMID: 22343140; PMCID: PMC3349420.
    47. Martins-Taylor K, Schroeder DI, LaSalle JM, Lalande M, Xu RH. Role of DNMT3B in the regulation of early neural and neural crest specifiers. Epigenetics. 2012 Jan 01; 7(1):71-82. PMID: 22207353; PMCID: PMC3329505.
    48. Scoles HA, Urraca N, Chadwick SW, Reiter LT, Lasalle JM. Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples. Mol Autism. 2011 Dec 12; 2(1):19. PMID: 22152151; PMCID: PMC3287113.
    49. Yasui DH, Scoles HA, Horike S, Meguro-Horike M, Dunaway KW, Schroeder DI, Lasalle JM. 15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain. Hum Mol Genet. 2011 Nov 15; 20(22):4311-23. PMID: 21840925; PMCID: PMC3196884.
    50. Schroeder DI, Lott P, Korf I, LaSalle JM. Large-scale methylation domains mark a functional subset of neuronally expressed genes. Genome Res. 2011 Oct; 21(10):1583-91. PMID: 21784875; PMCID: PMC3202276.
    51. Meguro-Horike M, Yasui DH, Powell W, Schroeder DI, Oshimura M, Lasalle JM, Horike S. Neuron-specific impairment of inter-chromosomal pairing and transcription in a novel model of human 15q-duplication syndrome. Hum Mol Genet. 2011 Oct 01; 20(19):3798-810. PMID: 21725066; PMCID: PMC3168289.
    52. LaSalle JM. A genomic point-of-view on environmental factors influencing the human brain methylome. Epigenetics. 2011 Jul; 6(7):862-9. PMID: 21617367; PMCID: PMC3154427.
    53. Artuso R, Papa FT, Grillo E, Mucciolo M, Yasui DH, Dunaway KW, Disciglio V, Mencarelli MA, Pollazzon M, Zappella M, Hayek G, Mari F, Renieri A, Lasalle JM, Ariani F. Investigation of modifier genes within copy number variations in Rett syndrome. J Hum Genet. 2011 Jul; 56(7):508-15. PMID: 21593744; PMCID: PMC3145144.
    54. Singleton MK, Gonzales ML, Leung KN, Yasui DH, Schroeder DI, Dunaway K, LaSalle JM. MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. Neurobiol Dis. 2011 Jul; 43(1):190-200. PMID: 21420494; PMCID: PMC3096744.
    55. Leung KN, Chamberlain SJ, Lalande M, LaSalle JM. Neuronal chromatin dynamics of imprinting in development and disease. J Cell Biochem. 2011 Feb; 112(2):365-73. PMID: 21268055; PMCID: PMC3090268.
    56. Mitchell MM, Lleo A, Zammataro L, Mayo MJ, Invernizzi P, Bach N, Shimoda S, Gordon S, Podda M, Gershwin ME, Selmi C, LaSalle JM. Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis. Epigenetics. 2011 Jan; 6(1):95-102. PMID: 20864813; PMCID: PMC3029486.
    57. Gonzales ML, LaSalle JM. The role of MeCP2 in brain development and neurodevelopmental disorders. Curr Psychiatry Rep. 2010 Apr; 12(2):127-34. PMID: 20425298.
      View in: PubMed
    58. LaSalle JM, Yasui DH. Evolving role of MeCP2 in Rett syndrome and autism. Epigenomics. 2009 Oct; 1(1):119-30. PMID: 20473347.
      View in: PubMed
    59. Leung KN, Vallero RO, DuBose AJ, Resnick JL, LaSalle JM. Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size. Hum Mol Genet. 2009 Nov 15; 18(22):4227-38. PMID: 19656775; PMCID: PMC2766290.
    60. Maezawa I, Swanberg S, Harvey D, LaSalle JM, Jin LW. Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci. 2009 Apr 22; 29(16):5051-61. PMID: 19386901; PMCID: PMC3436907.
    61. Swanberg SE, Nagarajan RP, Peddada S, Yasui DH, LaSalle JM. Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism. Hum Mol Genet. 2009 Feb 01; 18(3):525-34. PMID: 19000991.
      View in: PubMed
    62. Adegbola AA, Gonzales ML, Chess A, LaSalle JM, Cox GF. A novel hypomorphic MECP2 point mutation is associated with a neuropsychiatric phenotype. Hum Genet. 2009 Jan; 124(6):615-23. PMID: 18989701.
      View in: PubMed
    63. Hogart A, Wu D, LaSalle JM, Schanen NC. The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13. Neurobiol Dis. 2010 May; 38(2):181-91. PMID: 18840528; PMCID: PMC2884398.
    64. Hogart A, Patzel KA, LaSalle JM. Gender influences monoallelic expression of ATP10A in human brain. Hum Genet. 2008 Oct; 124(3):235-42. PMID: 18726118; PMCID: PMC2830741.
    65. Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008 Jun; 1(3):169-78. PMID: 19132145.
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    66. Kumar A, Kamboj S, Malone BM, Kudo S, Twiss JL, Czymmek KJ, LaSalle JM, Schanen NC. Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo. J Cell Sci. 2008 Apr 01; 121(Pt 7):1128-37. PMID: 18334558; PMCID: PMC2637154.
    67. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. PMID: 18394707; PMCID: PMC2475601.
    68. Yasui DH, Peddada S, Bieda MC, Vallero RO, Hogart A, Nagarajan RP, Thatcher KN, Farnham PJ, Lasalle JM. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc Natl Acad Sci U S A. 2007 Dec 04; 104(49):19416-21. PMID: 18042715; PMCID: PMC2148304.
    69. Hogart A, Nagarajan RP, Patzel KA, Yasui DH, Lasalle JM. 15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders. Hum Mol Genet. 2007 Mar 15; 16(6):691-703. PMID: 17339270; PMCID: PMC1934608.
    70. LaSalle JM. The odyssey of MeCP2 and parental imprinting. Epigenetics. 2007 Jan-Mar; 2(1):5-10. PMID: 17486180; PMCID: PMC1866173.
    71. LaSalle JM. The Odyssey of MeCP2 and parental imprinting. Epigenetics. 2007 Jan-Mar; 2(1):5-10. PMID: 17965611; PMCID: PMC1866173.
    72. Nagarajan RP, Hogart AR, Gwye Y, Martin MR, LaSalle JM. Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics. 2006 Oct-Dec; 1(4):e1-11. PMID: 17486179; PMCID: PMC1866172.
    73. Delgado IJ, Kim DS, Thatcher KN, LaSalle JM, Van den Veyver IB. Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients. BMC Med Genet. 2006 Jul 21; 7:61. PMID: 16859563; PMCID: PMC1569822.
    74. Peddada S, Yasui DH, LaSalle JM. Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome. Hum Mol Genet. 2006 Jun 15; 15(12):2003-14. PMID: 16682435; PMCID: PMC1931415.
    75. Thatcher KN, LaSalle JM. Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2. Epigenetics. 2006 Jan-Mar; 1(1):24-31. PMID: 17464364; PMCID: PMC1857283.
    76. Thatcher KN, Peddada S, Yasui DH, Lasalle JM. Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples. Hum Mol Genet. 2005 Mar 15; 14(6):785-97. PMID: 15689352.
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    77. LaSalle JM, Hogart A, Thatcher KN. Rett syndrome: a Rosetta stone for understanding the molecular pathogenesis of autism. Int Rev Neurobiol. 2005; 71:131-65. PMID: 16512349.
      View in: PubMed
    78. Samaco RC, Hogart A, LaSalle JM. Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum Mol Genet. 2005 Feb 15; 14(4):483-92. PMID: 15615769; PMCID: PMC1224722.
    79. Braunschweig D, Simcox T, Samaco RC, LaSalle JM. X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain. Hum Mol Genet. 2004 Jun 15; 13(12):1275-86. PMID: 15115765.
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    80. Samaco RC, Nagarajan RP, Braunschweig D, LaSalle JM. Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders. Hum Mol Genet. 2004 Mar 15; 13(6):629-39. PMID: 14734626.
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    81. LaSalle JM. Paradoxical role of methyl-CpG-binding protein 2 in Rett syndrome. Curr Top Dev Biol. 2004; 59:61-86. PMID: 14975247.
      View in: PubMed
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